Current health sciences journal最新文献_第3页

Metabolic and Inflammatory Disorders-Main Influencers of Psoriatic Arthritis Activity. 代谢和炎症紊乱——银屑病关节炎活动的主要影响因素。

Current health sciences journal Pub Date : 2026-01-01 Epub Date: 2026-03-31 DOI: 10.12865/CHSJ.52.01.06

Larisa Ionela Suiu, Paulina Lucia Ciurea, Cristina Elena Bita, Francesco Porta, Florentin Ananu Vreju

{"title":"Metabolic and Inflammatory Disorders-Main Influencers of Psoriatic Arthritis Activity.","authors":"Larisa Ionela Suiu, Paulina Lucia Ciurea, Cristina Elena Bita, Francesco Porta, Florentin Ananu Vreju","doi":"10.12865/CHSJ.52.01.06","DOIUrl":"10.12865/CHSJ.52.01.06","url":null,"abstract":"Background: Psoriatic arthritis is a systemic, potentially severe condition associated with multiple comorbidities. It is characterized by peripheral and axial joint involvement, enthesitis, and association with various comorbidities.Objective: This study aims to identify some of the determinants of the severity of psoriatic arthritis. We studied the prevalence and common pathogenic mechanisms of various comorbidities associated with PsA.Methods: We studied 103 patients diagnosed with psoriatic arthritis. 69 met the inclusion criteria. We evaluated the disease activity index DAPSA, ESH, CRP, BMI, uric acid, cholesterol, triglycerides. Disease duration and type of joint involvement were also included.Results: The patients in the studied group had an average age of 54.75 (sd±10.02) years and there were 36 (55.38%) women. Duration of the diseases 8.254 (sd±5.307) years and an average of DAPSA values of 20.58 (sd±8.522).Clinical manifestations: 37 (56.92%) had peripheral damage; 6 (9.23%) had axial damage and 22 (33.85%) had mixed axial and peripheral damage. Inflammatory markers: ESR with an average serum value of 39.55 (sd±26.43) mm/h and average CRP values of 17.69mg/L (sd±28.71). The body mass index-an average value of 29.69Kg/m² (sd±5.979). Biological markers: uric acid with an average serum value of 9.832 mg/dl (sd±2.089), triglycerides 262.6 mg/dl (sd±41.58) and cholesterol 319.8mg/dl (sd±56.14).Conclusions: Serum levels of uric acid, cholesterol, triglycerides, ESR, and CRP influence psoriatic arthritis activity and response to treatment.","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"52 1","pages":"48-54"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13198760/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148019522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk of Eating Disorders between Exercisers and Non-Exercisers among Nursing Personnel: A Cross-Sectional Analytical Study. 护理人员中锻炼者与非锻炼者饮食失调风险的横断面分析研究

Current health sciences journal Pub Date : 2026-01-01 Epub Date: 2026-03-31 DOI: 10.12865/CHSJ.52.01.03

Agila Yoganandame, Vembu Krishnasamy

{"title":"Risk of Eating Disorders between Exercisers and Non-Exercisers among Nursing Personnel: A Cross-Sectional Analytical Study.","authors":"Agila Yoganandame, Vembu Krishnasamy","doi":"10.12865/CHSJ.52.01.03","DOIUrl":"10.12865/CHSJ.52.01.03","url":null,"abstract":"Background: Eating disorders are mental health conditions characterized by unhealthy eating behaviors that adversely affect physical and emotional well-being. This study assessed the risk of eating disorders among nursing personnel, comparing exercisers and non-exercisers, and explored associations between selected factors and eating disorder risk in both groups.Methodology: A cross-sectional analytical study was conducted among nursing personnel. The risk of eating disorders was assessed using the SCOFF Questionnaire. A total of 422 participants who met the inclusion criteria and consented to participate were included. Statistical analysis was performed using STATA version 14. Descriptive statistics were used to summarize the data, and the Chi-square test was used to assess associations, with statistical significance set at p<0.05.Results: A total of 422 participants were included, with a mean age of 32.98±6.38 years. Among non-exercisers, 33.22% were at risk of eating disorders compared with 24.79% among exercisers. Overall, 30.81% of participants were at risk, while 69.19% had no risk. A significant association was observed between BMI and eating disorder risk among non-exercisers (p<0.001), with a higher proportion of risk among participants with BMI≥25.Conclusion: The findings suggest that eating disorder risk was associated with higher BMI and marital status among non-exercisers. Regular screening, promotion of physical activity, and education on healthy dietary practices may help improve the well-being of nursing personnel.","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"52 1","pages":"21-29"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13198752/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148019647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Silent Giant: A Case of Giant Submandibular Sialolithiasis with Minimal Symptoms. 沉默的巨人：一例症状轻微的巨大下颌下涎石症。

Current health sciences journal Pub Date : 2026-01-01 Epub Date: 2026-03-31 DOI: 10.12865/CHSJ.52.01.15

Giulia Francesca Maltese, Francesco Luppi, Michele Domenico Spampinato, Roberto DE Giorgio, Matteo Guarino

{"title":"The Silent Giant: A Case of Giant Submandibular Sialolithiasis with Minimal Symptoms.","authors":"Giulia Francesca Maltese, Francesco Luppi, Michele Domenico Spampinato, Roberto DE Giorgio, Matteo Guarino","doi":"10.12865/CHSJ.52.01.15","DOIUrl":"10.12865/CHSJ.52.01.15","url":null,"abstract":"Background: Sialolithiasis is a common condition affecting the salivary glands, typically presenting with pain and swelling, typically during meals. giant sialoliths (>15mm) are rare and usually symptomatic, often requiring surgical intervention.Case presentation: We report the case of a patient who remained completely asymptomatic despite harbouring a 35 x 20mm ovoidal sialolith in the submandibular gland. the patient presented to the emergency department with sudden onset of submandibular pain during the night prior to admission. Clinical examination and imaging confirmed the presence of a large, well-defined, spherical calculus. Remarkably, the stone was manually removed by an otolaryngologist without the need of surgical intervention or anaesthesia.Discussion: This case is notable for the unusually large size and spherical shape of the sialolith, the absence of prior symptoms, and the successful non-surgical removal. such presentations are extremely rare and highlight the importance of considering sialolithiasis even in atypical clinical scenarios.Conclusion: This case contributes to the limited literature on asymptomatic giant sialoliths and supports the feasibility of non-invasive management in select cases.","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"52 1","pages":"128-131"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13198754/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148019657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prognostic Value of Spontaneous Activity on Laryngeal Electromyography for Recovery of Vocal Fold Motion: A Systematic Review of Observational Studies. 喉肌电图自发活动对声带运动恢复的预后价值：观察性研究的系统回顾。

Current health sciences journal Pub Date : 2026-01-01 Epub Date: 2026-03-31 DOI: 10.12865/CHSJ.52.01.02

Shirley Tarabichi, Carmen Aurelia Mogoanta, Codrut Sarafoleanu

{"title":"Prognostic Value of Spontaneous Activity on Laryngeal Electromyography for Recovery of Vocal Fold Motion: A Systematic Review of Observational Studies.","authors":"Shirley Tarabichi, Carmen Aurelia Mogoanta, Codrut Sarafoleanu","doi":"10.12865/CHSJ.52.01.02","DOIUrl":"10.12865/CHSJ.52.01.02","url":null,"abstract":"Background-Vocal fold motion impairment resulting from laryngeal nerve injury poses a recurring prognostic dilemma in clinical practice. While laryngeal electromyography (LEMG) has been increasingly adopted as an objective tool for neuromuscular assessment, the specific prognostic value of spontaneous activity for predicting recovery of vocal fold motion remains incompletely defined. This systematic review aimed to evaluate the relationship between the presence of spontaneous activity on LEMG and subsequent vocal fold motion recovery across observational studies. Methods-A systematic search of MEDLINE (via PubMed), Embase, Scopus and the Cochrane Library databases was conducted in accordance with PRISMA guidelines, covering publications up to March 2026. Results-Across the included studies, the presence of spontaneous activity on LEMG-particularly fibrillation potentials-was consistently associated with poor recovery of vocal fold motion. Patients demonstrating active denervation potentials showed significantly lower rates of meaningful functional recovery compared to those in whom spontaneous activity was absent. This association held across multiple etiological subgroups, including post-surgical and idiopathic cases, though the strength of the relationship varied with the timing of LEMG relative to injury onset and the duration of follow-up. Conclusions-Spontaneous activity on LEMG represents a clinically meaningful predictor of unfavorable prognosis for vocal fold motion recovery. Standardization of LEMG protocols and reporting criteria across future studies remains essential to strengthen the evidence base in this field.","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"52 1","pages":"7-20"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13198761/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148019649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring Potential Correlations Between Oxidative Stress Markers and Inflammatory Pivotal Factors in Children with Hematological Malignancies. 探讨儿童血液恶性肿瘤中氧化应激标志物和炎症关键因子的潜在相关性。

Current health sciences journal Pub Date : 2026-01-01 Epub Date: 2026-03-31 DOI: 10.12865/CHSJ.52.01.07

Cezar Ilie Foia, Eric Oliviu Cosovanu, Larisa Ghemiș, Andra Melissa Tarțău, Daniel Cioloca, Alin Dumitru Ciubotaru, Alina Elena Adumitroaie

{"title":"Exploring Potential Correlations Between Oxidative Stress Markers and Inflammatory Pivotal Factors in Children with Hematological Malignancies.","authors":"Cezar Ilie Foia, Eric Oliviu Cosovanu, Larisa Ghemiș, Andra Melissa Tarțău, Daniel Cioloca, Alin Dumitru Ciubotaru, Alina Elena Adumitroaie","doi":"10.12865/CHSJ.52.01.07","DOIUrl":"10.12865/CHSJ.52.01.07","url":null,"abstract":"Background: Hematological malignancies are associated to immune status alterations and an amplified systemic and local immune response, which can have a significant impact on oral health, especially concerning gingival and periodontal status. Along with cytokines, which play an important role in regulating local and systemic inflammation, oxidative stress factors also reflect a critical involvement in the evolution of periodontal alterations, especially in association to systemic conditions such as leukemia. This study aims to investigate certain inflammatory markers (such as IL-1β, IL-6, IL-17α and TGF-β) as well as oxidative stress factors (SOD, MDA, 8-OHdG), in order to identify any correlations between the two, in a comparative manner, in children with leukemia and individuals without this malignant disease.Methodology: The study evaluated inflammatory markers and oxidative stress factors both in plasma and gingival crevicular fluid of 97 children (47 in the study group, suffering from leukemia and 50 in the control group, without the oncological condition or any other inflammatory systemic disease).Results: In plasma, MDA seems to be the most powerful association, rising along with increased plasmatic values of IL-1β, IL-17α and TGF-β. In GCF, SOD and 8-OHdG associate with inflammatory indicators, suggesting a complex synergy between cytokine expression and oxidative stress mechanisms.Conclusions: Our analysis showed significant associations between the evaluated inflammatory markers and oxidative stress factors, both in plasma and gingival crevicular fluid. These observations might underline a potential role of certain biomarkers to act out as indicators of a complex interconnection between inflammatory status and oxidative stress.","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"52 1","pages":"55-64"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13198753/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148019302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CD133 Immunoexpression in Prostatic Acinar Adenocarcinomas. CD133在前列腺腺泡癌中的免疫表达。

Current health sciences journal Pub Date : 2026-01-01 Epub Date: 2026-03-31 DOI: 10.12865/CHSJ.52.01.09

Adrian Mihai Stoiculescu, Oana-Iulia Crețu, Bianca Cătălina Andreiana, Alex Emilian Stepan

{"title":"CD133 Immunoexpression in Prostatic Acinar Adenocarcinomas.","authors":"Adrian Mihai Stoiculescu, Oana-Iulia Crețu, Bianca Cătălina Andreiana, Alex Emilian Stepan","doi":"10.12865/CHSJ.52.01.09","DOIUrl":"10.12865/CHSJ.52.01.09","url":null,"abstract":"Prostatic acinar adenocarcinomas (PAA) continue to represent a challenge in terms of incidence and efficiency of screening and targeted therapy programs. The capacity of the tumor cell population to renew itself through differentiation and activation of stem cells constitutes a mechanism of tumor protection and survival, but also of acquisition of aggressive phenotypes. In this study, we analyzed CD133 immunoexpression in 55 cases, in relation to the clinico-epidemiological and histopathological parameters of the tumors. CD133 reactions were present at the nuclear and cytoplasmic level and focally membranous in tumor and stromal cells, both from tumor areas and in the case of non-neoplastic tissue. CD133 showed significantly higher reactions in PAA diagnosed in patients in extreme age groups and with elevated serum PSA values. Immunoreactions were significantly higher in some subtypes of PAA (conventional and colloid), in advanced grading groups and with perineural and lymphovascular invasion. In addition to identifying reservoirs of cells with stem potential, CD133 can be used to identify PAA with aggressive behavior, suggesting a biological connection of the two features and the utility for stratifying patients for therapy.","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"52 1","pages":"78-85"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13198763/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148018991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cognitive Fusion-Guided Transperineal Biopsy Leading to the Diagnosis of Early Prostate Adenocarcinoma After Repeated Negative Evaluations: A Case Report. 认知融合引导下经会阴活检在反复阴性评价后导致早期前列腺癌的诊断：1例报告。

Current health sciences journal Pub Date : 2026-01-01 Epub Date: 2026-03-31 DOI: 10.12865/CHSJ.52.01.16

Mihai-Alexandru Radu, Andrei Pănuș, Andrei Drocaș, Dragoș Florin Vasile, Nicoleta Alice Drăgoescu, George Mitroi, Cecil Sorin Mirea, Petru Octavian Drăgoescu

{"title":"Cognitive Fusion-Guided Transperineal Biopsy Leading to the Diagnosis of Early Prostate Adenocarcinoma After Repeated Negative Evaluations: A Case Report.","authors":"Mihai-Alexandru Radu, Andrei Pănuș, Andrei Drocaș, Dragoș Florin Vasile, Nicoleta Alice Drăgoescu, George Mitroi, Cecil Sorin Mirea, Petru Octavian Drăgoescu","doi":"10.12865/CHSJ.52.01.16","DOIUrl":"10.12865/CHSJ.52.01.16","url":null,"abstract":"Background: Prostate cancer remains one of the most frequently diagnosed malignancies in men, where early detection is key to curative treatment. Conventional biopsy techniques can miss small or focal lesions, especially in cases with persistently elevated prostate-specific antigen (PSA) levels and uncertain imaging, risking delayed diagnosis.Case report: We present the case of a 69-year-old male who initially presented in 2022 with lower urinary tract symptoms and an elevated PSA level of 26.17ng/ml. He was diagnosed with acute prostatitis and responded favourably to targeted treatment. Over the following two years, his PSA levels remained in the \"gray zone\" (7.24-8.68ng/ml), raising continued clinical suspicion despite normal findings on digital rectal examination (DRE), PIRADS 3 lesions on serial multiparametric magnetic resonance imaging (mpMRI), and two previous transperineal prostate biopsies, including a saturation biopsy-both with benign histopathology. In July 2025, the patient presented for the first time to our center. A new mpMRI again showed a PIRADS 3 lesion in the transitional zone of the right prostatic lobe. Given the persistent suspicion and previous negative results, a transperineal cognitive fusion-guided biopsy was performed, combining MRI-targeted and systematic sampling. Histopathological evaluation identified a 0.55 mm focus of acinar adenocarcinoma with a Gleason score of 7 (3+4).Conclusion: This case illustrates how cognitive fusion-guided biopsy can detect clinically significant prostate cancer in patients who have undergone prior negative standard biopsies. The technique improves diagnostic detection rates and represents a valuable, accessible alternative for centers without computer-assisted fusion platforms.","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"52 1","pages":"132-135"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13198755/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148019343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hemothorax in Dialysis Patients: The Importance of History and Differential Diagnoses. 透析患者血胸：病史和鉴别诊断的重要性。

Current health sciences journal Pub Date : 2026-01-01 Epub Date: 2026-03-31 DOI: 10.12865/CHSJ.52.01.13

Marina Cabrio, Maria Clara Ribeiro Silva, Murilo Vidotto Leite, Andrea Antunes Cetlin

引用次数: 0

Spontaneous Closure of High-Output Duodenal Enteroatmospheric Fistula with Fistuloclysis: Case Report. 自行关闭高输出量十二指肠肠大气瘘管造瘘术1例。

Current health sciences journal Pub Date : 2026-01-01 Epub Date: 2026-03-31 DOI: 10.12865/CHSJ.52.01.14

Saulo Bueno DE Azeredo, Francesca Dal Sochio Gobbato, Marcelo DA Mota Iglesias, Giovanna Dal Sochio Gobbato, Eduarda Vogel Wollmeister, Maria Fernanda Guadagnin

{"title":"Spontaneous Closure of High-Output Duodenal Enteroatmospheric Fistula with Fistuloclysis: Case Report.","authors":"Saulo Bueno DE Azeredo, Francesca Dal Sochio Gobbato, Marcelo DA Mota Iglesias, Giovanna Dal Sochio Gobbato, Eduarda Vogel Wollmeister, Maria Fernanda Guadagnin","doi":"10.12865/CHSJ.52.01.14","DOIUrl":"10.12865/CHSJ.52.01.14","url":null,"abstract":"High-output duodenal enteroatmospheric fistulas (EAFs) are a formidable surgical challenge associated with high morbidity and mortality. Fistuloclysis, the reinfusion of proximal intestinal effluent into the distal bowel, is a management strategy aimed at preserving gut function and mitigating catabolism. We report the successful management of a 71-year-old male who developed a high-output (1,300 mL/day) duodenal EAF following a distal partial gastrectomy with Roux-en-Y reconstruction. Fistuloclysis was initiated on postoperative day seven via a feeding jejunostomy. Over a 14-day treatment period, the patient's nutritional status markedly improved, and fistula output progressively decreased to 25 mL/day. This effective effluent control resulted in the spontaneous functional closure of the tract, obviating the need for immediate surgical intervention. The patient was discharged with a granulating tract and remained recurrence-free at outpatient follow-up. This case highlights fistuloclysis as a safe and effective alternative to parenteral nutrition in managing complex duodenal EAFs. The technique was critical in reversing the patient's catabolic state, controlling fistula output, and facilitating spontaneous closure. We advocate for its early consideration in the multidisciplinary management of these challenging fistulas.","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"52 1","pages":"122-127"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13198751/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148019605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of AI Assistance on Radiologist Accuracy for Lung Nodule Detection on Chest CT. 人工智能辅助对胸部CT诊断肺结节准确性的影响

Current health sciences journal Pub Date : 2026-01-01 Epub Date: 2026-03-31 DOI: 10.12865/CHSJ.52.01.04

Cristina Mihaela Ciofiac, Mihai Alexandru Ene, Mihai Lucian Florescu, Rossy Vlăduț Teică, Ioana Andreea Gheonea

{"title":"Impact of AI Assistance on Radiologist Accuracy for Lung Nodule Detection on Chest CT.","authors":"Cristina Mihaela Ciofiac, Mihai Alexandru Ene, Mihai Lucian Florescu, Rossy Vlăduț Teică, Ioana Andreea Gheonea","doi":"10.12865/CHSJ.52.01.04","DOIUrl":"10.12865/CHSJ.52.01.04","url":null,"abstract":"Background: Accurate identification of pulmonary nodules as early-stage lung cancers is crucial to decrease the number of deaths and illnesses caused by lung cancer. Artificial Intelligence has the potential to enhance diagnostic accuracy and specificity in detecting lung cancer.Methods: Chest CT scanning from 300 patients with an age range between 40 and 80 years old were analysed comparing the pulmonary nodules detection rate (number of lung nodules) between AI-assisted reading, non-AI-assisted reading and the AI-system report standalone. Detected nodules, missed nodules (false negatives), and false-positive findings were analysed.Results: AI-assisted radiologists missed significantly fewer nodules (p<0.001) and achieved an almost perfect correlation (r~1.00) with expert reference values, reducing the mean absolute error (MAE) from 9.78 to 0.46. Additionally, AI increased detection sensitivity from 60% to 98% and reduced false negatives from 3,083 to 145, optimizing both diagnostic accuracy and efficiency.Conclusions: AI-assisted reading has shown to be beneficial in the detection of lung nodules compared to relying solely on radiologist observation. This suggests that an AI-powered system for evaluating lung nodules has the potential to become a valuable assistant tool in clinical practice. By combining the skills of radiologists with AI assistance, a new approach may emerge, leading to enhanced detection of lung nodules and encouraging the integration of AI in lung cancer screening initiatives.","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"52 1","pages":"30-38"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13200713/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148038740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0