Medical archives (Sarajevo, Bosnia and Herzegovina)最新文献

{"title":"Community-Based Cross-Sectional Assessment Survey On Herpes Zoster Vaccination Practices.","authors":"Nouf F Bin Rubaian, Nada Alghamdi, Nada Alquorain, Serene R Almuhaidib, Nouf A AlShamlan, Assim M AlAbdulKader, Moataza M Abdel Wahab, Malak A Al-Shammari","doi":"10.5455/medarh.2024.78.95-99","DOIUrl":"https://doi.org/10.5455/medarh.2024.78.95-99","url":null,"abstract":"<p><strong>Background: </strong>Herpes Zoster (HZ), also known as Shingles, is a commonly occurring infection especially among the elderly. It is due to the reactivation of the dormant virus in the sensory ends that were present since the primary infection with the virus.</p><p><strong>Objective: </strong>Our study aims at assessing the knowledge, attitudes practices beliefs and current barriers towards the Shingrix vaccine to fully understand where we stand and come up with proper recommendations to services these at-risk individuals and ultimately have a positive impact on the healthcare system.</p><p><strong>Methods: </strong>Questionnaire based cross sectional study using a translated version of a previously developed and tested questionnaire.</p><p><strong>Results: </strong>more than 8000 participants responded to the survey. The vast majority had chicken pox before and did hear about the vaccine from different sources. Most of the participants had minimal knowledge regarding the vaccine and were willing to take it regardless of some safety concerns.</p><p><strong>Conclusion: </strong>more efforts need to be conducted to enhance vaccine uptake in at risk populations in Saudi Arabia.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 2","pages":"95-99"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10983100/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140862776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CD56 Expression in Spleen Tissue Pathology and Its Implications in the Development of Type 1 Diabetes: Insights from Diabetic Rat Models.","authors":"Suha Khayri Ababneh, Osama Odat, Ali Ata Alsarhan, Jumanah D Al-Shawabkeh, Futoon Abedrabbu Al-Rawashde, Rawan Al-Jaloudi, Moath Alqaraleh, Nihad Al-Othman, Ahed J Alkhatib","doi":"10.5455/medarh.2024.78.274-278","DOIUrl":"10.5455/medarh.2024.78.274-278","url":null,"abstract":"<p><strong>Background: </strong>Type 1 diabetes (T1D) is an autoimmune disease characterized by the destruction of beta cells in the pancreas.</p><p><strong>Objective: </strong>This study's goals were to look at how much CD56 was expressed in the spleen tissue of rats with type 1 diabetes and compare it to rats that were not diabetic.</p><p><strong>Methods: </strong>The method used in this study was to give rats type 1 diabetes by giving them Alloxan (120 mg/kg). The rats had diabetes for one month. As soon as the experiment was over, all the animals were put down and prepared for normal biochemical, histology, and immunohistochemical tests.</p><p><strong>Results: </strong>The study results revealed that the biochemical findings including glucose, cholesterol, and triglycerides in diabetic group were more significantly higher than that in the control group. The spleen tissue of diabetic rats was more inflamed than that of the control group, as shown by histological results. CD56 expression was much lower in the rats of diabetic group compared to the rats in the control group.</p><p><strong>Conclusion: </strong>When looked at as a whole, CD56's role in diabetes seems to have been lost. This explains why people with type 1 diabetes have inflammatory problems.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 4","pages":"274-278"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11838832/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143470338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Salvaging From Limb Amputation in an Acute Complicated Type B Aortic Dissection Patient.","authors":"Pham Minh Tuan, Nguyen Ngoc Quang, Pham Manh Hung, Le Xuan Than","doi":"10.5455/medarh.2024.78.313-316","DOIUrl":"10.5455/medarh.2024.78.313-316","url":null,"abstract":"<p><strong>Background: </strong>Aortic dissection is a condition in which there is an intimal tear that allows the blood to pass through the tear and into the aortic media, splitting to a true lumen and a newly formed false lumen. It is associated with genetic disorders such as Marfan syndrome, Ehlers-Danlos syndrome, and Loeys-Dietz syndrome, or may result from cardiovascular risk factors including smoking, hypertension, and familial hyperlipidemia.</p><p><strong>Objective: </strong>The aim this article was to report a complicated Stanford B aortic dissection with acute limb ischemia and compartment syndrome, successfully managed with limb preservation and aortic repair.</p><p><strong>Methods: </strong>A 60s male patient with poorly controlled hypertension presented with severe chest pain radiating to the back and right leg ischemia, characterized by coldness, numbness, motor loss, and absent arterial pulses.</p><p><strong>Case presentation: </strong>The patient was treated with intensive medical management, including pain control, heart rate and blood pressure stabilization, while preparing for emergency intervention. A thoracic aortic endovascular stent-graft was placed to seal the entry tear and restore blood flow to the right lower limb. The intervention utilized a Relay thoracic stent-graft (32-28 mm diameter, 200 cm length, Bolton Medical), with access via the left common femoral artery Stanford Type B aortic dissection complicated by limb ischemia is a cardiovascular emergency requiring urgent intervention.</p><p><strong>Conclusion: </strong>Timely monitoring, insight consultation with orthopedic physician to understand the pathophysiology of acute compartment syndrome, the importance of early diagnosis and precise management of acute compartment syndrome following intervention are crucial to preserving the limb and ensuring the success of endovascular aortic repair.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 4","pages":"313-316"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11838834/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143470345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Dark Chocolate and Carrot Juice on Perceived Labor Pain During Stage 1 of Birth Delivery Among Primigravida: A Quasi-Experimental Study.","authors":"Fazdria Fazdria, Alchalidi Alchalidi, Abdurrahman Abdurrahman, Nora Veri, Lina Lina, Cut Mutiah, Yohanes Andy Rias","doi":"10.5455/medarh.2024.78.149-153","DOIUrl":"https://doi.org/10.5455/medarh.2024.78.149-153","url":null,"abstract":"<p><strong>Background: </strong>Dark chocolate and carrot juice may positively decline the pain. However, there is a lack evidence the impact of combination dark chocolate and carrot juice on labor pain during stage 1 of birth delivery among primigravida.</p><p><strong>Objective: </strong>This study aimed to examine the effectiveness of dark chocolate and carrot juice on perceived labor pain during stage 1 of birth delivery among primigravida.</p><p><strong>Methods: </strong>This was a quasi-experimental study with participants who received dark chocolate (n=30), carrot juice (n=30), and control group (n=30). Pain level was assessed by using the Numeric Pain Rating Scale (NPRS) before the intervention and at 30 hours after intervention. The Chi-square and one-way analysis of variance tests and general equational model were used.</p><p><strong>Results: </strong>Data were collected and analyzed before and after 60 minutes of intervention. Our results showed a significant interaction between the group and time, with both groups independently ameliorating labor pain.</p><p><strong>Conclusion: </strong>Dark chocolate and carrot juice therapies independently lowered pain labor in primigravida mothers, making them a viable treatment for advanced pain labor.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 2","pages":"149-153"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10983098/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140862118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the Anticancer Potential of Pasak Bumi (Eurycoma Longifolia Jack) Root Extract in Prostate Cancer Treatment.","authors":"Eka Yudha Rahman, Nia Kania, Hendra Sutapa, Athaya Febriantyo Purnomo, Roselina Panghiyangani, Nika Sterina Skripsiana","doi":"10.5455/medarh.2024.78.117-121","DOIUrl":"https://doi.org/10.5455/medarh.2024.78.117-121","url":null,"abstract":"<p><strong>Background: </strong>Prostate cancer remains a significant global health concern, necessitating the exploration of novel therapeutic avenues to enhance treatment efficacy and mitigate adverse effects. <b>Objective</b> This study delves into the potential anticancer properties of Pasak Bumi (Eurycoma longifolia Jack) root extract, a traditional Southeast Asian medicinal plant, against prostate cancer.</p><p><strong>Methods: </strong>The research employs a multifaceted approach, encompassing molecular and cellular analyses to unravel the intricate mechanisms underlying Pasak Bumi's effects on prostate cancer cells. Primary focus is given to the PTEN/P13k/Akt pathway, a critical regulator of cell survival and apoptosis. Various concentrations of Pasak Bumi root extract are applied to prostate cancer cell lines, and the impact on apoptosis, cell proliferation, and key molecular targets is assessed.</p><p><strong>Results: </strong>Preliminary findings reveal that Pasak Bumi root extract induces apoptosis in prostate cancer cells, evidenced by downstream molecular events associated with programmed cell death. The extract demonstrates concentration-dependent effects, with higher concentrations exhibiting more pronounced anticancer activity. Moreover, Pasak Bumi root extract appears to modulate the PTEN/P13k/Akt pathway, providing a potential mechanistic link to its anticancer effects. <b>Discussion:</b> The study's significance lies in its contribution to the evolving landscape of natural compounds as anticancer agents, particularly in the context of prostate cancer. Pasak Bumi's traditional use as a medicinal plant, coupled with emerging scientific evidence, underscores its potential translational value. The observed modulation of the PTEN/P13k/Akt pathway aligns with the current understanding of prostate cancer pathogenesis, offering a plausible explanation for Pasak Bumi's anticancer effects.</p><p><strong>Conclusion: </strong>This research sheds light on the promising anticancer potential of Pasak Bumi root extract against prostate cancer. Further exploration of its molecular interactions, synergy with conventional therapies, and efficacy at different stages of cancer progression is warranted. The findings present Pasak Bumi as a nature-inspired candidate for prostate cancer treatment, warranting continued investigation into its therapeutic applications. As the scientific community endeavors to enhance cancer treatment modalities, Pasak Bumi emerges as a captivating subject in the pursuit of effective and minimally invasive prostate cancer therapies.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 2","pages":"117-121"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10983097/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140862195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and Safety of Levetiracetam for Childhood Epilepsies.","authors":"Feriha Hadzagic Catibusic, Sajra Uzicanin, Emina Vukas Salihbegovic, Zinka Huseinbegovic","doi":"10.5455/medarh.2024.78.122-126","DOIUrl":"https://doi.org/10.5455/medarh.2024.78.122-126","url":null,"abstract":"<p><strong>Background: </strong>Levetiracetam (LEV) is a broad spectrum second-generation antiepileptic drug (AED).</p><p><strong>Objective: </strong>The objective of the study was to investigate the efficacy and safety of levetiracetam for childhood epilepsies.</p><p><strong>Methods: </strong>This is single, tertiary centre observational, prospective study, that included paediatric patients who were treated with levetiracetam at Paediatric hospital University Clinical Centre Sarajevo, during the period of 15 years (2008-2022). Inclusion criteria were: paediatric patients age > 1 month, diagnosed with epilepsy according to International League Against Epilepsy. After the introduction of levetiracetam, each patient has been followed up at least 12 months. According to the outcome the patients were divided into 5 groups: seizure reduction >50%, seizure reduction <50%, complete seizure freedom, the same number of seizures and increased number of seizures. From these groups two intergroups have been formed: responders (seizure reduction >50% and complete seizure freedom) and non-responders (seizure reduction <50%, the same number of seizures and increased number of seizures).</p><p><strong>Results: </strong>The study enrolled 259 patients (141 female and 118 male), with mean age 7 years (3,0-12.0). Comorbidities were present at 129/259 (49.8%) patients. After 12 months of treatment, 25/259 (9.7%) patients had seizure reduction >50%, 30/259 (11.6%) patients had seizure reduction <50%, 154/259 (56.5%) patients had achieved seizure freedom, 31/259 (12%) patients had same number of seizures, while 19/259 (7.3%) patients had increased number of seizures. Seizure frequency between responders and non-responders, before treatment and after 12 months of treatment was statistically significant (p<0.001).</p><p><strong>Discussion: </strong>Non responders had the best outcome with ditherapy (30/79; 38%), while responders had the best outcome with monotherapy (161/180;89.4%).</p><p><strong>Conclusion: </strong>Levetiracetam is efficient antiepileptic drug for different types of epilepsies in childhood, used as mono, di or polytherapy.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 2","pages":"122-126"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10983095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140862777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Level of Awareness of Certified Non-critical Care Physicians in Diagnosing, Managing, and Disposing Anaphylactic Cases.","authors":"Dalal Almarri, Fatimah Badghaish, Dalal Albaiji, Areen Alamri, Rawan Alghamdi, Rehab Alghamdi, Faisal Alkhadra, Nisreen Maghraby","doi":"10.5455/medarh.2024.78.44-50","DOIUrl":"10.5455/medarh.2024.78.44-50","url":null,"abstract":"<p><strong>Background: </strong>Anaphylaxis is known as an acute, severe hypersensitivity reaction that rapidly initiates after exposure to a triggering agent. It is a life-threatening condition, and early recognition and swift intervention are crucial to saving patients' lives. Objective: The objective of this study is to assess the ability of certified non-critical care physicians to recognize, manage, and dispose cases of anaphylaxis.</p><p><strong>Methods: </strong>A survey consisting of 19 questions was developed by expert emergency consultants to evaluate physicians' knowledge regarding the recognition, management, and disposition of anaphylactic episodes. Responses were collected through in-person surveys conducted with physicians from various specialties and varying clinical experience levels at a tertiary care center in the Eastern Province of Saudi Arabia.</p><p><strong>Results: </strong>In this cross-sectional study, a total of 173 physicians completed the survey, with 81.5% being consultants and 18.5% specialists. Only 5.2% correctly identified all three proposed anaphylaxis clinical scenarios, 16.8% identified two scenarios correctly, and 51.4% identified only one scenario. While 42.8% recognized the first-line management of anaphylaxis, only 24.3% and 24.9% knew the correct epinephrine dose and route, respectively. Regarding the disposition of patients experiencing an anaphylactic episode, 61.9% of responders opted to dispose the case to the emergency department.</p><p><strong>Conclusion: </strong>Our study reveals a knowledge gap among non-critical care physicians practicing in a tertiary care center concerning the identification and management of anaphylaxis. Raising awareness of this life-threatening condition is imperative to address this serious issue.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 1","pages":"44-50"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10928686/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140121703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Efficacy of Piascledine in Alleviating Symptoms and Its Impact on Blood Lipid Levels and body Mass Index in Patients with Knee Osteoarthritis.","authors":"Hoang Minh Phan, Cang Trung Huynh, Phu Van La, Khanh Hoang Pham, Phuong Minh Vo, Trang Huynh Vo","doi":"10.5455/medarh.2024.78.296-301","DOIUrl":"10.5455/medarh.2024.78.296-301","url":null,"abstract":"<p><strong>Background: </strong>Piascledine is a potential treatment for osteoarthritis; however, current evidence regarding its efficacy in patients with knee osteoarthritis remains limited.</p><p><strong>Objective: </strong>To evaluate the efficacy of Piascledine in improving symptoms and its impact on blood lipid levels and body mass index in patients with knee osteoarthritis.</p><p><strong>Methods: </strong>A randomized, controlled, single-blind clinical trial. The odd-numbered group was treated with Piascledine at a dose of 300mg/day, while the even-numbered group was treated with glucosamine sulfate at a dose of 1,500mg/day. Outcomes were assessed at 4 weeks and 8 weeks.</p><p><strong>Results: </strong>A total of 200 patients were included in the study, with a mean age of 58.5 ± 11.3 years, of whom 42.0% were male. Obesity (OR=2.83; 95% CI: 1.88-4.26; p<0.001) and hypertriglyceridemia (OR=2.07; 95% CI: 1.17-3.67; p<0.05) were identified as factors significantly increasing the risk of severe osteoarthritis. At 4 weeks and 8 weeks, the Piascledine group showed a reduction in VAS scores from 49.3 ± 19.6mm to 37.6 ± 14.2mm and 25.3 ± 10.2mm, respectively. At 4 weeks, the VAS and WOMAC scores showed greater improvement in the GCS group compared to the Piascledine group. However, at 8 weeks, there was no significant difference in efficacy between the two groups. Treatment with Piascledine slightly increased triglyceride levels from 2.3 ± 1.4mmol/L to 2.7 ± 1.4mmol/L. Side effects were observed in 16.0% of patients during treatment, with the most common being nausea (10.0%).</p><p><strong>Conclusion: </strong>The study indicates that obesity and hypertriglyceridemia are risk factors for severe knee osteoarthritis. Treatment with Piascledine improves symptoms and knee joint function, without impacting body mass index or lipid metabolism. The majority of side effects were mild and primarily gastrointestinal.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 4","pages":"296-301"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11838829/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143470328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Active Case Finding for Tuberculosis in Migrants: a Systematic Review.","authors":"Joko Sapto Pramono, A Ridwan, Ida Leida Maria, Aminudin Syam, Syamsiar S Russeng, Syamsuar, Andi Agus Mumang","doi":"10.5455/medarh.2024.78.60-64","DOIUrl":"10.5455/medarh.2024.78.60-64","url":null,"abstract":"<p><strong>Background: </strong>Active case finding (ACF) is an alternative strategy to accelerate the identification of TB cases among the migrant population.</p><p><strong>Objective: </strong>This study aimed to synthesize the evidence for the effectiveness of ACF TB in migrants.</p><p><strong>Methods: </strong>This study uses the PRISMA model as a method of searching for journal articles in the databases of Google Scholar, ProQuest, EBSCO, ScienceDirect, Elsevier, and PubMed, as well as other sources such as textbooks and reports from 2017 to 2021 with the keywords <i>\"tuberculosis\" AND \"active case finding\" AND \"migrant\"</i>. The search revealed 371 articles, of which 26 met the criteria for further discussion.</p><p><strong>Results: </strong>Most studies show that the TB incidence among migrants is higher than in the local population. Factors leading to increased cases include lack of knowledge about the symptoms, high mobilization, social isolation, economic problems, and medication adherence that impact an advanced stage. Furthermore, it is also influenced by the low quality of health services, including accessibility, health facilities, health workers, and information. Therefore, Active Case Finding (ACF) is more effective in identifying cases of TB in the risk groups. This was conducted on migrants with increased notifications followed up with treatment.</p><p><strong>Conclusion: </strong>ACF is effective approach in screening and diagnosing TB in the migrant group.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 1","pages":"60-64"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10928684/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140121649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk of Obstructive Sleep Apnea and its Relation to Cognitive Functions Among Saudi Older Adults.","authors":"Yousef D Alqurashi, Khalid AlHarkan, Adam Aldhawyan, Ahmed Bahamdan, Fajar A Aldulijan, Sarah I Alsamin, Jood K Alotaibi, Arwa Alomran, Feras A Al-Awad","doi":"10.5455/medarh.2024.78.51-54","DOIUrl":"10.5455/medarh.2024.78.51-54","url":null,"abstract":"<p><strong>Background: </strong>The association between obstructive sleep apnea (OSA) and cognitive decline among older adults is a still a topic of debate. Objective: The aim of this study was to determine the association between risk of OSA and cognitive function among Saudi older adults.</p><p><strong>Methods: </strong>This was a cross-sectional community-based study conducted between July and October 2022. Participants were recruited from gathering areas where older adults are likely attending such as district centers, waiting areas of shopping malls, and mosques. Questionnaires were completed using face-to-face interviews. The questionnaire included questions of sociodemographics, sleep pattern and health status. A validated Arabic version of Athens insomnia scale, STOP-BANG questionnaire, and St. Louis University mental status (SLUMS) questionnaire were used. A multi-Linear regression model was used to determine the association between cognitive functions and OSA.</p><p><strong>Results: </strong>A total of 343 participants were recruited in this study, of which 86% were male. The mean age was 65±9 years. 65% of participants with high risk of sleep apnea were diagnosed with either dementia or mild cognitive impairment (MCI). Most of the participants who were illiterate (83%) had dementia, while only 4% of participants with higher education had dementia.</p><p><strong>Conclusion: </strong>Dementia and mild cognitive impairment is prevalent among Saudi older adults with high risk of OSA. Clinicians and patients should be aware of the risk of developing dementia in patients with OSA, especially if remain untreated.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 1","pages":"51-54"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10928689/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140121706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}