British Journal of Nutrition最新文献

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Optimising Nutritional Psychiatry Treatment: Investigating the Mediterranean Diet to Improve Symptoms of Major Depressive Disorder (OPTIMISM): a double-blind sham-controlled randomised feeding trial protocol. 优化营养精神病学治疗:调查地中海饮食改善重度抑郁症症状(乐观):一项双盲假对照随机喂养试验方案。
IF 3.1 3区 医学
British Journal of Nutrition Pub Date : 2026-09-14 Epub Date: 2026-05-04 DOI: 10.1017/S0007114526107272
Delyse S Y Tien, Meghan Hockey, Katherine Muller, Taryn Milton, Leena Putkonen, Mohammadreza Mohebbi, Chu K Yao, Felice N Jacka, Daniel Kratochvil, Peter M Haddad, Gerard Clarke, Tetyana Rocks, Heidi M Staudacher
{"title":"Optimising Nutritional Psychiatry Treatment: Investigating the Mediterranean Diet to Improve Symptoms of Major Depressive Disorder (OPTIMISM): a double-blind sham-controlled randomised feeding trial protocol.","authors":"Delyse S Y Tien, Meghan Hockey, Katherine Muller, Taryn Milton, Leena Putkonen, Mohammadreza Mohebbi, Chu K Yao, Felice N Jacka, Daniel Kratochvil, Peter M Haddad, Gerard Clarke, Tetyana Rocks, Heidi M Staudacher","doi":"10.1017/S0007114526107272","DOIUrl":"10.1017/S0007114526107272","url":null,"abstract":"<p><p>Depression is a common mental disorder and a leading cause of global disease burden. Emerging evidence supports diet as an adjunct treatment for depression. Previous studies are limited, meaning it is unclear whether improvements are directly due to dietary change. The Optimising Nutritional Psychiatry Treatment: Investigating the Mediterranean Diet to Improve Symptoms of Major Depressive Disorder (OPTIMISM) trial aims to address this gap through a sham-controlled randomised feeding trial design. The OPTIMISM trial is a 4-week double-blind, sham-controlled, randomised feeding trial. A total of forty-four participants with major depressive disorder in a current major depressive episode of moderate to severe severity will be recruited and randomised to a Mediterranean or a sham control diet, designed to reflect typical dietary intake of the general population. All food will be provided for 4 weeks. Participants will complete assessments and have blood and stool collected at baseline and 4 weeks. The primary outcome is the differential change in clinician-rated depressive severity at 4 weeks. Exploratory outcomes include patient-rated depressive and anxiety symptoms and quality of life. Potential mechanisms will be evaluated through analysis of biological samples. An additional group of twenty-two healthy individuals without depression will also be recruited and will receive a Mediterranean diet for 4 weeks; their data will determine whether clinical and biological responses to the intervention are unique to depression and whether the diet treatment modulates depression-related pathology. If the intervention diet leads to a greater reduction in depressive symptoms compared with a sham control diet, this trial will provide preliminary evidence supporting the use of a Mediterranean diet in the treatment of depression.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"564-571"},"PeriodicalIF":3.1,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between the Mediterranean dietary pattern and metabolic dysfunction-associated steatotic liver disease: a longitudinal analysis from UK BIOBANK. 地中海饮食模式与代谢功能障碍相关脂肪变性肝病(MASLD)之间的关系:来自UK BIOBANK的纵向分析
IF 3.1 3区 医学
British Journal of Nutrition Pub Date : 2026-09-14 Epub Date: 2026-04-29 DOI: 10.1017/S0007114526107351
Elena S George, Ayesha Sualeheen, Christine Freer, Ekavi N Georgeousopoulou, Stuart K Roberts, Robin M Daly, Sze-Yen Tan
{"title":"Association between the Mediterranean dietary pattern and metabolic dysfunction-associated steatotic liver disease: a longitudinal analysis from UK BIOBANK.","authors":"Elena S George, Ayesha Sualeheen, Christine Freer, Ekavi N Georgeousopoulou, Stuart K Roberts, Robin M Daly, Sze-Yen Tan","doi":"10.1017/S0007114526107351","DOIUrl":"10.1017/S0007114526107351","url":null,"abstract":"<p><p>Mediterranean diet (MedDiet) is central to metabolic dysfunction-associated steatotic liver disease (MASLD) management; however, evidence in non-Mediterranean populations is limited. This study examined the association between MedDiet adherence and MASLD, hospitalisation and mortality in a non-Mediterranean population. This longitudinal study included 119 536 UK Biobank adults with at least one 24-hour dietary recall and available sociodemographic and clinical data. Diet quality was assessed using the Modified-Mediterranean Diet Score (M-MedDietScore). MASLD was determined by fatty liver index (FLI) at baseline and by liver imaging in a subgroup. Hospitalisation and mortality data were obtained from linked records, with MASLD outcomes identified using International Classification of Diseases, 10th Revision codes. Binary logistic regression and Cox proportional hazard models estimated Odds Ratio (OR) for MASLD and hazard ratio (HR) for hospitalisation and mortality. Each five-unit increase in M-MedDietScore was associated with 19 % lower OR of MASLD as identified by FLI and confirmed in the imaging sub-analysis in a multivariate adjusted Model 2. Higher adherence to the MedDiet was associated with lower HR of hospitalisation due to liver-related, CVD, diabetes, respiratory and renal disease (all <i>P</i> < 0·05). During a median follow-up of 9·7 years, 5552 deaths occurred. Higher MedDiet adherence was associated with lower HR of all-cause, CVD and extrahepatic cancer mortality and lower all-cause mortality risk in those with MASLD (HR: 0·94, 95 % CI: 0·90, 0·98). Higher adherence to the MedDiet was associated with lower odds of MASLD and with reduced MASLD-related hospitalisations and mortality and lower all-cause mortality in those with MASLD. These findings support the role of MedDiet in reducing hepatic and cardiovascular burden in non-Mediterranean population.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"553-563"},"PeriodicalIF":3.1,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147763137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The association between dietary macronutrient distribution and mortality in an African cohort. 非洲队列中饮食宏量营养素分布与死亡率之间的关系。
IF 3.1 3区 医学
British Journal of Nutrition Pub Date : 2026-09-14 Epub Date: 2026-04-22 DOI: 10.1017/S000711452610717X
Marilize Linde, Carlien Van der Merwe, Cristian Ricci, Marlien Pieters
{"title":"The association between dietary macronutrient distribution and mortality in an African cohort.","authors":"Marilize Linde, Carlien Van der Merwe, Cristian Ricci, Marlien Pieters","doi":"10.1017/S000711452610717X","DOIUrl":"10.1017/S000711452610717X","url":null,"abstract":"<p><p>Optimal nutrition is essential for reducing both all-cause and CVD mortality. Existing research highlights the importance of macronutrient type and quality in this context, with limited evidence in non-Western populations. We aimed to determine the association between macronutrient distribution and all-cause and CVD mortality in an African population as well as the contribution of the respective food sources. This cohort consisted of 1737 African men and women with a median observational time of 13 years, resulting in 19 456·6 person-years. CVD-related international classification for diseases, 10th revision (ICD-10) codes (I00-I99) were included when considering CVD mortality. Substitution analysis using partition and nutrient-density models assessed the relationship between macronutrient distribution and mortality. Higher intakes of complex carbohydrates (CHO), animal protein, total fat and MUFA were associated with decreased all-cause mortality risk. The partition model also revealed that substituting 200 calories (kcal) of plant protein with animal protein significantly reduced all-cause mortality risk by 39 % to 33 % (model 1-3). In addition, the isoenergetic substitution of 10 % total energy from total fat with total CHO led to a 17 % reduction in all-cause mortality risk (hazard ratio (HR) 0·83; 95 % CI 0·72, 0·96). No significant associations with CVD mortality were found. These findings partially agree with, yet also oppose, previous studies, emphasising the need for population-specific data. Research from high-income European populations may not directly apply to African contexts due to food insecurity, reliance on staple-based diets with low-quality plant proteins and lean, higher-quality animal protein sources, as well as differences in CVD disease aetiology.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"572-582"},"PeriodicalIF":3.1,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147762314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between the nutritional risk index and stroke: evidence from National Health and Nutrition Examination Survey (NHANES) 2011-2020. 营养风险指数与中风之间的关系:来自NHANES 2011-2020的证据。
IF 3.1 3区 医学
British Journal of Nutrition Pub Date : 2026-09-14 Epub Date: 2026-04-24 DOI: 10.1017/S0007114526107181
Haiyan Jin, Jingfang Wu
{"title":"Association between the nutritional risk index and stroke: evidence from National Health and Nutrition Examination Survey (NHANES) 2011-2020.","authors":"Haiyan Jin, Jingfang Wu","doi":"10.1017/S0007114526107181","DOIUrl":"10.1017/S0007114526107181","url":null,"abstract":"<p><p>Using National Health and Nutrition Examination Survey data (2011-2020), we assessed the association between the nutritional risk index (NRI) and stroke risk among 22 839 adults (mean age, 49·61 (sd 17·07) years), including 910 individuals (3·98 %) with stroke. Weighted multivariable logistic regression and restricted cubic spline (RCS) analysis were used to characterise the association, with subgroup analyses to examine consistency across populations and mediation analyses to investigate the roles of lipid and inflammatory biomarkers. Higher continuous NRI was inversely associated with stroke, with each 1-unit increase associated with 4 % lower odds (OR = 0·96, 95 % CI: 0·95, 0·97), and participants in the highest NRI quartile (Q4) had a significantly lower stroke risk than those in the lowest NRI quartile (Q1) (OR 0·60, 95 % CI 0·42, 0·85). RCS analysis indicated a linear relationship (<i>P</i> for nonlinearity > 0·05), and the protective effect of higher NRI remained robust across nearly all subgroups examined. Mediation analyses revealed that total cholesterol, systemic immune-inflammation index, product of platelet and neutrophil count, neutrophil:lymphocyte ratio and lymphocyte:monocyte ratio each partially mediated the NRI-stroke association, with mediation effects ranging from 1·71 % to 13·65 %. These findings suggest that favourable nutritional status, reflected by higher NRI, is linked to lower stroke risk, with lipid metabolism and inflammation playing mediating roles in this association. Further longitudinal and mechanistic studies are warranted.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"583-591"},"PeriodicalIF":3.1,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147763099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of vitamin D on biochemical markers of osteoporosis: a meta-analysis of randomised trials. 维生素D对骨质疏松症生化指标的影响:随机试验的荟萃分析。
IF 3.1 3区 医学
British Journal of Nutrition Pub Date : 2026-09-14 Epub Date: 2026-04-27 DOI: 10.1017/S0007114526107193
Catherine S Alber, Jim Halsey, Jonathan Emberson, Harold Hin, Michael Hill, Jane Armitage, Robert J Clarke
{"title":"Effects of vitamin D on biochemical markers of osteoporosis: a meta-analysis of randomised trials.","authors":"Catherine S Alber, Jim Halsey, Jonathan Emberson, Harold Hin, Michael Hill, Jane Armitage, Robert J Clarke","doi":"10.1017/S0007114526107193","DOIUrl":"10.1017/S0007114526107193","url":null,"abstract":"<p><p>Plasma levels of procollagen type 1 N-propeptide (P1NP) and C-terminal telopeptide of type 1 collagen (CTX) are bone turnover markers (BTM) used to predict risk of fracture. We compared the effects of vitamin D supplements on plasma levels of P1NP and CTX in the Biochemical Efficacy and Safety Trial of vitamin D (BEST-D) trial (305 participants) after treatment with 2000 IU/d or 4000 IU/d vitamin D<sub>3</sub> or placebo. The results of BEST-D were combined in a meta-analysis of all trials of vitamin D <i>v</i>. placebo on levels of P1NP (12 trials, 2654 participants) or CTX (16 trials, 2695 participants). In BEST-D, allocation to vitamin D<sub>3</sub> resulted in a dose-dependent increase in 25-hydroxy-vitamin D (25(OH)D) levels but had no effects on P1NP or CTX. Geometric mean (se) levels at 12 months were similar for P1NP (41·7 (0·7) <i>v</i>. 42·9 (1·0) ng/ml; <i>P</i> = 0·29: either dose <i>v</i>. placebo) and likewise for CTX (0·23 (0·01) <i>v</i>. 0·23 (0·01) ng/ml; <i>P</i> = 0·98). In a meta-analysis of eighteen trials, the average difference between the within-trial change in P1NP for allocated vitamin D and control was -3·3 % (95 % CI -5·6, -1·0, <i>P</i> < 0·005). For CTX, this difference was slightly greater (-3·8 % (-6·8, -0·8); <i>P</i> = 0·01). There was no significant heterogeneity between these trials after stratifying trials with or without Ca, higher or lower doses of vitamin D, or lower <i>v</i>. higher pre-treatment levels of 25(OH)D. Overall, vitamin D supplementation was associated with modest reductions in both P1NP and CTX, and results provide support for further trials of vitamin D for prevention of fracture in older people.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"536-543"},"PeriodicalIF":3.1,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7619098/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147763087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patterns of dietary habits are associated with metabolic health status in adults. 成人饮食习惯模式与代谢健康状况相关。
IF 3.1 3区 医学
British Journal of Nutrition Pub Date : 2026-09-14 Epub Date: 2026-04-29 DOI: 10.1017/S0007114526106722
Arghavan Balali, Donya Poursalehi, Zahra Heidari, Parisa Rouhani, Farnaz Shahdadian, Zahra Hajhashemy, Sobhan Mohammdi, Elahe Mokhtari, Parvane Saneei
{"title":"Patterns of dietary habits are associated with metabolic health status in adults.","authors":"Arghavan Balali, Donya Poursalehi, Zahra Heidari, Parisa Rouhani, Farnaz Shahdadian, Zahra Hajhashemy, Sobhan Mohammdi, Elahe Mokhtari, Parvane Saneei","doi":"10.1017/S0007114526106722","DOIUrl":"10.1017/S0007114526106722","url":null,"abstract":"<p><p>Metabolic disorders have a detrimental effect on individuals' health status, regardless of their weight. We aimed to assess the link between diet-related behaviours and metabolic health status as well as serum levels of adropin and brain-derived neurotrophic factor (BDNF). A cross-sectional investigation involving 527 adults was conducted in Isfahan, Iran. Dietary habits were assessed in five domains including meal pattern, eating rate, meal-to-sleep interval, intra-meal fluid intake and fatty food intake. Based on the lipid and glycaemic profile, inflammation status and insulin resistance, participants were classified as having either metabolically healthy or metabolically unhealthy (MU) status. Serum concentrations of BDNF and adropin were also evaluated. Metabolic unhealthy normal-weight and overweight/obese status were prevalent in 8·7 % and 33·8 % of study population, respectively. We recognised three eating rate classes, two meal pattern classes, two meal-to-sleep interval classes, two intra-meal fluid intake classes, and two fatty food intake classes. Slow eating rate was related to lower odds of MU profile (OR = 0·39, 95 % CI: 0·17, 0·91). Moreover, fast eating rate was positively associated with hyperglycaemia (OR = 3·55, 95 % CI: 1·48, 8·51). More intra-meal fluid intake was also associated with higher chance of MU profile (OR = 2·21, 95 % CI: 1·35, 3·63), high homeostasis model assessment of insulin resistance (OR = 2·20, 95 % CI: 1·06, 4·58), hypertriglyceridaemia (OR = 2·23, 95 % CI: 1·36, 3·65) and hypertension (OR = 1·66, 95 % CI: 1·03, 2·69). Serum BDNF or adropin was not associated with classes of diet-related habits. More intra-meal fluid intake was linked to higher chance of having MU profile, while slow eating rate was related to decreased odds of MU profile among Iranian adults.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"505-522"},"PeriodicalIF":3.1,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147761315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Overall effectiveness of a school-based intervention in reducing adolescents' weight status and nutritional behaviours social inequalities. 以学校为基础的干预措施在减少青少年体重状况和营养行为方面的总体有效性。
IF 3.1 3区 医学
British Journal of Nutrition Pub Date : 2026-09-14 Epub Date: 2026-04-24 DOI: 10.1017/S0007114526107211
Arnaud Dosda, Johanne Langlois, Philip Böhme, Edith Lecomte, Karine Legrand, Elisabeth Spitz, Serge Briançon, Florian Manneville, Abdou Omorou
{"title":"Overall effectiveness of a school-based intervention in reducing adolescents' weight status and nutritional behaviours social inequalities.","authors":"Arnaud Dosda, Johanne Langlois, Philip Böhme, Edith Lecomte, Karine Legrand, Elisabeth Spitz, Serge Briançon, Florian Manneville, Abdou Omorou","doi":"10.1017/S0007114526107211","DOIUrl":"10.1017/S0007114526107211","url":null,"abstract":"<p><p>School-based interventions offer a promising setting to promote healthier nutritional behaviours (NB) such as physical activity (PA), sedentary behaviour (SB) and eating behaviour, while addressing weight social inequalities. NB changes may occur before measurable effects on weight, which can take longer to emerge. This study evaluated the overall effectiveness of the school-based Promotion de l'ALIMentation et de l'Activité Physique - INEgalités de Santé (PRALIMAP-INÈS) trial on weight and NB social inequalities reduction among adolescents with overweight or obesity. Adolescents were divided into two intervention groups according to their socio-economic status (socially advantaged and socially less advantaged). NB were self-reported by adolescents. Outcomes were BMI z-score (BMIz), fruit and vegetables (FV) consumption, sweetened products and beverages (SPB) consumption, vigorous/moderate PA, walking and SB. Overall effectiveness was estimated using generalised pairwise comparisons, estimating net benefit for each outcome (δ) and overall net benefit (Δ). Of 985 adolescents (age = 15·3 (sd 0·7 years; 46·7 % boys), those in less advantaged group were 12·5 % more likely to have a favourable change in weight status and NB than those in advantaged group (Δ = 12·5 % (6·1, 19·1 %)). For each outcome, net benefits were as follows: BMIz (δ = 4·2 % (0·0, 8·6)), vigorous PA (δ = 4·2 % (0·4, 8·3)), FV (δ = 3·2 % (0·9, 5·5)), SB (δ = 0·8 % (-1·6, 3·2)), SPB (δ = -0·2 % (-1·1, 0·6)), moderate PA (δ = 0·2 %) (-0·7, 1·1) and walking (δ = 0·2 % (-0·2, 0·6)). Results showed an overall beneficial effect of the PRALIMAP-INÈS trial in reducing social inequalities in weight and NB among adolescents with overweight or obesity. Long-term effectiveness could be expected by reducing social inequalities in NB.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"624-631"},"PeriodicalIF":3.1,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147763158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inequity on energy and nutrient consumption among urban residents of Ethiopia may impact the effectiveness of large-scale food fortification. 埃塞俄比亚城市居民的能量和营养消费不平等:对大规模食品强化有效性的影响。
IF 3.1 3区 医学
British Journal of Nutrition Pub Date : 2026-09-14 Epub Date: 2026-04-29 DOI: 10.1017/S0007114526107296
Semira Mitiku Saje, Louise Ander, Elaine L Ferguson, Dawd Gashu
{"title":"Inequity on energy and nutrient consumption among urban residents of Ethiopia may impact the effectiveness of large-scale food fortification.","authors":"Semira Mitiku Saje, Louise Ander, Elaine L Ferguson, Dawd Gashu","doi":"10.1017/S0007114526107296","DOIUrl":"10.1017/S0007114526107296","url":null,"abstract":"<p><p>Intra-household energy and nutrient inequity occur when food is distributed differentially, leaving some members without adequate nutrition. If unaddressed, this can reduce the effectiveness of food based nutrition interventions. This study assessed energy and micronutrient intake inequities among urban Ethiopian households before and after wheat flour and edible oil fortification. Using 24-h dietary recall data from the 2013 Ethiopian Household Food Consumption Survey, we analysed 375 households with adult men and women. The Ethiopian mandatory fortification standard for wheat flour and edible oil was considered in the simulation. Usual intake estimates and fortification modelling were performed using the Simulating Intake of Micronutrients for Policy Learning and Engagement macro 1-day method. Inequity ratios were calculated by comparing energy and nutrient intakes with dietary requirements for each group. Prefortification, the median nutrient consumption was generally higher among men, except for vitamin A. Fortification of wheat flour with Zn and vitamin B<sub>1</sub>, along with vitamin A-fortified vegetable oil, led to a 26-74 percentage point reduction in nutrient inadequacy among all participants. Men could benefit more from Zn and vitamin A fortification, whereas women could benefit more from vitamin B<sub>1</sub> fortification. Inequity estimates before and after fortification ranged from 1 to 1·5, favouring men. Although intra-household food allocation was not directly assessed, observed differences in nutrient intake between men and women suggest gender-related disparities that should be considered in nutrition interventions.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"607-612"},"PeriodicalIF":3.1,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13478756/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147763176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Leptin associations with body composition and lipid profile changes in women with overweight following dietary and exercise interventions. 饮食和运动干预后超重女性瘦素与身体组成和脂质变化的关系
IF 3.1 3区 医学
British Journal of Nutrition Pub Date : 2026-09-11 DOI: 10.1017/S0007114526108113
Fatemeh Bagherpour, Hamid Arazi, Hamid Rajabi, Bill I Campbell
{"title":"Leptin associations with body composition and lipid profile changes in women with overweight following dietary and exercise interventions.","authors":"Fatemeh Bagherpour, Hamid Arazi, Hamid Rajabi, Bill I Campbell","doi":"10.1017/S0007114526108113","DOIUrl":"https://doi.org/10.1017/S0007114526108113","url":null,"abstract":"<p><p>Leptin plays a key role in appetite regulation and fat metabolism, and its relationship with body fat compartments and lipid markers under different diet strategies remains unclear. This study aimed to evaluate how changes in leptin levels are associated with body composition and lipid profiles in overweight individuals engaged in resistance training (RT), across time-restricted eating (TRE) and high-protein consumption intervention groups. A total of thirty-two overweight women, aged 18 to 30 years, were randomly divided into four intervention groups: time-restricted eating with high-protein intake (THP), time-restricted eating with regular-protein intake (TRP), high protein without time restriction (HP) and regular protein without time restriction (RP). All participants engaged in RT and followed a diet with a 25 % caloric deficit for 8 weeks. Participants in the high-protein groups consumed 1·6 g/kg/d of protein, whereas those in the standard-protein groups consumed 0·8 g/kg/d. Significant positive associations between changes in leptin and fat mass (FM) were observed in the THP (<i>R</i><sup>2</sup> = 0·69, <i>P</i> = 0·01) and TRP (<i>R</i><sup>2</sup> = 0·53, <i>P</i> = 0·03) groups. In contrast, no significant associations were identified between leptin and visceral adipose tissue, or subcutaneous adipose tissue in any group. Associations between leptin and lipid markers varied across intervention groups, with significant relationships observed for TG in the THP group (<i>R</i><sup>2</sup> = 0·59, <i>P</i> = 0·02) and for LDL-cholesterol (<i>R</i><sup>2</sup> = 0·51, <i>P</i> = 0·04) and HDL-cholesterol (<i>R</i><sup>2</sup> = 0·63, <i>P</i> = 0·01) in the HP group. These findings suggest that changes in leptin are more closely associated with changes in total FM than with regional adipose tissue depots. Associations between leptin and lipid markers were less consistent across intervention groups, indicating that the relationship between leptin and metabolic outcomes may be influenced by dietary context. Findings should be interpreted cautiously given the exploratory nature of the analyses and the relatively small sample size.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-9"},"PeriodicalIF":3.1,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148929018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Daytime restricted feeding modifies the daily regulation of fatty acid β-oxidation and the lipoprotein profile in rats - CORRIGENDUM. 白天限制喂养改变了大鼠脂肪酸β氧化和脂蛋白谱的日常调节-勘误。
IF 3.1 3区 医学
British Journal of Nutrition Pub Date : 2026-09-10 DOI: 10.1017/S0007114526108381
J B Rivera-Zavala, C Molina-Aguilar, M Pérez-Mendoza, M Olguín-Martínez, R Hernández-Muñoz, G A Báez-Ruiz, M Díaz-Muñoz
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