The open sleep journal最新文献

{"title":"Estrogens Administration in Female Transsexuals Augmented Delta andRem Sleep Stages after Six Months of Treatment","authors":"Evalinda Barrón-Velázquez, Daniel Santana, P. Espinosa, R. Salín-Pascual","doi":"10.2174/1874620901508010001","DOIUrl":"https://doi.org/10.2174/1874620901508010001","url":null,"abstract":"The transsexual condition (TS) (Gender Dysphoria DSM-5) people have a marked incongruence between the gender they have been assigned at birth and their experienced/expressed gender. There are variations in brain structures that express reproductive behavior mainly in the hypothalamus. Also, there are sleep differences between non-transsexual female and male. This gender dimorphism in the sleep regulation is due to anatomical changes previously reported in the hypothalamus, which would suggest that it could also find significant differences in sleep architecture in transsexual persons, before and after hormonal treatment with estrogens. Six persons diagnosed with gender identity disorder according to DSM IV-TR, were studied. Also 16 healthy volunteers men (n=6) and women (n=10) were included. A polysomnography base study in which a baseline night recording as well as at 3 and 6 months was performed, with a portable polysomnographic system, for MTF transsexuals. Healthy volunteers were studied only one baseline night. Hormone therapy was administered as conjugated estrogens 0.625 mg/d. (PremarinPfizer), within six months of the present protocol, there were measurements of hormone levels at baseline, three to six months. A descriptive analysis of sexual hormones in plasma, before hormone treatment and sleep variables were performed. They were within normal distribution. The Kolmogorov Smirnov test to asses normality within sleep variables showed normal distribution, so that parametric tests for comparison of those variables could be made. The main significant differences between male and female controls were that the second group had short sleep latency and higher REM sleep time and REM sleep percentage. Sleep variables between female controls and MTF after six months of estrogens had differences in sleep stages 2, 3 and REM. Then a correlation analysis between the hormone levels at different time of their administration and percentages for each of the sleep variables at baseline, 3 and 6 months were performed and it was found that the proportion of N2 is linked to changes in the levels of luteinizing hormone having a Person correlation coefficient of 0.484. Finally, an ANOVA and post hoc analysis was performed to see the difference between sleep variables in transsexual subjects at baseline and at 6 months vs. non-transsexual women and men. Conclusions: The main findings of the present study were that after six months of treatment with estrogens in MTF transsexuals there was an increase in sleep stages 2, 3 and REM, comparing with female controls, and that correlates with luteinizing hormone.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"8 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2015-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68092021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mandibular Movements Identify Respiratory Efforts Due to Obstructive Sleep Apnoea in a Pre-school Child","authors":"J. Martinot, Stéphane Denison, F. Senny, Thibert A. Robillard, U. Khatwa, H. Guénard","doi":"10.2174/1874620901407010001","DOIUrl":"https://doi.org/10.2174/1874620901407010001","url":null,"abstract":"Adenotonsillar hypertrophy is a major cause of obstructive sleep apnea (OSAS) in childhood. Increased respiratory effort associated with OSAS is accompanied by an increase in pulse transit time (PTT) but also mandibular movements (MMs) amplify with increased upper airway resistance. We compared dynamic changes in PTT and MMs using a magnetic distance sensor during polysomnography (PSG) in a pre-school child with severe OSAS before and after adenotonsillectomy. The results show that repetitive respiratory effort to overcome upper airway obstruction can be identified in children using MMs.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"4 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2014-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68092003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short Sleeping Time and Job Stress in Japanese White-Collar Workers","authors":"Naoko Nishitani, H. Sakakibara, Izumi Akiyama","doi":"10.2174/1874620901306010104","DOIUrl":"https://doi.org/10.2174/1874620901306010104","url":null,"abstract":"The aim of this study was to clarify the association between sleeping time and job stress in male Japanese workers. Male workers at one manufacturing plant were surveyed about job stress and sleeping time using a self- completed questionnaire. A total of 274 white-collar daytime workers were analyzed. Job stress factors and stress response were assessed using the Job Stress Questionnaire. Sleeping time on working days was divided into ≤ 5 h, 6 h, 7 h, and ≥ 8 h, and associations between job stress factors and stress response were analyzed. Shorter sleeping time was related to overtime work; about a quarter of those with sleep of ≤ 5 h worked more than 15 h overtime per week. Workers with shorter sleeping time, particularly those with ≤ 5 h sleeping time, were more likely to have job stress factors of quantitative workload and interpersonal conflict as well as psychological stress responses, such as anger, fatigue, tension/anxiety, and depressive symptoms. With shorter sleep, in subjects ≤ 39 years, scores of activity and fatigue decreased or increased respectively, whereas in those ≥ 40 years, scores for tension/anxiety and depressive symptoms increased. Shorter sleeping time was related to overtime work and increased job stress in male white-collar workers. Depression symptoms may be more closely associated with shorter sleeping times in workers aged ≥ 40. Adequate sleep duration is important for maintaining mental health.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"6 1","pages":"104-108"},"PeriodicalIF":0.0,"publicationDate":"2013-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68091960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infant Sleep Location: Bed Sharing, Room Sharing and Solitary Sleepingat 6 and 12 Weeks Postpartum","authors":"R. Stremler, E. Hodnett, L. Kenton, Kathryn A. Lee, J. Macfarlane, S. Weiss, J. Weston, A. Willan","doi":"10.2174/1874620901306010077","DOIUrl":"https://doi.org/10.2174/1874620901306010077","url":null,"abstract":"Objectives: Parents may have their infant sleep with them in the same bed (bed sharing [BS]), in the same room, but a separate bed (room sharing [RS]), or a separate room in a separate bed (solitary sleeping [SS]); prevalence estimates of these choices are limited. Little is known regarding the effects of infant sleep location (ISL) on infant or maternal sleep or other health outcomes. Methods: Healthy first-time mothers (n=246) in an RCT of a sleep intervention provided information regarding planned and actual ISL at 6 and 12 weeks postpartum when maternal and infant sleep were measured using actigraphy. Other outcomes included subjective maternal sleep disturbance, breastfeeding exclusivity, fatigue, and depressive symptomatology. Results: Most women (65%) planned RS with their infant; the next most common plan was to use both BS and RS (22%). The most common usual ISL was RS, with 46% of infants RS at 6 weeks and 39% at 12 weeks. Usual BS was common; at 6 weeks 17% of families were usually BS and 12% at 12 weeks. BS to any extent was quite common at 6 (51%) and 12 weeks (41%) postpartum. At 6 weeks, usually BS mothers had shorter stretches of sleep than those usually SS (130 mins vs 156 mins ; p=0.03) and more awakenings than those usually RS and SS (11.2 vs 8.9 vs 8.3; p=0.001). At 12 weeks, mothers who were usually RS had shorter stretches of sleep than those usually SS (164 mins vs 192 mins; p=0.04). There were no significant differences between ISL groups on any other outcomes. Conclusion: There is variation in ISL choice, and ISL changes across the first three months postpartum. Given our findings that ISL has effects on objective maternal sleep outcomes, further prospective, longitudinal research on the effects of ISL on a broad range of health outcomes for infant, mother and partner across the first postpartum year is needed.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"6 1","pages":"77-86"},"PeriodicalIF":0.0,"publicationDate":"2013-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68090695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Sleep In Pregnancy and the Postpartum Period","authors":"L. O’Brien","doi":"10.2174/1874620901306010012","DOIUrl":"https://doi.org/10.2174/1874620901306010012","url":null,"abstract":"Sleep disturbance is common in pregnant women and an increasing number of studies supports a relationship between sleep disturbance and poor pregnancy outcomes. Such outcomes may not only be limited to the health of the mother, such as gestational hypertension and pre-eclampsia, but also to the health of the fetus, such as growth restriction. Despite these findings few obstetric healthcare providers screen their patients for sleep problems. This may be due to the belief that poor sleep in pregnancy is a natural part of the transition to parenthood and is in preparation for the loss of parental sleep that accompanies a newborn, or that the sleep difficulties are mostly transient and get resolved following delivery. Parental sleep difficulties may persist or emerge following delivery and may be associated with mood disorders and family dysfunction. Clearly this has an impact on the wellbeing of the offspring.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"6 1","pages":"12-13"},"PeriodicalIF":0.0,"publicationDate":"2013-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68090959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Qualitative Study of Sleep and Mood in Postpartum Women","authors":"L. Swanson, J. Arnedt, R. Armitage, Jennifer Adams","doi":"10.2174/1874620901306010098","DOIUrl":"https://doi.org/10.2174/1874620901306010098","url":null,"abstract":"Sleep disruption and insomnia are common features of the postpartum period and may predispose women to develop affective illness. The aim of this study was to explore sleep and mood during the postpartum period in women at risk forpostpartum depression. Thirteen postpartum women participated in focus groups designed to elicit information about sources of sleep disruption, how sleep changes impacted their mood, and their preferences for insomnia treatments. Transcripts from the focus groups were analyzed using a grounded theory framework. Major themes included: mental arousal and breastfeeding are major sources of sleep disruption; women are ambivalent about accessing nighttime support; it is difficult for women to prioritize sleep; poor sleep leads to mood dysregulation; and women prefer non- pharmacological treatments for insomnia. Understanding sleep from the perspective of postpartum women can help inform treatments for insomnia in this population.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"6 1","pages":"98-103"},"PeriodicalIF":0.0,"publicationDate":"2013-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68091944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"24-Hour Sleep Duration in Early Gestation is Associated with Increased Markers of Inflammation Among Women with a History of Preeclampsia","authors":"M. Okun, J. Roberts, A. Begley, J. Catov, T. Patrick","doi":"10.2174/1874620901306010014","DOIUrl":"https://doi.org/10.2174/1874620901306010014","url":null,"abstract":"Background: Sleep duration, both short and long, is recognized as a potential contributor to adverse health conditions. This study evaluated whether long sleep duration in early gestation (15 weeks) was associated with increased circulating concentrations of inflammatory cytokines across pregnancy. Methods: Self-reported 24-hour sleep duration and blood samples were obtained concurrently at 15, 24 and 36 weeks gestation in 85 pregnant women with a history of preeclampsia. Plasma samples were assayed for the inflammatory cytokines IL-2, -6, -8, IFNγ, TNFα, GM-CSF and anti-inflammatory cytokines IL-4, -5, and -10 using Luminex technology. A ratio of pro-to-anti-inflammatory cytokines was calculated using multiples of the median (MOMs) for each relevant cytokine type to normalize the data for comparison. Data were analyzed using repeated measures mixed models. Results: Women with long sleep (≥ 9 hours) at 15 weeks gestation had higher IL-6 concentrations throughout gestation than women who were regular sleepers (p = .003). No other cytokine or the ratio of pro-to-inflammatory cytokines differed between groups. No interactions of group by time were significant. Conclusions: The tendency to sleep for more than 9 hours in early pregnancy may contribute to increased low-grade inflammation as evidenced by higher circulating concentrations of IL-6. This may initiate or augment pre-existing pathophysiology associated with adverse pregnancy outcomes. While, our data are preliminary, they direct further investigation to determine whether this association increases risk for adverse pregnancy outcomes.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"15 1","pages":"14-22"},"PeriodicalIF":0.0,"publicationDate":"2013-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68090972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of Sleep Disordered Breathing in Pregnancy","authors":"G. Bourjeily, Jeffrey Mazer, M. Paglia","doi":"10.2174/1874620901306010028","DOIUrl":"https://doi.org/10.2174/1874620901306010028","url":null,"abstract":"Sleep disordered breathing has been linked to adverse cardiovascular outcomes in the general population. In pregnancy, sleep disordered breathing has also been linked to pathologic disorders that have been associated with long term cardiovascular and metabolic outcomes such as gestational hypertensive disorders and gestational diabetes mellitus. Endothelial dysfunction, sympathetic stimulation and inflammation are among the mechanisms proposed to explain the association with adverse outcomes. In addition to mechanistic research, future efforts need to focus on the effect of therapy on such outcomes.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"6 1","pages":"28-36"},"PeriodicalIF":0.0,"publicationDate":"2013-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68090513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep Disordered Breathing in Pregnancy: An Obstetric Anesthesiologist's Perspective","authors":"A. Bullough","doi":"10.2174/1874620901306010044","DOIUrl":"https://doi.org/10.2174/1874620901306010044","url":null,"abstract":"Anesthesiologists play a pivotal role in the management of high risk obstetric patients on labor and delivery. In the past decade sleep disordered breathing (SDB) in pregnancy and its associated comorbidities of difficult airway, pregnancy related hypertensive diseases; preeclampsia, gestational diabetes and intrauterine growth restriction were recognized and investigated. Moderate to severe SDB affects 1-5% of women of childbearing age although it is likely much higher as the majority of women with SDB remain undiagnosed. The American Society of Anesthesiologists has published obstructive sleep apnea (OSA) practice guidelines for the general surgical population but not the obstetric patient and there is no discussion of this condition in the updated ASA practice guidelines for obstetric anesthesia. Also, validated OSA questionnaires used to screen for OSA in the general population are not appropriate tools to use in high risk parturients. This article discusses how to recognize and optimize clinical anesthetic management of the high risk parturient diagnosed with SDB. It also considers some of the unique physiological changes of pregnancy that impact the parturient with SDB and questionably the fetus.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"6 1","pages":"44-53"},"PeriodicalIF":0.0,"publicationDate":"2013-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68090591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal Sleep and Fetal Outcome","authors":"R. Tauman","doi":"10.2174/1874620901306010063","DOIUrl":"https://doi.org/10.2174/1874620901306010063","url":null,"abstract":"Pregnancy is associated with profound changes in sleep. Up to 75% of pregnant women experience some form of sleep disruption during pregnancy. The emerging data from recent years suggests that sleep disturbances may represent a novel contributor to adverse pregnancy outcomes and that sleep disorders during pregnancy may affect both maternal and fetal outcomes. In spite of the increased awareness, information specifically addressing sleep disturbances and fetal outcomes is limited. The current review summarizes the existing published literature on the effect of short sleep duration, poor quality sleep and sleep-disordered breathing (SDB) on the developing fetus.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"6 1","pages":"63-67"},"PeriodicalIF":0.0,"publicationDate":"2013-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68090615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}