British Journal of Nutrition最新文献_第4页

High dose fish oil supplements are more effective than oily fish in altering the number and function of extracellular vesicles in healthy human subjects: A randomized, double-blind, placebo-controlled, parallel trial. 在改变健康人细胞外囊泡的数量和功能方面，高剂量鱼油补充剂比油性鱼类更有效：随机、双盲、安慰剂对照、平行试验。

IF 3 3区医学

British Journal of Nutrition Pub Date : 2025-03-21 DOI: 10.1017/S0007114525000625

Amal Sharman, Ruihan Zhou, Jamie Pugh, Graeme Close, Helena L Fisk, Philip C Calder, Parveen Yaqoob

{"title":"High dose fish oil supplements are more effective than oily fish in altering the number and function of extracellular vesicles in healthy human subjects: A randomized, double-blind, placebo-controlled, parallel trial.","authors":"Amal Sharman, Ruihan Zhou, Jamie Pugh, Graeme Close, Helena L Fisk, Philip C Calder, Parveen Yaqoob","doi":"10.1017/S0007114525000625","DOIUrl":"https://doi.org/10.1017/S0007114525000625","url":null,"abstract":"N-3 polyunsaturated fatty acids (n-3 PUFAs) delivered by fish oil supplements alter the number and functions of circulating extracellular vesicles (EVs), but consumption of oily fish does not reproduce this effect. In order to assess the effects of fish oil supplements and oily fish, at a level achievable in the diet, on EV numbers, composition and procoagulant activity in healthy human volunteers, forty-two healthy subjects were assigned to one of three treatment groups: (i) fish oil supplements plus white fish meals, (ii) control supplements plus oily fish meals or (iii) control supplements plus white fish meals for 12 weeks in a randomized, double-blind, placebo-controlled, parallel trial; circulating EVs were enumerated and their procoagulant activity assessed using thrombin generation and fibrinolysis assays. Our results showed that fish oil supplements decreased circulating EV numbers and reduced EV-stimulated thrombin generation, but the consumption of oily fish at half the dose of EPA had no effect on either EV number or thrombogenic capacity. Consumption of both oily fish and fish oil supplements increased the EPA and DHA contents of EVs and the proportion of EPA in circulating EVs was strongly associated with EV-stimulated thrombin generation. This study revealed that the additional 1 g/d EPA delivered in the fish oil supplements is required to decrease the numbers and thrombogenic capacity of EVs, since oily fish at a level achievable in the diet had no effect. Increasing EPA intake beyond current guidelines for oily fish consumption may therefore be required for cardiovascular benefits relating to EVs.","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-32"},"PeriodicalIF":3.0,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Consumption of artificial sweeteners during pregnancy and the risk of overweight in the offspring. 孕期食用人造甜味剂与后代超重的风险

IF 3 3区医学

British Journal of Nutrition Pub Date : 2025-03-21 DOI: 10.1017/S0007114525000455

Eva M Gjørup, Bodil H Bech, Sofie Stampe, Thorhallur I Halldorsson, Anne A Bjerregaard, Sjurdur F Olsen, Per G Ovesen, Magnus Leth-Møller

{"title":"Consumption of artificial sweeteners during pregnancy and the risk of overweight in the offspring.","authors":"Eva M Gjørup, Bodil H Bech, Sofie Stampe, Thorhallur I Halldorsson, Anne A Bjerregaard, Sjurdur F Olsen, Per G Ovesen, Magnus Leth-Møller","doi":"10.1017/S0007114525000455","DOIUrl":"10.1017/S0007114525000455","url":null,"abstract":"Artificial sweeteners are used to reduce energy intake, but studies suggest that consumption during pregnancy may impact the offspring's risk of overweight. In this longitudinal cohort study, we aimed to examine the association between consumption of artificially sweetened or sugar-sweetened beverages during pregnancy and offspring overweight from birth to 18 years in the Danish National Birth Cohort. A total of 101 042 pregnancies were enrolled in the Danish National Birth Cohort from 1996 to 2002. Follow-up was conducted throughout pregnancy, childhood and adolescence. Additionally, 72 821 women completed an FFQ during pregnancy, reporting intake of beverages sweetened with artificial sweeteners or sugar. Offspring height and weight were obtained during childhood and adolescence. Multivariate logistic regression was performed to estimate the OR for overweight concerning maternal beverage consumption. Analyses were adjusted for risk factors for childhood overweight, including maternal age, pre-pregnancy BMI, physical activity and smoking in pregnancy, healthy eating index, paternal BMI, socio-economic status and duration of breastfeeding. We found increased odds of overweight in 7-, 11-, 14- and 18-year-old offspring whose mothers reported drinking ≥ 1 artificially sweetened beverage daily during pregnancy compared with no consumption (18 years: adjusted OR 1·26 (95 % CI 1·12, 1·42)). We found decreased adjusted odds of overweight in 11- and 18-year-old offspring whose mothers reported drinking ≥ 1 sugar-sweetened beverage daily during pregnancy compared with no consumption. We found that consumption of artificially sweetened beverages during pregnancy was associated with an increased risk of overweight in childhood and adolescence after adjustment for risk factors for childhood overweight.","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-11"},"PeriodicalIF":3.0,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reply to the letter to the editor 'The Role of Nutrition and Genetics in Thyroid Cancer Risk'. 回复致编辑的信《营养和遗传在甲状腺癌风险中的作用》。

IF 3 3区医学

British Journal of Nutrition Pub Date : 2025-03-19 DOI: 10.1017/S0007114524003258

Tao Thi Tran, Jeongseon Kim

引用次数: 0

Regional fat mass estimation using bioelectrical impedance analysis in healthy adults. 利用生物电阻抗分析估算健康成人的区域脂肪量。

IF 3 3区医学

British Journal of Nutrition Pub Date : 2025-03-19 DOI: 10.1017/S0007114525000510

Analiza M Silva, Tiago R Silva, Pedro B Júdice, Gil B Rosa, Ana V Bernardino, João P Magalhães, Inês R Correia, Megan Hetherington-Rauth, Luís B Sardinha

{"title":"Regional fat mass estimation using bioelectrical impedance analysis in healthy adults.","authors":"Analiza M Silva, Tiago R Silva, Pedro B Júdice, Gil B Rosa, Ana V Bernardino, João P Magalhães, Inês R Correia, Megan Hetherington-Rauth, Luís B Sardinha","doi":"10.1017/S0007114525000510","DOIUrl":"https://doi.org/10.1017/S0007114525000510","url":null,"abstract":"Whole-body and regional raw bioelectrical impedance analysis (BIA) parameters have been used to develop lean soft tissue estimation prediction models. Still, no regional fat mass (FM) assessment models have been provided. Hence, we aimed to develop and validate BIA-derived equations to predict regional FM against dual-energy X-ray absorptiometry (DXA) in healthy adults. One hundred and forty-eight adults (77 females) were included in this cross-sectional investigation. DXA assessed whole-body and regional FM, and raw bioelectrical parameters of distinct body regions were measured using a 50 kHz phase-sensitive BIA analyzer. BIA-derived equations were developed for each sex using a stepwise multiple linear regression approach in 2/3 of the sample and cross-validated in the remaining sample. The BIA-derived equations exhibited moderate to very strong relationships (p < 0.001) with DXA-measured FM of all body regions in females (r=0.650 to 0.907) and males (r=0.401 to 0.807). Also, for all the models, no significant deviation from linearity was found (p>0.10). Agreement analyses revealed no associations between the differences and the means of the predicted and DXA-derived FM. However, the limits of agreement were large, with individual errors exceeding 50% in females and 70% in males. While the new BIA-derived equations provide a valid estimate of regional FM in middle-aged healthy adults at the population level, demonstrating a cost-effective alternative to DXA for assessing regional FM, caution is advised when applying these equations for individual-level analysis.","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-22"},"PeriodicalIF":3.0,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A response to 'Carotid intima-media thickness measurement in children: is there any value to it?' 对“儿童颈动脉内膜-中膜厚度测量：有任何价值吗？”

IF 3 3区医学

British Journal of Nutrition Pub Date : 2025-03-19 DOI: 10.1017/S0007114525000558

Sabitha Sasidharan Pillai, M Vijayakumar, Ajitha Balakrishnan

引用次数: 0

Carotid intima-media thickness measurement in children: is there any value to it? 儿童颈动脉内膜-中膜厚度测量：有任何价值吗？

IF 3 3区医学

British Journal of Nutrition Pub Date : 2025-03-19 DOI: 10.1017/S0007114525000546

Christian Saleh, Hrvoje Budincevic

引用次数: 0

The role of nutrition and genetics in thyroid cancer risk. 营养和遗传在甲状腺癌风险中的作用。

IF 3 3区医学

British Journal of Nutrition Pub Date : 2025-03-19 DOI: 10.1017/S0007114524003246

Rikas Saputra, Yenni Lidyawati

引用次数: 0

Consumption of 'Moro' and 'Pera' orange juices does not increase glycaemic and insulinaemic responses to other foods in adults. 饮用“Moro”和“Pera”橙汁不会增加成年人对其他食物的血糖和胰岛素反应。

IF 3 3区医学

British Journal of Nutrition Pub Date : 2025-03-17 DOI: 10.1017/S0007114525000418

Eliana Bistriche Giuntini, Layanne Nascimento Fraga, Isabella de Araújo Esteves Duarte, Felipe Rebello Lourenço, Neuza Mariko Aymoto Hassimotto, Franco Maria Lajolo

{"title":"Consumption of 'Moro' and 'Pera' orange juices does not increase glycaemic and insulinaemic responses to other foods in adults.","authors":"Eliana Bistriche Giuntini, Layanne Nascimento Fraga, Isabella de Araújo Esteves Duarte, Felipe Rebello Lourenço, Neuza Mariko Aymoto Hassimotto, Franco Maria Lajolo","doi":"10.1017/S0007114525000418","DOIUrl":"10.1017/S0007114525000418","url":null,"abstract":"There has been concern regarding the consumption of fruit juices because of the high levels of naturally occurring sugars they contain, which could rapidly elevate glycaemic response and increase the risk of cardiometabolic diseases. We conducted two trials in which each volunteer ingested (1) white bread with 200 ml of two types of orange juice (OJ) prepared from 'Moro' and 'Pera' varieties (MOJ and POJ) - the former containing anthocyanins - and the same juices alone; and (2) 200 ml of POJ or MOJ followed by a sandwich made with white bread, plus light cheese or butter, and also the same juices alone. Capillary blood was collected over 120 min, and glucose and insulin levels were analysed. In the cross-over clinical design with healthy volunteers, we observed that both OJ does not increase blood glucose and insulin, even when co-consumed with other typical breakfast foods in Brazil. In conclusion, OJ does not elevate postprandial glycaemic responses to the meal while providing additional sugars and nutrients.","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-8"},"PeriodicalIF":3.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Longitudinal associations of diet quality with serum biomarkers of lipid and amino acid metabolism from childhood to adolescence: the PANIC study. 儿童期至青春期饮食质量与血清脂质和氨基酸代谢生物标志物的纵向关联：PANIC研究。

IF 3 3区医学

British Journal of Nutrition Pub Date : 2025-03-14 DOI: 10.1017/S0007114525000492

Suvi E Laamanen, Saara Heinonen, Eero A Haapala, Ursula Schwab, Sonja Soininen, Taisa Sallinen, Aino-Maija Eloranta, Timo A Lakka

{"title":"Longitudinal associations of diet quality with serum biomarkers of lipid and amino acid metabolism from childhood to adolescence: the PANIC study.","authors":"Suvi E Laamanen, Saara Heinonen, Eero A Haapala, Ursula Schwab, Sonja Soininen, Taisa Sallinen, Aino-Maija Eloranta, Timo A Lakka","doi":"10.1017/S0007114525000492","DOIUrl":"https://doi.org/10.1017/S0007114525000492","url":null,"abstract":"Studies on longitudinal associations between diet quality and lipid and amino acid metabolism in children and adolescents are limited. We studied associations between diet quality and serum markers of lipid and amino acid metabolism in the Physical Activity and Nutrition in Children (PANIC) study. These analyses included 403 children aged 6-9 years at baseline, 360 re-examined two years later at age 9-11 years, and 219 eight years later at age 15-17 years. Food intake was recorded over four days, and diet quality assessed using the Finnish Children Healthy Eating Index (FCHEI). Fasting serum fatty acids, amino acids, apolipoproteins, and lipoprotein particle sizes were analyzed via nuclear magnetic resonance spectroscopy. Linear mixed-effects models, adjusted for sex, age, body fat percentage, pubertal stage, and physical activity, were used to analyze the associations. Better diet quality was linked to increased serum polyunsaturated fatty acids and reduced saturated and monounsaturated fatty acids, alanine and very low-density lipoprotein (VLDL) particle size. Consuming more vegetables, fruits, berries, vegetable oils and margarine with at least 60% fat, fish, and whole grains associated with higher serum polyunsaturated fatty acids and lower saturated fatty acids and smaller VLDL particles. Conversely, consuming higher-fat dairy products and sugary products associated with higher saturated and monounsaturated fatty acids, branched-chain and aromatic amino acids, and larger VLDL particles. A diet rich in fruits, vegetables, unsaturated fats, and fiber, with reduced processed meat and sugar consumption, promotes favorable metabolic changes relevant to cardiometabolic health.","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-43"},"PeriodicalIF":3.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association Between Body Fat Percentage and Urinary Flow Rate in US Adults: Analysis of the National Health and Nutrition Examination Survey 2011-2018. 美国成年人体脂百分比与尿流率之间的关系：2011-2018年国家健康与营养调查分析

IF 3 3区医学

British Journal of Nutrition Pub Date : 2025-03-13 DOI: 10.1017/S000711452500039X

Xiao Jin, WuQi Mi, ZhaoHua Ye, ShaoWei Fang, RuJun Mo, XinJie Luo, ZhengGuo Cao

{"title":"Association Between Body Fat Percentage and Urinary Flow Rate in US Adults: Analysis of the National Health and Nutrition Examination Survey 2011-2018.","authors":"Xiao Jin, WuQi Mi, ZhaoHua Ye, ShaoWei Fang, RuJun Mo, XinJie Luo, ZhengGuo Cao","doi":"10.1017/S000711452500039X","DOIUrl":"https://doi.org/10.1017/S000711452500039X","url":null,"abstract":"To assess the relationship between total body fat percentage(TBFP), trunk fat percentage(TFP), and urinary flow rate(UFR).We stratified by age and sex and hypothesize that TBFP and TFP are negatively associated with UFR across all groups.The study utilized data from the National Health and Nutrition Examination Survey (NHANES), which includes a series of nationally representative cross-sectional surveys. The data analyzed in this study included 18-59-year-old females and males who participated in the NHANES surveys conducted between 2011 and 2018. Multivariable-adjusted logistic regression models were used to examine the association between body fat percentages measured by dual-energy X-ray absorptiometry (DXA) scans and UFR.A total of 10,521 participants were included and an increase in total body fat percentage(TBFP) was inversely associated with in UFR (β= -0.013,95% confidence interval[CI]-0.018 to -0.007), Similarly,an increase in trunk fat percentage(TFP)was inversely associated with UFR(β=-0.014,95%CI-0.018 to -0.009).Stratified analyses by gender revealed that among males, an increase in TBFP and TFP was inversely associated with in UFR (β=-0.011, 95% CI -0.019 to -0.004; β=-0.016, 95% CI -0.022 to -0.009), although this association was not observed in the 18-35 age group. Among females, an increase in TBFP and TFP was inversely associated with UFR (β= -0.016, 95% CI -0.023 to -0.008; β= -0.012, 95% CI -0.019 to -0.006), and this association was observed across all age groups.Our study shows that in the population aged 18 to 59, both total body fat and truncal fat accumulation are inversely associated with urinary flow rate. However, the association in males under 35 is not significant. Future research should delve into the mechanisms behind these gender and age differences to provide a more precise basis for developing targeted prevention and intervention measures.","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-22"},"PeriodicalIF":3.0,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143613465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0