Journal of hazardous materials最新文献_第2页

Biochar-bacteria coupling system enhanced the bioremediation of phenol wastewater-based on life cycle assessment and environmental safety analysis. 基于生命周期评估和环境安全分析的生物炭-细菌耦合系统增强了苯酚废水的生物修复能力。

Journal of hazardous materials Pub Date : 2024-11-05 DOI: 10.1016/j.jhazmat.2024.136414

Xuejiao An, Yanlin Wang, Chenglong Yu, Xiaojing Hu

{"title":"Biochar-bacteria coupling system enhanced the bioremediation of phenol wastewater-based on life cycle assessment and environmental safety analysis.","authors":"Xuejiao An, Yanlin Wang, Chenglong Yu, Xiaojing Hu","doi":"10.1016/j.jhazmat.2024.136414","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136414","url":null,"abstract":"The efficient treatment of phenol wastewater is of great necessity since it induces serious pollution of water and soil ecosystems. Using biochar-immobilized functional microorganisms can innovatively and sustainably deal with the existing problem. In this study, we utilized response surface methodology (RSM) combined with life cycle assessment (LCA) to improve phenol biodegradation rate through a novel separated alkali-resistant and thermophilic strain Bacillus halotolerans ACY. Bioinformatic analysis revealed the genetic foundation of ACY to adapt to harsh environments. The characteristics of pig manure biochar (PMB) produced at varying pyrolysis temperatures (300-700 ℃) and adsorption experiment were investigated, immobilization of the phenol-degrading ACY on PMB600 under alkaline and high pollution load promoted phenol removal and extreme environment resistance, and the phenol removal rate reached 99.5 % in 7d in actual phenol wastewater, which increased compared with those achieved by PMB (50.6 %) and free bacteria (80.5 %) alone. Scanning Electron Microscope (SEM) and Fourier transform infrared spectrometry (FTIR) observations indicated the successful bacterial immobilization on PMB600. Reusability and economic cost study further demonstrated PMB600 as an excellent carrier for wastewater treatment. LC-MS, toxicology and carbon footprint analyses demonstrated that bacterial metabolism exerted synergy with adsorption for phenol removal, while biodegradation exerted the predominant impact on the immobilized bacterial system. This study provides an eco-friendly and effective approach to treat phenol wastewater.","PeriodicalId":94082,"journal":{"name":"Journal of hazardous materials","volume":"480 ","pages":"136414"},"PeriodicalIF":0.0,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antibiotic intermediates and antibiotics synergistically promote the development of multiple antibiotic resistance in antibiotic production wastewater. 抗生素中间体和抗生素会协同促进抗生素生产废水中多种抗生素耐药性的产生。

Journal of hazardous materials Pub Date : 2024-11-05 Epub Date: 2024-08-22 DOI: 10.1016/j.jhazmat.2024.135601

Sun Miao, Yanyan Zhang, Baochan Li, Xin Yuan, Cong Men, Jiane Zuo

{"title":"Antibiotic intermediates and antibiotics synergistically promote the development of multiple antibiotic resistance in antibiotic production wastewater.","authors":"Sun Miao, Yanyan Zhang, Baochan Li, Xin Yuan, Cong Men, Jiane Zuo","doi":"10.1016/j.jhazmat.2024.135601","DOIUrl":"10.1016/j.jhazmat.2024.135601","url":null,"abstract":"Antibiotic resistance (AR) is a major public health concern. Antibiotic intermediates (AIs) used in the production of semisynthetic antibiotics have the same bioactive structure as parent antibiotics and synthetic antibiotic production wastewater usually contains high concentrations of residual AIs; however, the effects of AIs and their interactive effects with antibiotics on the emergence of AR are unknown. In this study, antibiotic-sensitive E. coli K12 was exposed to five types of β-lactam AIs and their parent antibiotic ampicillin to analyze their impact on the evolution of multiple AR. The results indicated that AI 6-APA inhibits bacterial growth and stimulates the production of reactive oxygen species, as well as induces AR and antibiotic persistence like the parent antibiotic AMP. Combined exposure to 6-APA and AMP synergistically stimulated the induction of multiple AR and antibiotic persistence. The resistance mutation frequency increased up to 6.1 × 106-fold under combined exposure and the combination index reached 1326.5, indicating a strong synergy of 6-APA and AMP. Phenotypic and genotypic analyses revealed that these effects were associated with the overproduction of reactive oxygen species, enhanced stress response signatures, and activation of efflux pumps. These findings provide evidence and mechanistic insights into AR induction by AIs in antibiotic production wastewater.","PeriodicalId":94082,"journal":{"name":"Journal of hazardous materials","volume":"479 ","pages":"135601"},"PeriodicalIF":0.0,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142147098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Revealing the essence of anion ligands in regulating amorphous MnOx to activate peracetic acid for micropollutant removal. 揭示阴离子配体在调节无定形氧化锰活化过乙酸以去除微污染物方面的本质。

Journal of hazardous materials Pub Date : 2024-10-31 DOI: 10.1016/j.jhazmat.2024.136361

Yudan Dong, Si Sun, Yunzhe Zheng, Jiamei Liu, Peng Zhou, Zhaokun Xiong, Jing Zhang, Zhi-Cheng Pan, Chuan-Shu He, Bo Lai

{"title":"Revealing the essence of anion ligands in regulating amorphous MnOx to activate peracetic acid for micropollutant removal.","authors":"Yudan Dong, Si Sun, Yunzhe Zheng, Jiamei Liu, Peng Zhou, Zhaokun Xiong, Jing Zhang, Zhi-Cheng Pan, Chuan-Shu He, Bo Lai","doi":"10.1016/j.jhazmat.2024.136361","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136361","url":null,"abstract":"How the anion ligands of manganese precursors affect the catalytic activity of amorphous manganese oxides (MnOx) in Fenton-like process is poorly understood. Here, five amorphous MnOx synthesized by Mn(II) precursors with different ligands were characterized and adopted to activate peracetic acid (PAA) for bisphenol A (BPA) degradation. Although > 90 % BPA removal was achieved in the five MnOx/PAA processes via both adsorption and oxidation, the oxidation kobs greatly differentiates by the ligands types with the order of MnOx-N > MnOx-S > MnOx-Cl > MnOx-AA > MnOx-OA. Ligands types would affect the specific surface area of MnOx and their ability to adsorb BPA, however which is not the decisive factor in determining the contaminant oxidation efficiency. Multiple experimental results indicate that the generation of oxygen vacancies induced by the ligands alters the Mn(III)/Mn(IV) ratio, ultimately contributing to the different efficiency of BPA oxidation driven by the direct electron transfer mechanism. Moreover, amorphous MnOx holds the promise of practical applications in catalytic PAA of various micropollutants with good stability. This study advances the fundamental understanding of ligand-regulated amorphous MnOx-catalyzed PAA process.","PeriodicalId":94082,"journal":{"name":"Journal of hazardous materials","volume":"480 ","pages":"136361"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142565383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unique role of Mn(II) in enhancing electro-oxidation of organic pollutants on anodes with low oxygen evolution potential at low current density. 锰（II）在低电流密度、低氧进化电位的阳极上增强有机污染物电氧化作用的独特作用。

Journal of hazardous materials Pub Date : 2024-10-31 DOI: 10.1016/j.jhazmat.2024.136332

Erdan Hu, Yuhua Ye, Bing Wang, Hefa Cheng

{"title":"Unique role of Mn(II) in enhancing electro-oxidation of organic pollutants on anodes with low oxygen evolution potential at low current density.","authors":"Erdan Hu, Yuhua Ye, Bing Wang, Hefa Cheng","doi":"10.1016/j.jhazmat.2024.136332","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136332","url":null,"abstract":"This study systematically explored the role of Mn(II) in the removal of 4-chlorophenol (4-CP) by electro-oxidation (EO) employing anodes with low oxygen evolution potential (OEP), i.e., Ti/RuO2-IrO2, Ti/Pt, and Ti/Ti4O7, as well as anodes with high OEP, namely, Ti/PbO2, Ti/SnO2, and boron-doped diamond (Si/BDD). Mn(II) significantly promoted 4-CP removal on the anodes with low OEP at fairly low current density (0.04 to 1 mA/cm2), but had minimal to negative impact on those with high OEP. Cyclic voltammetry and X-ray photoelectron spectra revealed that Mn(II) was oxidized to Mn(III), then to Mn(IV) on the anodes with low OEP, whereas its was oxidized directly to Mn(IV) on those with high OEP. Deposition of manganese oxide on the anodes with low OEP suppressed oxygen evolution reaction (OER) in EO process, but enhanced OER on those with high OEP. Quenching and spectral results consistently indicated that Mn(III) and Mn(IV) were the primary species responsible for enhancing 4-CP removal on the anodes with low OEP. These findings provide mechanistic insights into the redox transformation of Mn(II) in EO and the theoretical basis for a novel strategy to boost pollutant degradation in EO systems using low OEP anodes through coupling with the redox chemistry of manganese.","PeriodicalId":94082,"journal":{"name":"Journal of hazardous materials","volume":"480 ","pages":"136332"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142565395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Catalytic membrane with dual-layer structure for ultrafast degradation of emerging contaminants in surface water treatment. 用于超快降解地表水处理中新出现污染物的双层结构催化膜。

Journal of hazardous materials Pub Date : 2024-10-31 DOI: 10.1016/j.jhazmat.2024.136333

Qieyuan Gao, Xinyao Jin, Xi Zhang, Junwei Li, Peng Liu, Peijie Li, Xinsheng Luo, Weijia Gong, Daliang Xu, Raf Dewil, Heng Liang, Bart Van der Bruggen

{"title":"Catalytic membrane with dual-layer structure for ultrafast degradation of emerging contaminants in surface water treatment.","authors":"Qieyuan Gao, Xinyao Jin, Xi Zhang, Junwei Li, Peng Liu, Peijie Li, Xinsheng Luo, Weijia Gong, Daliang Xu, Raf Dewil, Heng Liang, Bart Van der Bruggen","doi":"10.1016/j.jhazmat.2024.136333","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136333","url":null,"abstract":"The catalytic membrane-based oxidation-filtration process integrates physical separation and chemical oxidation, offering a highly efficient water purification strategy. However, the oxidation-filtration process is limited in practical applications due to the short residence time of milliseconds within the catalytic layer and the interference of coexisting organic pollutants in real water. Herein, a dual-layer membrane containing a top selective layer and a bottom catalytic layer was fabricated using an in situ co-casting method with a double-blade knife. Experimental results demonstrated that the selective layer rejected macromolecular organic pollutants, thereby alleviating their interference with bisphenol A (BPA) degradation. Concurrently, the catalytic layer activated peracetic acid oxidant and achieved a high BPA degradation exceeding 90 % in milliseconds with reactive oxygen species (especially •OH). The finite-element analysis confirmed a high-concentration reaction field occupying the pore cavity of the catalytic layer, enhancing collision probability between reactive oxygen species and BPA, i.e., the nano-confinement effect. Additionally, the dual-layer membrane achieved a long-term stable performance for emerging contaminant degradation in surface water treatment. This work underscores a novel catalytic membrane structure design for high-performance oxidation-filtration processes and elucidates its mechanisms underlying ultrafast degradation.","PeriodicalId":94082,"journal":{"name":"Journal of hazardous materials","volume":"480 ","pages":"136333"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142565379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phototransformation and photoreactivity of MPs-DOM in aqueous environment: Key role of MPs structure decoded by optical and molecular signatures. MPs-DOM 在水环境中的光转化和光活性：通过光学和分子特征解读 MPs 结构的关键作用。

Journal of hazardous materials Pub Date : 2024-10-31 DOI: 10.1016/j.jhazmat.2024.136331

Saisai Guo, Linan Liu, Lan Wang, Jingchun Tang

{"title":"Phototransformation and photoreactivity of MPs-DOM in aqueous environment: Key role of MPs structure decoded by optical and molecular signatures.","authors":"Saisai Guo, Linan Liu, Lan Wang, Jingchun Tang","doi":"10.1016/j.jhazmat.2024.136331","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136331","url":null,"abstract":"The dissolved organic matter (DOM) derived from microplastics (MPs-DOM) can be one of the photoactive components in DOM. However, information on the properties and photoreactivity of MPs-DOM during phototransformation is limited. Here, we investigated the properties and photoreactivity of MPs-DOM from polyolefins (MPs-DOM-POs), MPs-DOM derived from benzene-containing polymers (MPs-DOM-BCPs), and Suwannee River natural organic matter (SR-NOM), during a 168-hour phototransformation. After phototransformation, all examined types of DOM exhibit a decrease in concentration and molecular weight. Notably, MPs-DOM-POs display increased aromaticity and saturation, while MPs-DOM-BCPs and SR-NOM show reduced aromaticity and saturation. MPs-DOM-POs present higher steady-state concentrations of •OH but much lower steady-state concentrations of 1O2 than those of MPs-DOM-BCPs. In comparison, MPs-DOM produce more •OH but less 1O2 than SR-NOM. This study proposes that the diversification of aliphatic C─H bonds (arylation and carbonylation) by reactive intermediates (especially •OH) is the main pathway for MPs-DOM-POs phototransformation for the first time. On the other hand, the cleavage on the aromatic carboxylic acids by reactive intermediates (especially 1O2) is the main mechanism for MPs-DOM-BCPs and SR-NOM phototransformation. Our findings provide new insights into the phototransformation and photoreactivity of MPs-DOM and help to understand the potential risks of MPs in aqueous environment.","PeriodicalId":94082,"journal":{"name":"Journal of hazardous materials","volume":"480 ","pages":"136331"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142565380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

pH dependence of reactive oxygen species generation and pollutant degradation in Fe(II)/O₂/tripolyphosphate system. Fe(II)/O2/tripolyphosphate 系统中活性氧生成和污染物降解的 pH 值依赖性。

Journal of hazardous materials Pub Date : 2024-10-16 DOI: 10.1016/j.jhazmat.2024.136174

Chengwu Zhang, Anqi Yang, Bing Qin, Wei Zhao, Chuipeng Kong, Chuanyu Qin

{"title":"pH dependence of reactive oxygen species generation and pollutant degradation in Fe(II)/O2/tripolyphosphate system.","authors":"Chengwu Zhang, Anqi Yang, Bing Qin, Wei Zhao, Chuipeng Kong, Chuanyu Qin","doi":"10.1016/j.jhazmat.2024.136174","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136174","url":null,"abstract":"It has been reported that tripolyphosphate (TPP) can effectively enhance the activation of O2 by Fe(II) to remove organic pollutants in the environment. However, the influence of solution pH on the generation and conversion of reactive oxygen species (ROS) and their degradation of pollutants in the Fe(II)/O2/TPP system needs further investigation. In this study, we demonstrated that O2•- and •OH were the main ROS responsible for degradation in the system at different pH conditions, and their formation rates were calculated using a steady-state model. Experiments combined with density functional theory (DFT) calculations showed that the p-nitrophenol (PNP) degradation pathway in the Fe(II)/O2/TPP system is regulated by solution pH. Specifically, at pH = 3, the existence of Fe(II) in the solution is dominated by [Fe(II)(HTPP)2]2-, which leads to a rapid conversion from O2 and HO2• to generate •OH, and PNP is primarily oxidatively degraded. However, at pH = 5/7, [Fe(II)(TPP)2]4- is taking the lead with which O2•- is accumulated in the solution due to the slow conversion to •OH in this condition, and the PNP is mainly reductively degraded. This study proposes a new strategy to achieve the targeted oxidative/reductive removal of different types of pollutants by simply varying the solution pH in the Fe(II)/O2/TPP system.","PeriodicalId":94082,"journal":{"name":"Journal of hazardous materials","volume":"480 ","pages":"136174"},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hot spots of resistance: Transit centers as breeding grounds for airborne ARG-carrying bacteriophages. 抗药性的热点：转运中心是空气中携带 ARG 的噬菌体的滋生地。

Journal of hazardous materials Pub Date : 2024-10-16 DOI: 10.1016/j.jhazmat.2024.136165

Jing Zhang, Jiayu Shang, Beibei Liu, Dong Zhu, Qinfen Li, Li Yin, Okugbe Ebiotubo Ohore, Shaobai Wen, Changfeng Ding, Yican Zhang, Zhengfu Yue, Yukun Zou

{"title":"Hot spots of resistance: Transit centers as breeding grounds for airborne ARG-carrying bacteriophages.","authors":"Jing Zhang, Jiayu Shang, Beibei Liu, Dong Zhu, Qinfen Li, Li Yin, Okugbe Ebiotubo Ohore, Shaobai Wen, Changfeng Ding, Yican Zhang, Zhengfu Yue, Yukun Zou","doi":"10.1016/j.jhazmat.2024.136165","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136165","url":null,"abstract":"The presence of pathogenic bacteria and antibiotic resistance genes (ARGs) in urban air poses a significant threat to public health. While prevailing research predominantly focuses on the airborne transmission of ARGs by bacteria, the potential influence of other vectors, such as bacteriophages, is often overlooked. This study aims to investigate the characteristics of phages and ARGs in aerosols originating from hospitals, public transit centers, wastewater treatment plants, and landfill sites. The average abundance of ARGs carried by phages in the public transit centers was 8.81 ppm, which was 2 to 3 times higher than that at the other three sites. Additionally, the abundance of ARGs across different risk levels at this site was also significantly higher than at the other three sites. The assembled phage communities bearing ARGs in public transit centers are chiefly governed by homogeneous selection processes, likely influenced by human movement. Furthermore, observations at public transit sites revealed that the average abundance ratio of virulent phages to their hosts was 1.01, and the correlation coefficient between their auxiliary metabolic genes and hosts' metabolic genes was 0.59, which were 20 times and 3 times higher, respectively, than those of temperate phages. This suggests that virulent phages may enhance their survival by altering host metabolism, thereby aiding the dispersion of ARGs and bacterial resistance. These revelations furnish fresh insights into phage-mediated ARG transmission, offering scientific substantiation for strategies aimed at preventing and controlling resistance within aerosols.","PeriodicalId":94082,"journal":{"name":"Journal of hazardous materials","volume":"480 ","pages":"136165"},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antibiotic resistance at environmental multi-media interfaces through integrated genotype and phenotype analysis. 通过基因型和表型综合分析研究环境多媒体界面的抗生素耐药性。

Journal of hazardous materials Pub Date : 2024-10-15 DOI: 10.1016/j.jhazmat.2024.136160

Chen-Xi Fu, Chen Chen, Qian Xiang, Yi-Fei Wang, Lu Wang, Feng-Yuan Qi, Dong Zhu, Hong-Zhe Li, Li Cui, Wei-Li Hong, Matthias C Rillig, Yong-Guan Zhu, Min Qiao

{"title":"Antibiotic resistance at environmental multi-media interfaces through integrated genotype and phenotype analysis.","authors":"Chen-Xi Fu, Chen Chen, Qian Xiang, Yi-Fei Wang, Lu Wang, Feng-Yuan Qi, Dong Zhu, Hong-Zhe Li, Li Cui, Wei-Li Hong, Matthias C Rillig, Yong-Guan Zhu, Min Qiao","doi":"10.1016/j.jhazmat.2024.136160","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136160","url":null,"abstract":"Antibiotic resistance is currently an unfolding global crisis threatening human health worldwide. While antibiotic resistance genes (ARGs) are known to be pervasive in environmental media, the occurrence of antibiotic resistance at interfaces between two or more adjacent media is largely unknown. Here, we designed a microcosm study to simulate plastic pollution in paddy soil and used a novel method, stimulated Raman scattering coupled with deuterium oxide (D2O) labelling, to compare the antibiotic resistance in a single medium with that at the interface of multiple environmental media (plastic, soil, water). Results revealed that the involvement of more types of environmental media at interfaces led to a higher proportion of active resistant bacteria. Genotypic analysis showed that ARGs (especially high-risk ARGs) and mobile genetic elements (MGEs) were all highly enriched at the interfaces. This enrichment was further enhanced by the co-stress of heavy metal (arsenic) and antibiotic (ciprofloxacin). Our study is the first to apply stimulated Raman scattering to elucidate antibiotic resistance at environmental interfaces and reveals novel pathway of antibiotic resistance dissemination in the environment and overlooked risks to human health.","PeriodicalId":94082,"journal":{"name":"Journal of hazardous materials","volume":"480 ","pages":"136160"},"PeriodicalIF":0.0,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polystyrene nanoplastics enhance thrombosis through adsorption of plasma proteins. 聚苯乙烯纳米塑料通过吸附血浆蛋白促进血栓形成。

Journal of hazardous materials Pub Date : 2024-10-15 DOI: 10.1016/j.jhazmat.2024.136168

Chao Sheng, Guozhen Wang, Zijia Liu, Yuchen Zheng, Zijie Zhao, Duo Tang, Wenzhuo Li, Ao Li, Qi Zong, Renhang Zhou, Xiaonan Hou, Mengfei Yao, Zhixiang Zhou

{"title":"Polystyrene nanoplastics enhance thrombosis through adsorption of plasma proteins.","authors":"Chao Sheng, Guozhen Wang, Zijia Liu, Yuchen Zheng, Zijie Zhao, Duo Tang, Wenzhuo Li, Ao Li, Qi Zong, Renhang Zhou, Xiaonan Hou, Mengfei Yao, Zhixiang Zhou","doi":"10.1016/j.jhazmat.2024.136168","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136168","url":null,"abstract":"Plastic products offer remarkable convenience for modern life. However, growing concerns are emerging regarding the potential health hazards posed by nanoplastics, which formed as plastics break down. Currently, the biological effects and mechanisms induced by nanoplastics are largely underexplored. In this study, we report that polystyrene nanoplastics can enter the bloodstream and enhance thrombus formation. Our findings show that polystyrene nanoplastics adsorb plasma proteins, particularly coagulation factor XII and plasminogen activator inhibitor-1, play a key role in this process, as demonstrated by proteomics, bioinformatic analyses, and molecular dynamics simulations. The adsorption of these proteins by nanoplastics is an essential factor in thrombosis enhancement. This newly uncovered pathway of protein adsorption leading to enhanced thrombosis provides new insights into the biological effects of nanoplastics, which may inform future safety and environmental risk assessment of plastics.","PeriodicalId":94082,"journal":{"name":"Journal of hazardous materials","volume":"480 ","pages":"136168"},"PeriodicalIF":0.0,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0