Cardiology journal最新文献

The impact of shock therapy on depression development and remote prognosis in cardiac resynchronization therapy recipients.

Cardiology journal Pub Date : 2024-12-20 DOI: 10.5603/cj.101837

Tomasz Podolecki, Robert Pudlo, Michał Mazurek, Monika Kozieł-Siołkowska, Joanna Boidol, Oskar Kowalski, Radosław Lenarczyk, Zbigniew Kalarus

{"title":"The impact of shock therapy on depression development and remote prognosis in cardiac resynchronization therapy recipients.","authors":"Tomasz Podolecki, Robert Pudlo, Michał Mazurek, Monika Kozieł-Siołkowska, Joanna Boidol, Oskar Kowalski, Radosław Lenarczyk, Zbigniew Kalarus","doi":"10.5603/cj.101837","DOIUrl":"https://doi.org/10.5603/cj.101837","url":null,"abstract":"Background: The aim of this study was to assess the incidence and clinical significance of depression in patients with cardiac resynchronization therapy with an implantable cardioverter-defibrillator (CRT-D). The study was also to evaluate the impact of shock therapy on depression development and long-term prognosis.Methods: The prospective study encompassed 396 consecutive heart failure (HF) patients implanted with CRT-D. All patients completed the Beck Depression Inventory (BDI-II) and underwent a psychiatric examination at baseline. 221 patients free of depressive symptoms at baseline were included into the final analysis. The assessment of psychiatric status was routinely repeated every 6 months as well as after the shock delivery. The primary outcome was a composite endpoint of death or hospitalization for HF.Results: During long-term observation (median 37.1 months) 52 (23.5%) patients suffered from an implantable cardioverter-defibrillator (ICD) shock, whereas 48 (21.8%) subjects developed depression. The incidence of new-onset depression was significantly higher in patients after shock delivery (Shock Group), CRT non-responders and subjects with atrial fibrillation. The risk for a composite endpoint was higher in the Shock Group than subjects without an ICD intervention: 57.7% vs. 25.4% and in patients with new-onset depression compared to the population free of this disorder: 62.5% vs. 24.9% (all p < 0.001). New-onset depression (HR 1.7) and an ICD shock (HR 2.1) were strong independent predictors of poor prognosis.Conclusions: Depression is a common mental disorder in CRT-D recipients, that adversely affects long-term prognosis. Subjects suffering from ICD shocks and those with HF progression are at higher risk of experiencing depressive symptoms.","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Differences in coronary microcirculation measurements during regadenoson vs. adenosine - induced hyperemia.

Cardiology journal Pub Date : 2024-12-20 DOI: 10.5603/cj.97857

Rafał Januszek, Wojciech Siłka, Natalia Bukała, Michał Chyrchel, Wojciech Wańha, Andrzej Surdacki, Stanisław Bartuś

{"title":"Differences in coronary microcirculation measurements during regadenoson vs. adenosine - induced hyperemia.","authors":"Rafał Januszek, Wojciech Siłka, Natalia Bukała, Michał Chyrchel, Wojciech Wańha, Andrzej Surdacki, Stanisław Bartuś","doi":"10.5603/cj.97857","DOIUrl":"https://doi.org/10.5603/cj.97857","url":null,"abstract":"Background: Little is known about the similarity of microcirculation assessment outcomes performed with regadenoson and adenosine. The aim of the current study was to compare coronary flow reserve (CFR) and index of microcirculatory resistance (IMR) assessment using adenosine and regadenoson, and to evaluate predictors regarding the size of differences.Methods: 44 patients were enrolled and diagnosed between 2021 and 2023. Fractional flow reserve (FFR), CFR and IMR were measured twice in the circumflex (Cx) (n = 8) or left anterior descending (LAD) (n = 36) artery: once with continuous infusion of adenosine (Adenocor 140 µg/kg/min) and 10 minutes later with regadenoson (Rapiscan 400 µg i.v.).Results: Averaged results were quantified with adenosine and regadenoson for FFR (0.81 [0.75 ÷ 0.89] vs. 0.80 [0.73 ÷ 0.88]), CFR (3.84 [1.67 ÷ 4.08] vs. 3.97 [1.78 ÷ 4.32]) and IMR (20.01 [11 ÷ 24.5] vs. 20.25 [10.75 ÷ 23]), respectively. None of the differences were statistically significant. Among the significant (p < 0.05) predictors of greater ΔCFR, the following can be noted: prior percutaneous transluminal angioplasty/carotid artery stenting (β = 2.35), oral anticoagulant usage (β = 0.89), and prior stroke/transient ischaemic attack (TIA) (β = 1.09), with the latter being also confirmed for greater ΔIMR (β = 8.89). Moreover, patients with New York Heart Association (NYHA) class II/III, as compared to those with NYHA class I, were more likely to have greater ΔIMR (β = 11.89).Conclusions: Regadenoson may be a feasible alternative to adenosine in coronary microcirculation assessment, as it produces similar outcomes. Selected factors were found to be predictors of greater differences in IMR, CFR and FFR values according to the agent used for coronary hyperemia.","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rationale and design of the MICE study: exploration of the temporal relation between electrical and mechanical events during myocardial ischemia.

Cardiology journal Pub Date : 2024-12-03 DOI: 10.5603/cj.98481

Niya Mileva, Teodora Yaneva-Sirakova, Irina Hristova, Despina Georgieva, Greta Koleva, Dimitra Psalla, Ranko Georgiev, Dobrin Vassilev

引用次数: 0

Insights from pulse field energy in patients with prosthetic mechanical heart valves undergoing ablation for atrial fibrillation.

Cardiology journal Pub Date : 2024-12-02 DOI: 10.5603/cj.102484

Piotr Gardziejczyk, Piotr Urbanek, Andrzej Głowniak, Robert Bodalski, Marta Skowrońska, Katarzyna Wojewoda, Łukasz Szumowski, Adam Tarkowski, Jakub Baran, Michał Orczykowski

引用次数: 0

A novel, patient-tailored method for non-invasive iFRCT measurement.

Cardiology journal Pub Date : 2024-11-29 DOI: 10.5603/cj.100509

Anna Nieroda, Krzysztof Jankowski, Janusz Domański, Michał Janiszewski, Marcin Komorowski, Krzysztof Lamparski, Janusz Kochman, Alekandra Gąsecka, Marek Pawlikowski

引用次数: 0

Silent cerebral ischemic lesions in ablation-naïve patients with non-valvular atrial fibrillation: does the pulmonary vein anatomy matter? 未经消融治疗的非瓣膜性心房颤动患者的无声脑缺血病变：肺静脉解剖结构是否重要？

Cardiology journal Pub Date : 2024-11-26 DOI: 10.5603/cj.99142

Andrzej Głowniak, Anna Drelich-Zbroja, Adam Tarkowski, Paweł Marzęda, Katarzyna Wojewoda, Katarzyna Wysokińska, Anna Wysocka, Monika Miazga, Anna Jaroszyńska, Krzysztof Kaczmarek, Andrzej Jaroszyński, Michał Orczykowski

{"title":"Silent cerebral ischemic lesions in ablation-naïve patients with non-valvular atrial fibrillation: does the pulmonary vein anatomy matter?","authors":"Andrzej Głowniak, Anna Drelich-Zbroja, Adam Tarkowski, Paweł Marzęda, Katarzyna Wojewoda, Katarzyna Wysokińska, Anna Wysocka, Monika Miazga, Anna Jaroszyńska, Krzysztof Kaczmarek, Andrzej Jaroszyński, Michał Orczykowski","doi":"10.5603/cj.99142","DOIUrl":"https://doi.org/10.5603/cj.99142","url":null,"abstract":"Background: Silent cerebral ischemic lesions (SCILs) detected by magnetic resonance imaging (MRI) can precede symptomatic stroke, the risk of which is increased five-fold in atrial fibrillation (AF) patients. In our study, we aimed to evaluate the initial incidence of SCILs in the population of patients referred for ablation due to symptomatic AF and to identify possible risk factors.Methods: A total of 110 patients, with a mean age (SD) of 59.9 (9.4) years, referred for ablation, were included in the study. In all patients, MRI was performed before the procedure to evaluate the incidence of SCILs in the ablation-naïve patients.Results: MRI revealed preexisting SCIL in 81/110 patients (73.6%). Notably, SCILs were found in all patients with CHA₂DS₂-VASc score ≥ 4. In univariable analysis, age (p < 0.001), CHA₂DS₂-VASc score (p = 0.001), hypertension (p = 0.01), and anticoagulation duration (p = 0.023) were identified as significant risk factors for SCILs, while the presence of anatomical variants of left-sided common pulmonary veins trunk (LCPV) had negative prognostic value (p = 0.026). Multivariable logistic regression analysis identified age (p < 0.001) as the risk factor of preexisting SCILs, whereas the presence of LCPV trunk was associated with significantly lower (p = 0.005) SCILs incidence.Conclusions: Silent cerebral ischemic lesions detected in MRI are frequent in the population of patients with non-valvular AF. The incidence of SCILs is higher in patients with long history of arrhythmia and higher CHA₂DS₂-VASc score. The relationship between the anatomy of pulmonary veins and the incidence of SCILs needs further investigation.","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142718049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

GENTLE-PACE - A multicenter, randomized, double-blinded research study comparinG the Efficacy and safety of cardioNeuroablaTion vs. permanent pacing in patients with an implantabLE PACEmaker for symptomatic bradycardia. GENTLE-PACE--一项多中心、随机、双盲研究，比较了植入 PACE 起搏器治疗症状性心动过缓患者的心脏神经起搏与永久起搏的有效性和安全性。

Cardiology journal Pub Date : 2024-11-25 DOI: 10.5603/cj.100718

Przemysław Skoczyński, Bruno Hrymniak, Bartosz Skonieczny, Bartosz Biel, Krystian Josiak, Bartosz Krakowiak, Kuba Ptaszkowski, Krzysztof S Gołba, Jacek Bednarek, Jarosław Kosior, Edyta Stodółkiewicz-Nowarska, Anna Skotny, Patrycja Aktanorowicz, Agnieszka Andrejków, Anna Ratajska, Magdalena Zając, Waldemar Banasiak, Adrian Doroszko, Dorota Zyśko, Sebastian Stec, José Carlos Pachón-Mateos, Dariusz Jagielski

引用次数: 0

Transcatheter mitral valve replacement - a new option for a selected group of patients? 经导管二尖瓣置换术--特定患者群体的新选择？

Cardiology journal Pub Date : 2024-11-21 DOI: 10.5603/cj.99752

Mariusz Kuśmierczyk, Adam Witkowski, Michał Zembala, Bogusław Kapelak, Marcin Gruchała, Andrzej Gackowski, Marek Deja, Wojciech Wojakowski, Marek Grygier, Marcin Grabowski, Ewa Kowalik, Piotr Przygodzki, Maciej Niewada, Michał Jakubczyk

{"title":"Transcatheter mitral valve replacement - a new option for a selected group of patients?","authors":"Mariusz Kuśmierczyk, Adam Witkowski, Michał Zembala, Bogusław Kapelak, Marcin Gruchała, Andrzej Gackowski, Marek Deja, Wojciech Wojakowski, Marek Grygier, Marcin Grabowski, Ewa Kowalik, Piotr Przygodzki, Maciej Niewada, Michał Jakubczyk","doi":"10.5603/cj.99752","DOIUrl":"https://doi.org/10.5603/cj.99752","url":null,"abstract":"Mitral regurgitation (MR) is the second most common valvular disease. Symptomatic MR is associated with a poor prognosis. Cardiac surgery is recommended in the severe form of the disease. If the surgical risk is high or functional mitral regurgitation repair/replacement cannot be combined with aorto-coronary bypass graft surgery, a transcatheter edge-to-edge valve repair should be considered. Currently, there is no recommended procedure in patients with severe symptomatic MR, high cardiac surgical risk, and low probability of success or contraindications to the percutaneous edge-to-edge treatment. A recent alternative is the mitral valve implantation using a transapical approach or through the interatrial septum. Currently, the only CE-marked transcatheter bioprothesis valve using transapical approach and implanted without extracorporeal circulation support is the Tendyne valve. This paper discusses the safety, clinical efficacy and cost effectiveness of this valve and the size of the target population in Poland. The clinical efficacy was evaluated in a study of 100 patients with severe symptomatic MR. The total 2-year mortality was 39%. The hospitalisation rate due to heart failure decreased from 1.3 events/year prior to the surgery to 0.51. MR was not recorded in 93.2% of the survivors. An economic analysis accounting for the survival, health-related quality of life, and the risk of hospitalisation due to heart failure showed that the Tendyne system is cost-effective compared to pharmacological treatment: the incremental cost-utility ratio equalled 93,324-110,696 PLN, depending on the approach, clearly below the official threshold in Poland. The annual number of eligible patients was estimated at 60.","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diuretic treatment using the RenalGuard® system in patients hospitalized due to acute decompensated heart failure and characterization of the profile of patients with good and poor response to treatment - preliminary study. 使用 RenalGuard® 系统对急性失代偿性心力衰竭住院患者进行利尿治疗，并对治疗效果好和不好的患者进行特征分析--初步研究。

Cardiology journal Pub Date : 2024-11-21 DOI: 10.5603/cj.102386

Paweł Siwołowski, Piotr Gajewski, Mateusz Sokolski, Robert Zymliński, Mateusz Guzik, Joanna Szachniewicz, Piotr Ponikowski

{"title":"Diuretic treatment using the RenalGuard® system in patients hospitalized due to acute decompensated heart failure and characterization of the profile of patients with good and poor response to treatment - preliminary study.","authors":"Paweł Siwołowski, Piotr Gajewski, Mateusz Sokolski, Robert Zymliński, Mateusz Guzik, Joanna Szachniewicz, Piotr Ponikowski","doi":"10.5603/cj.102386","DOIUrl":"https://doi.org/10.5603/cj.102386","url":null,"abstract":"Background: The aim of the study was to analyze the potential relationship between the diuretic response, the clinical profile and the concentrations of selected biochemical markers and to identify a group of patients who will benefit from a new form of therapy combining standard diuretic therapy with the use of a RenalGuard® system.Methods: This is a retrospective study of 19 patients (mean age 67 ± 10 years, 95% men) hospitalized due to acute decompensated heart failure (ADHF, NYHA class III-IV, BP 125 ± 14/73 ± 16 mmHg, eGFR 58 ± 24) with persistent overhydration despite standard therapy. A targeted comparative analysis of selected clinical and biochemical parameters was performed to determine the parameters associated with a better diuretic response [good diuretic responders (GDR) group].Results: The good diuretic responders group had significantly lower levels of creatinine (1.23 ± 0.4 vs. 1.69 ± 0.35, p = 0.025) magnesium 0.70 ± 0.14 vs. 0.83 ± 0.09, p = 0.030) and blood urea nitrogen (BUN, 28 ± 11 vs. 39 ± 10, p = 0.045). Additionally, in GDR group a statistically significant greater ability to dilute urine in the 12th and 24th hour of therapy was found.Conclusions: The results of the study indicate the potential use of the RenalGuard® system in combination with standard intravenous diuretic therapy for controlled dehydration in the treatment of a selected group of patients with ADHF. It is advisable to identify the detailed mechanisms of GDR and characterize this group of patients more precisely.","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The importance of etiologic factor identification in patients with infective endocarditis - results of tertiary center analysis (2015-2023). 感染性心内膜炎患者病因识别的重要性--三级中心分析结果（2015-2023 年）。

Cardiology journal Pub Date : 2024-11-21 DOI: 10.5603/cj.99587

Robert Morawiec, Aleksander Misiewicz, Paweł Bollin, Michał Kośny, Michał Krejca, Jarosław Drożdż

引用次数: 0