Current health sciences journal最新文献_第3页

Assessment of Neutrophil-Lymphocyte Ratio and Systemic Immune-Inflammation Index in Systemic Scleroderma Patients with Focus on Cardiopulmonary Manifestations. 评估系统性硬皮病患者的中性粒细胞-淋巴细胞比率和系统免疫-炎症指数，重点关注心肺表现。

Current health sciences journal Pub Date : 2024-07-01 Epub Date: 2024-09-30 DOI: 10.12865/CHSJ.50.03.09

Camelia Palici, Stefan Cristian Dinescu, Cristina Elena Bita, Alesandra Florescu, Anca Emanuela Musetescu, Florentin Vreju, Paulina Lucia Ciurea

{"title":"Assessment of Neutrophil-Lymphocyte Ratio and Systemic Immune-Inflammation Index in Systemic Scleroderma Patients with Focus on Cardiopulmonary Manifestations.","authors":"Camelia Palici, Stefan Cristian Dinescu, Cristina Elena Bita, Alesandra Florescu, Anca Emanuela Musetescu, Florentin Vreju, Paulina Lucia Ciurea","doi":"10.12865/CHSJ.50.03.09","DOIUrl":"10.12865/CHSJ.50.03.09","url":null,"abstract":"Objectives: To quantify levels of two inflammation-related indexes, namely neutrophil-lymphocyte ratio (NLR) and systemic immune-inflammation index (SII) in systemic scleroderma patients and determine the association with clinical manifestations and features of heart ultrasound.Methods: The study group consisted of 34 patients with diagnosis of systemic scleroderma which were admitted to the hospital during 2015-2019. Patient data included the presence and type of clinical manifestations of systemic scleroderma, chest imaging to screen for lung disease, heart ultrasound reports and the laboratory investigations needed to quantify inflammatory indexes. We analysed the levels of inflammatory indexes and compared results based on the prevalence of systemic manifestations.Results: Higher serum levels of NLR and SII are associated with the presence of joint, lung and pericardial involvement. Statistical significance was observed only for NLR levels with regard to the presence of articular involvement and ILD. Low ejection fraction was also associated with higher levels of both inflammatory indexes, without statistical significance.Conclusion: Inflammatory indexes are cost-effective markers that reflect active disease manifestations of systemic scleroderma and can thus be a useful tool to include in the regular follow-up of patients in order to better inform organ-specific assessments.","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"50 5","pages":"421-427"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11578356/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142690144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anterior Pituitary Hormones are Important in Growth, but does their Deficiency Cause Skeletal Deformity? A Case Report. 垂体前叶激素对生长很重要，但缺乏垂体前叶激素会导致骨骼畸形吗？病例报告。

Current health sciences journal Pub Date : 2024-07-01 Epub Date: 2024-09-30 DOI: 10.12865/CHSJ.50.03.13

Yasemin Yumusakhuylu, Afitap Içağasioğlu, Ayla Guven

引用次数: 0

Non-Alpine Thyroid Angiosarcoma Presenting with Unique Spinal Metastasis: A Rare Case Report from Pakistan. 出现独特脊柱转移的非阿尔卑斯甲状腺血管肉瘤：来自巴基斯坦的罕见病例报告

Current health sciences journal Pub Date : 2024-07-01 Epub Date: 2024-09-30 DOI: 10.12865/CHSJ.50.03.15

Seyreen Faisal, Hadia Wali, Tahir Muhammad, Tafiya Erum Kamran, Rabia Saleem

引用次数: 0

The Relationship between Sleep Bruxism Index and Quality of Life. 睡眠磨牙指数与生活质量之间的关系

Current health sciences journal Pub Date : 2024-07-01 Epub Date: 2024-09-30 DOI: 10.12865/CHSJ.50.03.10

Elena Claudia Sin, Gheorghe Raftu, Steliana Gabriela Buștiuc, Aurelian Caraiane, Raluca Briceag

{"title":"The Relationship between Sleep Bruxism Index and Quality of Life.","authors":"Elena Claudia Sin, Gheorghe Raftu, Steliana Gabriela Buștiuc, Aurelian Caraiane, Raluca Briceag","doi":"10.12865/CHSJ.50.03.10","DOIUrl":"10.12865/CHSJ.50.03.10","url":null,"abstract":"Aim of the study: The aim of this study was represented by the identification of the type of relation between the bruxism sleep index and the global quality of life.Materials and methods: The study group was composed of a number of 40 patients, both women and men, who did not report health problems and who were identified with a positive self-report regarding the existence of sleep bruxism. For the identification of the bruxism index, the Bruxoff device, Bioelettronica, Turin, Italy, was used. Quality of life inventory (QOLI) was used to determine quality of life scores (T-score).Results: The gender distribution of the batch is as follows: 52.5%-male, 47.5%-female. The maximum value of the bruxism index was 10.5, and the minimum was 2.10, with a mean of 6.30 and a standard deviation of 2.22. Quality of life T-score recorded maximum value equal to 62, minimum value equal to 40, mean equal to 51.87. The Pearson correlation coefficient calculated to test the correlation between the bruxism indicator and the QOLI T Score presented a negative value (-0.643), which signifies a negative but very strong relation between the two variables. 77.5% of the participants were included in a mean level of quality of life.Conclusions: A statistically strong negative relation was found between global quality-of-life (T-scores) and the bruxism indicator in patients with bruxism activity during sleep.","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"50 5","pages":"428-435"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11578362/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142690005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is Serum Matrix Metalloproteinase 9 and/or D-Dimer Levels a Marker for Identifying Abdominal Aortic Aneurysms in Patients with Significant Coronary Atherosclerosis? 血清基质金属蛋白酶 9 和/或 D-二聚体水平是识别冠状动脉粥样硬化患者腹主动脉瘤的标志物吗？

Current health sciences journal Pub Date : 2024-07-01 Epub Date: 2024-09-30 DOI: 10.12865/CHSJ.50.03.07

Diduta Alina Brie, Adelina Maria Jianu, Roxana Popescu, Daniel Miron Brie, Madalina Boruga

{"title":"Is Serum Matrix Metalloproteinase 9 and/or D-Dimer Levels a Marker for Identifying Abdominal Aortic Aneurysms in Patients with Significant Coronary Atherosclerosis?","authors":"Diduta Alina Brie, Adelina Maria Jianu, Roxana Popescu, Daniel Miron Brie, Madalina Boruga","doi":"10.12865/CHSJ.50.03.07","DOIUrl":"10.12865/CHSJ.50.03.07","url":null,"abstract":"Our research aims to find a connection between the levels of MMP-9 and D-dimers in the blood and the prevalence of AAAs in subjects with atherosclerotic coronary disease. We selected fifty patients from each group and measured their MMP-9 and D-dimer levels in the blood. We discovered that in subjects with significant coronary disease and angina pectoris, the level of MMP-9 is higher compared to the subjects with angina pectoris but without significant coronary disease. When comparing this group with those with significant coronary disease and AAA, the level of MMP-9 is lower. Additionally, the D-dimer level was significantly higher in subjects with both AAA and significant coronary atherosclerosis compared to patients with significant coronary disease alone or those without significant coronary disease or AAAs. Subjects with significant coronary disease and AAA have elevated levels of MMP-9 and D-dimer compared to patients with significant coronary disease alone or without coronary artery disease or AAAs. These two factors could be used as indicators for diagnosing AAA in patients with angina pectoris.","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"50 5","pages":"405-410"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11578357/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142688775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of Surgical and Non-surgical Outcomes in Patients with Dementia and Hip Fractures. 评估痴呆症和髋部骨折患者的手术和非手术治疗效果。

Current health sciences journal Pub Date : 2024-07-01 Epub Date: 2024-09-30 DOI: 10.12865/CHSJ.50.03.05

Andrei Vlad Bradeanu, Iulian Bounegru, Loredana Sabina Pascu, Anamaria Ciubara, Tudor Adrian Balseanu

{"title":"Assessment of Surgical and Non-surgical Outcomes in Patients with Dementia and Hip Fractures.","authors":"Andrei Vlad Bradeanu, Iulian Bounegru, Loredana Sabina Pascu, Anamaria Ciubara, Tudor Adrian Balseanu","doi":"10.12865/CHSJ.50.03.05","DOIUrl":"10.12865/CHSJ.50.03.05","url":null,"abstract":"Introduction: The aging population is associated with increased osteoporosis and risk of hip fractures. Cognitive decline has recorded exponential increases in the last decades, with the rise in life expectancy.Material and methods: We conducted a prospective study on 65 patients over 65 years old associated with dementia and hip fractures. We used pre-and post-treatment variables such as age, type of fracture, type of treatment, Charlson Comorbidity Index (CCI), EQ-5D-5L score, and the Harris hip score (HHS) to assess pain, mobility, and mortality. We performed follow-ups at 6 months, 1 year, 2 years, and 3 years.Results: Patients with dementia typically arrive at the hospital without any previous analgesic treatment and receive lower doses due to poor pain recognition. The 6-month mortality rate was 48.22% and increased to 78.46% at 3 years. The best survival rates were in patients with bipolar prosthesis and Gamma nails, with a 3-year survival rate of 40% and 50%, respectively.Conclusions: Patients with dementia have a higher mortality rate compared to cognitively intact patients and the treatment decisions require a multidisciplinary team and individualized recommendations for each patient, due to high surgical risk in the elderly.","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"50 5","pages":"381-391"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11578367/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142690146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment and Rehabilitation in Sarcopenic Patients. 肌肉松弛症患者的评估和康复。

Current health sciences journal Pub Date : 2024-07-01 Epub Date: 2024-09-30 DOI: 10.12865/CHSJ.50.03.04

Bianca-Maria Vlăduțu, Mircea-Sebastian Șerbănescu, Magdalena Rodica Trăistaru

{"title":"Assessment and Rehabilitation in Sarcopenic Patients.","authors":"Bianca-Maria Vlăduțu, Mircea-Sebastian Șerbănescu, Magdalena Rodica Trăistaru","doi":"10.12865/CHSJ.50.03.04","DOIUrl":"10.12865/CHSJ.50.03.04","url":null,"abstract":"Sarcopenia is a degenerative disorder that particularly affects older people and is defined by a pathological decrease in muscle strength. This disease represents one of the topics of great interest in the medical world of the last two decades. In our study, we tried to underline the importance of an adapted recovery program based on physical exercise for regaining clinical and functional status in patients with age-related sarcopenia. No nutritional intervention was applied. We performed our rehabilitation program in accordance with present international recommendations for sarcopenia. After complete assessment, our patients were randomised into two groups: G1 (Lot 1=25 patients) and G2 (Lot 2=15 patients). G1 patients were compliant with kinetic training, and performed all rehabilitation measures, and G2 patients accepted rehabilitation program without kinetic exercises. Patients assessment (lab tests, gait analysis, VAS and the Clinical Frailty Scale) was made on two levels-first (T1-inpatient assessment), and after 6 months (T2-outpatient assessment). The rehabilitation program based on the kinetic program brought positive improvements in physical performance and locomotion (gait speed and walking cadence) in sarcopenic patients.","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"50 3","pages":"368-380"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11578358/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142690115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Testing a Psychological Intervention in Elite Athletes to Alleviate the Psychomotor Consequences of Doping: The Moderating Role of Personality. 测试对精英运动员进行心理干预以减轻兴奋剂造成的心理运动后果：人格的调节作用。

Current health sciences journal Pub Date : 2024-07-01 Epub Date: 2024-09-30 DOI: 10.12865/CHSJ.50.03.06

Eugen Coli, Leon Zgrean, Monica Grigore, Aurel Popa-Wagner

{"title":"Testing a Psychological Intervention in Elite Athletes to Alleviate the Psychomotor Consequences of Doping: The Moderating Role of Personality.","authors":"Eugen Coli, Leon Zgrean, Monica Grigore, Aurel Popa-Wagner","doi":"10.12865/CHSJ.50.03.06","DOIUrl":"10.12865/CHSJ.50.03.06","url":null,"abstract":"This study aimed to evaluate a psychological intervention intended to reduce the psychomotor effects of doping. The research also examined how conscientiousness and emotional stability moderated the intervention's effectiveness. The intervention was developed based on the literature and included two components: biofeedback and mental imagery/rehearsal. Athletes reported higher scores post-intervention in coordination, sports skills, overall physical condition, strength, flexibility, endurance, and general self-esteem. Similar results have been observed in previous studies related to biofeedback and mental imagery. According to the results, athletes with higher conscientiousness benefited more from the intervention in terms of coordination, flexibility, and endurance. The data support the idea that emotionally stable athletes benefit more from the intervention in terms of overall physical condition and general self-esteem. Theoretically, the studies highlight the importance of psychological interventions in enhancing athletes' psychomotor performance and the interaction between these interventions and individual differences among participants. The findings are relevant for sports psychology practitioners, as they provide additional evidence for the use of biofeedback and mental imagery with athletes.","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"50 5","pages":"392-404"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11578365/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142690001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Limb Salvage Surgery in Pediatric Patients with Osteosarcoma. 骨肉瘤小儿患者的肢体救治手术

Current health sciences journal Pub Date : 2024-07-01 Epub Date: 2024-09-30 DOI: 10.12865/CHSJ.50.03.03

Ștefan Adrian Niculescu, Alexandru Florian Grecu, Cristian Gheonea, Dan Cristian Grecu

{"title":"Limb Salvage Surgery in Pediatric Patients with Osteosarcoma.","authors":"Ștefan Adrian Niculescu, Alexandru Florian Grecu, Cristian Gheonea, Dan Cristian Grecu","doi":"10.12865/CHSJ.50.03.03","DOIUrl":"10.12865/CHSJ.50.03.03","url":null,"abstract":"Osteosarcoma, although rare, is acknowledged as the most common primary bone tumor in children and adolescents. Osteosarcoma is a highly malignant osteogenic tumor that can develop in any bone, but commonly develops at the metaphysis of long bones. The positive diagnosis of osteosarcoma is based on the pathology exam, since there are no other specific diagnostic tools, and the patients with osteosarcoma are typically treated by a multidisciplinary team of specialists. The mainstream for the surgical treatment of limb osteosarcoma is the limb salvage surgery, whenever this approach does not compromise the oncological outcomes. A large spectrum of reconstructive surgical procedures is used in various centers, and to date there is no large consensus on recommending one over another. It is often that the practitioner has to decide whether the final impact on the quality of life of the child undergoing endoprosthetic replacement or osteoarticular allograft is better with the subsequent inequality of the length of the limb or the radical approach by amputation is better. Special consideration has to be given on the aspects of psychosocial wellbeing of the patients following the initial surgical intervention.","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"50 3","pages":"360-367"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11580753/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142690122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cutaneous Metastases of Signet-Ring Cell Gastric Carcinoma: A Case Report. 西格奈细胞胃癌的皮肤转移：病例报告。

Current health sciences journal Pub Date : 2024-07-01 Epub Date: 2024-09-30 DOI: 10.12865/CHSJ.50.03.12

Gökçe Isil Kurmus, Filiz Canpolat, Müzeyyen Gönül, Aysun Gökçe, Selda Pelin Kartal

{"title":"Cutaneous Metastases of Signet-Ring Cell Gastric Carcinoma: A Case Report.","authors":"Gökçe Isil Kurmus, Filiz Canpolat, Müzeyyen Gönül, Aysun Gökçe, Selda Pelin Kartal","doi":"10.12865/CHSJ.50.03.12","DOIUrl":"10.12865/CHSJ.50.03.12","url":null,"abstract":"The cutaneous metastases from carcinoma of the stomach are rare and either an index of a silent visceral neoplasm or a recurrence of an already diagnosed malignancy. They usually present as asymptomatic nodules or plaques; thus, they can be mistaken for other skin conditions, which leads to a potential misdiagnosis. The definition of signet-ring cell (SRC) gastric carcinoma is that it can easily cause a diffusion enbloc through lymphatic and hematogenous pathways, inducing skin manifestations such as indurated plaques, nodules, and erysipelas-like lesions. The infrequency of skin metastasis from gastric carcinoma underlines once more the need for increased awareness on the part of clinicians. Diagnosis, histopathological examination, and immunohistochemistry are essential. The confirmation of SRC tumors is done by staining for mucin, such as periodic acid-Schiff (PAS) and mucicarmine, and by using immunohistochemical markers like CK7. Almost always, cutaneous metastasis from SRC gastric carcinoma has a poor prognosis since these tumors are highly aggressive and chemotherapy-resistant. We present a case of cutaneous metastasis from SRC gastric carcinoma, a subtype of gastric cancer with a well-documented tendency both for distant and cutaneous spread. Generally, skin metastases from SRC gastric carcinoma are associated with poor prognosis, rapid progression of the disease, and a high mortality rate. This case underlines the need for early detection and a multidisciplinary approach by dermatologists, oncologists, and surgeons to improve outcomes in such patients.","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"50 5","pages":"444-447"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11578364/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142690149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0