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Plant-Based Diets and Cardiovascular Disease in Older Adults: An Integrative Literature Review. 植物性饮食与老年人心血管疾病:综合文献综述》。
Biological research for nursing Pub Date : 2025-01-01 Epub Date: 2024-07-31 DOI: 10.1177/10998004241268287
Tricia R VanCleef, Amy Hutchens
{"title":"Plant-Based Diets and Cardiovascular Disease in Older Adults: An Integrative Literature Review.","authors":"Tricia R VanCleef, Amy Hutchens","doi":"10.1177/10998004241268287","DOIUrl":"10.1177/10998004241268287","url":null,"abstract":"<p><p>Cardiovascular disease (CVD) is the leading cause of mortality globally, disproportionately impacting older adults. Plant-based diets (PBDs) have emerged as a dietary strategy to mitigate CVD risk, characterized by foods derived from plants and minimal to no animal-derived foods. This integrative review assesses the effectiveness of PBDs for improving CVD risk factors in older adults. A search was conducted in CINAHL, PubMed, and Medline databases for studies of PBDs and CVD risk factors in individuals aged 65 years and older. Quality assessment was performed using the Mixed Methods Appraisal Tool (MMAT). Seventeen publications were analyzed, 7 experimental and 10 non-experimental. All studies showed at least one positive association between PBDs and cardiovascular health in older adults. Findings highlighted significant associations between PBD adherence and reductions in key CVD risk factors, such as low-density lipoprotein cholesterol (LDL-C), blood pressure, and body mass index (BMI), alongside potential benefits in reducing coronary artery calcium and enhancing endothelial function and serum isoflavone concentrations. There is evidence for the potential of PBDs as an effective dietary strategy to prevent the onset and progression of CVD in older adults and reduce the risk of CVD mortality. This review indicates the need for further research. Larger randomized control trials focused on older adults may strengthen the evidence base and guide healthcare recommendations. PBDs should be considered as a part of holistic CVD prevention and management strategies for older adults, encouraging dietary patterns that are rich in fruits, vegetables, legumes, beans, nuts, seeds, and whole grains.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"109-126"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141857347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effects of Aquatic Exercise Training on Functional and Hemodynamic Responses in Patients With Heart Failure: A Systematic Review and Meta-Analysis. 水上运动训练对心力衰竭患者功能和血流动力学反应的影响:系统回顾与元分析》。
Biological research for nursing Pub Date : 2025-01-01 Epub Date: 2024-06-21 DOI: 10.1177/10998004241263943
Yaser Alikhajeh, Roghayyeh Afroundeh, Gholam Rasul Mohammad Rahimi, Baktash Bayani
{"title":"The Effects of Aquatic Exercise Training on Functional and Hemodynamic Responses in Patients With Heart Failure: A Systematic Review and Meta-Analysis.","authors":"Yaser Alikhajeh, Roghayyeh Afroundeh, Gholam Rasul Mohammad Rahimi, Baktash Bayani","doi":"10.1177/10998004241263943","DOIUrl":"10.1177/10998004241263943","url":null,"abstract":"<p><p><b>Objective:</b> This study aimed to investigate the impacts of water exercise training on functional and hemodynamic responses in HF patients. <b>Methods:</b> A systematic review and meta-analysis were conducted until February 15, 2024, using multiple databases. Mean difference (MD) with corresponding 95% confidence intervals (CIs) were calculated. <b>Results:</b> Sixteen studies, comprising 349 participants with HF, were included. Water exercise led to enhancements in peak VO<sub>2</sub> (MD, 2.85 mL/kg/min; 95% CI, 1.89 to 3.80; <i>p</i> < .00001) and resting heart rate (MD, -4.16 bm; 95% CI, -6.85 to -1.46; <i>p</i> = .002) compared to no exercising controls. Water plus land exercise reduced resting heart rate (MD, -1.41 bm; 95% CI, -2.13 to -0.69; <i>p</i> = .0001) compared to land exercise alone. Furthermore, acute water exercises decreased resting heart rate (MD, -3.85 bm; 95% CI, -6.49 to -1.21; <i>p</i> = .004) and increased stroke volume (MD, 14.68 mL/beat; 95% CI, 8.57 to 20.79; <i>p</i> < .00001) and cardiac output (MD, 0.5 L/min; 95% CI, 0.27 to 0.73; <i>p</i> < .00001) compared to baseline. <b>Conclusion:</b> These findings suggest that water exercise holds promise as an effective intervention for enhancing functional capacity and hemodynamic parameters in individuals with HF, highlighting the importance of further research to optimize its implementation and elucidate long-term benefits.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"127-141"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141433654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aerobic Training and Ointment Effect on  range of motion, von Willebrand factor, vascular endothelial factor and Femoral Artery Hemodynamics in Joint Contracture: A Rat Model. 有氧训练和药膏对关节挛缩症患者活动范围、von Willebrand因子、血管内皮因子和股动脉血流动力学的影响:大鼠模型。
Biological research for nursing Pub Date : 2025-01-01 Epub Date: 2024-08-14 DOI: 10.1177/10998004241274290
Palida Maimaiti, Jiaojiao Shu, Tianyu Miao, Nuerbiya Keqike, Asiguli Tuersun, Ruiqi Yang, Ningning Wang
{"title":"Aerobic Training and Ointment Effect on  range of motion, von Willebrand factor, vascular endothelial factor and Femoral Artery Hemodynamics in Joint Contracture: A Rat Model.","authors":"Palida Maimaiti, Jiaojiao Shu, Tianyu Miao, Nuerbiya Keqike, Asiguli Tuersun, Ruiqi Yang, Ningning Wang","doi":"10.1177/10998004241274290","DOIUrl":"10.1177/10998004241274290","url":null,"abstract":"<p><strong>Objective: </strong>Using a rat model, we investigated the effect of multidisciplinary rehabilitation, including aerobic training and ointment, on the ROM, vWF, VEGF content, and femoral artery hemodynamics in rats with joint contracture.</p><p><strong>Methods: </strong>A total of 44 Wistar rats were divided into the normal control group (NC, eight rats) and the experimental group (EG). A joint contracture model was established for the rats in the EG group by an external fixator. After fixator removal, 32 rats are further divided into the MC, SC, RE, and SR groups (<i>n</i> = 8). Before and after the 42 day intervention, the ROM, vWF, VEGF, PS, ED, and RI were measured using X-ray imaging, ELISA, and color Doppler ultrasound, respectively.</p><p><strong>Results: </strong>After fixator removal, ROM for EG group was lower than that of the NC group (<i>p</i> < .01). After the intervention, ROM for the SR, RE, and SC groups was improved. The ROM for the SR group reached a similar value for NC group. vWF and VEGF levels in SR group were lower than in the MC, SC, and RE groups (<i>p</i> < .05), and had a similar value to the NC groups. PS value for SR and RE groups was higher than the MC and SC groups. The RI value for SR group was higher than that of NC and MC groups.</p><p><strong>Conclusion: </strong>Multidisciplinary rehabilitation used in this study can treat joint contracture synergistically. It improves the ROM of the joint, reduces the content of vWF and VEGF, and improves the femoral artery hemodynamics.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"17-27"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141984158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IL-16 Mediates the Effect of Circulating Metabolites on Postmenopausal Osteoporosis: A Two-Step, Multivariable Mendelian Randomization Study. IL-16 介导循环代谢物对绝经后骨质疏松症的影响:一项两步多变量孟德尔随机研究
Biological research for nursing Pub Date : 2025-01-01 Epub Date: 2024-08-30 DOI: 10.1177/10998004241279934
Yi Chen, Hefang Xiao, Fei Teng, Ao Yang, Fei Yang, Changshun Chen, Rongjin Chen, Bin Geng, Yayi Xia
{"title":"IL-16 Mediates the Effect of Circulating Metabolites on Postmenopausal Osteoporosis: A Two-Step, Multivariable Mendelian Randomization Study.","authors":"Yi Chen, Hefang Xiao, Fei Teng, Ao Yang, Fei Yang, Changshun Chen, Rongjin Chen, Bin Geng, Yayi Xia","doi":"10.1177/10998004241279934","DOIUrl":"10.1177/10998004241279934","url":null,"abstract":"<p><p><b>Objectives:</b> This study aimed to explore the relationship between circulating metabolites and postmenopausal osteoporosis (PMOP) and to assess the mediating role of inflammatory factors. <b>Methods:</b> Utilizing summary-level data from genome-wide association studies (GWAS) and employing a Mendelian Randomization approach, a two-sample MR analysis was conducted to assess the relationship between circulating metabolites and PMOP. Additionally, a two-step MR was used to quantify the mediating impact of inflammatory factors on the effect of circulating metabolites on PMOP. <b>Results:</b> The results revealed a significant association between certain metabolites and the risk of PMOP, notably the ratio of free cholesterol to total lipids in very large VLDL particles (OR: 1.399, 95% CI: 1.002-1.954, <i>p</i> = 0.048) and IL-16 (OR: 0.773, 95% CI: 0.608-0.983, <i>p</i> = 0.036). IL-16 was found to partially mediate the impact of circulating metabolites on PMOP, with a mediation effect of 10.4%. <b>Conclusion:</b> This study underscores the crucial role of circulating metabolites and inflammatory factors in PMOP pathogenesis. A causal relationship between circulating metabolites and PMOP was established, with IL-16 mediating some effects. These findings hold promise for clinical applications in early detection, personalized medicine, and the identification of therapeutic targets for PMOP.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"91-100"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142115866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Childhood Adversity and Telomere Length.
Biological research for nursing Pub Date : 2024-12-17 DOI: 10.1177/10998004241309368
Rita H Pickler, Jodi L Ford, Alai Tan, Christopher Browning, Jake Tarrence, Darlene A Kertes
{"title":"Childhood Adversity and Telomere Length.","authors":"Rita H Pickler, Jodi L Ford, Alai Tan, Christopher Browning, Jake Tarrence, Darlene A Kertes","doi":"10.1177/10998004241309368","DOIUrl":"https://doi.org/10.1177/10998004241309368","url":null,"abstract":"<p><p><b>Purpose:</b> Exposure to adversity during childhood and adolescence is associated with numerous health conditions in adulthood; telomere shortening may be a mechanism through which adversity contributes to poor outcomes. We studied three areas of adversity (parent relational instability, child household instability, and financial instability) occurring during three epochs across childhood and adolescence and their associations with telomere length during adolescence. <b>Methods:</b> Data were obtained from the first wave of a longitudinal cohort study of youth aged 11-17 and their primary caregiver. Caregivers completed demographic and adversity questionnaires; youth provided a saliva sample for DNA extraction for telomere analysis. <b>Results:</b> Of 879 youth, over half experienced some adversity. More than one third experienced parent relational instability in each age epoch, with nearly a quarter experiencing parent relational instability in all age epochs. Youth experienced a similar pattern of financial instability but lower rates of child household instability. Youth experiencing parent relational instability at two or three epochs had shorter telomeres compared to those without any parent relational instability (<i>p</i> < .004). Youth who experienced child household instability in two age epochs had shorter telomeres (<i>p</i> = .003) and youth who experienced financial instability across all three epochs had shorter telomeres (<i>p</i> = .013) compared to youth without these adversities. <b>Conclusion:</b> Continuing exposure to adversity in early childhood may be more likely to affect telomere length. Research is needed to further determine adversities exerting the most effect and to understand if early telomere shortening has long term health effects.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004241309368"},"PeriodicalIF":0.0,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetic Association of Chronic Pains and Analgesics With Telomere Length: A Mendelian Randomization Study.
Biological research for nursing Pub Date : 2024-12-01 DOI: 10.1177/10998004241303536
Jiahe Chen, Haotian Liu, Yulin Pang, Yubo Wang, Ziqi Ren, Jianli Liu, Yang Nan, Dan Liu
{"title":"Genetic Association of Chronic Pains and Analgesics With Telomere Length: A Mendelian Randomization Study.","authors":"Jiahe Chen, Haotian Liu, Yulin Pang, Yubo Wang, Ziqi Ren, Jianli Liu, Yang Nan, Dan Liu","doi":"10.1177/10998004241303536","DOIUrl":"https://doi.org/10.1177/10998004241303536","url":null,"abstract":"<p><p><b>Objective:</b> The aim of this study was to explore the causal relationships between chronic pains (back pain, facial pain, general pain, headaches, knee pain, hip pain, neck/shoulder pain, stomach/abdominal pain) and analgesics (codeine, diclofenac, ibuprofen, morphine, paracetamol, tramadol) with telomere length using Mendelian randomization methods. <b>Methods:</b> In the study, various statistical methods including inverse variance weighted (IVW), Mendelian Randomization-Egger, weighted median, simple mode, and weighted mode were used to investigate the relationships between chronic pains, analgesics, and telomere length. Heterogeneity and pleiotropy tests were conducted to ensure the accuracy of the results. <b>Results:</b> The results of the IVW analysis revealed positive causal relationships between hip pain (odds ratio (OR): 1.145; 95% confidence interval (CI): 1.021-1.285; <i>p</i> = .020), and stomach/abdominal pain (OR: 1.100; 95% CI: 1.008-1.200; <i>p</i> = 0.033) with telomere length. Use of tramadol (OR: 0.074; 95% CI: 0.009-0.605; <i>p</i> = 0.015) had a negative causal relationships with telomere length. <b>Conclusion:</b> This study found positive associations between hip pain and stomach/abdominal pain with telomere length, and a negative association between tramadol and telomere length. However, no significant causal relationships were found with other types of chronic pains and analgesics. This could help develop healthier chronic pain treatments, avoiding the abuse of analgesics.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004241303536"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetic Evidence of Obesity-Induced Chronic Wounds Mediated by Inflammatory Biomarkers. 由炎症生物标志物介导的肥胖诱发慢性伤口的遗传证据
Biological research for nursing Pub Date : 2024-11-20 DOI: 10.1177/10998004241299375
Hai Xu, Sheyuan Ding, Yu Tong, Qiong Zhang
{"title":"Genetic Evidence of Obesity-Induced Chronic Wounds Mediated by Inflammatory Biomarkers.","authors":"Hai Xu, Sheyuan Ding, Yu Tong, Qiong Zhang","doi":"10.1177/10998004241299375","DOIUrl":"https://doi.org/10.1177/10998004241299375","url":null,"abstract":"<p><p><b>Background:</b> Obese patients are increasingly recognized as being at higher risk for skin diseases, particularly chronic wounds. While the exact mechanisms remain unclear, obesity is suspected to influence the development of chronic injuries via inflammatory biomarkers. Single nucleotide polymorphisms (SNPs) may further influence gene expression, protein function, and levels of inflammatory biomarkers through various mechanisms, thereby modulating inflammatory responses that contribute to wound pathogenesis. <b>Methods:</b> A two-sample two-step Mendelian Randomization (MR) was employed to explore the causal relationship between obesity and chronic wounds, focusing on the mediating role of inflammatory biomarkers. SNPs were used as instrumental variables (IVs) to infer causality. Obesity-related genetic data were sourced from the UK Biobank and GIANT consortium. Genome-wide association studies provided data on 92 inflammatory biomarkers, involving 14,824 and 575,531 individuals. Pressure injuries, lower limb venous ulcers, and diabetic foot ulcer data were obtained from FinnGen R10 and the Pan-UK Biobank. <b>Results:</b> Obesity significantly increased the risk of pressure injuries, lower limb venous ulcers, and diabetic foot ulcers. CCL19, hGDNF, IL-12B, and TNFRSF9 were identified as mediators in obesity-induced lower limb venous ulcers. <b>Conclusion:</b> This study provides genetic evidence that obesity leads to lower limb venous ulcers via inflammatory biomarkers, suggesting potential therapeutic targets for intervention.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004241299375"},"PeriodicalIF":0.0,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delayed Lactogenesis II in High-Risk Pregnancies: What Should We Care. 高危妊娠中的乳汁生成延迟 II:我们应该注意什么?
Biological research for nursing Pub Date : 2024-11-13 DOI: 10.1177/10998004241300477
Qianqian Liu, Hanxiang Lin
{"title":"Delayed Lactogenesis II in High-Risk Pregnancies: What Should We Care.","authors":"Qianqian Liu, Hanxiang Lin","doi":"10.1177/10998004241300477","DOIUrl":"https://doi.org/10.1177/10998004241300477","url":null,"abstract":"<p><p><b>Background:</b> The timely initiation of lactogenesis II is crucial for postpartum women, with delays having significant clinical implications. This study aimed to evaluate the determinants of delayed lactogenesis II (DOL II) in high-risk pregnant women to guide clinical interventions and postnatal care protocols. <b>Methods:</b> We conducted a study involving high-risk pregnant women who gave birth and were admitted to our hospital''s obstetric intensive care unit for postpartum surveillance and treatment from February 1, 2023, to April 30, 2024. We utilized Pearson correlation analysis and logistic regression to determine factors linked to DOL II. <b>Results:</b> Our study included 206 high-risk pregnant women, with 85 (41.26%) experiencing DOL II. Pearson correlation analysis indicated strong associations between DOL II and maternal age (r = 0.452), gestational hypertension (r = 0.514), gestational diabetes (r = 0.487), and delayed colostrum secretion (r = 0.506), all statistically significant (<i>p <</i> 0.05). Logistic regression analysis identified age 35 years or older (OR = 2.115, 95%CI: 1.785-2.466), gestational hypertension (OR = 2.404, 95%CI: 2.125-3.107), gestational diabetes (OR = 2.556, 95%CI: 2.008-2.879), and colostrum secretion later than one hour postpartum (OR = 3.126, 95%CI: 2.682-3.605) as independent risk factors for DOL II, all with <i>p <</i> 0.05. <b>Conclusions:</b> The incidence of DOL II is significantly elevated in high-risk pregnant women, especially those aged 35 or older, those with gestational diabetes and hypertension, and those who delay the initiation of breastfeeding. It is imperative that clinical practices prioritize enhanced prenatal care and health education, robust lactation support, and improved lactation awareness among postpartum women to reduce the prevalence of DOL II.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004241300477"},"PeriodicalIF":0.0,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex-Specific Impact of Serum Calcium Levels on Acute Coronary Syndrome Risk: A 19-Year Cohort Study in Korea. 血清钙水平对急性冠状动脉综合征风险的性别特异性影响:韩国一项为期 19 年的队列研究。
Biological research for nursing Pub Date : 2024-11-07 DOI: 10.1177/10998004241295360
Eujene Jung, Dong Ki Kim, Seok Jin Ryu, Hyun Ho Ryu
{"title":"Sex-Specific Impact of Serum Calcium Levels on Acute Coronary Syndrome Risk: A 19-Year Cohort Study in Korea.","authors":"Eujene Jung, Dong Ki Kim, Seok Jin Ryu, Hyun Ho Ryu","doi":"10.1177/10998004241295360","DOIUrl":"https://doi.org/10.1177/10998004241295360","url":null,"abstract":"<p><p><b>Background:</b> This study aims to investigate the association between serum calcium levels and acute coronary syndrome (ACS) risk, examining whether this relationship differs by sex, given the known differences in calcium metabolism and hormonal influences between males and females. <b>Methods:</b> Utilizing the Korean Genome Epidemiology Study (KoGES) prospective cohort data, our primary exposure variables were serum calcium level and sex. The incidence of ACS served as the main outcome of interest. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox regression analysis. An interaction analysis was conducted to assess the interaction effect of calcium level and sex on ACS incidence. <b>Results:</b> After adjusting for confounding variables, high calcium intake did not significantly increase ACS incidence, with a hazard ratio (HR) of 1.07 (95% CI: 0.90-1.26). There was also no significant difference in ACS risk between females and males (HR: 0.81, 95% CI: 0.61-1.04). However, interaction effect analysis revealed that higher calcium levels were associated with an increased risk of ACS only in females (HR: 1.24, 95% CI: 1.07-1.58), whereas the association in males was not statistically significant (HR: 0.90, 95% CI: 0.71-1.15). <b>Conclusion:</b> Our study results indicate that elevated serum calcium levels alone did not independently increase the risk of ACS; however, high serum calcium levels were associated with an increased risk of ACS in females but not in males, underscoring the importance of sex-specific factors in assessing and managing ACS risk and highlighting the necessity for personalized medical approaches to improve cardiovascular health outcomes for women.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004241295360"},"PeriodicalIF":0.0,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142592390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Six Weeks to Wellness: The Role of Breathing Exercises Based on Motor Development Pattern in Improving Fitness and Quality of Life in Overweight Elderly Women. 六周健康:基于运动发展模式的呼吸练习在改善超重老年妇女的体能和生活质量中的作用》。
Biological research for nursing Pub Date : 2024-10-29 DOI: 10.1177/10998004241297403
Fatemeh Mohammad Rahimi, Mehdi Sohrabi, Alireza Saberi Kakhki, Nasser Mohammad Rahimi
{"title":"Six Weeks to Wellness: The Role of Breathing Exercises Based on Motor Development Pattern in Improving Fitness and Quality of Life in Overweight Elderly Women.","authors":"Fatemeh Mohammad Rahimi, Mehdi Sohrabi, Alireza Saberi Kakhki, Nasser Mohammad Rahimi","doi":"10.1177/10998004241297403","DOIUrl":"10.1177/10998004241297403","url":null,"abstract":"<p><p><b>Background:</b> Being overweight is a major global health epidemic of the 20th and 21st centuries, which can affect the movement system function of older adult women. This study evaluated the effects of a breathing exercise based on motor development patterns on functional fitness and quality of life in overweight older adult women. <b>Methods:</b> A randomized controlled trial was conducted with 40 community-dwelling women aged 65-75. Participants were randomly assigned to an intervention group, which completed a 6-week breathing exercise program (three supervised and three home-based sessions per week), or a control group, which maintained usual routines. Outcome measures included cardiovascular fitness, upper and lower body flexibility, muscle strength, dynamic balance, and quality of life, assessed at baseline and post-intervention. <b>Results:</b> The intervention group showed significant improvements in cardiovascular fitness (<i>p <</i> .001, ES = 0.652), upper body flexibility (<i>p <</i> .001, ES = 0.652), lower body flexibility (<i>p <</i> .001, ES = 0.538), upper body strength (<i>p <</i> .001, ES = 0.538), lower body strength (<i>p <</i> .001, ES = 0.538), and dynamic balance (<i>p <</i> .001, ES = 0.475) compared to the control group. Quality of life also significantly improved in the intervention group (<i>p <</i> .001, ES = 0.475). <b>Conclusion:</b> Breathing exercises based on motor development patterns significantly enhance functional fitness and quality of life in overweight older adult women. Incorporating these exercises into regular physical activity routines may promote health and independence in older adults. Further research should explore long-term benefits and optimal exercise parameters for older adults.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004241297403"},"PeriodicalIF":0.0,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142523834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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