Cardiology journal最新文献_第8页

Evolution of transcatheter interventions for secondary atrioventricular valve regurgitation: how to set up an edge-to-edge structural program. 经导管介入治疗继发性房室瓣反流的发展：如何建立从边缘到边缘的结构方案。

Cardiology journal Pub Date : 2024-01-01 Epub Date: 2024-07-17 DOI: 10.5603/cj.96738

Alexandru Ionut Patrascu, Donat Binder, Ibrahim Alashkar, Amr Mady, Peter Schnabel, Wilfried Staehle, Kai Weinmann, Osama Risha, Ilka Ott

引用次数: 0

Should dual antiplatelet treatment be guided by lipoprotein(a) concentration? 双联抗血小板治疗是否应以脂蛋白（a）浓度为指导？

Cardiology journal Pub Date : 2024-01-01 DOI: 10.5603/cj.97979

Jacek Kubica

引用次数: 0

Study design and rationale of the angio-based final functional effect of PCI (AFFE PCI) study: a prospective multi-center study of post-PCI vFFR impact on clinical outcomes and residual angina. 基于血管造影的 PCI 最终功能效应（AFFE PCI）研究的研究设计和原理：PCI 后 vFFR 对临床结果和残余心绞痛影响的前瞻性多中心研究。

Cardiology journal Pub Date : 2024-01-01 Epub Date: 2024-05-02 DOI: 10.5603/cj.99332

Mariusz Tomaniak, Karol Sadowski, Adrian Bednarek, Zenon Huczek, Marek Gierlotka, Michał Hawranek, Marcin Grabowski, Wojciech Wojakowski, Krzysztof Milewski, Janusz Kochman

引用次数: 0

Effect of diabetes mellitus on 3-year outcomes in patients with acute myocardial infarction with nonobstructive coronary arteries. 糖尿病对冠状动脉非阻塞性急性心肌梗死患者 3 年预后的影响。

Cardiology journal Pub Date : 2024-01-01 Epub Date: 2024-08-08 DOI: 10.5603/cj.97842

Yong Hoon Kim, Ae-Young Her, Seung-Woon Rha, Cheol Ung Choi, Byoung Geol Choi, Soohyung Park, Dong Oh Kang, Su Jin Hyun, Jung Rae Cho, Ji Young Park, Sang-Ho Park, Myung Ho Jeong

{"title":"Effect of diabetes mellitus on 3-year outcomes in patients with acute myocardial infarction with nonobstructive coronary arteries.","authors":"Yong Hoon Kim, Ae-Young Her, Seung-Woon Rha, Cheol Ung Choi, Byoung Geol Choi, Soohyung Park, Dong Oh Kang, Su Jin Hyun, Jung Rae Cho, Ji Young Park, Sang-Ho Park, Myung Ho Jeong","doi":"10.5603/cj.97842","DOIUrl":"10.5603/cj.97842","url":null,"abstract":"Background: Diabetes mellitus (DM) is a significant factor in increased mortality rates among patients with acute myocardial infarction (AMI), but research on its impact on the long-term outcomes in patients with MI with nonobstructive coronary arteries (MINOCA) is limited. Thus, a comparison of the 3-year clinical outcomes between the DM and non-DM groups among patients with MINOCA was undertaken.Methods: From the Korea AMI Registry-National Institute of Health dataset, 10,774 AMI patients were enrolled. After applying the exclusion criteria, 379 patients with MINOCA were included. The primary clinical outcomes were major adverse cardiac and cerebrovascular events (MACCE), defined as all-cause death, recurrent myocardial infarction (MI), repeat coronary revascularization, and stroke. The secondary outcomes were the individual components of MACCE.Results: The adjusted hazard ratios for 3-year MACCE (2.287, p = 0.010), all-cause death (2.845, p = 0.004), and non-cardiac death (non-CD, 3.914, p = 0.008) were higher in the DM group than in the non-DM group. It is speculated that the higher non-CD rate in the MINOCA group is attributable to a higher proportion of patients with non-ST-segment elevation MI in the total study population. The CD, recurrent MI, revascularization, and stroke rates were similar between the DM and non-DM groups. DM, advanced age, cardiopulmonary resuscitation on admission, and non-use of statin medications were significant predictors of MACCE.Conclusions: In this study involving patients with MINOCA, the DM group exhibited a higher 3-year mortality rate than the non-DM group. Thus, DM demonstrated a hazardous effect even in patients with MINOCA.","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11544401/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141903963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Laser for a complex PCI with ISR, undilatable, and uncrossable lesions. 激光用于具有 ISR、无法扩张和无法穿越病变的复杂 PCI。

Cardiology journal Pub Date : 2024-01-01 DOI: 10.5603/cj.92915

Zhongxiu Chen, Yong Chen, Minggang Zhou, Yong He

引用次数: 0

Association between cognitive impairment and risk of atrial fibrillation: The Atherosclerosis Risk in Communities study. 认知障碍与心房颤动风险之间的关系：社区动脉粥样硬化风险研究。

Cardiology journal Pub Date : 2024-01-01 Epub Date: 2023-10-19 DOI: 10.5603/cj.93107

Yizhou Li, Yu Jia, Wenli Jiang, Dongze Li, Jing Yu, Yi Liu, Xiaoyang Liao, Zhiwei Zhao

{"title":"Association between cognitive impairment and risk of atrial fibrillation: The Atherosclerosis Risk in Communities study.","authors":"Yizhou Li, Yu Jia, Wenli Jiang, Dongze Li, Jing Yu, Yi Liu, Xiaoyang Liao, Zhiwei Zhao","doi":"10.5603/cj.93107","DOIUrl":"10.5603/cj.93107","url":null,"abstract":"Background: Atrial fibrillation (AF) is reportedly a risk factor for cognitive impairment. Interestingly, recent studies have emphasized that impaired cognition is probably an initiating factor of cardiovascular disease. Thus, we aimed to explore the association between impaired cognition and the risk of AF, and clarify the potential mechanisms.Methods: Participants of visit 2 (1991-1993) in the Atherosclerosis Risk in Communities study were included. Global cognition z-scores and factor scores were calculated using the word fluency, delayed word recall, and digit symbol substitution tests. AF incidents were diagnosed by electrocardiography and inpatient records. The association of cognitive decline with AF risk and left atrial volume index (LAVI) was explored using Cox proportional hazards and linear regression models, respectively.Results: During the median follow-up of 18.2 ± 6.2 years, 2056/11,675 (17.6%) participants developed AF. Participants in the lowest quartile of global cognition z- and factor scores had a higher risk of AF (hazard ratio [HR]: 1.271, 95% confidence interval [CI]: 1.094-1.477, p = 0.002; HR: 1.305, 95% CI: 1.110-1.535, p = 0.001, respectively) than those in the highest quartile. Global cognition z- and factor scores were negatively correlated with the LAVI (B: -0.411, 95% CI: -0.749 to -0.074, p = 0.017; B: -0.425, 95% CI: -0.833 to -0.017, p = 0.041, respectively).Conclusions: Cognitive decline is significantly associated with a higher risk of AF, with atrial remodeling being a potential mechanism. Our results extend previous findings of the brain-heart axis and indicate the effects of cognitive injury on cardiac function and structure.Registration: URL: https://www.Clinicaltrials: gov; unique identifier: NCT00005131.","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11374324/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49686333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cangrelor - Expanding therapeutic options in patients with acute coronary syndrome. angrelor -扩大急性冠脉综合征患者的治疗选择。

Cardiology journal Pub Date : 2024-01-01 Epub Date: 2023-11-15 DOI: 10.5603/cj.96076

Jacek Kubica, Piotr Adamski, Sławomir Dobrzycki, Robert Gajda, Mariusz Gąsior, Marek Gierlotka, Miłosz Jaguszewski, Jacek Legutko, Maciej Lesiak, Eliano P Navarese, Piotr Niezgoda, Małgorzata Ostrowska, Tomasz Pawłowski, Agnieszka Tycińska, Julia M Umińska, Adam Witkowski, Robert Gil

{"title":"Cangrelor - Expanding therapeutic options in patients with acute coronary syndrome.","authors":"Jacek Kubica, Piotr Adamski, Sławomir Dobrzycki, Robert Gajda, Mariusz Gąsior, Marek Gierlotka, Miłosz Jaguszewski, Jacek Legutko, Maciej Lesiak, Eliano P Navarese, Piotr Niezgoda, Małgorzata Ostrowska, Tomasz Pawłowski, Agnieszka Tycińska, Julia M Umińska, Adam Witkowski, Robert Gil","doi":"10.5603/cj.96076","DOIUrl":"10.5603/cj.96076","url":null,"abstract":"Cangrelor is the only intravenous P2Y12 receptor antagonist. It is an adenosine triphosphate analog that selectively, directly, and reversibly binds to the platelet P2Y12 receptors exerting its antiaggregatory effect. Cangrelor is characterized by linear, dose-dependent pharmacokinetics and rapid onset of action providing potent platelet inhibition exceeding 90%. Cangrelor is rapidly metabolized by endothelial endonucleotidase; thus, its half-life is 2.9 to 5.5 min, and its antiplatelet effect subsides within 60 to 90 min. Data originating from three pivotal cangrelor trials (CHAMPION PLATFORM, CHAMPION PCI, and CHAMPION PHOENIX) indicate that cangrelor reduces the risk of periprocedural thrombotic complications during percutaneous coronary intervention at the expense of mild bleedings. Its unique pharmacological properties allow it to overcome the limitations of oral P2Y12 receptor inhibitors, mainly related to the delayed and decreased bioavailability and antiplatelet effect of these agents, which are often observed in the setting of acute coronary syndrome. Subgroups of patients who could theoretically benefit the most from cangrelor include those in whom pharmacokinetics and pharmacodynamics of oral P2Y12 receptor antagonists are most disturbed, namely patients with ST-segment elevation myocardial infarction, those treated with opioids, with mild therapeutic hypothermia, or in cardiogenic shock. Cangrelor could also be useful if bridging is required in patients undergoing surgery. According to the current guidelines cangrelor may be considered in P2Y12 receptor inhibitor-naïve patients undergoing percutaneous coronary intervention in both acute and stable settings.","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10919555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107593125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Coronary laser with simultaneous contrast injection for the treatment of stent underexpansion. 冠状动脉激光同时注射造影剂治疗支架扩张不足。

Cardiology journal Pub Date : 2024-01-01 Epub Date: 2023-10-19 DOI: 10.5603/cj.96438

Mohsen Mohandes, Alberto Pernigotti, Cristina Moreno, Luis Mauricio Torres, Francisco Fernández, Diego Zambrano, Alfredo Bardají

{"title":"Coronary laser with simultaneous contrast injection for the treatment of stent underexpansion.","authors":"Mohsen Mohandes, Alberto Pernigotti, Cristina Moreno, Luis Mauricio Torres, Francisco Fernández, Diego Zambrano, Alfredo Bardají","doi":"10.5603/cj.96438","DOIUrl":"10.5603/cj.96438","url":null,"abstract":"Background: Stent underexpansion is a challenge in interventional cardiology. Some off-label treatments, such as rotational atherectomy, intravascular lithotripsy (IVL) and coronary lasing, have been used to overcome the problem. The purpose of this study is to evaluate the safety and efficacy of coronary laser atherectomy with simultaneous contrast injection and subsequent balloon dilation to optimize stent expansion.Methods: Coronary laser atherectomy with simultaneous contrast injection was used. After lasing, non-compliant balloon dilation at high pressure was performed to overcome the underexpanded point. The average increase in the minimum stent area (MSA) was measured by intravascular ultrasound (IVUS), and any complication related to the technique was evaluated. Additionally, major adverse cardiovascular events (MACE), consisting of death from any cause, new myocardial infarction (MI) and target lesion revascularization (TLR), were scrutinized in a long-term follow-up.Results: Sixteen underexpanded stents were treated with laser between August 2017 and November 2022. In all cases but one, IVUS was used to evaluate the MSA before and after lasing. The MSA showed an average increase of 2.34 ± 1.57 mm² (95% confidence interval [CI]: 1.47-3.21; p < 0.001) after laser application and balloon inflation. No complication related to the technique was detected. During a follow-up period of a median (interquartile range) of 457 (50-973) days, the combined MACE assessed by Kaplan-Meier estimator showed an event-free rate of 0.82 (95% CI: 0.59-1).Conclusions: Coronary laser with simultaneous contrast injection is a safe method to optimize a stent underexpansion, with an acceptable event-free rate in long-term follow-up.","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11076023/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49686334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical characteristics and predictors of in-hospital mortality of patients hospitalized with myocardial infarction before and during COVID-19 pandemic. 在 COVID-19 大流行之前和期间住院的心肌梗死患者的临床特征和院内死亡率预测因素。

Cardiology journal Pub Date : 2024-01-01 Epub Date: 2024-06-04 DOI: 10.5603/cj.95392

Adam Kern, Sebastian Pawlak, Grzegorz Poskrobko, Krystian Bojko, Leszek Gromadziński, Dariusz Onichimowski, Rakesh Jalali, Ewa Andrasz, Jacek Bil

{"title":"Clinical characteristics and predictors of in-hospital mortality of patients hospitalized with myocardial infarction before and during COVID-19 pandemic.","authors":"Adam Kern, Sebastian Pawlak, Grzegorz Poskrobko, Krystian Bojko, Leszek Gromadziński, Dariusz Onichimowski, Rakesh Jalali, Ewa Andrasz, Jacek Bil","doi":"10.5603/cj.95392","DOIUrl":"10.5603/cj.95392","url":null,"abstract":"Background: The COVID-19 pandemic has impacted many acute coronary syndrome (ACS) care aspects. The aim was to compare the patient profile, ACS characteristics, and the outcomes in patients referred to the invasive cardiology department before (March 2019 - February 2020) and during the COVID-19 pandemic (March 2020 - February 2021).Methods: Clinical and demographic features, comorbidities, laboratory parameters at admission, and periprocedural data were recorded. The relationship of these parameters with in-hospital mortality was assessed.Results: Before the COVID-19 pandemic, 664 patients were admitted due to ACS (mean age 67.16 ± 11.94 years, females 32.1%), and during the COVID-19 pandemic 545 ACS patients were recorded [mean age 66.02 ± 12.02 years (p = 0.463), females 31% (p = 0.706)]. A 17.8% decrease in the ACS rate was observed. During the pandemic, there were more STEMI patients (44.3% vs. 52.1%, p < 0.001) and fewer patients treated conservatively (24.9% vs. 8%, p < 0.001). Most lesions were located in the left anterior descending artery (53.4% vs. 54.7%), but post-percutaneous coronary intervention TIMI 3 was observed more frequently before the pandemic (83.9% vs. 75.1%, p < 0.001). Periprocedural complication rates did not differ between the groups. In-hospital outcomes did not differ between analyzed periods regarding all-cause death nor cardiac death rates, 5.3% vs. 4.6% (p = 0.598) and 4.5% vs. 3.7% (p = 0.473), respectively.Conclusions: Based on the analysis of 1209 patients, a decrease in ACS patients admitted during the pandemic was recorded, but in-hospital mortality remained similar.","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11544407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141237669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predictive value of early left ventricular end-diastolic volume changes for late left ventricular remodeling after ST-elevation myocardial infarction. ST段抬高型心肌梗死后早期左心室舒张末期容积变化对晚期左心室重构的预测价值。

Cardiology journal Pub Date : 2024-01-01 Epub Date: 2023-09-29 DOI: 10.5603/cj.90492

Lei Yi, Tianqi Zhu, Xuezheng Qu, Keremu Buayiximu, Shuo Feng, Zhengbin Zhu, Jingwei Ni, Run Du, Jingzhou Zhu, Xiaoqun Wang, Fenghua Ding, Ruiyan Zhang, Weiwei Quan, Xiaoxiang Yan

{"title":"Predictive value of early left ventricular end-diastolic volume changes for late left ventricular remodeling after ST-elevation myocardial infarction.","authors":"Lei Yi, Tianqi Zhu, Xuezheng Qu, Keremu Buayiximu, Shuo Feng, Zhengbin Zhu, Jingwei Ni, Run Du, Jingzhou Zhu, Xiaoqun Wang, Fenghua Ding, Ruiyan Zhang, Weiwei Quan, Xiaoxiang Yan","doi":"10.5603/cj.90492","DOIUrl":"10.5603/cj.90492","url":null,"abstract":"Backgroud: Left ventricular remodeling (LVR) is a major predictor of adverse outcomes in patients with acute ST-elevation myocardial infarction (STEMI). This study aimed to prospectively evaluate LVR in patients with STEMI who were successfully treated with primary percutaneous coronary intervention (PCI) and examine the relationship between early left ventricular dilation and late LVR.Methods: Overall 301 consecutive patients with STEMI who underwent primary PCI were included. Serial echocardiography was performed on the first day after PCI, on the day of discharge, at 1 month, and 6 months after discharge.Results: Left ventricular remodeling occurred in 57 (18.9%) patients during follow-up. Left ventricular end-diastolic volume (LVEDV) reduced from day 1 postoperative to discharge in the LVR group compared with that in the non-LVR (n-LVR) group. The rates of change in LVEDV (ΔLVEDV%) were -5.24 ± 16.02% and 5.05 ± 16.92%, respectively (p < 0.001). LVEDV increased in patients with LVR compared with n-LVR at 1-month and 6-month follow-ups (ΔLVEDV% 13.05 ± 14.89% vs. -1.9 ± 12.03%; 26.46 ± 14.05% vs. -3.42 ± 10.77%, p < 0.001). Receiver operating characteristic analysis showed that early changes in LVEDV, including ΔLVEDV% at discharge and 1-month postoperative, predicted late LVR with an area under the curve value of 0.80 (95% confidence interval 0.74-0.87, p < 0.0001).Conclusions: Decreased LVEDV at discharge and increased LVEDV at 1-month follow-up were both associated with late LVR at 6-month. Comprehensive and early monitoring of LVEDV changes may help to predict LVR.","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11229814/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41155101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0