Cardiology journalPub Date : 2024-01-01Epub Date: 2024-07-08DOI: 10.5603/cj.93499
Xinjian Li, Lin Mi, Juntao Duan, Liyuan Tao, Xinye Xu, Guisong Wang
{"title":"Murray law-based quantitative flow ratio for assessment of nonculprit lesions in patients with ST-segment elevation myocardial infarction.","authors":"Xinjian Li, Lin Mi, Juntao Duan, Liyuan Tao, Xinye Xu, Guisong Wang","doi":"10.5603/cj.93499","DOIUrl":"10.5603/cj.93499","url":null,"abstract":"<p><strong>Introduction: </strong>Revascularization of nonculprit arteries in patients with ST-Segment Elevation Myocardial Infarction (STEMI) is now recommended based on several trials. However, the optimal therapeutic strategy of nonculprit lesions remains unknown. Murray law-based Quantitative Flow Ratio (μQFR) is a novel, non-invasive, vasodilator-free method for evaluating the functional severity of coronary artery stenosis, which has potential applications for nonculprit lesion assessment in STEMI patients.</p><p><strong>Material and methods: </strong>Patients with STEMI who received staged PCI before hospital discharge were enrolled retrospectively. μQFR analyses of nonculprit vessels were performed based on both acute and staged angiography.</p><p><strong>Results: </strong>Eighty-four patients with 110 nonculprit arteries were included. The mean acute μQFR was 0.76 ± 0.18, and the mean staged μQFR was 0.75 ± 0.19. The average period between acute and staged evaluation was 8 days. There was a good correlation (r = 0.719, P < 0.001) between acute μQFR and staged μQFR. The classification agreement was 89.09%. The area under the receiver operator characteristic (ROC) curve for detecting staged μQFR ≤ 0.80 was 0.931.</p><p><strong>Conclusions: </strong>It is feasible to calculate the μQFR during the acute phase of STEMI patients. Acute μQFR and staged μQFR have a good correlation and agreement. The μQFR could be a valuable method for assessing functional significance of nonculprit arteries in STEMI patients.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"522-527"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11374328/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141556140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiology journalPub Date : 2024-01-01Epub Date: 2024-09-17DOI: 10.5603/cj.102158
Grzegorz Gajos
{"title":"SELECT semaglutide to improve outcomes in patients with obesity and cardiovascular disease, also without diabetes.","authors":"Grzegorz Gajos","doi":"10.5603/cj.102158","DOIUrl":"10.5603/cj.102158","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"782-783"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11544414/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142303389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiology journalPub Date : 2024-01-01Epub Date: 2023-12-27DOI: 10.5603/cj.94123
Maciej Dyrbuś, Anna Kurek, Katarzyna Sokoła, Jacek T Niedziela, Mateusz Ostręga, Daniel Cieśla, Mariusz Gąsior, Mateusz Tajstra
{"title":"Low-temperature electrocautery for high-risk cardiac implantable electronic device procedures.","authors":"Maciej Dyrbuś, Anna Kurek, Katarzyna Sokoła, Jacek T Niedziela, Mateusz Ostręga, Daniel Cieśla, Mariusz Gąsior, Mateusz Tajstra","doi":"10.5603/cj.94123","DOIUrl":"10.5603/cj.94123","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"171-173"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10919561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139041043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lipoprotein(a): an important consideration for DAPT therapy after PCI.","authors":"Kongyong Cui, Kefei Dou","doi":"10.5603/cj.98494","DOIUrl":"10.5603/cj.98494","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":"31 2","pages":"365-366"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11076024/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140861298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiology journalPub Date : 2024-01-01Epub Date: 2024-09-03DOI: 10.5603/cj.97069
Wojciech Siłka, Zbigniew Siudak, Krzysztof P Malinowski, Wojciech Wańha, Tomasz Pawłowski, Arkadiusz Pietrasik, Janusz Sielski, Karol Kaziród-Wolski, Łukasz Kołtowski, Wojciech Wojakowski, Jacek Legutko, Stanisław Bartuś, Rafał Januszek
{"title":"Risk factors of cardiac arrest during a percutaneous coronary intervention performed with rotational atherectomy - analysis based on a Large National Registry.","authors":"Wojciech Siłka, Zbigniew Siudak, Krzysztof P Malinowski, Wojciech Wańha, Tomasz Pawłowski, Arkadiusz Pietrasik, Janusz Sielski, Karol Kaziród-Wolski, Łukasz Kołtowski, Wojciech Wojakowski, Jacek Legutko, Stanisław Bartuś, Rafał Januszek","doi":"10.5603/cj.97069","DOIUrl":"10.5603/cj.97069","url":null,"abstract":"<p><strong>Background: </strong>Rotational atherectomy (RA) is traditionally administered for patients with heavily calcified lesions and is thereby characterized by a high risk of the performed intervention. However, the prevalence characteristics of cardiac arrest are poorly studied in this group of patients. We aimed to evaluate the frequency and risk factors of cardiac arrest during percutaneous coronary interventions (PCI) performed with RA and preceding coronary angiography (CA).</p><p><strong>Methods: </strong>Based on the data collected in the Polish Registry of Invasive Cardiology Procedures (ORPKI) from 2014 to 2021, we included 6522 patients who were treated with RA-assisted PCI. We scrutinized patient and procedural characteristics, as well as periprocedural complications, subsequently comparing groups in terms of cardiac arrest incidence with the use of univariable and multivariable analyses.</p><p><strong>Results: </strong>Thirty-five (0.5%) patients suffered from cardiac arrest during RA-PCI or preceding CA. They were characterized by significantly higher rates of prior stroke, acute coronary syndromes (ACS) as indications and higher Killip class (P < 0.001) at the admission time. Among the confirmed independent predictors of in-procedure cardiac arrest, the following can be noted: factors related to patients' clinical characteristics (e.g., older age, female sex, and disease burden), periprocedural characteristics (e.g., PCI within left main coronary artery [LMCA]), and periprocedural complications (e.g., coronary artery perforation and no-reflow phenomenon).</p><p><strong>Conclusions: </strong>Severe clinical condition at baseline, expressed by ACS presence and Killip class IV, as well as RA-PCI performed within LMCA and other periprocedural complications, were the strongest predictors of cardiac arrest during RA-assisted PCI and CA.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"785-793"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11706255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142121334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiology journalPub Date : 2024-01-01Epub Date: 2024-11-21DOI: 10.5603/cj.99752
Mariusz Kuśmierczyk, Adam Witkowski, Michał Zembala, Bogusław Kapelak, Marcin Gruchała, Andrzej Gackowski, Marek Deja, Wojciech Wojakowski, Marek Grygier, Marcin Grabowski, Ewa Kowalik, Piotr Przygodzki, Maciej Niewada, Michał Jakubczyk
{"title":"Transcatheter mitral valve replacement - a new option for a selected group of patients?","authors":"Mariusz Kuśmierczyk, Adam Witkowski, Michał Zembala, Bogusław Kapelak, Marcin Gruchała, Andrzej Gackowski, Marek Deja, Wojciech Wojakowski, Marek Grygier, Marcin Grabowski, Ewa Kowalik, Piotr Przygodzki, Maciej Niewada, Michał Jakubczyk","doi":"10.5603/cj.99752","DOIUrl":"10.5603/cj.99752","url":null,"abstract":"<p><p>Mitral regurgitation (MR) is the second most common valvular disease. Symptomatic MR is associated with a poor prognosis. Cardiac surgery is recommended in the severe form of the disease. If the surgical risk is high or functional mitral regurgitation repair/replacement cannot be combined with aorto-coronary bypass graft surgery, a transcatheter edge-to-edge valve repair should be considered. Currently, there is no recommended procedure in patients with severe symptomatic MR, high cardiac surgical risk, and low probability of success or contraindications to the percutaneous edge-to-edge treatment. A recent alternative is the mitral valve implantation using a transapical approach or through the interatrial septum. Currently, the only CE-marked transcatheter bioprothesis valve using transapical approach and implanted without extracorporeal circulation support is the Tendyne valve. This paper discusses the safety, clinical efficacy and cost effectiveness of this valve and the size of the target population in Poland. The clinical efficacy was evaluated in a study of 100 patients with severe symptomatic MR. The total 2-year mortality was 39%. The hospitalisation rate due to heart failure decreased from 1.3 events/year prior to the surgery to 0.51. MR was not recorded in 93.2% of the survivors. An economic analysis accounting for the survival, health-related quality of life, and the risk of hospitalisation due to heart failure showed that the Tendyne system is cost-effective compared to pharmacological treatment: the incremental cost-utility ratio equalled 93,324-110,696 PLN, depending on the approach, clearly below the official threshold in Poland. The annual number of eligible patients was estimated at 60.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"895-905"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11706262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiology journalPub Date : 2024-01-01Epub Date: 2023-12-27DOI: 10.5603/cj.98214
Raymond Farah, Rola Khamisy-Farah, Kacper Dziedzic, Ewa Skrzypek, Michal Pruc, Nicola Luigi Bragazzi, Lukasz Szarpak, Mahmoud Jomah
{"title":"The role of the neutrophil-lymphocyte ratio in predicting poor outcomes in COVID-19 patients.","authors":"Raymond Farah, Rola Khamisy-Farah, Kacper Dziedzic, Ewa Skrzypek, Michal Pruc, Nicola Luigi Bragazzi, Lukasz Szarpak, Mahmoud Jomah","doi":"10.5603/cj.98214","DOIUrl":"10.5603/cj.98214","url":null,"abstract":"<p><strong>Background: </strong>This study examines how the neutrophil-lymphocyte ratio (NLR) predicts coronavirus disease 2019 (COVID-19) hospitalization, severity, length, and mortality in adult patients.</p><p><strong>Methods: </strong>A study was done using a retrospective, single-center, observational design. A total of 400 patients who were admitted to the Ziv Medical Center (Safed, Israel) from April 2020 to December 2021 with a confirmed diagnosis of COVID-19 through RT-PCR testing were included in the analysis. Two complete blood count laboratory tests were conducted for each patient. The first test was administered upon admission to the hospital, while the second test was conducted prior to the patient's discharge from the hospital or a few days before their death.</p><p><strong>Results: </strong>Four hundred patients were included in the study, 206 males (51.5%) and 194 females (48.5%). The mean age was 64.5 ± 17.1 years. In the group of cases, there were 102 deaths, and 296 survivors were recorded, with a fatality rate of 25.5%. The median NLR was 6.9 ± 5.8 at the beginning of hospitalization and 15.1 ± 32.9 at the end of hospitalization (p < 0.001). The median length of hospital stay was 9.4 ± 8.8 days. NLR in the fatality group was 34.0 ± 49.9 compared to 8.4 ± 20.4 in the survivor group (p < 0.001). Comparison between the NLR at the time of admission of the patient and before discharge/death was 6.9 ± 5.8 vs. 15.1 ± 32.9 (p < 0.001).</p><p><strong>Conclusions: </strong>The analyses conducted revealed a statistically significant correlation between the NLR and the severity, mortality rates, and the duration of hospitalization. The consideration of NLR should commence during the initial phases of the disease when assessing individuals afflicted with COVID-19.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"374-380"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11229800/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139041070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiology journalPub Date : 2024-01-01Epub Date: 2024-01-30DOI: 10.5603/cj.95969
Paweł Derejko, Jacek Kuśnierz, Aleksander Bardyszewski, Michał Orczykowski, Dobromiła Dzwonkowska, Magdalena Polańska-Skrzypczyk, Łukasz Jan Szumowski
{"title":"Cryoballoon ablation without use of contrast for the treatment of paroxysmal atrial fibrillation.","authors":"Paweł Derejko, Jacek Kuśnierz, Aleksander Bardyszewski, Michał Orczykowski, Dobromiła Dzwonkowska, Magdalena Polańska-Skrzypczyk, Łukasz Jan Szumowski","doi":"10.5603/cj.95969","DOIUrl":"10.5603/cj.95969","url":null,"abstract":"<p><strong>Background: </strong>Cryoballoon ablation (CBA) for atrial fibrillation (AF) is usually preceded by demonstrating pulmonary vein (PV) occlusion using contrast. The aim of the study was to determine efficacy and safety of a simplified protocol for CBA performed without demonstrating PV occlusion and compare achieved results with conventional CBA.</p><p><strong>Methods: </strong>Paroxysmal AF patients undergoing a first-time CBA were prospectively included. In the non-contrast (NC) group CBA was performed using standardized protocol without demonstrating PV occlusion. In the conventional contrast (CC) group ablations were performed after confirmation of PV occlusion.</p><p><strong>Results: </strong>The NC and CC groups comprised 51 and 22 patients, respectively. PVI according to the group assignment was achieved in 34 (67%) and 21 (95.5%) patients from the NC and CC groups, respectively (p < 0.001). In the NC group, 184 (90%) out of 204 veins were isolated without venography. There were no differences between the NC and CC groups in terms of procedure duration (89.7 ± 22.6 vs. 90.0 ± 20.6 min; p = 0.7) and fluoroscopy time (15.3 ± 6.3 vs. 15 ± 4.5 min; p = 0.8). In the NC group, the use of contrast was significantly lower compared to the CC group (4.9 ± 10.1 vs. 19.4 ± 8.6 mL, p < 0.001). There were no serious adverse events in both groups. A 1-year freedom from AF was achieved in 73.5% and 71.5% of patients from the NC and CC groups, respectively (p = 1).</p><p><strong>Conclusions: </strong>Cryoballoon ablation without demonstrating vein occlusion with contrast is safe and feasible. Proposed simplified approach enables isolation of the vast majority of pulmonary veins with a significant reduction in the amount of contrast used.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"665-674"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11229812/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139577155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}