Biological research for nursing最新文献

{"title":"Editorial.","authors":"Carolyn Baratta Yucha","doi":"10.1177/10998004261436865","DOIUrl":"https://doi.org/10.1177/10998004261436865","url":null,"abstract":"","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004261436865"},"PeriodicalIF":2.1,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147488750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining mRNA-miRNA Interactions and Gene Expression in Overweight and Obesity.","authors":"Claudia Colina Prisco, Nicolaas H Fourie, Yupeng Wang, Meaghan Steck, Marcel de Jesús Vega, Letitia Y Graves-Dixon, Rosario B Jaime-Lara, Wendy A Henderson, Paule V Joseph","doi":"10.1177/10998004261433237","DOIUrl":"https://doi.org/10.1177/10998004261433237","url":null,"abstract":"<p><p>Obesity is characterized by excess adipose tissue, metabolic imbalance, and persistent low-grade inflammation, all of which can affect brain centers and their communication with peripheral organs. The genetic basis of obesity is complex, involving genetics, metagenomics, and gene-environment interactions that impact gene expression. Micro-RNAs (miRNAs) are small, single-stranded, non-coding RNAs that post-transcriptionally regulate the translational rates of target messenger RNAs (mRNAs). Exploring miRNA-mRNA interactions in obesity offers insights into molecular processes, potential biomarkers, and therapeutic targets of this condition. The current study examined the interplay between miRNA and mRNA collected from individuals with overweight and obesity, and normal weight controls. To our knowledge, this is the first experimental attempt to construct a comprehensive dataset of miRNA-mRNA interactions in overweight and obesity. Total RNA, including miRNA, was isolated from venous blood samples collected from 95 participants. Subsequently, 100 ng of RNA from each sample was analyzed using the NanoString quantitative assay. Quantile normalization, the Bayesian-based method Combat, multi-variable linear regression, over-representation, weighted gene correlation network analyses, and functional analyses were conducted. We found an association between IQGAP1 and DAZAP2 genes and miRNA-20-a and miRNA-2113. IQGAP1 and DAZAP2 were associated with insulin signaling and energy metabolism and insulin sensitivity, respectively. We also identified a positive correlation between peripheral cortisol levels and miRNA-548 with alterations in metabolic processes and the immune system. This suggests that miRNA-mRNA interactions in overweight and obesity may impact insulin sensitivity, metabolism, and immunity, providing novel insight into miRNA-mRNA interactions in overweight and obesity. (ClinicalTrials.gov identifier #NCT00824941; https://clinicaltrials.gov/study/NCT00824941).</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004261433237"},"PeriodicalIF":2.1,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147488743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of a Race-Based Stress Reduction Intervention on Sleep Quality, Melatonin Onset, and Inflammation in African American Women: Protocol for a Pilot Randomized Controlled Trial.","authors":"Sueyeon Lee, Linda Janusek, Sirimon Reutrakul, Alana Biggers, Herbert L Mathews, Chang Gi Park, Jacquelyn Y Taylor, Karen L Saban","doi":"10.1177/10998004261433563","DOIUrl":"https://doi.org/10.1177/10998004261433563","url":null,"abstract":"<p><p>African American women carry a disproportionate burden of cardiometabolic disease (CMD) risk and experience higher rates of sleep disturbances compared to other racial and ethnic groups. Sleep and the sleep-regulating hormone melatonin play key roles in modulating inflammation, a biological pathway central to CMD. Chronic exposure to racism and discrimination may exacerbate stress, disrupt sleep and melatonin rhythms, and elevate inflammatory responses, further heightening CMD risk. The purpose of this pilot study is to evaluate the effects of a race-based stress reduction intervention-Resilience, Stress, and Ethnicity (RiSE)-on sleep quality and dim-light melatonin onset (DLMO) as primary outcomes, and to examine inflammation as a secondary outcome among older African American women with CMD risk. Leveraging an ongoing randomized controlled trial (RCT) (R01AG081251), this embedded pilot RCT will randomize 32 women to either the RiSE intervention or an attention control health education program, both delivered via eight weekly online sessions. Sleep quality will be assessed using validated questionnaires and wrist-worn ActiGraph devices for seven nights. DLMO will be determined from seven salivary samples collected around habitual bedtime, and salivary cytokines will be measured for inflammation. All measures will be obtained pre- and post-intervention. This pilot study is the first to examine an integrative, race-based stress reduction intervention targeting sleep and melatonin rhythms in this population. Findings will inform future mechanistic studies and the development of nurse-led strategies to mitigate the adverse physiological consequences of discrimination-related stress on sleep and cardiometabolic health among African American women.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004261433563"},"PeriodicalIF":2.1,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147438450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of a Targeted Exercise Program on Pain, Balance, Proprioception, and Function in Adults With Knee Osteoarthritis.","authors":"Vahid Mohammadi, Saeedeh Mohebitabar, Gholam Rasul Mohammad Rahimi","doi":"10.1177/10998004261425677","DOIUrl":"https://doi.org/10.1177/10998004261425677","url":null,"abstract":"<p><p>Knee osteoarthritis (OA) is associated with pain and reduced functional performance, increasing fall risk in older adults. While conventional physiotherapy is widely used, limited evidence exists regarding the added value of exercise programs on proprioception and balance outcomes. This study aimed to evaluate the effects of a structured four-week exercise program, in combination with conventional physiotherapy, on function, pain, proprioception, and balance in adults with knee OA. Thirty participants (aged 50-65 years) with clinically diagnosed knee OA were randomly assigned to either an experimental group (<i>n</i> = 15), which received conventional physiotherapy (including electrotherapy, manual therapy, and therapeutic modalities) combined with structured exercise, or a control group (<i>n</i> = 15), which received conventional physiotherapy alone. Outcome measures included knee function, pain, proprioception, and static balance. Data were analyzed using repeated measures ANOVA. Both groups showed significant pre-to post-test improvements across all outcomes (<i>p <</i> .05). However, the experimental group achieved markedly greater gains in proprioception (-33.85% and -36.04% at 30° and 60°, respectively), static balance (+25.13% eyes-open, +42.25% eyes-closed), and functional reach (+10.87%) compared with the control group. Pain reduction was also greater in the experimental group (-28.02% vs. -19.37%). Improvements in knee function were observed in both groups, with no significant group-by-time interaction. Integrating a targeted exercise program with physiotherapy leads to superior improvements in sensorimotor and functional outcomes in individuals with knee OA. These findings support non-pharmacological strategies to enhance mobility and reduce fall risk in this population.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004261425677"},"PeriodicalIF":2.1,"publicationDate":"2026-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146145001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Insights Into Maternal Antidepressant Use and the Human Infant Gut Microbiome.","authors":"Katelyn Desorcy-Scherer, Kerry McNamara, Ryan Luellwitz, Eliot Stanton, Ibrahim Zuniga-Chaves","doi":"10.1177/10998004261423546","DOIUrl":"https://doi.org/10.1177/10998004261423546","url":null,"abstract":"<p><p>Maternal selective serotonin reuptake inhibitor (SSRI) use is common during pregnancy and lactation. Changes in serotonin signaling may affect diversity and composition of microbes in the gut. Although research suggests SSRI drives microbial change, the extent to which the infant gut microbiome is affected is unknown. The infant gut microbiome is critical in early life for support of developmental health including early training of the immune system and metabolic programming. A total of <i>N</i> = 20 (10 SSRI, 10 control) maternal/infant dyads were enrolled in a pilot study. Thirty-six infant stool samples were collected at 1-2 and 4-6 weeks of life and sequenced using 16S rRNA sequencing. Investigative models included SSRI exposure as the primary variable of interest with infant feeding pattern and mode of delivery included as covariates. Maternal antidepressant use was not associated with infant alpha (within-sample) diversity. The SSRI use may shape beta (between-sample) diversity, particularly at weeks 4-6 of life (<i>p =</i> .072). Increases in the genera <i>Gemella</i>, <i>Staphylococcus</i> and <i>Corynebacterium</i> were observed with SSRI exposure. Additionally, results reveal a SSRI-associated decrease in <i>Lactobacillus</i>. While this pilot study is not intended to provide conclusive evidence, it is an important step in informing future research directions. Results suggest a modest influence of maternal SSRI exposure on the infant gut microbiome. Future studies should seek to use techniques like metagenomics, providing functional information to assess for local or systemic health impact and ultimately, clinical relevance.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004261423546"},"PeriodicalIF":2.1,"publicationDate":"2026-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146133075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex Differences in Pain Sensitivity Among Cognitively Healthy Older Adults.","authors":"Aaron L McDaniel, Jeffrey T Boon, Todd B Monroe, Asvena Siva, Ashleigh Fletcher, Karen O Moss, Stephen Bruehl, Mary S Dietrich, Ronald L Cowan, Michelle Crum, Michelle D Failla","doi":"10.1177/10998004261422188","DOIUrl":"https://doi.org/10.1177/10998004261422188","url":null,"abstract":"<p><p><b>Objective:</b> This study examined sex differences in pain intensity and unpleasantness among cognitively healthy older adults. While females generally exhibit heightened pain sensitivity, research on sex differences in older adults remains limited. We aimed to determine whether these differences persist in aging populations without cognitive impairment. <b>Methods:</b> A sample of 58 community-dwelling older adults (≥60 years, 34 females, 24 males) were included in this pain psychophysics study to assess differences by sex. Cognitive status was assessed using the Mini-Mental Status Exam (MMSE) or Telephone Interview for Cognitive Status (TICS). Depression, anxiety, and baseline pain were also assessed. Evoked heat pain stimuli at fixed temperatures (34°C, 39°C, 44°C) were delivered via the Medoc Q-Sense system with pain intensity and unpleasantness rated immediately after each stimulus. <b>Results:</b> Females reported significantly higher pain intensity than males (<i>p =</i> .02; female mean = 4.6 [95% CI: 3.9, 5.3], male mean = 3.5 [95% CI: 2.9, 4.2]). Sex differences in reported pain intensity were consistent across the three stimulus intensity levels (sex by temperature interaction <i>p =</i> .35). Pain unpleasantness did not differ significantly between sexes (<i>p =</i> .14) nor was the sex by temperature interaction significant (<i>p =</i> .35). <b>Conclusion:</b> Findings confirm sex differences in perceived pain intensity among cognitively healthy older adults, with females reporting higher pain levels. In contrast, no significant sex differences were observed in the affective component of pain. These results underscore the importance of incorporating sex-specific considerations in the assessment and management of pain intensity in older adults.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004261422188"},"PeriodicalIF":2.1,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146121298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating Sex Differences in Biomarkers of Chronic Pain Among Active-Duty Personnel: An Exploratory Analysis of a Pragmatic Clinical Trial With a SMART Design.","authors":"Sotaro Shimada, Shannon Ledesma, Diane M Flynn, Nathan Tintle, Jeffrey C Ransom, Honor M McQuinn, Tyler J Snow, Nicholas Ieronimakis, Dahee Wi, Larisa A Burke, Alana D Steffen, Ardith Z Doorenbos","doi":"10.1177/10998004261423210","DOIUrl":"10.1177/10998004261423210","url":null,"abstract":"<p><p>Chronic pain affects approximately one-third of active-duty service members (ADSMs), yet effective treatment remains challenging. Salivary cortisol and urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG) are established non-invasive biomarkers of stress and oxidative DNA damage and may provide reliable unbiased indicators of treatment efficacy in chronic pain. However, their associations with pain outcomes and potential sex differences remain unclear. It was hypothesized that interdisciplinary pain treatment would result in decreased levels of stress and oxidative DNA damage biomarkers, as well as decreased pain intensity, and that the magnitude of challenge might vary by sex. Our objective was to compare longitudinal changes in salivary cortisol and urinary 8-OHdG in relation to pain outcomes and sex. A total of 190 ADSMs who referred for chronic pain treatment completed data collection on the Patient-Reported Outcomes Measurement Information System (PROMIS) measures and urine and saliva samples at baseline and post-treatment. Multivariable regression models were used to predict changes in PROMIS scores relative to changes in cortisol and 8-OHdG, while adjusting for baseline levels. Interaction terms between participants' sex and changes in biomarkers were added to each model. Given the study's exploratory nature, a significance threshold of <i>p</i> < .10 was used for all analyses. Five statistically significant sex-by-cortisol interactions were identified for pain measures (pain impact, pain interference, physical functioning, sleep impairment, and social functioning), but none for 8-OHdG. Future work is needed to replicate these findings in larger samples. The research protocol was registered in ClinicalTrials.gov (NCT03297905; https://clinicaltrials.gov/study/NCT03297905).</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004261423210"},"PeriodicalIF":2.1,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146115225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Associated With Obstructive Sleep Apnea Among Community-Based Overweight and Obese Type 2 Diabetes Mellitus Patients: A Multisite Cross-Sectional Study.","authors":"Mei-Hsiang Lin, Ping-Ru Hsiao, Ning-Hung Chen, Chao-Chung Ho, Hsiu-Chin Hsu","doi":"10.1177/10998004261423490","DOIUrl":"https://doi.org/10.1177/10998004261423490","url":null,"abstract":"<p><p><b>Background:</b> Although obstructive sleep apnea (OSA) frequently coexists with type 2 diabetes mellitus (T2DM), many cases remain undiagnosed, particularly among overweight or obese individuals. Objectives: This study aimed to determine the risk factors associated with OSA among overweight or obesity T2DM. <b>Methods:</b> A multicenter cross-sectional descriptive design was conducted from September 2023 to April 2024. A total of 422 T2DM participants were recruited from four Diabetes Shared Care Network clinics in Taiwan. The Pittsburgh Sleep Quality Index, Epworth Sleep Scale, and a portable sleep monitoring device were used for data collection. A hierarchical multiple regression analysis was conducted to identify the factors affecting T2DM patients with OSA, and a multinomial logistic regression analysis was used to examine the major influence factors for each OSA severity level. <b>Results:</b> 80.3% of the T2DM participants were found to have OSA; 51.8% had moderate to severe OSA. After controlling the confounding variables, age, number of comorbidities, BMI, neck circumference, snoring times, and pulse rate were significant predictors of Apnea-Hypopnea Index (AHI). Furthermore, severe OSA was significantly related to age, BMI, gender, pulse rate, and snoring times. <b>Conclusions:</b> Up to 80.3% of participants with T2DM were found to have OSA. Higher BMI, neck circumference, number of comorbidities, age, pulse rate, and snoring frequency were significantly associated with OSA. Notably, BMI and age were the most significant predictors across mild, moderate, and severe OSA. Therefore, it is strongly recommended that patients with overweight or obese T2DM undergo routine OSA screening to ensure timely diagnosis and optimize management.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004261423490"},"PeriodicalIF":2.1,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146108921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study Protocol for a Randomized Controlled Trial of Multisensory Early Oral Administration of Human Milk (M-MILK) for Very Preterm Infants: Enhancing Stress Regulation, Neurodevelopment, and Oral Feeding Skills.","authors":"Thao Griffith, Linda Janusek, Rosemary White-Traut, Stefan J Green, Amin Sachin, Cara Joyce","doi":"10.1177/10998004261418708","DOIUrl":"10.1177/10998004261418708","url":null,"abstract":"<p><p><b>Background</b>. Early life stress results in disrupted stress regulation, and less optimal neurodevelopment and oral feeding skills in very preterm infants. Despite these associations, there are few evidence-based interventions to help these fragile infants during critical stages of development. <b>Purpose</b>. This article describes an ongoing research protocol of a randomized controlled trial (RCT) to evaluate the <i>m</i>ultisensory early oral administration of human <i>milk</i> (M-MILK) as an early NICU intervention to improve stress regulation, support optimal neurodevelopment, and promote competent oral feeding skills in very preterm infants. <b>Method</b>. M-MILK is an infant-led early NICU intervention beginning on day 3 of life to provide very preterm infants with small droplets of milk orally while engaging their innate senses. Infants (N = 124) born <32 weeks gestational age are randomized to either the M-MILK or control group (standard of care). M-MILK begins on day 3 of life. We assess stress regulation, neurodevelopment, and oral feeding skills over time via salivary cortisol, buccal cell DNA methylation, NeoNatal Neurobehavioral Scale, Ages and Stages Questionnaire, Early Feeding Skills Assessment, and Neonatal Feeding Assessment Tool. Endpoints will be compared by treatment arm using linear regression and mixed-effects models for cross-sectional and longitudinal analyses, respectively. <b>Discussion</b>. Findings from this study will advance knowledge as to the efficacy of M-MILK as an epigenetically-informed intervention to enhance stress regulation, neurodevelopment, and oral feeding skills in very preterm infants during critical periods of neuroplasticity. The study has been registered at https://ClinicalTrials.gov (NCT07216664).</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004261418708"},"PeriodicalIF":2.1,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12974252/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146004704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of I-Shaped Kinesiotaping on Pain, Functionality, and Wound Healing After Lumbar Disc Surgery: A Randomised Controlled Trial.","authors":"Gülşah Bilgin, Emine Öncü, Melih Çekinmez","doi":"10.1177/10998004261416820","DOIUrl":"https://doi.org/10.1177/10998004261416820","url":null,"abstract":"<p><p>Background and AimKinesiotape is commonly used as a complementary therapy, but its results can vary substantially. This study aims to evaluate the effects of I-shaped kinesiotaping on patients' pain levels, functionality, and wound healing after lumbar disc surgery.DesignPlacebo-randomized controlled trial.SettingsA public hospital.ParticipantsEighty patients undergoing lumbar discectomy, with a mean age of 49.9 ± 13.1 years, were randomized to either the kinesiotaping (kinesio) or placebo group.InterventionThe kinesio group had I-shaped kinesiotape applied 24 hours after surgery and on postoperative days 5, 10, 15, and 20, while the placebo group received placebo taping.Main MeasuresA visual analog scale for pain, analgesic medication use, the Oswestry Disability Index, the Functional Low Back Pain Scale, and wound healing were assessed on the 1st, 5th, 10th, 15th, and 30th days post-surgery.ResultsSignificant time effects were observed for both groups, with the kinesio group showing reductions in pain, analgesic medication use, and disability, along with improvements in functionality (effect size ƞ² = 0.435-0.713, <i>p</i> < 0.001). The placebo group showed similar changes (effect size ƞ² = 0.567-0.714, <i>p</i> < 0.001). No significant group or interaction effects were found.ConclusionsPost-lumbar disc surgery, kinesiotaping did not show significant advantages in pain control, analgesic use reduction, disability improvement, or wound healing. The trial protocol is available on https://ClinicalTrials.gov (NCT05476718) (https://clinicaltrials.gov/study/NCT05476718).</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004261416820"},"PeriodicalIF":2.1,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145961061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}