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The role of endomyocardial biopsy for surveillance of cardiac allograft rejection: time to move on? 心内膜心肌活检监测同种异体心脏移植排斥反应的作用:是时候继续前进了?
Cardiology journal Pub Date : 2025-01-01 Epub Date: 2025-03-10 DOI: 10.5603/cj.99019
Roberto Gómez-Sánchez, Carlos Ortiz-Bautista, Javier Castrodeza, Zorba Blázquez-Bermejo, Eduardo Zataraín-Nicolás, Adolfo Villa, Ricardo Sanz-Ruiz, Jaime Elízaga, Javier Bermejo
{"title":"The role of endomyocardial biopsy for surveillance of cardiac allograft rejection: time to move on?","authors":"Roberto Gómez-Sánchez, Carlos Ortiz-Bautista, Javier Castrodeza, Zorba Blázquez-Bermejo, Eduardo Zataraín-Nicolás, Adolfo Villa, Ricardo Sanz-Ruiz, Jaime Elízaga, Javier Bermejo","doi":"10.5603/cj.99019","DOIUrl":"10.5603/cj.99019","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"203-205"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12068229/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of dyslipidemia in Poland - common diagnostics, early combined therapy. Expert position statement endorsed by the Polish Cardiac Society Working Group on Cardiovascular Pharmacotherapy. 5th Declaration of Sopot. 波兰血脂异常的治疗-常见诊断,早期联合治疗。波兰心脏病学会心血管药物治疗工作组认可的专家立场声明。索波特第五次宣言。
Cardiology journal Pub Date : 2025-01-01 Epub Date: 2025-03-31 DOI: 10.5603/cj.103680
Marcin Wełnicki, Iwona Gorczyca-Głowacka, Agnieszka Kapłon-Cieślicka, Maciej Janiszewski, Jarosław D Kasprzak, Przemysław Leszek, Anna Tomaszuk-Kazberuk, Maria Łukasiewicz, Mariusz Tomaniak, Stanisław Surma, Agnieszka Mickiewicz, Krzysztof Narkiewicz, Miłosz Jaguszewski, Zbigniew Krasiński, Daniel Śliż, Artur Mamcarz, Filip M Szymański, Marcin Barylski, Beata Wożakowska-Kapłon, Krzysztof J Filipiak
{"title":"Treatment of dyslipidemia in Poland - common diagnostics, early combined therapy. Expert position statement endorsed by the Polish Cardiac Society Working Group on Cardiovascular Pharmacotherapy. 5th Declaration of Sopot.","authors":"Marcin Wełnicki, Iwona Gorczyca-Głowacka, Agnieszka Kapłon-Cieślicka, Maciej Janiszewski, Jarosław D Kasprzak, Przemysław Leszek, Anna Tomaszuk-Kazberuk, Maria Łukasiewicz, Mariusz Tomaniak, Stanisław Surma, Agnieszka Mickiewicz, Krzysztof Narkiewicz, Miłosz Jaguszewski, Zbigniew Krasiński, Daniel Śliż, Artur Mamcarz, Filip M Szymański, Marcin Barylski, Beata Wożakowska-Kapłon, Krzysztof J Filipiak","doi":"10.5603/cj.103680","DOIUrl":"10.5603/cj.103680","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"107-119"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12068240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IVUS-guided cap puncture of a stumpless chronic total occlusion with sliptream technique. 静脉注射引导下滑流技术治疗无残根慢性全闭塞的帽穿刺。
Cardiology journal Pub Date : 2025-01-01 DOI: 10.5603/cj.99193
Mohsen Mohandes, Cristina Moreno, Luis Mauricio Torres, Humberto Coimbra, José Luis Ferreiro
{"title":"IVUS-guided cap puncture of a stumpless chronic total occlusion with sliptream technique.","authors":"Mohsen Mohandes, Cristina Moreno, Luis Mauricio Torres, Humberto Coimbra, José Luis Ferreiro","doi":"10.5603/cj.99193","DOIUrl":"10.5603/cj.99193","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":"32 1","pages":"104-105"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11870012/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143517680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Utility of contrast-enhanced echocardiography in the diagnosis of left ventricular aneurysm. 超声心动图造影在左心室动脉瘤诊断中的应用。
Cardiology journal Pub Date : 2025-01-01 DOI: 10.5603/cj.101044
Jing Ma, Mingxing Xie, Yali Yang, Yuman Li
{"title":"Utility of contrast-enhanced echocardiography in the diagnosis of left ventricular aneurysm.","authors":"Jing Ma, Mingxing Xie, Yali Yang, Yuman Li","doi":"10.5603/cj.101044","DOIUrl":"10.5603/cj.101044","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":"32 4","pages":"438-439"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12410938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144982378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Validation of the COAPT risk score in Polish patients undergoing transcatheter edge-to-edge repair of severe, functional mitral regurgitation: a multicenter, observational study. 波兰接受经导管边缘到边缘修复严重功能性二尖瓣反流患者COAPT风险评分的验证:一项多中心观察性研究
Cardiology journal Pub Date : 2025-01-01 DOI: 10.5603/cj.100877
Karolina Jasińska-Gniadzik, Michał Łomiak, Jerzy Pręgowski, Zbigniew Chmielak, Piotr Kasprzyk, Jan Kasprzyk, Rafał Gałąska, Michał Chmielecki, Miłosz J Jaguszewski, Marcin Fijałkowski, Aleksandra Topolska, Michał Sekuła, Marcin Grabowski, Janusz Kochman, Adam Rdzanek, Piotr Scislo, Agnieszka Kapłon-Cieślicka, Renata Główczyńska, Monika Budnik, Radosław Piątkowski, Łukasz Kołtowski, Arkadiusz Pietrasik, Aleksandra Gąsecka
{"title":"Validation of the COAPT risk score in Polish patients undergoing transcatheter edge-to-edge repair of severe, functional mitral regurgitation: a multicenter, observational study.","authors":"Karolina Jasińska-Gniadzik, Michał Łomiak, Jerzy Pręgowski, Zbigniew Chmielak, Piotr Kasprzyk, Jan Kasprzyk, Rafał Gałąska, Michał Chmielecki, Miłosz J Jaguszewski, Marcin Fijałkowski, Aleksandra Topolska, Michał Sekuła, Marcin Grabowski, Janusz Kochman, Adam Rdzanek, Piotr Scislo, Agnieszka Kapłon-Cieślicka, Renata Główczyńska, Monika Budnik, Radosław Piątkowski, Łukasz Kołtowski, Arkadiusz Pietrasik, Aleksandra Gąsecka","doi":"10.5603/cj.100877","DOIUrl":"10.5603/cj.100877","url":null,"abstract":"<p><strong>Background: </strong>The COAPT risk score, developed based on the COAPT trial, is a tool to predict the risk of death or hospitalization for heart failure (HFH) within two years after transcatheter edge-to-edge repair (TEER) of mitral regurgitation using a MitraClip device. We aimed to validate the Score in a Polish population.</p><p><strong>Methods: </strong>Patients with severe mitral regurgitation who underwent TEER with MitraClip at three cardiology centers in Poland between November 2015 and February 2023 were included. Patients were divided into two groups based on the COAPT trail criteria: COAPT eligible and COAPT non-eligible. Clinical data were collected from medical records and the COAPT risk score was calculated for each patient. Outcomes were collected during the two-year follow-up period. The primary endpoint was a composite of all-cause mortality and HFH at two-year follow-up and evaluated in the overall cohort and separately for COAPT-eligible and -non-eligible patients.</p><p><strong>Results: </strong>A total of 225 patients were included in the study: 134 COAPT eligible (60%) and 91 COAPT non-eligible (40%). Higher COAPT risk score was associated with increased risk of primary endpoint in the overall population and in COAPT-eligible patients. The score demonstrated moderate discrimination (area under curve [AUC] = 0.581) and poor calibration (Hosmer-Lemeshow [HL] p = 0.085) in the overall population, whereas it showed moderate discrimination (AUC = 0.600) and good calibration (HL p = 0.308) in COAPT-eligible patients.</p><p><strong>Conclusions: </strong>In Polish patients fulfilling COAPT criteria, the COAPT risk score has moderate predictive value for post-procedural outcomes. In COAPT non-eligible patients, novel tools are required to predict outcomes.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":"32 3","pages":"258-269"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12221333/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Single-stage pulmonary vein isolation combined with percutaneous implantation of left atrial appendage occluder in patients with recent onset ischemic stroke and atrial fibrillation (PILOS-AF): A study protocol of randomized controlled trial. 单期肺静脉隔离联合经皮左房附件封堵器治疗初发缺血性卒中合并心房颤动(PILOS-AF):一项随机对照试验研究方案
Cardiology journal Pub Date : 2025-01-01 Epub Date: 2025-06-03 DOI: 10.5603/cj.104167
Maciej T Wybraniec, Andrzej Hoffmann, Tomasz Bochenek, Michał Lelek, Marcin Wita, Krzysztof Szydło, Anetta Lasek-Bal, Mariusz Gąsior, Zbigniew Kalarus, Paweł Ptaszyński, Jarosław Kaźmierczak, Katarzyna Mizia-Stec, Krystian Wita
{"title":"Single-stage pulmonary vein isolation combined with percutaneous implantation of left atrial appendage occluder in patients with recent onset ischemic stroke and atrial fibrillation (PILOS-AF): A study protocol of randomized controlled trial.","authors":"Maciej T Wybraniec, Andrzej Hoffmann, Tomasz Bochenek, Michał Lelek, Marcin Wita, Krzysztof Szydło, Anetta Lasek-Bal, Mariusz Gąsior, Zbigniew Kalarus, Paweł Ptaszyński, Jarosław Kaźmierczak, Katarzyna Mizia-Stec, Krystian Wita","doi":"10.5603/cj.104167","DOIUrl":"10.5603/cj.104167","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"416-424"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12410937/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differences in coronary microcirculation measurements during regadenoson vs. adenosine - induced hyperemia. regadenoson与adenoine诱导的充血期间冠状动脉微循环测量的差异。
Cardiology journal Pub Date : 2025-01-01 Epub Date: 2024-12-20 DOI: 10.5603/cj.97857
Rafał Januszek, Wojciech Siłka, Natalia Bukała, Michał Chyrchel, Wojciech Wańha, Andrzej Surdacki, Stanisław Bartuś
{"title":"Differences in coronary microcirculation measurements during regadenoson vs. adenosine - induced hyperemia.","authors":"Rafał Januszek, Wojciech Siłka, Natalia Bukała, Michał Chyrchel, Wojciech Wańha, Andrzej Surdacki, Stanisław Bartuś","doi":"10.5603/cj.97857","DOIUrl":"10.5603/cj.97857","url":null,"abstract":"<p><strong>Background: </strong>Little is known about the similarity of microcirculation assessment outcomes performed with regadenoson and adenosine. The aim of the current study was to compare coronary flow reserve (CFR) and index of microcirculatory resistance (IMR) assessment using adenosine and regadenoson, and to evaluate predictors regarding the size of differences.</p><p><strong>Methods: </strong>44 patients were enrolled and diagnosed between 2021 and 2023. Fractional flow reserve (FFR), CFR and IMR were measured twice in the circumflex (Cx) (n = 8) or left anterior descending (LAD) (n = 36) artery: once with continuous infusion of adenosine (Adenocor 140 µg/kg/min) and 10 minutes later with regadenoson (Rapiscan 400 µg i.v.).</p><p><strong>Results: </strong>Averaged results were quantified with adenosine and regadenoson for FFR (0.81 [0.75 ÷ 0.89] vs. 0.80 [0.73 ÷ 0.88]), CFR (3.84 [1.67 ÷ 4.08] vs. 3.97 [1.78 ÷ 4.32]) and IMR (20.01 [11 ÷ 24.5] vs. 20.25 [10.75 ÷ 23]), respectively. None of the differences were statistically significant. Among the significant (p < 0.05) predictors of greater ΔCFR, the following can be noted: prior percutaneous transluminal angioplasty/carotid artery stenting (β = 2.35), oral anticoagulant usage (β = 0.89), and prior stroke/transient ischaemic attack (TIA) (β = 1.09), with the latter being also confirmed for greater ΔIMR (β = 8.89). Moreover, patients with New York Heart Association (NYHA) class II/III, as compared to those with NYHA class I, were more likely to have greater ΔIMR (β = 11.89).</p><p><strong>Conclusions: </strong>Regadenoson may be a feasible alternative to adenosine in coronary microcirculation assessment, as it produces similar outcomes. Selected factors were found to be predictors of greater differences in IMR, CFR and FFR values according to the agent used for coronary hyperemia.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"19-25"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11870001/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Air embolism resulting from atrioesophageal fistula following thoracoscopic atrial fibrillation ablation. 胸腔镜房颤消融后心房食管瘘所致空气栓塞。
Cardiology journal Pub Date : 2025-01-01 DOI: 10.5603/cj.98108
Fangxiao Gong, Sen Ye
{"title":"Air embolism resulting from atrioesophageal fistula following thoracoscopic atrial fibrillation ablation.","authors":"Fangxiao Gong, Sen Ye","doi":"10.5603/cj.98108","DOIUrl":"10.5603/cj.98108","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":"32 1","pages":"100-101"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11870007/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143517661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preventing chronic heart failure and improving survival after transcatheter aortic valve implantation in patients with the need for permanent pacemaker implantation: Rationale and design of the physiologic cardiac pacing to prevent left ventricular dysfunction post transcatheter aortic valve implantation (PACE-4-TAVI) trial. 预防经导管主动脉瓣植入术后慢性心力衰竭,提高需要永久起搏器植入术患者的生存率:经导管主动脉瓣植入术后生理性心脏起搏预防左心室功能障碍的原理和设计(PACE-4-TAVI)试验
Cardiology journal Pub Date : 2025-01-01 Epub Date: 2025-03-20 DOI: 10.5603/cj.100726
Danuta Łoboda, Rafał Gardas, Tomasz Soral, Radosław Gocoł, Damian Hudziak, Dariusz Jagielski, Jerzy K Wranicz, Jarosław Kaźmierczak, Jacek Lelakowski, Przemysław Mitkowski, Grzegorz Smolka, Wojciech Wojakowski, Krzysztof S Gołba
{"title":"Preventing chronic heart failure and improving survival after transcatheter aortic valve implantation in patients with the need for permanent pacemaker implantation: Rationale and design of the physiologic cardiac pacing to prevent left ventricular dysfunction post transcatheter aortic valve implantation (PACE-4-TAVI) trial.","authors":"Danuta Łoboda, Rafał Gardas, Tomasz Soral, Radosław Gocoł, Damian Hudziak, Dariusz Jagielski, Jerzy K Wranicz, Jarosław Kaźmierczak, Jacek Lelakowski, Przemysław Mitkowski, Grzegorz Smolka, Wojciech Wojakowski, Krzysztof S Gołba","doi":"10.5603/cj.100726","DOIUrl":"10.5603/cj.100726","url":null,"abstract":"","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"195-202"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12068226/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The utility of brain biomarkers in predicting survival and neurological outcomes in pediatric patients after cardiac arrest: A systematic review and meta-analysis. 脑生物标志物在预测心脏骤停后儿科患者生存和神经预后方面的应用:一项系统综述和荟萃分析。
Cardiology journal Pub Date : 2025-01-01 Epub Date: 2025-03-10 DOI: 10.5603/cj.103883
Halla Kamińska, Krzysztof Kurek, Michał Zembala, Sagar Galwankar, Monika Tomaszewska, Shraddha Singh, Nicola Luigi Bragazzi, Michał Pruc, Basar Cander, Francesco Chirico, Amelia Rizzo, Jacek Kubica, Ayman El-Menyar, Anne Lepetit, Pawel Patrzylas, Zubaid Rafique, W Frank Peacock, Łukasz Szarpak
{"title":"The utility of brain biomarkers in predicting survival and neurological outcomes in pediatric patients after cardiac arrest: A systematic review and meta-analysis.","authors":"Halla Kamińska, Krzysztof Kurek, Michał Zembala, Sagar Galwankar, Monika Tomaszewska, Shraddha Singh, Nicola Luigi Bragazzi, Michał Pruc, Basar Cander, Francesco Chirico, Amelia Rizzo, Jacek Kubica, Ayman El-Menyar, Anne Lepetit, Pawel Patrzylas, Zubaid Rafique, W Frank Peacock, Łukasz Szarpak","doi":"10.5603/cj.103883","DOIUrl":"10.5603/cj.103883","url":null,"abstract":"<p><strong>Background: </strong>Cardiac arrest in children is associated with high morbidity and mortality, primarily due to neurological injury. Biomarkers linked to brain injury, released into circulation from compromised elements of the neurovascular unit, act as significant prognostic indicators in patients suffering from hypoxic-ischemic brain injury (HIBI) subsequent to the restoration of spontaneous circulation (ROSC) after pediatric cardiac arrest. The aim of this systematic review and meta-analysis is to evaluate the prognostic utility of brain injury biomarkers in predicting neurological outcomes and survival in patients following cardiac arrest in the pediatric population.</p><p><strong>Methods: </strong>Bibliographic databases (PubMed, the Cochrane Library, and Embase) were searched from their inception to November 2024. A random-effect model was used for all analyses.</p><p><strong>Results: </strong>Our meta-analysis demonstrates significant associations between various biomarkers and survival or neurological outcomes after cardiac arrest. Neuron-specific enolase (NSE) levels were consistently elevated in non-survivors and patients with unfavorable neurological outcomes, with pronounced differences observed on Days 2 and 3 (e.g., Day 3 mean difference: -88.48, 95%CI: -146.77 to -30.19, P = 0.003). Emerging biomarkers, including UCH-L1 and GFAP, showed striking differences, such as elevated UCH-L1 levels on Day 1 (mean difference: -415.41, 95%CI: -474.41 to -356.61, P < 0.001) and GFAP levels exceeding 4000 ng/mL in non-survivors on Day 2 (P < 0.001).</p><p><strong>Conclusions: </strong>Our findings underscore the significant prognostic value of biomarkers in predicting survival and neurological outcomes following cardiac arrest. Neuron-specific enolase (NSE) consistently demonstrated its reliability across multiple time points, while emerging biomarkers like UCH-L1 and GFAP showed promising potential for early outcome stratification.</p>","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"130-141"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12068238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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