British Journal of Nutrition最新文献

{"title":"Diet's total antioxidant capacity and women's health: systematic review and meta-analysis.","authors":"Tauane A Dutra, Marilene B T Fragoso, Thiago M Wanderley, Alexandra R Bezerra, Nassib B Bueno, Alane C M de Oliveira","doi":"10.1017/S0007114525000443","DOIUrl":"https://doi.org/10.1017/S0007114525000443","url":null,"abstract":"<p><p>The primary causes of female mortality often involve diseases related to oxidative stress. Dietary total antioxidant capacity (TAC) evaluates its antioxidant content and potential health effects. This study, registered with PROSPERO (ID: CRD42024427784), explores the association between dietary TAC and women's health outcomes, including endocrine conditions with gynecological implications, obstetric outcomes, gynecological conditions, and oncological diseases related to the female reproductive system. We conducted a systematic search in MEDLINE (via PubMed), EMBASE, LILACS, and CINAHL for observational studies published up to February 2024 that explored the relationship between dietary TAC and these health conditions. Data were analyzed using RevMan 5.4 software. Nineteen studies met the eligibility criteria (sample sizes: 64 to 3,209 women) and examined various conditions, including neoplasms (breast, endometrial, and ovarian), bacterial vaginosis, menopause, polycystic ovary syndrome (PCOS), pre-eclampsia (PE), gestational diabetes mellitus (GDM), miscarriage, infertility, and inflammation and oxidative stress markers. The meta-analysis identified a significant association between dietary total antioxidant capacity (TAC), measured in vitamin C equivalents, and breast cancer, revealing that women with the disease had a lower dietary TAC due to reduced antioxidant intake. Mixed results were found for endometrial cancer, while higher TAC levels were associated with a lower risk of PCOS and infertility. Among postmenopausal women, higher TAC correlated with fewer symptoms such as sleep issues and anxiety. In gestational conditions, higher dietary TAC was linked to a lower risk of miscarriage, GDM, and PE. Twelve of the nineteen studies demonstrated significant associations between dietary TAC and the outcomes of interest.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-29"},"PeriodicalIF":3.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143566185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association of the dietary advanced glycation end products with functional gastrointestinal disorders: The Isfahan functional disorders (ISFUN) cohort study.","authors":"Fahimeh Haghighatdoost, Awat Feizi, Tiffany K Gill, Parisa Hajihashemi, Hassan Shahoon, Alireza Ani, Hamidreza Roohafza, Peyman Adibi","doi":"10.1017/S0007114525000388","DOIUrl":"https://doi.org/10.1017/S0007114525000388","url":null,"abstract":"<p><p>High intake of dietary advanced glycation end products (AGEs), could induce oxidative stress, inflammation, and the gut microbiota dysbiosis, processes that play a major role in the development of functional gastrointestinal disorders (FGIDs). There is limited data on the association between AGEs intake and FGIDs. Therefore, the current study aimed to examine the association of AGEs with FGIDs in Iranian adults. In a cross-sectional analysis under the framework of the Isfahan functional disorders (ISFUN) study, data on 1892 Iranian apparently healthy adults, aged 18 to 65 years were examined. Participants' dietary intakes were collected using a validated dish-based, 106- item food frequency questionnaire. Dietary AGEs content of 72 food items were measured for all participants. FGIDs was assessed using ROME IV criteria. In total, 38% of subjects had one of the most prevalent upper or lower FGIDs. The mean of AGEs intake was 14690.10±8797.25 (kU/gr). In the fully adjusted model, being in the highest versus lowest tertile of AGEs intake was associated with increased odds of FGIDs (OR= 1.78; 95% CI: 1.01, 3.36). In stratified analysis by sex, males in the highest tertile of AGEs intake showed higher odds of FGIDs than those in the lowest tertile (OR= 2.15; 95% CI: 1.04, 4.45). However, in females, the AGEs intake was not significantly associated with the risk of FGIDs in the fully adjusted model. Higher AGEs intake was significantly associated with increased risk of FGIDs, particularly in men. Further prospective studies are warranted to confirm these findings.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-22"},"PeriodicalIF":3.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-sectional associations between healthy and unhealthy plant-based diets and metabolic syndrome in three distinct French populations, a meta-analysis.","authors":"Clémentine Prioux, Sandra Wagner, Léopold K Fézeu, Valérie Deschamps, Charlotte Verdot, Julia Baudry, Mathilde Touvier, Serge Herberg, Julie-Anne Nazare, Axelle Hoge, Joao Pedro Ferreira, Patrick Rossignol, Nicolas Girerd, Sopio Tatulashvili, Emmanuelle Kesse-Guyot, Benjamin Allès","doi":"10.1017/S0007114525000376","DOIUrl":"https://doi.org/10.1017/S0007114525000376","url":null,"abstract":"<p><p>Prior studies have shown that plant-based diets are associated with lower cardiovascular risk. However, these diets encompass a large diversity of foods with contrasted nutritional quality that may differentially impact health. We aimed to investigate the pooled cross-sectional association between metabolic syndrome (MetS), its components, and healthy and unhealthy plant-based diet indices (hPDI and uPDI), using data from two French cohorts and one representative study from the French population. This study included 16,358 participants from the NutriNet-Santé study, 1,769 participants from the Esteban study and 1,565 participants from the STANISLAS study who underwent a clinical visit. The MetS was defined according to the International Diabetes Federation definition. The associations between these plant-based diet indices and MetS were estimated by multivariable Poisson and logistic regression models, stratified by gender. Meta-analysis enabled the computation of a pooled Prevalence Ratio. A higher contribution of healthy plant foods (higher hPDI) was associated with a lower probability of having MetS (PR_men: 0.85; 95% CI: 0.75-0.94, PR_women: 0.72; 95% CI: 0.67-0.77), elevated waist circumferences and elevated blood pressure. In women, a higher hPDI was associated with a lower probability of having elevated triglycerides, low HDL-cholesterolemia and hyperglycemia; and a higher contribution of unhealthy plant foods was associated with a higher prevalence of MetS (PR_women: 1.13; 95% CI: 1.01-1.26) and elevated triglycerides. A greater contribution of healthy plant floods was associated with protective effects on metabolic syndrome, especially in women. Gender differences should be further investigated in relation to the current sustainable nutrition transition.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-48"},"PeriodicalIF":3.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association of cognitive task scores with energy intake measurement error from technology-assisted 24-h recalls.","authors":"Clare Whitton, Barbara A Mullan, Satvinder S Dhaliwal, Richard Norman, Carol J Boushey, Clare E Collins, Megan E Rollo, Deborah A Kerr","doi":"10.1017/S000711452500042X","DOIUrl":"10.1017/S000711452500042X","url":null,"abstract":"<p><p>Measurement error undermines the accuracy of dietary intake data. The 24-h dietary recall (24HR) is the standard data collection method in nutrition surveillance. Several neurocognitive processes underpin the act of recall, and individuals differ in their performance of these processes. This study aimed to investigate whether variation in neurocognitive processes, measured using four cognitive tasks, was associated with variation in measurement error of 24HR. Participants (<i>n</i> 139) completed the Trail Making Test, the Wisconsin Card Sorting Test, the Visual Digit Span and the Vividness of Visual Imagery questionnaire. During a controlled feeding study, participants completed three technology-assisted 24HR: the Automated Self-Administered Dietary Assessment Tool, Intake24 and an Interviewer-Administered Image-Assisted 24HR (IA-24HR) 1 week apart. The percentage error between reported and true energy intakes was calculated. Using linear regression, the association between cognitive task scores and absolute percentage error in estimated energy intake was assessed. Longer time spent completing the Trail Making Test, an indicator of visual attention and executive functioning, was associated with greater error in energy intake estimation using ASA24 (B 0·13, 95 % CI 0·04, 0·21) and Intake24 (B 0·10, 95 % CI 0·02, 0·19). Regression models explained 13·6 % (ASA24) and 15·8 % (Intake24) of the variance in energy estimation error. No cognitive task scores were associated with error using IA-24HR. This study demonstrates that variation between individuals in neurocognitive processes explains some of the variation in 24HR error. Further investigation into the role of neurocognitive processes in 24HR and their role in the reliability of dietary intake data is warranted.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-10"},"PeriodicalIF":3.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutrient intake variability and number of days needed to estimate usual intake in children and adolescents with autism spectrum disorder.","authors":"Eduarda Silva, Laura Hoffmann, Kamila Castro, Eliseu Verly Junior, Sandra Valle, Juliana S Vaz","doi":"10.1017/S0007114525000200","DOIUrl":"10.1017/S0007114525000200","url":null,"abstract":"<p><p>Children and adolescents diagnosed with autism spectrum disorder (ASD) present feeding problems that may influence food acceptance and refusal. However, data regarding dietary intake variability in this population are either not available in the literature or not well-known. This cross-sectional study aimed to identify the within-person and between-person variability, and the number of days needed for a 24-hour recall (24HR) to estimate the usual intake of children and adolescents with ASD. Data were collected from 284 patients assisted at a public neuropediatric health service in the city of Pelotas, Southern Brazil. Food consumption was assessed using three non-consecutive 24HR. Within-person (S²_w) and between-person (S²_b) variances, the variance ratio (VR) and the distribution of energy, macronutrients and micronutrients were obtained using the Multiple Source Method® (version 1.0.1). The number of days of 24HR needed was calculated for correlation coefficients of 0·7, 0·8 and 0·9. For most nutrients, S²_w was greater than S²_b, resulting in VR > 1, except for age-group analyses where children up to 5 years old showed VR < 1. Two to three days of 24HR were estimated for most nutrients, considering a correlation coefficient of 0·8. Differences were observed according to sex and age group, with adolescents requiring more days of 24HR. These findings indicate the need to assess dietary variability among individuals with ASD according to the characteristics of this investigated population.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-10"},"PeriodicalIF":3.0,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the Association Between the Mediterranean, DASH, and MIND Dietary Patterns, Structural Connectivity, and Cognitive Function.","authors":"Lizanne Arnoldy, Sarah Gauci, Lauren M Young, Helen Macpherson, Oren Civier, Andrew Scholey, Andrew Pipingas, David J White","doi":"10.1017/S0007114525000406","DOIUrl":"https://doi.org/10.1017/S0007114525000406","url":null,"abstract":"<p><p>The rising incidence of neurodegenerative diseases in an ageing global population has shifted research focus toward modifiable risk factors, such as diet. Despite potential links between dietary patterns and brain health, inconsistencies in neuroimaging outcomes underscore a gap in understanding how diet impacts brain ageing. This study explores the relationship between three dietary patterns-Mediterranean (MeDi), Dietary Approaches to Stop Hypertension (DASH), and Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND)-and cognitive outcomes as well as brain connectivity. The study aimed to assess the association of these diets with brain structure and cognitive function, involving a middle-aged healthy group and an older cohort with subjective cognitive decline (SCD). The study included cognitive assessments and diffusion-weighted MRI data to analyse white matter microstructural integrity. Participants comprised 55 older individuals with SCD (54.5% female, mean age = 64) and 52 healthy middle-aged individuals (48.1% female, mean age = 53). Age inversely correlated with certain cognitive functions and global brain metrics, across both cohorts. Adherence to the MeDi, DASH, and MIND diets showed no significant cognitive or global brain metric improvements after adjusting for covariates (age, education, BMI). Network-based statistics (NBS) analysis revealed differences in brain subnetworks based on DASH diet adherence levels in the SCD cohort. In the healthy cohort, lower white matter connectivity was associated with reduced adherence to MIND and DASH diets. Ultimately, the study found no strong evidence connecting dietary patterns to cognitive or brain connectivity outcomes. Future research should focus on longitudinal studies and refine dietary assessments.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-49"},"PeriodicalIF":3.0,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased costs associated with greater adherence to the EAT-Lancet Commission reference diet in the province of Québec: the PREDISE Study.","authors":"Gabrielle Rochefort, Marie-Claude Paquette, Julie Robitaille, Simone Lemieux, Véronique Provencher, Benoît Lamarche","doi":"10.1017/S0007114525000364","DOIUrl":"10.1017/S0007114525000364","url":null,"abstract":"<p><p>The diet proposed by the EAT-Lancet Commission has faced criticism concerning its affordability. This study aimed to investigate the cost associated with a greater alignment to the EAT-Lancet reference diet in the province of Québec, Canada. The dietary habits of 1147 French-speaking adults were assessed using repeated web-based 24-h recall data collected between 2015 and 2017 in the cross-sectional PRÉDicteurs Individuels, Sociaux et Environnementaux (PREDISE) study. Diet costs were calculated using a Nielsen food price database. Usual dietary intakes and diet costs were estimated using the National Cancer Institute's multivariate Markov Chain Monte Carlo method. Adherence to the EAT-Lancet diet was assessed using the EAT-Lancet dietary index (EAT-I). Associations between diet costs and EAT-I scores were evaluated using linear regression models with restricted cubic splines. After adjustment for energy intake, a higher EAT-I score (75th <i>v</i>. 25th percentiles) was associated with a 1·0 $CAD increase in daily diet costs (95 % CI, 0·7, 1·3). This increase in diet costs was mostly driven by the following component scores of the EAT-I (75th <i>v</i>. 25th percentiles, higher scores reflecting greater adherence): vegetables (1·6 $CAD/d, 95 % CI: 1·2, 2·1), free sugars (1·6 $CAD/d, 95 % CI: 1·3, 1·9), fish and plant-based proteins (1·4 $CAD/d, 95 % CI: 1·0, 1·8), fruits (0·9 $CAD/d, 95 % CI: 0·4, 1·3) and whole grains (0·4 $CAD/d, 95 % CI: 0·0, 0·8). Inversely, a greater score for the poultry and eggs component was associated with reduced diet costs (-1·2 $CAD/d, 95 % CI: -1·7, -0·7). This study suggests that adhering to the EAT-Lancet diet may be associated with an increase in diet costs in the province of Québec.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-8"},"PeriodicalIF":3.0,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beneficial effects of okra (<i>Abelmoschus esculentus</i> L.) consumption on anthropometric measures, blood pressure, glycaemic control, lipid profile and liver function tests in randomised controlled trials: a GRADE-assessed systematic review and dose-response meta-analysis.","authors":"Ali Jafari, Helia Mardani, Bahare Parsi Nezhad, Alireza Alaghi, Amirhossein Sahebkar","doi":"10.1017/S0007114525000303","DOIUrl":"10.1017/S0007114525000303","url":null,"abstract":"<p><p>This review aimed to assess the impact of okra (<i>Abelmoschus esculentus</i> L.) consumption on CVD risk factors. Relevant studies were identified through electronic searches of databases, including PubMed, Scopus, Web of Science, CENTRAL and EMBASE, up to January 2025. Twelve trials involving 770 participants with interventions ranging from 2 to 12 weeks and doses varying from 125 to 40 000 mg/d were included. Okra supplementation significantly reduced BMI (standardised mean difference (SMD) = -0·70; 95 % CI -1·23, -0·16; <i>P</i> = 0·011), fat mass (SMD = -0·74; 95 % CI -1·13, -0·36; <i>P</i> < 0·001), hip circumference (SMD = -0·85; 95 % CI -1·41, -0·28; <i>P</i> = 0·003), weight (SMD = -0·77; 95 % CI -1·42, -0·11; <i>P</i> = 0·022), fasting insulin (SMD = -0·35; 95 % CI -0·63, -0·07; <i>P</i> = 0·013), fasting plasma glucose (SMD = -1·07; 95 % CI -1·75, -0·38; <i>P</i> = 0·002), HbA1c (SMD = -0·38; 95 % CI -0·71, -0·05; <i>P</i> = 0·023), homeostatic model assessment of insulin resistance (SMD = -0·56; 95 % CI -0·84, -0·29; <i>P</i> < 0·001), LDL-cholesterol (SMD = -0·32; 95 % CI -0·52, -0·11; <i>P</i> = 0·003), total cholesterol (SMD = -0·45; 95 % CI -0·74, -0·16; <i>P</i> = 0·003) and aspartate aminotransferase (SMD = -0·45; 95 % CI -0·73, -0·17; <i>P</i> = 0·002). Okra supplementation demonstrated significant benefits in improving anthropometric measures, glycaemic control, lipid profiles and liver function tests, suggesting its potential as an adjunct therapy for improving CVD risk factors.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-28"},"PeriodicalIF":3.0,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143499456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations of subjective sleep patterns and social jet lag with weight loss and dietary intake in bariatric surgery patients: a 1-year follow-up study.","authors":"Aline Cunha Carvalho, Luisa Pereira Marot, Luis Augusto Mattar, José Américo Gomides de Sousa, Ana Cristina Tomaz Araújo, Camila Thais da Costa Assis, Maria Carliana Mota, Cibele Aparecida Crispim","doi":"10.1017/S0007114525000352","DOIUrl":"10.1017/S0007114525000352","url":null,"abstract":"<p><p>Current literature has shown that poor sleep patterns and social jet lag (SJL) are associated with obesity and weight gain. However, this area remains underexplored in patients who have undergone bariatric surgery. We hypothesised that higher levels of SJL and poorer sleep patterns are associated with lower weight loss, greater caloric/nutrient intake and poorer metabolic outcomes following surgery. This study aims to assess the associations of SJL and subjective sleep with anthropometric, metabolic and dietary parameters during the first year following bariatric surgery. SJL, sleep quality and daytime sleepiness were measured in 122 patients (77 % women; median age 33·0 [28·0 - 41·7]). SJL was estimated by the absolute difference between the midpoint of sleep and wake times on weekdays and weekends. Daytime sleepiness and sleep quality were evaluated using the Epworth Sleepiness Scale (Epworth) and the Pittsburgh Sleep Quality Index, respectively. Multiple linear regressions were employed to evaluate the associations of SJL, sleep quality and daytime sleepiness with weight loss, metabolic and dietary outcomes. Independent variables were negatively associated with weight loss after surgery: SJL at 6 months and 1 year; sleep quality at all time points and sleepiness after one year (<i>P</i> < 0·05). SJL was positively associated with calorie and protein intake after 1-year post-surgery (<i>P</i> < 0·05). Our results show that higher SJL and poorer sleep patterns are associated with worse anthropometric, metabolic and dietary outcomes after bariatric surgery. These findings reinforce the importance of addressing variables related to biological rhythms to optimise post-surgical outcomes in bariatric patients.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-10"},"PeriodicalIF":3.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diet, Glutathione S-Transferases M1 and T1 Gene Polymorphisms and Cancer Risk: A Systematic Review of Observational Studies.","authors":"Elham Karimi, Shalaleh Abbasnezhad, Sheida Zeraattalab-Motlagh, Reza Amiri Khosroshahi, Seyed Reza Beh-Afarin, Hamed Mohammadi, Marjan Yaghmaie","doi":"10.1017/S0007114525000327","DOIUrl":"https://doi.org/10.1017/S0007114525000327","url":null,"abstract":"<p><p>Understanding the correlation between genes and diet holds significance in formulating tailored nutritional guidance and enhancing public health initiatives. Consequently, a thorough examination is undertaken to clarify the interplay between varying nutrient intake, Glutathione S-transferases Mu1 and Theta 1 (GSTM1 & T1) gene variants, and susceptibility to cancer development. In this study, we conducted a comprehensive search on MEDLINE/PubMed, Scopus, and Web of Science databases up to April 30, 2023. The review included observational studies that explored the relationship between dietary consumption of acrylamide, fruits, vegetables, plant-based foods, total meat, red meat, coffee, and green tea, as well as the presence of GSTM1 and T1 gene polymorphisms, and the risk of cancer in adult populations. The review findings indicated that high levels of risk factors, particularly red meat, have been linked to a higher chance of developing colorectal cancer risk among individuals with the GSTM1 null genotype. In contrast, heightened levels of protective factors, such as cruciferous vegetables, green tea, coffee, and fruit, have been associated with a decreased risk of lung cancer, adult leukemia, cutaneous melanoma, and lung cancer in individuals exhibiting GST polymorphisms. There is a scarcity of comprehensive studies examining different types of cancer due to various dietary patterns and genetic variations. Research has illuminated the complex interplay among dietary factors, gene polymorphisms, and cancer risk, further comprehensive studies are needed to understand and validate these findings fully. More robust investigations across diverse populations are crucial to developing personalized nutritional interventions and strengthening public health strategies.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-35"},"PeriodicalIF":3.0,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143466983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}