{"title":"Objective versus Subjective Cognitive Functioning in Patients with Obstructive Sleep Apnea","authors":"Chang-Wei Chen, Chien-Ming Yang, N. Chen","doi":"10.2174/1874620901205010033","DOIUrl":"https://doi.org/10.2174/1874620901205010033","url":null,"abstract":"Study objectives: Previous studies have found that patients' neurocognitive functions were affected by OSA symptoms. However, no study has focused on the subjective awareness of cognitive impairments. This study used a sub- jective rating scale to evaluate OSA patient perceptions of their cognitive impairments, and explore the relationship be- tween subjective and objective cognitive functions. Methods: An independent-group design was used to compare objective and subjective cognitive performance in both the OSA and control groups. An experimental group of 19 male OSA patients and a control group of 19 normal subjects matched in age and education participated in the study. A neurocognitive test battery that measures attention, memory and executive functions, and the SCIRS (Subjective Cognitive Impairment Rating Scale) that measures subjective perception of cognitive impairments were used. Results: On the neurocognitive test measures, OSA patients demonstrated decreased performance on memory and execu- tive function. On the subjective measures, OSA patients reported a mild to moderately negative impact on attention, memory, and emotional control due to OSA. Conclusions: The results show that OSA patients may not be fully aware of their cognitive impairments, especially with regard to their executive functions. The inconsistency suggests that including neurocognitive tests in the evaluation of sleep-related breathing disorders may provide useful information that cannot be obtained through clinical interviews.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"5 1","pages":"33-42"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68090787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sleep Debt Must be Paid Off: Relationship Between Sleep Loss and Mental Health Among Japanese Workers","authors":"A. Mikami","doi":"10.2174/1874620901205010025","DOIUrl":"https://doi.org/10.2174/1874620901205010025","url":null,"abstract":"Background: Sleep loss and sleep debt are common in Japanese workers. Although cumulative sleep debt may be considered a cause of mental health problems, that relationship has not been empirically confirmed. Sleep loss is de- fined as either self-perceived insufficient sleep and/or insomnia. We calculated sleep debt by subtracting the average number of hours of weekday sleep from hours slept on weekends. Methods: This cross-sectional study was conducted from April 2005 through March 2007 at the Osaka Prefectural Mental Health Center. Participants were 873 workers. First, we investigated characteristics of individuals with awareness of sleep loss. Second, we examined whether reasons for sleep loss (insufficient sleep or insomnia) were associated with sleep hab- its and psychometric variables. Finally, we identified characteristics of subjects with insufficient sleep and examined the association between self-perception of insufficient sleep and mental health. Results: Of the subjects, 64.0% perceived their own sleep loss. Workers with sleep loss related to overwork had signifi- cantly larger sleep debt. Subjects with predictable symptoms of insufficient sleep (short sleep on weekdays, difficulty in awakening or sleep maintenance, large sleep debt, and daytime sleepiness) tended to have higher scores on the General Health Questionnaire-28. Conclusion: Short sleep duration (< 6 hours/weekday), insomnia, and insufficient sleep are different although they can overlap and must be considered separately. Sleep debt might be an essential and useful indicator of insufficient sleep es- pecially caused by overwork. Assessing sleep health, including sleep debt, is important for promoting mental health. We postulate that sleep debt must be paid off.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"5 1","pages":"25-32"},"PeriodicalIF":0.0,"publicationDate":"2012-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68090578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Does Sleep Education Change Sleep Parameters? Comparing Sleep Educa-tion Trials for Middle School Students in Australia and New Zealand","authors":"S. Blunden, G. Kira, M. Hull, R. Maddison","doi":"10.2174/1874620901205010012","DOIUrl":"https://doi.org/10.2174/1874620901205010012","url":null,"abstract":"Background: Adolescents suffer daytime consequences from sleep loss. Sleep education programs have been developed in an attempt to increase sleep knowledge and/or duration. This paper presents data from three trials of the Aus- tralian Centre for Education in Sleep (ACES) program for adolescents. Methods: The ACES program was delivered to 69 Australian adolescents in a pre-post cross-sectional design (mean age 15.2) and 29 New Zealand adolescents in a randomised control trial (mean age 14.8 years). Assessments in sleep parame- ters were undertaken at baseline and post intervention. Results: Where sleep knowledge was evaluated (Australian trials), significant improvements were shown in all trials (All p <0.05). Where sleep duration was assessed (New Zealand trial) significant improvements were found in week and weekend sleep duration (F(1, 27)=4.26, p=0.04). Both, students and teachers found the program feasible, interesting, and educational. Conclusions: ACES sleep education programmes can improve both sleep knowledge and sleep duration in adolescents. Improving the programme so sleep knowledge attained equates to actual sleep behaviour change are areas for future direc- tion. Collectively these findings provide encouraging signs that adolescents can improve their sleep knowledge and behav- iour with sleep education which bodes well for sleep-related health and psycho-social issues.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"5 1","pages":"12-18"},"PeriodicalIF":0.0,"publicationDate":"2012-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68090536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Long-term Complications after Multilevel Surgery for Sleep-related Breathing Disorders","authors":"N. Gebhardt, K. Tschopp","doi":"10.2174/1874620901205010006","DOIUrl":"https://doi.org/10.2174/1874620901205010006","url":null,"abstract":"Multi-site collapse of the upper airway in sleep-related breathing disorders can be treated with multilevel sur- gery. Multilevel surgery is defined as simultaneous interventions at two or more levels of the upper respiratory tract. The aim of the present study is to analyse long-term complications of multi-level surgery with or without hyoid suspension. A group of 192 patients with multilevel surgery with hyoid suspension and 79 patients with multilevel surgery without hyoid suspension were followed prospectively at 3, 12 and 24 months postoperatively. We used a questionnaire asking for foreign body sensation, disorders of swallowing, speech disorders, taste disorders, undesired weight loss and pain. The an- swers were given in a yes/no mode, severity was not graded. Foreign body sensation was the most common complication after multilevel surgery with and without hyoid suspension. Hyoid suspension did not contribute to a higher complication rate. All undesired side effects were reduced with time ex- cept swallowing disorders.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"5 1","pages":"6-11"},"PeriodicalIF":0.0,"publicationDate":"2012-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68090478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Senny, G. Maury, L. Cambron, Amandine Leroux, J. Destiné, R. Poirrier
{"title":"Mandible Behavior in Obstructive Sleep Apnea Patients Under CPAP Treatment","authors":"F. Senny, G. Maury, L. Cambron, Amandine Leroux, J. Destiné, R. Poirrier","doi":"10.2174/1874620901205010001","DOIUrl":"https://doi.org/10.2174/1874620901205010001","url":null,"abstract":"Aim: To investigate whether obstructive sleep apnea (OSA) patients present different behaviors of mandible movements before and under CPAP therapy. Materials and Methodology: In this retrospective study, patients were selected according to inclusion criteria: both the di- agnostic polysomnography recording showing an OSA with an apnea-hypopnea index (AHI) greater than 25 (n/h) and the related CPAP therapy control recordings were available, presence of mandible movement and mask pressure signals in the recordings, and tolerance to the applied positive pressure. Statistical analysis on four parameters, namely the apnea- hypopnea index (AHI), the arousal index (ArI), the average of the mandible lowering during sleep (aLOW), and the aver- age amplitude of the oscillations of the mandible movement signal (aAMPL), was performed on two sets of recordings: OSA and CPAP therapy. Results: Thirty-four patients satisfied the inclusion criteria, thus both OSA and CPAP groups included thirty-four record- ings each. Significant difference (p < 0.001) was found in the OSA group compared with the CPAP group when consider- ing either the four parameters or only the two ones related to mandible movements. Conclusions: When an efficient CPAP pressure is applied, the mouth is less open and presents fewer broad sharp closure movements, and oscillating mandible movements are absent or very small.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"5 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2012-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68090466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hedvik Elisabeth Fosse, S. Pallesen, M. Hysing, K. Stormark
{"title":"Time in bed, sleep sufficiency and emotional and behavioral problems in a general population of 10-12 year old children","authors":"Hedvik Elisabeth Fosse, S. Pallesen, M. Hysing, K. Stormark","doi":"10.2174/1874620901104010029","DOIUrl":"https://doi.org/10.2174/1874620901104010029","url":null,"abstract":"Objective: To examine the relationship between time in bed, sleep sufficiency and emotional and behavioral problems in a general population of children aged 10-12 years (N=5095). Methods: Emotional and behavioral problems were assessed using The Strength and Difficulties questionnaire, which was completed by children, parents and teachers. Data on time in bed, sleep sufficiency and potential confounders (gender, pubertal development, mother's education and family economy) were parent reported. Results: Controlling for gender, pubertal development and socioeconomic status, childrens emotional and behavioral problems as rated by parents were related to insufficient sleep. Self-reported emotional symptoms and parent-reported conduct problems were associated with both shorter time in bed and insufficient sleep. Teacher-reported hyperactivity was associated with long time in bed. Conclusions: Children with self-reported emotional symptoms or parent-reported conduct problems seem to spend too lit- tle time in bed and to obtain insufficient sleep.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"4 1","pages":"29-35"},"PeriodicalIF":0.0,"publicationDate":"2011-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68090453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Kato-Nishimura, I. Mohri, S. Nabatame, M. Akagi, N. Sakai, Y. Miyoshi, K. Ozono, N. Tachibana, M. Taniike
{"title":"nCPAP Improves the Quality of Life of Siblings with Mandibuloacral Dysplasia","authors":"K. Kato-Nishimura, I. Mohri, S. Nabatame, M. Akagi, N. Sakai, Y. Miyoshi, K. Ozono, N. Tachibana, M. Taniike","doi":"10.2174/1874620901104010026","DOIUrl":"https://doi.org/10.2174/1874620901104010026","url":null,"abstract":"Mandibuloacral dysplasia (MAD; MIM 248370, 608612) is a rare progeroid syndrome with autosomal reces- sive inheritance. It is characterized by mandibular hypoplasia, acroosteolysis, delayed closure of the cranial sutures, skin atrophy with mottled hyperpigmentation, stiff joints, and growth retardation. We here report Japanese female siblings with a severe MAD phenotype. Because of extreme micrognathia and small mouth and nostril, obstructive sleep apnea syn- drome (OSAS) was observed in both sisters and was especially life-threatening in the younger sister. Nasal continuous positive airway pressure (nCPAP), which seemed to be only one therapeutic choice for these sisters since impaired bone healing made oral surgical approach including maxillomandibular advancement surgery inapplicable to these sisters, suc- cessfully alleviated OSAS in both sisters. Since the initiation of nCPAP, the younger sister has gained weight constantly and her developmental milestones have been steadily achieved. We conclude that possible life threatening sleep- disordered breathing in the patients with progeroid syndromes should be properly managed.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"4 1","pages":"26-28"},"PeriodicalIF":0.0,"publicationDate":"2011-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68090911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Nocturnal Return of Neglected Regrets: Deficits in Regret Anticipation Predict Insomnia Symptoms","authors":"R. E. Schmidt, M. Linden","doi":"10.2174/1874620901104010020","DOIUrl":"https://doi.org/10.2174/1874620901104010020","url":null,"abstract":"Cognitive accounts of insomnia generally assume that excessive mental activity at bedtime constitutes a central impediment to the process of falling asleep, yet the affective aspects of this mental hyperactivity still remain largely unex- plored. The present study explored whether failures in regret anticipation might lead to a rise of regret-related counterfac- tual thoughts and emotions at bedtime, thereby hindering or interrupting sleep. A sample of 105 undergraduate students completed the newly developed Regret Anticipation Failures Scale (RAFS), the Bedtime Counterfactual Processing Ques- tionnaire (BCPQ), and the Insomnia Severity Index (ISI). Analyses revealed that both regret anticipation failures and bed- time counterfactual processing were related to insomnia severity and that the effect of regret anticipation failures on in- somnia was mediated by the frequency of regret-related thoughts and emotions at bedtime. These findings reveal for the first time that failures in antecedent-focused emotion regulation may contribute to sleeping difficulties.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"4 1","pages":"20-25"},"PeriodicalIF":0.0,"publicationDate":"2011-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68090870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Engstrøm, S. S. Ødegård, T. Sand, L. Stovner, J. Zwart, K. Hagen
{"title":"The Reliability of a New Sleep Screening Questionnaire for Large Population-Based Studies: The Third Nord-Trøndelag Health Study","authors":"M. Engstrøm, S. S. Ødegård, T. Sand, L. Stovner, J. Zwart, K. Hagen","doi":"10.2174/1874620901104010014","DOIUrl":"https://doi.org/10.2174/1874620901104010014","url":null,"abstract":"The aim of the present study was to evaluate the reliability of a new sleep questionnaire (sHUNT-Q) used in the Nord Trondelag Health Study 3 (HUNT 3) performed between 2006 and 2008. Six of nine items were modified from a Norwegian version of the Karolinska Sleep questionnaire (KSQ). Overall, 50,839 (54%) out of 94,194 invited participated in HUNT 3. In a randomly selected group of participants, 297 (53%) out of 563 invited persons attended an interview by neurologists. The reliability of the sleep related questions was evaluated with Cohens kappa by blindly comparing the an- swers in the questionnaire with those from the semi-structured interview. Summary measure scores were calculated by summing the responses of the six modified KSQ questions, the three insomnia-related questions, and the two questions re- lated to respiratory disturbance during sleep. Agreement was calculated for dichotomized sum-score indexes based on 75% and 50% percentile cut-offs. Kappa values for the individual questions ranged from 0.35 to 0.52 in 3 x 3 tables while kappa for summary indexes in 2x2 tables ranged from 0.47 to 0.62. The best agreement between the interview and the questionnaire was found for respiratory disturbance defined as a summary measure score � 50 percentile (kappa value 0.62, 95% CI 0.51-0.74). Reliability did not depend on the time between the HUNT questionnaire and the interview. The KSQ-based summary measure scores from the new sHUNT-Q sleep screening questionnaire may become a useful tool in epidemiological studies for identifying individuals with a persistent sleep disturbance.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"4 1","pages":"14-19"},"PeriodicalIF":0.0,"publicationDate":"2011-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68090859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Conscious Modulation in Normal Sleep","authors":"R. Salín-Pascual","doi":"10.2174/1874620901104010001","DOIUrl":"https://doi.org/10.2174/1874620901104010001","url":null,"abstract":"The phenomenological relationship between consciousness and sleep are reviewed. Consciousness has a self- reflexive component, and while sleeping that is not working as in awakenings. The necessity of some change in narrow concepts of conscious as to be aware and self reflective as well of some aspects of Altered State of Consciousness are ex- plained. In fact, in rapid eye movements (REM) sleep is the sleep stage in which some perception of consciousness is found self-perception in REM sleep is a common phenomenon, but to be aware of that is called lucid dreams. Also sleep paralysis produce some activation of self-awareness. The lack of continuity between cortical areas in delta sleep stages could explain the loss of consciousness is such sleep stage, which support the idea of cortical continuity as a necessary condition for to achieve this integrative process. A ques- tion that emerges after update the knowledge about sleep and consciousness is what is the minimum degree of connec- tivity and activity of the central nervous system for to be conscious? New paradigms in neurosciences like connectome and enactivation, removes reductionist approaches to the main - body issue. Enactive approach could be used as a paradigm to understand cognitive activity in three neurophysiology stages. As a proposal, it can be figured out as follows: (A) In wakefulness, the enactive phenomenon has priority to start whatever action is necessary. A biofeedback to make corrections in order to improve the motor programs, mind theory or any other active strategies; (B) In REM sleep in which there is not external stimuli. Those are generated from the sensorial nuclei in the brainstem which generates internal electrical activity that follows sensorial pathways (i.e., PGO waves) with visual and emotional targets (i.e., occipital visual cortex and amygdale complex) and probably without enactivation, but inner generating stimulation so the brain cortex is activated mainly by brainstem without any anticipatory top-down events; and (C) In delta sleep, in which there are no enactivation and no sensorial inputs, but also there is no interconnectivity in the brain cortex, which is a necessary condition for consciousness and memory. New technical tools as functional magnetic resonance, trans-cranial magnetic stimulation, and magnetic electroencephalo- graphy have open new approaches for develop feasible hypotheses in this field.","PeriodicalId":93625,"journal":{"name":"The open sleep journal","volume":"4 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2011-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68090848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}