Medical archives (Sarajevo, Bosnia and Herzegovina)最新文献

{"title":"The Comparison of Serum Interleukin-8 Levels Based on Severity of Liver Cirrhosis.","authors":"Imelda Rey, Rustam Effendi-Ys, Khairani Sukatendel","doi":"10.5455/medarh.2024.78.92-94","DOIUrl":"https://doi.org/10.5455/medarh.2024.78.92-94","url":null,"abstract":"<p><strong>Background: </strong>The molecule known as Interleukin-8 (IL-8), a chemotactic leukocyte, has been found to have a crucial role in the perpetuation of the inflammatory environment that is associated with hepatitis B virus (HBV) infection, as well as in the development of liver cirrhosis and cancer.</p><p><strong>Objective: </strong>The aim of this study was to carefully examine the role of IL-8 in the inflammatory reaction and to compare the levels based on the severity of liver cirrhosis.</p><p><strong>Methods: </strong>The study was conducted from February 2018 to September 2018 at the Gastroenterohepatology Division, Internal medicine Department, Faculty of Medicine, Universitas Sumatera Utara. The study was designed as an analytic comparative, cross-sectional study. The liver cirrhosis patients who participated in this study met the inclusion criteria and provided informed consent.</p><p><strong>Results: </strong>A total of 70 patients were included in the study, from which we identified 1 individual with child-pugh A, 28 individuals with child-pugh B, and 41 individuals with child-pugh C. The serum level of IL-8 was found to be 98 (11-320) (pg/ml). The IL-8 levels between child-pugh B and C patients did not exhibit any noteworthy differences during our analysis (p = 0.109, p>0.05).</p><p><strong>Conclusion: </strong>There is no notable inequality in the levels of IL-8 across different stages of liver cirrhosis.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 2","pages":"92-94"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10983089/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140863010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Applications of Artificial Intelligence and Machine Learning in Emergency Medicine Triage - A Systematic Review.","authors":"Qasem Ahmed Almulihi, Abdulaziz Adel Alquraini, Fatimah Ahmed Ali Almulihi, Abdullah Abdulaziz Alzahid, Saleh Saeed Al Jathnan Al Qahtani, Mohamed Almulhim, Saeed Hussain Saeed Alqhtani, Faisal Mohammed Nafea Alnafea, Saad Ali Saad Mushni, Nasser Abdullah Alaqil, Mohammad Ibrahim Faya Assiri, Nisreen H Maghraby","doi":"10.5455/medarh.2024.78.198-206","DOIUrl":"10.5455/medarh.2024.78.198-206","url":null,"abstract":"<p><strong>Background: </strong>Overcrowding in Emergency departments adversely impacts efficiency, patient outcomes, and resource allocation. Accurate triage systems are essential for prioritizing care and optimizing resources. While traditional methods provide a foundation, they often lack precision in addressing modern healthcare complexities. Artificial intelligence (AI) and machine learning (ML) offer advanced capabilities to enhance triage accuracy, improve patient prioritization, and support clinical decision-making, addressing limitations of conventional approaches and paving the way for adaptive triage solutions.</p><p><strong>Objective: </strong>This systematic review aims to assess the use of artificial intelligence (AI) and machine learning (ML) in determining the outcomes of patients presenting in Emergency department (ED) triage.</p><p><strong>Methods: </strong>A systematic search was conducted on April 21, 2023, using electronic databases including PubMed/Medline, Cochrane Library, Ovid, and Google Scholar, without year restrictions. The main outcome of this review was to assess the use of AI and ML in the ED Triage. Articles that used different models of AI and ML to predict various outcomes of patients in the ED setting were included.</p><p><strong>Results: </strong>A total of 17 studies were included in this systematic review. Fifteen studies assessed the role of machine learning methods in emergency department triage, while two studies evaluated the role of AI and machine learning in prehospital triage. The results of our systematic review favor the use of machine learning methods and artificial intelligence in emergency triage. Machine learning models were found to be superior to conventional emergency severity score methods in determining triage, diagnosis, and early management of patients. Among the machine learning methods, the boosting model was slightly more effective.</p><p><strong>Conclusion: </strong>Our study supports the notion that AI and ML are the future of Emergency departments. They aid in predicting patient outcomes and determining appropriate management strategies more efficiently, thereby enhancing decision making in the ED.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 3","pages":"198-206"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11813208/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding Factors Influencing Length of Stay for Seizure Patients in Emergency Departments.","authors":"Mohammed AlMulhim, Faisal A AlGhamdi, Zeyad T Alharbi, Rakan S Alharbi, Abdulmalek A AlOmair, Abdulrahman A Alfryyan, Omar A AlGhamdi, Bader S AlSolo, Omnia AlMomen, Basmah Albloushi, Mariam Slosfoor, Mohammed Alghamdi, Nisreen H AlMaghraby","doi":"10.5455/medarh.2024.78.279-284","DOIUrl":"10.5455/medarh.2024.78.279-284","url":null,"abstract":"<p><strong>Background: </strong>Seizures are frequent presentations in emergency departments (EDs) requiring comprehensive evaluation and management. Prolonged length of stay (LOS) for seizure patients can impact patient care and healthcare resource utilization. Understanding the factors influencing LOS in this population is crucial for optimizing ED operations.</p><p><strong>Objective: </strong>This retrospective study aimed to analyze the factors influencing the LOS of seizure patients presenting to the ED.</p><p><strong>Methods: </strong>The study was conducted at an academic tertiary care center with a busy ED serving a diverse patient population. A retrospective cross-sectional design was employed to analyze data from electronic medical records of seizure patients aged ≥18 years presenting to the ED between 1/1/2020 and 31/12/2022. Data were collected on patient demographics, clinical characteristics, including seizure type, medication adherence, comorbidities, and diagnostic interventions. Statistical analysis included chi-square tests and logistic regression to identify significant associations between variables and LOS.</p><p><strong>Results: </strong>Of the 121 seizure patients included, factors significantly associated with prolonged LOS (>4 hours) included generalized tonic-clonic seizures, non-compliance to medication, breakthrough seizures, and diagnostic interventions such as CT head scans and neurology consultations. Conversely, known cases of seizure and absence of comorbidities were associated with shorter LOS (≤4 hours).</p><p><strong>Conclusion: </strong>Our study identifies several factors influencing the LOS for seizure patients in the ED, providing insights for optimizing patient care and resource allocation. Strategies aimed at addressing these factors may lead to improved efficiency and better outcomes for seizure patients in the ED.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 4","pages":"279-284"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11838826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143470346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of <i>Phaleria Macrocarpa</i> (Scheff.) Boerl Leaf Ethanol Extract on Serum IL-6 and TNF-α Levels in Diabetic Rats.","authors":"Ira Cinta Lestari,&nbsp;Dharma Lindarto,&nbsp;Syafruddin Ilyas,&nbsp;Tri Widyawati,&nbsp;Mustofa,&nbsp;Nelva Karmila Jusuf,&nbsp;Poppy Anjelisa Zaitun Hasibuan,&nbsp;Lambok Siahaan,&nbsp;Muhammad Rusda,&nbsp;Mustafa Mahmud Amin","doi":"10.5455/medarh.2023.77.254-257","DOIUrl":"10.5455/medarh.2023.77.254-257","url":null,"abstract":"<p><strong>Background: </strong>Hyperglycemia conditions in diabetes mellitus (DM) can turn on pro-inflammatory cytokines like IL-6 and TNF-α. These cytokines play a role in insulin resistance and the development of DM complications. People in Indonesia have used <i>Phaleria macrocarpa</i> to treat diabetes, but the leaf of this plant has not been studied to see if it can reduce inflammation.</p><p><strong>Objective: </strong>This study aims to analyze the effect of ethanolic extract of <i>Phaleria macrocarpa</i> leaves (EEPML) in serum IL-6 and TNF-α levels of diabetic rats.</p><p><strong>Methods: </strong>This study was an experiment with a post-test-only control group design. Thirty 8-week-old male Wistar rats were used in the study. They were split into six groups: K1 was the normal control group; K2 was the DM control group; K3, K4, and K5 were given EEPML at doses of 125, 250, and 500 mg/KgBW; and K6 was given metformin 45 mg/KgBW orally once a day for 14 days. A high-fat diet and a 30 mg/KgBWi.p injection of streptozotocin were used to make the diabetic rat model. ELISA method for measuring serum IL-6 and TNF-α levels. The Kruskal-Wallis and the Mann-Whitney test were used to examine the differences between the groups.</p><p><strong>Results: </strong>There were significant differences between treatment groups in the mean levels of serum IL-6 (p=0.017), but there were no significant differences in the mean levels of serum TNF-α (p>0.05).</p><p><strong>Conclusion: </strong>Administration of <i>Phaleria macrocarpa</i> leaf ethanol extract 125 mg/KgBW reduced serum IL-6 levels but could not significantly reduce serum TNF-α levels in diabetic rats.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"77 4","pages":"254-257"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ea/04/medarch-77-254.PMC10591243.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50159638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Affecting Length of Stay in Pediatric Emergency Department in a Teaching Hospital in Saudi Arabia.","authors":"Abdullah A Yousef,&nbsp;Mohammed H Al Qahtani,&nbsp;Abdullah K Al-Mutairi,&nbsp;Faisal O AlQurashi,&nbsp;Reem S AlOmar,&nbsp;Nouf A AlShamlan,&nbsp;Malak A Al Shammari,&nbsp;Hannen A Yousef","doi":"10.5455/medarh.2023.77.268-275","DOIUrl":"10.5455/medarh.2023.77.268-275","url":null,"abstract":"<p><strong>Background: </strong>Decreasing the number of Emergency Department patient visits for treatment, especially in non-urgent cases, is an international healthcare goal. The same applies for pediatric emergency rooms where the utilization of ED is much more than adults.</p><p><strong>Objective: </strong>We aim to measure the length of stay for all pediatric patients and examine the factors influencing it.</p><p><strong>Methods: </strong>A retrospective chart review study was conducted at the pediatric ED of King Fahd Hospital in the Eastern Province of Saudi Arabia. The study included all patients presented to the pediatric ED, between January 1, 2018, and December 31, 2018, aged from 1 day to < 14 years old. Data included patient's age, sex, season in which the patient presented in, chief complaint, time of presentation, and whether admission to the hospital ward was collected.</p><p><strong>Results: </strong>The total number of patients was 37,613. The median LOS was 100, interquartile range (IQR) = 53 - 272 minutes. Male pediatric patients were (55.12%). Among all patients, (32.04%) were toddlers, followed by school aged children (25.05%). The ER received more patients during the winter months followed by summer (32.92% and 24.72%, respectively). Fever was the most common complaint for all patients combined. For prolonged LOS patients, the most common complaints were respiratory related (23.44%). Pre-school children and school aged children were found to have a 5.49% and a 7.93% increased LOS when compared to toddlers (95% CI = 2.52 - 8.53, and 95% CI = 5.01 - 10.93, respectively). Summer was associated with a statistically significant increased LOS (% change = 28.92, 95% CI = 25.53 - 32.40). Morning shift was found to have a 7.89% increased LOS when compared to the evening shift. The highest increase in LOS was attributed to haematology related complaints (% change = 108.32, 95% CI = 85.69 - 133.71).</p><p><strong>Conclusion: </strong>Several pediatric LOS predicting factors have been identified; morning arrival, and presentation during summertime. Systemic factors such as staffing, and infrastructure can be modified and may affect the length of stay of patients. The implementation of these strategies and the evaluation of their impact on the length of stay in the pediatric emergency department require further investigation.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"77 4","pages":"268-275"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/57/08/medarch-77-268.PMC10591245.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50159639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical Activity Maintain Immune Response Through TLR-2/TLR-4 Gene Expression in Type-2 Diabetes Mellitus Patient at Medan City.","authors":"Yetty Machrina,&nbsp;Dwi Rita Anggraini,&nbsp;Yunita Sari Pane,&nbsp;Novita Sari Harahap,&nbsp;Gaurav Pant","doi":"10.5455/medarh.2023.77.276-280","DOIUrl":"10.5455/medarh.2023.77.276-280","url":null,"abstract":"<p><strong>Background: </strong>The Increasing in type-2 diabetes mellitus (T2DM) needs to solve comprehensively and holistically. Patients with T2DM should have self-coping due to lifestyle modification. Abdominal fat accumulation can release pro-inflammatory cytokine that leads TLR-2 and TLR-4 to the response. These two kinds of toll-like receptors exist on the monocyte surface membrane which is an innate immunity cell.</p><p><strong>Objective: </strong>The aims of this study were to get the profile of physical activity, metabolic state, and mononuclear cell response to the expression of the TLR2 and TLR4 genes in T2DM patients.</p><p><strong>Methods: </strong>It was a descriptive-analytic study with a cross-sectional study design. Thirty-two eligible patients with inclusion criteria participated as subjects. All subjects answered questions by IPAQ, and checked metabolic state with body composition analysis. The TLR2 and TLR4 gene expression was determined with quantitative Real- Time PCR.</p><p><strong>Results: </strong>This study result found that most T2DM patients were in a highly active category in which most of their activity was walking (light intensity). The average abdominal circumferences were 91.81 ± 15.4 cm, body fat percentage was 29.5 ± 8.8%, and fasting blood sugar was 187.07 ± 67.03 mg/dl. Mononuclear cells number were normal. The expression of the TLR2 gene was lower by 0.71 fold and TLR4 gene expression was lower by 0.9 fold compared with non-DM (p<0.05). By chi-square test, there was a positive correlation between TLR2 gene expression with fasting blood glucose (p=0.011, and a positive correlation between the abdominal circumference and TLR4 gene expression (p=0.011).</p><p><strong>Conclusion: </strong>Type-2 Diabetes mellitus patients in primary health care keep walking as their physical activity to maintain blood glucose. Patients need to do moderate to vigorous exercise regularly to reduce body fat percentage especially abdominal fat to reduce Toll-like receptor gene expression, so insulin resistance and blood glucose level might decline to normal.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"77 4","pages":"276-280"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0c/a1/medarch-77-276.PMC10591241.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50159644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aplasia Cutis Congenita of the Scalp with Bone Defect and Exposed Sagittal Sinus in Trisomy 13 Newborn - a Case Report.","authors":"Fisal Rashid AlMatrifi,&nbsp;Ahmad Ayed Al-Shammari,&nbsp;Raed Mohamed Al Nefily,&nbsp;Rawan Abdulrahman AlAnazi,&nbsp;Abdulrahman Hamed Abdulwahab,&nbsp;Ahmed Sabry Ammar","doi":"10.5455/medarh.2023.77.319-322","DOIUrl":"10.5455/medarh.2023.77.319-322","url":null,"abstract":"<p><strong>Background: </strong>Aplasia cutis congenita is a heterogeneous disorders group with a rare reported incident of 0.5 to 1 in 10,000 births. ACC can be associated with physical defects or syndrome that may help in diagnosis, prognosis and further evaluation of the patient. Trisomy 13 is one of the most common fetal life limiting diagnosis which is associated with ACC of membranous type scalp.</p><p><strong>Objective: </strong>In this article, we report cases of aplasia cutis congenita of the scalp with dura and bone defect and exposed sagittal sinus in newborn diagnosed to have trisomy 13. It emphasizes the importance of ACC associated syndrome which is having high mortality prior to surgical intervention.</p><p><strong>Case presentation: </strong>The patient was born at 35 weeks of gestation. Her physical examination revealed a newborn girl with dysmorphic facial features including widely separated eyes, downward slanting of the palpebral fissure, microphthalmia, retrognathia, and low seat ears. She had area of loss of scalp skin and skull bone with seen brain tissue and sagittal sinus were exposed that was measure 6 by 5 cm in size. Additionally, she had a clenched fist and overlapping fingers and rocker bottom feet. Laboratory investigations include basic labs and the TORCH screen was negative. On the 9th day of life, a chromosomal analysis showed a female karyotype with three copies of chromosome number 13 in all 20 metaphase cells counts.</p><p><strong>Conclusion: </strong>The patient was managed conservatively. However, a multidisciplinary team agreed on do not resuscitate with no further surgical intervention as survival rate of trisomy 13 is poor.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"77 4","pages":"319-322"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b7/84/medarch-77-319.PMC10591249.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50159652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adjuvant Intravesical Chemotherapy Versus Immunotherapy for All Risk Groups of Patients With Non-muscle Invasive Bladder Cancer.","authors":"Haris Djug, Sefik Hasukic, Samed Jagodic, Davor Ivanic","doi":"10.5455/medarh.2023.77.460-464","DOIUrl":"10.5455/medarh.2023.77.460-464","url":null,"abstract":"<p><strong>Background: </strong>The treatment strategy for non-muscle invasive bladder cancer (NMIBC) has not changed significantly over the past 30 years. Chemotherapeutic agents (mitomycin-C, epirubicin, etc.) and BCG (Bacillus Calmette-Guerin) immunotherapy are used as adjuvant intravesical therapy.</p><p><strong>Objective: </strong>To compare the difference between adjuvant chemotherapy and adjuvant immunotherapy in their efficacy of reducing the number of tumor recurrences.</p><p><strong>Methods: </strong>In this prospective clinical study, which included 99 patients with NMIBC from March 2018.-March 2023., we publish the results for all risk groups of patients treated with intravesical chemotherapy Epirubicin or with BCG immunotherapy, after TURBT (Trans urethral resection of bladder tumor) within 1 year. Patients were stratified into 2 groups. The first group was treated with Epirubicin (1 dose within 24 hours of surgery, then 6 weekly instillations and 3 maintenance doses), and the second group was treated with BCG (2-3 weeks after TURBT 6 weekly instillations, and 3 maintenance doses). The monitoring period was 24 months.</p><p><strong>Results: </strong>In patients treated with intravesical chemotherapy, recurrence occurred in 9 patients (17.64%), and in patients treated with BCG, recurrence occurred in 7 patients (14.58%). A similar incidence of disease recurrence was observed in both groups (p=0.787).</p><p><strong>Conclusion: </strong>The results of our study show a similar therapeutic response by risk groups of patients treated with chemotherapy and immunotherapy. Since BCG production will cease in the future, the task of urologists is to introduce intravesical chemotherapy into wider use and to modernize it as a safe and effective method of adjuvant treatment for non-muscle-invasive bladder cancer.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"77 6","pages":"460-464"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10834055/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139682172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Giant Sclerosing Hepatic Hemangioma Presenting as Bornman-Terblanche-Blumgart Syndrome: a Case Report and Review of the Literature.","authors":"Arwa H Ibrahim,&nbsp;Dhuha N Boumarah,&nbsp;Arwa A AlGhamdi,&nbsp;Shadi A Alshammary","doi":"10.5455/medarh.2023.77.314-318","DOIUrl":"10.5455/medarh.2023.77.314-318","url":null,"abstract":"<p><strong>Background: </strong>Hepatic hemangioma represents the most frequent benign tumor originating from the liver. When the tumor exceeds 10 cm, and in some studies 4 or 5 cm, it is considered giant, which accounts for 10% of all hemangiomas arising from the liver. Histologically, Sclerosing hepatic hemangioma, in particular, is an exceedingly rare subtype of hemangioma. Clinically Bornman-Terblanche-Blumgart syndrome is a very rare complication of hepatic hemangioma.</p><p><strong>Objective: </strong>The aim of this case presentation was to contribute to the literature by documenting a case of giant sclerosing hemangioma diagnosed in a 36-year-old female presenting with Bornman-Terblanche-Blumgart syndrome, along with a brief review of the literature.</p><p><strong>Case report: </strong>The current paper documents two rare clinical and histological features of hepatic hemangioma. Bornman-Terblanche-Blumgart syndrome is complicated a giant hepatic hemangioma found histologically to be sclerosing in nature. Knowledge about the uncommon complications of liver hemangioma permits the implementation of appropriate interventions in a timely manner and, in turn, can enhance the patient's quality of life and minimize rates of associated mortality.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"77 4","pages":"314-318"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0c/ca/medarch-77-314.PMC10591242.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50159641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe Traumatic Brain Injury Presenting with Wide Complex Tachycardia: a Case Report.","authors":"Mohannad Alghamdi,&nbsp;Mohammed Almulhim,&nbsp;Abdullah Bunaian,&nbsp;Emad Al-Osail,&nbsp;Abdullah Alhowaish,&nbsp;Marwah Alabdulmhsin,&nbsp;Abdulaziz Alhawas,&nbsp;Dunya Alfaraj","doi":"10.5455/medarh.2023.77.306-309","DOIUrl":"10.5455/medarh.2023.77.306-309","url":null,"abstract":"<p><strong>Background: </strong>Ventricular tachycardia (VT) is an abnormal heart rhythm that can lead to pump failure and hypoperfusion. Its causes, presentation, and treatment are well established in the literature. However, the VT treatment algorithm is based on non-traumatic patients. Due to different pathophysiology and presentation, treating VT in trauma patients should be different.</p><p><strong>Objective: </strong>The main purpose is to emphasize the approach to treating VT in severe head trauma patients.</p><p><strong>Case presentation: </strong>This case is a unique presentation of severe head trauma with a paucity of treatment approaches in the literature. In this article, we present a case of a middle-aged male patient presented to a level one trauma center with a history of falls from 2 stories height with a Glasgow Coma Scale (GCS) of 3/15. ATLS approach was followed in treating this patient, his rhythm strip showed a wide complex regular rhythm, likely representing a VT with a pulse. The patient was treated as unstable because of a decreased level of consciousness. A 100 J synchronized cardioversion was given without restoration of normal sinus rhythm, followed by Mannitol 1g/kg, treating the possibility of high intracranial pressure (ICP), after which his rhythm was restored to sinus.</p><p><strong>Conclusion: </strong>The restoration of sinus rhythm after treating the possibility of high ICP suggests that the cause of VT in this severe TBI patient was the high ICP.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"77 4","pages":"306-309"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e1/c5/medarch-77-306.PMC10591240.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50159645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}