特定部位上呼吸道手术后气道正压耐受性

Ho-sheng Lin, R. Toma, Cara Glavin, M. Toma, M. Badr, J. Rowley
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引用次数: 2

摘要

很大比例的患者可能需要在上呼吸道手术后继续使用气道正压通气(PAP)。本研究的目的是确定在手术后继续使用PAP的患者中,对上呼吸道进行部位特异性手术修饰是否能提高对PAP治疗的耐受性。在回顾性的图表回顾中确定了接受特定部位上呼吸道手术修饰的患者的医疗记录。在进行术前和术后睡眠研究并成功联系的45例患者中,只有16例患者在手术前使用PAP并在术后继续使用。术前和术后AHI、最低血氧饱和度、ESS、PAP压、PAP耐受性、每晚使用PAP的小时数和BMI从医疗记录和电话访谈中检索。对16例患者采用配对样本t检验进行统计学分析。在16例术后继续使用PAP的患者中,尽管AHI有统计学意义上的显著下降(p=0.027),但大多数患者对手术治疗没有“反应”。该组中只有3名患者被认为是“应答者”,但他们选择继续使用PAP,因为他们继续从PAP的使用中获益。这些患者中的大多数接受了UPPP和某些类型的舌根手术。手术后,PAP耐受性有统计学意义的改善(p=0.003), PAP使用增加(p=0.015), PAP压力降低(p=0.013)。我们在这项研究中发现PAP的耐受性和依从性改善了特定部位上呼吸道手术后的情况。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Tolerance of Positive Airway Pressure following Site-Specific Surgery of Upper Airway
A significant proportion of patients may require the continued use of positive airway pressure (PAP) following upper airway surgery. The objective of this study is to determine whether site-specific surgical modification of upper air- way improved tolerance to PAP treatment in those patients who continued to use PAP following surgery. Medical records of patients who underwent site-specific surgical modification of upper airway were identified on retrospective chart re- view. Of the 45 patients who had both preoperative and postoperative sleep studies and were successfully contacted, only 16 patients used PAP prior to the surgery and continued to use it following the surgery. Preoperative and postoperative AHI, lowest oxygen saturation, ESS, PAP pressure, PAP tolerability, number of hours per night of PAP use, and BMI were retrieved from medical records as well as phone interviews. Statistical analysis was performed using paired-samples t-tests in these 16 patients. Most of the 16 patients who continued to use PAP following the surgery did not "respond" to surgical treatment even though there was a statistically significant drop in AHI (p=0.027). Only 3 patients in this group were considered "responders" but they chose to continue the use of PAP because they continue to derive benefit from its use. Majority of these patients underwent UPPP in conjunction with some types of base of tongue procedure(s). Following surgery, statistically significant improvement in PAP tolerance (p=0.003), increased PAP use (p=0.015) and decrease in ti- trated PAP pressure (p=0.013) were noted. We found in this study that tolerance and compliance of PAP improved fol- lowing site-specific upper airway surgery.
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