Cardiology journal最新文献_第6页

Complete revascularization based on angiography derived fractional flow reserve versus incomplete revascularization in patients with ST-segment elevation myocardial infarction. ST段抬高型心肌梗死患者基于血管造影术得出的血流储备分数的完全血运重建与不完全血运修复。

Cardiology journal Pub Date : 2024-01-01 Epub Date: 2023-09-29 DOI: 10.5603/cj.92762

Jiahui Liu, Kaiping Zhang, Xingang Wang, Zhaoping Liu, Ming Chen, Fangfang Fan, Jia Jia, Tao Hong, Jianping Li, Yong Huo, Yanjun Gong, Bo Zheng

{"title":"Complete revascularization based on angiography derived fractional flow reserve versus incomplete revascularization in patients with ST-segment elevation myocardial infarction.","authors":"Jiahui Liu, Kaiping Zhang, Xingang Wang, Zhaoping Liu, Ming Chen, Fangfang Fan, Jia Jia, Tao Hong, Jianping Li, Yong Huo, Yanjun Gong, Bo Zheng","doi":"10.5603/cj.92762","DOIUrl":"10.5603/cj.92762","url":null,"abstract":"Background: Nearly half of ST-segment elevation myocardial infarction (STEMI) patients present with significant multivessel coronary artery disease, they are at high risk of subsequent adverse events. Whether complete revascularization guided by coronary angiography-derived fractional flow reserve (caFFR) further reduces such events risk is not fully investigated.Methods: In this study, 367 consecutive STEMI patients who underwent successful primary percutaneous coronary intervention (PCI) were enrolled. caFFR of all three coronary vessels were measured, including 367 culprit vessels and 703 non-culprit vessels. Complete revascularization was defined as post-PCI caFFR > 0.8 of all three coronary vessels. The primary endpoint was major adverse cardiovascular events (MACE, a composite of cardiovascular death, non-fatal recurrent myocardial infarction, ischemia-driven revascularization and non-fatal stroke/transient ischemic attacks) during follow-up.Results: At a median follow-up of 3.8 years, MACE had occurred in 39 patients of the 220 (17.7%) in the complete revascularization group as compared with 49 patients of the 131 (37.4%) in the incomplete revascularization group (hazard ratio [HR] 1.9; 95% confidence interval [CI] 1.2-3.0; p = 0.005). The incomplete revascularization in culprit vessels evaluated by caFFR showed the highest risk for MACE occurrence.Conclusions: In STEMI patients with multivessel coronary artery disease, incomplete revascularization based on caFFR might contribute to identifying patients at high-risk.","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"226-234"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11076025/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41171593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of homocysteine as a non-invasive and effort-free measurements for risk assessment of patients with pulmonary hypertension. 同型半胱氨酸作为一种无创、无需费力的测量方法在肺动脉高压患者风险评估中的应用。

Cardiology journal Pub Date : 2024-01-01 Epub Date: 2023-09-29 DOI: 10.5603/cj.92813

Mei-Tzu Wang, Pei-Ling Chi, Chin-Chang Cheng, Wei-Chun Huang, Lee-Wei Chen

{"title":"Application of homocysteine as a non-invasive and effort-free measurements for risk assessment of patients with pulmonary hypertension.","authors":"Mei-Tzu Wang, Pei-Ling Chi, Chin-Chang Cheng, Wei-Chun Huang, Lee-Wei Chen","doi":"10.5603/cj.92813","DOIUrl":"10.5603/cj.92813","url":null,"abstract":"Background: Current guideline-recommended multiparameters used to assess the risk levels of pulmonary arterial hypertension (PAH) are invasive hemodynamic measurements or effort-dependent exercise tests. Serum natriuretic peptide is only one kind of effort-free biomarker that has been adopted for risk assessment. This study aimed to investigate the application of homocysteine as a non-invasive and effort-free measurement for the risk assessment of patients with PAH.Methods: Samples of 50 patients diagnosed with PAH via right heart catheterization were obtained, and the patients were divided into low-, intermediate- and high-risk groups for further analysis. Additionally, serum N-terminal prohormone of B-type natriuretic peptide (NT-proBNP) and homocysteine levels of monocrotaline (MCT)-induced PAH rats were analyzed at each week with progressed severity of PAH, and they were sacrificed on day 28 with pathology being assessed.Results: Hyperhomocysteinemia was an independent predictor (odds ratio [OR]: 1.256; 95% confidence interval [CI]: 1.002-1.574) and showed a linear correlation with NT-proBNP. Hyperhomocysteinemia could discriminate between low/intermediate and high-risk levels in PAH with a cut-off value in 12 μmol/L. Moreover, the elevated homocysteine levels by weeks in MCT rats also demonstrated the association between homocysteine and the severity of PAH.Conclusions: Homocysteine can be a non-invasive and effort-free risk assessment for patients with pulmonary hypertension. Homocysteine level had a linear correlation with NT-proBNP level, and patients with hyperhomocysteinemia had a higher risk level, higher NT-proBNP level, and decreased lower diffusing capacity for carbon monoxide. The correlation between homocysteine level and PAH severity was also demonstrated in MCT rats.","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"285-299"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11076026/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41172545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Zero-fluoroscopy catheter ablation of premature ventricular contractions: comparative outcomes from the right ventricular outflow tract and other ventricular sites. 室性早搏的零荧光导管消融术：右室流出道和其他心室部位的比较结果。

Cardiology journal Pub Date : 2024-01-01 Epub Date: 2024-08-19 DOI: 10.5603/cj.98002

Dariusz Rodkiewicz, Karol Momot, Edward Koźluk, Agnieszka Piątkowska, Karolina Rogala, Liana Puchalska, Artur Mamcarz

{"title":"Zero-fluoroscopy catheter ablation of premature ventricular contractions: comparative outcomes from the right ventricular outflow tract and other ventricular sites.","authors":"Dariusz Rodkiewicz, Karol Momot, Edward Koźluk, Agnieszka Piątkowska, Karolina Rogala, Liana Puchalska, Artur Mamcarz","doi":"10.5603/cj.98002","DOIUrl":"10.5603/cj.98002","url":null,"abstract":"Background: The three-dimensional electroanatomic mapping (EAM) system allows performing catheter ablation (CA) without fluoroscopy in patients with premature ventricular contractions (PVCs). The right ventricle outflow tract (RVOT) location is favorable for performing zero-fluoroscopy CA. Non-RVOT zero-fluoroscopy CA is a challenging procedure. The study aimed to evaluate the efficacy and safety of zero-fluoroscopy CA using the EAM in patients with PVCs from RVOT and non-RVOT.Methods: Completely zero-fluoroscopy CA of PVCs guided by EAM was performed in 107 patients with PVCs. 54 patients underwent zero-fluoroscopy RVOT CA. The remaining 53 patients underwent zero-fluoroscopy non-RVOT CA. Demographic and clinical baseline characteristics, procedure parameters, and follow-up were obtained from medical records. Primary outcomes were the acute and the permanent success rate (12-month follow-up), complications, and procedure time.Results: There were no significant differences between groups regarding baseline characteristics. Acute procedural success was achieved in 52 patients (94,44%) in the RVOT zero-fluoroscopy CA group and in 45 patients (86,54%) in the non-RVOT zero-fluoroscopy CA group (ns). A long-term success rate was achieved in 50 patients (90,74%) in the RVOT zero-fluoroscopy CA group and in 44 patients (84,62%) in the non-RVOT zero-fluoroscopy CA group (ns). The median procedure time was 80.5 minutes in the RVOT group and 90 minutes in the non-RVOT group (ns). There were two complications in the non-RVOT group (ns).Conclusions: There were no differences in procedure time efficacy and safety zero-fluoroscopy ablation between RVOT and non-RVOT locations. Non-fluoroscopy CA of PVCs is a feasible, safe, and efficient procedure.","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"794-801"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11706260/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142001532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The hypothetical detrimental dog-bone effect during coronary angioplasty with compliant or non-compliant balloon. An in vitro experimental study. 使用顺应性或非顺应性球囊进行冠状动脉血管成形术时的假定有害狗骨效应。体外实验研究。

Cardiology journal Pub Date : 2024-01-01 Epub Date: 2024-10-24 DOI: 10.5603/cj.99667

François Derimay, Guillaume Cellier, Armida Gomez, Ricardo Copel, Jacques Ohayon, Gilles Rioufol, Gerard Finet

引用次数: 0

Scientific writing at the dawn of AI. 人工智能时代的科学写作

Cardiology journal Pub Date : 2024-01-01 DOI: 10.5603/cj.94335

Jarosław Meyer-Szary, Miłosz Jaguszewski, Szymon Mikulski

引用次数: 0

Reverse remodeling of mitral leaflets after medical treatment in recent-onset dilated cardiomyopathy. 新发扩张型心肌病药物治疗后二尖瓣叶反向重塑。

Cardiology journal Pub Date : 2024-01-01 Epub Date: 2024-05-14 DOI: 10.5603/cj.95415

Yu Kang, Nan Wang, Keyi Liu, Zixuan Yang, Nan Qu, Xueke Zhong, Xiaojing Chen, Mian Wang, Qing Zhang

{"title":"Reverse remodeling of mitral leaflets after medical treatment in recent-onset dilated cardiomyopathy.","authors":"Yu Kang, Nan Wang, Keyi Liu, Zixuan Yang, Nan Qu, Xueke Zhong, Xiaojing Chen, Mian Wang, Qing Zhang","doi":"10.5603/cj.95415","DOIUrl":"10.5603/cj.95415","url":null,"abstract":"Background: The growth of mitral leaflets (MLs) adaptive to left ventricluar (LV) remodeling has been observed. However, the elasticity of MLs upon mechanical stimuli would be supposed if it shrinks with LV reverse remodeling (LVRR).Material and methods: Patients with idiopathic recent-onset dilated cardiomyopathy (RODCM) (n = 82) and 50 matched normal controls (NC) were prospectively enrolled. Echocardiography was performed at baseline and 6 months of follow-up for the anterior and posterior mitral leaflet (AML and PML) length, mitral annular dimension (MAD), and tenting height (TH). LVRR was measured as a ≥ 15% reduction in LV end-diastolic volume (LVEDV).Results: After 6 months, LVRR was achieved in 69.5% of patients. The AML (28 ± 3 vs. 26 ± 3 mm, p = 0.004) and PML (19 ± 4 vs. 17 ± 3 mm, p < 0.001) decreased in length, as well as the MAD (31 ± 5 vs. 28 ± 5 mm, p = 0.001) and TH (10 ± 3 vs. 8 ± 2 mm, p < 0.001). Compared with the NC group, the AML and PML of the RODCM group were 16.7% and 35.7% longer at baseline and remained 8.3% and 21.2% longer at follow-up, respectively. The change in AML or PML correlated moderately with that in LVEDV (r = 0.487, p < 0.001; r = 0.516, p < 0.001, respectively). The AML and PML length decreased in the LVRR (+) subgroup (AML, 28 ± 3 vs. 26 ± 3 mm, p = 0.001; PML, 20 ± 4 vs. 16 ± 3 mm, p < 0.001), but remained the same in the LVRR (-) subgroup (27 ± 4 vs. 28 ± 4 mm, p = 0.318; 17 ± 3 vs. 17 ± 3 mm, p = 0.790).Conclusions: Enlarged MLs could reverse accompanied by LV reverse remodeling. This study provided the other facet of ML plasticity adaptive to mechanical stretching.","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"538-545"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11374336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140923947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of mild therapeutic hypothermia on platelet reactivity in comatose survivors of cardiac arrest with acute myocardial infarction treated with ticagrelor. 轻度低温治疗对替格瑞洛治疗的心脏骤停合并急性心肌梗死的昏迷幸存者血小板反应性的影响。

Cardiology journal Pub Date : 2024-01-01 Epub Date: 2022-05-06 DOI: 10.5603/CJ.a2022.0029

Julia M Umińska, Jakub Ratajczak, Krzysztof Pstrągowski, Katarzyna Buszko, Klaudiusz Nadolny, Tomasz Fabiszak, Klemen Steblovnik, Marko Noč, Jacek Kubica

{"title":"The impact of mild therapeutic hypothermia on platelet reactivity in comatose survivors of cardiac arrest with acute myocardial infarction treated with ticagrelor.","authors":"Julia M Umińska, Jakub Ratajczak, Krzysztof Pstrągowski, Katarzyna Buszko, Klaudiusz Nadolny, Tomasz Fabiszak, Klemen Steblovnik, Marko Noč, Jacek Kubica","doi":"10.5603/CJ.a2022.0029","DOIUrl":"10.5603/CJ.a2022.0029","url":null,"abstract":"Background: The aim of the study was to assess the antiplatelet effect of ticagrelor in patients with myocardial infarction (MI) after out-of-hospital cardiac arrest (OHCA) treated with percutaneous coronary intervention (PCI) and mild therapeutic hypothermia (MTH) vs. MI patients without OHCA treated with PCI.Methods: The study was designed and performed as a phase IV, single-center, investigator-initiated, prospective, observational study assessing the early pharmacodynamic effect (within first 24 h) of a ticagrelor loading dose (180 mg) in both groups of patients (MTH group vs. MI group). For assessment of ticagrelor pharmacodynamics Multiple Electrode Aggregometry (MEA) was applied.Results: Compared with the MTH group, platelet inhibition was persistently stronger in the MI group over the entire observation period (up to 24 h), with the highest differesnce at 4 hours after loading with ticagrelor (25.8 ± 26.4 vs. 75.8 ± 40.9 U, p = 0.002). As a consequence, there was a higher prevalence of high platelet reactivity in the MTH group, with the most explicit difference at 6 hours after the loading dose of ticagrelor (78% vs. 7%, p < 0.001).Conclusions: In comparison with patients treated with primary PCI for uncomplicated MI, the antiplatelet effect of ticagrelor in patients with MI complicated with OHCA, undergoing MTH and primary PCI, is attenuated and delayed.","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"472-478"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11229810/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42627184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predictive role of monocyte count for significant coronary artery disease identification in patients with stable coronary artery disease. 单核细胞计数对稳定型冠状动脉疾病患者重大冠状动脉疾病识别的预测作用。

Cardiology journal Pub Date : 2024-01-01 Epub Date: 2023-12-27 DOI: 10.5603/cj.95131

Tomasz Urbanowicz, Anna Olasińska-Wiśniewska, Michał Michalak, Anna Komosa, Krzysztof J Filipiak, Paweł Uruski, Artur Radziemski, Andrzej Tykarski, Marek Jemielity

{"title":"Predictive role of monocyte count for significant coronary artery disease identification in patients with stable coronary artery disease.","authors":"Tomasz Urbanowicz, Anna Olasińska-Wiśniewska, Michał Michalak, Anna Komosa, Krzysztof J Filipiak, Paweł Uruski, Artur Radziemski, Andrzej Tykarski, Marek Jemielity","doi":"10.5603/cj.95131","DOIUrl":"10.5603/cj.95131","url":null,"abstract":"Background: The coronary artery disease (CAD) remains the leading cause of morbidity that is characterized by broad spectrum of symptoms. Up to 30% of performed angiographies reveal normal coronary arteries. The aim of the study was to find simple predictor for significant epicardial artery stenosis among patients with chronic coronary syndrome.Methods: There were 187 patients (131 (709%) men and 56 (30%) women) in the median (Q1-Q3) age of 67 [58-72] presenting with stable CAD symptoms enrolled into the present retrospective analysis. The demographical, clinical and laboratory characteristics between patients with normal and significant coronary artery stenosis were compared.Results: The multivariable analysis revealed coexistence of hypercholesterolemia as significant differentiation factor (odds ratio [OR]: 4.38, 95% confidence interval [CI]: 1.78-10.80, p = 0.001) for significant CAD and inverse relation to serum high density lipoprotein (OR: 0.19, 95% CI: 0.05-0.72, p = 0.015) and relation to creatinine concentration (OR: 1.03, 95% CI: 1.00-1.05, p = 0.012). Among whole peripheral blood count analysis, the significant relation was noticed to be hemoglobin concentration (OR: 1.09, 95% CI: 1.10-1.18, p = 0.022) and monocyte count (OR: 32.3, 95% CI: 1.09-653.6, p = 0.017). Receiver operator curve revealed (AUC: 0.641, p = 0.001) with the optimal cut-off value above 0.45 K/uL for monocyte, yelding sensitivity of 81.82% and specificity of 58.06%.Conclusions: The peripheral monocyte count above 0.45 k/uL may be considered as a predictor of significant coronary artery disease in symptomatic patients with chronic coronary syndrome.","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"722-730"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11544409/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139041069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Temporary transvenous cardiac pacing in cathlab - myocardial infarction versus other causes - differences, complications, and prognosis. Data from a single-center retrospective analysis. 心电图室中的临时经静脉心脏起搏--心肌梗死与其他原因--差异、并发症和预后。来自单中心回顾性分析的数据。

Cardiology journal Pub Date : 2024-01-01 Epub Date: 2024-01-22 DOI: 10.5603/cj.95981

Tomasz Skowerski, Andrzej Kułach, Michał Kucio, Michał Majewski, Łukasz Maciejewski, Maciej Wybraniec, Zbigniew Gąsior

{"title":"Temporary transvenous cardiac pacing in cathlab - myocardial infarction versus other causes - differences, complications, and prognosis. Data from a single-center retrospective analysis.","authors":"Tomasz Skowerski, Andrzej Kułach, Michał Kucio, Michał Majewski, Łukasz Maciejewski, Maciej Wybraniec, Zbigniew Gąsior","doi":"10.5603/cj.95981","DOIUrl":"10.5603/cj.95981","url":null,"abstract":"Background: Transvenous temporary cardiac pacing (TTCP) is a lifesaving procedure, but the incidence of complications and prognosis depends on the underlying cause. The aim of this study was to compare the characteristics, complications, and prognosis in patients with myocardial infarction (MI) requiring TTCP vs. patients with TTCP due to other causes.Methods: The present analysis involved 244 cases in whom TTCP was performed between 2017 and 2021 in a high-volume cathlab. All the procedures were performed by an interventional cardiologist. MI constituted 46.3% of the patients (n = 113), including 63 ST-segment elevation MI patients (55.75%). Non-MI patients (control group) consisted of patients with any cause of bradycardia requiring TTCP.Results: Myocardial infarction patients requiring TTCP are younger and have a higher prevalence of hypertension and heart failure. The pacing lead is more frequently inserted during asystole/resuscitation, and pacing was needed for a longer time. MI patients required cardiac implantable electronic device implantation less frequently than in other causes (22% vs. 82%, p < 0.01). The incidence of TTCP complications did not differ. The incidence of in-hospital death was 6.5-fold higher in TTCP patients with MI. Logistic regression showed MI to be a strong predictor of in-hospital death (odds ratio: 8.1; 95% confidence interval: 1.3-57.9).Conclusions: In-hospital mortality in MI patients requiring TTCP is 6.5-fold higher than in other patients with bradycardia. The complication rate of TTCP is similar in MI and non-MI patients. It is not TTCP but the severity of MI itself and the fact that a pacing lead is frequently implanted in asystole or during resuscitation that is responsible for the higher mortality rate.","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"716-721"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11544405/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139514398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Heart failure with preserved ejection fraction: diagnostic value of HFA-PEFF score, H₂FPEF score, and the diastolic stress echocardiography. 射血分数保留型心力衰竭：HFA-PEFF 评分、H₂FPEF 评分和舒张期负荷超声心动图的诊断价值。

Cardiology journal Pub Date : 2024-01-01 Epub Date: 2024-04-08 DOI: 10.5603/cj.95191

Andrzej Kubicius, Zbigniew Gąsior, Maciej Haberka

{"title":"Heart failure with preserved ejection fraction: diagnostic value of HFA-PEFF score, H₂FPEF score, and the diastolic stress echocardiography.","authors":"Andrzej Kubicius, Zbigniew Gąsior, Maciej Haberka","doi":"10.5603/cj.95191","DOIUrl":"10.5603/cj.95191","url":null,"abstract":"Background: The aim of our study was to compare 3 diagnostic pathways: diastolic stress echocardiography (DSE) based on the ASE/EACVI 2016 guidelines, the 2018 H₂FPEF score, and the 2019 HFA-PEFF algorithm, in patients suspected of heart failure with preserved ejection fraction (HFpEF).Methods: The study group included 80 consecutive patients with a clinical suspicion of HFpEF. The H₂FPEF and HFA-PEFF scores and serum NT-proBNP concentrations were assessed in all the patients before they were sent for DSE.Results: The DSE-based pathway confirmed HFpEF in 17 (21%) patients, the HFA-PEFF algorithm in 43 (54%), and H₂FPEF scoring in 4 (5%) patients. The ROC analysis showed that HFA-PEFF score > 5 predicts a DSE-positive test with a sensitivity of 70.5% and a specificity of 65%, (AUC = 0.711, p = 0.002) with a negative predictive value of 89.1% and positive predictive value of 35.3%. The H₂FPEF score > 3 had a negative predictive value of 90%, a positive predictive value of 29.8%, and predicted positive DSE result with a sensitivity of 82.3% but rather poor specificity of 47.6% (AUC = 0.692, p = 0.004). Both H₂FPEF and HFA-PEFF showed similar predictive values (AUC) in the prediction of positive DSE test (p = ns).Conclusions: The HFA-PEFF score overestimated the rate of HFpEF in comparison to DSE and the H₂FPEF score. The H₂FPEF and HFA-PEFF scores showed only modest predictive values of the positive DSE and had a diagnostic power to rule out the HFpEF.","PeriodicalId":93923,"journal":{"name":"Cardiology journal","volume":" ","pages":"708-715"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11544415/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140864051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0