{"title":"Leber's Hereditary Optic Neuropathy.","authors":"Allen Popovic-Beganovic, Vladislav Dzinic","doi":"10.5455/medarh.2025.79.241-248","DOIUrl":"https://doi.org/10.5455/medarh.2025.79.241-248","url":null,"abstract":"<p><strong>Background: </strong>Leber's hereditary optic neuropathy (LHON) is the most common maternally inherited disease linked to mitochondrial DNA (mtDNA). The patients present with subacute asymmetric bilateral vision loss. It is a rare disease that typically affects young adults-men more than women-and is a relatively common cause of blindness. The majority (more than 95%) of patients have one of three mtDNA point mutations: m.14484T→C, m.3460G→A, or m.11778G→ A.The hallmark of hereditary optic neuropathies determined by mitochondrial dysfunction is the vulnerability and degeneration of retinal ganglion cells (RGC). Due to its low prevalence in the population (1:50,000), this diagnosis is often overlooked, misdiagnosed, and mismanaged, which may exacerbate symptoms.</p><p><strong>Objective: </strong>The aim of the paper is to present the complexity and challenge of making the correct diagnosis in patients with progressive vision loss.</p><p><strong>Case report: </strong>A 42-year-old patient, female, complains of a bilateral decrease in visual acuity after surgery performed under general anaesthesia. The visual acuity value at the first ophthalmological examination was 0.8 bilaterally and could not be corrected. The OCT finding was within the ''reference values'', while the visual field finding showed non-specific changes. Further examinations by a neurologist and psychiatrist do not lead to a correct diagnosis. After a long time, genetic testing reveals a genetic mutation and a diagnosis of LHON is made.</p><p><strong>Conclusion: </strong>Although still uncommon, the presentation of LHON in middle-aged women is possible and should be considered as one of the differential diagnoses in a patient when painless vision loss occurs.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 3","pages":"241-248"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12253580/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144628390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fatima Sabri Al-Ali, Mohammed Al-Shujaie, John Flood
{"title":"Prevalence of Body Dysmorphia in Polycystic Ovary Syndrome (PCOS) Patients.","authors":"Fatima Sabri Al-Ali, Mohammed Al-Shujaie, John Flood","doi":"10.5455/medarh.2025.79.27-33","DOIUrl":"https://doi.org/10.5455/medarh.2025.79.27-33","url":null,"abstract":"<p><strong>Background: </strong>Polycystic ovary syndrome (PCOS), a significant hormonal disorder that primarily affects young women, has a substantial impact on both their health-related quality of life and their mental well-being.</p><p><strong>Objective: </strong>To assess the prevalence and patterns of body dysmorphia in polycystic ovary syndrome (PCOS) patients in Kingdom of Bahrain and to reach a consensus regarding the relationship between body dysmorphia and PCOS.</p><p><strong>Methods: </strong>There were 132 participants involved in the study: 66 were control cases, 66 were PCOS cases. Each was given a survey form. The scoring was based on the Głębocka's self-perception scale and modified Ferriman-Gallwey hirsutism scale were used to assess about own perception to appearance, and pressure to change body shape.</p><p><strong>Results: </strong>Most of the PCOS patients in the Kingdom of Bahrain who are above 30 years old experienced body dysmorphia along with other physical changes in appearance and psychological disorders such as social anxiety and depression. About 86% of them have hirsutism which significantly affects their self-esteem and self-confidence within themselves. However, the average hair distribution volume ranges only from 1.82 to 2.53 in the different parts of the body.</p><p><strong>Conclusion: </strong>Body dysmorphia is prevalent in patients diagnosed with PCOS. It is important to understand that these manifestations of PCOS in women significantly impact their quality of life..</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 1","pages":"27-33"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045581/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring Thoracolumbar Pott's Disease in the Immunocompetent; Institutional Experience Over a Decade and Comprehensive Literature Review.","authors":"Yasser Aljehani, Naif ALkhaldi, Lama Althunayyan, Rahaf Alghamdi, Sadeem Aljamaan, Marwan Alwazzeh, Farouk Alreshaid","doi":"10.5455/medarh.2025.79.41-46","DOIUrl":"10.5455/medarh.2025.79.41-46","url":null,"abstract":"<p><strong>Background: </strong>The presentation of Pott's has a wide variation and an insidious onset, which makes timely accurate diagnosis quite challenging.</p><p><strong>Objective: </strong>To review Pott's cases to enhance the disease management and fill the literature gap regarding the approach to Pott's disease.</p><p><strong>Methods: </strong>A descriptive observational retrospective hospital-based study conducted from 2007 to 2022 at KFHU. 346 patients who were diagnosed with TB were reviewed thoroughly. Only 13 cases were labeled as Pott's disease based on imaging or microbiology testing and hence were included in this study, and other TB pulmonary and extrapulmonary cases were excluded.</p><p><strong>Results: </strong>In our analysis of 13 cases of Pott's disease, we observed a significant male predominance (69.23%) and diverse symptoms, with back pain (69.2%) being most prevalent among our patients. Lumbar involvement was the most frequently observed site (38.4%), and diagnoses were made through microbiology (69.2%) or clinical/radiological means (30.8%). Acid-fast bacilli (AFB) culture testing exhibited a positivity rate of 61.5%, while TB-PCR showed positive results in 57.1%. Imaging studies revealed vertebral lesions (90.9% CT, 81.8% MRI), abscesses (54.5% CT, 81.8% MRI), and spondylodiscitis (18.2% CT, 54.5% MRI). Treatment, administered in 92.3% of cases, involved the use of Isoniazid, Rifampicin, and Ethambutol. Surgical interventions, though less frequent, encompassed various procedures. Outcomes demonstrated a notable high cure rate of 84.9%, with a 15.4% incidence of cases experiencing loss of follow-up.</p><p><strong>Conclusion: </strong>The high cure rate of 84.9% accentuates the effectiveness of early diagnosis and comprehensive treatment strategies that combine medical and surgical interventions when necessary.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 1","pages":"41-46"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045595/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Faisal Alkhadra, Sarah Bohaligah, Zahraa Alhashim, Farah AlZahrani, Maryam Alkhalifa, Fatimah Alsaihati, Hussam Khader, Nisreen Maghraby, Mohammed Al-Hariri
{"title":"Door-to-Balloon Time and Clinical Outcome of Patients Presenting with ST-Segment Elevation Myocardial Infarction During on and off Hours: a Single Center Study.","authors":"Faisal Alkhadra, Sarah Bohaligah, Zahraa Alhashim, Farah AlZahrani, Maryam Alkhalifa, Fatimah Alsaihati, Hussam Khader, Nisreen Maghraby, Mohammed Al-Hariri","doi":"10.5455/medarh.2025.79.172-180","DOIUrl":"https://doi.org/10.5455/medarh.2025.79.172-180","url":null,"abstract":"<p><strong>Background: </strong>Timely reperfusion is crucial in patients with ST-segment elevation myocardial infarction (STEMI), with door-to-balloon time often considered a key metric for assessing quality of care. However, the impact of door-to-balloon time on clinical outcomes during off-hours remains uncertain.</p><p><strong>Objective: </strong>To compare clinical outcome and door-to-balloon time of patients with STEMI in off-hours versus on-hours in King Fahad Uni-versity Hospital (KFHU).</p><p><strong>Methods: </strong>A mixed-method, qualitative and quantitative retrospective cohort study was conducted at KFUH in Al Khobar, Saudi Arabia, including adults diagnosed with STEMI and managed with primary percutaneous coronary intervention (PCI) between May 2023 to February 2024. The sample was divided into two groups based on-duty hours. The first group comprised patients presenting during duty hours, including weekdays (Sunday to Thursday, 8 a.m. - 4 p.m.), while the second group included patients presenting during off-duty hours, which consisted of weekdays (Sunday to Thursday, 4:01 pm to 7:59 am), weekends (Friday to Saturday), national holidays, and Eid holidays.</p><p><strong>Results: </strong>The study included 79 patients (57 off-hours and 22 in-hours) diagnosed with STEMI who underwent primary PCI. The mean age of the participants was 55.0 years (±10.8), 89.9% were males, 36.7% were Saudi, and 41.8% were smokers. Off-hours presentation did not significantly impact mortality rates or complications compared to on-hours presentation (p > 0.05), Similarly, no significant association was found between door-to-balloon time and 48-hour or 30-day mortality rates (p > 0.05). The mean time was statistically significant across the on- and off-duty time groups (65.2±18.0 vs 107.4±44.5, p<0.0001). Hypotension was the only complication signifi-cantly associated with mortality at 30 days (p < 0.001).</p><p><strong>Conclusion: </strong>Our results revealed that neither door-to-balloon time nor off-hours presentation significantly affected mortality rates or complications in pa-tients with STEMI undergoing Primary PCI, with the exception of hypotension being significantly associat-ed with 30-day mortality. Further research is warranted to explore other factors that may influence STEMI outcomes beyond door-to-balloon time and presentation hours. Additionally, investigating the specific rela-tionship between hypotension and 30-day mortality could lead to improved risk stratification and manage-ment strategies for STEMI patients.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 3","pages":"172-180"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12253598/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144628371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alma Cickusic, Suzana Pavljasevic, Vahid Jusufovic, Sanja Sefic-Kasumovic, Adisa Pilavdzic Hasic, Meliha Halilbasic
{"title":"C-reactive Protein Levels in Prediction of the Development or the Progression of Agerelated Macular Degeneration in Patients Examined at Tuzla Canton.","authors":"Alma Cickusic, Suzana Pavljasevic, Vahid Jusufovic, Sanja Sefic-Kasumovic, Adisa Pilavdzic Hasic, Meliha Halilbasic","doi":"10.5455/medarh.2025.79.47-51","DOIUrl":"https://doi.org/10.5455/medarh.2025.79.47-51","url":null,"abstract":"<p><strong>Background: </strong>Age-related macular degeneration (ARMD) is a chronic, incurable, progressive, multifactorial, neurodegenerative disease, which is one of the leading causes of visual impairment, among individuals above 60 years of age in developed countries. Over the past decades, the role of inflammation and CRP in the pathogenesis of ARMD has been investigated.</p><p><strong>Objective: </strong>The study aimed to investigate the association between inflammation or CRP levels in prediction the development or the progression of ARMD.</p><p><strong>Methods: </strong>This retrospective-prospective, case-control study, was conducted at the Clinic for Eye Diseases, University Clinical Center Tuzla, from 2020. to 2024. Two group of participants were included in this study. The first group (n=100 patients) consisted of patients diagnosed with different stages of ARMD, and second, control group (n=100 patients) consisted of patients without ARMD. The study included subjects of both sexes, divided into three age categories (≤55; 56-66; ≥67 years). Detailed ocular and systemic evaluations were performed, including fundus examination and OCT angiography. A 5mL sample of venous blood was colected to determine serum CRP levels, for the both group of patients, using latex immunoassay method. Statistical analysis, including Student's t-test, Chi square test and posthoc (Turkey) tests, was conducted using SPSS 26 for Windows, with p<0,05 considered significant.</p><p><strong>Results: </strong>Out of 100 patients, 34 were having early, 18 intermediate and 48 were having advanced stages of ARMD. The mean serum CRP levels in the ARMD group (8.39±27.22mg/L) were significantly higher compared to the control group, (2.52±5.35mg/L), p=0,000. Also, serum CRP values by age category, between ARMD subjects and the control group, showed statistically significant differences in all age groups: ≤55 p=0.032; 56-66 p=0.019; ≥67 p=0.000. The mean serum CRP levels was 6.6±6.9 mg/L, 10±13.3 mg/L and 16±22.7 mg/L, in early, intermediate and advanced ARMD, respectively. Comparing these CRP values and different stages of ARMD, there were found statistically significant differences between the three stages. Furthermore, these results showed that mean CRP values increase with disease severity.</p><p><strong>Conclusion: </strong>Based on the obtained results serum CRP levels are significant risk factor in predicting the development and the progression of ARMD. Also, these results emphasize the role of systemic inflammation in the development and progression of ARMD.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 1","pages":"47-51"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144015480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sympathetic Ophthalmia After Complicated Cataract Surgery.","authors":"Nguyen Thanh Nam, Nguyen Quynh Anh","doi":"10.5455/medarh.2025.79.64-66","DOIUrl":"10.5455/medarh.2025.79.64-66","url":null,"abstract":"<p><strong>Background: </strong>Sympathetic ophthalmia (SO) is a bilateral, diffuse granulomatous panuveitis that can occur after a penetrating trauma or intraocular surgery. The time from ocular injury to the onset of sympathetic ophthalmia varies greatly, ranging from several days to decades.</p><p><strong>Objective: </strong>We report on the diagnostic dilemma and clinical outcome of patient with sympathetic ophthalmia within 2 weeks of cataract surgery.</p><p><strong>Case presentation: </strong>A patient underwent left eye cataract surgery that was complicated by postoperative iris prolapse through the corneal wound. The wound was sutures with iris still entrapped, and he presented to our clinic 1 week later with bilateral vision loss and panuveitis. After workup for other inflammatory or infectious causes, sympathetic ophthalmia was diagnosed, and the patient was treated with topical and systemic corticosteroids. One month later, visual acuity improved markedly in both eyes, and inflammatory symptoms and findings resolved. Sympathetic ophthalmia may occur soon after cataract surgery and can be confused with infectious endophthalmitis, which must be considered.</p><p><strong>Conclusion: </strong>Prompt diagnosis and institution of corticosteroid therapy is essential and may result in significant visual improvement in both eyes.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 1","pages":"64-66"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045593/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hung Quang Nguyen, Hoa Hong Thi Doan, Long Hoang Vo
{"title":"Diagnostic Challenges of Tuberculous Meningitis Initially Presenting as Otomastoiditis.","authors":"Hung Quang Nguyen, Hoa Hong Thi Doan, Long Hoang Vo","doi":"10.5455/medarh.2025.79.71-77","DOIUrl":"10.5455/medarh.2025.79.71-77","url":null,"abstract":"<p><strong>Background: </strong>Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), remains a major global health problem, with one-third of the world's population infected.</p><p><strong>Objective: </strong>This report presents five cases of tuberculous meningitis with a particular emphasis on the symptoms and signs of otitis media that, in various combinations, should raise suspicion for tuberculous meningitis.</p><p><strong>Case presentation: </strong>These cases underscore the diagnostic challenges and clinical complexities associated with tuberculous otitis media, particularly when there is concurrent involvement of the central nervous system. It is crucial for physicians to maintain a high index of suspicion for tuberculosis in patients exhibiting chronic otorrhea that does not respond to conventional treatments, especially in endemic regions or in the presence of systemic symptoms. The use of advanced diagnostic tools and a multidisciplinary approach is essential for achieving timely diagnosis and effective management. Early initiation of antituberculous therapy, coupled with surgical interventions when warranted, can lead to favorable clinical outcomes. However, it is important to note that some patients may experience long-term sequelae, which highlights the necessity for prompt diagnosis and treatment to improve prognosis in those presenting with otitis media.</p><p><strong>Conclusion: </strong>The findings of this case series contribute to a better understanding of the relationship between otitis media and tuberculous meningitis, advocating for increased awareness among healthcare providers to facilitate early recognition and intervention.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 1","pages":"71-77"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Janja Konjevod, Vanja Djukic, Tomislav Vukic, Klara Brekalo, Sara Abbaci Jangjel, Stefan Dimov, Rajko Fures, Vilmica Kapac, Mario Fuckar
{"title":"A Rare Case of Idiopathic Omental Necrosis in a Young Adult: Diagnostic Challenges and Management.","authors":"Janja Konjevod, Vanja Djukic, Tomislav Vukic, Klara Brekalo, Sara Abbaci Jangjel, Stefan Dimov, Rajko Fures, Vilmica Kapac, Mario Fuckar","doi":"10.5455/medarh.2025.79.237-240","DOIUrl":"https://doi.org/10.5455/medarh.2025.79.237-240","url":null,"abstract":"<p><strong>Background: </strong>Idiopathic omental infarction (IOI) is a rare cause of acute abdominal pain that can clinically mimic more common conditions, such as acute appendicitis. IOI occurs due to vascular compromise of the greater omentum, leading to ischemia, pain, and often necrosis. Preoperative diagnosis remains challenging due to nonspecific clinical and laboratory findings, as well as the fact that clinicians rarely include IOI as a \"usual suspect\" in the differential diagnosis. Therefore, the condition is commonly identified intraoperatively.</p><p><strong>Objective: </strong>The aim of this article was to present a rare case of idipathic omental necrosis in young adult with description of appropriate diagnostic challanges and management.</p><p><strong>Methods: </strong>We present the case of a 23-year-old previously healthy male who was admitted for suspected acute appendicitis based on right lower quadrant pain, nausea, vomiting, and elevated inflammatory markers. Exploratory laparoscopy revealed no signs of appendicitis but identified hemoperitoneum and a necrotic segment of the greater omentum in its right upper segment. Appendectomy and resection of the infarcted omental tissue were performed. Histopathological analysis confirmed the diagnosis of omental infarction as well as the absence of histopathological signs of acute appendicitis.</p><p><strong>Conclusion: </strong>Idiopathic omental infarction, though rare, should be considered in the differential diagnosis of acute abdomen, particularly when clinical findings do not align with typical appendicitis. Advanced imaging modalities such as contrast-enhanced CT can facilitate preoperative diagnosis, potentially preventing unnecessary surgical interventions. However, in cases of diagnostic uncertainty, surgical exploration remains a mainstream approach. Awareness of this condition can improve diagnostic accuracy and optimize patient management.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 3","pages":"237-240"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12253603/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144628369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Minimally Invasive Aortic Root Surgery (Mini-Bentall): Case Series Study.","authors":"Harun Avdagic, Mustafa Tabakovic, Miha Antonic, Alisa Krdzalic, Selma Sijercic, Melika Piric, Maida Sahinovic","doi":"10.5455/medarh.2025.79.233-236","DOIUrl":"https://doi.org/10.5455/medarh.2025.79.233-236","url":null,"abstract":"<p><strong>Background: </strong>The upper mini sternotomy Bentall (mini-Bentall) procedure may result in less trauma and earlier recovery compared with the usual full sternotomy Bentall procedure (Usual Bentall-DeBono procedure).</p><p><strong>Objective: </strong>This study evaluates the efficacy and safety of mini sternotomy aortic root surgery (MSARS), a minimally invasive technique designed to reduce surgical trauma, improve postoperative recovery, and lower healthcare costs.</p><p><strong>Methods: </strong>The upper mini sternotomy (UMS) approach was performed in ten patients focusing on standardized surgical procedures, and rigorous postoperative care. Key findings indicate that MSARS markedly reduces postoperative complications, ICU stay, and overall hospital stay compared to traditional sternotomy.</p><p><strong>Results: </strong>The median postoperative length of stay was seven days for MSARS versus 11 days for traditional sternotomy, with ICU stays of 27 hours and 105 hours, respectively. Our study also highlights the cost-effectiveness of MSARS, with decreased hospital costs per patient due to reduced ICU resource utilization and shorter hospital stays. These findings suggest that MSARS is a valuable and advantageous alternative to traditional sternotomy, offering substantial benefits in terms of patient outcomes and healthcare efficiency.</p><p><strong>Conclusion: </strong>Mini sternotomy aortic root surgery via partial upper sternotomy could be a safe alternative to the full median sternotomy, marking a significant advancement in the field of cardiac surgery.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 3","pages":"233-236"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12253582/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144628391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Effects of Date Consumption on Labor and Vaginal Birth.","authors":"Mohammad Abou El-Ardat, Zarema Obradovic, Dzenana Saldo, Minela Velagic, Aida Omeragic, Nedim Galijasevic","doi":"10.5455/medarh.2025.79.56-60","DOIUrl":"https://doi.org/10.5455/medarh.2025.79.56-60","url":null,"abstract":"<p><strong>Background: </strong>Date palm fruits (Phoenix dactylifera L.) are a widely available product that contains numerous macronutrients including a high sugar content. Research has shown that date fruit extracts possess antibacterial and antifungal properties, as well as antimutagenic and antiatherogenic effects. Date fruit can also have a beneficial effect on the female reproductive system. Several studies have examined the impact of date consumption during pregnancy on the outcome of labor, providing useful results.</p><p><strong>Objective: </strong>This study aims to determine the effects of date fruit consumption on the onset and progression of labor.</p><p><strong>Methods: </strong>The study included 120 pregnant women who were pregnant at GAK Sarajevo, in the period from 01.01. 2020 to 31.12. 2020. The patients were divided into two groups, the first group of 60 patients who consumed 6 dates during the last four weeks of pregnancy, and the second group of 60 patients who did not consume dates during pregnancy.</p><p><strong>Results: </strong>There was a significant positive effect of consuming date fruits on maternal outcomes in the first and third stages of labor. The group of pregnant women who consumed dates had a shortened latent phase of labor, which meant that their cervix reached maximum dilation (10 cm) faster. Pregnant women in this group gave birth 8.5 hours faster than pregnant women who did not consume dates, in whom labor lasted about 15 hours. Of the 60 pregnant women in the first group, 60% had a spontaneous natural birth, and only 40% of the patients received oxytocin, because dates enhance the effect of oxytocin, which is responsible for uterine contractions.</p><p><strong>Conclusion: </strong>This study showed a promising effect of consuming date fruits on the duration of the stages of labor. Saturated and unsaturated fatty acids found in dates stimulate the production of prostaglandins, which are necessary for labor. Dates are also rich in folic acid, vitamin K, iron, potassium, and magnesium.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"79 1","pages":"56-60"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}