Current health sciences journal最新文献

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The Role and Diagnostic Accuracy of Artificial Intelligence in Pulmonary Function Tests: A Systematic Review. 人工智能在肺功能检测中的作用和诊断准确性:系统综述。
Current health sciences journal Pub Date : 2026-04-01 Epub Date: 2026-06-30 DOI: 10.12865/CHSJ.51.02.141
Thomas Orpwood, Irina-Lavinia Soica
{"title":"The Role and Diagnostic Accuracy of Artificial Intelligence in Pulmonary Function Tests: A Systematic Review.","authors":"Thomas Orpwood, Irina-Lavinia Soica","doi":"10.12865/CHSJ.51.02.141","DOIUrl":"10.12865/CHSJ.51.02.141","url":null,"abstract":"<p><p>The rapid advancement of artificial intelligence (AI) has highlighted its potential as a supportive tool in pulmonary function test (PFT) interpretation given the inherent biological variation, inter-rater variability, lack of confidence in result interpretation and restricted access within resource-constrained settings. This study aims to systematically review the published literature on the diagnostic accuracy of AI-based interpretation of PFTs and evaluate its implications for current and future clinical practice in healthcare. After screening, forty-seven publications met the inclusion criteria and were analysed to create a narrative summary. Four main over-arching themes were identified from the available literature. AI appears to consistently outperform non-specialists in diagnostic accuracy of PFTs and showed a synergistic effect when used as an adjunct in both specialist and non-specialist settings. Using AI software also had greater diagnostic accuracy than clinicians when presented with suboptimal or limited clinical information and investigations. It was also observed that the implementation of AI can address the issue of inter-rater variability by giving more consultant interpretations. Chronic obstructive pulmonary disease diagnosis saw the greatest accuracy with other conditions such as obstructive sleep apnoea showing limited evidence for the introduction of AI as a diagnostic tool. The evidence suggests that AI has the potential to play a significant role in the future of healthcare but should be used as an adjunctive tool as opposed to an independent diagnostic decision maker. One such way it could be utilised is as a triage/screening tool to help bridge the gap between primary and secondary care.</p>","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"52 2","pages":"141-159"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13589599/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149008980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From Classroom to Clinic: A Qualitative Study on Newly Graduated Nurses' Transition to Practice. 从课堂到临床:新毕业护士向执业过渡的质性研究。
Current health sciences journal Pub Date : 2026-04-01 Epub Date: 2026-06-30 DOI: 10.12865/CHSJ.52.02.259
Hadi Jafarimanesh, Masoumeh Zakerimoghadam, Shahrzad Ghiyasvandian
{"title":"From Classroom to Clinic: A Qualitative Study on Newly Graduated Nurses' Transition to Practice.","authors":"Hadi Jafarimanesh, Masoumeh Zakerimoghadam, Shahrzad Ghiyasvandian","doi":"10.12865/CHSJ.52.02.259","DOIUrl":"10.12865/CHSJ.52.02.259","url":null,"abstract":"<p><strong>Background: </strong>The global nursing shortage and high turnover rates among newly graduated nurses (NGNs) pose significant challenges to their transition into professional roles. Understanding NGNs' experiences is crucial for identifying the factors contributing to turnover and developing targeted strategies that facilitate their integration into clinical practice, ultimately promoting long-term retention. While extensive research has explored this transition in developed countries, there remains a notable gap in studies focusing on NGNs' experiences in developing nations. This study aims to explore the lived experiences of NGNs during their transition to clinical practice (TCP), offering valuable insights to inform policy development and improve support mechanisms in healthcare settings.</p><p><strong>Design: </strong>This study employed a qualitative inductive content analysis approach to explore NGNs' transition experiences. Conducted in three hospitals affiliated with Tehran University of Medical Sciences, the study recruited 21 NGNs with less than one year of work experience through purposive sampling. Data were gathered via semi-structured face-to-face interviews and analyzed using the Graneheim and Lundman framework. To ensure the trustworthiness of findings, Lincoln and Guba's criteria were rigorously applied. Data management and analysis were facilitated by MAXQDA (version 20).</p><p><strong>Results: </strong>Three main categories emerged from the data analysis: magnetic experiences, non-magnetic experiences, and transition period outcomes.</p><p><strong>Conclusion: </strong>The findings underscore the complex and multifaceted nature of NGNs' transition experiences, encompassing both magnetic (supportive) and non-magnetic (challenging) factors that significantly influence patient care quality, job satisfaction, and retention decisions. These findings align with transition theory and transition shock models, emphasizing the urgent need for structured, evidence-based support programs to optimize the transition process. This study provides critical insights for designing targeted interventions, fostering attractive work environments, and enhancing nursing workforce retention strategies.</p>","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"52 2","pages":"259-270"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13589586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149009575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardiac Resynchronization Therapy Optimization in a Patient with Left Ventricular Non-Compaction Cardiomyopathy and Morbid Obesity. 左室非压实性心肌病合并病态肥胖患者心脏再同步化治疗优化。
Current health sciences journal Pub Date : 2026-04-01 Epub Date: 2026-06-30 DOI: 10.12865/CHSJ.52.02.280
Arsalan Farhangee, Ion Mindrila
{"title":"Cardiac Resynchronization Therapy Optimization in a Patient with Left Ventricular Non-Compaction Cardiomyopathy and Morbid Obesity.","authors":"Arsalan Farhangee, Ion Mindrila","doi":"10.12865/CHSJ.52.02.280","DOIUrl":"10.12865/CHSJ.52.02.280","url":null,"abstract":"<p><p>Left ventricular non-compaction cardiomyopathy (LVNC) is a rare myocardial disorder associated with heart failure and arrhythmias. Cardiac resynchronisation therapy (CRT) is an established treatment in patients with electrical dyssynchrony; however, achieving optimal response remains challenging in complex clinical scenarios. We report a 51-year-old male with LVNC, severe left ventricular dysfunction, morbid obesity, and recurrent atrial and ventricular arrhythmias. Despite initial improvement following CRT-D implan-tation, the patient developed progressive heart failure and recurrent ventricular tachycardia with high atrial arrhythmia burden, resulting in ineffective biventricular pacing. Following unsuccessful device optimisation strategies, a multidisciplinary decision was made to proceed with atrioventricular node ablation. This resulted in marked clinical and echocardiographic improvement, including recovery of left ventricular ejection fraction and symptomatic status. This case highlights the importance of ensuring adequate CRT delivery and demonstrates the pivot-al role of atrioventricular node ablation in patients with refractory atrial arrhythmias and suboptimal CRT response.</p>","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"52 2","pages":"281-288"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13589597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149009610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Need of Support and Guidance Among Hospitalized Patients. 住院患者对支持与指导的需求。
Current health sciences journal Pub Date : 2026-04-01 Epub Date: 2026-06-30 DOI: 10.12865/CHSJ.52.02.234
Dimitrios Kakkavas, Dimos Mastrogiannis, Angeliki Stamou, Andriana Maggita, Vasiliki Tsoulou, Athanasia Tsami, Maria Polikandrioti
{"title":"The Need of Support and Guidance Among Hospitalized Patients.","authors":"Dimitrios Kakkavas, Dimos Mastrogiannis, Angeliki Stamou, Andriana Maggita, Vasiliki Tsoulou, Athanasia Tsami, Maria Polikandrioti","doi":"10.12865/CHSJ.52.02.234","DOIUrl":"10.12865/CHSJ.52.02.234","url":null,"abstract":"<p><strong>Background: </strong>Hospitalization is a common and stressful experience that often leads to emotional distress, including anxiety and uncertainty, highlighting the need for comprehensive psychological support. It can negatively affect patients' well-being and their ability to cope with illness, underscoring the importance of addressing patients' emotional and psychosocial needs.</p><p><strong>Objective: </strong>To explore the need of support and guidance among hospitalized patients and associated factors.</p><p><strong>Methods: </strong>In the present cross-sectional study, 121 hospitalized patients were enrolled. Data collection was carried out by interview method, using the scale \"Needs of hospitalized patients with coronary artery disease scale\", which included patient characteristics. In the present study, the subscale \"need for support and guidance\" was explored. The level of statistical significance was set to p<0.05.</p><p><strong>Results: </strong>Age (p=0.001), marital status (p=0.001), occupation (p=0.003), the presence of comorbidity (p=0.001), urinary catheter use (p=0.001), previous hospitalization (p=0.001), and uncertainty regarding care after discharge (p=0.001), were found to be statistically significantly associated with need for support and guidance.</p><p><strong>Conclusion: </strong>Demographic and clinical characteristics are associated with the importance of support and guidance among hospitalized patients. In depth understanding of this need is expected to contribute to implementation of effective patient-centered care.</p>","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"52 2","pages":"234-240"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13589600/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149009635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tobacco and Color Parameters of Lateral Incisors in Young Adults. 青壮年侧切牙的烟草和颜色参数。
Current health sciences journal Pub Date : 2026-04-01 Epub Date: 2026-06-30 DOI: 10.12865/CHSJ.51.02.179
Mihaela Mociu, Gheorghe Raftu, Steliana-Gabriela Buștiuc, Cristina Gabriela Pușcașu, Cristina Bartok-Nicolae, Elena-Claudia Sin, Aureliana Caraiane
{"title":"Tobacco and Color Parameters of Lateral Incisors in Young Adults.","authors":"Mihaela Mociu, Gheorghe Raftu, Steliana-Gabriela Buștiuc, Cristina Gabriela Pușcașu, Cristina Bartok-Nicolae, Elena-Claudia Sin, Aureliana Caraiane","doi":"10.12865/CHSJ.51.02.179","DOIUrl":"10.12865/CHSJ.51.02.179","url":null,"abstract":"<p><p>This study aims to identify the disparities in tooth color between young adult consumers and non-consumers of tobacco and/or nicotine products. The study population included healthy young individuals aged 18 to 30 years. Participants were instructed to refrain from smoking for at least 2 hours before to the study session, avoid dental hygiene for a minimum of 2 hours before the session, and abstain from eating and drinking for at least 2 hours preceding the study period. A total 58 young adults participated in this study, consisting of 29 tobacco and/or nicotine users and 29 non-users. The mean lightness±standard deviation for the cervical region of tooth 1.2 was 82.25±2.841145, whereas for tooth 2.2 it was 80.55±3.625857, both derived from non-consumers in the same location. A notable disparity was observed in the a* value for teeth 1.2 in the cervical region when comparing non-consumers to users (p=0.033176). A substantial difference was noted in the central area of tooth 2.2 when comparing non-consumers to smokers (p=0.013802) for the a* values. Understanding the reasons for tooth color changes is important for early detection and accurate assessment of future treatment outcomes.</p>","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"52 2","pages":"179-184"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13589595/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149009113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From Data to Decision: Interpretable and Reliable Heart Disease Risk Prediction. 从数据到决策:可解释和可靠的心脏病风险预测。
Current health sciences journal Pub Date : 2026-04-01 Epub Date: 2026-06-30 DOI: 10.12865/CHSJ.51.02.206
Andrei-Ionuț Spînu, Renato Constantin Ivănescu, Christiana Raluca Dănciulescu, Daniel-Robert Stănescu
{"title":"From Data to Decision: Interpretable and Reliable Heart Disease Risk Prediction.","authors":"Andrei-Ionuț Spînu, Renato Constantin Ivănescu, Christiana Raluca Dănciulescu, Daniel-Robert Stănescu","doi":"10.12865/CHSJ.51.02.206","DOIUrl":"10.12865/CHSJ.51.02.206","url":null,"abstract":"<p><strong>Background: </strong>Heart disease is the leading cause of morbidity and mortality worldwide, highlighting the need for accurate and clinically meaningful risk prediction tool.</p><p><strong>Methodology: </strong>A retrospective analysis was performed on a dataset of 918 patients with complete clinical information. The relationship between variables and disease presence were explored using correlation and dependence measure. To prediction was made using logistic regression, linear discriminant analysis, and generalized additive models. The performances were evaluated using cross-validation, discrimination metrics, and calibration analysis.</p><p><strong>Results: </strong>Functional and exercise-related variables, particularly Oldpeak, maximum heart rate, chest pain type, and ST slope showed the strongest correlation with disease presence. All models achieved AUROC values higher than 0.91. Logistic regression and generalized additive models performed similarly, with no statistically significant difference between them. Calibration analysis showed a good agreement between predicted and observed probabilities.</p><p><strong>Conclusion: </strong>Heart disease prediction can be achieved with high accuracy using clinically accessible variables and interpretable models. Our findings suggest that simpler approaches remain suitable for practical clinical applications, while preserving transparency and usability.</p>","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"52 2","pages":"206-214"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13589598/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149009563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pulmonary Function in Adults with Severe Eosinophilic Asthma Using Biologicals:A Case-Control Study. 使用生物制剂治疗成人严重嗜酸性哮喘患者的肺功能:一项病例对照研究。
Current health sciences journal Pub Date : 2026-04-01 Epub Date: 2026-06-30 DOI: 10.12865/CHSJ.52.02.215
Alessandro Dos Santos Beserra, Júlio Ribeiro Borges, Isabelle da Nobrega Ferreira, Mel Portugal Cabral Santos, Thiago Thomaz Mafort, Thiago Prudente Bártholo, Agnaldo José Lopes
{"title":"Pulmonary Function in Adults with Severe Eosinophilic Asthma Using Biologicals:A Case-Control Study.","authors":"Alessandro Dos Santos Beserra, Júlio Ribeiro Borges, Isabelle da Nobrega Ferreira, Mel Portugal Cabral Santos, Thiago Thomaz Mafort, Thiago Prudente Bártholo, Agnaldo José Lopes","doi":"10.12865/CHSJ.52.02.215","DOIUrl":"10.12865/CHSJ.52.02.215","url":null,"abstract":"<p><p>The era of biologics has revolutionized the treatment of severe eosinophilic asthma (SEA). Although biologics appear to control SEA, pulmonary function is still poorly assessed with effective techniques. This study aimed to compare pulmonary function between adults living with severe asthma (alwSEA) with and without the use of biologics through a comprehensive approach to measuring pulmonary function, including assessments of pulmonary mechanics, static lung volumes, and small airways.</p><p><strong>Methodology: </strong>This is a cross-sectional study in which 15 alwSEA using biologics (biological group-BG) and 17 alwSEA using conventional therapy (control group-CG) were evaluated. These individuals underwent spirometry, body plethysmography, and respiratory oscillometry. In addition, they underwent the Asthma Control Test and the Asthma Quality of Life Questionnaire.</p><p><strong>Results: </strong>The sample was predominantly female, with 14 women (93.3%) in the BG and 16 (94.1%) in the CG. The groups differed significantly in age, with the BG being younger than the CG [52 (47-61) vs. 60 (54-66) years, p=0.045]. The BG presented significantly higher values ​​of forced expiratory volume in the first second [1.77 (1.45-1.91) vs. 1.27 (1.18-1.47) L, p=0.005]. The CG presented a higher residual volume to total lung capacity ratio [141 (128-157) vs. 108 (89-117) % predicted, p<0.001]. Respiratory system resistance at 20 Hz was higher in the CG [170 (137-216.5) vs. 131.5 (110.8-179.2) % predicted, p=0.038].</p><p><strong>Conclusions: </strong>In alwSEA, biologics appear to improve not only volumes and flows, but also air trapping. Furthermore, biologics appear to act on central airway resistance.</p>","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"52 2","pages":"215-223"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13589590/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149009605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinicopathological Features and Statistical Associations in Squamous Cell Carcinoma of the Lip. 唇部鳞状细胞癌的临床病理特征及统计学关联。
Current health sciences journal Pub Date : 2026-04-01 Epub Date: 2026-06-30 DOI: 10.12865/CHSJ.52.02.250
Ioana-Cristina Vîlcea, Bianca Cătălina Andreiana, Claudiu Mărgăritescu, Mirela Marinela Florescu, Anne-Marie Badiu, Oana Iulia Crețu, Ionuț Andrei Muraru, Alina-Maria Vîlcea, Loredana Elena Stoica, Raluca Niculina Ciurea
{"title":"Clinicopathological Features and Statistical Associations in Squamous Cell Carcinoma of the Lip.","authors":"Ioana-Cristina Vîlcea, Bianca Cătălina Andreiana, Claudiu Mărgăritescu, Mirela Marinela Florescu, Anne-Marie Badiu, Oana Iulia Crețu, Ionuț Andrei Muraru, Alina-Maria Vîlcea, Loredana Elena Stoica, Raluca Niculina Ciurea","doi":"10.12865/CHSJ.52.02.250","DOIUrl":"10.12865/CHSJ.52.02.250","url":null,"abstract":"<p><strong>Background: </strong>Lip squamous cell carcinoma (SCC) is frequently associated with chronic ultraviolet exposure and actinic cheilitis. Although prognosis is generally favorable, clinicopathological parameters may correlate with tumor characteristics and risk-related patterns.</p><p><strong>Materials and methods: </strong>A retrospective study was conducted on 21 cases of lip SCC diagnosed at the County Clinical Emergency Hospital of Craiova between January 2021 and June 2025. Epidemiological and clinical variables (age, sex, area of residence, tumor site and size, macroscopic appearance) and histopathological parameters (subtype, grade, tumor extension, resection margin status, depth of invasion, perineural and vascular invasion) were evaluated. Associations were tested using the Chi-square (χ²) tests in IBM SPSS software.</p><p><strong>Results: </strong>The mean age was 74.2±10.88 years, with male predominance (71.4%) and rural residence 71.4% of patients. Most tumors were located on the lower lip (90.4%). Keratinizing SCC was the most frequent histological subtype (61.9%), and well to moderately differentiated tumors (G1-G2) predominated. Muscular invasion was identified in 71.4% of cases, and pT3 was the most frequent (71.4%). Actinic cheilitis was present in all cases. Statistically significant associations were observed between gender and histological grade, tumor site and differentiation, and between histological subtype and degree of differentiation (p<0.05).</p><p><strong>Conclusions: </strong>Lip SCC predominantly affects elderly male patients and most frequently involves the lower lip. Tumor localization, depth of invasion, and histological grade showed relevant associations with the aggressiveness of lip SCC.</p>","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"52 2","pages":"250-258"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13589592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149009615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Influence of Ageing, Sex and Cause of Death on the Myocardial Tissue Collagen Fibrillary Component Behaviour. 年龄、性别及死亡原因对心肌组织胶原纤维成分行为的影响。
Current health sciences journal Pub Date : 2026-04-01 Epub Date: 2026-06-30 DOI: 10.12865/CHSJ.51.02.169
Laura Elena Cameniță, Cristina Florescu, Mircea-Sebastian Șerbănescu, Iancu Emil Pleșea, Răzvan Mihail Pleșea
{"title":"The Influence of Ageing, Sex and Cause of Death on the Myocardial Tissue Collagen Fibrillary Component Behaviour.","authors":"Laura Elena Cameniță, Cristina Florescu, Mircea-Sebastian Șerbănescu, Iancu Emil Pleșea, Răzvan Mihail Pleșea","doi":"10.12865/CHSJ.51.02.169","DOIUrl":"10.12865/CHSJ.51.02.169","url":null,"abstract":"<p><strong>Aim: </strong>The morphology and the function of human body are influenced by two main factors: the passing of the years and the increasing diversity of diseases with their subsequent lesions. The morphological structures of the heart are not exempt from the synergistic influence of these two major factors. The authors' goal was to compare the variations of interstitial mature collagen fibers (COLF) amount-% between the different main regions of the heart wall during patients´ ageing, on one hand, and, depending on patients' cause of death, on the other hand.</p><p><strong>Methods: </strong>Samples of myocardial tissue with no evident lesion, coming from 95 patients with different ages (0-24 years-AP_01, 25-44 years-AP_02, 45-64 years-AP_03 and >64 years-AP_04) deceased in hospital with different causes of death (vascular diseases-V_P, non-vascular diseases-NV_P, and suspect/violent cause of death-S/V_Dth) and autopsied, were collected from five epicardium-to-endocardium cross sections (left ventricle anterior wall-LV_AW, lateral wall-LV_LW and posterior wall-LV_PW, interventricular septum-IVS and right ventricle wall-RVW). Further, they were histologically processed and stained with Picro Syrius Red technique. COLF proportion was assessed, on virtual slides, with a a computer program designed specifically for this purpose. For statistical comparison of data, Kruskal-Wallis and Pearson correlation tests were used.</p><p><strong>Results: </strong>The COLF proportion had the smallest values in elderly and they increased markedly towards the younger periods of age. Then, the COLF proportion had the highest values in the RV_W (excepting the AP_04 period of life), and the lowest values in the IVS. In LV_W, COLF proportion had a general increasing trend from anterior to posterior regions in AP_01 and AP_03 periods of life and in males. In turn, it had decreasing trend from anterior to posterior regions in AP_02 and AP_04 periods of life and in females. The COLF proportion had the highest values in NV_P group in all cardiac main regions and the lowest values in V_P group (excepting LV), in both men and women. It had also the highest values in the RV_W and the lowest ones in IVS in all three diseases groups. In LV, COLF proportion had the highest values in NV_P group but the smallest ones in S-V_Dth group, in all main heart regions of this group. The COLF proportion had higher values in males than in females in all heart wall main regions in NV_P group and S-V_Dth group but vice versa in V_P group.</p><p><strong>Conclusions: </strong></p>","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"52 2","pages":"169-178"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13589587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149009626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Observational Assessment of the Effect of Sleep Bruxism on Oxyhaemoglobin Saturation:A Preliminary Study. 睡眠磨牙对氧血红蛋白饱和度影响的观察性评估:初步研究。
Current health sciences journal Pub Date : 2026-04-01 Epub Date: 2026-06-30 DOI: 10.12865/CHSJ.52.02.271
Marcelo Palinkas, Selma Siéssere, Simone Cecilio Hallak Regalo
{"title":"Observational Assessment of the Effect of Sleep Bruxism on Oxyhaemoglobin Saturation:A Preliminary Study.","authors":"Marcelo Palinkas, Selma Siéssere, Simone Cecilio Hallak Regalo","doi":"10.12865/CHSJ.52.02.271","DOIUrl":"10.12865/CHSJ.52.02.271","url":null,"abstract":"<p><strong>Objectives: </strong>Sleep bruxism, characterized by involuntary muscle activity and classified into phasic and tonic patterns, warrants analysis with respect to physiological parameters, as this could aid in understanding its broader health implications. This observational study aimed to compare oxyhaemoglobin saturation between subjects with and without sleep bruxism.</p><p><strong>Material and methods: </strong>Ninety subjects aged between 18 and 45 years, with natural permanent dentition, normal occlusion, no temporomandibular dysfunction, and no obstructive sleep apnoea, were selected and divided into two homogeneous groups regarding age, sex, weight, and height. The sleep bruxism group comprised 29 women and 16 men (mean age 30.5±6.8), as did the control group (mean age 29.4±7.9). All subjects underwent an overnight PSG session, with the diagnosis of sleep bruxism established according to the criteria of the American Academy of Sleep Medicine. Minimum, mean, and maximum oxyhaemoglobin saturation levels were evaluated using pulse oximetry. Data were analyzed using Student's t-test (p<0.05).</p><p><strong>Results: </strong>Comparisons between the groups revealed significant differences in the maximum oxyhaemoglobin saturation index (p=0.04). The sleep bruxism group showed a lower maximum oxyhaemoglobin saturation index compared to the control group. No significant differences were observed for minimum or mean oxyhaemoglobin saturation.</p><p><strong>Conclusion: </strong>Sleep bruxism was associated with a lower maximum oxyhaemoglobin saturation compared with controls. Although the observed difference was small and remained within normal physiological limits, these findings suggest a possible relationship between sleep bruxism and oxygenation dynamics during sleep that warrants further investigation.</p>","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":"52 2","pages":"271-276"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13589593/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149009590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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