Cardiology journalPub Date : 2025-01-01Epub Date: 2025-06-03DOI: 10.5603/cj.99047
Amine Al Soueidy, Gregory Miller, Shawana Hussain, Jean-Sebastien Rachoin, Krystal Hunter, Elias Iliadis
{"title":"Aspiration thrombectomy compared to catheter directed thrombolysis in pulmonary embolism: Outcomes from a tertiary referral center.","authors":"Amine Al Soueidy, Gregory Miller, Shawana Hussain, Jean-Sebastien Rachoin, Krystal Hunter, Elias Iliadis","doi":"10.5603/cj.99047","DOIUrl":"10.5603/cj.99047","url":null,"abstract":"<p><strong>Background: </strong>Prompt treatment of pulmonary embolism (PE) prevents morbidity and mortality. The aim of the present study was to evaluate and compare the effectiveness of two FDA-approved catheter-based therapies (CBT) for acute PE: ultrasound-assisted catheter-directed thrombolysis EKOS (EKOS Corporation, Bothell, WA) and Penumbra Indigo aspiration thrombectomy (Penumbra Inc., Alameda, CA, USA).</p><p><strong>Methods: </strong>Patients with submassive and massive PE who underwent CBT between 09/2014 and 08/2022 at our institution were identified. Primary efficacy outcome was change in the echocardiographic RV/LV diameter ratio within 48 to 72h of the procedure.</p><p><strong>Results: </strong>A total of 189 patients underwent EKOS (n=119) or Penumbra (n = 70) for submassive (n = 175) and massive (n = 14) PE. The RV/LV ratio showed improvement post intervention, with 21.2% decrease in the EKOS group (EG) and 35.6% in the Penumbra group (PG). PG group had a greater reduction in RV/LV (median change 0.396 (IQR, 0.347) vs. 0.207 (IQR, 0.306), p < 0.001). The rate of complications and in-hospital mortality were similar (15.1% in EG and 10% in PG and 2.5% in EG, 4.3% in PG, p = 0.672; respectively). Subgroup analysis comparing responders, defined as patients with a post-intervention echocardiographic RV/LV ratio < 0.9, and non-responders showed a lower rate of chronic lung disease, (4.3% vs. 19.0%, p = 0.015).</p><p><strong>Conclusions: </strong>Both CBT options are promising for treating acute submassive or massive PE, with efficacy outcomes favoring aspiration thrombectomy. Presence of chronic lung disease was associated with lower response to CBT in terms of reversal of RV dysfunction. Longer follow-up and randomized controlled trials are needed for definitive conclusions.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"347-356"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12410932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Single left coronary artery to right ventricular fistula with multiple collateral pathways.","authors":"Leizhi Ku, Zheng Liu, Li Zhu, Xiaojing Ma","doi":"10.5603/cj.101474","DOIUrl":"10.5603/cj.101474","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":"32 3","pages":"334-335"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12221322/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiology journalPub Date : 2025-01-01Epub Date: 2025-05-22DOI: 10.5603/cj.102639
Michał Gałeczka, Michał Kapałka, Maciej Chojnicki, Michał Krawiec, Filip Tyc, Roland Fiszer
{"title":"Transcatheter closure of patent ductus arteriosus in infants weighing less than 6 kilograms - a two-center experience. Technical considerations.","authors":"Michał Gałeczka, Michał Kapałka, Maciej Chojnicki, Michał Krawiec, Filip Tyc, Roland Fiszer","doi":"10.5603/cj.102639","DOIUrl":"10.5603/cj.102639","url":null,"abstract":"<p><strong>Background: </strong>Transcatheter closure has become the method of choice for treating patent ductus arteriosus (PDA) in a majority of patients. The only approved device for treating infants weighing less than 6 kilograms is the Amplatzer Piccolo Occluder (APO). The aim of this study is to summarize the experience of two centers in performing transcatheter PDA closure in infants weighing less than 6 kilograms.</p><p><strong>Methods: </strong>Retrospective, descriptive, and nonrandomized analysis included all 45 infants weighing less than 6 kg who underwent transcatheter PDA closure between 2013 and 2023 at two tertiary centers, following the introduction of APO. Medical records, procedural outcomes, and one-month follow-up were analyzed. Applied devices were: APO in 37 (of whom 3 were off-label due to PDA size), Amplatzer Duct Occluder I (ADO) in 3, and Amplatzer Vascular Plug II (AVP) in 5 cases.</p><p><strong>Results: </strong>The overall success rate was 97.8%. There were 2 major complications (4.4%), including one device protrusion. A residual shunt was noted in one patient 24 hours after the procedure, but none were observed after one month. Off-label devices were implanted in insignificantly larger and longer PDAs. There were no significant differences between the labeled and off-label groups in terms of procedural success, major complications, or residual shunts.</p><p><strong>Conclusions: </strong>APO is a safe and effective device to treat PDA in infants weighing less than 6 kilograms, however, off-label devices are needed in a considerable number of patients. Proper use of off-label devices yields comparable to APO results.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"228-233"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12221319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiology journalPub Date : 2025-01-01Epub Date: 2025-05-22DOI: 10.5603/cj.104821
Jacek Kubica, Piotr Adamski, Katarzyna Buszko, Piotr Buszman, Nader Elmasri, Tomasz Fabiszak, Jakub Foryś, Robert Gajda, Mariusz Gąsior, Robert Gil, Paweł Grzelakowski, Tomasz Hajdukiewicz, Miłosz Jaguszewski, Adam Kern, Wacław Kochmann, Jacek Konarski, Aldona Kubica, Tobiasz Kudla, Wiktor Kuliczkowski, Aleksandra Kusińska-Czyczyło, Ewa Laskowska, Przemysław Magielski, Piotr Michalski, Krzysztof Milewski, Natalia Mrzywka, Piotr Niezgoda, Małgorzata Ostrowska, Maciej Piasecki, Przemysław Podhajski, Janusz Prokopczuk, Jakub Ratajczak, Alicja Rzepka-Cholasińska, Grzegorz Skonieczny, Giuseppe Specchia, Łukasz Szarpak, Paweł Szymański, Małgorzata Topolska, Julia M Umińska, Marcin Ziółkowski, Aleksander Żurakowski, Eliano Pio Navarese
{"title":"Extended dual antithrombotic therapy in patients with chronic coronary syndrome - which agent should be added to aspirin?","authors":"Jacek Kubica, Piotr Adamski, Katarzyna Buszko, Piotr Buszman, Nader Elmasri, Tomasz Fabiszak, Jakub Foryś, Robert Gajda, Mariusz Gąsior, Robert Gil, Paweł Grzelakowski, Tomasz Hajdukiewicz, Miłosz Jaguszewski, Adam Kern, Wacław Kochmann, Jacek Konarski, Aldona Kubica, Tobiasz Kudla, Wiktor Kuliczkowski, Aleksandra Kusińska-Czyczyło, Ewa Laskowska, Przemysław Magielski, Piotr Michalski, Krzysztof Milewski, Natalia Mrzywka, Piotr Niezgoda, Małgorzata Ostrowska, Maciej Piasecki, Przemysław Podhajski, Janusz Prokopczuk, Jakub Ratajczak, Alicja Rzepka-Cholasińska, Grzegorz Skonieczny, Giuseppe Specchia, Łukasz Szarpak, Paweł Szymański, Małgorzata Topolska, Julia M Umińska, Marcin Ziółkowski, Aleksander Żurakowski, Eliano Pio Navarese","doi":"10.5603/cj.104821","DOIUrl":"10.5603/cj.104821","url":null,"abstract":"<p><p>According to the 2024ESC Guidelines for the management of chronic coronary syndromes dual antithrombotic treatment comprising aspirin and a second antithrombotic drug for extended long-term prevention should be considered in patients at increased ischemic risk without high bleeding risk. However, no clear indications regarding the choice of a second antithrombotic agent are provided. It was therefore decided to discuss the available evidence regarding this issue. The guidelines provided the number needed to treat (NNT) and the number needed to harm (NNH) for each proposed medication. However, the presented data are misleading and may result in unjustified therapeutic decisions. Due to the great impact of this document on clinical practice all data provided in this document should be carefully verified and commented regarding limitations.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"321-327"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12221334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiology journalPub Date : 2024-01-01Epub Date: 2024-07-08DOI: 10.5603/cj.93499
Xinjian Li, Lin Mi, Juntao Duan, Liyuan Tao, Xinye Xu, Guisong Wang
{"title":"Murray law-based quantitative flow ratio for assessment of nonculprit lesions in patients with ST-segment elevation myocardial infarction.","authors":"Xinjian Li, Lin Mi, Juntao Duan, Liyuan Tao, Xinye Xu, Guisong Wang","doi":"10.5603/cj.93499","DOIUrl":"10.5603/cj.93499","url":null,"abstract":"<p><strong>Introduction: </strong>Revascularization of nonculprit arteries in patients with ST-Segment Elevation Myocardial Infarction (STEMI) is now recommended based on several trials. However, the optimal therapeutic strategy of nonculprit lesions remains unknown. Murray law-based Quantitative Flow Ratio (μQFR) is a novel, non-invasive, vasodilator-free method for evaluating the functional severity of coronary artery stenosis, which has potential applications for nonculprit lesion assessment in STEMI patients.</p><p><strong>Material and methods: </strong>Patients with STEMI who received staged PCI before hospital discharge were enrolled retrospectively. μQFR analyses of nonculprit vessels were performed based on both acute and staged angiography.</p><p><strong>Results: </strong>Eighty-four patients with 110 nonculprit arteries were included. The mean acute μQFR was 0.76 ± 0.18, and the mean staged μQFR was 0.75 ± 0.19. The average period between acute and staged evaluation was 8 days. There was a good correlation (r = 0.719, P < 0.001) between acute μQFR and staged μQFR. The classification agreement was 89.09%. The area under the receiver operator characteristic (ROC) curve for detecting staged μQFR ≤ 0.80 was 0.931.</p><p><strong>Conclusions: </strong>It is feasible to calculate the μQFR during the acute phase of STEMI patients. Acute μQFR and staged μQFR have a good correlation and agreement. The μQFR could be a valuable method for assessing functional significance of nonculprit arteries in STEMI patients.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"522-527"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11374328/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141556140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiology journalPub Date : 2024-01-01Epub Date: 2024-09-17DOI: 10.5603/cj.102158
Grzegorz Gajos
{"title":"SELECT semaglutide to improve outcomes in patients with obesity and cardiovascular disease, also without diabetes.","authors":"Grzegorz Gajos","doi":"10.5603/cj.102158","DOIUrl":"10.5603/cj.102158","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"782-783"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11544414/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142303389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiology journalPub Date : 2024-01-01Epub Date: 2023-12-27DOI: 10.5603/cj.94123
Maciej Dyrbuś, Anna Kurek, Katarzyna Sokoła, Jacek T Niedziela, Mateusz Ostręga, Daniel Cieśla, Mariusz Gąsior, Mateusz Tajstra
{"title":"Low-temperature electrocautery for high-risk cardiac implantable electronic device procedures.","authors":"Maciej Dyrbuś, Anna Kurek, Katarzyna Sokoła, Jacek T Niedziela, Mateusz Ostręga, Daniel Cieśla, Mariusz Gąsior, Mateusz Tajstra","doi":"10.5603/cj.94123","DOIUrl":"10.5603/cj.94123","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"171-173"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10919561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139041043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lipoprotein(a): an important consideration for DAPT therapy after PCI.","authors":"Kongyong Cui, Kefei Dou","doi":"10.5603/cj.98494","DOIUrl":"10.5603/cj.98494","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":"31 2","pages":"365-366"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11076024/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140861298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}