The open sleep journal最新文献_第5页

Aspects of Slow-Wave EEG Activity During Sleep in Twins Discordant for Chronic Fatigue Syndrome 慢性疲劳综合征双胞胎睡眠时慢波脑电图活动的各个方面

The open sleep journal Pub Date : 2009-05-13 DOI: 10.2174/1874620900902010020

R. Hoffmann, J. Goldberg, N. Watson, D. Buchwald, R. Armitage

{"title":"Aspects of Slow-Wave EEG Activity During Sleep in Twins Discordant for Chronic Fatigue Syndrome","authors":"R. Hoffmann, J. Goldberg, N. Watson, D. Buchwald, R. Armitage","doi":"10.2174/1874620900902010020","DOIUrl":"https://doi.org/10.2174/1874620900902010020","url":null,"abstract":"Chronic Fatigue Syndrome (CFS) is a disease characterized by high levels of daytime fatigue. Complaints such as unrefreshing sleep and insomnia are common. Polygraphic studies of sleep in CFS patients have found evidence of dis- turbed sleep, but controls in these studies were often not adequate to evaluate differences specific to CFS. Watson, et al. (1) and Ball, et al. (2) used a co-twin control design to eliminate virtually all sources of confounding variance and found a small difference between levels of Stage 2 sleep (lower in CFS) and Stage 3 sleep (higher in CFS), where CFS ill twins showed a higher level of sleep complaint than the healthy twins which was not reflected in their sleep physiology. The current study will apply more sensitive measures of sleep EEG to these data to examine differences more closely. A co- twin control study was performed on 10 pairs of identical twins discordant for CFS. Data from the second sleep night were analyzed using fast-fourier analysis (FFT) and finally measures of slow-wave activity (SWA). Data for NREM peri- ods was analyzed. There was a significant interaction in SWA for Twin x NREM period for the first 2 NREM periods with the healthy twins having more SWA in the first NREM period and less in the second NREM period. While overall SWA activity did not differentiate the groups, the distribution of SWA in the first 2 NREM periods could be associated with the experience of unrefreshing sleep. Typically, SWA in the first NREM period is associated with deep restorative sleep. Lower SWA in NREMP 1 in the ill CFS twins suggests that this process is compromised resulting in the experience of less refreshing sleep.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"2 1","pages":"20-25"},"PeriodicalIF":0.0,"publicationDate":"2009-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68089341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mexican Version of the Epworth Sleepiness Scale 墨西哥版的爱普沃斯嗜睡量表

The open sleep journal Pub Date : 2009-04-09 DOI: 10.2174/1874620900902010006

U. Jiménez-Correa, R. Haro, A. Poblano, Y. Arana-Lechuga, Guadalupe Terán-Pérez, R. O. González-Robles, J. Velázquez-Moctezuma

{"title":"Mexican Version of the Epworth Sleepiness Scale","authors":"U. Jiménez-Correa, R. Haro, A. Poblano, Y. Arana-Lechuga, Guadalupe Terán-Pérez, R. O. González-Robles, J. Velázquez-Moctezuma","doi":"10.2174/1874620900902010006","DOIUrl":"https://doi.org/10.2174/1874620900902010006","url":null,"abstract":"The Epworth Sleepiness Scale (ESS) has been reputed as a quick, valid, and reliable method to assess Daytime sleepiness (DS). Since its publication, it has been translated into a number of languages. Our aim was to determine valid- ity and reliability indicators of an Spanish language version ESS for Mexican population. Considering that in developing countries the majority of persons use public transportation, validity and reliability indicators were also assessed utilizing the ESS without item 8. ESS was applied to a Group of college students (GCS), a selected group of Healthy subjects (HS), and a Group of patients with Sleep disorders (GPSD). We made an ESS comparison among the 3 groups, calculated the correlation between the ESS and the Multiple Sleep Latency Test (MSLT) and determined construct validity and internal consistency. GCS and GHS had lower ESS scores than GPSD. Regarding convergence validity, we obtained a negative correlation between the ESS and the MSLT; we also found a rise in the ESS score associated with an increase in the Ap- nea-hypopnea index (AHI). With respect to construct validity (employing main component analysis and varimax rotation), we found that one factor explains 52.01% of variance. We determined that the ESS internal consistency was 0.85. When item eight was suppressed, validity and reliability remained acceptable. The present ESS Spanish-language exhibited suit- able levels of validity and reliability. Use of the ESS, suppressing item eight, allows assessment of DS more accurately in individuals who do not travel by automobile on a regular basis.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"2 1","pages":"6-10"},"PeriodicalIF":0.0,"publicationDate":"2009-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68089330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 19

Impact, Perception, Role and Expectations of Sleep Partners of Patients Suffering from Sleep Apnea Syndrome and Treated at Home by CPAP: Results of a Large Scale Study of More than 900 Patients 睡眠呼吸暂停综合征患者在家接受CPAP治疗对睡眠伴侣的影响、感知、作用和期望:一项针对900多名患者的大规模研究结果

The open sleep journal Pub Date : 2009-04-01 DOI: 10.2174/1874620900902010001

E. Ellenberg, A. Didier, Dehecq Bertrand, Crone Vronique, I. Laurence, Martinez Philippe, C. Monique, R. Jean-Louis

{"title":"Impact, Perception, Role and Expectations of Sleep Partners of Patients Suffering from Sleep Apnea Syndrome and Treated at Home by CPAP: Results of a Large Scale Study of More than 900 Patients","authors":"E. Ellenberg, A. Didier, Dehecq Bertrand, Crone Vronique, I. Laurence, Martinez Philippe, C. Monique, R. Jean-Louis","doi":"10.2174/1874620900902010001","DOIUrl":"https://doi.org/10.2174/1874620900902010001","url":null,"abstract":"Objective: Sleep apnea is a breathing disorder requiring treatment by CPAP. The impact of sleep apnea and how the condition and its treatment are perceived by partners have been studied in small populations. However, few large scale studies have focused on the role and expectations of partners of patients treated with CPAP. Methods: descriptive study of responses to questionnaires sent to 2,059 patients treated for Sleep apnea by CPAP for 6 months and to their partners. Results: 922 questionnaires returned by patients, 673 by partners. 37% sought medical help for the first time upon the partner's initiative. Male patients evoke the breathing pauses occurring at night reported by their partner and a decrease in sexual activity. Female patients focus more on the quality of sleep, tiredness and signs relating to depression. Male pa- tients were more often accompanied by their sleep partner than female patients. For 80% of patients, the partner had a positive effect on initiation of the treatment. Sleep partners talk openly with the patients about the treatment (93%) and encourage them to continue with it (93%). For sleep partners, the benefits of treatment are essentially felt with respect to the quality of sleep. Overall, the benefits of the treatment outweigh the constraints. Conclusions: Sleep apnea and CPAP undoubtedly have an effect on partners. The latter play an important role in the ini- tiation and continuation of the treatment.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"2 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2009-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68089858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Serotonergic System in the Central Nucleus of Amygdala Mediates Cannabidiol- Induced Sleep Alteration 杏仁核中央核的血清素能系统介导大麻二酚诱导的睡眠改变

The open sleep journal Pub Date : 2008-09-03 DOI: 10.2174/1874620900801010058

P. Yi, Y. Hsiao, C. Tsai, T. Jan, Chin-Yu Lu, F. Chang

{"title":"Serotonergic System in the Central Nucleus of Amygdala Mediates Cannabidiol- Induced Sleep Alteration","authors":"P. Yi, Y. Hsiao, C. Tsai, T. Jan, Chin-Yu Lu, F. Chang","doi":"10.2174/1874620900801010058","DOIUrl":"https://doi.org/10.2174/1874620900801010058","url":null,"abstract":"Cannabidiol (CBD) is one of the psycho-inactive constituents of marijuana, the Cannabis sativa. The pharma- cological property of CBD, especially the anxiolytic effect, is significant in the therapeutic purposes. The central nucleus of amygdala (CeA) plays a key role in the anxiety and its related behavioral responses (e.g. sleep-wake activity), and sero- tonin is one of the major mediators. However, the sleep-wake effect of CBD remains unclear. This study was designed to elucidate the effects of CBD on sleep-wake alteration and the involvement of serotonin in the CeA. Administrations of 5- hydroxytryptamine (5-HT), 5-HT1A receptor partial agonist (buspirone), 5-HT2 antagonist (ritanserin), cannabinoid CB1 receptor agonist (ACEA), or CB1 antagonist (AM-251) were employed to elucidate the action of CBD on CeA presynaptic CB1 receptors, serotonergic activity and the subsequent sleep alteration. We found that microinjection of CBD into the CeA prior to the beginning of the light period dose-dependently decreased slow wave sleep (SWS) with limited effect on rapid eye movement sleep (REMS). CBD-induced SWS suppression during the light period could be mimicked by admin- istering serotonin into the CeA. Buspirone and ritanserin dose-dependently blocked CBD-induced SWS decrease. Fur- thermore, administration of AM-251 exhibits similar effect as that of CBD on sleep-wake activity, and the CBD-induced SWS decrease was partially blocked by ACEA. These observations suggest that CBD acting on the CeA neurons de- creases SWS during the light phase, which is at least partially mediated by the consequence of antagonizing presynaptic CB1 receptors, enhancing serotonin release from the presynaptic terminals and subsequently acting on the postsynaptic 5- HT2 receptors.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"1 1","pages":"58-68"},"PeriodicalIF":0.0,"publicationDate":"2008-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68089846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Clinical Significance of Periodic Limb Movement Disorder (PLMD) in Insomnia Patients 失眠患者周期性肢体运动障碍(PLMD)的临床意义

The open sleep journal Pub Date : 2008-08-08 DOI: 10.2174/1874620900801010052

Borge Sivertsen, Siri Omvik, S. Straume, S. Pallesen, B. Bjorvatn, O. Havik, I. Nordhus

{"title":"Clinical Significance of Periodic Limb Movement Disorder (PLMD) in Insomnia Patients","authors":"Borge Sivertsen, Siri Omvik, S. Straume, S. Pallesen, B. Bjorvatn, O. Havik, I. Nordhus","doi":"10.2174/1874620900801010052","DOIUrl":"https://doi.org/10.2174/1874620900801010052","url":null,"abstract":"While periodic limb movement disorder (PLMD) in some studies has been linked with a range of negative con- sequences, others have questioned the validity of the diagnosis. The aim of the present study was to investigate the clinical significance of co-morbid PLMD in terms of daytime impairment in insomnia patients when defined in accordance with the new diagnostic criteria. 64 older adults complaining of insomnia (mean age = 61.9) were included in the study, and as- sessed with polysomnography, a sleep diary, the Epworth Sleepiness Scale, and a computerized vigilance test. In all, 28 patients had a PLM-index above 15 on at least one polysomnography registration; while the remaining 36 participants served as comparison group (comprising insomniacs patients without co-morbid PLMD). Adjusting for the potential con- founding effects of demographics, apnea/hypopneas and symptoms of restless legs syndrome (RLS), we found no signifi- cant associations between PLMD and daytime sleepiness (measured with both subjective and objective measures). These findings illustrate that daytime symptoms of insomnia and PLMD may be difficult to distinguish, thus supporting the no- tion that the clinical significance of PLMD may be questionable.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"1 1","pages":"52-57"},"PeriodicalIF":0.0,"publicationDate":"2008-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68089823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Developing Architectural Lighting Designs to Improve Sleep in Older Adults 开发建筑照明设计以改善老年人的睡眠

The open sleep journal Pub Date : 2008-08-04 DOI: 10.2174/1874620900801010040

M. Figueiro, Elyse Saldo, M. Rea, Karen Kubarek, J. Cunningham, M. Rea

{"title":"Developing Architectural Lighting Designs to Improve Sleep in Older Adults","authors":"M. Figueiro, Elyse Saldo, M. Rea, Karen Kubarek, J. Cunningham, M. Rea","doi":"10.2174/1874620900801010040","DOIUrl":"https://doi.org/10.2174/1874620900801010040","url":null,"abstract":"This paper discusses a proposed 24-hr lighting scheme for older adults that can positively impact the aging vis- ual, circadian and perceptual systems. New lighting was installed in eight private rooms in an assisted living facility. Measurements of residents' sleep quality and circadian rest-activity patterns were obtained, before and after the new light- ing was installed. Consistent with predictions based upon previous research, the subjects who completed the study showed an improvement in sleep quality and rest/activity rhythms under the new 24-hr lighting scheme. In addition, all study par- ticipants reported a strong preference for the 24-hr lighting. The new lighting not only provides older adults with good lighting for performing their routine visual tasks, but also promotes high circadian light stimulation during the day and low circadian light stimulation at night. Although not studied here, but also discussed as part of the 24-hr lighting scheme, is the impact of a previously studied, novel night-light system that provides older adults with enhanced perceptual cues for nighttime navigation within the room. The new 24-hr lighting scheme appears to have important practical implications for improving the quality of life for seniors and will hopefully be adopted by architects, lighting specifiers and engineers.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"99 1","pages":"40-51"},"PeriodicalIF":0.0,"publicationDate":"2008-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68089806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Tolerance of Positive Airway Pressure following Site-Specific Surgery of Upper Airway 特定部位上呼吸道手术后气道正压耐受性

The open sleep journal Pub Date : 2008-06-30 DOI: 10.2174/1874620900801010034

Ho-sheng Lin, R. Toma, Cara Glavin, M. Toma, M. Badr, J. Rowley

{"title":"Tolerance of Positive Airway Pressure following Site-Specific Surgery of Upper Airway","authors":"Ho-sheng Lin, R. Toma, Cara Glavin, M. Toma, M. Badr, J. Rowley","doi":"10.2174/1874620900801010034","DOIUrl":"https://doi.org/10.2174/1874620900801010034","url":null,"abstract":"A significant proportion of patients may require the continued use of positive airway pressure (PAP) following upper airway surgery. The objective of this study is to determine whether site-specific surgical modification of upper air- way improved tolerance to PAP treatment in those patients who continued to use PAP following surgery. Medical records of patients who underwent site-specific surgical modification of upper airway were identified on retrospective chart re- view. Of the 45 patients who had both preoperative and postoperative sleep studies and were successfully contacted, only 16 patients used PAP prior to the surgery and continued to use it following the surgery. Preoperative and postoperative AHI, lowest oxygen saturation, ESS, PAP pressure, PAP tolerability, number of hours per night of PAP use, and BMI were retrieved from medical records as well as phone interviews. Statistical analysis was performed using paired-samples t-tests in these 16 patients. Most of the 16 patients who continued to use PAP following the surgery did not \"respond\" to surgical treatment even though there was a statistically significant drop in AHI (p=0.027). Only 3 patients in this group were considered \"responders\" but they chose to continue the use of PAP because they continue to derive benefit from its use. Majority of these patients underwent UPPP in conjunction with some types of base of tongue procedure(s). Following surgery, statistically significant improvement in PAP tolerance (p=0.003), increased PAP use (p=0.015) and decrease in ti- trated PAP pressure (p=0.013) were noted. We found in this study that tolerance and compliance of PAP improved fol- lowing site-specific upper airway surgery.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"1 1","pages":"34-39"},"PeriodicalIF":0.0,"publicationDate":"2008-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68089761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Older Patients' Experiences of Sleep in the Hospital: Disruptions and Remedies 老年患者在医院的睡眠经历:干扰和补救措施

The open sleep journal Pub Date : 2008-05-15 DOI: 10.2174/1874620900801010029

Chau Yuen Lee, L. Low, S. Twinn

引用次数: 4

Measuring Nightmare Frequency: Retrospective Questionnaires Versus Prospective Logs 测量噩梦频率:回顾性问卷与前瞻性日志

The open sleep journal Pub Date : 2008-04-01 DOI: 10.2174/1874620900801010026

J. Lancee, V. Spoormaker, G. Peterse, J. Bout

引用次数: 3

Sleep Duration and Oxidative Stress: The Buffalo Cardio-Metabolic Occupational Police Stress (BCOPS) Study 睡眠时间和氧化应激:水牛心脏代谢职业警察应激(BCOPS)研究

The open sleep journal Pub Date : 2008-03-25 DOI: 10.2174/1874620900801010015

L. Charles, C. Burchfiel, D. Fekedulegn, J. Violanti, R. Browne, E. McCanlies, M. Andrew

{"title":"Sleep Duration and Oxidative Stress: The Buffalo Cardio-Metabolic Occupational Police Stress (BCOPS) Study","authors":"L. Charles, C. Burchfiel, D. Fekedulegn, J. Violanti, R. Browne, E. McCanlies, M. Andrew","doi":"10.2174/1874620900801010015","DOIUrl":"https://doi.org/10.2174/1874620900801010015","url":null,"abstract":"Our objective was to investigate the cross-sectional association between sleep duration and biomarkers of oxi- dative stress (glutathione (GSH), glutathione peroxidase (GSH-Px), vitamin C, thiobarbituric acid reactive substances (TBARS), and trolox equivalent antioxidant capacity (TEAC)) among police officers. Standardized techniques were used to analyze biomarkers in fasting blood specimens. Mean levels of biomarkers were compared across levels of sleep dura- tion (0-4.9, 5.0-6.9, � 7.0 hours) using ANOVA. Officers' (women=44; men=69) mean age was 39.6 years. Positive trends were observed across sleep categories with mean levels of GSH and vitamin C only among women (p trend=0.156 and 0.022 respectively), with attenuation after risk-factor adjustment. Positive trends were observed for vitamin C among older officers (p trend=0.018) but not younger. No associations were observed between sleep duration and biomarkers among men. Longer sleep duration is associated with higher levels of vitamin C among policewomen and older officers. Additional studies are warranted.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"1 1","pages":"15-25"},"PeriodicalIF":0.0,"publicationDate":"2008-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68089716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0