Medical archives (Sarajevo, Bosnia and Herzegovina)最新文献

{"title":"Objective Assessment of Combined Orbital Fat Repositioning and Fat Grafting in Upper Eyelid Hollowing.","authors":"Le Huu Dien, Hoang Tuan Anh, Vu Ngoc Lam, Vu Van Duc, Tran Hong Nguyen, Duong Nguyen Viet Anh, Nguyen Thi Hong Van, Tran Thiet Son","doi":"10.5455/medarh.2026.80.57-62","DOIUrl":"10.5455/medarh.2026.80.57-62","url":null,"abstract":"<p><strong>Background: </strong>Upper eyelid hollowing is a common manifestation of periorbital aging caused by soft-tissue atrophy and loss of orbital fat volume. Although various corrective techniques have been described, outcome assessment remains largely subjective. High-resolution ultrasonography may provide an objective and quantitative method for evaluating postoperative soft-tissue changes.</p><p><strong>Objective: </strong>The present study aimed to evaluate the effectiveness and stability of combined orbital fat repositioning and microfragmented autologous fat grafting for the correction of moderate upper eyelid hollowing, using high-resolution ultrasonography as an objective assessment tool.</p><p><strong>Methods: </strong>A prospective study was conducted in 35 female patients (70 upper eyelids), aged 40-65 years, with moderate upper eyelid hollowing (Park grade II). All patients underwent combined orbital fat pad repositioning with supplemental microfragmented autologous fat grafting. High-resolution ultrasonography was performed preoperatively and at 1, 3, and 6 months postoperatively to measure the space anterior to the upper eyelid skin (D1) and upper eyelid thickness (D2). Clinical outcomes and patient satisfaction were also evaluated.</p><p><strong>Results: </strong>he mean preoperative hollowing depth was 5.88 ± 0.85 mm, and the mean grafted fat volume was 1.09 ± 0.29 mL. Postoperative ultrasonography demonstrated a significant decrease in D1 and a significant increase in D2 at all postoperative time points compared with baseline (all p < 0.05). No statistically significant differences were observed between the 3- and 6-month follow-up periods (p > 0.05), indicating stabilization of outcomes after 3 months. Overall patient satisfaction was 97.14%. No major complications were observed.</p><p><strong>Conclusion: </strong>Combined orbital fat repositioning and microfragmented autologous fat grafting is a safe and effective technique for correcting moderate upper eyelid hollowing. High-resolution ultrasonography provides an objective, reproducible, and clinically applicable method for postoperative outcome assessment.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"80 1","pages":"57-62"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13049471/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147625398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Duodenal Diverticulitis as a Cause of Acute Severe Pancreatitis In the Patient With Clinical Obesity - a Case Report.","authors":"Dzenita Salihefendic, Ivan Vukoja","doi":"10.5455/medarh.2026.80.89-93","DOIUrl":"10.5455/medarh.2026.80.89-93","url":null,"abstract":"<p><strong>Background: </strong>Diverticula of the gastrointestinal tract are common in older adults, most often affecting the colon. While typically asymptomatic, acute diverticulitis represents the most frequent complication and may lead to severe outcomes, including perforation, abscess formation, and diffuse peritonitis. Duodenal diverticula on the other hand is a rare clinical entity, and is frequently detected incidentally during proximal endoscopy. While most cases are asymptomatic, inflammation of periampullary duodenal diverticula may result in serious complications. Acute pancreatitis secondary to duodenal diverticulitis is exceedingly rare and has been described almost exclusively in isolated case reports. Clinical obesity, particularly increased visceral adiposity, has been associated with more severe inflammatory responses in complicated diverticular disease and may influence disease progression and outcomes.</p><p><strong>Objective: </strong>The aim of this article was to present a case of severe acute pancreatitis with peripancreatic fat necrosis caused by acute duodenal diverticulitis in a patient with clinical obesity.</p><p><strong>Case presentation: </strong>A patient presented with diffuse abdominal pain and was diagnosed with severe acute pancreatitis based on laboratory findings and radiological imaging. Comprehensive diagnostic evaluation, including radiological studies, proximal endoscopy, and endoscopic ultrasound (EUS), excluded common etiology. Further assessment identified a markedly enlarged periampullary duodenal diverticulum as the most likely trigger, associated with peripancreatic visceral fat necrosis and with signs of multiorgan dysfunction. Subsequent anthropometric and body composition assessment confirmed clinical obesity with increased visceral fat area, which was considered a contributing factor to disease severity. Targeted pharmacological therapy combined with individualized nutritional intervention resulted in complete clinical remission.</p><p><strong>Conclusion: </strong>Complicated diverticular disease has been shown to be associated with obesity and increased visceral adipose tissue. Periampullary duodenal diverticulitis complicated by peripancreatic fat necrosis in patients with clinical obesity and increased visceral fat area is rarely described in the literature. Appropriate pharmacological treatment combined with a targeted dietary regimen aimed at reducing visceral adiposity may result in complete remission of severe acute pancreatitis. In patients with acute pancreatitis of unknown etiology and concomitant clinical obesity, duodenal diverticulitis and peripancreatic fat necrosis should be considered as potential underlying causes.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"80 1","pages":"89-93"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13049469/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147625381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"80th Anniversary of the Establishment of the \"Medical Archives\" Journal (1947-2026).","authors":"Izet Masic","doi":"10.5455/medarh.2026.80.4-20","DOIUrl":"10.5455/medarh.2026.80.4-20","url":null,"abstract":"<p><p>This year the journal \"Medical Archives\" celebrates 80th anniversary of the establishiment (1947-2026). With the name \"Medicinski Arhiv\" this journal was founded in the year 1947 as official journal of the Society of physicians of Bosnia and Herzegovina (B&H). The first Editorial board was consisted of professors of the Faculty of Medicine of the University in Sarajevo opened in November 16th 1947: Vladimir Čavka, Blagoje Kovačević, Bogdan Zimonjić and Ibro Brkić. \"Medical Archives\" journal was a key milestone that helped in education of all academic and professional staff that became the foundation of Bosnian and Herzegovinian medicine, as a science and health care as a profession. The oldest medical journal in B&H was \"Jahrbuch des Bosnisch-Herzegowinischen Landesspitales in Sarajevo\" (\"Annual of the National Hospital in Sarajevo\") which was established in 1897 and printed in German language in the period from 1897 until 1900. From the year 1950 \"Medicinski Arhiv\" was included in the most influential and important index database MEDLINE, as one of oldest medical journals in Souut-Eastern Europe. The first aim of journal was to give a opportunity to young researchers from B&H to present their scientific and research work to wider community. The tradition of publishing of \"Medical Archives\" as the most recognizable journal in B&H, was kept by Editor of Professor Izet Masic in 1993 who in extraordinary and difficult occasions (during wartime in BiH from 1992 until 1995) re-established journal and continued printing of the war issues. Hopefully the MEDLINE did not stop to continue receiving \"Medicinski arhiv\" journal and did not stop accept of published articles of \"Medicinski Arhiv\" in Medline/PubMed, SCOPUS, EMBASE, HINARI, EBSCO, and a lot of other indexed databases. From the year 2013 articles published in \"Medical Archives\" were included in PubMed Central with full papers (in extenso). Today \"Medical Archives\" belong to the most cited journals in former Yugoslavia countries with h-Index 38 in SCImago rank, it means 38 published papers in \"Medical Archives\" were cited 38 times in other indexed scientific journals worldwide, with SJR 0.33 and Q3 in the year 2024.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"80 1","pages":"4-20"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13049472/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147625320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Borrelia Burgdorferi in the Etiology of Chronic Urticaria.","authors":"Sajma Krkic-Dautovic","doi":"10.5455/medarh.2026.80.40-45","DOIUrl":"10.5455/medarh.2026.80.40-45","url":null,"abstract":"<p><strong>Background: </strong>Lyme borreliosis/European borreliosis (LB/EB) is a multisystemic infection caused by the bacterium <i>Borrelia burgdorferi</i>, which is transmitted to humans by the bite of ticks and other hematophagous insects. Transmitted borrelia can occupy any organ where it causes a silent inflammation, which in sensitive persons is intermittently repeated chronically.</p><p><strong>Objective: </strong>The aim of this paper was to determine how much <i>Borrelia burgdorferii</i> participates in the occurrence of chronic urticaria in children and adults.</p><p><strong>Methods: </strong>In the 13-year period from January 1, 2013 to December 31, 2025, a study of all manifestations of Lyme borreliosis was conducted on a sample of 1,059 patients, treated and monitored in the Private practice of an infectious disease specialist. The research was retrospective-prospective, descriptive, clinical and analytical. It was carried out in three phases: the first retrospective phase and the second two prospective phases. The diagnosis of LB was established on the basis of anamnestic-epidemiological data, clinical picture, clinical findings of new borreliosis markers and performed examinations. Serological confirmation of borreliosis was done using ELISA, WB and Immunoblot methods, as well as the ex-yuvantibus method, and in the last six months of 2025, additionally, the finding of bacteria Borreliosis in a dark field with a light microscope.</p><p><strong>Results: </strong>The results showed that 92.1% of the patients in the study group had intermittent migratory redness with itching. In the majority of patients, redness was without exudation or with little or no exudation. In 4.8% of patients, typical urticarial changes were found that occurred occasionally or daily. In all subjects, we serologically confirmed the presence of Borrelia burgdorferi. All patients had intermittent itching of the skin, which lasted for years.</p><p><strong>Conclusion: </strong>Based on the results, it can be concluded that <i>Borrelia burgdorfrii</i> is one of the most important factors in the development of chronic urticaria in monitored patients with 96.9%. Due to its persistence in the macroorganism, it causes reduced tolerance to food. Only 3.1% of cases of urticaria are caused by some other factors. In all cases of chronic urticaria, new clinical markers should be sought on the patients' skin. Serologically look for antibodies to Borrelia protein sequences in an immunoblot. In the active phase, look for Borrelia with a light microscope in the dark field. Administer antibiotic therapy together with antihistamines. Exclude food to which the intolerance test confirmed hypersensitivity greater than \"2\".</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"80 1","pages":"40-45"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13049474/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147624914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Analysis of Surgical Outcomes Following Duhamel, Soave, and Transanal Endorectal Pull-through Techniques in Hirschsprung's Disease.","authors":"Iqbal Pahlevi Adeputra Nasution, Muhammad Al Anas","doi":"10.5455/medarh.2025.79.386-389","DOIUrl":"10.5455/medarh.2025.79.386-389","url":null,"abstract":"<p><strong>Background: </strong>Hirschsprung's disease (HD) is a congenital condition marked by the absence of ganglion cells in the distal bowel, leading to chronic functional obstruction. Surgical management involves resection of the aganglionic segment and reconstruction using ganglionated bowel. Among the commonly performed procedures - Duhamel, Soave, and transanal endorectal pull-through (TAEP) - complications such as obstruction, enterocolitis, and stricture can lead to reoperation. <b>Objective:</b> This study aims to compare postoperative complications requiring reoperation following Duhamel, Soave, and TAEP procedures in patients with HD treated at Pirngadi General Hospital between 2014 and 2022.</p><p><strong>Methods: </strong>A retrospective review was conducted of 58 pediatric patients diagnosed with HD who underwent definitive pull-through procedures. Clinical data were extracted from electronic medical records, focusing on demographics, surgical technique, complications, and need for reintervention. Patients requiring a second surgery due to severe constipation or obstruction were further evaluated. <b>Results:</b> Of the 58 patients (64% male, 36% female), 30 underwent Duhamel (51.8%), 16 Soave (27.5%), and 12 TAEP (20.6%). Eight patients (13.7%) required reoperation: 2 (25%) from the Duhamel group, 5 (62.5%) from Soave, and 1 (12.5%) from TAEP. The mean age at initial surgery was 10.25 ± 7.59 months. Stricture (75%) and enterocolitis (37.5%) were the most frequent complications. Management included dilatation, septum resection, colostomy, and revision pull-through procedures.</p><p><strong>Conclusion: </strong>The Soave procedure was associated with a higher rate of reoperation. Tailored surgical selection and close postoperative monitoring are essential to improve long-term outcomes in HD.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 5","pages":"386-389"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12634088/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145590655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rheumatoid Arthritis and Atrial Fibrillation: a Complex Cardiovascular Intersection - Insights from a Retrospective Cohort Study.","authors":"Qusai Alqudah, Ahmad Alomari, Moh'd Daise, Ali Awad, Laith Rhabneh, Osama Obeidat, Omar Obeidat, Samar Alomari, Safwan Alomari","doi":"10.5455/medarh.2025.79.127-134","DOIUrl":"10.5455/medarh.2025.79.127-134","url":null,"abstract":"<p><strong>Background: </strong>Rheumatoid arthritis (RA) is associated with an increased risk of cardiovascular disease (CVD) and atrial fibrillation (AF), yet data on the clinical outcomes and management of AF in RA patients remain limited.</p><p><strong>Objective: </strong>This study aimed to evaluate the impact of RA on AF-related outcomes and treatment strategies.</p><p><strong>Methods: </strong>We conducted a retrospective cohort study using the TriNetX US collaborative network database, including adult patients diagnosed with AF between 2015 and 2025. Patients were divided into two cohorts based on the presence or absence of RA. Propensity score matching was performed to balance baseline characteristics.</p><p><strong>Results: </strong>A total of 33,922 RA-AF patients and 33,922 non-RA AF patients were analyzed after matching. RA-AF patients exhibited a significantly higher risk of all-cause mortality (24.5% vs. 21.0%, OR: 1.216, p<0.001) and hospitalization or emergency department visits (72.2% vs. 69.2%, OR: 1.153, p<0.001). Additionally, RA-AF patients had a higher incidence of ischemic stroke or transient ischemic attack (13.2% vs. 11.4%, OR: 1.180, p<0.001) and composite hemorrhagic events (14.4% vs. 10.6%, OR: 1.411, p<0.001). Notably, AF with rapid ventricular response (RVR) was more common in RA-AF patients (36.1% vs. 33.5%, OR: 1.122, p<0.001). Despite the elevated thromboembolic risk, RA-AF patients demonstrated lower utilization of anticoagulation (46.9% vs. 49.4%, OR: 0.905, p<0.001) and a preference for rate control over rhythm control strategies.</p><p><strong>Conclusion: </strong>RA-AF patients experience higher mortality, increased stroke and hemorrhagic risk, and more frequent hospitalizations compared to non-RA AF patients. Despite these risks, anticoagulation underutilization remains a concern.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 2","pages":"127-134"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12269761/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144677069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between CTLA4 Level and Obesity, Dyslipidemia, and Type 2 Diabetes Mellitus.","authors":"Dharma Lindarto, Darmadi Darmadi","doi":"10.5455/medarh.2025.79.117-121","DOIUrl":"10.5455/medarh.2025.79.117-121","url":null,"abstract":"<p><strong>Background: </strong>Obesity and Type 2 diabetes mellitus (T2DM) are growing public health concerns in Southeast Asia, including Indonesia. Obesity promotes insulin resistance and metabolic irregularities, increasing the risk for T2DM. CTLA-4, an immune checkpoint receptor, plays a role in immune regulation, but its involvement in obesity, dyslipidemia, and T2DM remains unclear.</p><p><strong>Objective: </strong>The aim of this study was to evaluate the association between CTLA-4 levels and obesity, dyslipidemia, and T2DM.</p><p><strong>Methods: </strong>A cross-sectional study was conducted at Universitas Sumatera Utara Hospital and affiliated hospitals, including 100 adult participants from the endocrine clinic. Participants with coronary heart disease, kidney issues, heart problems, and cancers were excluded. Fasting blood glucose, A1C levels, LDL cholesterol, triglycerides, and CTLA-4 expression were measured. BMI was calculated from age, gender, height, and weight data. Statistical analysis was performed using SPSS 26.0, applying the Mann-Whitney U-test and Spearman correlation for variable relationships. Statistical significance was set at p < 0.05. <b>Result:</b> Among 100 participants, 36% were obese, 42% had dyslipidemia, and 31% had T2DM. The median CTLA-4 serum level was 93.3 pg/mL (range 36-264). CTLA-4 levels were significantly lower in obese individuals (67.2 pg/mL) compared to non-obese individuals (106.8 pg/mL, p = 0.019). No significant differences in CTLA-4 levels were found for dyslipidemia (p = 0.839) or T2DM (p = 0.351). A significant negative correlation was found between CTLA-4 levels and BMI (r = -0.329, p = 0.001).</p><p><strong>Conclusion: </strong>CTLA-4 levels negatively correlate with BMI, indicating its potential involvement in obesity-related metabolic changes. No significant link was found with dyslipidemia or T2DM, warranting further research.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 2","pages":"117-121"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12269770/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144677103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complications and Outcome in Patients With Hydrocephalus Who Have Had a Ventriculoperitoneal Shunt Implanted.","authors":"Adnan Dostovic, Mirza Moranjkic, Kenan Galijasevic, Adnan Mujezinovic, Denisa Salihovic, Suljo Kunic","doi":"10.5455/medarh.2025.79.122-126","DOIUrl":"10.5455/medarh.2025.79.122-126","url":null,"abstract":"<p><strong>Background: </strong>Hydrocephalus is the accumulation of cerebrospinal fluid in the ventricles of the brain. Ventriculoperitoneal shunt placement is one of the most commonly performed neurosurgical procedures and is necessary for the treatment of most forms of hydrocephalus.</p><p><strong>Objective: </strong>The aim of the study was to determine demographic indicators, comorbidities, complications and outcome of patients with hydrocephalus after ventriculoperitoneal shunt implantation.</p><p><strong>Methods: </strong>This is a retrospective study. Data on the subjects' age, gender, symptoms, degree of disability, complications, comorbidities and outcome after ventriculoperitoneal shunt implantation were recorded. All patients were clinically examined by neurologists and neurosurgeons and diagnosed through unified and standardized algorithms according to established guidelines for hydrocephalus. Cognitive functionality was assessed according to the Mini Mental State Test. Urinary incontinence was assessed based on patients' subjective feelings. Data on comorbidities and complications were collected from the patients' medical records. The degree of disability was assessed using the modified Rankin scale.</p><p><strong>Results: </strong>The average age of the subjects was 58.7 years, and the highest frequency of subjects was in the age group over 61 years (62.2%). There was no statistically significant difference in age in men (X=54.69, SD=18.77), or women (X=60.88, SD=19.96); t (35)=0.8, p=0.3. A statistically significant number of patients with hydrocephalus had a lower degree of disability after ventriculoperitoneal shunt implantation (p<0.05). Hypertension was the most common comorbidity with hydrocephalus (35.1%). Pneumonia was the most common general complication in patients with hydrocephalus (8.1%). Females had a statistically significantly worse survival (p=0.01). There was no statistically significant difference in the outcome of hydrocephalus patients in relation to age groups, comorbidities, general and complications after ventriculoperitoneal shunt implantation (p>0.05).</p><p><strong>Conclusion: </strong>Patients with hydrocephalus after ventriculoperitoneal shunt implantation have a lower degree of disability, and female patients have statistically significantly worse survival. Hypertension is the most common comorbidity, and pneumonia the most common complication in patients with hydrocephalus. There is no statistically significant difference in the outcome of hydrocephalus patients in relation to age groups, comorbidities, general and complications after ventriculoperitoneal shunt implantation.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 2","pages":"122-126"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12269767/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144677105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic Impact of Nasal Irrigation and Health Education in Reducing Chronic Rhinosinusitis Among Cement Plant Workers: a Randomized Controlled Trial.","authors":"Nguyen Quang Hung, Vo Hoang Long, Nguyen Quang Truong","doi":"10.5455/medarh.2025.79.184-189","DOIUrl":"10.5455/medarh.2025.79.184-189","url":null,"abstract":"<p><strong>Background: </strong>Chronic rhinosinusitis (CRS) is a prevalent and debilitating condition among industrial workers exposed to occupational hazards such as dust and chemical irritants. Despite its significant impact on quality of life and productivity, evidence-based interventions for occupational CRS remain limited.</p><p><strong>Objective: </strong>This study evaluates the effectiveness of combined health education and nasal irrigation in reducing CRS symptoms among direct labor workers at the Hai Phong Cement Plant, Vietnam.</p><p><strong>Methods: </strong>A randomized controlled trial was conducted from 2014 to 2015, involving 90 workers diagnosed with CRS. Participants were randomly assigned to an intervention group (n=45), receiving nasal irrigation kits and training, or a control group (n=45), receiving health education only. Health education sessions focused on improving knowledge, attitudes, and practices (KAP) related to CRS prevention. Nasal irrigation involved twice-daily rinsing with 0.9% saline solution. Outcomes were assessed using structured questionnaires, clinical examinations, and the Intervention Effectiveness Index (HQCT).</p><p><strong>Results: </strong>The health education intervention significantly improved KAP scores, with a 2967% increase in positive attitudes and an 847% improvement in understanding preventive measures. Nasal irrigation demonstrated substantial efficacy, reducing moderate nasal discharge by 58% and nasal congestion by 1600%. Objective findings revealed a 1657% increase in workers reporting no nasal cavity discharge and a 158% improvement in nasal mucosal health. After six months, 60% of the nasal irrigation group reported \"good\" improvement, compared to 11.1% in the control group (p < 0.05).</p><p><strong>Conclusions: </strong>This study highlights the synergistic potential of health education and nasal irrigation in managing occupational CRS. Nasal irrigation, in particular, emerged as a highly effective, low-cost intervention for alleviating CRS symptoms in high-risk industrial settings. These findings underscore the importance of integrating non-pharmacological approaches into occupational health programs to safeguard respiratory health among workers exposed to environmental hazards.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 3","pages":"184-189"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12253579/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144628305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Covid-19 With the Occurrence of a Depressive Disorder.","authors":"Danijel Bijedic, Elvir Becirovic, Jasminka Petrovic, Humera Porobic Jahic, Alma Trnacevic, Azra Zigic","doi":"10.5455/medarh.2025.79.211-214","DOIUrl":"10.5455/medarh.2025.79.211-214","url":null,"abstract":"<p><strong>Background: </strong>Depressive disorder is characterized by a persistent low mood (sadness, irritability, or emptiness) or a loss of pleasure, accompanied by other cognitive, behavioral, or neurovegetative symptoms that significantly impair a person's ability to function. Anxiety and fear-related disorders are marked by excessive anxiety and fear, which lead to behavioral disturbances and cause significant distress or impair personal, family, social, educational, occupational, or other key areas of functioning.</p><p><strong>Objective: </strong>The aim of this study was to analyze whether there are differences in the development of depressive symptoms between COVID-19 patients and patients with symptoms of the flu or common cold.</p><p><strong>Methods: </strong>This is a prospective study that included sixty participants: thirty with COVID-19 and thirty without COVID-19. Data were collected from the ambulatory observational records of participants, documenting their symptoms. We analyzed the relationship between variables such as age, sex, education, and the level of potential depression. The participants were divided into two groups: one consisting of individuals with COVID-19 and the other of individuals without COVID-19. All participants were male and female, aged between 40 and 65 years, and had no previous history of depressive disorder. The first group consisted of patients with COVID-19 who were treated at home but were examined at our outpatient clinic and subsequently sent home.</p><p><strong>Results: </strong>Statistical data processing was performed using the Excel program and the R statistical data processing program. Percentages are calculated in relation to 30 respondents in each group.There was no statistically significant correlation between the level of education in Group 1 and the development of depression(Spearman ro=0.007, P=0.972). In Group 1 (Covid ) there is a statistically significant correlation between the age of the subjects and the development of depression (Spearman ro=0.44, P=0.015). A positive value of the Spearman correlation coefficient means that the score increases with the age of the respondent. Three questions with the highest score in group 1 were: Question 2=71, Questions 15 and 16=66, Question 14=65; three questions with the highest score in group 2 were: Question 2=74, Question 1 =50, Question 18=46.</p><p><strong>Conclusion: </strong>COVID-19 can contribute to the development of depression. In our study, 16.7% of patients with COVID-19 showed signs of depression, with 10% experiencing mild depression and 6.7% experiencing moderate depression. Patients in the first group, particularly those of older age, were more likely to develop mild or moderate depression associated with COVID-19. Additionally, no statistically significant correlation was found between the level of education in Group 1 and the development of depression.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 3","pages":"211-214"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12253576/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144628370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}