{"title":"[Unusual manifestation of varicose veins: a 69-year-old patient with finger pain].","authors":"Frank Stammler, Marion Wenzler","doi":"10.1055/a-2506-6795","DOIUrl":"https://doi.org/10.1055/a-2506-6795","url":null,"abstract":"<p><p>Varicose veins of the hand and fingers are an unusual presentation and are little known in the consultation as a differential diagnosis of hand complaints.A 69-year-old female patient, who had worked as a cleaner for a long time, presented to our practice because of pain in the palm of her hand. She had been observing bluish changes on the volar side of the hand and fingers for more than 10 years. A few days ago, painful nodules had appeared on the middle and ring fingers of her right hand.The clinical examination revealed the suspicion of an extensive palmar hand and finger varicosis on both sides, with indurated nodules on D3 and 4 on the right, which was confirmed by duplex sonography as partially thrombosed finger varices. The varicose vein thrombosis developed under anticoagulation with Rivaroxaban 20mg, which was indicated due to atrial fibrillation.Analgesia with 600-1200mg Ibuprofen led to a rapid regression of pain. Remedial treatment options for finger varicosis such as sclerotherapy, ablative procedures or surgical excision were discussed as experimental approaches and were not desired by the patient.Unlike in the lower extremities, hands and fingers are less well-known manifestations of varicosis. Finger varicosis usually appears asymptomatically, but can cause pain if finger hematomas and variceal thrombosis occur. Varicose veins of the hand occur more frequently in aged patients and are favored by mechanical stress. Treatment is usually symptomatic.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 10","pages":"571-574"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144003767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Obesity in intensive care].","authors":"Michael Haap","doi":"10.1055/a-2286-6542","DOIUrl":"https://doi.org/10.1055/a-2286-6542","url":null,"abstract":"<p><p>The prevalence of obesity and its associated comorbidities are increasing worldwide, leading to a rising proportion of obese patients in hospitals and intensive care units. This trend is causing a significant additional burden on our healthcare system. An obese patient requiring intensive care treatment presents major challenges for the entire team, not only in terms of economic aspects but also medically, in nursing care, and in physiotherapy. Additionally, psychosocial and organizational factors play a role that must be considered. For nursing and physiotherapy, appropriate aids such as lifters, special large hospital beds, suitable rooms, and adequate staffing should be provided. The medical challenges include intubation and airway management, hemodynamic monitoring, vascular access, adequate nutrition, appropriate dosing of medication, and difficult ultrasound conditions at the bedside. Furthermore, this patient population has an increased risk of developing pressure ulcers, pneumonia, and thrombosis, which increase the overall care requirements and further challenge the intensive care setting.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 11","pages":"632-644"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144046146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Generation X and millennials are at greater cancer risk than previous generations: Possible causes and implications].","authors":"Hans Scherübl","doi":"10.1055/a-2531-9761","DOIUrl":"https://doi.org/10.1055/a-2531-9761","url":null,"abstract":"<p><p>The incidence of early-onset malignancy (EOM) diagnosed under the age of 50 has been increasing worldwide. In the USA, Generation X and the millennials are up to 2 times more likely to develop 17 of the 34 most common cancers than the baby boomers at any given age. Globally, the incidence of EOM increased by 79.1% between 1990 and 2019. Early-life exposure may be linked with EOM development and may forecast a greater disease burden in the future. Possible causes and consequences are discussed with regards to cancer prevention.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 10","pages":"575-583"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Diagnostic of the chronic coronary syndrome].","authors":"Katharina A Riedl, Renate Schnabel","doi":"10.1055/a-2463-2902","DOIUrl":"https://doi.org/10.1055/a-2463-2902","url":null,"abstract":"<p><p>The chronic coronary syndrome can be attributed to different pathophysiological epicardial or microvascular mechanisms. In the current ESC guideline from 2024, a diagnostic algorithm was developed based on a risk-factor-weighted individual pre-test probability. The baseline diagnostic includes anamnesis, electrocardiogram, and a laboratory chemical analysis, especially to exclude an acute coronary syndrome. The early and direct assessments for risk-factor-weighted individual pre-test probability are calculated by taking into account clinical symptoms, individual cardiovascular risk factors, age, and gender. Resting ECG, echocardiography and the evaluation of the peripheral arteries and data on possible known vascular calcifications in previous imaging examinations can further adjust and modify the pre-test probability. Non-invasive imaging methods (computed tomography angiography, magnetic resonance imaging, stress echocardiography, SPECT, PET) or invasive coronary angiography can be used to confirm or exclude the diagnosis of chronic coronary syndrome.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 11","pages":"607-614"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144014998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Invasive treatment of chronic coronary syndrome].","authors":"Julinda Mehilli, Arben Perani","doi":"10.1055/a-2430-0255","DOIUrl":"https://doi.org/10.1055/a-2430-0255","url":null,"abstract":"<p><p>The 2024 guidelines of the European Society of Cardiology for the treatment of chronic coronary syndrome provide a comprehensive overview covering prevention, diagnostics, as well as pharmacological and invasive therapies. Based on the latest scientific evidence, the guidelines for myocardial revascularization, valid since 2018, have been updated, and treatment recommendations have been adjusted accordingly. Myocardial revascularization, as an adjunct to optimal pharmacological therapy, remains a key treatment strategy for symptom relief, as well as for improving quality of life and long-term clinical outcomes in patients with chronic coronary syndrome. The decision between percutaneous coronary intervention and coronary artery bypass surgery depends on the anatomical complexity and functional severity of coronary artery disease, as well as comorbidities, patient preferences, and expectations. A careful risk-benefit assessment and an individualized treatment approach are essential to ensure optimal care for each patient. The current guidelines provide an evidence-based framework for this complex decision-making process.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 11","pages":"623-627"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143995134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Adjuvant and neoadjuvant therapy of melanoma].","authors":"Dirk Debus, Axel Hauschild, Erwin S Schultz","doi":"10.1055/a-2453-8887","DOIUrl":"https://doi.org/10.1055/a-2453-8887","url":null,"abstract":"<p><p>The treatment of malignant melanoma with (neo-)adjuvant therapy represents a promising approach to reducing recurrence and metastasis. At the same time, due to the risk of potential side effects, a risk-benefit assessment is required in advance, taking into account the stage-dependent risk of recurrence. The article presents the current study situation on adjuvant and neoadjuvant therapy.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 10","pages":"555-561"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[68-year-old patient with pain of the left hip und thigh].","authors":"Oanh Vo, Philipp Klemm, Nils Schulz","doi":"10.1055/a-2497-3686","DOIUrl":"https://doi.org/10.1055/a-2497-3686","url":null,"abstract":"","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 10","pages":"545-546"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}