PhotoniX最新文献

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Ensemble deep learning-enabled single-shot composite structured illumination microscopy (eDL-cSIM) 集成深度学习单镜头复合结构照明显微镜(eDL-cSIM)
PhotoniX Pub Date : 2025-05-07 DOI: 10.1186/s43074-025-00171-w
Jiaming Qian, Chunyao Wang, Hongjun Wu, Qian Chen, Chao Zuo
{"title":"Ensemble deep learning-enabled single-shot composite structured illumination microscopy (eDL-cSIM)","authors":"Jiaming Qian, Chunyao Wang, Hongjun Wu, Qian Chen, Chao Zuo","doi":"10.1186/s43074-025-00171-w","DOIUrl":"https://doi.org/10.1186/s43074-025-00171-w","url":null,"abstract":"Abstract Structured illumination microscopy (SIM) has emerged as a powerful super-resolution technique for studying protein dynamics in live cells thanks to its wide-field imaging mode and high photon efficiency. However, conventional SIM requires at least nine raw images to achieve super-resolution reconstruction, which limits its imaging speed and increases susceptibility to rapid sample dynamics. Moreover, the reliance of SIM on illumination parameters and algorithmic post-processing renders it vulnerable to reconstruction artifacts, especially at low signal-to-noise ratios. In this work, we propose a single-shot composite structured illumination microscopy method using ensemble deep learning (eDL-cSIM). Without modifying the original SIM setup, eDL-cSIM employs only one composite structured illumination pattern generated by 6-beam interferometry. The resultant composite-coded raw image, which contains multiplexed high-frequency spectral information beyond the diffraction limit, is further processed using ensemble deep learning to predict a high-quality, artifact-free super-resolved image. Experimental results demonstrate that eDL-cSIM integrates the advantages of various state-of-the-art neural networks, enabling robust super-resolution image predictions across different specimen types or structures of interest, and outperforms classical physics-driven methods in terms of imaging speed, reconstruction quality and environmental robustness, while avoiding intricate and specialized algorithmic procedures. These collective advantages make eDL-cSIM a promising tool for fast and robust live-cell super-resolution microscopy with significantly reduced phototoxicity and photobleaching.","PeriodicalId":93483,"journal":{"name":"PhotoniX","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://photonix.springeropen.com/counter/pdf/10.1186/s43074-025-00171-w","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147890477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
Terahertz photons promote neuron growth and synapse formation through cAMP signaling pathway 太赫兹光子通过cAMP信号通路促进神经元生长和突触形成
PhotoniX Pub Date : 2025-04-01 DOI: 10.1186/s43074-025-00165-8
Yuan Zhong, Yun Yu, Yangmei Li, Junkai Yin, Yuankun Sun, Rundong Jiang, Chao Chang
{"title":"Terahertz photons promote neuron growth and synapse formation through cAMP signaling pathway","authors":"Yuan Zhong, Yun Yu, Yangmei Li, Junkai Yin, Yuankun Sun, Rundong Jiang, Chao Chang","doi":"10.1186/s43074-025-00165-8","DOIUrl":"https://doi.org/10.1186/s43074-025-00165-8","url":null,"abstract":"Abstract Neurite outgrowth and synapse formation constitute the cellular basis for the establishment and plasticity of neural networks, crucially involved in cognitive functions. However, the techniques currently available to effectively and specifically modulate these processes remain limited. In this work, we propose a non-drug and non-thermal terahertz (THz) photon modulation approach that enhances neuronal growth and synaptogenesis. Frequency screening experiments show that 34.5 THz photon stimulation could effectively promote neurite elongation and postsynaptic density protein 95 (PSD95) expression by 26.0% in rat hippocampal neurons. Subsequent cellular experiments reveal an upregulation of the cyclic adenosine monophosphate (cAMP) signaling pathway and adenylyl cyclase type 1 (AC1) activity after 34.5 THz photon irradiation. Molecular dynamics simulations suggest that 34.5 THz photons promote the binding between AC1 and ligand, accelerating cAMP generation. In vivo experiments further confirm an increase in hippocampal cAMP levels and dendritic spine density after THz photon stimulation, accompanied by a significant improvement in cognitive performance. Overall, our results suggest THz photon stimulation as an effective and specific method for neuromodulation, promising for future applications in the treatment of cognitive dysfunction.","PeriodicalId":93483,"journal":{"name":"PhotoniX","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s43074-025-00165-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147908695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 18
Sub-nanosecond heat-based logic, writing and reset in an antiferromagnetic magnetoresistive memory. 反铁磁磁阻存储器的亚纳秒热逻辑、写入和复位。
IF 19.1
PhotoniX Pub Date : 2025-01-01 Epub Date: 2025-11-04 DOI: 10.1186/s43074-025-00207-1
M Surýnek, A Farkaš, J Zubáč, P Kubaščík, K Olejník, F Krizek, L Nádvorník, T Ostatnický, R P Campion, V Novák, T Jungwirth, P Němec
{"title":"Sub-nanosecond heat-based logic, writing and reset in an antiferromagnetic magnetoresistive memory.","authors":"M Surýnek, A Farkaš, J Zubáč, P Kubaščík, K Olejník, F Krizek, L Nádvorník, T Ostatnický, R P Campion, V Novák, T Jungwirth, P Němec","doi":"10.1186/s43074-025-00207-1","DOIUrl":"10.1186/s43074-025-00207-1","url":null,"abstract":"<p><p>Thermal logic aims to create thermal counterparts to electronic circuits. In this work, we investigate experimentally the response of an analog memory device based on a thin film of an antiferromagnetic metal CuMnAs to bursts of heat pulses generated by the absorption of femtosecond laser pulses at room ambient temperature. When a threshold temperature in the heat-based short-term memory of the device is exceeded, the output of the in-memory logic operations is transferred within the same device to a long-term memory, where it can be retrieved at macroscopic times. The long-term memory is based on magnetoresistive switching from a reference low-resistive uniform magnetic state to high-resistive metastable nanofragmented magnetic states. The in-memory heat-based logic operations and the conversion of the outputs into the electrically-readable long-term magnetoresistive memory were performed at sub-nanosecond time scales, making them compatible with the GHz frequencies of standard electronics. Finally, we demonstrate the possibility of rapidly resetting the long-term memory to the reference low-resistive state by heat pulses.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1186/s43074-025-00207-1.</p>","PeriodicalId":93483,"journal":{"name":"PhotoniX","volume":"6 1","pages":"46"},"PeriodicalIF":19.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12586222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145460851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real-time wide-field fluorescence lifetime imaging via single-snapshot acquisition for biomedical applications. 实时宽视场荧光寿命成像通过单快照采集生物医学应用。
IF 18
PhotoniX Pub Date : 2025-01-01 Epub Date: 2025-12-19 DOI: 10.1186/s43074-025-00216-0
Vikas Pandey, Euan Millar, Ismail Erbas, Luis Chavez, Jack Radford, Isaiah Crosbourne, Mansa Madhusudan, Gregor G Taylor, Nanxue Yuan, Claudio Bruschini, Stefan T Radev, Margarida M Barroso, Andrew Tobin, Xavier Michalet, Edoardo Charbon, Daniele Faccio, Xavier Intes
{"title":"Real-time wide-field fluorescence lifetime imaging via single-snapshot acquisition for biomedical applications.","authors":"Vikas Pandey, Euan Millar, Ismail Erbas, Luis Chavez, Jack Radford, Isaiah Crosbourne, Mansa Madhusudan, Gregor G Taylor, Nanxue Yuan, Claudio Bruschini, Stefan T Radev, Margarida M Barroso, Andrew Tobin, Xavier Michalet, Edoardo Charbon, Daniele Faccio, Xavier Intes","doi":"10.1186/s43074-025-00216-0","DOIUrl":"10.1186/s43074-025-00216-0","url":null,"abstract":"<p><p>Fluorescence lifetime imaging (FLI) is a powerful tool for investigating molecular processes, microenvironmental parameters, and molecular interactions across tissue to (sub-)cellular levels. Despite its established value in biomedical applications, conventional FLI techniques suffer from long acquisition times, limiting their utility in real-time scenarios like fast biological processes and rapid clinical image-guided interventions. Here, we introduce a novel FLI approach that achieves real-time capability through single-snapshot acquisitions by combining a large-format time-gated SPAD array with dual-gate acquisition capability and a rapid lifetime determination algorithm, thus eliminating time-consuming temporal data collection. We demonstrate this method's scalability and versatility across challenging biomedical applications, such as fast neural dynamics (microscale), multimodal 3D volumetric FLI of tumor organoids (mesoscale), and FLI-guided surgical procedures using tissue-mimicking phantoms (macroscale). Overall, this new methodology significantly enhances FLI's temporal and spatial capabilities, enabling rapid dynamic biomedical signal acquisition and seamless integration into clinical workflows, particularly fluorescence-guided surgery.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1186/s43074-025-00216-0.</p>","PeriodicalId":93483,"journal":{"name":"PhotoniX","volume":"6 1","pages":"58"},"PeriodicalIF":18.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12714819/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145806531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fiber laser based stimulated Raman photothermal microscopy towards a high-performance and user-friendly chemical imaging platform. 基于光纤激光的受激拉曼光热显微镜迈向高性能和用户友好的化学成像平台。
IF 18
PhotoniX Pub Date : 2025-01-01 Epub Date: 2025-09-29 DOI: 10.1186/s43074-025-00196-1
Xiaowei Ge, Yifan Zhu, Dingcheng Sun, Hongli Ni, Yueming Li, Chinmayee V Prabhu Dessai, Ji-Xin Cheng
{"title":"Fiber laser based stimulated Raman photothermal microscopy towards a high-performance and user-friendly chemical imaging platform.","authors":"Xiaowei Ge, Yifan Zhu, Dingcheng Sun, Hongli Ni, Yueming Li, Chinmayee V Prabhu Dessai, Ji-Xin Cheng","doi":"10.1186/s43074-025-00196-1","DOIUrl":"10.1186/s43074-025-00196-1","url":null,"abstract":"<p><p>Stimulated Raman scattering (SRS) microscopy is a highly sensitive chemical imaging technique. However, the SRS imaging performance hinges on two key factors: the reliance on low-noise but bulky solid-state laser sources and stringent sample requirements necessitated by high numerical aperture (NA) optics. Here, we present a fiber laser based stimulated Raman photothermal (SRP) microscope that addresses these limitations. While appreciating the portability and compactness of a noisy source, fiber laser SRP enables a two-order-of-magnitude improvement in signal to noise ratio over fiber laser SRS without balance detection. Furthermore, with the use of low NA, long working distance optics for signal collection, SRP expands the allowed sample space from millimeters to centimeters, which diversifies the sample formats to multi-well plates and thick tissues. The sensitivity and imaging depth are further amplified by using urea for both thermal enhancement and tissue clearance. Together, fiber laser SRP microscopy provides a robust, user-friendly platform for diverse applications.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1186/s43074-025-00196-1.</p>","PeriodicalId":93483,"journal":{"name":"PhotoniX","volume":"6 1","pages":"35"},"PeriodicalIF":18.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12479582/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145208531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deep-learning-enabled temporally super-resolved multiplexed fringe projection profilometry: high-speed kHz 3D imaging with low-speed camera 深度学习支持的时间超分辨多路复用条纹投影轮廓测量法:使用低速相机进行高速 kHz 3D 成像
PhotoniX Pub Date : 2024-08-19 DOI: 10.1186/s43074-024-00139-2
Wenwu Chen, Shijie Feng, Wei Yin, Yixuan Li, Jiaming Qian, Qian Chen, Chao Zuo
{"title":"Deep-learning-enabled temporally super-resolved multiplexed fringe projection profilometry: high-speed kHz 3D imaging with low-speed camera","authors":"Wenwu Chen, Shijie Feng, Wei Yin, Yixuan Li, Jiaming Qian, Qian Chen, Chao Zuo","doi":"10.1186/s43074-024-00139-2","DOIUrl":"https://doi.org/10.1186/s43074-024-00139-2","url":null,"abstract":"<p>Recent advances in imaging sensors and digital light projection technology have facilitated rapid progress in 3D optical sensing, enabling 3D surfaces of complex-shaped objects to be captured with high resolution and accuracy. Nevertheless, due to the inherent synchronous pattern projection and image acquisition mechanism, the temporal resolution of conventional structured light or fringe projection profilometry (FPP) based 3D imaging methods is still limited to the native detector frame rates. In this work, we demonstrate a new 3D imaging method, termed deep-learning-enabled multiplexed FPP (DLMFPP), that allows to achieve high-resolution and high-speed 3D imaging at near-one-order of magnitude-higher 3D frame rate with conventional low-speed cameras. By encoding temporal information in one multiplexed fringe pattern, DLMFPP harnesses deep neural networks embedded with Fourier transform, phase-shifting and ensemble learning to decompose the pattern and analyze separate fringes, furnishing a high signal-to-noise ratio and a ready-to-implement solution over conventional computational imaging techniques. We demonstrate this method by measuring different types of transient scenes, including rotating fan blades and bullet fired from a toy gun, at kHz using cameras of around 100 Hz. Experiential results establish that DLMFPP allows slow-scan cameras with their known advantages in terms of cost and spatial resolution to be used for high-speed 3D imaging tasks.</p>","PeriodicalId":93483,"journal":{"name":"PhotoniX","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142208441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optical steelyard: high-resolution and wide-range refractive index sensing by synergizing Fabry–Perot interferometer with metafibers 光学秤砣:通过法布里-珀罗干涉仪与金属纤维的协同作用实现高分辨率和宽范围折射率传感
PhotoniX Pub Date : 2024-08-15 DOI: 10.1186/s43074-024-00138-3
Lei Zhang, Xinggang Shang, Simin Cao, Qiannan Jia, Jiyong Wang, Wei Yan, Min Qiu
{"title":"Optical steelyard: high-resolution and wide-range refractive index sensing by synergizing Fabry–Perot interferometer with metafibers","authors":"Lei Zhang, Xinggang Shang, Simin Cao, Qiannan Jia, Jiyong Wang, Wei Yan, Min Qiu","doi":"10.1186/s43074-024-00138-3","DOIUrl":"https://doi.org/10.1186/s43074-024-00138-3","url":null,"abstract":"<p>Refractive index (RI) sensors play an important role in various applications including biomedical analysis and food processing industries. However, developing RI sensors with both high resolution and wide linear range remains a great challenge due to the tradeoff between quality (<i>Q</i>) factor and free spectral range (<i>FSR</i>) of resonance mode. Herein, the optical steelyard principle is presented to address this challenge by synergizing resonances from the Fabry–Perot (FP) cavity and metasurface, integrated in a hybrid configuration form on the end facet of optical fibers. Specifically, the FP resonance acting like the scale beam, offers high resolution while the plasmonic resonance acting like the weight, provides a wide linear range. Featuring asymmetric Fano spectrum due to modal coupling between these two resonances, a high <i>Q</i> value (~ 3829 in liquid) and a sensing resolution (figure of merit) of 2664 RIU<sup>−1</sup> are experimentally demonstrated. Meanwhile, a wide RI sensing range (1.330–1.430 in the simulation and 1.3403–1.3757 in the experiment) is realized, corresponding to a spectral shift across several <i>FSR</i>s (four and two <i>FSR</i>s in the simulation and experiment, respectively). The proposed steelyard RI sensing strategy is promising in versatile monitoring applications, e.g., water salinity/turbidity and biomedical reaction process, and could be extended to other types of sensors calling for both high resolution and wide linear range.\u0000</p>","PeriodicalId":93483,"journal":{"name":"PhotoniX","volume":"254 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142208442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultra-low-defect homoepitaxial micro-LEDs with enhanced efficiency and monochromaticity for high-PPI AR/MR displays 用于高 PPI AR/MR 显示屏的超低缺陷同外延微型 LED,具有更高的效率和单色性
PhotoniX Pub Date : 2024-08-14 DOI: 10.1186/s43074-024-00137-4
Yibo Liu, Guobin Wang, Feng Feng, Mengyuan Zhanghu, Zhengnan Yuan, Zichun Li, Ke Xu, Hoi Sing Kwok, Zhaojun Liu
{"title":"Ultra-low-defect homoepitaxial micro-LEDs with enhanced efficiency and monochromaticity for high-PPI AR/MR displays","authors":"Yibo Liu, Guobin Wang, Feng Feng, Mengyuan Zhanghu, Zhengnan Yuan, Zichun Li, Ke Xu, Hoi Sing Kwok, Zhaojun Liu","doi":"10.1186/s43074-024-00137-4","DOIUrl":"https://doi.org/10.1186/s43074-024-00137-4","url":null,"abstract":"<p>The issue of brightness in strong ambient light conditions is one of the critical obstacles restricting the application of augmented reality (AR) and mixed reality (MR). Gallium nitride (GaN)-based micro-LEDs, renowned for their exceptional brightness and stability, are considered the foremost contenders for AR applications. Nevertheless, conventional heteroepitaxial growth micro-LED devices confront formidable challenges, including substantial wavelength shifts and efficiency droop. In this paper, we firstly demonstrated the high-quality homoepitaxial GaN-on-GaN micro-LEDs micro-display, and thoroughly analyzed the possible benefits for free-standing GaN substrate from the material-level characterization to device optoelectronic properties and micro-display application compared with sapphire substrate. The GaN-on-GaN structure exhibits a superior crystal quality with ultra-low threading dislocation densities (TDDs) of ~ 10<sup>5</sup> cm<sup>−2</sup>, which is three orders of magnitude lower than that of GaN-on-Sapphire. Through an in-depth size-dependent optoelectronic analysis of blue/green emission GaN-on-GaN/ Sapphire micro-LEDs from 100 × 100 shrink to 3 × 3 μm<sup>2</sup>, real that a lower forward voltage and series resistance, a consistent emission wavelength (1.21 nm for blue and 4.79 nm for green @ 500 A/cm<sup>2</sup>), coupled with a notable reduction in efficiency droop ratios (15.6% for blue and 28.5% for green @ 500 A/cm<sup>2</sup>) and expanded color gamut (103.57% over Rec. 2020) within GaN-on-GaN 10 μm micro-LEDs. Last but not least, the GaN-on-GaN micro-display with 3000 pixels per inch (PPI) showcased enhanced display uniformity and higher luminance in comparison to its GaN-on-Sapphire counterpart, demonstrating significant potentials for high-brightness AR/MR applications under strong ambient light.</p>","PeriodicalId":93483,"journal":{"name":"PhotoniX","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142208443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real-time monitoring of fast gas dynamics with a single-molecule resolution by frequency-comb-referenced plasmonic phase spectroscopy 利用频率-梳状参比等离子体相位光谱以单分子分辨率实时监测快速气体动力学
PhotoniX Pub Date : 2024-08-13 DOI: 10.1186/s43074-024-00140-9
Duy-Anh Nguyen, Dae Hee Kim, Geon Ho Lee, San Kim, Dong-Chel Shin, Jongkyoon Park, Hak-Jong Choi, Seung-Woo Kim, Seungchul Kim, Young-Jin Kim
{"title":"Real-time monitoring of fast gas dynamics with a single-molecule resolution by frequency-comb-referenced plasmonic phase spectroscopy","authors":"Duy-Anh Nguyen, Dae Hee Kim, Geon Ho Lee, San Kim, Dong-Chel Shin, Jongkyoon Park, Hak-Jong Choi, Seung-Woo Kim, Seungchul Kim, Young-Jin Kim","doi":"10.1186/s43074-024-00140-9","DOIUrl":"https://doi.org/10.1186/s43074-024-00140-9","url":null,"abstract":"<p>Surface plasmon resonance (SPR) sensors are based on photon-excited surface charge density oscillations confined at metal-dielectric interfaces, which makes them highly sensitive to biological or chemical molecular bindings to functional metallic surfaces. Metal nanostructures further concentrate surface plasmons into a smaller area than the diffraction limit, thus strengthening photon-sample interactions. However, plasmonic sensors based on intensity detection provide limited resolution with long acquisition time owing to their high vulnerability to environmental and instrumental noises. Here, we demonstrate fast and precise detection of noble gas dynamics at single molecular resolution via frequency-comb-referenced plasmonic phase spectroscopy. The photon-sample interaction was enhanced by a factor of 3,852 than the physical sample thickness owing to plasmon resonance and thermophoresis-assisted optical confinement effects. By utilizing a sharp plasmonic phase slope and a high heterodyne information carrier, a small atomic-density modulation was clearly resolved at 5 Hz with a resolution of 0.06 Ar atoms per nano-hole (in 10<sup>–11</sup> RIU) in Allan deviation at 0.2 s; a faster motion up to 200 Hz was clearly resolved. This fast and precise sensing technique can enable the in-depth analysis of fast fluid dynamics with the utmost resolution for a better understanding of biomedical, chemical, and physical events and interactions.</p>","PeriodicalId":93483,"journal":{"name":"PhotoniX","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142208444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultrahigh-fidelity full-color holographic display via color-aware optimization 通过色彩感知优化实现超高保真全彩全息显示
PhotoniX Pub Date : 2024-06-01 DOI: 10.1186/s43074-024-00134-7
Chun Chen, Seung-Woo Nam, Dongyeon Kim, Juhyun Lee, Yoonchan Jeong, Byoungho Lee
{"title":"Ultrahigh-fidelity full-color holographic display via color-aware optimization","authors":"Chun Chen, Seung-Woo Nam, Dongyeon Kim, Juhyun Lee, Yoonchan Jeong, Byoungho Lee","doi":"10.1186/s43074-024-00134-7","DOIUrl":"https://doi.org/10.1186/s43074-024-00134-7","url":null,"abstract":"<p>Holographic display offers the capability to generate high-quality images with a wide color gamut since it is laser-driven. However, many existing holographic display techniques fail to fully exploit this potential, primarily due to the system’s imperfections. Such flaws often result in inaccurate color representation, and there is a lack of an efficient way to address this color accuracy issue. In this study, we develop a color-aware hologram optimization approach for color-accurate holographic displays. Our approach integrates both laser and camera into the hologram optimization loop, enabling dynamic optimization of the laser’s output color and the acquisition of physically captured feedback. Moreover, we improve the efficiency of the color-aware optimization process for holographic video displays. We introduce a cascade optimization strategy, which leverages the redundant neighbor hologram information to accelerate the iterative process. We evaluate our method through both simulation and optical experiments, demonstrating the superiority in terms of image quality, color accuracy, and hologram optimization speed compared to previous algorithms. Our approach verifies a promising way to realize a high-fidelity image in the holographic display, which provides a new direction toward the practical holographic display.</p>","PeriodicalId":93483,"journal":{"name":"PhotoniX","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141196669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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