Resuscitation plus最新文献

{"title":"Real-world adoption and use of a ventilation feedback device during out-of-hospital cardiac arrest: a population-based observational study from a French prehospital system","authors":"Jean-Baptiste Pretalli,&nbsp;Marie Da Cunha,&nbsp;Saïd Hachimi-Idrissi,&nbsp;Laure-Estelle Piller,&nbsp;Abdo Khoury","doi":"10.1016/j.resplu.2026.101465","DOIUrl":"10.1016/j.resplu.2026.101465","url":null,"abstract":"<div><h3>Background</h3><div>Ventilation quality during cardiopulmonary resuscitation remains highly variable despite clear guidelines. Ventilation feedback devices have shown substantial improvements in simulated settings, but real-world implementation data remain limited.</div><div>We aimed to evaluate real-world adoption and use of a ventilation feedback device during out-of-hospital cardiac arrest (OHCA) management in a French prehospital system.</div></div><div><h3>Methods</h3><div>We conducted a retrospective, population-based observational study of adult OHCAs jointly managed by firefighters and Mobile Intensive Care Unit teams in the Doubs region. Cases from 2022 (pre-implementation) and 2024 (post-implementation) were analysed. The primary outcome was device utilisation. Secondary outcomes included return of spontaneous circulation, survival, and neurological status, reported descriptively and exploratorily.</div></div><div><h3>Results</h3><div>Among 756 patients, 190 (2022) and 166 (2024) met the inclusion criteria. Despite a protocol mandating its systematic use, the device was used in 48/166 (28.9%) cases.</div><div>Baseline characteristics and resuscitation variables were comparable between groups. Exploratory analyses showed return of spontaneous circulation in 25.0% with device versus 16.1% without (unadjusted odds ratio (OR) = 1.74 confidence interval (CI) 95% [0.77; 3.93]), and survival at day 30 in 10.4% versus 4.2% (unadjusted OR = 2.63 [0.72; 9.53]). Favourable neurological outcome at day 30 was observed in 10.4% versus 3.4% (unadjusted OR = 3.28 [0.84; 12.8]). Given the observational design and limited sample size, these findings should be interpreted as hypothesis-generating.</div></div><div><h3>Conclusion</h3><div>This study highlights a discrepancy between protocol and real-world use of a ventilation feedback device during out-of-hospital cardiac arrest. They underscore the need to better understand implementation factors to inform future studies evaluating clinical effectiveness. Future research should incorporate robust implementation strategies and standardised ventilation parameters.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"31 ","pages":"Article 101465"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148935746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Out-of-hospital cardiac arrest incidence and temporal trends in Ecuador: a national cross-sectional study","authors":"Ricardo S. Pinto-Villalba,&nbsp;Mónica Martínez,&nbsp;Carlos Guerrero-Calderón,&nbsp;Jefferson Reinoso,&nbsp;Carla Zamora,&nbsp;Rene M. Abarca-Tenemasa","doi":"10.1016/j.resplu.2026.101467","DOIUrl":"10.1016/j.resplu.2026.101467","url":null,"abstract":"<div><h3>Background</h3><div>Out-of-hospital cardiac arrest (OHCA) is a leading global cause of mortality, with wide regional disparities in incidence. While high-income countries have national OHCA registries national data from Latin America remain scarce, limiting context-specific emergency planning.</div></div><div><h3>Objective</h3><div>To describe the incidence and temporal trends of confirmed EMS-attended OHCA in Ecuador from 2022 to 2024, and to explore ecological correlations with cardiovascular and socioeconomic indicators.</div></div><div><h3>Methods</h3><div>We conducted a retrospective observational study, following STROBE guidelines, using confirmed OHCA cases recorded by the Integrated Security Service (SIS ECU 9-1-1) from 1 January 2022 to 31 December 2024. Temporal and geographic trends were analysed and visualised. Incidence rates were calculated per 100,000 inhabitants, and province-year ecological associations with hypertension, diabetes, acute myocardial infarction and gross value added (GVA) were assessed using Spearman’s rank correlation.</div></div><div><h3>Results</h3><div>SIS ECU 9-1-1 recorded 936,784 emergency events, of which 9942 (1.06%) were confirmed EMS-attended OHCA cases. National incidence decreased from 20.51 per 100,000 inhabitants in 2022 to 18.71 in 2023 and 16.52 in 2024. Higher adjusted rates were observed in Loja, Imbabura and Carchi, while Guayas showed persistently low rates. OHCA correlated moderately with diabetes (rho = 0.463; <em>p</em> &lt; 0.001) and weakly but significantly with acute myocardial infarction (rho = 0.382; <em>p</em> &lt; 0.001). Associations with hypertension and GVA were weak and non-significant.</div></div><div><h3>Conclusions</h3><div>This first national epidemiological profile of OHCA in Ecuador shows declining incidence, geographical heterogeneity and relevant ecological associations with diabetes and acute myocardial infarction. The findings support a national OHCA registry and targeted prevention and emergency-response strategies.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"31 ","pages":"Article 101467"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148935793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypoxic hepatitis after cardiac arrest is associated with 30-day mortality, poor neurological outcome and non-occlusive mesenteric ischemia","authors":"Peter Hunyady,&nbsp;Asieb Sekandarzad,&nbsp;Dawid L. Staudacher,&nbsp;Tobias Wengenmayer,&nbsp;Hendrik Luxenburger,&nbsp;Robert Thimme,&nbsp;Katharina Mueller-Peltzer,&nbsp;Alexander Supady,&nbsp;Dominik Bettinger","doi":"10.1016/j.resplu.2026.101472","DOIUrl":"10.1016/j.resplu.2026.101472","url":null,"abstract":"<div><h3>Background and aims</h3><div>Abdominal organ dysfunction after cardiac arrest may reflect hepatosplanchnic hypoperfusion. Hypoxic hepatitis may indicate severe systemic hypoperfusion and a hepatosplanchnic ischemic phenotype. We assessed hypoxic hepatitis occurrence and associations with 30-day mortality, favourable neurological outcome and non-occlusive mesenteric ischemia after conventional and extracorporeal cardiopulmonary resuscitation (CPR, ECPR).</div></div><div><h3>Methods</h3><div>We performed a retrospective single-centre cohort study of adult patients admitted after cardiac arrest between 11/2020 and 02/2026. Hypoxic hepatitis was defined as peak aspartate or alanine aminotransferase ≥20 times the sex-specific upper limit of normal within 72 h after collapse, after exclusion of primary non-hypoxic hepatopathy. Analyses were restricted to patients alive at 72 h and performed separately for CPR and ECPR using adjusted Cox proportional hazards and logistic regression models.</div></div><div><h3>Results</h3><div>Among 835 patients, hypoxic hepatitis occurred in 58/702 CPR patients (8.3%) and 29/133 ECPR patients (21.8%). In the CPR cohort, hypoxic hepatitis was associated with higher 30-day mortality (adjusted HR 1.63, 95% CI 1.11–2.42), lower odds of favourable neurological survival (adjusted OR 0.33, 95% CI 0.17–0.64) and higher odds of non-occlusive mesenteric ischemia (adjusted OR 7.02, 95% CI 2.61–18.89). Corresponding adjusted estimates in ECPR patients were HR 2.65 (95% CI 1.44–4.90), OR 0.09 (95% CI 0.02–0.33) and OR 3.99 (95% CI 1.35–11.78), respectively.</div></div><div><h3>Conclusion</h3><div>Among patients alive 72 h after cardiac arrest, hypoxic hepatitis was associated with increased 30-day mortality, poor neurological outcome and non-occlusive mesenteric ischemia and may help identify a hepatosplanchnic high-risk phenotype after both CPR and ECPR.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"31 ","pages":"Article 101472"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148952756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of ventilation feedback devices compared with a reference standard during asynchronous ventilation with continuous chest compressions in a simulated cardiac arrest: a prospective non-randomized cross-over study","authors":"Christophe Duchatelet,&nbsp;Kristof Segher,&nbsp;Thomas Tackaert,&nbsp;Maxim Vanwulpen,&nbsp;Bert Ingels,&nbsp;Dimitri Muylaert,&nbsp;Said Hachimi-Idrissi","doi":"10.1016/j.resplu.2026.101475","DOIUrl":"10.1016/j.resplu.2026.101475","url":null,"abstract":"<div><h3>AIM</h3><div>This study aimed to evaluate the accuracy of two commercially available ventilation feedback devices (VFD) in measuring ventilation rate and tidal volume during simulated cardiopulmonary resuscitation (CPR) with continuous chest compressions and asynchronous ventilations in the presence of reversed airflow.</div></div><div><h3>Methods</h3><div>Prospective, simulation-based, non-randomized cross-over study. Twenty emergency department nurse practitioners performed manual ventilation on an intubated high-fidelity manikin during two 1-minute trials (one per device), targeting 10 breaths/min during continuous chest compressions (100–120/min). Ventilation parameters displayed by EOLifeX® and AccuVent® were compared with measurements from a high-fidelity pneumotachograph (HFRP). Data is presented as mean (standard deviation, min–max range). CI = confidence interval.</div></div><div><h3>Results</h3><div><strong>EOLifeX®:</strong> From HFRP flow data, 254 ventilations were identified (rate 12/min [1; 8–14], tidal volume 544 mL [32; 482–604]). All showed reversed airflow with an average of 49 mL [13; 19–72]. VFD displayed values overestimated ventilation rate and underestimated tidal volume (111/min [5; 99–121] and 104 mL [14; 68–240]; biases +99 breaths/min, 95% CI 96.6–101.4, and −440 mL, 95% CI −456.3 to −423.7). <strong>AccuVent®:</strong> From HFRP flow data, a total of 222 ventilations were identified (rate 12/min [1; 8–13], tidal volume 532 mL [35; 460–614]). All showed reversed airflow with an average of 56 mL [15; 22–78]. VFD displayed values were similar for rate (12/min [1; 8–13]) but underestimated tidal volume (360 mL [24; 292–398]; bias −172 mL, 95% CI −191.9 to −152.1).</div></div><div><h3>Conclusion</h3><div>During simulated CPR with continuous compressions and asynchronous ventilations, VFDs demonstrated clinically relevant inaccuracies. Validation under realistic resuscitation conditions are needed.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"31 ","pages":"Article 101475"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148952710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temporal trends in chest compression quality during a metronome-guided CPR simulation: a secondary analysis of the RITMICO study","authors":"Giuliana Monachino,&nbsp;Valentina Guerini Giusteri,&nbsp;Ruggero Cresta,&nbsp;Alessia Currao,&nbsp;Enrico Baldi,&nbsp;Simone Savastano,&nbsp;Andrea Cortegiani,&nbsp;Mariachiara Ippolito,&nbsp;Alessandra Gargano,&nbsp;Camilla Metelmann,&nbsp;Bibiana Metelmann,&nbsp;Carlos Roman Hölzing,&nbsp;Julian Ganter,&nbsp;Michael Mueller,&nbsp;Claudio Benvenuti,&nbsp;Stefania Tomola,&nbsp;Pierangelo Pinetti,&nbsp;Pier Luigi Ingrassia,&nbsp;Giulio Conte,&nbsp;Francesca D Faraci,&nbsp;Maria Luce Caputo","doi":"10.1016/j.resplu.2026.101461","DOIUrl":"10.1016/j.resplu.2026.101461","url":null,"abstract":"<div><h3>Background</h3><div>High-quality cardiopulmonary resuscitation (CPR) is essential for improving outcomes after out-of-hospital cardiac arrest. The RITMICO study evaluated a newly developed double-click metronome, providing separate auditory cues for the compression and release phases, compared with a standard metronome. This secondary analysis investigated temporal changes in chest compression (CC) quality during prolonged manikin-based CPR simulations and explored factors associated with these trajectories.</div></div><div><h3>Methods</h3><div>477 volunteers (54% male; mean age 34 ± 12 years) were included in the analysis. Compression depth, compression rate, and chest compression release velocity (CCRV) were recorded using an automated external defibrillator with CC quality analysis technology. Simulations were divided into 21 consecutive 5-s intervals, and median values for each metric were analyzed using linear mixed-effects models with subject-specific random effects.</div></div><div><h3>Results</h3><div>Compression depth and CCRV progressively declined over time, indicating early deterioration in CPR quality during prolonged compressions. Compared with the standard metronome, the double-click metronome produced consistently higher values for all CPR quality metrics throughout the simulation (all <em>p</em> &lt; 0.05). It also delayed the decline of CCRV below the suggested threshold, indicating better preservation of chest recoil quality. Male participants maintained compression depth and CCRV longer than female participants.</div></div><div><h3>Conclusions</h3><div>CPR quality deteriorated early during prolonged simulated chest compressions, particularly with respect to chest recoil. The use of a double-click metronome was associated with better preservation of CPR quality over time and a later deterioration in CCRV. These findings support a potential role for the double-click metronome in maintaining CPR quality during prolonged resuscitation, although confirmation in real-world clinical settings is needed.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"31 ","pages":"Article 101461"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148935864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The European Resuscitation Council course strategy project – developing courses fit for the future","authors":"Robert Greif,&nbsp;Andrew S. Lockey,&nbsp;Carsten Lott","doi":"10.1016/j.resplu.2026.101469","DOIUrl":"10.1016/j.resplu.2026.101469","url":null,"abstract":"","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"31 ","pages":"Article 101469"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148935800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An innovative porcine model of pediatric drowning","authors":"Chelsea Morin,&nbsp;Megan O’Reilly,&nbsp;Tze-Fun Lee,&nbsp;Georg M Schmölzer","doi":"10.1016/j.resplu.2026.101460","DOIUrl":"10.1016/j.resplu.2026.101460","url":null,"abstract":"<div><div>Worldwide, children between the ages of 0 and 4 years have the highest rate of drowning incidents. Hypoxia is the most detrimental consequence of drowning incidents. Therefore, restoration of oxygenation, ventilation, and perfusion is of the utmost importance and should be restored as rapidly as possible via adequate airway management and respiratory support during cardiopulmonary resuscitation (CPR). Optimizing the CPR technique used following drowning incidents in children, has the potential to improve survival. There is currently extremely limited scientific knowledge regarding the optimal CPR technique for pediatric drowning victims. Indeed, there is no pediatric animal drowning model currently available, which makes our model unique. Our model lays the foundation for future pre-clinical and clinical studies and will also provide critical scientific knowledge used to guide resuscitation recommendations.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"31 ","pages":"Article 101460"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148935866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Introducing the first link of the Chain of Survival to preschool children: a feasibility observation","authors":"Burak Çelik,&nbsp;Funda Yusufoğlu,&nbsp;Kadir Emre Yakışık,&nbsp;Nilgün Göleş","doi":"10.1016/j.resplu.2026.101456","DOIUrl":"10.1016/j.resplu.2026.101456","url":null,"abstract":"","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"31 ","pages":"Article 101456"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148935867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of head and thorax elevation on respiratory mechanics during cardiopulmonary resuscitation: a multi-model study","authors":"Nicolas Segond,&nbsp;Arnaud Lesimple,&nbsp;Lilian Barlet,&nbsp;Laura Polard,&nbsp;Fanny Lidouren,&nbsp;Emmanuel Charbonney,&nbsp;Dominique Savary,&nbsp;François Morin,&nbsp;Alexandre Bellier,&nbsp;Renaud Tissier,&nbsp;Jean-Christophe Richard,&nbsp;Guillaume Debaty","doi":"10.1016/j.resplu.2026.101464","DOIUrl":"10.1016/j.resplu.2026.101464","url":null,"abstract":"<div><h3>Background</h3><div>The impact on ventilation of head and thorax elevation (HTE) and the use of an impedance threshold device (ITD) during cardiopulmonary resuscitation (CPR) remains poorly understood. The aim was to describe the impact on ventilation and absolute lung volumes of HTE vs. horizontal (FLAT) positions, with or without ITD use, across multiple cardiac arrest experimental models.</div></div><div><h3>Methods</h3><div>This was a cross-over experimental trial conducted using three models: pigs, Thiel-embalmed cadavers, and thawed fresh-frozen cadavers. Two protocols were applied in a 1:1 randomized order: FLAT and HTE positions first, with or without ITD. Primary outcome was the calculation of absolute loss of lung volume (Vloss) below the functional residual capacity. Airway opening pressure (AOP) and respiratory system compliance (Crs) were also calculated, both assessed before CPR initiation. Linear mixed models were used for statistical analysis.</div></div><div><h3>Results</h3><div>Eight pigs and eight cadavers (4 Thiel, 4 fresh-frozen) were included. In the linear mixed model, there was a significant difference for Vloss for FLAT vs. HTE (<em>p</em> = 0.05) with an estimate of 43.9 mL (95%CI: 1.41; 86.4), while no significant difference was observed comparing ITD vs. no-ITD (<em>p</em> = 0.28) with an estimate of 23.6 mL (95%CI: −18.9; 66.1). In cadavers, AOP was not significantly different: HTE: 5.9 (2.9–10.3) vs. FLAT: 8.1 (6.4–11.5) cmH₂O (<em>p</em> = 0.07). Crs was not significantly different: HTE: 30.9 (21.3–34.4) vs. FLAT: 26.2 (24.0–30.3) mL/cmH₂O (<em>p</em> = 0.2).</div></div><div><h3>Conclusions</h3><div>In this multi-model study, HTE during CPR limits loss of lung volume below functional residual capacity.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"31 ","pages":"Article 101464"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148935810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of a smartphone application on dispatcher-assisted CPR and AED response in simulated out-of-hospital cardiac arrest","authors":"Duangpon Thepmanee,&nbsp;Pramote Papukdee,&nbsp;Rossakorn Klaiangthong","doi":"10.1016/j.resplu.2026.101471","DOIUrl":"10.1016/j.resplu.2026.101471","url":null,"abstract":"<div><h3>Objective</h3><div>Early bystander cardiopulmonary resuscitation (CPR) and rapid automated external defibrillator (AED) use are key determinants of survival following out-of-hospital cardiac arrest (OHCA). Smartphone applications may enhance dispatcher-assisted CPR (DA-CPR) and facilitate early AED access; however, evidence regarding their effectiveness in standardized simulation settings remains limited. This study evaluated the effectiveness of a smartphone application for DA-CPR and AED response during simulated OHCA.</div></div><div><h3>Methods</h3><div>This randomized simulation-based study was conducted using standardized OHCA scenarios in a controlled simulation environment. Fifty emergency medical dispatch personnel and 190 trained lay responders were randomly assigned to either a smartphone application group or a standard practice group. Primary outcomes were time to CPR initiation and time to first AED shock. Secondary outcomes included time to OHCA recognition, time to scenario completion, and high-quality CPR performance. Outcomes were compared using independent t-tests or Welch’s t-tests, as appropriate.</div></div><div><h3>Results</h3><div>Among dispatchers (<em>n</em> = 50), smartphone application use was associated with a shorter time to CPR initiation than the control condition (mean difference [MD], −0.56 min; 95% confidence interval [CI], −1.05 to −0.07; <em>p</em> = 0.026). Among lay responders (<em>n</em> = 190), application use was associated with shorter times to OHCA recognition (MD, −0.13 min; 95% CI, −0.21 to −0.05; <em>p</em> = 0.001) and scenario completion (MD, −0.24 min; 95% CI, −0.42 to −0.06; <em>p</em> = 0.011), but a longer time to CPR initiation (MD, 0.24 min; 95% CI, 0.01–0.47; <em>p</em> = 0.038). No statistically significant between-group differences were observed in the time to first AED shock or overall high-quality CPR performance.</div></div><div><h3>Conclusion</h3><div>In standardized simulated OHCA scenarios, use of the MySOS app was associated with a shorter time to first compression among dispatchers but a longer time to first compression among laypersons. No significant association was observed between MySOS use and time to first shock.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"31 ","pages":"Article 101471"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148952755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}