The open sleep journal最新文献

{"title":"Current Approaches and Challenges to Development of an Individualized Sleep and Performance Prediction Model","authors":"E. Olofsen, H. Dongen, Christopher Mott, T. Balkin, D. Terman","doi":"10.2174/1874620901003010024","DOIUrl":"https://doi.org/10.2174/1874620901003010024","url":null,"abstract":"Workplace safety and productivity will be enhanced considerably with the development and application of in- dividualized sleep and performance prediction models. These are models that predict an individual's operational perform- ance based on his/her unique sleep schedule, individual sleep requirements, and individual pattern of responses to sleep loss across a variety of cognitive performance domains. Progress in the individualization of such models will occur as the result of integrated efforts based on (a) an expanding understanding of the relevant physiological processes underlying the sleep/circadian/performance interactions as well as (b) novel empirical and statistical approaches. In the present paper, an overview is presented of the state of the art of the individualization of sleep and performance models with sections on cur- rent efforts in model integration, the application of Bayesian forecasting techniques to the problem of model individuali- zation, construction of Bayesian confidence intervals for predicted performance, and the problem of generalizability of in- dividualized model predictions - i.e., the problem of using models constructed with performance data from one cognitive domain to predict performance in another cognitive domain. Success in model individualization will ultimately be facili- tated by concerted, coordinated efforts involving multiple scientific entities and stakeholders.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68089800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Increasing Body Mass Index on Obstructive Sleep Apnea in Children~!2010-02-01~!2010-05-06~!2010-06-25~!","authors":"K. Graw-Panzer, H. Muzumdar, S. Jambhekar, N. Goldstein, M. Rao","doi":"10.2174/1874620901003010019","DOIUrl":"https://doi.org/10.2174/1874620901003010019","url":null,"abstract":"","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"3 1","pages":"19-23"},"PeriodicalIF":0.0,"publicationDate":"2010-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68089789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep Macroarchitecture in Depression: Sex Differences~!2009-11-01~!2010-03-01~!2010-04-21~!","authors":"L. Swanson, R. Hoffmann, R. Armitage","doi":"10.2174/1874620901003010012","DOIUrl":"https://doi.org/10.2174/1874620901003010012","url":null,"abstract":"","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"3 1","pages":"12-18"},"PeriodicalIF":0.0,"publicationDate":"2010-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68089774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Subgroup of Patients with Chronic Fatigue Syndrome May Have a Disorder of Arousal","authors":"Toru Nakamura, F. Togo, N. Cherniack, D. Rapoport, B. Natelson","doi":"10.2174/1874620901003010006","DOIUrl":"https://doi.org/10.2174/1874620901003010006","url":null,"abstract":"Objective: Patients with chronic fatigue syndrome complain of unrefreshing sleep, and some have poor sleep indicative of sleep disruption. We hypothesized that some CFS patients had a disorder of arousal which interfered with normal sleep which would manifest itself by difficulty falling asleep after a night of sleep deprivation. To test this, we de- termined sleep latency after a night of sleep deprivation. Methods: Patients and healthy controls, previously habituated to sleeping in a sleep lab, returned for a normal night of sleep and for a night of sleep deprivation followed by determination of latency to fall asleep. Patients also had indwelling catheters to allow repeated sampling of plasma for cortisol, a hormone whose levels might reflect arousal. Results: Five of 15 patients showed delays in falling asleep, relative to the healthy controls. Sleep latency following sleep deprivation correlated inversely with sleep efficiency on the normal sleep night. No significant difference was found in cortisol patterns across time for patients and controls on the sleep deprivation night. However, the slope of the curve was shifted up significantly for patients but not for controls on the normal sleep night. Conclusion: A subgroup of patients has difficulty falling asleep after a night of sleep deprivation. These patients may have a disorder of arousal that interferes with their having normal sleep. CFS patients as a group show a shift upwards in the temporal pattern of cortisol during the night - a possible measure of their being stressed while sleeping.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"190 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68089596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"White Blood Cell Count and Sleep Difficulty Examined by the AthensInsomnia Scale in Shift Workers","authors":"Naoko Nishitani, H. Sakakibara","doi":"10.2174/1874620901003010001","DOIUrl":"https://doi.org/10.2174/1874620901003010001","url":null,"abstract":"The aim of this study was to examine the relation between sleep difficulty and white blood cell (WBC) count in shift workers. This was a cross-sectional study in male Japanese workers at a synthetic fiber plant. The subjects were 212 male workers who underwent an annual workplace health checkup in April 2007. For the WBC count the blood test value from the health checkup was used. With regard to insomnia, subjects were asked the first 5 of the 8 questions on the Athens Insomnia Scale (AIS). An increased WBC count was associated with total AIS score (p<0.05) and work pat- tern (shift work) (p<0.05) in addition to smoking (p<0.001), fasting blood sugar (p<0.01), and BMI (p<0.05). In shift workers, the WBC count was related with total AIS score (p<0.05) and those with higher total AIS score tended to have an increased WBC count (p<0.01). In daytime workers, the count was not associated with AIS score. The present results have shown that shift workers with sleeping problems are more likely to have higher WBC counts, which might suggest low-grade inflammatory changes in those workers. Quality sleep may be necessary for shift workers in particular.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68089553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screening for Obstructive Sleep Apnea: Bayes Weighs in","authors":"M. Bianchi","doi":"10.2174/1874620900902010056","DOIUrl":"https://doi.org/10.2174/1874620900902010056","url":null,"abstract":"A fundamental challenge associated with screening tests is recognition of the impact of disease prevalence upon the predictive value of the result. For example, in the common circumstance of screening for low prevalence dis- eases, even good tests may have unacceptably high false positive rates. The converse situation, screening in high preva- lence populations, is less common but occurs with obstructive sleep apnea (OSA): even ostensibly good screening tests may have unacceptably high false negative rates. The challenge of recognizing false negative OSA screening results has important implications as screens are increasingly implemented in high risk populations. This raises two clinically impor- tant questions: 1) How sensitive and specific should a screening test be to minimize false negative results across a spec- trum of baseline prevalence; and 2) Given a screening test with known sensitivity and specificity, in what range of disease prevalence may the test be reasonably applied? Simple graphics are presented that incorporate acceptable risk thresholds and illustrate combinations of prevalence, sensitivity, and specificity in which disease probability remains high despite a negative test result. Adopting a Bayesian approach, together with acceptable risk thresholds, may help to avoid potential pitfalls of false negative screening results. Although the baseline prevalence in the United States of obstructive sleep apnea (OSA) is estimated in the range of 3- 28% (1), in certain populations the prevalence is much higher. For example, higher prevalence has been reported for patients with refractory epilepsy (33%) (2), recent stroke (58%) (3), refractory hypertension (63%) (4), heart failure (35%) (5), polycystic ovary syndrome (65%) (6), anterior ischemic optic neuropathy (89%) (7), children with Down's Syndrome (63%) (8), and those undergoing bariatric surgery (80%) (9-10). Treatment of OSA may be associated with improved outcomes in some settings (11). One particular area of interest involves OSA in the peri-operative setting, which may be associated with complications and/or longer hospital stay (12-13). Given the limited resources for labora- tory polysomnogram (PSG) as a screening tool, screening questionnaires may assist in OSA risk stratification. A screening tool with the acronym \"STOP-Bang\" was recently developed to provide dichotomous risk stratification (low versus high OSA risk) in general surgical populations (12-13). In this population, adverse outcomes involving res- piratory compromise were increased in the peri-operative period in those with OSA, defined as an apnea-hypopnea index (AHI) >5 by standard PSG. The STOP-Bang screen involves four yes/no patient questions (snoring, daytime tiredness, observed nocturnal apnea, high blood pressure), combined with four yes/no clinical features (BMI >35, age >50, neck circumference >40 cm, male gender). This simple tool was validated in a surgical population (177 patients, including general","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"2 1","pages":"56-59"},"PeriodicalIF":0.0,"publicationDate":"2009-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68089537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Sleep Beyond Our Control","authors":"H. Þorsteinsson, K. Karlsson","doi":"10.2174/1874620900902010048","DOIUrl":"https://doi.org/10.2174/1874620900902010048","url":null,"abstract":"Sleep is mysterious. It is ubiquitous and vital, yet its function remains unknown. There are, however, exceptions from the omnipresence of sleep: Birds that exhibit less sleep drive during migration; cetaceans and dolphins that sidestep the need for sleep by sleeping with one hemisphere at a time; frogs that do not seem to sleep at all; and strains of mice and fruit flies that sleep less than their wild-type counterparts. Moreover, new drugs have been discovered that combat the need for sleep in humans without the well known side effects of common stimulants. In the current review, the different ways of evading sleep will be examined. It will be argued that to understand how sleep can be controlled research efforts need to be extended to non-standard laboratory animals that exhibit different methods of evading sleep. Finally, it is argued that emerging clues point to increased membrane excitability as the common neural process used to execute seemingly different forms of sleep-evasion.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"51 1","pages":"48-55"},"PeriodicalIF":0.0,"publicationDate":"2009-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68089494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Periodic Limb Movements in Complex Sleep Apnea Syndrome","authors":"S. Pusalavidyasagar, T. Kuźniar, E. Olson, T. Morgenthaler","doi":"10.2174/1874620900902010043","DOIUrl":"https://doi.org/10.2174/1874620900902010043","url":null,"abstract":"Introduction: The development of repetitive central apneas during application of CPAP in patients initially showing obstructive apneas, a condition called complex sleep apnea syndrome (CompSAS), implies respiratory control instability. Respiratory control is known to be transiently destabilized by arousals. We hypothesized that PLMS and PLM- related arousals would be more frequent in patients with CompSAS compared to those with obstructive sleep apnea (OSA) and could account for some of the respiratory instability. Methodology: Comparative retrospective review of patients studied in our Sleep Disorders Center. Results: 88 patients with CompSAS were compared with 112 patients with OSA. Total arousal index (TAI), respiratory- related arousal index (RRAI), and PLM-related arousal index (PLMAI) were similar during the diagnostic polysomnogra- phy of CompSAS and OSA patients. Following CPAP application, patients with CompSAS had a higher TAI (27.2 (15.5 - 39.9) vs. 16.6 (10.7 - 26.5); p� 0.001; median (interquartile range)), but a lower PLMI (0 (0 - 21.1) vs. 12.6 (0 - 36.2); p=0.009) and PLMAI (0 (0 - 1.3) vs. 0.8 (0 - 4.2); p=0.004) than patients with OSA. Conclusion: PLMS and PLM-related arousals are not more common in CompSAS than in OSA patients and do not appear to play a significant role in destabilizing respiratory control in CompSAS patients.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"2 1","pages":"43-47"},"PeriodicalIF":0.0,"publicationDate":"2009-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68089483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An overview of sleepiness aspects reflected in balance scale model","authors":"J. Berg","doi":"10.2174/1874620900902010033","DOIUrl":"https://doi.org/10.2174/1874620900902010033","url":null,"abstract":"This overview presents aspects that link sleepiness and are reflected in a model. Sleepiness is a common health problem today, affecting up to one-third of the population and related to many work a ...","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"2 1","pages":"33-42"},"PeriodicalIF":0.0,"publicationDate":"2009-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68089419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of a Bovine Alpha S1-Casein Tryptic Hydrolysate (CTH) on Sleep Disorder in Japanese General Population","authors":"Z. Saint-Hilaire, M. Messaoudi, D. Desor, Toshinori Kobayashi","doi":"10.2174/1874620900902010026","DOIUrl":"https://doi.org/10.2174/1874620900902010026","url":null,"abstract":"This study describes the effect of bovine alpha-S1 casein tryptic hydrolysate (CTH) in a representative sample of day-time workers from the general population of Japan with the occurrence of insomnia during the preceding six months. To investigate this issue, 32 subjects, aged between 25 and 40 years, were examined for the sub- jective sleep quality using the Japanese Pittsburg Sleep Quality Index (PSQI-J). CTH significantly improves the PSQI total score of the treated subjects. It particularly improves the sleep quality after two weeks of treatment, decreases the sleep latency and the daytime dysfunction after four weeks of treatment. Given the antistress properties of CTH, it seems possible to relate the detected improvement of sleep aspects to a reduc- tion of stress following its' chronic administration. In conclusion, being given its beneficial effects and its absence of negative side effects, it would be advantageous to use the CTH to improve chronic insomnia in the Japanese general population. However, further studies will be necessary in order to clarify the essential aspect of CTH properties in the sleep problems.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"2 1","pages":"26-32"},"PeriodicalIF":0.0,"publicationDate":"2009-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68089387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}