British Poultry Science最新文献_第10页

Development in the progress of overfeeding machinery for foie gras production. 鹅肝生产中过度饲养机械的发展进展。

IF 1.7 3区农林科学

British Poultry Science Pub Date : 2026-06-01 Epub Date: 2026-03-30 DOI: 10.1080/00071668.2025.2599985

R Ning, R Wei, R Wei, C Han

{"title":"Development in the progress of overfeeding machinery for foie gras production.","authors":"R Ning, R Wei, R Wei, C Han","doi":"10.1080/00071668.2025.2599985","DOIUrl":"10.1080/00071668.2025.2599985","url":null,"abstract":"1. Overfeeding is the main method to obtain foie gras (goose or duck fatty liver). The development of overfeeding machines accompanied with the development of foie gras production. From the simplest manual method to the screw driving overfeeding machine, from the pneumatic overfeeding machine to hydraulic overfeeding machine, this equipment is constantly being improved and innovated.2. This is the first comprehensive review on foie gras overfeeding equipment, offering insights for the industry. Overfeeding is the main method for producing foie gras, with overfeeding machinery evolving alongside the industry. This review summarises global and Chinese foie gras production history, machinery development, three main machine types (screw-driving, pneumatic, hydraulic), performance comparisons and trends.3. Hydraulic machines are the optimal choice: integrating advanced technologies, using mixed feeds, featuring flexible tubes to reduce bird injury, ensuring precise feeding (1 g accuracy), high success rates (>95%), superior product quality and efficient operation. They enhance animal welfare by mitigating stress and oesophageal damage. Equipment trends include multi-function integration, flexible feeding tubes and quantitative technologies.","PeriodicalId":9322,"journal":{"name":"British Poultry Science","volume":" ","pages":"432-436"},"PeriodicalIF":1.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147572642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of seasonal variation and transportation distance on welfare and economic parameters in broiler breeder chickens during transit to slaughterhouses. 季节变化和运输距离对运往屠宰场的肉鸡种鸡福利和经济参数的影响。

IF 1.7 3区农林科学

British Poultry Science Pub Date : 2026-06-01 Epub Date: 2025-10-24 DOI: 10.1080/00071668.2025.2559394

E Çavuşoğlu

{"title":"Impact of seasonal variation and transportation distance on welfare and economic parameters in broiler breeder chickens during transit to slaughterhouses.","authors":"E Çavuşoğlu","doi":"10.1080/00071668.2025.2559394","DOIUrl":"10.1080/00071668.2025.2559394","url":null,"abstract":"1. Transporting animals under inappropriate conditions causes pain and suffering to the animals and causes financial loss for the producers. This study investigated the effects of the season and transportation distance on the dead-on-arrival (DOA), reject rate (due to lesions and damage) and body weight loss parameters of the broiler breeder (BB) chickens during transportation from the farm to the slaughterhouse.2. Data was obtained by analysing two-year records of a commercial slaughterhouse in Turkey. During the period examined, 2,452,624 BB were transported and slaughtered to this slaughterhouse by 554 trucks.3. The lowest DOA rate (0.186%) occurred in the summer season and the reject rate in summer (0.104%) was lower than in other seasons. During the monitored period, the effect of season on body weight loss was not statistically significant. When the impact of transportation distance was considered, there was more body weight loss (1.663%) in animals transported over longer distances.4. The data highlighted how important it is to pay attention to transportation conditions of these animals to the slaughterhouse, especially under cold climate conditions and over long distances, both in terms of animal welfare and economics.","PeriodicalId":9322,"journal":{"name":"British Poultry Science","volume":" ","pages":"330-336"},"PeriodicalIF":1.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145353969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effects of multiple low-level mycotoxins contaminated maize on the production performance, antioxidant capacity and immunity of laying hens. 多种低水平真菌毒素污染玉米对蛋鸡生产性能、抗氧化能力和免疫力的影响。

IF 1.7 3区农林科学

British Poultry Science Pub Date : 2026-06-01 Epub Date: 2025-12-10 DOI: 10.1080/00071668.2025.2575982

X Wan, C Zhang, H Ma, Z Yang, H Yang

{"title":"The effects of multiple low-level mycotoxins contaminated maize on the production performance, antioxidant capacity and immunity of laying hens.","authors":"X Wan, C Zhang, H Ma, Z Yang, H Yang","doi":"10.1080/00071668.2025.2575982","DOIUrl":"10.1080/00071668.2025.2575982","url":null,"abstract":" 1. The present study investigated the effects of mild mycotoxin contaminated maize with low levels of aflatoxin B1 (AFB1), zearalenone (ZEA), deoxynivalenol (DON) and fumonisin (FUM) on the production performance, egg quality, antioxidant capacity and immunity of laying hens.2. A total of 378 healthy, 80-week-old Hy-line brown laying hens were divided into three groups (with six replicates per group and 21 hens per replicate): basal control diet (containing 0.534 mg/kg FUM), a diet replacing uncontaminated maize with 50% (containing 24.7 μg/kg AFB1, 37.2 μg/kg ZEA, 0.30 mg/kg DON, and 3.23 mg/kg FUM) or 100% (containing 26.5 μg/kg AFB1, 66.5 μg/kg ZEA, 0.30 mg/kg DON, and 4.73 mg/kg FUM) mycotoxin contaminated maize, respectively, for six weeks experimental period.3. Compared to the control group, hens fed diets with contaminated maize had decreased laying rate, yolk colour and Haugh units, and increased feed-to-egg ratio. The contaminated diets reduced activities of total superoxide dismutase, glutathione peroxidase and glutathione content and increased malondialdehyde content in magnum, isthmus and the oviduct. Serum interleukin-1β (IL-1β) and IL-2 concentrations were enhanced and IL-4 and IL-10 concentrations were reduced by feeding contaminated diets.4. Therefore, feeding contaminated maize impaired the laying performance and egg quality of laying hens, negatively affected the antioxidant and immune system.","PeriodicalId":9322,"journal":{"name":"British Poultry Science","volume":" ","pages":"426-431"},"PeriodicalIF":1.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145713426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative liver transcriptomics of Kadaknath and Aseel chickens reveals molecular basis of their unique nutritional and metabolic traits. Kadaknath鸡和Aseel鸡的肝脏转录组学比较揭示了其独特营养和代谢特征的分子基础。

IF 1.7 3区农林科学

British Poultry Science Pub Date : 2026-06-01 Epub Date: 2025-10-22 DOI: 10.1080/00071668.2025.2562145

M Bagiyal, S Ahlawat, P Chhabra, U Sharma, R Arora, R Sharma, S Khatak, R Parsad, R Gera

{"title":"Comparative liver transcriptomics of Kadaknath and Aseel chickens reveals molecular basis of their unique nutritional and metabolic traits.","authors":"M Bagiyal, S Ahlawat, P Chhabra, U Sharma, R Arora, R Sharma, S Khatak, R Parsad, R Gera","doi":"10.1080/00071668.2025.2562145","DOIUrl":"10.1080/00071668.2025.2562145","url":null,"abstract":"1. Indigenous poultry breeds, like Kadaknath and Aseel, represent invaluable genetic resources, combining unique nutritional and cultural traits. The Kadaknath breed is famed for its black, lean, iron-rich meat with high protein and antioxidant content, while Aseel is a muscular breed prized for endurance, stress tolerance and fighting abilities. Despite their economic and nutritional value, the genetic and metabolic underpinnings of their distinct traits remain underexplored.2. This study conducted a comparative transcriptomic analysis of liver tissue from Kadaknath and Aseel chickens using RNA sequencing (RNA-seq) to uncover the molecular mechanisms driving their phenotypic diversity. The results identified 435 differentially expressed genes (DEG) linked to key processes such as lipid metabolism, oxidative phosphorylation and stress response.3. In Kadaknath chickens, up-regulated genes, including CPT1A, PCK1, TXNRD3 and PPARGC1A, were associated with efficient triglyceride breakdown, strong antioxidant defence and optimised energy metabolism. This likely contributes to the characteristic lean, nutrient-rich meat with high protein and low fat content.4. In contrast, Aseel birds showed elevated expression of stress response genes (MRPL18 and RPL11) and mitochondrial genes (NDUFA1, NDUFA8, NDUFB9 and PTPMT1), supporting its high energy requirements and resilience to stress, crucial for its endurance as a fighter breed. Gene co-expression network analysis highlighted critical hub genes driving these breed-specific adaptations.","PeriodicalId":9322,"journal":{"name":"British Poultry Science","volume":"67 3","pages":"345-354"},"PeriodicalIF":1.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148210265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trends and prevalence of Listeria monocytogenes at poultry abattoirs in Taiwan 2014-2024. 2014-2024年台湾家禽屠宰场单核细胞增生李斯特菌流行趋势及流行趋势。

IF 1.7 3区农林科学

British Poultry Science Pub Date : 2026-06-01 Epub Date: 2025-10-29 DOI: 10.1080/00071668.2025.2564722

H-Y Chou, C-W Tung, Y-C Huang, H-M He, Y-H Hung, I-C Liang, J-H Lin, S-C Li, G-J Lin, M-C Lai

{"title":"Trends and prevalence of Listeria monocytogenes at poultry abattoirs in Taiwan 2014-2024.","authors":"H-Y Chou, C-W Tung, Y-C Huang, H-M He, Y-H Hung, I-C Liang, J-H Lin, S-C Li, G-J Lin, M-C Lai","doi":"10.1080/00071668.2025.2564722","DOIUrl":"10.1080/00071668.2025.2564722","url":null,"abstract":"1. Listeria monocytogenes (L. monocytogenes) is a Gram-positive bacterium and a significant foodborne pathogen that causes listeriosis and occurs in animal products and other foods. Information on the prevalence of L. monocytogenes in poultry carcasses at abattoirs across Taiwan is limited.2. This study investigated L. monocytogenes contamination in poultry carcasses at abattoirs across Taiwan from 2014 to 2024, covering chickens (2014-2024), ducks (2019-2024) and geese (2020-2024) slaughter lines.3. In 2014, 20% of post-chill chickens tested positive for L. monocytogenes (95% CI: 15.1-25.6). Following government intervention and mandatory monitoring across 2014-2024, the prevalence declined steadily and was 0% in 2022-2024. Among all chicken isolates, 73 samples (56.6%) were identified as serogroup 1/2a, 3a; 26 (20.2%) as serogroup 1/2b, 3b; 2 (1.6%) as serogroup 1/2c, 3c; 2 (1.6%) as serogroup 4b, 4d, 4e; and 26 isolates were non-typable. Among all poultry species examined, ducks showed L. monocytogenes in 0.7% (95% CI: 0.0-3.9) of samples in 2019 and 0.5% (95% CI: 0.0-2.7) in 2020; both isolates belonged to serogroup 1/2a, 3a.4. Among all poultry species examined, geese had detection rates of 0.9% (95% CI: 0.0-4.7) in 2020 and 0.8% (95% CI: 0.0-4.6) in 2021. One sample was identified as serogroup 1/2a, 3a, while the other was classified as serogroup 4b, 4d, or 4e.5. Since L. monocytogenes is commonly linked to animal-derived and ready-to-eat foods, nationwide surveillance at abattoirs, together with official controls and industry improvements, is crucial for ensuring food safety.","PeriodicalId":9322,"journal":{"name":"British Poultry Science","volume":" ","pages":"437-444"},"PeriodicalIF":1.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145400063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immunopathological effects of co-exposure to ochratoxin A and FAdV-4 in broilers. 赭曲霉毒素A和FAdV-4共同暴露对肉鸡免疫病理的影响。

IF 1.7 3区农林科学

British Poultry Science Pub Date : 2026-06-01 Epub Date: 2025-12-05 DOI: 10.1080/00071668.2025.2572079

M Imran, M K Saleemi, A Khan, S T Gul, M Jamil, M A Alvi, A Yar

{"title":"Immunopathological effects of co-exposure to ochratoxin A and FAdV-4 in broilers.","authors":"M Imran, M K Saleemi, A Khan, S T Gul, M Jamil, M A Alvi, A Yar","doi":"10.1080/00071668.2025.2572079","DOIUrl":"10.1080/00071668.2025.2572079","url":null,"abstract":"1. Immunosuppressive disorders in poultry pose a significant threat to health and productivity. Ochratoxin A (OTA), a mycotoxin and fowl adenovirus serotype 4 (FAdV-4), the causative agent of hydropericardium syndrome and inclusion body hepatitis, are each known for their immunopathological effects. However, little is known about their combined impact on the immune system of poultry.2. This study investigated the synergistic immunosuppressive and pathological effects of OTA and FAdV-4 co-exposure in broiler chickens. A total of 144, one-day-old broiler chicks were randomly divided into six groups and exposed to OTA (200 ppb or 400 ppb), FAdV-4, or their combinations for 35 d. The FAdV-4 inoculum was PCR-confirmed and administered subcutaneously.3. Birds were monitored for clinical signs, mortality, feed intake and weight gain. Immune function was assessed via SRBC antibody titres, PHA-P - induced lymphoproliferation and carbon clearance assay. Gross and histopathological changes in lymphoid organs were also evaluated.4. The OTA exposure led to dose-dependent immunosuppression, with significant reductions (p ≤ 0.05) in humoral and cell-mediated responses, lymphoid organ atrophy and phagocytic dysfunction. The FAdV-4 infection alone caused immunosuppressive effects, which were significantly exacerbated when combined with OTA. Co-exposed birds exhibited severe lymphocytic depletion, pronounced histological lesions and increased mortality.5. The results demonstrated a synergistic immunosuppressive interaction between OTA and FAdV-4 in broiler chickens. This highlighted the need for routine mycotoxin screening in feed and molecular surveillance of adenoviral infections to prevent compounded immunosuppressive effects and economic losses in commercial poultry production.","PeriodicalId":9322,"journal":{"name":"British Poultry Science","volume":" ","pages":"404-415"},"PeriodicalIF":1.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145676628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Feed particle size and live-attenuated coccidiosis vaccination interact to improve productive performance rather than significant effects on gastrointestinal tract development and meat quality in broilers. 饲料粒度与减毒球虫病疫苗接种相互作用，提高肉鸡生产性能，而对胃肠道发育和肉品质无显著影响。

IF 1.7 3区农林科学

British Poultry Science Pub Date : 2026-06-01 Epub Date: 2025-10-13 DOI: 10.1080/00071668.2025.2567361

M Bozkurt, E Karazeybek

{"title":"Feed particle size and live-attenuated coccidiosis vaccination interact to improve productive performance rather than significant effects on gastrointestinal tract development and meat quality in broilers.","authors":"M Bozkurt, E Karazeybek","doi":"10.1080/00071668.2025.2567361","DOIUrl":"10.1080/00071668.2025.2567361","url":null,"abstract":"1. The present experiment assessed the influence of feed particle size (FPS) and live-attenuated coccidiosis vaccination (COV) at one day of age on the performance, serum biochemistry, gastrointestinal tract (GIT) development and meat quality of broiler chickens.2. The experiment employed a 2 × 2 factorial design of treatments, with two types of FPS (fine and coarse) and two COV programs (with and without vaccine) with six replicate pens per treatment each containing 20 broilers.3. Cereals were passed through 4 mm and 8 mm sieves to create feed mixtures with finely ground (FGF) and coarsely ground (CGF) particle sizes, respectively. Broiler maize, wheat and soybean diets were provided ad libitum from d 1 to 13, 14 to 26 and 27 to 39 of age, respectively.4. At d 13, 26 and 39, birds fed on CGF had higher body weight and weight gain (p < 0.01) compared to those receiving FGF. During the starter period, vaccination increased FI in chicks fed FGF; however, this effect was not observed in birds fed CGF (FPS × COV interaction; p < 0.01). At all control points, significant FPS x COV interactions (p < 0.05) were noted for feed conversion ratio (FCR) with COV negatively impacting FCR only in the FGF-fed broilers.5. Serum biochemistry and GIT characteristics tended to be affected by COV. However, birds fed on CGF had relatively shorter and lighter small intestines compared to those consuming FGF (p < 0.01). The water holding capacity in breast meat decreased in relation to COV (p < 0.01).6. The results indicated that coarse grinding of feed was more effective in accommodating COV-induced growth retardation in broilers when compared to fine grinding.","PeriodicalId":9322,"journal":{"name":"British Poultry Science","volume":" ","pages":"479-492"},"PeriodicalIF":1.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145278940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of male attractiveness on preferential mating, reproductive performance and offspring sex ratio in Chukar breeder partridges (Alectoris chukar). 雄性吸引力对楚卡种鸡择偶、繁殖性能和后代性别比的影响

IF 1.7 3区农林科学

British Poultry Science Pub Date : 2026-06-01 Epub Date: 2025-09-24 DOI: 10.1080/00071668.2025.2559400

M Taghipour, A Akhlaghi, M Naseri, H Daryabari, M Dadpasand, B Nasrollahi, A Farhadi, E D Peebles

{"title":"Effects of male attractiveness on preferential mating, reproductive performance and offspring sex ratio in Chukar breeder partridges (Alectoris chukar).","authors":"M Taghipour, A Akhlaghi, M Naseri, H Daryabari, M Dadpasand, B Nasrollahi, A Farhadi, E D Peebles","doi":"10.1080/00071668.2025.2559400","DOIUrl":"10.1080/00071668.2025.2559400","url":null,"abstract":"1. Female Chukar partridges (Alectoris chukar) strategically adjust maternal reproductive strategies based on male attractiveness, which can influence both reproductive success and offspring sex ratio.2. In this study, female-choice trials identified preferred and non-preferred males. Using a crossover design, each female was sequentially paired with the preferred and non-preferred males, separated by a two-week physiological reset interval.3. Reproductive parameters, including daily egg production, fertility, hatchability (of both set and fertile eggs), embryonic mortality and the primary and secondary offspring sex ratios, were determined via molecular sexing and abdominal cavity examination.4. Notably, offspring sex ratio did not deviate from 50:50 in preferred-male pairings, whereas females that mated with non-preferred males produced a female-biased sex ratio in both the primary and secondary stages.5. In terms of reproductive performance, females paired with preferred males showed significantly higher fertility (~8%) and hatchability (15.27% and 10.63% for set and fertile eggs, respectively), while egg production and embryonic mortality remained unaffected.6. These findings highlighted the importance of allowing female mate choice to improve productivity in commercial systems, especially where male scarcity is a concern.","PeriodicalId":9322,"journal":{"name":"British Poultry Science","volume":" ","pages":"337-344"},"PeriodicalIF":1.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145130000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Gordon Memorial Lecture: A paradigm shift in high pathogenicity avian influenza and perspectives for the future. 戈登纪念讲座：高致病性禽流感的范式转变和对未来的展望。

IF 1.7 3区农林科学

British Poultry Science Pub Date : 2026-06-01 Epub Date: 2026-05-18 DOI: 10.1080/00071668.2026.2653036

I H Brown

{"title":"The Gordon Memorial Lecture: A paradigm shift in high pathogenicity avian influenza and perspectives for the future.","authors":"I H Brown","doi":"10.1080/00071668.2026.2653036","DOIUrl":"10.1080/00071668.2026.2653036","url":null,"abstract":"1. Since 2020, H5 high pathogenicity avian influenza (HPAI) viruses of clade 2.3.4.4b have spread rapidly to all continents except Oceania. This panzootic presents an unprecedented threat to global poultry health, with severe uncertainties as to when it will peak or resolve. The complex epidemiology across multiple ecosystems creates unparallelled challenges following the spread of virus to and within multiple orders of wild birds.2. Sustained infection in numerous species of wild mammals, together with a substantial outbreak in US dairy cattle, increases the animal health threat and elevates risk for increased zoonotic infections. In developed commercial production systems, biosecurity can still be deficient and, if not addressed, can exacerbate the problem further.3. The virus is currently phenotypically stable but continually evolving at the genetic level and these changes need continual tracking to understand future risk and adaptive interventions. This disease not only threatens poultry production and food security worldwide but has a significant impact on biodiversity and improved tracking and knowledge of ecology in wild populations is required.4. Vaccination is a single tool that has potential utility as part of a holistic control plan. In some countries, vaccination has been used successfully to control the disease, but global success remains limited. Improved use of best practice, tailored to practical use in multiple production systems is required for future prevention and control.","PeriodicalId":9322,"journal":{"name":"British Poultry Science","volume":" ","pages":"311-329"},"PeriodicalIF":1.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147962336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Histopathological effects of azithromycin on broilers: immune system alterations and apoptotic changes. 阿奇霉素对肉鸡的组织病理学影响：免疫系统的改变和细胞凋亡的改变。

IF 1.7 3区农林科学

British Poultry Science Pub Date : 2026-06-01 Epub Date: 2025-09-17 DOI: 10.1080/00071668.2025.2559391

A Fotouh, N K Elbarbary, M A Moussa, M S Diab, S M Elshafae

{"title":"Histopathological effects of azithromycin on broilers: immune system alterations and apoptotic changes.","authors":"A Fotouh, N K Elbarbary, M A Moussa, M S Diab, S M Elshafae","doi":"10.1080/00071668.2025.2559391","DOIUrl":"10.1080/00071668.2025.2559391","url":null,"abstract":"1. The following reports an in-vivo study to investigate the toxicity profile of the azithromycin drug in broilers.2. Ninety, 1-d-old Hubbard chicks were purchased from Dakahliah Poultry Company, Egypt and, on d 25 of age, were subdivided into three groups. Group 1 (G1, control) received only drinking water, Group 2 (G2, treatment 1) received 50 mg azithromycin/kg body weight (BW) and Group 3 (G3, treatment 2) received 300 mg azithromycin/kg BW. All treatments were administered orally. Immunological, histopathological, and immunohistochemical assays were performed to evaluate the effect of azithromycin on broiler health.3. The weights of bursa of Fabricius and spleen in azithromycin-treated broilers decreased, particularly in G3. A decrease in both the phagocytic activity and index was evident in the treated groups (G2 and G3). Prominent degenerative changes and necrosis of immune organs were observed in treated chicks. Furthermore, strong immunoreactivity to caspase-3 was observed in the G3 group, which indicated elevated apoptosis in immune organs following exposure to a high-dose of azithromycin.4. It was concluded that administering azithromycin in broilers at a dose of 300 mg/kg impaired the immune function, promoted apoptosis and induced many microscopical alterations in different organs.","PeriodicalId":9322,"journal":{"name":"British Poultry Science","volume":" ","pages":"374-380"},"PeriodicalIF":1.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145074407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0