Cardiology journal最新文献

{"title":"Safety of ultrasound-assisted catheter-directed thrombolysis for central pulmonary embolism in intermediate-high-risk patients with increased bleeding risk in a rural hospital setting.","authors":"Mahmoud Oudeh, Hristo Kirov, Tulio Caldonazo, Angelique Runkel, Wasim Allakkiks, Kai Kögler, Torsten Doenst","doi":"10.5603/cj.103710","DOIUrl":"10.5603/cj.103710","url":null,"abstract":"<p><strong>Background: </strong>The EkoSonic Endovascular System (EKOS™) is an ultrasound-assisted catheter-directed thrombolysis (UACDT) device, which is becoming more popular for treatment of pulmonary embolism (PE) in patients with intermediate-high and high risk. Ultrasound waves help clot fragmentation and dissolution, therefore requiring less thrombolytic agent. With lower doses of thrombolysis, the bleeding risk is reduced but not eliminated. We aimed to evaluate the safety of this therapy in intermediate-high-risk central PE with intermediate and high bleeding risk.</p><p><strong>Methods: </strong>We retrospectively analyzed the database of a rural hospital between March 2021 and July 2024 for UACDT with EKOS™ in patients with intermediate-high-risk central PE and Registro Informatizado de la Enfermedad TromboEmbólica (RIETE) score ≥ 1. We evaluated procedure-related complications, bleeding events within the first 7 days, the need for further intervention, and all-cause in-hospital mortality.</p><p><strong>Results: </strong>Thirty patients underwent UACDT with EKOS™. Their mean age was 68 ± 15.6 years (30% ≥ 80 years). Deep vein thrombosis was present in 16 patients (53.3%). Access was via the brachial vein (23.3%) or the common femoral vein (76.7%). One patient had major bleeding from the access site. There were no other procedure-related major complications. Two patients had minor bleeding events. All bleeding events were managed conservatively without the need for blood transfusion. One patient (3.3%) died in-hospital due to multiple organ failure, and 86% of the patients (26/30) had no complications.</p><p><strong>Conclusions: </strong>Our analysis suggests that UACDT with EKOS™ is safe for the management of intermediate-high-risk central PE in patients with intermediate and high bleeding risk even in a rural hospital setting.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":"33 ","pages":"e00226053"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13189623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147950292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Invest-to-treat drug-coated balloon strategy in chronic total occlusion percutaneous intervention for high-risk stent failure patients.","authors":"Nino Cocco, Agostino Spanò, Claudiu Ungureanu, Giuseppe Colletti, Gregor Leibundgut, Daniel Weilenmann, Giulio Cocco, Simone Calcagno, Giuseppe Biondi-Zoccai, Gian P Ussia, Bernardo Cortese, Kambis Mashayekhi","doi":"10.5603/cj.109595","DOIUrl":"10.5603/cj.109595","url":null,"abstract":"<p><strong>Background: </strong>Long-term patency in complex chronic total occlusion percutaneous intervention (CTO-PCI) is often hindered by a high-risk of stent-failure (HR-SF), impacting prognosis. Drug-coated balloon (DCB) angioplasty may offer an alternative after successful crossing. We evaluated an invest-to-treat DCB strategy, determined by plaque modification results.</p><p><strong>Methods: </strong>Patients with CTO wire-crossing and suboptimal lesion profile for stenting were enrolled at Campus Bio-Medico University Hospital of Rome (April-July 2024). After plaque preparation, results were classified as good, suboptimal, or poor based on residual stenosis and thrombolysis in myocardial infarction (TIMI) flow. Poor results received conventional stenting [drug-eluting stent (DES)]. Good results underwent a nine-month follow-up; suboptimal results underwent a three-month angiography. A \"redo-DCB\" approach was used for persistent suboptimal results within the invest-to-treat strategy.</p><p><strong>Results: </strong>Of 32 CTO-PCIs performed, 29 completed the nine-month follow-up. 11 patients (38%) had poor outflow and required DES (DES-group). The other 18 patients (62%) were managed with DCB alone: six patients (21%) achieved good immediate results (DCB-group), and 12 (41%) were treated as \"DCB-investment\" due to suboptimal plaque modification (DCB-investment group). At the three-month follow-up, four patients (14%) showed improved angiographic results, while six (21%) had suboptimal outcomes and received redo-DCB after plaque modification; two (7%) of these required DES. At nine-months, 14 patients (48%) were successfully treated with a DCB-only approach.</p><p><strong>Conclusions: </strong>This prospective study demonstrates that a DCB strategy for CTO patients with HR-SF is feasible and safe. A DCB-only approach resulted in favorable early outcomes for most patients. In the case of suboptimal initial results, the redo-DCB strategy emerged as a promising alternative to extensive stenting.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":"33 ","pages":"e00226037"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13189593/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147679491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical characteristics of patients with cardiogenic shock after out-of-hospital cardiac arrest (OHCA) compared to patients with cardiogenic shock without OHCA.","authors":"Dominik Krupka, Adam Chełmoński, Karolina Karska, Katarzyna Mazur, Kacper Cicirko, Julia Drewniowska, Kamila Florek, Katarzyna Grunwald, Mateusz Milewski, Michał Nnoli, Jakub Ptak, Mikołaj Błaziak, Bartosz Balcer, Robert Zymliński, Waldemar Goździk, Barbara Barteczko-Grajek, Maciej Bochenek, Roman Przybylski, Michał Zakliczyński, Wiktor Kuliczkowski, Mateusz Sokolski","doi":"10.5603/cj.106691","DOIUrl":"10.5603/cj.106691","url":null,"abstract":"<p><strong>Background: </strong>Cardiogenic shock (CS) often complicates out-of-hospital cardiac arrest (OHCA), contributing to high mortality despite therapeutic advances.</p><p><strong>Methods: </strong>This study retrospectively analysed patients admitted to a tertiary centre between 2021-2024. The cohort of patients with CS was divided into two groups: OHCA with return of spontaneous circulation and non-OHCA.</p><p><strong>Results: </strong>The study included 280 patients with a median age of 69 (60-76) years, of whom 197 (70%) males. There were 46 (16%) patients in the OHCA group and 234 (84%) in non-OHCA. Acute coronary syndrome (ACS) was a more frequent cause of CS in the OHCA group: 36 (78%) vs. 113 (48%), p < 0.01. The OHCA patients were less likely to have hypertension (41% vs. 63%, p < 0.01), chronic heart failure (CHF) (41% vs. 62%, p < 0.01), and a history of percutaneous coronary intervention (11% vs. 29%, p < 0.01). The OHCA patients exhibited lower C-reactive protein) levels and higher levels of white blood cells. Despite distinct profiles, there was no significant difference in mortality between the study groups.</p><p><strong>Conclusions: </strong>Patients with OHCA and non-OHCA CS exhibited distinct clinical profiles, with ACS as the leading cause of OHCA and chronic conditions were more often diagnosed in non-OHCA cases. Similar mortality rates suggest improved OHCA management, emphasizing the need for extensive data collection to assess shock risk.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":"33 ","pages":"e00226045"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13189602/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147792126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stent-assisted coil embolization for a thrombosed giant coronary aneurysm in IgG4-related coronary arteritis: a 2-year follow-up.","authors":"Sang-Suk Choi, Jin Jung, Su Nam Lee, Ki-Dong Yoo, Sung-Ho Her","doi":"10.5603/cj.110587","DOIUrl":"10.5603/cj.110587","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":"33 ","pages":"e00226076"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13666961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149120026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recommendations on the use of a leadless dual-chamber pacemaker.","authors":"Przemysław Mitkowski, Ludmiła Daniłowicz-Szymanowicz, Oskar Kowalski, Marcin Grabowski, Maciej Sterliński, Krzysztof Boczar, Krystian Josiak, Izabela Pieniążek, Jacek Walczak, Maciej Grys, Jarosław Stelmachowski, Grzegorz Mączyński, Piotr Przygodzki, Mateusz Tajstra","doi":"10.5603/cj.109682","DOIUrl":"10.5603/cj.109682","url":null,"abstract":"<p><p>Leadless cardiac pacemakers (LPs) represent a significant advancement in cardiac pacing by eliminating the risks associated with traditional transvenous devices. Although single-chamber LPs have been in clinical use, the recent development of dual-chamber systems, such as AVEIR DR, offers synchronized atrial and ventricular pacing without the complications associated with transvenous hardware. Despite promising results, the widespread clinical adoption of dual-chamber LPs in Poland remains hindered by regulatory and reimbursement challenges. Although patients have access to single-chamber LPs, an unmet clinical need for dual-chamber LPs persists. Addressing this barrier is essential because dual-chamber LPs may optimize treatment by replacing two separate hospitalizations and implantations with a single procedure, thereby reducing the number of interventions and patient risk while lowering healthcare costs. This approach offers both clinical and economic benefits by improving efficiency and resource utilization in the healthcare system. This paper presents national experts' recommendations, supported by clinical research findings, on the use of dual-chamber LPs and solutions to increase their availability to patients in Poland.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":"33 ","pages":"e00226079"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13671391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149186809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rapid and sustained clinical improvement after coronary sinus reducer implantation at the level of the Vieussens valve.","authors":"Tomasz Górnik, Konrad Masiarek, Włodzimierz Grabowicz, Jakub Pitura, Felix Woitek, Michał Plewka","doi":"10.5603/cj.109321","DOIUrl":"10.5603/cj.109321","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":"33 ","pages":"e00226027"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13170446/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147476616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Technologies in minimally invasive treatment of severe mitral regurgitation.","authors":"Magdalena Synak, Marta Mazur, Kamil Marzec, Krzysztof Sanetra, Justyna Jankowska-Sanetra, Piotr P Buszman, Paweł Kaźmierczak, Krzysztof Milewski, Witold Gerber","doi":"10.5603/cj.103296","DOIUrl":"10.5603/cj.103296","url":null,"abstract":"<p><p>Mitral valve regurgitation is the second most common valve defect in Europe among adults. Primary mitral regurgitation (MR) results from structural abnormalities of the valve apparatus (e.g., leaflet prolapse, chordae rupture), often due to myxomatous degeneration or congenital defects. Secondary MR arises from left ventricular remodeling (e.g., after myocardial infarction or heart failure), leading to functional valve incompetence despite normal valve structure. The choice of treatment depends on the degree of valve regurgitation and the severity of the patient's clinical symptoms. The focus herein is on discussing the anatomy of the mitral valve, the pathophysiology of regurgitation, and diagnostic methods. The qualification process is then outlined for invasive treatment and various methods of mitral valve repair, including new minimally invasive techniques. Transcatheter mitral valve repair methods are discussed, among other methods, \"edge-to-edge\" repair and transcatheter mitral valve replacement. Publicly available data confirms that the latter is a widely available and safe treatment method, that represents a promising alternative to surgical treatment.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"e00226001"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13189608/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145679552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of cancer treatments on coronary plaque as assessed by integrated backscatter intravascular ultrasound.","authors":"Yuta Kato, Takashi Kuwano, Makoto Sugihara, Shin-Ichiro Miura","doi":"10.5603/cj.98337","DOIUrl":"10.5603/cj.98337","url":null,"abstract":"<p><strong>Background: </strong>Both cancer itself and cancer treatment [i.e., chemotherapy (CT) and radiotherapy (RT)] are associated with an increased risk of cardiovascular disease. The influence of cancer treatment on the coronary plaque profile was examined as assessed by integrated-backscatter intravascular ultrasound (IB-IVUS).</p><p><strong>Methods: </strong>The patients analyzed were those who had undergone surgery, CT, or RT for cancer prior to undergoing percutaneous coronary intervention (PCI) using IVUS between 2010 and 2020. Grayscale and IB-IVUS analyses were performed for the culprit lesion of a coronary artery just before PCI. To determine the association of cancer treatment with outcomes [% plaque volume index (PVI) and % lipid plaque volume (LV)], we used regression models while adjusting for covariates.</p><p><strong>Results: </strong>A total of 162 chronic coronary syndrome patients who underwent PCI using IVUS were included: 89 received either or both CT and RT ± surgery (CT/RT group), and 73 received surgery alone (surgery group). Compared to the surgery group, the CT/RT group had a high cancer stage, low creatinine and high % LV. By a univariate regression, % PVI was associated with cancer stage (β = -0.16, p = 0.02), RT (β = 0.4, p = 0.02) and HbA1c (β = 0.15, p = 0.01), and % LV was associated with CT/RT (β = 6.93, p = 0.01) and HbA1c (β = 3.65, p = 0.01). After adjustment for covariates, CT/RT was significantly associated with % LV (β = 6.77, p = 0.02), but not with % PVI (β = 0.25, p = 0.15).</p><p><strong>Conclusions: </strong>Chemotherapy and RT were associated with the coronary plaque profile, but not with the coronary plaque volume. Chemotherapy and RT.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"e00226016"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13189618/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145446901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extrapericardic hematoma with bleeding secondary to rib fracture as a cause of Impella CP suction alarm.","authors":"Sarah Mauler-Wittwer, Georgios Giannakopoulos, Marc Arcens, Raphael Giraud, Stephane Noble","doi":"10.5603/cj.107822","DOIUrl":"10.5603/cj.107822","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":"33 ","pages":"e00226019"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13170445/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147286696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of iron deficiency on left ventricular noninvasive myocardial work indices in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation.","authors":"Michał J Błaszkiewicz, Tomasz G Witkowski, Wojciech Bombała, Michał Kosowski, Piotr Kübler, Krzysztof Reczuch, Krzysztof Aleksandrowicz, Ewa A Jankowska, Marcin Protasiewicz","doi":"10.5603/cj.107626","DOIUrl":"10.5603/cj.107626","url":null,"abstract":"<p><strong>Background: </strong>Aortic stenosis (AS) increases left ventricular (LV) afterload and systolic pressure (LVSP). Left ventricular myocardial work (LVMW) enables early detection of LV dysfunction. Recent evidence suggests that ID may reduce LVMW parameters, raising the question of whether ID further impairs LV systolic performance in patients with AS undergoing transcatheter aortic valve implantation (TAVI).</p><p><strong>Methods: </strong>We evaluated 100 patients with severe AS scheduled for TAVI between March 2021 and November 2022. All underwent ID screening according to the classic and novel ID definitions and echocardiographic assessment of LVMW before TAVI and at the 1-year follow-up.</p><p><strong>Results: </strong>Elimination of AS was observed within the 1-year follow-up in the whole population. Despite stable ejection fraction (EF) and global longitudinal strain (GLS), LVMW indices such as global work index (GWI) and global constructive work (GCW) significantly decreased from baseline in the entire population. However, when comparing ID and non-ID patients after the procedure, a statistically significant decrease in GWI and GCW was noted at the 1-year follow-up only in the TSAT > 20% group, not in the TSAT < 20% group. We also noted a significant correlation between TSAT status and echocardiographic as well as LVMW indices. When the classic ID definition was used, all LVMW parameters changed similarly in both groups during follow-up.</p><p><strong>Conclusions: </strong>TAVI significantly influenced the majority of LVMW indices in the overall study population. Using the standard ID definition, ID had no impact on differences in LVMW indices. However, when defined by TSAT < 20%, patients with ID showed no significant post-TAVI changes in LVMW indices.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":"33 ","pages":"e00226049"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13189606/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147847502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}