Sylwia Iwańczyk, Kamil Bujak, Rafał Wolny, Adam Janas, Miłosz Dziarmaga, Maksymilian P Opolski, Rafał Januszek, Adrian Włodarczak, Piotr Desperak, Piotr Niezgoda, Michał Kryjak, Mariusz Tomaniak, Zenon Huczek, Michał Hawranek, Bernardo Cortese, Wojciech Wańha
{"title":"Are we at dawn of the drug-coated balloons era? Current evidence, future directions, and tasks of the newly established working group of the Association of Cardiovascular Interventions.","authors":"Sylwia Iwańczyk, Kamil Bujak, Rafał Wolny, Adam Janas, Miłosz Dziarmaga, Maksymilian P Opolski, Rafał Januszek, Adrian Włodarczak, Piotr Desperak, Piotr Niezgoda, Michał Kryjak, Mariusz Tomaniak, Zenon Huczek, Michał Hawranek, Bernardo Cortese, Wojciech Wańha","doi":"10.5603/cj.98927","DOIUrl":"10.5603/cj.98927","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":"31 4","pages":"507-511"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11374319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142115901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiology journalPub Date : 2024-01-01Epub Date: 2023-10-12DOI: 10.5603/cj.92243
Katarzyna Major, Aleksandra Bodys-Pełka, Marcin Grabowski, Małgorzata Lelonek
{"title":"Quality of life in heart failure: New data, new drugs and devices.","authors":"Katarzyna Major, Aleksandra Bodys-Pełka, Marcin Grabowski, Małgorzata Lelonek","doi":"10.5603/cj.92243","DOIUrl":"10.5603/cj.92243","url":null,"abstract":"<p><p>Quality of life (QoL) is a therapeutic goal in heart failure. There are many EBM therapies for improving QoL. In this study, data is presented on new pharmacotherapies and devices that impact QoL in the heart failure population.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"156-167"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10919569/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41223564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiology journalPub Date : 2024-01-01Epub Date: 2022-04-04DOI: 10.5603/CJ.a2022.0014
Eryka Karbowska, Damian Swieczkowski, Aleksandra Gasecka, Michal Pruc, Kamil Safiejko, Jerzy R Ladny, Tomasz Kopiec, Milosz J Jaguszewski, Krzysztof J Filipiak, Zubaid Rafique, Lukasz Szarpak
{"title":"Statins and the risk of pancreatic cancer: A systematic review and meta-analysis of 2,797,186 patients.","authors":"Eryka Karbowska, Damian Swieczkowski, Aleksandra Gasecka, Michal Pruc, Kamil Safiejko, Jerzy R Ladny, Tomasz Kopiec, Milosz J Jaguszewski, Krzysztof J Filipiak, Zubaid Rafique, Lukasz Szarpak","doi":"10.5603/CJ.a2022.0014","DOIUrl":"10.5603/CJ.a2022.0014","url":null,"abstract":"<p><strong>Background: </strong>Statin use in many studies is related to the improvement of a patients' condition including reducing the risk of various malignancies. Herein, is a systematic review and meta-analysis to examine the evidence on the association between statin therapy and the risk of the occurrence of pancreatic cancer, mainly in terms of decreased risk of developing pancreatic cancer among patients using statin therapy in the long-term perspective.</p><p><strong>Methods: </strong>PubMed, Web of Science, Scopus and Cochrane Central Register of Controlled Trials (CENTRAL) were searched from database inception to December 1st, 2021. Random effect models were used to estimate summary odds ratios (OR) and the corresponding 95% confidence intervals (CI).</p><p><strong>Results: </strong>A total of 26 studies comprising 2,797,186 patients were included. Polled analysis showed that pancreatic cancer occurrence in statin vs. no-statin group varied and amounted to 0.4% vs. 0.6% (RR = 0.83; 95% CI: 0.72-0.96; I² = 84%; p = 0.01).</p><p><strong>Conclusions: </strong>In summary, the present analysis shows that overall statins use is significantly associated with a reduction in risk of pancreatic cancer. However, these results were not confirmed for the randomized controlled trial subgroup. Further prospective studies are needed to confirm the current results.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"243-250"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11076033/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46352304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bivalirudin versus heparin in contemporary percutaneous coronary interventions for patients with acute coronary syndrome: a systematic review and meta-analysis.","authors":"Junyan Zhang, Zhongxiu Chen, Duolao Wang, Chen Li, Fangbo Luo, Yong He","doi":"10.5603/cj.90956","DOIUrl":"10.5603/cj.90956","url":null,"abstract":"<p><strong>Background: </strong>Bivalirudin is associated with fewer major bleeding events than heparin in patients undergoing percutaneous coronary intervention (PCI), but confounding effects of concomitant glycoprotein IIb/IIIa inhibitors, routine femoral artery access, and less potent effects of clopidogrel limits meaningful comparisons. The present study is a systematic review and meta-analysis to compare bivalirudin to heparin in contemporary practice.</p><p><strong>Methods: </strong>The Cochrane Library, PubMed, EMBASE, and Ovid MEDLINE databases were searched for relevant studies, including comparisons between bivalirudin and heparin in the current medical era from inception to December 23, 2021. Studies reporting incidences of major adverse cardiac events (MACE) and net adverse clinical events (NACE) in patients undergoing PCI and meeting the inclusion criteria were retained. Data extraction was performed by three independent reviewers.</p><p><strong>Results: </strong>The meta-analysis included 8 studies. Compared to heparin, bivalirudin during PCI was associated with a lower NACE risk, lower all-cause death, and similar MACE risk, with a pooled risk ratio of 0.82 (95% confidence interval [CI] 0.69-0.97, p = 0.02), 0.83 (95% CI 0.74-0.94, p = 0.002), and 0.93 (95% CI 0.78-1.10, p = 0.38), respectively. Moreover, the reduction in NACE was mainly attributed to reduced bleeding (22% reduction in the risk of major bleeding, 95% CI 0.63-0.97, p = 0.03).</p><p><strong>Conclusions: </strong>These findings suggest that bivalirudin use during PCI reduced the risk of NACE and all-cause death but did not reduce the risk of MACE compared with heparin use in PCI. More studies specifically designed for anticoagulation strategies and a personalized anticoagulation regimen to comprehensively balance bleeding and ischemia risks are required.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"309-320"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11076038/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107593124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Current understanding of Duchenne muscular dystrophy - a purported interview with a purported expert.","authors":"Jarosław Meyer-Szary, Szymon Mikulski","doi":"10.5603/cj.94330","DOIUrl":"10.5603/cj.94330","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":"31 3","pages":"367-368"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11229802/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141473591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiology journalPub Date : 2024-01-01Epub Date: 2024-01-22DOI: 10.5603/cj.96161
Jerzy Sacha, Krzysztof Krawczyk, Przemysław Lipski, Piotr Feusette, Marek Gierlotka
{"title":"Percutaneous transaxillary approach for balloon aortic valvuloplasty and complex percutaneous coronary intervention with Impella support.","authors":"Jerzy Sacha, Krzysztof Krawczyk, Przemysław Lipski, Piotr Feusette, Marek Gierlotka","doi":"10.5603/cj.96161","DOIUrl":"10.5603/cj.96161","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"174-176"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10919560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139514395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiology journalPub Date : 2024-01-01Epub Date: 2023-10-19DOI: 10.5603/cj.97253
Marcin D Drozd, Michał Tkaczyszyn, Monika Kasztura, Kinga Węgrzynowska-Teodorczyk, Irena Flinta, Waldemar Banasiak, Piotr Ponikowski, Ewa A Jankowska
{"title":"Intravenous iron supplementation improves energy metabolism of exercising skeletal muscles without effect on either oxidative stress or inflammation in male patients with heart failure with reduced ejection fraction.","authors":"Marcin D Drozd, Michał Tkaczyszyn, Monika Kasztura, Kinga Węgrzynowska-Teodorczyk, Irena Flinta, Waldemar Banasiak, Piotr Ponikowski, Ewa A Jankowska","doi":"10.5603/cj.97253","DOIUrl":"10.5603/cj.97253","url":null,"abstract":"<p><strong>Background: </strong>Skeletal muscle dysfunction is a feature of heart failure (HF). Iron deficiency (ID) is prevalent in patients with HF associated with exercise intolerance and poor quality of life. Intravenous iron in iron deficient patients with HF has attenuated HF symptoms, however the pathomechanisms remain unclear. The aim of study was to assess whether intravenous iron supplementation as compared to placebo improves energy metabolism of skeletal muscles in patients with HF.</p><p><strong>Methods: </strong>Men with heart failure with reduced ejection fraction (HFrEF) and ID were randomised in 1:1 ratio to either intravenous ferric carboxymaltose (IV FCM) or placebo. In vivo reduction of lactates by exercising skeletal muscles of forearm was analyzed. A change in lactate production between week 0 and 24 was considered as a primary endpoint of the study.</p><p><strong>Results: </strong>There were two study arms: the placebo and the IV FCM (12 and 11 male patients with HFrEF). At baseline, there were no differences between these two study arms. IV FCM therapy as compared to placebo reduced the exertional production of lactates in exercising skeletal muscles. These effects were accompanied by a significant increase in both serum ferritin and transferrin saturation in the IV FCM arm which was not demonstrated in the placebo arm.</p><p><strong>Conclusions: </strong>Intravenous iron supplementation in iron deficient men with HFrEF improves the functioning of skeletal muscles via an improvement in energy metabolism in exercising skeletal muscles, limiting the contribution of anaerobic reactions generating ATP as reflected by a lower in vivo lactate production in exercising muscles in patients with repleted iron stores.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"300-308"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11076021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49686257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiology journalPub Date : 2024-01-01Epub Date: 2024-01-22DOI: 10.5603/cj.95175
Aleksandra Chabior, Agata Tymińska, Agnieszka Pawlak, Andrea Giordani, Alida Caforio, Marcin Grabowski, Krzysztof Ozierański
{"title":"Advances in myocarditis management in the light of the latest research and recent guidelines of the European Society of Cardiology.","authors":"Aleksandra Chabior, Agata Tymińska, Agnieszka Pawlak, Andrea Giordani, Alida Caforio, Marcin Grabowski, Krzysztof Ozierański","doi":"10.5603/cj.95175","DOIUrl":"10.5603/cj.95175","url":null,"abstract":"<p><p>Myocarditis remains an unknown disease with varying clinical manifestations, often leading to heart failure. The latest 2021 and 2022 guidelines of the European Society of Cardiology (ESC) are the first official European documents updating knowledge on the diagnosis and treatment of myocarditis since the 2013 ESC expert consensus statement. These guidelines and new studies allow standardization and improvements to the management of myocarditis. In this review, we discuss the most important aspects of myocarditis diagnosis, therapies and follow-up based on current knowledge.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"342-351"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11076022/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139514388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jacek Klaudel, Wojciech Trenkner, Krzysztof Pawłowski, Piotr Radowski, Dariusz Surman, Bartłomiej Ziniewicz, Michał Smolarczyk, Urszula Kossakowska-Jemioło, Włodzimierz Krasowski
{"title":"Large-bore SOFIA catheter for bailout thrombus aspiration in STEMI.","authors":"Jacek Klaudel, Wojciech Trenkner, Krzysztof Pawłowski, Piotr Radowski, Dariusz Surman, Bartłomiej Ziniewicz, Michał Smolarczyk, Urszula Kossakowska-Jemioło, Włodzimierz Krasowski","doi":"10.5603/cj.95375","DOIUrl":"10.5603/cj.95375","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":"31 2","pages":"352-354"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11076029/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140874372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}