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[Diagnosis and treatment of thyroid dysfunction associated with amiodarone]. [胺碘酮相关甲状腺功能障碍的诊断与治疗]。
IF 0.7
Deutsche medizinische Wochenschrift (1946) Pub Date : 2026-05-01 Epub Date: 2026-03-20 DOI: 10.1055/a-2735-3729
Jonas Schnider, Matthias Auer, Eleni Pappa
{"title":"[Diagnosis and treatment of thyroid dysfunction associated with amiodarone].","authors":"Jonas Schnider, Matthias Auer, Eleni Pappa","doi":"10.1055/a-2735-3729","DOIUrl":"10.1055/a-2735-3729","url":null,"abstract":"<p><strong>Abstract: </strong>Amiodarone, a potent antiarrhythmic drug, may cause thyroid dysfunction due to its high iodine content. Both hypo- and hyperthyroidism can occur. Early diagnosis, differentiation of subtypes, and individualized therapy are essential to prevent severe complications and improve patient outcomes.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":" ","pages":"510-518"},"PeriodicalIF":0.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147492420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Carotid stenosis]. (颈动脉狭窄)。
IF 0.7
Deutsche medizinische Wochenschrift (1946) Pub Date : 2026-05-01 Epub Date: 2026-05-04 DOI: 10.1055/a-2727-7312
Christine Espinola-Klein
{"title":"[Carotid stenosis].","authors":"Christine Espinola-Klein","doi":"10.1055/a-2727-7312","DOIUrl":"https://doi.org/10.1055/a-2727-7312","url":null,"abstract":"","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"151 10","pages":"469"},"PeriodicalIF":0.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147847844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[STIKO Recommendation: MF59-Adjuvanted Influenza Vaccine for Individuals ≥ 60 Years of Age]. [STIKO建议：mf59佐剂流感疫苗适用于≥60岁的个体]。
IF 0.7
Deutsche medizinische Wochenschrift (1946) Pub Date : 2026-05-01 Epub Date: 2026-05-04 DOI: 10.1055/a-2812-2784
Martina Prelog, Barbara Gärtner, Andreas Leischker, Christina Rieger, Ralf-Peter Vonberg, Tino F Schwarz
{"title":"[STIKO Recommendation: MF59-Adjuvanted Influenza Vaccine for Individuals ≥ 60 Years of Age].","authors":"Martina Prelog, Barbara Gärtner, Andreas Leischker, Christina Rieger, Ralf-Peter Vonberg, Tino F Schwarz","doi":"10.1055/a-2812-2784","DOIUrl":"https://doi.org/10.1055/a-2812-2784","url":null,"abstract":"<p><strong>Abstract: </strong>In October 2024, the Standing Committee on Vaccination (STIKO) adjusted its recommendation on seasonal influenza vaccination for people aged 60 and over. Based on new study data, the MF59-adjuvanted influenza vaccine is now recommended as equivalent to the high-dose vaccine: The MF59-adjuvanted vaccine was shown to be superior in terms of effectiveness compared to non-adjuvanted standard vaccines in older adults. The immune response to the adjuvanted vaccine was broader and stronger than to the standard vaccine. The MF59-adjuvanted vaccine had a similar safety profile to the high-dose vaccine, both showing slightly increased local and systemic reactogenicity compared to the standard vaccine. STIKO believes that recommending both vaccines could increase acceptance and willingness to be vaccinated in the target population.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"151 10","pages":"501-508"},"PeriodicalIF":0.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147846980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Interventional Therapy for Extracranial Carotid Stenosis]. 颈动脉颅外狭窄的介入治疗
IF 0.7
Deutsche medizinische Wochenschrift (1946) Pub Date : 2026-05-01 Epub Date: 2026-05-04 DOI: 10.1055/a-2749-4230
Martin Andrassy, Ralf Langhoff, Grigorios Korosoglou
{"title":"[Interventional Therapy for Extracranial Carotid Stenosis].","authors":"Martin Andrassy, Ralf Langhoff, Grigorios Korosoglou","doi":"10.1055/a-2749-4230","DOIUrl":"https://doi.org/10.1055/a-2749-4230","url":null,"abstract":"<p><strong>Abstract: </strong>Surgical and endovascular procedures are established treatments for extracranial stenoses of the internal carotid artery (ICA) according to current guidelines. Revascularization is generally recommended for symptomatic ICA stenoses between 50% and 99%. For asymptomatic stenoses, optimal medical therapy is the primary focus; revascularization should be considered for stenoses between 60% and 99%, depending on the individual risk. The choice between endarterectomy (CEA) and carotid artery stent implantation (CAS) is made by an interdisciplinary team, considering patient- and anatomy-specific factors. Interventional therapy is well-established; however, studies show an increased incidence of minor strokes and transient ischemic attacks (TIAs), which is why patient selection and embolic protection are becoming increasingly important in the field of endovascular revascularization. Technological advancements, such as innovative double-layer stents for improved plaque coverage, increase the safety of the procedure, and reduce the peri-procedural stroke rate. Anatomical features are essential for successful treatment when selecting devices and planning procedures.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"151 10","pages":"491-499"},"PeriodicalIF":0.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147847837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Surgical treatment of extracranial carotid stenosis]. 颈动脉颅外狭窄的外科治疗。
IF 0.7
Deutsche medizinische Wochenschrift (1946) Pub Date : 2026-05-01 Epub Date: 2026-05-04 DOI: 10.1055/a-2672-8257
Hanna Schlichting, Franziska Heidemann, Christian-Alexander Behrendt
{"title":"[Surgical treatment of extracranial carotid stenosis].","authors":"Hanna Schlichting, Franziska Heidemann, Christian-Alexander Behrendt","doi":"10.1055/a-2672-8257","DOIUrl":"https://doi.org/10.1055/a-2672-8257","url":null,"abstract":"<p><strong>Abstract: </strong>Invasive treatment of carotid stenosis is directed towards the prevention of ischemic stroke. Contemporary guidelines, based on the best available evidence, recommend carotid endarterectomy for symptomatic carotid stenosis of 50-99%. Revascularization should ideally be performed within 48 hours to 14 days following the index ischemic event. In asymptomatic patients, intervention is indicated in the presence of clinical or morphological markers associated with an increased risk of carotid stenosis-related stroke. Carotid artery stenting represents a complementary alternative to endarterectomy, particularly in patients at high surgical risk. Given that several recommendations are based on expert opinion rather than high-level evidence, interdisciplinary decision-making plays a crucial role. Patients with limited life expectancy should not undergo invasive treatment; all patients with carotid artery disease should receive optimal medical therapy.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"151 10","pages":"483-490"},"PeriodicalIF":0.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147847042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[General practitioner consultation on advance directives - results of a survey of general practitioners in Lower Saxony]. [全科医生对预先指示的咨询-对下萨克森州全科医生的调查结果]。
IF 0.7
Deutsche medizinische Wochenschrift (1946) Pub Date : 2026-05-01 Epub Date: 2026-05-04 DOI: 10.1055/a-2812-4629
Malte Klemmt, Katharina van Baal, Maria Bonin, Carolin Fleischmann, Silke Neuderth, Tanja Henking, Stephanie Stiel
{"title":"[General practitioner consultation on advance directives - results of a survey of general practitioners in Lower Saxony].","authors":"Malte Klemmt, Katharina van Baal, Maria Bonin, Carolin Fleischmann, Silke Neuderth, Tanja Henking, Stephanie Stiel","doi":"10.1055/a-2812-4629","DOIUrl":"https://doi.org/10.1055/a-2812-4629","url":null,"abstract":"<p><strong>Background: </strong>Although medical consultation is not mandatory when drawing up living wills, it is recommended. General practitioners (GPs) can be suitable contact persons for drawing up and updating advance directive documents. The aim of this study is to record the frequency and type of GP counselling on advance directive documents. It also aims to record the subjective level of competence and knowledge of GPs with regard to counselling on advance directive documents.</p><p><strong>Method: </strong>An online survey was conducted between October and November 2024. The target group was all general practitioners practising in Lower Saxony. An adapted version of a field-tested questionnaire was used, including a case vignette-based knowledge test on advance care planning documents. The data were evaluated using descriptive and inferential statistics.</p><p><strong>Results: </strong>Data from 502 GPs were included. 85.1% of respondents stated that they advise their patients on advance directive documents. Reasons for not counselling patients include a lack of need of patients or a lack of qualification of GPs. The participants rated their subjective counselling competence as rather high. Uncertainties were reported in dealing with patients' emotions and fears. The objective knowledge test showed an average score of 22.5 out of a possible 30 points. A high level of knowledge was particularly evident in relation to the conditions for the effectiveness of living wills. There are knowledge gaps in the area of representation law.</p><p><strong>Discussion: </strong>The majority of GPs surveyed counsel patients on advance directive documents. However, there are clear knowledge gaps and uncertainties that may influence the quality of counselling.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"151 10","pages":"e23-e33"},"PeriodicalIF":0.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13138853/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147847805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Diagnosis and conservative treatment of carotid artery stenosis]. 颈动脉狭窄的诊断与保守治疗。
IF 0.7
Deutsche medizinische Wochenschrift (1946) Pub Date : 2026-05-01 Epub Date: 2026-05-04 DOI: 10.1055/a-2666-3494
Marianne Hahn, Klaus Gröschel
{"title":"[Diagnosis and conservative treatment of carotid artery stenosis].","authors":"Marianne Hahn, Klaus Gröschel","doi":"10.1055/a-2666-3494","DOIUrl":"https://doi.org/10.1055/a-2666-3494","url":null,"abstract":"<p><strong>Abstract: </strong>Carotid artery stenosis is a major cause of ischemic stroke, with prevalence increasing with age and vascular risk factors. Targeted diagnosis in patients with acute cerebrovascular disease and high-risk populations, combined with consistent conservative management, is essential to significantly reduce stroke risk. This article reviews current diagnostic strategies, including duplex ultrasound as the cornerstone of non-invasive assessment, and discusses pharmacological and non-pharmacological treatment approaches. Medical therapy-including antiplatelet therapy, statins, and vascular risk factor control-is crucial across all stenosis stages and may suffice even in some cases traditionally considered for revascularization. Current research focuses on individualized therapy guided by risk stratification to identify patients for whom conservative management alone provides optimal stroke prevention. Interdisciplinary decision-making is essential to tailor treatment strategies.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"151 10","pages":"477-482"},"PeriodicalIF":0.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147847832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Characterization of imported dengue fever cases in Germany - Results of a pilot project]. [德国输入性登革热病例的特征-试点项目的结果]。
IF 0.7
Deutsche medizinische Wochenschrift (1946) Pub Date : 2026-04-21 DOI: 10.1055/a-2828-3673
Mia Wintel, Julian Bernhard, Julia S Beck, Andre Fuchs, Frank Tobian, Andreas K Lindner, Frank P Mockenhaupt, Claudia M Denkinger
{"title":"[Characterization of imported dengue fever cases in Germany - Results of a pilot project].","authors":"Mia Wintel, Julian Bernhard, Julia S Beck, Andre Fuchs, Frank Tobian, Andreas K Lindner, Frank P Mockenhaupt, Claudia M Denkinger","doi":"10.1055/a-2828-3673","DOIUrl":"https://doi.org/10.1055/a-2828-3673","url":null,"abstract":"<p><strong>Background: </strong>Dengue fever is a mosquito-borne viral infectious disease with an estimated 100-400 million infections worldwide every year. The currently highest case numbers are also reflected in the specialized centers in Germany. A pilot project for the surveillance of highly infectious imported diseases at the tropical medicine centers in Berlin, Heidelberg and Augsburg used dengue fever to pilot joint data collection, transmission and analysis.</p><p><strong>Methods: </strong>Patients with dengue fever were included in the survey. Demographic, anamnestic and clinical-laboratory data were recorded and then transferred to an online database (RedCap) accessible to all participating centers.</p><p><strong>Results: </strong>In the pilot phase (August to December 2023) 42 patients were included (median age: 35.5 years; travel duration: median 20 days). The countries of infection were South (East) Asia (64.3%), Central America (30.9%) and Africa (4.8%). The mostly classic symptoms (fever, headache, joint and muscle pain, exanthema) began during the trip in almost two thirds of cases. The diagnosis was based on the detection of the NS1 antigen in 71.4% and on serology in 28.6%. The piloted system proved to be practicable for detecting infectious threats in terms of pandemic preparedness.</p><p><strong>Conclusion: </strong>The joint detection of an infectious disease was successfully piloted. Dengue fever presented itself in its classic form. Growing case numbers and the risk of autochthonous transmission are increasingly bringing dengue fever into the focus of differential diagnosis in Germany.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147792790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The pregnant patient in the Emergency Department]. [急诊科的孕妇]。
IF 0.7
Deutsche medizinische Wochenschrift (1946) Pub Date : 2026-04-01 Epub Date: 2026-04-02 DOI: 10.1055/a-2593-7160
Christoph Dodt
{"title":"[The pregnant patient in the Emergency Department].","authors":"Christoph Dodt","doi":"10.1055/a-2593-7160","DOIUrl":"https://doi.org/10.1055/a-2593-7160","url":null,"abstract":"<p><p>Emergency physicians must be familiar with the basics of treating pregnant women and pregnancy-related emergencies. Pregnant women who present at an emergency department are usually victims of accidents. Others suffer from illnesses that are not directly related to pregnancy. Quite a few women of childbearing age are surprised to learn that they are pregnant during the diagnostic process.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"151 8","pages":"369-376"},"PeriodicalIF":0.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[A 34-year-old female patient with a cystic pancreatic lesion]. 34岁女性胰腺囊性病变患者。
IF 0.7
Deutsche medizinische Wochenschrift (1946) Pub Date : 2026-04-01 Epub Date: 2026-04-02 DOI: 10.1055/a-2790-3651
Clemens Rommel, Maximilian von Laffert, Thomas Karlas
{"title":"[A 34-year-old female patient with a cystic pancreatic lesion].","authors":"Clemens Rommel, Maximilian von Laffert, Thomas Karlas","doi":"10.1055/a-2790-3651","DOIUrl":"https://doi.org/10.1055/a-2790-3651","url":null,"abstract":"","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"151 8","pages":"359-360"},"PeriodicalIF":0.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147611092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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