[Antithrombotic therapy for polyvascular atherosclerosis].

Deutsche medizinische Wochenschrift (1946) Pub Date : 2025-06-01 Epub Date: 2025-05-28 DOI:10.1055/a-2359-4422
Christine Espinola-Klein
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Abstract

Patients with polyvascular atherosclerosis are twice as likely to have cardiovascular events as patients with monovascular atherosclerosis. Anticoagulant therapy improves the prognosis and is therefore clearly recommended. Intensified anticoagulation is more effective in reducing risk but is associated with a higher risk of bleeding. Compared to patients with monovascular atherosclerosis, patients with polyvascular atherosclerosis benefit more, as the absolute risk of ischemic events is higher - with the same risk of bleeding.

[多血管粥样硬化的抗血栓治疗]。
多血管动脉粥样硬化患者发生心血管事件的可能性是单血管动脉粥样硬化患者的两倍。抗凝治疗可改善预后,因此明确推荐使用。强化抗凝在降低风险方面更有效,但与出血风险较高相关。与单血管动脉粥样硬化患者相比,多血管动脉粥样硬化患者受益更多,因为缺血性事件的绝对风险更高-出血风险相同。
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