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Cryoballoon ablation without use of contrast for the treatment of paroxysmal atrial fibrillation. 不使用造影剂的低温球囊消融术治疗阵发性心房颤动。
Cardiology journal Pub Date : 2024-01-01 Epub Date: 2024-01-30 DOI: 10.5603/cj.95969
Paweł Derejko, Jacek Kuśnierz, Aleksander Bardyszewski, Michał Orczykowski, Dobromiła Dzwonkowska, Magdalena Polańska-Skrzypczyk, Łukasz Jan Szumowski
{"title":"Cryoballoon ablation without use of contrast for the treatment of paroxysmal atrial fibrillation.","authors":"Paweł Derejko, Jacek Kuśnierz, Aleksander Bardyszewski, Michał Orczykowski, Dobromiła Dzwonkowska, Magdalena Polańska-Skrzypczyk, Łukasz Jan Szumowski","doi":"10.5603/cj.95969","DOIUrl":"10.5603/cj.95969","url":null,"abstract":"<p><strong>Background: </strong>Cryoballoon ablation (CBA) for atrial fibrillation (AF) is usually preceded by demonstrating pulmonary vein (PV) occlusion using contrast. The aim of the study was to determine efficacy and safety of a simplified protocol for CBA performed without demonstrating PV occlusion and compare achieved results with conventional CBA.</p><p><strong>Methods: </strong>Paroxysmal AF patients undergoing a first-time CBA were prospectively included. In the non-contrast (NC) group CBA was performed using standardized protocol without demonstrating PV occlusion. In the conventional contrast (CC) group ablations were performed after confirmation of PV occlusion.</p><p><strong>Results: </strong>The NC and CC groups comprised 51 and 22 patients, respectively. PVI according to the group assignment was achieved in 34 (67%) and 21 (95.5%) patients from the NC and CC groups, respectively (p < 0.001). In the NC group, 184 (90%) out of 204 veins were isolated without venography. There were no differences between the NC and CC groups in terms of procedure duration (89.7 ± 22.6 vs. 90.0 ± 20.6 min; p = 0.7) and fluoroscopy time (15.3 ± 6.3 vs. 15 ± 4.5 min; p = 0.8). In the NC group, the use of contrast was significantly lower compared to the CC group (4.9 ± 10.1 vs. 19.4 ± 8.6 mL, p < 0.001). There were no serious adverse events in both groups. A 1-year freedom from AF was achieved in 73.5% and 71.5% of patients from the NC and CC groups, respectively (p = 1).</p><p><strong>Conclusions: </strong>Cryoballoon ablation without demonstrating vein occlusion with contrast is safe and feasible. Proposed simplified approach enables isolation of the vast majority of pulmonary veins with a significant reduction in the amount of contrast used.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11229812/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139577155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Severe angulation of the descending aorta with a kink: Buddy wire is key for a successful transfemoral transcatheter aortic valve replacement. 降主动脉严重成角并出现扭结:Buddy导丝是经口主动脉瓣置换术成功的关键。
Cardiology journal Pub Date : 2024-01-01 DOI: 10.5603/cj.100462
Sarah Mauler-Wittwer, Marc Arcens, Stephane Noble
{"title":"Severe angulation of the descending aorta with a kink: Buddy wire is key for a successful transfemoral transcatheter aortic valve replacement.","authors":"Sarah Mauler-Wittwer, Marc Arcens, Stephane Noble","doi":"10.5603/cj.100462","DOIUrl":"10.5603/cj.100462","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11544408/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impella-supported endovascular repair of thoracoabdominal aorta dissection. Impella支持的胸腹主动脉夹层血管内修复术。
Cardiology journal Pub Date : 2024-01-01 DOI: 10.5603/cj.99067
Arkadiusz Pietrasik, Aleksandra Gąsecka, Michał Gawlik, Dawid Tomasik, Krzysztof Lamparski, Katarzyna Jama, Tomasz Jakimowicz
{"title":"Impella-supported endovascular repair of thoracoabdominal aorta dissection.","authors":"Arkadiusz Pietrasik, Aleksandra Gąsecka, Michał Gawlik, Dawid Tomasik, Krzysztof Lamparski, Katarzyna Jama, Tomasz Jakimowicz","doi":"10.5603/cj.99067","DOIUrl":"10.5603/cj.99067","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11374329/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142115902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of successful versus failed percutaneous coronary intervention in patients with chronic total occlusion: A systematic review and meta-analysis. 慢性完全闭塞患者经皮冠状动脉介入治疗成功与失败的比较:一项系统综述和荟萃分析。
Cardiology journal Pub Date : 2024-01-01 Epub Date: 2022-03-04 DOI: 10.5603/CJ.a2022.0010
Dongfeng Zhang, Nan Nan, Yuguo Xue, Mingduo Zhang, Jinfan Tian, Changzhe Chen, Min Zhang, Xiantao Song
{"title":"Comparison of successful versus failed percutaneous coronary intervention in patients with chronic total occlusion: A systematic review and meta-analysis.","authors":"Dongfeng Zhang, Nan Nan, Yuguo Xue, Mingduo Zhang, Jinfan Tian, Changzhe Chen, Min Zhang, Xiantao Song","doi":"10.5603/CJ.a2022.0010","DOIUrl":"10.5603/CJ.a2022.0010","url":null,"abstract":"<p><strong>Background: </strong>The optimal treatment strategy of chronic total occlusion (CTO) is currently debated. This meta-analysis aimed to evaluate the long-term clinical outcomes of successful percutaneous coronary intervention (PCI) of CTO.</p><p><strong>Methods: </strong>Electronic databases were searched for studies comparing long-term outcomes between successful PCI in patients with CTO using drug-eluting stents and failed procedures. Meta-analysis was conducted with major adverse cardiac events (MACE) and all-cause mortality during the longest follow-up as endpoints. The combined hazard ratios (HRs) were applied to assess the correlation between successful CTO PCI and MACE/all-cause mortality.</p><p><strong>Results: </strong>Eight studies consisting of 6,211 patients published between 2012 and 2020 met our inclusion criteria, and the CTO PCI success rate was 81.2%. Patients in the failed group were much older, and more likely to have morbidities (hypertension and prior myocardial infarction), reduced left ventricular ejection fraction, and severe lesion characteristics (multivessel disease and moderate/severe calcification). Pooled results indicated that successful CTO PCI was significantly associated with prognosis. Compared to failed recanalization, patients receiving successful procedures had an improved MACE (HR: 0.50, 95% CI: 0.40-0.61, p < 0.001). Subgroup analyses further revealed the prognostic value of successful CTO PCI. However, no difference was observed regarding all-cause mortality (HR: 0.79, 95% CI: 0.61-1.02, p = 0.074).</p><p><strong>Conclusions: </strong>The present study showed that CTO recanalization was associated with improved long-term outcomes. However, randomized trials are needed to confirm the results due to the mismatch of baseline characteristics.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10919558/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47455539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A giant primary monophasic synovial sarcoma in the mediastinum. 纵隔内巨大的原发性单相滑膜肉瘤。
Cardiology journal Pub Date : 2024-01-01 DOI: 10.5603/cj.92292
Lang Gao, Lin He, Yixia Lin, Mingxing Xie, Yuman Li
{"title":"A giant primary monophasic synovial sarcoma in the mediastinum.","authors":"Lang Gao, Lin He, Yixia Lin, Mingxing Xie, Yuman Li","doi":"10.5603/cj.92292","DOIUrl":"10.5603/cj.92292","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10919577/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140023655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic accuracy of a novel optical coherence tomography-based fractional flow reserve algorithm for assessment of coronary stenosis significance. 一种新的基于光学相干层析的分数血流储备算法用于评估冠状动脉狭窄意义的诊断准确性。
Cardiology journal Pub Date : 2024-01-01 Epub Date: 2023-11-15 DOI: 10.5603/cj.90744
Weili Pan, Wenjuan Wei, Yumeng Hu, Li Feng, Yongkui Ren, Xinsheng Li, Changling Li, Jun Jiang, Jianping Xiang, Xiaochang Leng, Da Yin
{"title":"Diagnostic accuracy of a novel optical coherence tomography-based fractional flow reserve algorithm for assessment of coronary stenosis significance.","authors":"Weili Pan, Wenjuan Wei, Yumeng Hu, Li Feng, Yongkui Ren, Xinsheng Li, Changling Li, Jun Jiang, Jianping Xiang, Xiaochang Leng, Da Yin","doi":"10.5603/cj.90744","DOIUrl":"10.5603/cj.90744","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to introduce a novel optical coherence tomography-derived fractional flow reserve (FFR) computational approach and assess the diagnostic performance of the algorithm for assessing physiological function.</p><p><strong>Methods: </strong>The fusion of coronary optical coherence tomography and angiography was used to generate a novel FFR algorithm (AccuFFRoct) to evaluate functional ischemia of coronary stenosis. In the current study, a total of 34 consecutive patients were included, and AccuFFRoct was used to calculate the FFR for these patients. With the wire-measured FFR as the reference standard, we evaluated the performance of our approach by accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV).</p><p><strong>Results: </strong>Per vessel accuracy, sensitivity, specificity, PPV, and NPV for AccuFFRoct in identifying hemodynamically significant coronary stenosis were 93.8%, 94.7%, 92.3%, 94.7%, and 92.3%, respectively, were found. Good correlation (Pearson's correlation coefficient r = 0.80, p < 0.001) between AccuFFRoct and FFR was observed. The Bland-Altman analysis showed a mean difference value of -0.037 (limits of agreement: -0.189 to 0.115). The area under the receiver-operating characteristic curve (AUC) of AccuFFRoct in identifying physiologically significant stenosis was 0.94, which was higher than the minimum lumen area (MLA, AUC = 0.91) and significantly higher than the diameter stenosis (%DS, AUC = 0.78).</p><p><strong>Conclusions: </strong>This clinical study shows the efficiency and accuracy of AccuFFRoct for clinical implementation when using invasive FFR measurement as a reference. It could provide important insights into coronary imaging superior to current methods based on the degree of coronary artery stenosis.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11229798/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107593126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dedicated devices for non-invasive cardiovascular risk assessment - the future of cardiovascular prevention. 无创心血管风险评估专用设备--心血管预防的未来。
Cardiology journal Pub Date : 2024-01-01 Epub Date: 2024-05-20 DOI: 10.5603/cj.96477
Bartosz Rolek, Ewelina Błażejowska, Grzegorz Procyk, Jakub Michał Zimodro, Aleksandra Gąsecka
{"title":"Dedicated devices for non-invasive cardiovascular risk assessment - the future of cardiovascular prevention.","authors":"Bartosz Rolek, Ewelina Błażejowska, Grzegorz Procyk, Jakub Michał Zimodro, Aleksandra Gąsecka","doi":"10.5603/cj.96477","DOIUrl":"10.5603/cj.96477","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11229805/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141066553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advancements in artificial intelligence-driven techniques for interventional cardiology. 人工智能驱动的介入心脏病学技术的进展。
Cardiology journal Pub Date : 2024-01-01 Epub Date: 2024-01-22 DOI: 10.5603/cj.98650
Zofia Rudnicka, Agnieszka Pręgowska, Kinga Glądys, Mark Perkins, Klaudia Proniewska
{"title":"Advancements in artificial intelligence-driven techniques for interventional cardiology.","authors":"Zofia Rudnicka, Agnieszka Pręgowska, Kinga Glądys, Mark Perkins, Klaudia Proniewska","doi":"10.5603/cj.98650","DOIUrl":"10.5603/cj.98650","url":null,"abstract":"<p><p>This paper aims to thoroughly discuss the impact of artificial intelligence (AI) on clinical practice in interventional cardiology (IC) with special recognition of its most recent advancements. Thus, recent years have been exceptionally abundant in advancements in computational tools, including the development of AI. The application of AI development is currently in its early stages, nevertheless new technologies have proven to be a promising concept, particularly considering IC showing great impact on patient safety, risk stratification and outcomes during the whole therapeutic process. The primary goal is to achieve the integration of multiple cardiac imaging modalities, establish online decision support systems and platforms based on augmented and/or virtual realities, and finally to create automatic medical systems, providing electronic health data on patients. In a simplified way, two main areas of AI utilization in IC may be distinguished, namely, virtual and physical. Consequently, numerous studies have provided data regarding AI utilization in terms of automated interpretation and analysis from various cardiac modalities, including electrocardiogram, echocardiography, angiography, cardiac magnetic resonance imaging, and computed tomography as well as data collected during robotic-assisted percutaneous coronary intervention procedures. Thus, this paper aims to thoroughly discuss the impact of AI on clinical practice in IC with special recognition of its most recent advancements.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11076027/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139514385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hemo-metabolic impairment in patients with ST-segment elevation myocardial infarction: Data from the INTERSTELLAR registry. st段抬高型心肌梗死患者的血液代谢障碍:来自INTERSTELLAR登记的数据。
Cardiology journal Pub Date : 2024-01-01 Epub Date: 2023-11-15 DOI: 10.5603/cj.93926
Min Gyu Kong, Jon Suh, Bora Lee, Hyun Woo Park, Su Yeong Park, Inki Moon, Hyung Oh Choi, Hye-Sun Seo, Yoon Haeng Cho, Nae-Hee Lee, Ho-Jun Jang, Tae-Hoon Kim, Sung Woo Kwon, Sang-Don Park, Pyung Chun Oh, Jeonggeun Moon, Kyounghoon Lee, Woong Chol Kang
{"title":"Hemo-metabolic impairment in patients with ST-segment elevation myocardial infarction: Data from the INTERSTELLAR registry.","authors":"Min Gyu Kong, Jon Suh, Bora Lee, Hyun Woo Park, Su Yeong Park, Inki Moon, Hyung Oh Choi, Hye-Sun Seo, Yoon Haeng Cho, Nae-Hee Lee, Ho-Jun Jang, Tae-Hoon Kim, Sung Woo Kwon, Sang-Don Park, Pyung Chun Oh, Jeonggeun Moon, Kyounghoon Lee, Woong Chol Kang","doi":"10.5603/cj.93926","DOIUrl":"10.5603/cj.93926","url":null,"abstract":"<p><strong>Background: </strong>Not only hemo-dynamic (HD) factors but also hemo-metabolic (HM) risk factors reflecting multi-organ injuries are considered as important prognostic factors in ST-segment elevation myocardial infarction (STEMI). However, studies regarding HM risk factors in STEMI patients are currently limited.</p><p><strong>Method: </strong>Under analysis were 1,524 patients with STEMI who underwent primary percutaneous coronary intervention in the INTERSTELLAR registry. Patients were divided into HM (≥ 2 risk factors) and non-HM impairment groups. The primary outcome was in-hospital all-cause mortality, and the secondary outcome was 1-year all-cause mortality.</p><p><strong>Results: </strong>Of 1,524 patients, 214 (14.0%) and 1,310 (86.0%) patients were in the HM and non-HM impairment groups, respectively. Patients with HM impairment had a higher incidence of in-hospital mortality than those without (24.3% vs. 2.7%, p < 0.001). After adjusting for confounders, HM impairment was independently associated with in-hospital mortality (inverse probability of treatment weighting [IPTW]-adjusted odds ratio: 1.81, 95% confidence interval: 1.08-3.14). In the third door-to-balloon (DTB) time tertile (≥ 82 min), HM impairment was strongly associated with in-hospital mortality. In the first DTB time tertile ( < 62 min), indicating relatively rapid revascularization, HM impairment was consistently associated with increased in-hospital mortality.</p><p><strong>Conclusions: </strong>Hemo-metabolic impairment is significantly associated with increased risk of in-hospital and 1-year mortality in patients with STEMI. It remains a significant prognostic factor, regardless of DTB time.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11229799/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107593127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-term outcomes and quality of life following implementation of dedicated mitral valve Heart Team decisions for patients with severe mitral valve regurgitation in tertiary cardiovascular care center. 在三级心血管护理中心为严重二尖瓣反流患者实施专门的二尖瓣心脏团队决策后的长期结果和生活质量。
Cardiology journal Pub Date : 2024-01-01 Epub Date: 2022-03-14 DOI: 10.5603/CJ.a2022.0011
Szymon Jonik, Michał Marchel, Ewa Pędzich-Placha, Arkadiusz Pietrasik, Adam Rdzanek, Zenon Huczek, Janusz Kochman, Monika Budnik, Radosław Piątkowski, Piotr Scisło, Janusz Kochanowski, Paweł Czub, Radosław Wilimski, Piotr Hendzel, Marcin Grabowski, Krzysztof J Filipiak, Grzegorz Opolski, Tomasz Mazurek
{"title":"Long-term outcomes and quality of life following implementation of dedicated mitral valve Heart Team decisions for patients with severe mitral valve regurgitation in tertiary cardiovascular care center.","authors":"Szymon Jonik, Michał Marchel, Ewa Pędzich-Placha, Arkadiusz Pietrasik, Adam Rdzanek, Zenon Huczek, Janusz Kochman, Monika Budnik, Radosław Piątkowski, Piotr Scisło, Janusz Kochanowski, Paweł Czub, Radosław Wilimski, Piotr Hendzel, Marcin Grabowski, Krzysztof J Filipiak, Grzegorz Opolski, Tomasz Mazurek","doi":"10.5603/CJ.a2022.0011","DOIUrl":"10.5603/CJ.a2022.0011","url":null,"abstract":"<p><strong>Background: </strong>This study was purposed to investigate which treatment strategy was associated with the most favourable prognosis for patients with severe mitral regurgitation (MR) following Heart Team (HT)-decisions implementation.</p><p><strong>Methods: </strong>In this retrospective study, long-term outcomes of patients with severe MR qualified after HT discussion to: optimal medical treatment (OMT) alone, OMT and MitraClip (MC) procedure or OMT and mitral valve replacement (MVR) were evaluated. The primary endpoint was defined as cardiovascular (CV) death and the secondary endpoints included all-cause mortality, myocardial infarctions (MI), strokes, hospitalizations for heart failure exacerbation and CV events during a mean (standard deviation [SD]) follow-up of 29 (15) months.</p><p><strong>Results: </strong>From 2016 to 2019, 176 HT meetings were held and a total of 157 participants (mean age [SD] = 71.0 [9.2], 63.7% male) with severe MR and completely implemented HT decisions (OMT, MC or MVR for 53, 58 and 46 patients, respectively) were included into final analysis. Comparing OMT, MC and MVR groups statistically significant differences between the implemented procedures and occurrence of primary and secondary endpoints with the most frequent in OMT-group were observed (p < 0.05). However, for interventional strategy MC was non-inferior to MVR for all endpoints (p > 0.05). General health status assessed at the end of follow-up were significantly the lowest for MVR, then for MC and the highest for OMT-group (p < 0.01).</p><p><strong>Conclusions: </strong>In the present study it was demonstrated that after careful HT evaluation of patients with severe MR at high risk of surgery, percutaneous strategy (MC) can be considered as equivalent to surgical treatment (MVR) with non-inferior outcomes.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10919556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46370352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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