PhotoniX最新文献_第3页

Reconfigurable flexible metasurfaces: from fundamentals towards biomedical applications 可重新配置的柔性超表面：从基本原理到生物医学应用

PhotoniX Pub Date : 2024-01-22 DOI: 10.1186/s43074-023-00116-1

Jiangtao Tian, Wenhan Cao

引用次数: 0

Surmounting photon limits and motion artifacts for biological dynamics imaging via dual-perspective self-supervised learning 通过双视角自监督学习克服生物动态成像的光子限制和运动伪影

PhotoniX Pub Date : 2024-01-05 DOI: 10.1186/s43074-023-00117-0

Binglin Shen, Chenggui Luo, Wen Pang, Yajing Jiang, Wenbo Wu, Rui Hu, Junle Qu, Bobo Gu, Liwei Liu

{"title":"Surmounting photon limits and motion artifacts for biological dynamics imaging via dual-perspective self-supervised learning","authors":"Binglin Shen, Chenggui Luo, Wen Pang, Yajing Jiang, Wenbo Wu, Rui Hu, Junle Qu, Bobo Gu, Liwei Liu","doi":"10.1186/s43074-023-00117-0","DOIUrl":"https://doi.org/10.1186/s43074-023-00117-0","url":null,"abstract":"Visualizing rapid biological dynamics like neuronal signaling and microvascular flow is crucial yet challenging due to photon noise and motion artifacts. Here we present a deep learning framework for enhancing the spatiotemporal relations of optical microscopy data. Our approach leverages correlations of mirrored perspectives from conjugated scan paths, training a model to suppress noise and motion blur by restoring degraded spatial features. Quantitative validation on vibrational calcium imaging validates significant gains in spatiotemporal correlation (2.2×), signal-to-noise ratio (9–12 dB), structural similarity (6.6×), and motion tolerance compared to raw data. We further apply the framework to diverse in vivo experiments from mouse cerebral hemodynamics to zebrafish cardiac dynamics. This approach enables the clear visualization of the rapid nutrient flow (30 mm/s) in microcirculation and the systolic and diastolic processes of heartbeat (2.7 cycle/s), as well as cellular and vascular structure in deep cortex. Unlike techniques relying on temporal correlations, learning inherent spatial priors avoids motion-induced artifacts. This self-supervised strategy flexibly enhances live microscopy under photon-limited and motion-prone regimes.","PeriodicalId":93483,"journal":{"name":"PhotoniX","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139102121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Deep tissue super-resolution imaging with adaptive optical two-photon multifocal structured illumination microscopy 利用自适应光学双光子多焦结构照明显微镜进行深层组织超分辨率成像

PhotoniX Pub Date : 2023-12-21 DOI: 10.1186/s43074-023-00115-2

Chenshuang Zhang, Bin Yu, Fangrui Lin, Soham Samanta, Huanhuan Yu, Wei Zhang, Yingying Jing, Chunfeng Shang, Danying Lin, Ke Si, Wei Gong, Junle Qu

{"title":"Deep tissue super-resolution imaging with adaptive optical two-photon multifocal structured illumination microscopy","authors":"Chenshuang Zhang, Bin Yu, Fangrui Lin, Soham Samanta, Huanhuan Yu, Wei Zhang, Yingying Jing, Chunfeng Shang, Danying Lin, Ke Si, Wei Gong, Junle Qu","doi":"10.1186/s43074-023-00115-2","DOIUrl":"https://doi.org/10.1186/s43074-023-00115-2","url":null,"abstract":"Visualization of axons and dendritic spines is crucial in neuroscience research. However, traditional microscopy is limited by diffraction-limited resolution and shallow imaging depth, making it difficult to study neuronal dynamics. Two-photon multifocal structured illumination microscopy (2P-MSIM) provides super-resolution imaging along with a reasonably good penetration, but it is vulnerable to optical aberrations in deep tissues. Herein we present a novel non-inertial scanning 2P-MSIM system incorporated with adaptive optics (AO) which allows for super-resolution imaging with effective aberration correction. Our strategy is designed to correct both laser and fluorescence paths simultaneously using a spatial light modulator and a deformable mirror respectively, providing better results than the individual path corrections. The successful implementation of adaptive optical two-photon multifocal structured illumination microscopy (AO 2P-MSIM) has allowed for the super-resolution imaging of neuronal structures in a mouse brain slice at great depths and dynamic morphological characteristics of zebrafish motoneurons in vivo.","PeriodicalId":93483,"journal":{"name":"PhotoniX","volume":"249 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138826048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chip-to-chip optical multimode communication with universal mode processors 用通用模式处理器的片对片光多模通信

PhotoniX Pub Date : 2023-10-27 DOI: 10.1186/s43074-023-00114-3

Bo Wu, Wenkai Zhang, Hailong Zhou, Jianji Dong, Dongmei Huang, P. K. A. Wai, Xinliang Zhang

{"title":"Chip-to-chip optical multimode communication with universal mode processors","authors":"Bo Wu, Wenkai Zhang, Hailong Zhou, Jianji Dong, Dongmei Huang, P. K. A. Wai, Xinliang Zhang","doi":"10.1186/s43074-023-00114-3","DOIUrl":"https://doi.org/10.1186/s43074-023-00114-3","url":null,"abstract":"Abstract The increasing amount of data exchange requires higher-capacity optical communication links. Mode division multiplexing (MDM) is considered as a promising technology to support the higher data throughput. In an MDM system, the mode generator and sorter are the backbone. However, most of the current schemes lack the programmability and universality, which makes the MDM link susceptible to the mode crosstalk and environmental disturbances. In this paper, we propose an intelligent multimode optical communication link using universal mode processing (generation and sorting) chips. The mode processor consists of a programmable 4 × 4 Mach Zehnder interferometer (MZI) network and can be intelligently configured to generate or sort both quasi linearly polarized (LP) modes and orbital angular momentum (OAM) modes in any desired routing state. We experimentally establish a chip-to-chip MDM communication system. The mode basis can be freely switched between four LP modes and four OAM modes. We also demonstrate the multimode optical communication capability at a data rate of 25 Gbit/s. The proposed scheme shows significant advantages in terms of universality, intelligence, programmability and resistance to mode crosstalk, environmental disturbances, and fabrication errors, demonstrating that the MZI-based reconfigurable mode processor chip has great potential in long-distance chip-to-chip multimode optical communication systems.","PeriodicalId":93483,"journal":{"name":"PhotoniX","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136262424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Ultrafast dissipative soliton generation in anomalous dispersion achieving high peak power beyond the limitation of cubic nonlinearity 超限三次非线性的超高速耗散孤子产生，达到峰值功率

PhotoniX Pub Date : 2023-10-16 DOI: 10.1186/s43074-023-00112-5

Jinhwa Gene, Seung Kwan Kim, Sun Do Lim, Min Yong Jeon

{"title":"Ultrafast dissipative soliton generation in anomalous dispersion achieving high peak power beyond the limitation of cubic nonlinearity","authors":"Jinhwa Gene, Seung Kwan Kim, Sun Do Lim, Min Yong Jeon","doi":"10.1186/s43074-023-00112-5","DOIUrl":"https://doi.org/10.1186/s43074-023-00112-5","url":null,"abstract":"Abstract The maximum peak power of ultrafast mode-locked lasers has been limited by cubic nonlinearity, which collapses the mode-locked pulses and consequently leads to noisy operation or satellite pulses. In this paper, we propose a concept to achieve mode-locked pulses with high peak power beyond the limitation of cubic nonlinearity with the help of dissipative resonance between quintic nonlinear phase shifts and anomalous group velocity dispersion. We first conducted a numerical study to investigate the existence of high peak power ultrafast dissipative solitons in a fiber cavity with anomalous group velocity dispersion (U-DSAD) and found four unique characteristics. We then built long cavity ultrafast thulium-doped fiber lasers and verified that the properties of the generated mode-locked pulses match well with the U-DSAD characteristics found in the numerical study. The best-performing laser generated a peak power of 330 kW and a maximum pulse energy of 80 nJ with a pulse duration of 249 fs at a repetition rate of 428 kHz. Such a high peak power exceeds that of any previous mode-locked pulses generated from a single-mode fiber laser without post-treatment. We anticipate that the means to overcome cubic nonlinearity presented in this paper can give insight in various optical fields dealing with nonlinearity to find solutions beyond the inherent limitations.","PeriodicalId":93483,"journal":{"name":"PhotoniX","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136113709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Full degree-of-freedom polarization hologram by freeform exposure and inkjet printing 采用自由曝光和喷墨印刷的全自由度偏振全息图

PhotoniX Pub Date : 2023-10-13 DOI: 10.1186/s43074-023-00111-6

Jianghao Xiong, Haizheng Zhong, Dewen Cheng, Shin-Tson Wu, Yongtian Wang

{"title":"Full degree-of-freedom polarization hologram by freeform exposure and inkjet printing","authors":"Jianghao Xiong, Haizheng Zhong, Dewen Cheng, Shin-Tson Wu, Yongtian Wang","doi":"10.1186/s43074-023-00111-6","DOIUrl":"https://doi.org/10.1186/s43074-023-00111-6","url":null,"abstract":"Abstract Since the invention of holography by Dennis Gabor, the fabrication of holograms has mainly relied on direct recording of wavefront by engraving the intensity fringes of interfering electric fields into the holographic material. The degree-of-freedom (DoF) is often limited, especially for its usage as a holographic optical element in imaging or display systems, as what is recorded is what to use. In this work, based on the emerging self-assembled photo-aligned liquid crystal, a polarization hologram with full DoF for local manipulation of optical structure is demonstrated. The ability to record an arbitrary wavefront (in-plane DoF) is achieved by freeform surface exposure, while the local adjustment of deposited liquid crystal (out-of-plane DoF) is realized by inkjet printing. The methodology for designing and fabricating such a hologram is exemplified by building a full-color retinal scanning display without color crosstalk. Here, the arbitrary wavefront modulation capability helps to eliminate the aberrations caused by mismatched exposure and display wavelengths. The local liquid crystal adjustment ability enables the suppression of crosstalk by variation of chiral pitch and film thickness to tune the peak and valley of Bragg diffraction band. The demonstrated method is expected to greatly impact the fields of advanced imaging and display, such as augmented reality and virtual reality, that require optics with an ultrathin form factor and high degrees of design freedom simultaneously.","PeriodicalId":93483,"journal":{"name":"PhotoniX","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135858173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Digital staining in optical microscopy using deep learning - a review 使用深度学习的光学显微镜数字染色技术综述

PhotoniX Pub Date : 2023-10-10 DOI: 10.1186/s43074-023-00113-4

Lucas Kreiss, Shaowei Jiang, Xiang Li, Shiqi Xu, Kevin C. Zhou, Kyung Chul Lee, Alexander Mühlberg, Kanghyun Kim, Amey Chaware, Michael Ando, Laura Barisoni, Seung Ah Lee, Guoan Zheng, Kyle J. Lafata, Oliver Friedrich, Roarke Horstmeyer

{"title":"Digital staining in optical microscopy using deep learning - a review","authors":"Lucas Kreiss, Shaowei Jiang, Xiang Li, Shiqi Xu, Kevin C. Zhou, Kyung Chul Lee, Alexander Mühlberg, Kanghyun Kim, Amey Chaware, Michael Ando, Laura Barisoni, Seung Ah Lee, Guoan Zheng, Kyle J. Lafata, Oliver Friedrich, Roarke Horstmeyer","doi":"10.1186/s43074-023-00113-4","DOIUrl":"https://doi.org/10.1186/s43074-023-00113-4","url":null,"abstract":"Abstract Until recently, conventional biochemical staining had the undisputed status as well-established benchmark for most biomedical problems related to clinical diagnostics, fundamental research and biotechnology. Despite this role as gold-standard, staining protocols face several challenges, such as a need for extensive, manual processing of samples, substantial time delays, altered tissue homeostasis, limited choice of contrast agents, 2D imaging instead of 3D tomography and many more. Label-free optical technologies, on the other hand, do not rely on exogenous and artificial markers, by exploiting intrinsic optical contrast mechanisms, where the specificity is typically less obvious to the human observer. Over the past few years, digital staining has emerged as a promising concept to use modern deep learning for the translation from optical contrast to established biochemical contrast of actual stainings. In this review article, we provide an in-depth analysis of the current state-of-the-art in this field, suggest methods of good practice, identify pitfalls and challenges and postulate promising advances towards potential future implementations and applications.","PeriodicalId":93483,"journal":{"name":"PhotoniX","volume":"109 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136295308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transient replica symmetry breaking in Brillouin random fiber lasers 布里渊随机光纤激光器中的瞬态复制对称破缺

PhotoniX Pub Date : 2023-10-09 DOI: 10.1186/s43074-023-00107-2

Liang Zhang, Jilin Zhang, Fufei Pang, Tingyun Wang, Liang Chen, Xiaoyi Bao

{"title":"Transient replica symmetry breaking in Brillouin random fiber lasers","authors":"Liang Zhang, Jilin Zhang, Fufei Pang, Tingyun Wang, Liang Chen, Xiaoyi Bao","doi":"10.1186/s43074-023-00107-2","DOIUrl":"https://doi.org/10.1186/s43074-023-00107-2","url":null,"abstract":"Abstract Replica symmetry breaking (RSB), as a featured phase transition between paramagnetic and spin glass state in magnetic systems, has been predicted and validated among random laser-based complex systems, which involves numerous random modes interplayed via gain competition and exhibits disorder-induced frustration for glass behavior. However, the dynamics of RSB phase transition involving micro-state evolution of a photonic complex system have never been well investigated. Here, we report experimental evidence of transient RSB in a Brillouin random fiber laser (BRFL)-based photonic system through high-resolution unveiling of random laser mode landscape based on heterodyne technique. Thanks to the prolonged lifetime of activated random modes in BRFLs, an elaborated mapping of time-dependent statistics of the Parisi overlap parameter in both time and frequency domains was timely resolved, attributing to a compelling analogy between the transient RSB dynamics and the random mode evolution. These findings highlight that BRFL-based systems with the flexible harness of a customized photonic complex platform allow a superb opportunity for time-resolved transient RSB observation, opening new avenues in exploring fundamentals and application of complex systems and nonlinear phenomena.","PeriodicalId":93483,"journal":{"name":"PhotoniX","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135096003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nonlinear plasmonics: second-harmonic generation and multiphoton photoluminescence 非线性等离子体:二次谐波产生与多光子光致发光

PhotoniX Pub Date : 2023-10-05 DOI: 10.1186/s43074-023-00106-3

Jiyong Wang, Lei Zhang, Min Qiu

引用次数: 0

Correction: Frequency selective fingerprint sensor: the Terahertz unity platform for broadband chiral enantiomers multiplexed signals and narrowband molecular AIT enhancement 校正:频率选择性指纹传感器:宽带手性对映体多路信号和窄带分子AIT增强的太赫兹统一平台

PhotoniX Pub Date : 2023-09-27 DOI: 10.1186/s43074-023-00110-7

Jiaming Lyu, Shengyuan Shen, Lin Chen, Yiming Zhu, Songlin Zhuang

引用次数: 0