Biological research for nursing最新文献

{"title":"The Association Between the Neutrophil-To-lymphocyte Ratio and Health-related Behaviors and Factors in Rural Adults With and Without Cardiometabolic Disease.","authors":"Hsiang-Ting Lu, Yu-Chih Lin, Tung-Jung Huang, Mei-Yen Chen","doi":"10.1177/10998004251336478","DOIUrl":"10.1177/10998004251336478","url":null,"abstract":"<p><p>BackgroundComplete blood count (CBC) is a commonly used and cost-effective blood test in health screenings; however, its potential as a biomarker for early detection of chronic diseases remains underutilized. Previous studies have shown that the neutrophil-to-lymphocyte ratio (NLR) is associated with systemic inflammation and is correlated with cardiometabolic diseases (CMDs). Unhealthy lifestyles can trigger inflammatory responses and contribute to the progression of CMDs. This study aimed to explore the association between NLR levels, cardiometabolic risks, and health-related behaviors.MethodsA community-based, cross-sectional study was conducted in collaboration with a local hospital as part of an annual health screening for rural adults. The study outcomes included CMDs, health-related behaviors, and NLR levels. A multivariable quantile regression model, adjusted for confounding factors, was used to identify factors associated with NLR levels.ResultsA total of 11,220 participants were enrolled. CMDs prevalence was 25.8%, with hypertension and diabetes being most common. Nearly half of participants reported insufficient exercise, low water intake, and inadequate oral hygiene. Higher NLR was significantly associated with CMDs (<i>p</i> for trend <0.001). Older age (<i>p</i> < .01) and living alone (<i>p</i> < .01) were linked to higher NLR, while adequate water intake (<i>p</i> < .05) and regular exercise (<i>p</i> < .01) were associated with lower NLR levels.ConclusionsRural adults demonstrated a high prevalence of CMDs and inadequate health-related behaviors, which were associated with elevated NLR levels. Implementing NLR-guided lifestyle modifications and tailored health promotion programs may serve as innovative strategies to mitigate the progression of CMDs.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"535-543"},"PeriodicalIF":2.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Functional Training on Physical Function, Cardiorespiratory Fitness, and Quality of Life in Older Women: A 6-Week Randomized Controlled Trial.","authors":"Akram Dashti, Nasser Mohammad Rahimi, Amin Azimkhani","doi":"10.1177/10998004251337063","DOIUrl":"10.1177/10998004251337063","url":null,"abstract":"<p><p><b>Background:</b> Functional training is increasingly recognized for its potential to improve physical function and quality of life (QoL) in older adults. This randomized controlled trial examined the effects of a six-week functional training program on physical function, cardiorespiratory fitness, and QoL in older women. <b>Methods:</b> Fifty older women (mean age: 63.5 ± 3.7 years) were randomly assigned to a functional training group (<i>n</i> = 25) or a control group (<i>n</i> = 25). The intervention group participated in a six-week functional training program (six sessions per week), while the control group maintained usual daily activities. Outcomes included dynamic balance (TUG test), flexibility, muscle strength, walking speed, cardiorespiratory fitness (two-minute step test), and QoL. <b>Results:</b> Functional training significantly improved dynamic balance, lower body flexibility, lower body strength, walking speed, and aerobic endurance (<i>p</i> < .05 for all). QoL significantly increased in the functional training group across all domains, as well as overall scores (<i>p</i> < .05). However, the control group experienced declines in some measures. <b>Conclusion:</b> Functional training is a safe and effective intervention for improving physical function, cardiorespiratory fitness, and QoL in older women. The significant enhancements in physical and mental health highlight its value in promoting independence and well-being in aging populations. Future studies should explore its long-term benefits and scalability.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"570-580"},"PeriodicalIF":2.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation Between Glycemic Variability in Patients With Intracerebral Hemorrhage and Neurological Deterioration.","authors":"Lichun Lu, Xiangyi Yin, Chen Wang, Xianlan Meng, Gongbo Li, Wenyu Zhu","doi":"10.1177/10998004251344888","DOIUrl":"10.1177/10998004251344888","url":null,"abstract":"<p><p><b>Background:</b> Glycemic variability and its management hold significant prognostic implications in clinical practice for patient outcomes. The aim of this study is to analyze the correlation between glycemic variability and the deterioration of neurological function in patients with intracerebral hemorrhage (ICH), to provide evidence-based support for the treatment and care of clinical ICH patients. <b>Methods:</b> Patients with ICH admitted to our hospital between January 2022 and August 2024 were subjected to the National Institutes of Health Stroke Scale (NIHSS) scoring upon admission and discharge. A comparative analysis of baseline characteristics and glycemic variability parameters was conducted. <b>Results:</b> A total of 156 patients with ICH were included. The incidence of neurological deterioration in ICH patients was 30.8%. Correlation analysis revealed significant associations between age (r = 0.602), mean glucose levels (r = 0.623), Time in Range (TIR) (r = 0.589), Mean Amplitude of Glycemic Excursions (MAGE) (r = 0.608), and Large Amplitude of Glycemic Excursions (LAGE) (r = 0.634) with the occurrence of neurological deterioration. Logistic regression analysis identified age (OR = 2.512, 95%CI: 1.924-3.006), mean glucose (OR = 2.743, 95%CI: 2.101-3.286), TIR (OR = 3.204, 95%CI: 2.985-3.607), MAGE (OR = 3.029, 95%CI: 2.601-3.748), and LAGE (OR = 2.768, 95%CI: 2.245-3.103) as significant predictors of neurological deterioration in ICH patients. <b>Conclusion:</b> This finding underscores the critical importance of considering both chronological age and glycemic control metrics in the prognostic evaluation of ICH patients. Integrating these factors into clinical assessments may enhance the accuracy of predicting patient outcomes and guide tailored therapeutic strategies.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"612-619"},"PeriodicalIF":2.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144113040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pain Resilience and Chronic Low Back Pain Outcomes: The Mediating Role of Pace of Biological Aging.","authors":"Kiari Kinnie Davis, Khalid W Freij, Fiona B A T Agbor, Asia M Wiggins, Tammie L Quinn, Demario S Overstreet, Shivraj S Grewal, Robert E Sorge, Burel R Goodin, Edwin N Aroke","doi":"10.1177/10998004251345491","DOIUrl":"10.1177/10998004251345491","url":null,"abstract":"<p><p>In this study, we aimed to investigate if the pace of biological aging serves as a critical mediator in the relationship between chronic pain resilience and chronic low back pain intensity and disability. Two hundred seven community-dwelling non-Hispanic Black (NHB) and non-Hispanic White (NHW) adults completed the Pain Resilience Scale (PRS) and Graded Chronic Pain Scale (GCPS). Blood genomic DNA was sequenced using Illumina's MethylationEPIC, and the pace of biological aging estimated using the DunedinPACE (the Dunedin Pace of Aging Calculated from the Epigenome) algorithm. In bivariate correlations, DunedinPACE significantly correlated with pain intensity (r = 0.40), and disability (r = 0.39), at <i>p <</i> .05. Pain resilience negatively correlated with pain intensity (rs = -0.22), pain disability (rs = -0.30), and DunedinPACE (r = -0.11). After controlling for chronological age, sex, race, and BMI, mediation analyses revealed a significant indirect association of pain resilience on pain intensity through the pace of biological aging (β = -0.66 (SE); Boot 95% CI [-1.06, -0.25]). Similarly, DunedinPACE partially mediated the relationship between resilience and pain disability (β = -0.82; 95% CI, [-1.20 to -0.44]). We found that higher levels of resilience correlate with a slower pace of biological aging, which in turn correlates with better pain outcomes. The pace of biological aging emerged as an important potential target for future interventions studies for pain management.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"620-629"},"PeriodicalIF":2.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>APOE</i> ε4 Allele and Methylation Patterns Linked to Cardiovascular Outcomes in Women With Breast Cancer.","authors":"Emily K Mewborn, Myeong-Ga Cho, Kirk I Erickson, Catherine M Bender, Yvette Conley","doi":"10.1177/10998004251385243","DOIUrl":"https://doi.org/10.1177/10998004251385243","url":null,"abstract":"<p><p>DNA methylation affects gene expression. While the Apolipoprotein E (<i>APOE</i>) genotype impacts cardiovascular risk, <i>APOE</i> methylation impact remains unknown, particularly in women with breast cancer (BC). This study explored associations of <i>APOE</i> methylation with hypertension history and cardiovascular fitness (CVF) and whether <i>APOE</i> genotype and methylation moderate exercise effects over 6 months. This study leveraged data from a 6-month exercise randomized clinical trial in postmenopausal women with BC. Using peripheral blood, methylation M-values (Illumina Infinium Methylation EPIC Beadchip) and 13 CpG sites within and 2kb 5' and 3' to <i>APOE</i> were abstracted post data quality checks. Outcome variables: self-reported hypertension and CVF (peak oxygen consumed per kilogram per minute [VO₂max/kg/min] and peak metabolic equivalents [METs] through graded exercise testing). Participants completed 150 min/week of aerobic exercise or usual care for 6 months. Logistic and linear regression examined associations between CpG M-values and hypertension, VO₂max/kg/min and METs. Baseline M-value and <i>APOE</i> genotype were interaction terms for longitudinal analyses. This study included 102 women (Mean = 62 yrs). <i>APOE</i>ε4 carriers had increased methylation of cg06750524 (<i>p =</i> 0.04) and cg19514613 (<i>p =</i> 0.03), but lower methylation of cg21879725 (<i>p =</i> 0.04). Increased cg06750524 methylation was associated with higher hypertension odds (<i>p =</i> 0.022, OR = 2.813) and lower VO₂max/kg/min and METs (<i>p =</i> 0.005). Increased cg05501958 methylation (M = 4.539, SD = 0.17) was associated with lower hypertension odds (<i>p =</i> 0.02, OR = 0.035) and higher VO₂max/kg/min and METs (<i>p =</i> 0.022). Neither <i>APOE ε4</i> nor baseline methylation moderated exercise effects. <i>APOE</i> methylation, differentially by ε4 carriage, may impact cardiovascular outcomes and serve as a biomarker of risk in women with BC.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004251385243"},"PeriodicalIF":2.1,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145202398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Traditional Chinese Exercise on Menopausal Symptoms, Bone Health and Mental Health in Perimenopausal and Postmenopausal Women: A Systematic Review and Meta-Analysis.","authors":"Yuanxia Liu, Yapeng He, Qi Zhang, Qunfeng Lu","doi":"10.1177/10998004251377748","DOIUrl":"https://doi.org/10.1177/10998004251377748","url":null,"abstract":"<p><p><b>Background:</b> Perimenopausal and postmenopausal women commonly experience vasomotor symptoms, bone loss, and mental health challenges that diminish quality of life (QoL). Although Traditional Chinese Exercise (TCE) has shown benefits in alleviating certain menopausal symptoms, its overall effects on health-related outcomes remain controversial. <b>Objectives:</b> This study aimed to systematically analyze the effects of TCE on menopausal symptoms, bone health, and mental health in perimenopausal and postmenopausal women. <b>Methods:</b> A systematic search was conducted across 7 databases through April 2025 for randomized controlled trials (RCTs) investigating the effects of TCE in perimenopausal and postmenopausal women. Risk of bias was assessed using the Cochrane Risk of Bias Tool 2 (RoB 2). Stata 17.0 was used for meta-analysis, with pooled outcomes reported as standardized or mean differences (SMD/MD) with 95% confidence intervals (CIs). <b>Results:</b> Twelve RCTs involving 1,023 participants were included. Meta-analysis showed that TCE significantly reduced menopausal symptoms (SMD = -0.82, 95% CI: -1.41 to -0.22), and depression (SMD = -1.73, 95% CI: -2.49 to -0.98). TCE also improved spine BMD (MD = 0.05, 95% CI: 0.02 to 0.08). For upper limb, thigh, pelvis, trunk, and whole-body BMD, effects remained uncertain due to the limited number of studies. Three studies assessed QoL, and pooled results showed no significant improvement in physical (MD = 4.52, 95% CI: -2.93 to 11.97) or mental component scores (MD = 3.28, 95% CI: -3.67 to 10.23). <b>Conclusions:</b> TCE appears to be an effective intervention for menopausal symptoms, spine BMD, and depression. However, its effects on QoL and other skeletal sites remain inconclusive. Larger, high-quality RCTs are warranted to clarify optimal protocols and long-term benefits.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004251377748"},"PeriodicalIF":2.1,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145093247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Defining Genetic Ancestry: Implications for Nurses.","authors":"Alexis Jimenez, Karla Lindquist, Kayla D Longoria, Benjamin M Stroebel, Bradley E Aouizerat, Elena Flowers","doi":"10.1177/10998004251374146","DOIUrl":"https://doi.org/10.1177/10998004251374146","url":null,"abstract":"<p><p><b>Introduction:</b> This paper provides an overview of methods for measuring genetic ancestry, specifically focusing on applications for nurses engaged in research. We describe methods and current tools widely implemented by the research community to introduce nurses who conduct research in the landscape of measuring genetic admixture for individuals and genetic substructure for populations. The intended impact of this paper is to enhance awareness and understanding of the importance of measuring genetic ancestry to control for latent confounding in genetic association studies. <b>Summary of best practices:</b> Measurement of genetic ancestry can prevent confounding in genetic association studies. <b>Conclusions:</b> Nurses approach health from a holistic perspective that includes information about individual, environmental, and social factors. This framework necessitates consideration of individual genetic characteristics and social identity and position. This paper serves as a primer on concepts related to genetic ancestry, including ancestry informative markers, reference populations, and statistical approaches, that nurses engaged in research may incorporate into their study design and implementation.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004251374146"},"PeriodicalIF":2.1,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144982431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex-Specific Factors Influencing GrimAge Acceleration in Middle-Aged Korean Adults.","authors":"Seungkyu Kim, Jongmin Park","doi":"10.1177/10998004251370671","DOIUrl":"https://doi.org/10.1177/10998004251370671","url":null,"abstract":"<p><p><b>Background</b>: Middle-aged adults experience degenerative aging-related changes, often differing by sex. Research identifying sex-specific factors contributing to biological aging among middle-aged adults remains limited. This study aimed to identify sex-specific factors influencing GrimAge acceleration (GrimAA), a DNA methylation-based estimator of biological aging, among middle-aged Korean adults. <b>Methods</b>: Data were derived from the Korean Genome and Epidemiology Study (KoGES) cohort involving 686 middle-aged adults (422 men and 264 women). GrimAA was calculated from DNA methylation data using the GrimAge epigenetic clock. Demographic, lifestyle, clinical, and psychosocial stress variables were assessed, and sex-specific factors influencing GrimAA were identified through hierarchical multiple regression models. <b>Results</b>: In men, higher GrimAA was significantly associated with current smoking, current drinking, physical inactivity, and elevated Hs-CRP or HbA1C levels, whereas among women, early menopause (<50 years) emerged as a notable factor related to increased GrimAA. Hierarchical regression analyses revealed that chronological age, current smoking, and Hs-CRP were robust predictors of GrimAA in men, whereas GrimAA in women was significantly predicted by current smoking and Hs-CRP. <b>Conclusion</b>: Sex differences in GrimAA may result from the interplay of lifestyle behaviors, inflammatory biomarkers, and hormonal factors. Targeted interventions addressing these sex-specific determinants could be effective strategies to mitigate biological aging acceleration among middle-aged adults.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004251370671"},"PeriodicalIF":2.1,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144982420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying the Ongoing Risk and the Critical Time Point of Cardiovascular Diseases in Women With Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis of Cohort Studies.","authors":"Zixuan Wei, Tingting Yan, Yi Wu, Linping Shang, Shifan Han, Mingzi Li","doi":"10.1177/10998004251366590","DOIUrl":"https://doi.org/10.1177/10998004251366590","url":null,"abstract":"<p><p>This study assessed the risk of cardiovascular diseases (CVD) at various stages in women with gestational diabetes mellitus (GDM) and aimed to identify critical time points when the risk increases. Fifteen cohort studies including a total of 7,515,168 pregnant women were analyzed, among whom 429,564 had GDM and 13,773 developed CVD. Participants were grouped based on follow-up periods of approximately 5, 10, 15, and 25 years. Using random effects models, pooled hazard ratios (HR) with 95% confidence intervals (CI) were calculated. Within five years of diagnosis, women with GDM had a 19% higher risk of CVD (HR 1.19, 95% CI 1.11-1.27) compared to those without GDM, rising to 78% by the tenth year (HR 1.78, 95% CI 1.67-1.89). Long-term follow-up showed risk increases of 31% at 15 years (HR 1.31, 95% CI 1.28-1.35) and 26% at 25 years (HR 1.26, 95% CI 1.16-1.38). Overall, women with GDM had a 35% higher risk of developing CVD than those without (HR 1.35, 95% CI 1.32-1.38). These findings highlight that GDM significantly elevates the risk of cardiovascular diseases, particularly within ten years after diagnosis, emphasizing the need for timely intervention and ongoing monitoring to reduce cardiovascular risk in affected women.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004251366590"},"PeriodicalIF":2.1,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144801225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lifestyle and Genetic Factors Associated With Cardiovascular Disease: A Genome-wide Association Study.","authors":"Haejung Lee, DaeEun Lee, Sukhyun Jun","doi":"10.1177/10998004251361807","DOIUrl":"https://doi.org/10.1177/10998004251361807","url":null,"abstract":"<p><p><b>Objective:</b> To identify single nucleotide polymorphisms (SNPs) associated with cardiovascular disease (CVD) and examine the association of genetic and lifestyle factors using data from the Korean Genome and Epidemiology Study (KoGES). <b>Methods:</b> A secondary analysis was conducted using Phase 1 data from the Health Examinee (HEXA) cohort, including 26,546 participants (1,919 with CVD and 24,627 controls). Sex-stratified analyses were performed on 17,390 females and 9,156 males. SNPs associated with CVD were identified using PLINK 1.9, and logistic regression models were used to assess associations between CVD and genetic, demographic, and lifestyle factors in IBM SPSS Statistics 27.0. <b>Results:</b> Three SNPs (rs8086325, rs34233878, rs218463) were significantly associated with CVD in the overall sample. In males, rs79682491, rs2540719, and rs2576541 showed significant associations, while in females, rs76830381, rs6496602, rs8086325, and rs34233878 were identified. In multivariate analyses, age ≥60 (OR = 15.56), BMI ≥30 (OR = 4.74), male sex, smoking, low protein intake, low income, and selected SNPs were significantly associated with CVD risk. <b>Conclusion:</b> This study underscores the multifactorial nature of CVD risk, highlighting the joint association of genetic, behavioral, and demographic factors. The observed sex-specific genetic associations reinforce the need for personalized prevention strategies. Nurses are well-positioned to lead efforts in implementing sex-sensitive, genomics-informed approaches to reduce CVD risk and promote cardiovascular health.</p>","PeriodicalId":93901,"journal":{"name":"Biological research for nursing","volume":" ","pages":"10998004251361807"},"PeriodicalIF":2.1,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144746525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}