Medical archives (Sarajevo, Bosnia and Herzegovina)最新文献

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Thirty Years of Editorial Experience of the Oldest Bosnia and Herzegovina Medical Journal "Medicinski Arhiv/Medical Archives". 波斯尼亚和黑塞哥维那最古老的医学杂志《梅迪斯基艾滋病病毒/医学档案》三十年的编辑经验。
Medical archives (Sarajevo, Bosnia and Herzegovina) Pub Date : 2024-01-01 DOI: 10.5455/medarh.2024.78.266-273
Izet Masic
{"title":"Thirty Years of Editorial Experience of the Oldest Bosnia and Herzegovina Medical Journal \"Medicinski Arhiv/Medical Archives\".","authors":"Izet Masic","doi":"10.5455/medarh.2024.78.266-273","DOIUrl":"10.5455/medarh.2024.78.266-273","url":null,"abstract":"","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 4","pages":"266-273"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11838827/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143470334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The use of Tranexamic Acid in Case of Patient with Intracerebral Hemorrhage After a Coronary Procedure-Case Report. 氨甲环酸在冠状动脉手术后脑出血患者中的应用-病例报告。
Medical archives (Sarajevo, Bosnia and Herzegovina) Pub Date : 2024-01-01 DOI: 10.5455/medarh.2024.78.317-321
Amra Salkic, Amel Amidzic, Stoja Eric, Nermina Gorana-Polimac, Naida Tiro, Merita Tiric-Campara
{"title":"The use of Tranexamic Acid in Case of Patient with Intracerebral Hemorrhage After a Coronary Procedure-Case Report.","authors":"Amra Salkic, Amel Amidzic, Stoja Eric, Nermina Gorana-Polimac, Naida Tiro, Merita Tiric-Campara","doi":"10.5455/medarh.2024.78.317-321","DOIUrl":"10.5455/medarh.2024.78.317-321","url":null,"abstract":"<p><strong>Background: </strong>Tranexamic acid can prevent death from bleeding after trauma and postpartum hemorrhage.</p><p><strong>Objective: </strong>The aim of the paper was to assess whether tranexamic acid reduces hematoma expansion and improves outcome in adults with stroke caused by intracerebral hemorrhage.</p><p><strong>Case presentation: </strong>Administration of Tranexamic acid in a patient after a diagnosis of intracerebral hematoma, which occurred after coronary stent implantation. Intracerebral hematoma, or neurological deficit, occurs one day after cardiac surgery in the patient. The case report will present the radiological resolution of the intracerebral hematoma, as well as the improvement of the clinical picture, neurological deficit, in the patient during a one-month follow-up, after the administration of Tranexamic acid.</p><p><strong>Conclusion: </strong>Tranexemic acid is affordable, easy to administer, appears to be safe, and is widely available, so even a modest treatment effect can have an important global impact, and it is necessary to consider its more frequent use, as well as to initiate larger randomized trials.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 4","pages":"317-321"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11838825/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143470332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Less Invasive Surfactant Administration (LISA) Versus INSURE Method in Preterm Infants: a Retrospective Study. 早产儿微创表面活性物质管理 (LISA) 与 INSURE 方法的对比:一项回顾性研究。
Medical archives (Sarajevo, Bosnia and Herzegovina) Pub Date : 2024-01-01 DOI: 10.5455/medarh.2024.78.112-116
Gianluca Dini, Maria Grazia Santini, Federica Celi
{"title":"Less Invasive Surfactant Administration (LISA) Versus INSURE Method in Preterm Infants: a Retrospective Study.","authors":"Gianluca Dini, Maria Grazia Santini, Federica Celi","doi":"10.5455/medarh.2024.78.112-116","DOIUrl":"https://doi.org/10.5455/medarh.2024.78.112-116","url":null,"abstract":"<p><strong>Background: </strong>Respiratory distress syndrome (RDS) is a major cause of morbidity and mortality in preterm infants. Early nasal CPAP and selective administration of surfactant via the endotracheal tube are widely used in the treatment of RDS in preterm infants.</p><p><strong>Objective: </strong>The aim of this study was to compare the need for intubation and mechanical ventilation after surfactant delivery between LISA-treated and INSURE-treated premature infants with respiratory distress syndrome (RDS).</p><p><strong>Methods: </strong>Retrospective registry-based cohort study enrolled 36 newborns admitted to the neonatal intensive care unit of the \"Santa Maria\" Hospital of Terni between 2016 and 2023. As a primary outcome, we followed the need for intubation and mechanical ventilation within 72 hours of life, while the secondary outcomes were major neonatal morbidities and death before discharge.</p><p><strong>Results: </strong>The LISA group and the INSURE group included 13 and 23 newborns respectively. Demographic features showed no significant differences between the two groups. The need for mechanical ventilation in the first 72 hours of life was similar in both groups (p >0.99). There were no significant differences in morbidities.</p><p><strong>Conclusion: </strong>LISA and INSURE are equally effective modalities for surfactant administration for the treatment of RDS in preterm infants.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 2","pages":"112-116"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10983101/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characteristics of Patients With Acute Coronary Syndrome and Normal Electrocardiogram. 心电图正常的急性冠状动脉综合征患者的特征。
Medical archives (Sarajevo, Bosnia and Herzegovina) Pub Date : 2024-01-01 DOI: 10.5455/medarh.2024.78.100-104
Aleksandra Ljubojevic, Sofija Aleksandra Neskovic, Ivona Vranic, Ivan Stankovic
{"title":"Characteristics of Patients With Acute Coronary Syndrome and Normal Electrocardiogram.","authors":"Aleksandra Ljubojevic, Sofija Aleksandra Neskovic, Ivona Vranic, Ivan Stankovic","doi":"10.5455/medarh.2024.78.100-104","DOIUrl":"https://doi.org/10.5455/medarh.2024.78.100-104","url":null,"abstract":"<p><strong>Background: </strong>Patients with acute coronary syndrome (ACS) and normal electrocardiogram (ECG) may have an increased risk of late diagnosis and complications of the disease.</p><p><strong>Objective: </strong>To study the demographic, angiographic and echocardiographic characteristics of patients hospitalized for ACS in whom the ECG was normal on admission to the hospital.</p><p><strong>Methods: </strong>This retrospective study included patients who were hospitalized for ACS without ST-elevation between 2015 and 2023 and who had coronary artery disease (CAD) confirmed by coronary angiography. By further inspection of the electronic databases, patients with ACS who had a normal ECG on admission were filtered out and analyzed separately.</p><p><strong>Results: </strong>Of the total 3137 patients with suspected ACS without ST-elevation, 129 patients (4.1%) were diagnosed as having ACS with a normal ECG. In three patients a non-atherosclerotic cause for the ACS was found. A significantly higher proportion of patients had single-vessel (54.3%) compared to two-vessel (29.5%) and three-vessel (14%) CAD. In addition to a normal ECG, 5.7% of patients with single-vessel CAD and 3.5% of patients with multi-vessel CAD had normal troponin levels and normal regional LV systolic function on echocardiography.</p><p><strong>Conclusion: </strong>Less than 5% of hospitalized patients with ACS without ST-elevation had a normal ECG on admission. The majority of these patients have single-vessel CAD. In about 5% of patients with single-vessel CAD, neither elevated troponin levels nor LV asynergy are detected.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 2","pages":"100-104"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10983090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140862194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Relationship Between KI67 Expression and Grading with Chemotherapy Response in Triple-Negative Breast Cancer Patients at Haji Adam Malik General Hospital, Medan. 棉兰市哈吉-亚当-马利克综合医院三阴性乳腺癌患者 KI67 表达和分级与化疗反应的关系
Medical archives (Sarajevo, Bosnia and Herzegovina) Pub Date : 2024-01-01 DOI: 10.5455/medarh.2024.78.285-289
Edy Anugrah Putra, Dedy Hermansyah, Endi Taris Pasaribu, Putri Chairani Eyanoer
{"title":"The Relationship Between KI67 Expression and Grading with Chemotherapy Response in Triple-Negative Breast Cancer Patients at Haji Adam Malik General Hospital, Medan.","authors":"Edy Anugrah Putra, Dedy Hermansyah, Endi Taris Pasaribu, Putri Chairani Eyanoer","doi":"10.5455/medarh.2024.78.285-289","DOIUrl":"10.5455/medarh.2024.78.285-289","url":null,"abstract":"<p><strong>Background: </strong>The response to chemotherapy in TNBC varies greatly, highlighting the need for predictive factors to estimate the success of the therapy.</p><p><strong>Objective: </strong>The primary aim of this study is to analyze the relationship between Ki67 expression and clinicopathological features with chemotherapy response in locally advanced TNBC.</p><p><strong>Methods: </strong>This retrospective study utilized secondary data from the medical records of locally advanced TNBC patients at Haji Adam Malik General Hospital, Medan. Out of an initial sample of 50 patients, 35 met the inclusion criteria, which required a confirmed TNBC diagnosis through histopathological and immunohistochemical examination, as well as complete clinical data. Chemotherapy response was assessed based on the World Health Organization (WHO) criteria, ensuring a standardized evaluation of treatment outcomes.</p><p><strong>Results: </strong>The majority of patients were aged ≥50 years (54.5%), with a dominant tumor size of 2-5 cm (69.7%) and high histological grading (Grade 3: 60.6%). A total of 45.5% of patients exhibited high Ki67 expression (≥30%). Chemotherapy response was categorized as complete response (12.1%), partial response (45.5%), stable disease (30.3%), and progressive disease (12.1%). Statistical analysis revealed a significant relationship between Ki67 expression and chemotherapy response (p=0.02), with patients exhibiting high Ki67 expression more frequently achieving complete or partial response.</p><p><strong>Conclusion: </strong>High Ki67 expression is a critical indicator for predicting chemotherapy response in TNBC. Integrating Ki67 assessment with other clinicopathological factors is highly recommended to enhance predictive accuracy and optimize therapeutic planning for more effective treatment outcomes.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 4","pages":"285-289"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11838830/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143470330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Esophageal Injury After Anterior Cervical Spine Fixation: What Can Thoracic Surgeons Offer? 颈椎前路固定后食管损伤:胸外科医生能提供什么?
Medical archives (Sarajevo, Bosnia and Herzegovina) Pub Date : 2024-01-01 DOI: 10.5455/medarh.2024.78.290-295
Humood A Alsadery, Yesser Aljehani, Farouk Alreshaid, Yasser Elghoneimy, Omar A Bamalan, Abdulrahman Alblowi, Jumana Alhelal, Ayman Elbaz, Moustafa Aboollo
{"title":"Esophageal Injury After Anterior Cervical Spine Fixation: What Can Thoracic Surgeons Offer?","authors":"Humood A Alsadery, Yesser Aljehani, Farouk Alreshaid, Yasser Elghoneimy, Omar A Bamalan, Abdulrahman Alblowi, Jumana Alhelal, Ayman Elbaz, Moustafa Aboollo","doi":"10.5455/medarh.2024.78.290-295","DOIUrl":"10.5455/medarh.2024.78.290-295","url":null,"abstract":"<p><strong>Background: </strong>The anterior approach for cervical spine surgery was introduced in the late 1950's and was then extensively used with a known considered risk for an esophageal injury.</p><p><strong>Objective: </strong>Therefore, we designed this study to look into our institution's experience in the treatment of esophageal injury post cervical spine fixation looking at possible causes, presentation and risk factors.</p><p><strong>Methods: </strong>A retrospective analysis of esophageal perforation cases secondary to cervical spine fixation, encountered in King Fahad hospital of the University (Eastern province, Dammam, Saudi Arabia) in between (2008-2019) were studied.</p><p><strong>Results: </strong>The patients included were 11, in which the most common presenting symptoms were dysphagia, neck pain, persistent discharge from the cervical wound with or without food particles and odynophagia, while the mean period for presentation was 358.9 days (ranging from 4 to 2555 days). The pharyngo-esophageal perforation repair was done in 9 patients, while 2 patients were treated conservatively. In addition, supportive measures (i.e., frequent wound care, broad spectrum intravenous antibiotics, non per oral and adequate feeding via alternative routes) were done for all patients.</p><p><strong>Conclusion: </strong>Esophageal injury, although uncommon in anterior spinal approach, still considered a life-threatening complication and need a low threshold of suspicion.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 4","pages":"290-295"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11838835/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143470340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Miliary Tuberculosis in a Two-Year-Old Child: A Case Report from a Low-Prevalence Region. 1例2岁儿童军旅结核病:来自低流行地区的病例报告。
Medical archives (Sarajevo, Bosnia and Herzegovina) Pub Date : 2024-01-01 DOI: 10.5455/medarh.2024.78.247-249
Gianluca Dini, Sara Ceccarelli, Barbara Vecchi, Federica Celi
{"title":"Miliary Tuberculosis in a Two-Year-Old Child: A Case Report from a Low-Prevalence Region.","authors":"Gianluca Dini, Sara Ceccarelli, Barbara Vecchi, Federica Celi","doi":"10.5455/medarh.2024.78.247-249","DOIUrl":"10.5455/medarh.2024.78.247-249","url":null,"abstract":"<p><strong>Background: </strong>Tuberculosis (TB) remains the leading cause of death caused by a single infectious agent.</p><p><strong>Objective: </strong>We report a case of miliary TB in a 2-year-old child who presented with a history of constipation, weight loss, marked abdominal distension with hepatosplenomegaly.</p><p><strong>Case presentation: </strong>In children, TB often presents with a wide range of non-specific clinical and radiological manifestations, making diagnosis challenging, particularly in regions with low prevalence. We report the case of a two-year-old female with a history of constipation, weight loss, marked abdominal distension with hepatosplenomegaly, who was later diagnosed with miliary tuberculosis.</p><p><strong>Conclusion: </strong>This case highlights an unusual presentation of miliary TB in a very young child, a demographic in which it is infrequently observed. Miliary TB remains a severe and potentially fatal condition, particularly when diagnosis and treatment are delayed. The diagnosis is usually made based on the clinical presentation, supported by a classic miliary pattern on chest X-ray.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 3","pages":"247-249"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11813211/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143412101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Cutoff Point Prostate Specific Antigen (PSA) and Prostate Specific Antigen Density (PSAD) in Patients with Suspected Prostate Cancer. 评估疑似前列腺癌患者的前列腺特异性抗原 (PSA) 和前列腺特异性抗原密度 (PSAD) 临界点。
Medical archives (Sarajevo, Bosnia and Herzegovina) Pub Date : 2024-01-01 DOI: 10.5455/medarh.2024.78.12-15
Besut Daryanto, Rizal Trianto, Kurnia Penta Seputra, Athaya Febriantyo Purnomo
{"title":"Evaluation of Cutoff Point Prostate Specific Antigen (PSA) and Prostate Specific Antigen Density (PSAD) in Patients with Suspected Prostate Cancer.","authors":"Besut Daryanto, Rizal Trianto, Kurnia Penta Seputra, Athaya Febriantyo Purnomo","doi":"10.5455/medarh.2024.78.12-15","DOIUrl":"10.5455/medarh.2024.78.12-15","url":null,"abstract":"<p><strong>Background: </strong>Prostate cancer is the second leading cause of cancer death in men worldwide. There is no national standard for PSA cut-off levels even through the transrectal prostate biopsy procedure causes many serious complications such as bleeding, infection, and sepsis. Therefore, determining cut-off levels for PSA and PSAD is essential to avoid unnecessary biopsies.</p><p><strong>Objective: </strong>This study aims to determine the Prostate Specific Antigen (PSA) and Prostate Specific Antigen Density (PSAD) cut-off points in patients with suspected prostate cancer.</p><p><strong>Methods: </strong>A retrospective study was conducted from January 2018 until March 2021 in Saiful Anwar General Hospital Malang Indonesia. Inclusion criterias were patients with suspected prostate cancer; > 50 years old; underwent PSA, PSAD, and prostate biopsy. Exclusion criterias were patients refuse to participate in the study and incomplete patient medical record data. Medical records from 53 patients who underwent transrectal ultrasonography (TRUS)-guided prostate biopsy were reviewed. Statistical analysis was performed using Mann-Whitney U, Chi-Square, Fisher's Exact, and Receiver Operator Characteristic (ROC) curves.</p><p><strong>Results and discussion: </strong>Medical records conducted 53 patients who met inclusion criteria and underwent transrectal ultrasonography (TRUS)-guided prostate biopsy were reviewed. PSA cut off level for prostate biopsy was 19.71 ng/ml with a sensitivity of 69.23% and a specificity of 72.5%. The positive predictive value is 45% and the negative predictive value is 87.87%. PSAD cut off level for prostate biopsy was 0.4113 with a sensitivity of 61.54% and a specificity of 63.16%. The positive predictive value is 36.36% and the negative predictive value is 82.76%.</p><p><strong>Conclusion: </strong>Results from this study, the cut off levels of PSA and PSAD in prostate disease patients is higher than the recommended cut off; prostate cancer is the largest malignancy in men worldwide and has a higher incidence in the older age and high serum PSA levels group.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 1","pages":"12-15"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10928674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140121699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Factors Influenced on the Effectiveness of Percutaneous Nephrolithotomy. 评估影响经皮肾镜取石术效果的因素。
Medical archives (Sarajevo, Bosnia and Herzegovina) Pub Date : 2024-01-01 DOI: 10.5455/medarh.2024.78.33-38
Tran Quoc Hoa, Than Thi Minh Nguyet, Nguyen Thanh Van Anh, Le Tuan Linh, Nguyen Minh Duc, Hoang Dinh Au
{"title":"Evaluation of Factors Influenced on the Effectiveness of Percutaneous Nephrolithotomy.","authors":"Tran Quoc Hoa, Than Thi Minh Nguyet, Nguyen Thanh Van Anh, Le Tuan Linh, Nguyen Minh Duc, Hoang Dinh Au","doi":"10.5455/medarh.2024.78.33-38","DOIUrl":"10.5455/medarh.2024.78.33-38","url":null,"abstract":"<p><strong>Background: </strong>Generally, there are many methods for the treatment of urinary stones, of which percutaneous nephrolithotomy (PCNL) is a minimally invasive and highly effective method, and now become the first-line management for urinary stones, especially in the cases of complex stones and staghorne calculi. Accurate assessment of stone location, stone morphology, degree of hydronephrosis as well as urinary system abnormalities is extremely important in the percutaneous nephrolithotomy strategy.</p><p><strong>Objective: </strong>The aim of this study was to evaluate the S.T.O.N.E score as well as other factors that influenced the effectiveness of PCNL.</p><p><strong>Methods: </strong>Descriptive study on 71 patients with kidney stones, who underwent multi-slice CT scan of the urinary system before PCNL and then PCNL at Hanoi Medical University Hospital from July 2022 to July 2023. All patients received the informed consent and agreed to participate in the study. The factors included the stone area, the track length (from the skin surface to the stone central), the degree of urinary tract dilatation, the number of involved calyces, the density of stone, the renal parenchyma thickness, the ureteral wall thickness and fat infiltration measured on MSCT non-contrast phase. These factors were used to predict the effectiveness of PCNL including the stone clearance rate (SCR) and the operation time.</p><p><strong>Results: </strong>The mean age of the patient group was 53.8±12.3. The male/female ratio was 1.54. There was a significant difference (p<0.05) between the following factors and the operation time: the stone area (<400, 400-799, 800-1599 and >1600 mm2), the degree of urinary tract dilatation (no or might and moderate or severe dilatation), the number of involved calyces (≤ 2, 3 and staghorne calculi), the renal parenchyma thickness (<18 mm and ≥18mm). In contrast, there were no significant differences between the following factors and the surgery time (p>0.05): the track length (<100 and ≥100 mm), and the stone density (<950 and ≥950 HU). Regarding the S.T.O.N.E score (included five factors: Size, Track length, Obstruction, Number of involved calyces, and Evaluation of stone density), there was a strong correlation between S.T.O.N.E score and the surgery time (p<0.001, r=0.94), and the SCR (p=0.001, r=-0.97).</p><p><strong>Conclusion: </strong>The evaluation of these factors played an important role in the prediction of the effectiveness of PCNL.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 1","pages":"33-38"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10928681/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140121700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Different Surgical Approaches on Morbidity and Mortality in Patients with Borderline Resectable Pancreatic Head Carcinoma. 不同手术方法对边缘可切除胰头癌患者发病率和死亡率的影响
Medical archives (Sarajevo, Bosnia and Herzegovina) Pub Date : 2024-01-01 DOI: 10.5455/medarh.2024.78.29-32
Edin Hodzic, Sadat Pusina, Mirhan Salibasic, Ajdin Rovcanin, Emsad Halilovic, Naida Herenda
{"title":"Impact of Different Surgical Approaches on Morbidity and Mortality in Patients with Borderline Resectable Pancreatic Head Carcinoma.","authors":"Edin Hodzic, Sadat Pusina, Mirhan Salibasic, Ajdin Rovcanin, Emsad Halilovic, Naida Herenda","doi":"10.5455/medarh.2024.78.29-32","DOIUrl":"10.5455/medarh.2024.78.29-32","url":null,"abstract":"<p><strong>Background: </strong>Radical surgical resection for pancreatic head carcinoma offers a chance for cure but unfortunately is only available to a limited number of patients. For a significant number of patients, palliative surgery remains the only option. The question of the most effective approach for patients with borderline resectable pancreatic head carcinoma (BRPHC) remains unresolved. Objective: The aim of the study was to compare the morbidity and mortality following R1 duodenocephalic pancreatectomy and double palliative bypass to explore the most optimal surgical treatment for patients with BRPHC.</p><p><strong>Methods: </strong>Our retrospective cohort study included 64 patients with BRPHC who underwent surgery from 2012 to 2019, with postoperative follow-up for three years. Morbidity and mortality parameters were examined based on the type of surgical treatment: R1 duodenocephalic pancreatectomy or palliative double bypass. Chi-square test, univariate regression, and Kaplan-Meier analysis were used as basic statistical methods in the analysis of the results.</p><p><strong>Results: </strong>Patients undergoing R1 duodenocephalic pancreatectomy had a 3.69 times higher risk of developing biliary leak (p=0.039; 95%CI:1.066, 1.181) and shorter survival compared to those undergoing palliative double bypass (p=0.022). No statistically significant association was found between the type of surgical procedure and other postoperative complications.</p><p><strong>Conclusion: </strong>Our study suggests that the double palliative bypass procedure may be a better option than R1 resection for patients with BRPHC.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 1","pages":"29-32"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10928687/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140121701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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