Cardiology journal最新文献

{"title":"The use of artificial intelligence for predicting postinfarction myocardial viability in echocardiographic images.","authors":"Błażej Michalski, Sławomir Skonieczka, Michał Strzelecki, Michał Simiera, Karolina Kupczyńska, Ewa Szymczyk, Paulina Wejner-Mik, Piotr Lipiec, Jarosław D Kasprzak","doi":"10.5603/cj.93887","DOIUrl":"10.5603/cj.93887","url":null,"abstract":"<p><strong>Background: </strong>Evaluation of standard echocardiographic examination with artificial intelligence may help in the diagnosis of myocardial viability and function recovery after acute coronary syndrome.</p><p><strong>Methods: </strong>Sixty-one consecutive patients with acute coronary syndrome were enrolled in the present study (43 men, mean age 61 ± 9 years). All patients underwent percutaneous coronary intervention (PCI). 533 segments of the heart echo images were used. After 12 ± 1 months of follow-up, patients had an echocardiographic evaluation. After PCI each patient underwent cardiac magnetic resonance (CMR) with late enhancement and low-dose dobutamine echocardiographic examination. For texture analysis, custom software was used (MaZda 5.20, Institute of Electronics).Linear and non-linear (neural network) discriminative analyses were performed to identify the optimal analytic method correlating with CMR regarding the necrosis extent and viability prediction after follow-up. Texture parameters were analyzed using machine learning techniques: Artificial Neural Networks, Namely Multilayer Perceptron, Nonlinear Discriminant Analysis, Support Vector Machine, and Adaboost algorithm.</p><p><strong>Results: </strong>The mean concordance between the CMR definition of viability and three classification models in Artificial Neural Networks varied from 42% to 76%. Echo-based detection of non-viable tissue was more sensitive in the segments with the highest relative transmural scar thickness: 51-75% and 76-99%. The best results have been obtained for images with contrast for red and grey components (74% of proper classification). In dobutamine echocardiography, the results of appropriate prediction were 67% for monochromatic images.</p><p><strong>Conclusions: </strong>Detection and semi-quantification of scar transmurality are feasible in echocardiographic images analyzed with artificial intelligence. Selected analytic methods yielded similar accuracy, and contrast enhancement contributed to the prediction accuracy of myocardial viability after myocardial infarction in 12 months of follow-up.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"699-707"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11544410/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140923999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TELE-SPACER - a randomized clinical trial protocol: Cardioneuroablation versus pacemaker implantation in the treatment of vagally-mediated atrio-ventricular block.","authors":"Edyta Stodółkiewicz-Nowarska, Sebastian Stec, Antoni Wileczek, Przemysław Skoczyński, Kinga Gościńska-Bis, Przemysław Magielski, Magdalena Zając, Anna Ratajska, Anna Kustroń, Janusz Śledź, Wojciech Wąsek, Krzysztof Milewski","doi":"10.5603/cj.102195","DOIUrl":"10.5603/cj.102195","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"766-773"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11544413/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142483075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of xanthine oxidase inhibitors on all-cause mortality in adults: a systematic review and meta-analysis.","authors":"Marcin M Nowak, Mariusz Niemczyk, Sławomir Gołębiewski, Leszek Pączek","doi":"10.5603/cj.97807","DOIUrl":"10.5603/cj.97807","url":null,"abstract":"<p><p>Xanthine oxidase inhibitors, including allopurinol and febuxostat, are the first-line treatment of hyperuricemia. This meta-analysis investigated the association between urate-lowering therapy and all-cause mortality in different chronic diseases to match its users and non-users in a real-world setting. Overall, 11 studies were included, which reported adjusted hazard ratios for all-cause mortality over at least 12 months. Meta-analysis of all included studies showed no effect of the therapy on all-cause mortality. However, subgroup analyses showed its beneficial effect in patients with chronic kidney disease (14% risk reduction) and hyperuricemia (14% risk reduction), but not in patients with heart failure (28% risk increase). Urate-lowering therapy reduces all-cause mortality among patients with hyperuricemia and chronic kidney disease, but it seems to increase mortality in patients with heart failure and should be avoided in this subgroup.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"479-487"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11229807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141072319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myocarditis after mRNA COVID-19 vaccine administration in adult female.","authors":"Piotr Hamala, Konrad Szymczyk, Jarosław D Kasprzak","doi":"10.5603/cj.93281","DOIUrl":"10.5603/cj.93281","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":"31 1","pages":"181-182"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10919565/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140023656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insights from pulse field energy in patients with prosthetic mechanical heart valves undergoing ablation for atrial fibrillation.","authors":"Piotr Gardziejczyk, Piotr Urbanek, Andrzej Głowniak, Robert Bodalski, Marta Skowrońska, Katarzyna Wojewoda, Łukasz Szumowski, Adam Tarkowski, Jakub Baran, Michał Orczykowski","doi":"10.5603/cj.102484","DOIUrl":"10.5603/cj.102484","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"920-921"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11706272/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in the exposure to cardiovascular disease risk factors in an 18 year follow-up study of a cohort of middle age urban residents. The Polish arm of the HAPIEE study.","authors":"Magdalena Kozela, Maciej Polak, Urszula Stepaniak, Karolina Koziara, Barbara Gradowicz-Prajsnar, Andrzej Pająk","doi":"10.5603/cj.95747","DOIUrl":"10.5603/cj.95747","url":null,"abstract":"<p><strong>Background: </strong>Cross-sectional studies revealed that risk factor exposure increases with age but after reaching its peak decreases. This decline may be attributed to higher mortality among exposed individuals, lifestyle, or natural physiological changes related to age. Only prospective observations at the individual level provide credible insights of exposure during the transition from middle to old age. This study addresses changes in cardiovascular risk factors among older urban residents in Poland over an 18-year period.</p><p><strong>Methods: </strong>The study analyzed data from the Polish arm of the Health, Alcohol and Psychosocial factors In Eastern Europe (HAPIEE) project, a prospective cohort study investigating cardiovascular disease determinants. The sample included 312 participants (46-69 years). Data on demographic characteristics, blood lipids, blood pressure, body mass index (BMI), fasting glucose, and smoking status were collected at baseline and during re-examination.</p><p><strong>Results: </strong>The analysis yielded a decrease in diastolic blood pressure, total cholesterol, LDL-cholesterol, and non-HDL cholesterol concentrations. However, BMI and fasting glucose levels increased. The decrease in blood pressure was mainly attributed to treatment effects, while the reduction in lipid concentrations was observed regardless of treatment. In addition, smoking prevalence decreased over the course of 18 years.</p><p><strong>Conclusions: </strong>The results of the prospective nearly 20 year observation at the individual level confirm findings from repeated cross-sectional studies on decrease in lipid concentrations, blood pressure and prevalence of smoking in older individuals.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"690-698"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11544412/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141753553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A rare presentation of disseminated micronodular melanoma masquerading as an infiltrative cardiomyopathy.","authors":"Mariana Martinho, João Mirinha Luz, Bárbara Marques Ferreira, Inês Cruz, Oliveira Baltazar, Diogo Santos Cunha, Filipe Nogueira, Patrícia Lima, Ana Catarina Gomes, Hélder Pereira","doi":"10.5603/cj.99859","DOIUrl":"10.5603/cj.99859","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":"31 6","pages":"931-932"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11706265/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142907988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlations between soluble ST2 concentration and the nutritional status in patients with heart failure with reduced ejection fraction - cross-sectional study.","authors":"Marta Kałużna-Oleksy, Filip Waśniewski, Magdalena Szczechla, Filip Sawczak, Agata Kukfisz, Helena Krysztofiak, Katarzyna Przytarska, Ewa Straburzyńska-Migaj, Magdalena Dudek","doi":"10.5603/cj.96062","DOIUrl":"10.5603/cj.96062","url":null,"abstract":"<p><strong>Background: </strong>Heart failure (HF) is a global problem that stimulates research on markers associated with the diagnosis and course of the disease. Soluble suppression of tumorigenicity-2 (sST2) is a receptor for interleukin-33 and is associated with increased mortality rates in HF patients. Malnutrition in HF is also connected with inflammation and is associated with worse prognosis. The present study aimed to evaluate the relationship between sST2 concentration and the nutritional status of patients with HF with reduced ejection fraction (HFrEF).</p><p><strong>Material and methods: </strong>138 patients with HFrEF were enrolled in this cross-sectional study. Nutritional status was assessed using Geriatric Nutritional Risk Index (GNRI) and Controlling Nutritional Status (CONUT). The mean age was 53.6 ± 10.8 years.</p><p><strong>Results: </strong>In the group with sST2 > 32.9 ng/mL, the GNRI score was higher and the associated risk of malnutrition was more common (29% vs. 12%; p = 0.011). Coherently in the group with sST2 > 32.9 ng/mL the median CONUT score was worse (2 [IQR 1-3] vs. 1 [IQR 0-2]; p = 0.0016) and the risk of malnutrition defined by this tool was also more prevalent (p = 0.0079). This relationship was independent of the concentration of natriuretic peptides, age and sex.</p><p><strong>Conclusions: </strong>According to available research, this research is the first study showing that sST2 concentration is related with nutritional status in HFrEF patients. sST2 may help to evaluate the necessity for nutritional intervention in HFrEF patients.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"850-860"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11706252/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140923940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoplasmic reticulum stress and expression of nitric oxide synthases in heart failure with preserved and with reduced ejection fraction - pilot study.","authors":"Karol Momot, Małgorzata Wojciechowska, Kamil Krauz, Katarzyna Czarzasta, Liana Puchalska, Maciej Zarębiński, Agnieszka Cudnoch-Jędrzejewska","doi":"10.5603/cj.97962","DOIUrl":"10.5603/cj.97962","url":null,"abstract":"<p><strong>Background: </strong>Unfolded Protein Response (UPR), endoplasmic reticulum (ER) stress, and inducible nitric oxide synthase (iNOS) overexpression have been found to influence heart failure with preserved ejection fraction (HFpEF) pathogenesis. Their importance in heart failure with reduced ejection fraction (HFrEF) is not entirely established; there is little data involving a detailed comparison between HFpEF and HFrEF from this perspective. This pilot study aimed to compare circulating levels of Glucose-regulated protein 78kDa (GRP78) (ER - stress marker) and all NOS isoforms between both HFpEF and HFrEF and to analyze the correlation between these markers and the clinical characteristics of the patients.</p><p><strong>Methods: </strong>Forty-two patients with HFpEF and thirty-eight with HFrEF were involved in this study. Clinical characteristics and echocardiographic data were obtained. Basic laboratory tests were performed and ELISA tests for iNOS, endothelial NOS (eNOS), neuronal NOS (nNOS), and GRP78.</p><p><strong>Results: </strong>Patients with HFpEF had lower circulating levels of GRP78 and higher iNOS concentrations when compared to HFrEF patients (P = 0.023, P < 0.0001, accordingly). The subgroup of the HFpEF population with eGFR < 60 mL/min/1.73m2 had higher nNOS and eNOS levels than HFpEF patients with normal GFR (P = 0.049, P = 0.035, respectively). In the HFrEF subgroup, patients with coexistent diabetes mellitus had elevated concentrations of nNOS compared to the subpopulation without diabetes mellitus (P = 0.041). There was a positive correlation between eNOS and nNOS concentrations (ρ = 0.86, P < 0.0001).</p><p><strong>Conclusions: </strong>In HFpEF, there is a more intensified iNOS overexpression, while in HFrEF, ER stress is more prominent.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"885-894"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11706269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparison of the management and five-year outcomes of patients treated for chronic coronary syndrome between 2006-2007 and 2015-2016 - insights from the PRESAGE registry.","authors":"Izabela Kozłowska-Karaca, Piotr Desperak, Mariusz Gąsior, Przemysław Trzeciak","doi":"10.5603/cj.100464","DOIUrl":"10.5603/cj.100464","url":null,"abstract":"<p><strong>Background: </strong>Changes in the management of patients with chronic coronary syndromes (CCS) require continuous monitoring of results of treatment in daily clinical practice. The present study contains a comparison of the clinical characteristics, management, and in-hospital and five-year outcomes of patients with CCS enrolled on the Prospective REgistry of Stable AnGina management and trEatment (PRESAGE).</p><p><strong>Methods: </strong>A group of 3475 patients with CCS were selected who underwent coronary angiography and were divided into two groups who were treated in the years 2006-2007 (1300 [37.4%]) - group I, and during 2015-2016 (2175 [62.6%] - group II). The composite endpoints involved death, non-fatal myocardial infarction (MI), and acute coronary syndrome-driven revascularization.</p><p><strong>Results: </strong>Comparing patients from group I to those from group II, group I were younger; 61.8 (54.9-68.5) vs. 66.1 (59.7-72.7) years respectively, with a higher incidence of previous MI and percutaneous intervention. Patients from the group II had a higher incidence of hypertension, diabetes, obesity, atrial fibrillation, New York Heart Association class III or more. The incidence of the composite endpoints did not vary significantly between the two groups during the entire period after the index hospitalization, but patients from the group I had a lower mortality rate both within three and five years after discharge (8.5% vs. 10.7, p = 0.03 and 13.2% vs. 17.9%, p < 0.001, respectively).</p><p><strong>Conclusions: </strong>Patients treated during 2006-2007 and 2015-2016 differed in age, clinical characteristics, and comorbidities. The composite endpoint incidence was similar in both groups,butlong-term mortality rates werehigherin the 2015-2016 cohort.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"823-832"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11706261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142514608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}