Biological research for nursing最新文献

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Serial Mediation: How Optimism Reduces and Pessimism Intensifies Chronic Low Back Pain Through Depression and Biological Aging. 系列中介:乐观如何通过抑郁和生物老化减少和加剧慢性腰痛。
Biological research for nursing Pub Date : 2025-06-03 DOI: 10.1177/10998004251348910
Khalid W Freij, Fiona B A T Agbor, Vinodh Srinivasasainagendra, Tammie L Quinn, Hemant K Tiwari, Robert E Sorge, Burel R Goodin, Edwin N Aroke
{"title":"Serial Mediation: How Optimism Reduces and Pessimism Intensifies Chronic Low Back Pain Through Depression and Biological Aging.","authors":"Khalid W Freij, Fiona B A T Agbor, Vinodh Srinivasasainagendra, Tammie L Quinn, Hemant K Tiwari, Robert E Sorge, Burel R Goodin, Edwin N Aroke","doi":"10.1177/10998004251348910","DOIUrl":"https://doi.org/10.1177/10998004251348910","url":null,"abstract":"<p><p>There is growing evidence that psychological (e.g., optimism, pessimism, depressive symptoms) and biological factors play an essential role in the experience of chronic low back pain (CLBP). This study aimed to examine the nature of the relationship between optimism or pessimism, depressive symptoms, the pace of biological aging, CLBP severity, and interference. Using mediation analysis, we tested the hypothesis that depressive symptoms and pace of biological aging measured using the Dunedin Pace of Aging from the Epigenome (DunedinPACE) serially mediate the relationship between optimism or pessimism and CLBP severity and interference. Our sample included non-Hispanic Black and non-Hispanic White adults aged 18-82 years: 74 without pain, 56 with low-impact pain, and 77 with high-impact pain. On average, individuals with high-impact pain reported lower levels of optimism, greater pessimism, and faster DunedinPACE than those in the low-impact or no-pain group (<i>p</i> < .05). Mediation analyses revealed indirect associations between both optimism and pessimism with pain severity and interference serially via depressive symptoms and the pace of biological aging (<i>p</i> < .05). These indirect effects were not statistically significant after controlling for chronological age, sex, race, and BMI. The results suggest that psychological interventions that increase optimism and reduce pessimism may slow the biological aging process, which may improve nonspecific CLBP outcomes in non-Hispanic Black and non-Hispanic White adults.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004251348910"},"PeriodicalIF":0.0,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in DNA Methylation Associated With Psychobehavioral Interventions: A Scoping Literature Review. 与心理行为干预相关的DNA甲基化变化:范围文献综述。
Biological research for nursing Pub Date : 2025-05-31 DOI: 10.1177/10998004251346179
Karen L Saban, Linda Janusek, Paula de la Pena, Sueyeon Lee, Dina Tell, Herbert Mathews, Alexandra L Nowak, Alexandria Nyembwe, Jacquelyn Y Taylor
{"title":"Changes in DNA Methylation Associated With Psychobehavioral Interventions: A Scoping Literature Review.","authors":"Karen L Saban, Linda Janusek, Paula de la Pena, Sueyeon Lee, Dina Tell, Herbert Mathews, Alexandra L Nowak, Alexandria Nyembwe, Jacquelyn Y Taylor","doi":"10.1177/10998004251346179","DOIUrl":"https://doi.org/10.1177/10998004251346179","url":null,"abstract":"<p><p><b>Background:</b> DNA methylation (DNAm) is an epigenetic process of addition or reduction of methyl groups to genes that modify gene expression and can alter the physiological response to psychological stress. DNAm associated with psychological stress is malleable, making it a prime target for psychobehavioral interventions. Research is beginning to examine changes in DNAm in response to psychobehavioral interventions, such as mindfulness-based stress reduction, cognitive behavioral therapy, and yoga. A better understanding of the current evidence may provide direction for future research. <b>Objective:</b> The purpose of this scoping review is to summarize current studies, identify knowledge gaps, and make recommendations for further research related to examining alterations in DNAm in response to psychobehavioral interventions. <b>Methods:</b> A scoping review was conducted based on the methods recommended by Arksey and O'Malley (2005). Studies examining response of blood or saliva DNAm to psychobehavioral interventions in adult humans were reviewed. <b>Results:</b> Twenty-one studies met the inclusion criteria. Although many studies were inadequately powered, several reported differences in DNAm in response to a psychobehavioral intervention across a variety of genes, including genes related to stress and inflammation. However, the studies varied with respect to participant health status, type and duration of psychobehavioral interventions evaluated, biospecimens examined, and method of DNA analysis. <b>Conclusions:</b> The evaluation of DNAm in response to psychobehavioral interventions is a growing area of research. Future research is needed to address design limitations of existing investigations, evaluate the biological importance of observations, and link the DNAm response to physiological and psychological outcomes of the interventions.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004251346179"},"PeriodicalIF":0.0,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144192604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation Between Glycemic Variability in Patients With Intracerebral Hemorrhage and Neurological Deterioration. 脑出血患者血糖变异性与神经功能恶化的关系。
Biological research for nursing Pub Date : 2025-05-21 DOI: 10.1177/10998004251344888
Lichun Lu, Xiangyi Yin, Chen Wang, Xianlan Meng, Gongbo Li, Wenyu Zhu
{"title":"Correlation Between Glycemic Variability in Patients With Intracerebral Hemorrhage and Neurological Deterioration.","authors":"Lichun Lu, Xiangyi Yin, Chen Wang, Xianlan Meng, Gongbo Li, Wenyu Zhu","doi":"10.1177/10998004251344888","DOIUrl":"https://doi.org/10.1177/10998004251344888","url":null,"abstract":"<p><p><b>Background:</b> Glycemic variability and its management hold significant prognostic implications in clinical practice for patient outcomes. The aim of this study is to analyze the correlation between glycemic variability and the deterioration of neurological function in patients with intracerebral hemorrhage (ICH), to provide evidence-based support for the treatment and care of clinical ICH patients. <b>Methods:</b> Patients with ICH admitted to our hospital between January 2022 and August 2024 were subjected to the National Institutes of Health Stroke Scale (NIHSS) scoring upon admission and discharge. A comparative analysis of baseline characteristics and glycemic variability parameters was conducted. <b>Results:</b> A total of 156 patients with ICH were included. The incidence of neurological deterioration in ICH patients was 30.8%. Correlation analysis revealed significant associations between age (r = 0.602), mean glucose levels (r = 0.623), Time in Range (TIR) (r = 0.589), Mean Amplitude of Glycemic Excursions (MAGE) (r = 0.608), and Large Amplitude of Glycemic Excursions (LAGE) (r = 0.634) with the occurrence of neurological deterioration. Logistic regression analysis identified age (OR = 2.512, 95%CI: 1.924-3.006), mean glucose (OR = 2.743, 95%CI: 2.101-3.286), TIR (OR = 3.204, 95%CI: 2.985-3.607), MAGE (OR = 3.029, 95%CI: 2.601-3.748), and LAGE (OR = 2.768, 95%CI: 2.245-3.103) as significant predictors of neurological deterioration in ICH patients. <b>Conclusion:</b> This finding underscores the critical importance of considering both chronological age and glycemic control metrics in the prognostic evaluation of ICH patients. Integrating these factors into clinical assessments may enhance the accuracy of predicting patient outcomes and guide tailored therapeutic strategies.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004251344888"},"PeriodicalIF":0.0,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144113040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurological Post-Acute Sequelae of COVID-19 in Non-Hospitalized Patients: An Integrative Review. 非住院患者COVID-19急性后神经系统后遗症:一项综合综述
Biological research for nursing Pub Date : 2025-05-05 DOI: 10.1177/10998004251335968
Jose Carlos de Andrade Vieira Junior, Murilo Rossi Lima Sander, José Airton de Oliveira Matos, André de Macêdo Medeiros, Flávio Santos da Silva, Caio Augusto Martins Aires
{"title":"Neurological Post-Acute Sequelae of COVID-19 in Non-Hospitalized Patients: An Integrative Review.","authors":"Jose Carlos de Andrade Vieira Junior, Murilo Rossi Lima Sander, José Airton de Oliveira Matos, André de Macêdo Medeiros, Flávio Santos da Silva, Caio Augusto Martins Aires","doi":"10.1177/10998004251335968","DOIUrl":"https://doi.org/10.1177/10998004251335968","url":null,"abstract":"<p><p>The COVID-19 pandemic has had a significant impact on the global population. The infection, caused by SARS-CoV-2, presents with a variety of clinical manifestations, from asymptomatic cases to more severe forms, including a variety of neurological symptoms, such as fatigue, weakness, brain fog, paresthesias, dysautonomia, anosmia, and dysgeusia. Additionally, the disease is associated with the long COVID syndrome, in which there is persistence of the effects and symptoms of the acute phase. In recent years the literature has shown relevant data on long COVID, but there is still a need to deepen the knowledge about these long term manifestations. Thus, the present study aimed to describe the main neurological sequelae resulting from SARS-CoV-2 infection in non-hospitalized population during the long phase of the disease, gathering scientific evidence through an integrative review of the prevalence of symptoms, patient profile, duration and severity of sequelae, risk factors, comorbidities, and possible nervous system structural damage. The PubMed/Medline database was used with descriptors and, at the end of the screening process with predefined inclusion and exclusion criteria, 22 studies were included. A group of neurological symptoms associated with long COVID was identified: myalgia, dysgeusia, memory alterations, olfactory dysfunction, dizziness, and pain. Most patients presented multiple symptoms that lasted for more than one year with a significant impact on quality of life. The main risk factors were dyslipidemia, age, ethnicity, muscle/ joint pain, and sex. This review highlights the importance of further studies on the syndrome, its etiology, diagnosis, follow-up, and treatments.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004251335968"},"PeriodicalIF":0.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144015072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sleep and Adiposity Outcomes in School-Age Children with Overweight and Obesity. 超重和肥胖学龄儿童的睡眠和肥胖结局。
Biological research for nursing Pub Date : 2025-05-05 DOI: 10.1177/10998004251339743
Shao-Yu Tsai, Yi-Ching Tung, Chuen-Min Huang, Shu-Yu Kuo, Chien-Chang Lee
{"title":"Sleep and Adiposity Outcomes in School-Age Children with Overweight and Obesity.","authors":"Shao-Yu Tsai, Yi-Ching Tung, Chuen-Min Huang, Shu-Yu Kuo, Chien-Chang Lee","doi":"10.1177/10998004251339743","DOIUrl":"https://doi.org/10.1177/10998004251339743","url":null,"abstract":"<p><p><b>Purpose:</b> To examine four dimensions of sleep (timing, quality, quantity, and variability) and their association with adiposity outcomes in a community sample of school-age children with overweight and obesity. <b>Design</b>: A cross-sectional actigraphic study. <b>Methods:</b> 246 school-age children aged 6-9 years with overweight or obesity were recruited from 10 public elementary schools in Taipei, Taiwan. Children's sleep was objectively assessed over a 7-day period using a wrist actigraph. Adiposity outcomes, including BMI, BMI-for-age z-score, and percent body fat, were computed based on measured weight, height, and skinfold thickness following standardized procedures. Associations between sleep and child adiposity outcomes were examined using bivariate and multiple linear regression analyses. <b>Results:</b> In the bivariate analyses, later sleep onset time was correlated with greater percent body fat (<i>p =</i> .01); shorter daily sleep duration was correlated with higher BMI and percent body fat (both <i>p <</i> .05); greater variability in daily sleep duration was correlated with higher BMI, BMI-for-age z-score, and percent body fat (all <i>p <</i> .05). In multiple linear regression analyses, variability in daily sleep duration was the only sleep characteristic that showed a statistically significant association with percent body fat in children (b = 2.36; 95% CI: 0.28 to 4.43; <i>p =</i> .02). <b>Conclusions:</b> Overweight and obesity treatment interventions targeting child weight management should prioritize the assessment and promotion of children's sleep regularity. Future randomized controlled trials are needed to investigate the impact of maintaining a more consistent sleep pattern on measures of adiposity in school-age children with overweight and obesity.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004251339743"},"PeriodicalIF":0.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of Eight Weeks of Aerobic Exercise and Spirulina Supplementation on Some Liver Enzymes, Body Composition, and Cardiorespiratory Fitness in Overweight and Obese Adult Women. 8周有氧运动和补充螺旋藻对超重和肥胖成年女性某些肝酶、体成分和心肺健康的影响
Biological research for nursing Pub Date : 2025-04-30 DOI: 10.1177/10998004251340024
Haniyeh Akbarzadeh Khadari, Rokhsare Fazolahzade Mousavi, Ladan Hosseini Abrishami
{"title":"The Effect of Eight Weeks of Aerobic Exercise and Spirulina Supplementation on Some Liver Enzymes, Body Composition, and Cardiorespiratory Fitness in Overweight and Obese Adult Women.","authors":"Haniyeh Akbarzadeh Khadari, Rokhsare Fazolahzade Mousavi, Ladan Hosseini Abrishami","doi":"10.1177/10998004251340024","DOIUrl":"https://doi.org/10.1177/10998004251340024","url":null,"abstract":"<p><p><b>Objective:</b> This study aimed to evaluate the effects of eight weeks of aerobic exercise and spirulina supplementation on liver enzymes, body composition, and cardiorespiratory fitness in overweight and obese women. <b>Methods:</b> A randomized, double-blind, placebo-controlled trial was conducted involving 36 overweight and obese adult women (body mass index [BMI] ≥ 25 kg/m<sup>2</sup>, aged 25-40 years) randomly assigned to four groups: placebo with aerobic exercise, spirulina with aerobic exercise, spirulina-only, and placebo-only. Interventions included aerobic training three times per week (40-50 minutes/session) and a twice-daily dose (each 500 mg) of Spirulina or placebo for eight weeks. Outcomes were assessed at baseline and post-intervention, including liver enzyme levels (alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP), body composition (BMI, body fat percentage, waist-to-hip ratio (WHR)), and VO<sub>2max</sub> using validated protocols. <b>Results:</b> Significant within-group improvements in ALT, AST, body weight, BMI, WHR, and VO<sub>2</sub>max were observed in the aerobic training and spirulina groups, either alone or combined (<i>p <</i> .001). The aerobic training + placebo group demonstrated the greatest reduction in body weight and BMI, while spirulina-alone showed significant ALT and AST reductions. VO<sub>2max</sub> improved in all intervention groups, but post hoc analysis revealed no significant between-group differences. <b>Conclusion:</b> Aerobic exercise and spirulina supplementation independently and synergistically improve liver function, body composition, and cardiorespiratory fitness in overweight and obese women. Combining these interventions may offer a holistic approach to managing obesity-related health risks. Further research is essential to elucidate the underlying mechanisms and optimize intervention strategies for diverse populations.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004251340024"},"PeriodicalIF":0.0,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of 6 Weeks of Dynamic Neuromuscular Stabilization Exercises on Motor Control, Cardiovascular Fitness, and Respiratory Performance in Overweight and Obese Women. 6周动态神经肌肉稳定训练对超重和肥胖女性运动控制、心血管健康和呼吸功能的影响
Biological research for nursing Pub Date : 2025-04-25 DOI: 10.1177/10998004251337451
Sara Binabaji, Nasser Mohammad Rahimi, Mahdi Esfahani
{"title":"The Effect of 6 Weeks of Dynamic Neuromuscular Stabilization Exercises on Motor Control, Cardiovascular Fitness, and Respiratory Performance in Overweight and Obese Women.","authors":"Sara Binabaji, Nasser Mohammad Rahimi, Mahdi Esfahani","doi":"10.1177/10998004251337451","DOIUrl":"https://doi.org/10.1177/10998004251337451","url":null,"abstract":"<p><p><b>Background:</b> Obesity is linked to impairments in motor control, cardiovascular fitness, and respiratory function. Dynamic Neuromuscular Stabilization (DNS) aims to enhance core stability, diaphragmatic breathing, and neuromuscular coordination. This study investigated the effects of a 6-week DNS program on these functional outcomes in overweight and obese women. <b>Methods:</b> Thirty-six participants (aged 35-50 years, BMI: 25-34 kg/m<sup>2</sup>) were randomly assigned to either an experimental group (<i>n</i> = 18), which underwent DNS training, or a control group (<i>n</i> = 18), which received no intervention. The DNS program consisted of six weekly sessions (three supervised, three home-based), emphasizing core stabilization, diaphragmatic breathing, and neuromuscular coordination. Motor control (lumbar movement control tests), cardiovascular fitness (two-minute step test), and respiratory performance (breath-hold time, respiratory rate, and respiratory muscle strength) were assessed before and after the intervention. <b>Results:</b> The DNS group demonstrated significant improvements compared to the control group, with notable increases in motor control scores (<i>p <</i> .001) and cardiovascular fitness (<i>p <</i> .001). Additionally, inspiratory and expiratory breath-hold times (<i>p <</i> .001 for both), respiratory rate (<i>p <</i> .001), and maximum inspiratory and expiratory pressures (<i>p <</i> .001) showed substantial enhancements. No significant changes were observed in the control group. <b>Conclusion:</b> A 6-week DNS exercise program significantly improved motor control, cardiovascular fitness, and respiratory performance in overweight and obese women. These findings support DNS training as an effective intervention for enhancing core stability, breathing efficiency, and neuromuscular coordination, with potential applications in rehabilitation and health promotion.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004251337451"},"PeriodicalIF":0.0,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Functional Training on Physical Function, Cardiorespiratory Fitness, and Quality of Life in Older Women: A 6-Week Randomized Controlled Trial. 功能训练对老年妇女身体功能、心肺健康和生活质量的影响:一项为期6周的随机对照试验
Biological research for nursing Pub Date : 2025-04-24 DOI: 10.1177/10998004251337063
Akram Dashti, Nasser Mohammad Rahimi, Amin Azimkhani
{"title":"Effects of Functional Training on Physical Function, Cardiorespiratory Fitness, and Quality of Life in Older Women: A 6-Week Randomized Controlled Trial.","authors":"Akram Dashti, Nasser Mohammad Rahimi, Amin Azimkhani","doi":"10.1177/10998004251337063","DOIUrl":"https://doi.org/10.1177/10998004251337063","url":null,"abstract":"<p><p><b>Background:</b> Functional training is increasingly recognized for its potential to improve physical function and quality of life (QoL) in older adults. This randomized controlled trial examined the effects of a six-week functional training program on physical function, cardiorespiratory fitness, and QoL in older women. <b>Methods:</b> Fifty older women (mean age: 63.5 ± 3.7 years) were randomly assigned to a functional training group (<i>n</i> = 25) or a control group (<i>n</i> = 25). The intervention group participated in a six-week functional training program (six sessions per week), while the control group maintained usual daily activities. Outcomes included dynamic balance (TUG test), flexibility, muscle strength, walking speed, cardiorespiratory fitness (two-minute step test), and QoL. <b>Results:</b> Functional training significantly improved dynamic balance, lower body flexibility, lower body strength, walking speed, and aerobic endurance (<i>p</i> < .05 for all). QoL significantly increased in the functional training group across all domains, as well as overall scores (<i>p</i> < .05). However, the control group experienced declines in some measures. <b>Conclusion:</b> Functional training is a safe and effective intervention for improving physical function, cardiorespiratory fitness, and QoL in older women. The significant enhancements in physical and mental health highlight its value in promoting independence and well-being in aging populations. Future studies should explore its long-term benefits and scalability.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004251337063"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Significant Impacts of the Body-Mass Index, Blood Pressure, Blood Glucose, and Ankle-Brachial Index on Peripheral Neuropathy Risk in Indonesian With Type 2 Diabetes: A Cross-Sectional Study. 印度尼西亚2型糖尿病患者体重指数、血压、血糖和踝肱指数对周围神经病变风险的显著影响:一项横断面研究
Biological research for nursing Pub Date : 2025-04-22 DOI: 10.1177/10998004251336795
Siti Fadlilah, Vivi Leona Amelia, Cyruz P Tuppal, Hui-Chen Rita Chang, Ching Wen Chang, Chia Ling Lin, Hsiu Ting Tsai
{"title":"Significant Impacts of the Body-Mass Index, Blood Pressure, Blood Glucose, and Ankle-Brachial Index on Peripheral Neuropathy Risk in Indonesian With Type 2 Diabetes: A Cross-Sectional Study.","authors":"Siti Fadlilah, Vivi Leona Amelia, Cyruz P Tuppal, Hui-Chen Rita Chang, Ching Wen Chang, Chia Ling Lin, Hsiu Ting Tsai","doi":"10.1177/10998004251336795","DOIUrl":"https://doi.org/10.1177/10998004251336795","url":null,"abstract":"<p><p><b>Background:</b> Diabetic peripheral neuropathy is associated with morbidity and mortality in people with diabetes mellitus. <b>Aims:</b> In this study, we determined relationships of the body-mass index (BMI), systolic blood pressure, diastolic blood pressure, fasting blood glucose, HbA1c, and ankle-brachial index (ABI) with diabetic peripheral neuropathy risk. <b>Methods:</b> A cross-sectional study was conducted with 1088 Indonesians and data collected using self-reported questionnaires, laboratory examinations, and physical examinations. Instruments included a digital scale, height measurement device, digital sphygmomanometer, Doppler ultrasound, 10-g monofilament, and a 128-Hz tuning fork. Data analysis used the Chi-square test, Fisher Exact, and multiple logistic regression test with significance <i>p <</i> .05. <b>Results:</b> The BMI (<i>p <</i> .001), blood pressure (<i>p <</i> .001), ABI (<i>p <</i> .001), fasting blood glucose (<i>p =</i> .016), and HbA1c (<i>p <</i> .001) were significantly related to peripheral neuropathy risk. The conditions of obesity, hypertension, high ABI, high fasting blood glucose, and high HbA1c significantly increased the risk of peripheral neuropathy. Moreover, participants with ≥4 co-occurring abnormal levels of the BMI, systolic blood pressure, diastolic blood pressure, fasting blood glucose, HbA1c, and ABI had significantly synergistically increased risks of peripheral neuropathy, and the more abnormal conditions there were, the higher the risk of peripheral neuropathy. <b>Conclusions:</b> Abnormalities of the BMI, blood pressure, fasting blood glucose, HbA1c, and ABI significantly and synergistically increased the risk of peripheral neuropathy and can be considered predictors of peripheral neuropathy. Nurses are expected to be aware of these predictors so that they can immediately take appropriate steps if they encounter abnormal conditions by optimizing their role as educators.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004251336795"},"PeriodicalIF":0.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143999984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Considerations for the Use of Commercial Wearables to Assess Sleep and Rest-Activity Rhythms. 使用商业可穿戴设备评估睡眠和休息-活动节律的考虑。
Biological research for nursing Pub Date : 2025-04-22 DOI: 10.1177/10998004251337065
Mackenzie Morrison, Jemima Adisa, Olivia Trimiar, John Norfleet, Mathias Basner, Makayla L Cordoza
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