Deutsche medizinische Wochenschrift (1946)最新文献

[Addiction in old age]. [老年成瘾]。

IF 0.7

Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-10-01 Epub Date: 2025-09-29 DOI: 10.1055/a-2629-2014

Irmgard Vogt, Martin Schmid

引用次数: 0

[Tuberculosis - New perspectives in diagnosis and treatment]. [结核病——诊断和治疗的新视角]。

IF 0.7

Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-10-01 Epub Date: 2025-09-29 DOI: 10.1055/a-2698-9661

Pia Hartmann

引用次数: 0

[Extrapulmonary tuberculosis]. (肺外结核病)。

IF 0.7

Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-10-01 Epub Date: 2025-09-29 DOI: 10.1055/a-2597-9679

Angela Klingmüller, Jonathan Steinke, Jan Rybniker, Isabelle Suárez

引用次数: 0

[Screening and Prevention of Chronic Viral Hepatitis]. [筛选及预防慢性病毒性肝炎]。

IF 0.7

Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-10-01 Epub Date: 2025-10-10 DOI: 10.1055/a-2532-6320

Markus Cornberg, Lisa Sandmann

引用次数: 0

[34-year-old patient with hemorrhagic stomatitis, conjunctivitis and exanthema]. [34岁出血性口炎、结膜炎、湿疹患者]。

IF 0.7

Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-10-01 Epub Date: 2025-09-29 DOI: 10.1055/a-2658-0867

Fabian Görke, Henning Trawinski, Christoph Lübbert

引用次数: 0

[30-year-old patient with several spontaneously occurring lesions]. [30岁患者自发性病变]。

IF 0.7

Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-10-01 Epub Date: 2025-10-10 DOI: 10.1055/a-2653-7137

Julian P Kionke, Valentina L Müller, Alexander Kreuter

引用次数: 0

[New methods of tuberculosis diagnostics]. [结核病诊断的新方法]。

IF 0.7

Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-10-01 Epub Date: 2025-09-29 DOI: 10.1055/a-2612-2417

Alexander Mischnik, Martin Kuhns, Lennard Meiwes, Steffen Pichlo, Julia Gaudlitz, Nika Zielinski, Thomas Theo Brehm

{"title":"[New methods of tuberculosis diagnostics].","authors":"Alexander Mischnik, Martin Kuhns, Lennard Meiwes, Steffen Pichlo, Julia Gaudlitz, Nika Zielinski, Thomas Theo Brehm","doi":"10.1055/a-2612-2417","DOIUrl":"10.1055/a-2612-2417","url":null,"abstract":"Tuberculosis remains the leading cause of death by a single infectious agent worldwide, with over 10 million cases annually. Despite global efforts, delayed or missed diagnoses continue to fuel transmission and mortality, particularly in resource-limited settings. This review outlines both the current diagnostic standards - microscopy, culture, and nucleic acid amplification tests - and highlights promising innovations aimed at improving diagnosis of tuberculosis disease. Novel approaches include stool polymerase chain reaction (PCR), CRISPR (clustered regularly interspaced short palindromic repeats)-based detection of circulating cell-free DNA (cfDNA), transcriptomic signatures, molecular bacterial load assay (MBLA), lipoarabinomannan (LAM) detection in urine or sputum, and non-invasive sampling techniques using exhaled breath condensate, face masks or oral swabs. Furthermore, advancements in imaging technologies and AI (artificial intelligence)-based tools may enhance diagnostic accuracy. Together, these developments have the potential to accelerate and simplify tuberculosis diagnostics in the future.","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 20","pages":"1198-1206"},"PeriodicalIF":0.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Crisis as opportunity - The significance of crisis for moral development during medical training]. [危机即机遇——危机对医学训练中道德发展的意义]。

IF 0.7

Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-10-01 Epub Date: 2025-10-10 DOI: 10.1055/a-2668-7256

Sibylle C Mellinghoff, Eyleen Reifarth, Claudia Paganini

{"title":"[Crisis as opportunity - The significance of crisis for moral development during medical training].","authors":"Sibylle C Mellinghoff, Eyleen Reifarth, Claudia Paganini","doi":"10.1055/a-2668-7256","DOIUrl":"https://doi.org/10.1055/a-2668-7256","url":null,"abstract":"The process of becoming a medical specialist is a transformative phase with professional competence as well as personal development. This study examines the role of crisis in the moral development of physicians during their postgraduate training.Based on Carol Gilligan's ethics of care and interviews with 45 physicians in Germany, the study demonstrates that crises can be an opportunity for the reflection on ethical problems and of moral maturity.The results show that more than half of the participants experienced at least one crisis during their training that significantly impacted their emotional and professional balance. Main triggers were workload, challenging patient situations, and conflicts with supervisors. Women were more frequently affected. These crises not only led to professional changes such as job change or temporary career breaks but also influenced the physicians' self-conception and moral values. Profound ethical reflections and changes such as an increased awareness of compassion, and moral integrity were observed. Peer exchange proved to be an important resource in coping with these situations. Many respondents expressed a desire for more structural and institutional support.The study highlights the importance of ethical competencies and interpersonal care in medical training. By integrating ethics of care, physicians can grow not only professionally but also morally, thereby contributing to holistic patient care.","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 21","pages":"e50-e57"},"PeriodicalIF":0.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145276960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Interdisciplinary strategies for the prevention and treatment of MASLD]. [预防和治疗MASLD的跨学科策略]。

IF 0.7

Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-10-01 Epub Date: 2025-10-10 DOI: 10.1055/a-2532-5919

Natascha Röhlen, Katharina Laubner, Jochen Seufert, Robert Thimme

引用次数: 0

[Hepatocellular Carcinoma: from Screening to Therapy]. [肝细胞癌：从筛查到治疗]

IF 0.7

Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-10-01 Epub Date: 2025-10-10 DOI: 10.1055/a-2532-6269

Laura Hölzen, Jens Marquardt, Carolin Zimpel

{"title":"[Hepatocellular Carcinoma: from Screening to Therapy].","authors":"Laura Hölzen, Jens Marquardt, Carolin Zimpel","doi":"10.1055/a-2532-6269","DOIUrl":"https://doi.org/10.1055/a-2532-6269","url":null,"abstract":"Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and a leading cause of cancer-related death worldwide. The incidence is increasing globally, primarily due to the rising prevalence of chronic liver diseases. While chronic viral hepatitis (HBV, HCV) and alcohol abuse have traditionally been considered the main risk factors, metabolic dysfunction-associated steatohepatitis (MASH) is increasingly gaining importance, especially in Western industrialized nations. In the vast majority of cases, HCC develops on the basis of liver cirrhosis. When cirrhosis is present, diagnosis can usually be reliably made through dynamic imaging techniques. However, despite established surveillance programs, most cases of HCC are often diagnosed only at advanced stages, which significantly limits therapeutic options. The treatment of HCC depends on tumor stage, overall health, and liver function of the affected patients. Selecting the appropriate therapy requires a multidisciplinary decision-making process. While curative options include resection, transplantation, and local ablation, advanced stages are managed with loco-regional therapies or systemic treatments. In recent years, the therapeutic spectrum has been significantly expanded by the introduction of immune checkpoint inhibitors. Particularly, immunotherapeutic combination therapies approved for first-line treatment have significantly improved the overall survival of patients with advanced HCC. Nevertheless, the prognosis remains unfavorable in many cases, highlighting the need for further research to identify predictive biomarkers and develop innovative therapies.","PeriodicalId":93975,"journal":{"name":"Deutsche medizinische Wochenschrift (1946)","volume":"150 21","pages":"1276-1282"},"PeriodicalIF":0.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145276964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0