Medical archives (Sarajevo, Bosnia and Herzegovina)最新文献

{"title":"The Perioperative Neonatal and Maternal Glycemic Response and APGAR Score During Elective Cesarean Section: Factors and Anesthetic Management.","authors":"Diab A Bani Hani, Omar F Altal, Ala A A Alhowary, Anas Alrusan, Rania Al-Bataieneh, Khayria Tahir, Shahed Shloul, Malak Issa, Ahmed Al Sharie","doi":"10.5455/medarh.2025.79.34-40","DOIUrl":"https://doi.org/10.5455/medarh.2025.79.34-40","url":null,"abstract":"<p><strong>Background: </strong>The type of anesthesia and intensity of pain experienced during surgery are linked to the body's stress response, as reflected in preoperative and postoperative glucose levels.</p><p><strong>Objective: </strong>This comparative study aims to assess the hyperglycemic stress response to cesarean sections performed under different types of anesthesia.</p><p><strong>Methods: </strong>This prospective study included 302 participants, divided into two groups: a general anesthesia group and a spinal anesthesia group. Our primary objective was to investigate the effects of general versus spinal anesthesia on pregnant women undergoing cesarean section. Secondarily, we aimed to assess the impact of other factors on the maternal and neonatal stress response during surgery.</p><p><strong>Results: </strong>Both groups exhibited a significant proportional increase in mean blood glucose levels after surgery. However, this increase was more pronounced in the general anesthesia group than in the spinal anesthesia group. Therefore, spinal anesthesia had a greater effect in attenuating the hyperglycemic response to surgery during cesarean section compared to general anesthesia. Maternal blood glucose levels were significantly associated with steroid injection, type of anesthesia, and gestational age. In contrast, neonatal blood glucose was significantly associated with gestational age, APGAR score, maternal steroid injection, type of anesthesia, maternal age, and both preoperative and postoperative maternal blood glucose levels.</p><p><strong>Conclusion: </strong>Spinal anesthesia was superior to general anesthesia in attenuating both maternal and neonatal hyperglycemic responses during the cesarean section. This highlights the significant impact of anesthesia type on maternal and neonatal well-being.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 1","pages":"34-40"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship Between Abnormal Morphokinetic Embryos, Genetic Testing Results, and Clinical Outcomes.","authors":"Diem Thi Yen, Nguyen Khang Son, Nguyen Thi Hue Giang, Le Thi Quyen, Doan Nhu Tho, Tran Thi Dieu Thuy, Nguyen Xuan Hoi","doi":"10.5455/medarh.2025.79.4-8","DOIUrl":"https://doi.org/10.5455/medarh.2025.79.4-8","url":null,"abstract":"<p><strong>Background: </strong>Embryo quality is a crucial factor in the success of in vitro fertilization (IVF). Morphokinetics, which refers to the timing and sequence of embryonic cell division and development, has gained attention as a potential indicator of embryo viability and genetic competence.</p><p><strong>Objective: </strong>This study evaluates the relationship between abnormal embryonic morphokinetics and genetic analysis results, and their impact on clinical outcomes in assisted reproductive technology (ART).</p><p><strong>Methods: </strong>Conducted at Duc Phuc Hospital with Hanoi Medical University from January to December 2023, the prospective study included 152 patients undergoing in-vitro fertilization (IVF). A total of 968 blastocysts were analyzed using preimplantation genetic testing for aneuploidy (PGT-A). Time-lapse monitoring assessed cell division milestones and abnormal morphokinetic patterns, including direct cleavage, reverse cleavage, multinucleation, and vacuole. Patients received a single euploid embryo transfer. Clinical outcomes were tracked to the live birth stage, analyzed using SPSS 20.0, with p-values < 0.05 considered significant.</p><p><strong>Results: </strong>Of 583 blastocysts, 294 (50.4%) showed abnormal cleavage patterns. The aneuploidy rate was higher in embryos with reverse cleavage (56.1%) and multinucleation (50%), while direct cleavage and vacuolization showed no significant correlation. Early blastocyst formation (≥100 hours) was linked to a higher aneuploidy rate (60.8%). Nonetheless, clinical outcomes, such as β-hCG positivity and live birth rates, were similar between abnormal and normal cleavage groups when euploid embryos were transferred.</p><p><strong>Conclusion: </strong>Abnormal morphokinetic patterns are linked to higher aneuploidy rates, but do not significantly affect clinical outcomes when euploid embryos are selected. Integrating genetic testing with morphokinetic assessment can optimize ART success rates.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 1","pages":"4-8"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Correlation Between Plasma Bilirubin Concentrations and Glomerular Filtration Rate and Creatinine in Type 2 Diabetes with Renal Damage.","authors":"Nguyen Tien Dung, Hoang Thi Ngoc Tram, Vu Thi Thu Hang, Pham Thi Thuy","doi":"10.5455/medarh.2025.79.52-55","DOIUrl":"https://doi.org/10.5455/medarh.2025.79.52-55","url":null,"abstract":"<p><strong>Background: </strong>Diabetic nephropathy is one of the causes of chronic kidney disease with a very complex mechanism, in which oxidative stress plays an important role and bilirubin acts as an effective antioxidant, protecting cells from damage caused by oxidative stress.</p><p><strong>Objective: </strong>The aim of the study was to investigate the relationship between plasma bilirubin concentration with glomerular filtration rate and creatinine in patients with type 2 diabetes with renal damage.</p><p><strong>Methods: </strong>Total amount of 60 patients with type 2 diabetes with renal damage. Study design was descriptive.</p><p><strong>Results: </strong>Mean age 64.1±4.76. The rate of decreased glomerular filtration rate was 86.7% and increased albuminuria accounted for 96.7%. The concentration of total bilirubin in plasma decreased correspondingly to the decrease in glomerular filtration rate. The concentration of total, free and conjugated bilirubin was negatively correlated with creatinine concentration (r=-0.48), (r=-0.37), (r=-0.34) and positively correlated with glomerular filtration rate (r=0.54), (r=0.45), (r=0.41) with p<0.05). The area under the curve (AUC) of total bilirubin concentration was 0.7, lower than the area under the curve (AUC) of creatinine concentration 0.8, uric acid 0.74.</p><p><strong>Conclusion: </strong>Plasma bilirubin concentration is inversely correlated with creatinine concentration and positively correlated with glomerular filtration rate.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 1","pages":"52-55"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045591/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144052556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinicopathological Analysis of Mediastinal Masses: a Single-Institute Experience.","authors":"Zeead M Alghamdi, Sharifah A Othman, Dhuha N Boumarah, Mohammed Sabry Abdelmotaleb, Farouk Alrashaid, Yasser Aljehani, Hatem Y Elbawab","doi":"10.5455/medarh.2025.79.15-19","DOIUrl":"https://doi.org/10.5455/medarh.2025.79.15-19","url":null,"abstract":"<p><strong>Background: </strong>The centrally located portion of the thoracic cavity is called the mediastinum and consists of several essential organs. In the presence of various outcomes and prognostic indicators of mediastinal masses, meticulous diagnosis of these masses is considered crucial.</p><p><strong>Objective: </strong>In this study, we analyzed all mediastinal masses observed clinically and pathologically at one institution over a period of ten years.</p><p><strong>Methods: </strong>This is a retrospective, single-institution review of 94 patients with mediastinal masses, drawing on existing data recorded by the hospital. The study was carried out at the King Fahd University Hospital, Khobar, Saudi Arabia. Data was collected from 2009 to 2019. Participants were all patients with malignant or benign mediastinal masses admitted to the hospital, or diagnosed incidentally to have mediastinal masses during investigations for other reasons.</p><p><strong>Results: </strong>The mean age for developing a mediastinal mass was 33.89 ± 18.91 years of age. Most of the patients (69.1%) were symptomatic at presentation. Overall, (49.23%) of patients who were symptomatic at diagnosis had a malignant mass. Concerning pathologic diagnosis and presentation of the patient (symptomatic versus asymptomatic), there was a significant positive relationship between pathologic diagnosis and symptoms with a P value of 0.020. In our study, only 5.15% of cases experienced recurrence.</p><p><strong>Conclusion: </strong>This study provides a great understanding of mediastinal tumor biology and the role of both radiotherapy and chemotherapy in increasing the survival rates of patients suffering from similar malignant conditions.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 1","pages":"15-19"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Thoracolumbar Pott's Disease in the Immunocompetent; Institutional Experience Over a Decade and Comprehensive Literature Review.","authors":"Yasser Aljehani, Naif ALkhaldi, Lama Althunayyan, Rahaf Alghamdi, Sadeem Aljamaan, Marwan Alwazzeh, Farouk Alreshaid","doi":"10.5455/medarh.2025.79.41-46","DOIUrl":"10.5455/medarh.2025.79.41-46","url":null,"abstract":"<p><strong>Background: </strong>The presentation of Pott's has a wide variation and an insidious onset, which makes timely accurate diagnosis quite challenging.</p><p><strong>Objective: </strong>To review Pott's cases to enhance the disease management and fill the literature gap regarding the approach to Pott's disease.</p><p><strong>Methods: </strong>A descriptive observational retrospective hospital-based study conducted from 2007 to 2022 at KFHU. 346 patients who were diagnosed with TB were reviewed thoroughly. Only 13 cases were labeled as Pott's disease based on imaging or microbiology testing and hence were included in this study, and other TB pulmonary and extrapulmonary cases were excluded.</p><p><strong>Results: </strong>In our analysis of 13 cases of Pott's disease, we observed a significant male predominance (69.23%) and diverse symptoms, with back pain (69.2%) being most prevalent among our patients. Lumbar involvement was the most frequently observed site (38.4%), and diagnoses were made through microbiology (69.2%) or clinical/radiological means (30.8%). Acid-fast bacilli (AFB) culture testing exhibited a positivity rate of 61.5%, while TB-PCR showed positive results in 57.1%. Imaging studies revealed vertebral lesions (90.9% CT, 81.8% MRI), abscesses (54.5% CT, 81.8% MRI), and spondylodiscitis (18.2% CT, 54.5% MRI). Treatment, administered in 92.3% of cases, involved the use of Isoniazid, Rifampicin, and Ethambutol. Surgical interventions, though less frequent, encompassed various procedures. Outcomes demonstrated a notable high cure rate of 84.9%, with a 15.4% incidence of cases experiencing loss of follow-up.</p><p><strong>Conclusion: </strong>The high cure rate of 84.9% accentuates the effectiveness of early diagnosis and comprehensive treatment strategies that combine medical and surgical interventions when necessary.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 1","pages":"41-46"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045595/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Body Dysmorphia in Polycystic Ovary Syndrome (PCOS) Patients.","authors":"Fatima Sabri Al-Ali, Mohammed Al-Shujaie, John Flood","doi":"10.5455/medarh.2025.79.27-33","DOIUrl":"https://doi.org/10.5455/medarh.2025.79.27-33","url":null,"abstract":"<p><strong>Background: </strong>Polycystic ovary syndrome (PCOS), a significant hormonal disorder that primarily affects young women, has a substantial impact on both their health-related quality of life and their mental well-being.</p><p><strong>Objective: </strong>To assess the prevalence and patterns of body dysmorphia in polycystic ovary syndrome (PCOS) patients in Kingdom of Bahrain and to reach a consensus regarding the relationship between body dysmorphia and PCOS.</p><p><strong>Methods: </strong>There were 132 participants involved in the study: 66 were control cases, 66 were PCOS cases. Each was given a survey form. The scoring was based on the Głębocka's self-perception scale and modified Ferriman-Gallwey hirsutism scale were used to assess about own perception to appearance, and pressure to change body shape.</p><p><strong>Results: </strong>Most of the PCOS patients in the Kingdom of Bahrain who are above 30 years old experienced body dysmorphia along with other physical changes in appearance and psychological disorders such as social anxiety and depression. About 86% of them have hirsutism which significantly affects their self-esteem and self-confidence within themselves. However, the average hair distribution volume ranges only from 1.82 to 2.53 in the different parts of the body.</p><p><strong>Conclusion: </strong>Body dysmorphia is prevalent in patients diagnosed with PCOS. It is important to understand that these manifestations of PCOS in women significantly impact their quality of life..</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 1","pages":"27-33"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045581/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"C-reactive Protein Levels in Prediction of the Development or the Progression of Agerelated Macular Degeneration in Patients Examined at Tuzla Canton.","authors":"Alma Cickusic, Suzana Pavljasevic, Vahid Jusufovic, Sanja Sefic-Kasumovic, Adisa Pilavdzic Hasic, Meliha Halilbasic","doi":"10.5455/medarh.2025.79.47-51","DOIUrl":"https://doi.org/10.5455/medarh.2025.79.47-51","url":null,"abstract":"<p><strong>Background: </strong>Age-related macular degeneration (ARMD) is a chronic, incurable, progressive, multifactorial, neurodegenerative disease, which is one of the leading causes of visual impairment, among individuals above 60 years of age in developed countries. Over the past decades, the role of inflammation and CRP in the pathogenesis of ARMD has been investigated.</p><p><strong>Objective: </strong>The study aimed to investigate the association between inflammation or CRP levels in prediction the development or the progression of ARMD.</p><p><strong>Methods: </strong>This retrospective-prospective, case-control study, was conducted at the Clinic for Eye Diseases, University Clinical Center Tuzla, from 2020. to 2024. Two group of participants were included in this study. The first group (n=100 patients) consisted of patients diagnosed with different stages of ARMD, and second, control group (n=100 patients) consisted of patients without ARMD. The study included subjects of both sexes, divided into three age categories (≤55; 56-66; ≥67 years). Detailed ocular and systemic evaluations were performed, including fundus examination and OCT angiography. A 5mL sample of venous blood was colected to determine serum CRP levels, for the both group of patients, using latex immunoassay method. Statistical analysis, including Student's t-test, Chi square test and posthoc (Turkey) tests, was conducted using SPSS 26 for Windows, with p<0,05 considered significant.</p><p><strong>Results: </strong>Out of 100 patients, 34 were having early, 18 intermediate and 48 were having advanced stages of ARMD. The mean serum CRP levels in the ARMD group (8.39±27.22mg/L) were significantly higher compared to the control group, (2.52±5.35mg/L), p=0,000. Also, serum CRP values by age category, between ARMD subjects and the control group, showed statistically significant differences in all age groups: ≤55 p=0.032; 56-66 p=0.019; ≥67 p=0.000. The mean serum CRP levels was 6.6±6.9 mg/L, 10±13.3 mg/L and 16±22.7 mg/L, in early, intermediate and advanced ARMD, respectively. Comparing these CRP values and different stages of ARMD, there were found statistically significant differences between the three stages. Furthermore, these results showed that mean CRP values increase with disease severity.</p><p><strong>Conclusion: </strong>Based on the obtained results serum CRP levels are significant risk factor in predicting the development and the progression of ARMD. Also, these results emphasize the role of systemic inflammation in the development and progression of ARMD.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 1","pages":"47-51"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144015480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sympathetic Ophthalmia After Complicated Cataract Surgery.","authors":"Nguyen Thanh Nam, Nguyen Quynh Anh","doi":"10.5455/medarh.2025.79.64-66","DOIUrl":"10.5455/medarh.2025.79.64-66","url":null,"abstract":"<p><strong>Background: </strong>Sympathetic ophthalmia (SO) is a bilateral, diffuse granulomatous panuveitis that can occur after a penetrating trauma or intraocular surgery. The time from ocular injury to the onset of sympathetic ophthalmia varies greatly, ranging from several days to decades.</p><p><strong>Objective: </strong>We report on the diagnostic dilemma and clinical outcome of patient with sympathetic ophthalmia within 2 weeks of cataract surgery.</p><p><strong>Case presentation: </strong>A patient underwent left eye cataract surgery that was complicated by postoperative iris prolapse through the corneal wound. The wound was sutures with iris still entrapped, and he presented to our clinic 1 week later with bilateral vision loss and panuveitis. After workup for other inflammatory or infectious causes, sympathetic ophthalmia was diagnosed, and the patient was treated with topical and systemic corticosteroids. One month later, visual acuity improved markedly in both eyes, and inflammatory symptoms and findings resolved. Sympathetic ophthalmia may occur soon after cataract surgery and can be confused with infectious endophthalmitis, which must be considered.</p><p><strong>Conclusion: </strong>Prompt diagnosis and institution of corticosteroid therapy is essential and may result in significant visual improvement in both eyes.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 1","pages":"64-66"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045593/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Challenges of Tuberculous Meningitis Initially Presenting as Otomastoiditis.","authors":"Hung Quang Nguyen, Hoa Hong Thi Doan, Long Hoang Vo","doi":"10.5455/medarh.2025.79.71-77","DOIUrl":"10.5455/medarh.2025.79.71-77","url":null,"abstract":"<p><strong>Background: </strong>Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), remains a major global health problem, with one-third of the world's population infected.</p><p><strong>Objective: </strong>This report presents five cases of tuberculous meningitis with a particular emphasis on the symptoms and signs of otitis media that, in various combinations, should raise suspicion for tuberculous meningitis.</p><p><strong>Case presentation: </strong>These cases underscore the diagnostic challenges and clinical complexities associated with tuberculous otitis media, particularly when there is concurrent involvement of the central nervous system. It is crucial for physicians to maintain a high index of suspicion for tuberculosis in patients exhibiting chronic otorrhea that does not respond to conventional treatments, especially in endemic regions or in the presence of systemic symptoms. The use of advanced diagnostic tools and a multidisciplinary approach is essential for achieving timely diagnosis and effective management. Early initiation of antituberculous therapy, coupled with surgical interventions when warranted, can lead to favorable clinical outcomes. However, it is important to note that some patients may experience long-term sequelae, which highlights the necessity for prompt diagnosis and treatment to improve prognosis in those presenting with otitis media.</p><p><strong>Conclusion: </strong>The findings of this case series contribute to a better understanding of the relationship between otitis media and tuberculous meningitis, advocating for increased awareness among healthcare providers to facilitate early recognition and intervention.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 1","pages":"71-77"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effects of Date Consumption on Labor and Vaginal Birth.","authors":"Mohammad Abou El-Ardat, Zarema Obradovic, Dzenana Saldo, Minela Velagic, Aida Omeragic, Nedim Galijasevic","doi":"10.5455/medarh.2025.79.56-60","DOIUrl":"https://doi.org/10.5455/medarh.2025.79.56-60","url":null,"abstract":"<p><strong>Background: </strong>Date palm fruits (Phoenix dactylifera L.) are a widely available product that contains numerous macronutrients including a high sugar content. Research has shown that date fruit extracts possess antibacterial and antifungal properties, as well as antimutagenic and antiatherogenic effects. Date fruit can also have a beneficial effect on the female reproductive system. Several studies have examined the impact of date consumption during pregnancy on the outcome of labor, providing useful results.</p><p><strong>Objective: </strong>This study aims to determine the effects of date fruit consumption on the onset and progression of labor.</p><p><strong>Methods: </strong>The study included 120 pregnant women who were pregnant at GAK Sarajevo, in the period from 01.01. 2020 to 31.12. 2020. The patients were divided into two groups, the first group of 60 patients who consumed 6 dates during the last four weeks of pregnancy, and the second group of 60 patients who did not consume dates during pregnancy.</p><p><strong>Results: </strong>There was a significant positive effect of consuming date fruits on maternal outcomes in the first and third stages of labor. The group of pregnant women who consumed dates had a shortened latent phase of labor, which meant that their cervix reached maximum dilation (10 cm) faster. Pregnant women in this group gave birth 8.5 hours faster than pregnant women who did not consume dates, in whom labor lasted about 15 hours. Of the 60 pregnant women in the first group, 60% had a spontaneous natural birth, and only 40% of the patients received oxytocin, because dates enhance the effect of oxytocin, which is responsible for uterine contractions.</p><p><strong>Conclusion: </strong>This study showed a promising effect of consuming date fruits on the duration of the stages of labor. Saturated and unsaturated fatty acids found in dates stimulate the production of prostaglandins, which are necessary for labor. Dates are also rich in folic acid, vitamin K, iron, potassium, and magnesium.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 1","pages":"56-60"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}