{"title":"Current understanding of Duchenne muscular dystrophy - a purported interview with a purported expert.","authors":"Jarosław Meyer-Szary, Szymon Mikulski","doi":"10.5603/cj.94330","DOIUrl":"10.5603/cj.94330","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":"31 3","pages":"367-368"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11229802/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141473591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiology journalPub Date : 2024-01-01Epub Date: 2024-01-22DOI: 10.5603/cj.96161
Jerzy Sacha, Krzysztof Krawczyk, Przemysław Lipski, Piotr Feusette, Marek Gierlotka
{"title":"Percutaneous transaxillary approach for balloon aortic valvuloplasty and complex percutaneous coronary intervention with Impella support.","authors":"Jerzy Sacha, Krzysztof Krawczyk, Przemysław Lipski, Piotr Feusette, Marek Gierlotka","doi":"10.5603/cj.96161","DOIUrl":"10.5603/cj.96161","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"174-176"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10919560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139514395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiology journalPub Date : 2024-01-01Epub Date: 2023-10-19DOI: 10.5603/cj.97253
Marcin D Drozd, Michał Tkaczyszyn, Monika Kasztura, Kinga Węgrzynowska-Teodorczyk, Irena Flinta, Waldemar Banasiak, Piotr Ponikowski, Ewa A Jankowska
{"title":"Intravenous iron supplementation improves energy metabolism of exercising skeletal muscles without effect on either oxidative stress or inflammation in male patients with heart failure with reduced ejection fraction.","authors":"Marcin D Drozd, Michał Tkaczyszyn, Monika Kasztura, Kinga Węgrzynowska-Teodorczyk, Irena Flinta, Waldemar Banasiak, Piotr Ponikowski, Ewa A Jankowska","doi":"10.5603/cj.97253","DOIUrl":"10.5603/cj.97253","url":null,"abstract":"<p><strong>Background: </strong>Skeletal muscle dysfunction is a feature of heart failure (HF). Iron deficiency (ID) is prevalent in patients with HF associated with exercise intolerance and poor quality of life. Intravenous iron in iron deficient patients with HF has attenuated HF symptoms, however the pathomechanisms remain unclear. The aim of study was to assess whether intravenous iron supplementation as compared to placebo improves energy metabolism of skeletal muscles in patients with HF.</p><p><strong>Methods: </strong>Men with heart failure with reduced ejection fraction (HFrEF) and ID were randomised in 1:1 ratio to either intravenous ferric carboxymaltose (IV FCM) or placebo. In vivo reduction of lactates by exercising skeletal muscles of forearm was analyzed. A change in lactate production between week 0 and 24 was considered as a primary endpoint of the study.</p><p><strong>Results: </strong>There were two study arms: the placebo and the IV FCM (12 and 11 male patients with HFrEF). At baseline, there were no differences between these two study arms. IV FCM therapy as compared to placebo reduced the exertional production of lactates in exercising skeletal muscles. These effects were accompanied by a significant increase in both serum ferritin and transferrin saturation in the IV FCM arm which was not demonstrated in the placebo arm.</p><p><strong>Conclusions: </strong>Intravenous iron supplementation in iron deficient men with HFrEF improves the functioning of skeletal muscles via an improvement in energy metabolism in exercising skeletal muscles, limiting the contribution of anaerobic reactions generating ATP as reflected by a lower in vivo lactate production in exercising muscles in patients with repleted iron stores.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"300-308"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11076021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49686257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiology journalPub Date : 2024-01-01Epub Date: 2024-01-22DOI: 10.5603/cj.95175
Aleksandra Chabior, Agata Tymińska, Agnieszka Pawlak, Andrea Giordani, Alida Caforio, Marcin Grabowski, Krzysztof Ozierański
{"title":"Advances in myocarditis management in the light of the latest research and recent guidelines of the European Society of Cardiology.","authors":"Aleksandra Chabior, Agata Tymińska, Agnieszka Pawlak, Andrea Giordani, Alida Caforio, Marcin Grabowski, Krzysztof Ozierański","doi":"10.5603/cj.95175","DOIUrl":"10.5603/cj.95175","url":null,"abstract":"<p><p>Myocarditis remains an unknown disease with varying clinical manifestations, often leading to heart failure. The latest 2021 and 2022 guidelines of the European Society of Cardiology (ESC) are the first official European documents updating knowledge on the diagnosis and treatment of myocarditis since the 2013 ESC expert consensus statement. These guidelines and new studies allow standardization and improvements to the management of myocarditis. In this review, we discuss the most important aspects of myocarditis diagnosis, therapies and follow-up based on current knowledge.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"342-351"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11076022/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139514388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jacek Klaudel, Wojciech Trenkner, Krzysztof Pawłowski, Piotr Radowski, Dariusz Surman, Bartłomiej Ziniewicz, Michał Smolarczyk, Urszula Kossakowska-Jemioło, Włodzimierz Krasowski
{"title":"Large-bore SOFIA catheter for bailout thrombus aspiration in STEMI.","authors":"Jacek Klaudel, Wojciech Trenkner, Krzysztof Pawłowski, Piotr Radowski, Dariusz Surman, Bartłomiej Ziniewicz, Michał Smolarczyk, Urszula Kossakowska-Jemioło, Włodzimierz Krasowski","doi":"10.5603/cj.95375","DOIUrl":"10.5603/cj.95375","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":"31 2","pages":"352-354"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11076029/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140874372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiology journalPub Date : 2024-01-01Epub Date: 2022-06-15DOI: 10.5603/CJ.a2022.0054
Jarosław Karwowski, Jerzy Rekosz, Renata Mączyńska-Mazuruk, Anna Wiktorska, Karol Wrzosek, Wioletta Loska, Katarzyna Szmarowska, Mateusz Solecki, Joanna Sumińska-Syska, Mirosław Dłużniewski
{"title":"Left atrial appendage thrombus in patients with atrial fibrillation who underwent oral anticoagulation.","authors":"Jarosław Karwowski, Jerzy Rekosz, Renata Mączyńska-Mazuruk, Anna Wiktorska, Karol Wrzosek, Wioletta Loska, Katarzyna Szmarowska, Mateusz Solecki, Joanna Sumińska-Syska, Mirosław Dłużniewski","doi":"10.5603/CJ.a2022.0054","DOIUrl":"10.5603/CJ.a2022.0054","url":null,"abstract":"<p><strong>Background: </strong>Electric cardioversion of atrial fibrillation (AF) is associated with an increased risk of embolism, with embolic material existing in the heart cavities. The initiation of oral anticoagulation therapy reduces the risk of thromboembolic events. The aims of this study were to evaluate the prevalence of left atrial appendage (LAA) thrombi in non-valvular AF, to compare vitamin K antagonists (VKAs) and non-vitamin K oral anticoagulants (NOACs) with respect to thrombus prevalence, and to evaluate the rate of LAA thrombus persistence on repeat transesophageal echocardiography (TEE) after treatment change.</p><p><strong>Methods: </strong>We enrolled 160 consecutive AF patients who presented with an AF duration > 48 h and had undergone TEE before cardioversion.</p><p><strong>Results: </strong>Left atrial appendage thrombus was observed in 12 (7.5%) patients, and spontaneous echo contrast 4 was observed in 19 (11.8%) patients; the incidence was similar between the NOAC and VKA groups (8.9% vs. 3.6% and 12.4% vs. 18.5 %, respectively). Among patients on NOAC, thrombus prevalence was detected in 8.4% of users of rivaroxaban, 8% of users of dabigatran, and 12.5% of users of apixaban.</p><p><strong>Conclusions: </strong>The LAA thrombus developed in 7.5% of patients despite anticoagulation therapy, demonstrating similar prevalence rates among patients either on NOAC or VKA. Lower mean LAA flow velocity and a history of vascular disease were independent predictors of embolic material in the LAA. It seems that in the case of embolic materials in LAA under NOAC treatment, switching to VKA provides additional clinical benefit to the patients.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"461-471"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11229796/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46103594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiology journalPub Date : 2024-01-01Epub Date: 2024-01-22DOI: 10.5603/cj.95152
Krzysztof Brust, Karol Śmiech, Kamil Bujak, Tomasz Roleder, Mariusz Gąsior
{"title":"The characteristic of acute coronary syndromes of patients with multivessel coronary artery disease in centers with and without cardiac surgery on-site.","authors":"Krzysztof Brust, Karol Śmiech, Kamil Bujak, Tomasz Roleder, Mariusz Gąsior","doi":"10.5603/cj.95152","DOIUrl":"10.5603/cj.95152","url":null,"abstract":"<p><strong>Background: </strong>Multivessel disease (MVD) is diagnosed in a fair number of patients with acute coronary syndrome (ACS). There are 36 cardiac-surgery (CS) centres and 157 catheterization laboratories dedicated to treat ACS in Poland. The aim of the study was to analyze MVD patient outcomes presented with ACS in centers with or without CS on-site.</p><p><strong>Methods: </strong>The present study is a retrospective analysis (2017-2020) of MVD ACS patients (n = 4618) outcomes between those treated in centers with CS on site (n = 595) and those without CS (n = 4023).</p><p><strong>Results: </strong>Patients in CS centers had a higher prevalence of renal failure (13.3% vs. 8.8%, p ≤ 0.001) and a more frequent history of coronary angioplasty - percutaneous coronary intervention (18.9% vs. 14.4%, p = 0.005). During the coronary angiography a femoral artery access was more often used in CS center patients (47.1% vs. 15.2%, p < 0.001). Percutaneous coronary intervention of MVD was more often performed in CS centers (74.6% vs. 71.0%, p = 0.054). In-hospital death (7.6% vs. 4.6%, p = 0.002), reinfarction (1.1% vs. 0.1%, p < 0.001), hemorrhagic complications (6.4% vs. 1.6%, p < 0.001), recurrent target vessel revascularization (1.8% vs. 0.4%, p ≤ 0.001) and pulmonary edema (3.7% vs. 1.5%, p < 0.001) occurred more often in CS centers.</p><p><strong>Conclusions: </strong>The safety of ACS treatment in MVD patients in centers without CS on site is non-inferior to their treatment in centers with CS on site. Interestingly, there were more in-hospital adverse events observed in ACS MVD patients treated in centers with CS.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"546-552"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11374331/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139514399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Roman Przybylski, Mikołaj Błaziak, Maciej Bochenek, Anna Jarosz, Barbara Barteczko-Grajek, Michał Zakliczyński, Mateusz Sokolski, Mateusz Garus, Piotr Gajewski, Gracjan Iwanek, Tomasz Skalec, Krzysztof Reczuch, Wiktor Kuliczkowski
{"title":"First use of the Impella 5.5 in a patient with cardiogenic shock to bridge to heart transplantation in Poland.","authors":"Roman Przybylski, Mikołaj Błaziak, Maciej Bochenek, Anna Jarosz, Barbara Barteczko-Grajek, Michał Zakliczyński, Mateusz Sokolski, Mateusz Garus, Piotr Gajewski, Gracjan Iwanek, Tomasz Skalec, Krzysztof Reczuch, Wiktor Kuliczkowski","doi":"10.5603/cj.97518","DOIUrl":"10.5603/cj.97518","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":"31 2","pages":"355-356"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11076034/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140872765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiology journalPub Date : 2024-01-01Epub Date: 2024-08-13DOI: 10.5603/cj.98292
Csaba Földesi, Dejan Kojić, Adriana Sudzinova, Marcin Kuniewicz, Petr Neužil, Zoltan Csanadi, Martin Škamla, Martin Svetlošák, Janusz Romanek, Reece Holbrook, Martin Stefanic, Alicia Sale, Thomas R Holmes, Paweł Ptaszyński
{"title":"Electrophysiology lab efficiency using cryoballoon for pulmonary vein isolation in central and eastern Europe: A sub-analysis of the cryo global registry study.","authors":"Csaba Földesi, Dejan Kojić, Adriana Sudzinova, Marcin Kuniewicz, Petr Neužil, Zoltan Csanadi, Martin Škamla, Martin Svetlošák, Janusz Romanek, Reece Holbrook, Martin Stefanic, Alicia Sale, Thomas R Holmes, Paweł Ptaszyński","doi":"10.5603/cj.98292","DOIUrl":"10.5603/cj.98292","url":null,"abstract":"<p><strong>Background: </strong>Cryoballoon ablation for treatment of atrial fibrillation (AF) reduces procedure times, but limited data is available about its impact on electrophysiology (EP) lab efficiency in Central and Eastern Europe (CEE). Using CEE-specific procedure data, the present study modeled cryoballoon ablation procedures on EP lab resource consumption to improve efficiency.</p><p><strong>Methods: </strong>A discrete event simulation model was developed to assess EP efficiency with cryoballoon ablation. Model inputs were taken from CEE sites within the Cryo Global Registry, namely Czech Republic, Hungary, Poland, Serbia, and Slovakia. The main endpoints were percentage of days that resulted in overtime and percentage of days with time for one extra simple EP procedure. Use of the 'figure of 8' (Fo8) closure technique to reduce procedure time was also examined.</p><p><strong>Results: </strong>The mean lab occupancy time across all CEE sites was 133 ± 47 minutes (min: 104 minutes, max:181 minutes). Cryoballoon ablation in the base-case scenario resulted in 14.6% of days with overtime and 64.8% of days with time for an extra simple EP procedure. Use of the Fo8 closure technique enhanced these values to 5.5% and 85.3%, respectively. Model endpoints were most sensitive to changes in lab occupancy times and overtime start time.</p><p><strong>Conclusions: </strong>In this CEE-specific analysis of EP lab efficiency it was found that 3 cryoballoon ablation procedures could be performed in 1 lab day, leaving time for a 4th simple EP procedure on most days. As such, use cryoballoon ablation for PVI is an effective way to improve EP lab efficiency.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"656-664"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11544417/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141972462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}