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Deutsche medizinische Wochenschrift (1946)最新文献

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[Exercise-induced dyspnea in neurofibromatosis, what could be the cause?] 运动引起的神经纤维瘤病呼吸困难，可能是什么原因？］
Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-07-01 Epub Date: 2025-06-25 DOI: 10.1055/a-2606-5719
Sarah S Schiesser, Urs Eriksson, Ann-Katrin Rodewald, Michael Huber
{"title":"[Exercise-induced dyspnea in neurofibromatosis, what could be the cause?]","authors":"Sarah S Schiesser, Urs Eriksson, Ann-Katrin Rodewald, Michael Huber","doi":"10.1055/a-2606-5719","DOIUrl":"https://doi.org/10.1055/a-2606-5719","url":null,"abstract":"","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 14","pages":"826-830"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144499900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
["Accompanying the dying process" - A guide to dealing with the dying and their relatives]. [“陪伴死亡的过程”-处理临终者及其亲属的指南]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-07-01 Epub Date: 2025-06-25 DOI: 10.1055/a-2436-7825
Daniela Tölle, Marion Ferner, Sandra Stephanie Mai, Ulrike Reinholz
{"title":"[\"Accompanying the dying process\" - A guide to dealing with the dying and their relatives].","authors":"Daniela Tölle, Marion Ferner, Sandra Stephanie Mai, Ulrike Reinholz","doi":"10.1055/a-2436-7825","DOIUrl":"https://doi.org/10.1055/a-2436-7825","url":null,"abstract":"<p><p>Recognizing the dying phase is often a major challenge for professional carers. The associated adaption of medical and nursing measures and knowledge of options for drug and non-drug symptom control, including off-lable-use (OLU), are the basis of care for the dying. Treating the dying also always means caring for the informal carers as a unit of care. With the help of a multi-professional team, it is possible to meet the needs of patients and their family caregivers in all dimensions of a human being. Meeting the existential needs of the dying and their relatives requires a benevolent attitude on the part of those treating them, an awareness of the importance of communication and a willingness to accept dying. When patients are preparing to die, we can take their wishes into account, such as the place of death.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 14","pages":"807-816"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144499897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[82-year-old patient with severe vomiting after eating spoiled fish]. [82岁患者食用变质鱼后严重呕吐]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-07-01 Epub Date: 2025-06-25 DOI: 10.1055/a-2522-9805
Klaus Muehlenberg, Lukas Pfeifer, Oliver Pech
{"title":"[82-year-old patient with severe vomiting after eating spoiled fish].","authors":"Klaus Muehlenberg, Lukas Pfeifer, Oliver Pech","doi":"10.1055/a-2522-9805","DOIUrl":"https://doi.org/10.1055/a-2522-9805","url":null,"abstract":"","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 14","pages":"797-798"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144499898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Palliative medicine]. 姑息医学。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-07-01 Epub Date: 2025-06-25 DOI: 10.1055/a-2436-7682
Claudia Bausewein
{"title":"[Palliative medicine].","authors":"Claudia Bausewein","doi":"10.1055/a-2436-7682","DOIUrl":"https://doi.org/10.1055/a-2436-7682","url":null,"abstract":"","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 14","pages":"787"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144499903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Outpatient palliative care for non-oncological diseases]. [非肿瘤疾病的门诊姑息治疗]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-07-01 Epub Date: 2025-06-25 DOI: 10.1055/a-2436-7791
Paul Wiesheu, Ulrich Grabenhorst, Johannes Maximilian Just
{"title":"[Outpatient palliative care for non-oncological diseases].","authors":"Paul Wiesheu, Ulrich Grabenhorst, Johannes Maximilian Just","doi":"10.1055/a-2436-7791","DOIUrl":"https://doi.org/10.1055/a-2436-7791","url":null,"abstract":"<p><p>The primary function of outpatient palliative care is to empower patients with life-threatening illnesses to optimize their quality of life by maximising their independence in their own home environment. In addition to addressing oncological diseases, the attention for palliative care towards non-oncological diseases is growing, a trend that is especially relevant for outpatient care. The early identification of the need for palliative care is of critical importance, as is the provision of effective palliative care within appropriate structures.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 14","pages":"799-806"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144499902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Genetic Causes of Heart Failure in Adults]. [成人心力衰竭的遗传原因]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-07-01 Epub Date: 2025-06-25 DOI: 10.1055/a-2304-7182
Brenda Gerull
{"title":"[Genetic Causes of Heart Failure in Adults].","authors":"Brenda Gerull","doi":"10.1055/a-2304-7182","DOIUrl":"10.1055/a-2304-7182","url":null,"abstract":"<p><p>Genetic factors play a pivotal role in personalized care for heart failure. This article explores hereditary cardiomyopathies, a heterogeneous group of genetic heart muscle disorders, representing a major cause of heart failure. They are classified into distinct clinical phenotypes: hypertrophic (HCM), dilated (DCM), non-dilated left ventricular (NDLVC), arrhythmogenic right ventricular (ARVC), and restrictive cardiomyopathy (RCM). Diagnosis integrates a multiparametric approach, including clinical evaluation, electrocardiography, advanced imaging, and genetic testing. Genetic counselling and testing are recommended for precise subtyping, prognosis, and therapy guidance. Family cascade screening is critical due to variable penetrance and age-dependent clinical expression, identifying asymptomatic carriers and reducing follow-up burden in low-risk relatives. High-risk genotypes require individualized risk stratification, particularly for life-threatening arrhythmias and sudden cardiac death. Emerging genotype-specific strategies are advancing precision medicine.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 14","pages":"831-844"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144499901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Basic knowledge of drug pain therapy in the palliative situation]. 【姑息情况下药物疼痛治疗的基本知识】。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-07-01 Epub Date: 2025-06-25 DOI: 10.1055/a-2544-4239
Sascha Weber, Angelika Lampert, Julia C Stingl, Vera Peuckmann-Post, Sonja Hiddemann, Frank Elsner, Irene Neuner, Roman Rolke
{"title":"[Basic knowledge of drug pain therapy in the palliative situation].","authors":"Sascha Weber, Angelika Lampert, Julia C Stingl, Vera Peuckmann-Post, Sonja Hiddemann, Frank Elsner, Irene Neuner, Roman Rolke","doi":"10.1055/a-2544-4239","DOIUrl":"https://doi.org/10.1055/a-2544-4239","url":null,"abstract":"<p><p>This review provides an overview of the basic knowledge of drug pain therapy in the palliative situation. Pain is one of the main symptoms in 60 to 90% of cancer patients. Pain also develops with neurological and other diseases that occur in end-of-life situations. To address this symptom, a holistic strategy is required that encompasses all physical, psychological, social, and spiritual aspects of the multi-dimensional pain experience (\"total pain\" concept).Drug treatment for cancer pain has been based on a stepwise approach for many years, starting with non-opioid analgesics, followed by moderate and strong opioids. In contrast, today's pain management is determined more by the actual intensity of this aversive event.The pain assessment should be tailored to identify a nociceptive vs. a neuropathic pain component that needs to be challenged by the most appropriate drug therapies. Non-opioid analgesics are ideal substances for relieving nociceptive pain. Antidepressants and anticonvulsants reduce the intensity of new neuropathic pain. Opioids are suitable for all types of pain, but are restricted to a second-line choice. Among all opioids are Tilidine and Tramadol prodrugs, which only relieve pain after activation in the liver. Drug-drug interactions may also block this activation. Rapid release opioids should be used for break-through cancer pain. Transdermal opioid applications are recommended in case of swallowing disorders, but usually not to initiate pain control. An opioid change can be performed if side effects such as hallucinations for the selected opioid are more pronounced than the pain reduction.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 14","pages":"817-825"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144499899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Antithrombotic therapy for polyvascular atherosclerosis]. [多血管粥样硬化的抗血栓治疗]。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-06-01 Epub Date: 2025-05-28 DOI: 10.1055/a-2359-4422
Christine Espinola-Klein
{"title":"[Antithrombotic therapy for polyvascular atherosclerosis].","authors":"Christine Espinola-Klein","doi":"10.1055/a-2359-4422","DOIUrl":"https://doi.org/10.1055/a-2359-4422","url":null,"abstract":"<p><p>Patients with polyvascular atherosclerosis are twice as likely to have cardiovascular events as patients with monovascular atherosclerosis. Anticoagulant therapy improves the prognosis and is therefore clearly recommended. Intensified anticoagulation is more effective in reducing risk but is associated with a higher risk of bleeding. Compared to patients with monovascular atherosclerosis, patients with polyvascular atherosclerosis benefit more, as the absolute risk of ischemic events is higher - with the same risk of bleeding.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 13","pages":"741-746"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144176129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Polyvascular atherosclerosis]. (Polyvascular动脉粥样硬化)。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-06-01 Epub Date: 2025-05-28 DOI: 10.1055/a-2359-4339
Christine Espinola-Klein
{"title":"[Polyvascular atherosclerosis].","authors":"Christine Espinola-Klein","doi":"10.1055/a-2359-4339","DOIUrl":"https://doi.org/10.1055/a-2359-4339","url":null,"abstract":"","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 13","pages":"723"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144176156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Bronchiectasis disease]. (支气管扩张疾病)。
Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-06-01 Epub Date: 2025-05-19 DOI: 10.1055/a-2145-7495
Judith Smith, Michael Dreher
{"title":"[Bronchiectasis disease].","authors":"Judith Smith, Michael Dreher","doi":"10.1055/a-2145-7495","DOIUrl":"10.1055/a-2145-7495","url":null,"abstract":"<p><p>Bronchiectasis is a worldwide inflammatory disease with different epidemiology and heterogenous etiology. The disease burden is high for patients and economic costs can be immense. So far there are no special disease modifying drugs available for patients with bronchiectasis other than cystic fibrosis. With rising numbers of newly diagnosed patients (prevalence 120/100000 in Germany) due to different reasons (idiopathic, postinfectious, genetic, asthma, COPD etc.) the awareness for this once called orphan disease should rise - not only among pulmonologists but also among general care practitioners. This article focuses on diagnostic algorithms and multimodal treatment options based on the latest studies and the recently published German bronchiectasis guideline from May 2024. It outlines what general care practitioners can do for their patients, what they should consider when treating an exacerbation and that special surveillance of these patients is needed in centers with expertise in this disease due to its complexity. With upcoming treatment options just as disease modifying drugs like DDP-1 inhibitors or inhaled antibiotics one can expect a change in disease treatment and outcome. Therefore, it is more and more important to raise awareness for bronchiectasis starting at the very basis when patients present at their general care practitioner with recurring productive cough, exacerbations, and further cardinal symptoms of bronchiectasis disease.</p>","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 12","pages":"703-712"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144103366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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