Cardiology journal最新文献

The effect of P2Y12 receptor inhibitors on clinical outcomes in patients with acute coronary syndrome undergoing primary percutaneous intervention and receiving abciximab. P2Y12受体抑制剂对急性冠状动脉综合征患者经皮介入治疗并接受阿昔单抗治疗的临床结局的影响

Cardiology journal Pub Date : 2025-06-24 DOI: 10.5603/cj.104531

Onur Altınkaya, Selim Aydemir, Murat Özmen, Sidar Şiyar Aydın, Emrah Aksakal, Mustafa Özkoç, Rauf Macit, İbrahim Saraç, Yavuzer Koza, Muhammet Hakan Taş

{"title":"The effect of P2Y12 receptor inhibitors on clinical outcomes in patients with acute coronary syndrome undergoing primary percutaneous intervention and receiving abciximab.","authors":"Onur Altınkaya, Selim Aydemir, Murat Özmen, Sidar Şiyar Aydın, Emrah Aksakal, Mustafa Özkoç, Rauf Macit, İbrahim Saraç, Yavuzer Koza, Muhammet Hakan Taş","doi":"10.5603/cj.104531","DOIUrl":"https://doi.org/10.5603/cj.104531","url":null,"abstract":"Background: Our study compared the effect of P2Y12 receptor inhibitors in combination with abciximab on clinical outcomes in patients with acute coronary syndrome (ACS).Methods: Our study is retrospective, consisting of 852 consecutive ACS patients who presented to our clinic between 2015 and 2021, underwent primary percutaneous coronary intervention (PCI), and received abciximab in addition to dual antiplatelet therapy. The P2Y12 receptor inhibitors were compared in terms of in-hospital and 1-year major adverse cardiac events (MACE), and clinically significant in-hospital and 1-year bleeding complications.Results: The patients' mean age was 60.4 ± 11 years, and 702 (82.4%) were male. In-hospital MACE, in-hospital mortality, 1-year MACE, and 1-year mortality were significantly higher in the clopidogrel group compared to the ticagrelor group. There was no significant difference in the development of in-hospital and 1-year bleeding between clopidogrel and the more potent P2Y12 receptor inhibitors. According to the BARC score, there was no difference in major bleeding between ticagrelor and clopidogrel (p = 0.641), but minor bleeding was significantly lower in the ticagrelor group (p < 0.001). In logistic regression analysis, the 1-year MACE rate was lower in the potent P2Y12 receptor inhibitors group compared to clopidogrel. At the same time, no association was found with short- and long-term mortality, bleeding, or in-hospital MACE.Conclusions: In our study, potent P2Y12 receptor inhibitors combined with abciximab decreased 1-year MACE without significantly increasing bleeding in ACS patients undergoing PCI compared to clopidogrel. This study suggests that potent P2Y12 receptor inhibitors can be safely used with abciximab, considering the bleeding risk.","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intracoronary adrenaline for the treatment of refractory no-reflow phenomenon: A single-centre experience. 冠状动脉内肾上腺素治疗难治性无血流现象：单中心经验。

Cardiology journal Pub Date : 2025-06-12 DOI: 10.5603/cj.102975

Piotr Desperak, Marcin Osuch, Jarosław Madowicz, Justyna Małyszek-Tumidajewicz, Elżebieta Wojtynek, Michał Hawranek

引用次数: 0

The relationship between inspiratory muscle strength and exercise tolerance in patients with coronary heart disease. 冠心病患者吸气肌力量与运动耐量的关系。

Cardiology journal Pub Date : 2025-06-12 DOI: 10.5603/cj.102835

Tao Shen, Jinglin Li, Yanxin Song, Chuan Ren, Wei Zhao

{"title":"The relationship between inspiratory muscle strength and exercise tolerance in patients with coronary heart disease.","authors":"Tao Shen, Jinglin Li, Yanxin Song, Chuan Ren, Wei Zhao","doi":"10.5603/cj.102835","DOIUrl":"https://doi.org/10.5603/cj.102835","url":null,"abstract":"Background: There has been insufficient research on the assessment of exercise capacity in patients with coronary heart disease (CHD) following percutaneous coronary intervention (PCI) who exhibit inspiratory muscle weakness (IMW).Methods: A retrospective cohort study involving CHD patients who underwent PCI at Peking University Third Hospital Heart Rehabilitation Center between January 2019 and December 2021 was conducted. Patients who had undergone inspiratory muscle testing and cardiopulmonary exercise testing (CPET) were included, and their clinical data were collected and analyzed.Results: A total of 571 post-PCI CHD patients were included in the study. The average age was 60.8 ± 4.3 years, and 479 male patients (83.9%) were included. The average maximal inspiratory pressure (MIP) of the enrolled patients was 90.7 ± 26.1 cm H₂O, with 56 patients (9.8%) presenting with IMW. The IMW group had lower peak oxygen uptake (VO₂peak) (17.4 ± 4.2 vs. 19.3 ± 5.1 ml/min/kg, P < 0.001) and oxygen uptake efficiency slopes (OUES) (1464.7 ± 368.5 vs. 1619.2 ± 400.4, P=0.004). MIP correlated with VO₂peak (r = 0.719, P < 0.001) and OUES (r = 0.622, P < 0.001). Multivariate regression analysis revealed that VO₂peak (OR = 0.917, 95% CI = 0.858 ~ 0.980) and history of chronic obstructive pulmonary disease (COPD) (OR = 1.705, 95% CI = 0.934 ~ 3.112) were independent risk factors for IMW.Conclusions: After PCI, CHD patients exhibiting IMW, especially those with comorbid COPD, demonstrated reduced exercise tolerance and oxygen uptake efficiency.","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Continuous mechanical aspiration thrombectomy for STEMI with high thrombus burden. 高血栓负荷STEMI患者持续机械抽吸取栓。

Cardiology journal Pub Date : 2025-06-12 DOI: 10.5603/cj.102528

Sylwia Sławek-Szmyt, Aleksander Araszkiewicz, Marek Grygier, Maciej Lesiak

引用次数: 0

Patient-tailored stent: are we there yet? 患者定制支架：我们做到了吗？

Cardiology journal Pub Date : 2025-06-12 DOI: 10.5603/cj.103757

Piotr Arski, Jakub M Zimodro, Magda Mucha, Paweł Jańczak, Arkadiusz Pietrasik, Aleksandra Gąsecka

{"title":"Patient-tailored stent: are we there yet?","authors":"Piotr Arski, Jakub M Zimodro, Magda Mucha, Paweł Jańczak, Arkadiusz Pietrasik, Aleksandra Gąsecka","doi":"10.5603/cj.103757","DOIUrl":"https://doi.org/10.5603/cj.103757","url":null,"abstract":"Percutaneous coronary intervention (PCI) has become a routine revascularization strategy. PCI outcome is affected by patient- and procedure-related factors. Stent design has evolved to overcome the risk of thrombosis and restenosis associated with stent implantation. Bare metal stents were followed by two generations of drug-eluting stents with different strut sizes, polymer types, and antiproliferative drug classes. Modern technologies comprising polymer-free stents, bioresorbable vascular scaffolds, and titanium-nitride-oxide-coated stents are intensively studied. The choice of the appropriate stent is crucial for PCI success, especially in high-risk settings. Hence, to establish a strategy for patient-tailored stent choice, we aimed to discuss the efficacy and safety of coronary stents in specific procedural and clinical scenarios. We concluded that the current evidence may encourage the use of (i) sirolimus-eluting stents (SES) in small vessel disease, (ii) biodegradable-polymer SES in multivessel PCI, (iii) everolimus-eluting stents (EES) and zotarolimus-eluting stents in bifurcation lesions, (iv) EES in chronic total occlusions, (v) SES, EES, and polymer-free stents in diabetic patients, (vi) ultrathin biodegradable-polymer DES and titanium-nitride-oxide-coated stents in acute coronary syndrome, and (vii) polymer-free biolimus-eluting stents in high bleeding-risk patients. Further randomized trials are required to established firm recommendations.","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rehabilitation in convalescent COVID-19 subjects improves right ventricular function. 康复期COVID-19患者的右心室功能改善

Cardiology journal Pub Date : 2025-06-03 DOI: 10.5603/cj.103070

Nektarios Souvaliotis, Angelos Vontetsianos, Maria-Ioanna Gounaridi, Nikolaos Chynkiamis, Ourania Katsarou, Artemis Anastasiou, Stamatios Lampsas, Ioannis Gialamas, Panagiotis Theofilis, Antonios Lysandrou, George Marinos, Evangelos Oikonomou, Manolis Vavuranakis, Gerasimos Siasos

引用次数: 0

Single-stage pulmonary vein isolation combined with percutaneous implantation of left atrial appendage occluder in patients with recent onset ischemic stroke and atrial fibrillation (PILOS-AF): a study protocol of randomized controlled trial. 单期肺静脉隔离联合经皮左房附件封堵器治疗初发缺血性卒中合并心房颤动（PILOS-AF）：一项随机对照试验研究方案

Cardiology journal Pub Date : 2025-06-03 DOI: 10.5603/cj.104167

Maciej T Wybraniec, Andrzej Hoffmann, Tomasz Bochenek, Michał Lelek, Marcin Wita, Krzysztof Szydło, Anetta Lasek-Bal, Mariusz Gąsior, Zbigniew Kalarus, Paweł Ptaszyński, Jarosław Kaźmierczak, Katarzyna Mizia-Stec, Krystian Wita

引用次数: 0

Aspiration thrombectomy compared to catheter directed thrombolysis in pulmonary embolism: outcomes from a tertiary referral center. 吸入取栓与导管溶栓在肺栓塞中的比较：来自三级转诊中心的结果。

Cardiology journal Pub Date : 2025-06-03 DOI: 10.5603/cj.99047

Amine Al Soueidy, Gregory Miller, Shawana Hussain, Jean-Sebastien Rachoin, Krystal Hunter, Elias Iliadis

{"title":"Aspiration thrombectomy compared to catheter directed thrombolysis in pulmonary embolism: outcomes from a tertiary referral center.","authors":"Amine Al Soueidy, Gregory Miller, Shawana Hussain, Jean-Sebastien Rachoin, Krystal Hunter, Elias Iliadis","doi":"10.5603/cj.99047","DOIUrl":"https://doi.org/10.5603/cj.99047","url":null,"abstract":"Background: Prompt treatment of pulmonary embolism (PE) prevents morbidity and mortality. The aim of the present study was to evaluate and compare the effectiveness of two FDA-approved catheter-based therapies (CBT) for acute PE: ultrasound-assisted catheter-directed thrombolysis EKOS (EKOS Corporation, Bothell, WA) and Penumbra Indigo aspiration thrombectomy (Penumbra Inc., Alameda, CA, USA).Methods: Patients with submassive and massive PE who underwent CBT between 09/2014 and 08/2022 at our institution were identified. Primary efficacy outcome was change in the echocardiographic RV/LV diameter ratio within 48 to 72h of the procedure.Results: A total of 189 patients underwent EKOS (n=119) or Penumbra (n = 70) for submassive (n = 175) and massive (n = 14) PE. The RV/LV ratio showed improvement post intervention, with 21.2% decrease in the EKOS group (EG) and 35.6% in the Penumbra group (PG). PG group had a greater reduction in RV/LV (median change 0.396 (IQR, 0.347) vs. 0.207 (IQR, 0.306), p < 0.001). The rate of complications and in-hospital mortality were similar (15.1% in EG and 10% in PG and 2.5% in EG, 4.3% in PG, p = 0.672; respectively). Subgroup analysis comparing responders, defined as patients with a post-intervention echocardiographic RV/LV ratio < 0.9, and non-responders showed a lower rate of chronic lung disease, (4.3% vs. 19.0%, p = 0.015).Conclusions: Both CBT options are promising for treating acute submassive or massive PE, with efficacy outcomes favoring aspiration thrombectomy. Presence of chronic lung disease was associated with lower response to CBT in terms of reversal of RV dysfunction. Longer follow-up and randomized controlled trials are needed for definitive conclusions.","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Temporal trends in incidence and mortality of Infective endocarditis caused by oral streptococci. 口腔链球菌引起的感染性心内膜炎的发病率和死亡率的时间趋势。

Cardiology journal Pub Date : 2025-06-02 DOI: 10.5603/cj.101505

Paula Anguita Gámez, Juan C Castillo Dominguez, Jose Lopez Aguilera, Rafael Gonzalez Manzanares, Manuel Pan Alvarez-Ossorio, Manuel Anguita Sanchez

引用次数: 0

Preclinical safety and performance evaluation of a highly-flexible peripheral polytetrafluoroethylene-covered stent. 高柔性聚四氟乙烯外周支架的临床前安全性和性能评价。

Cardiology journal Pub Date : 2025-05-30 DOI: 10.5603/cj.91079

Armando Tellez, Marta Mazur, Mateusz Kachel, Adam Janas, Carlos Fernandez, Karolina Łukasik, Sabrina N Evans, Juliana Castro, Eduardo Cordeiro, Luciano Curado, Piotr Buszman

{"title":"Preclinical safety and performance evaluation of a highly-flexible peripheral polytetrafluoroethylene-covered stent.","authors":"Armando Tellez, Marta Mazur, Mateusz Kachel, Adam Janas, Carlos Fernandez, Karolina Łukasik, Sabrina N Evans, Juliana Castro, Eduardo Cordeiro, Luciano Curado, Piotr Buszman","doi":"10.5603/cj.91079","DOIUrl":"https://doi.org/10.5603/cj.91079","url":null,"abstract":"Background: Sten graft implantation faces challenges such as deliverability issues, fracture risk, and subsequent restenosis. Recent advancements have introduced thinner coatings for increased flexibility and improved biocompatibility. The aim herein was to assess the safety and performance of a highly flexible cobalt-chromium stent covered with polytetrafluoroethylene (PTFE) in a preclinical model.Methods: In total 6 PTEF-covered stent grafts 6mm x 38mm cobalt-chromium, (Solaris BXTM, Scitech Produtos Medicos) were implanted compared to 5 controls ( BeGraftTM, Bentley InnoMed GmbH) in the iliac arteries of 11 swine. Stents were evaluated with angiography, high-definition IVUS, and histology for 28 days.Results: All animals underwent successful implantation with 100% survival at follow-up. At 28 days, there was no statistically significant difference in MLD compared to baseline in both groups (test, 5.2 ± 0.7 mm vs 5.3 ± 0.6 mm, p = 0.8; control, 4.9 ± 0.7 mm vs 5.1 ± 0.5 mm, p = 0.8), indicating no LLL (test, -0.2 ± 0.16 vs control, -0.18 ± 0.16 mm; p = 0.8). IVUS revealed a tendency for the less neointimal area in the test group (3.75 ± 0.9mm² vs 5.69 ± 2.2 mm²; p = 0.08), resulting in a tendency toward higher % AS in the control arm (14.07 ± 3.42% vs 20 ± 7%; p = 0.1). Microscopic evaluation revealed minimal vascular injury (test 0.1 ± 0.3 vs control 0.1 ± 0.1) and complete endothelialization coverage (test, 3.2 ± 0.8 vs control 3.8 ± 0.3) in both groups, with minimal inflammation(test vs. control: per strut 0.02 ± 0.06 vs. 0.14 ± 0.22; neointimal 1.2 ± 0.6 vs 1.1 ± 0.4; medial 0.3 ± 0.4 vs 0.3 ± 0.4).Conclusion: Solaris BXTM demonstrated highly flexible and biocompatible, with minimal vascular injury, and reduced neointimal hyperplasia compared to the control.","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0