British Journal of Nutrition最新文献

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Impact of creatine monohydrate supplementation combined with multicomponent training in older adults (≥75 years): study protocol of a randomized controlled trial. 补充一水肌酸联合多组分训练对老年人(≥75岁)的影响:一项随机对照试验的研究方案
IF 3 3区 医学
British Journal of Nutrition Pub Date : 2026-05-07 DOI: 10.1017/S0007114526107302
M L Fernández-González de la Riva, F Zambom-Ferraresi, F Zambom-Ferraresi, M Izco-Cubero, P Álvarez-Rodríguez, A Zugasti-Murillo, I Echeverría-Beistegui, B A Cedeño-Veloz, D Marcos-Pérez, A Capón-Sáez, D Moral-Cuesta, N Soto-Ruiz, N Martínez-Velilla
{"title":"Impact of creatine monohydrate supplementation combined with multicomponent training in older adults (≥75 years): study protocol of a randomized controlled trial.","authors":"M L Fernández-González de la Riva, F Zambom-Ferraresi, F Zambom-Ferraresi, M Izco-Cubero, P Álvarez-Rodríguez, A Zugasti-Murillo, I Echeverría-Beistegui, B A Cedeño-Veloz, D Marcos-Pérez, A Capón-Sáez, D Moral-Cuesta, N Soto-Ruiz, N Martínez-Velilla","doi":"10.1017/S0007114526107302","DOIUrl":"https://doi.org/10.1017/S0007114526107302","url":null,"abstract":"<p><p>Creatine monohydrate is a widely used supplement to improve physical performance and strength. Recent studies suggest it may also benefit cognitive function and depression treatment. However, data on its effects in older adults are scarce, highlighting the need for further research in this population. This study is a randomized, double-blind, placebo-controlled trial assessing five weeks of creatine monohydrate (CrM) supplementation combined with physical training in older adults (≥75 years). Participants will be divided into four groups: placebo (PL), placebo with multicomponent training (PL + MT), creatine monohydrate supplementation (CrM), and creatine monohydrate with multicomponent training (CrM + MT). Evaluations will be conducted before, during, and after the intervention, and again after a five-week washout period. The training program includes supervised sessions twice a week over four weeks, focusing on resistance, cardiovascular, balance, reaction, and agility exercises. Functional capacity and fall risk will be measured, alongside physical tests such as handgrip strength and one-repetition maximum (1RM) tests for leg press, bench press, seated row, and leg extension. Cognitive and emotional assessments will also be conducted during the intervention. The results of this study aim to increase our understanding of the effects of CrM supplementation in older adults. This study is expected to generate valuable information on the impact and safety of this nutrition and exercise strategy, and its application can be extended to a variety of health conditions.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-32"},"PeriodicalIF":3.0,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147833973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of lifestyle and genetic susceptibility factors with body composition and fat distribution among women. 生活方式和遗传易感性因素与女性身体组成和脂肪分布的关系。
IF 3 3区 医学
British Journal of Nutrition Pub Date : 2026-05-07 DOI: 10.1017/S0007114526107429
Huan Liu, Chenhui Zhang, Shanshan Zhang, Qian Shen, Siyue Wang, Pengcheng Liu, Cong Zhang, Qing Wang, Xiangli Chen, Ying Qu, Rongcheng Huang, Jiang Chang, Li Liu, Xiaohua Chen, Rong Zhong
{"title":"Association of lifestyle and genetic susceptibility factors with body composition and fat distribution among women.","authors":"Huan Liu, Chenhui Zhang, Shanshan Zhang, Qian Shen, Siyue Wang, Pengcheng Liu, Cong Zhang, Qing Wang, Xiangli Chen, Ying Qu, Rongcheng Huang, Jiang Chang, Li Liu, Xiaohua Chen, Rong Zhong","doi":"10.1017/S0007114526107429","DOIUrl":"https://doi.org/10.1017/S0007114526107429","url":null,"abstract":"<p><p>Body composition and fat distribution were found to display differential effects on the incidence and mortality of chronic disease. However, it remained unclear whether there is an interaction between lifestyle factors and genetic susceptibility on body composition and fat distribution. This study investigated the associations of lifestyle and genetic factors with body composition and fat distribution among 121,664 women from the UK Biobank cohort study. Women with a favorable lifestyle had lower body mass index (BMI, -7.72% [95% CI: -7.93%, -7.51%]), fat mass index (FMI, -15.70% [95% CI: -16.09%, -15.30%]), fat-free mass index (FFMI, -2.86% [95% CI: -2.98%, -2.74%]), arm fat ratio (AFR, -5.19%, [95% CI: -5.38%, -5.00%]), and trunk fat ratio (TFR, -0.73%, [95% CI: -0.84%, -0.62%]), but higher leg fat ratio (LFR, 2.30% [95% CI: 2.16%, 2.44%]) than those with an unfavorable lifestyle. Significant interactions between lifestyle factors and genetic susceptibility on BMI, FMI, and AFR were observed (<i>P</i><sub>interaction</sub> < 0.05). Among women with a high genetic susceptibility to body composition or fat distribution, those with a healthy lifestyle still had a lower BMI, FMI, FFMI, AFR, and TFR, and higher LFR (<i>P</i><sub>trend</sub> < 0.001). Women who adhere to a favorable lifestyle tend to have healthy body composition and fat distribution and this association is consistent across all strata of genetic risk.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-23"},"PeriodicalIF":3.0,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differing Normative Reference Ranges for Body Composition and Physical Performance measures in Hong Kong Chinese and Canadian Older Adults: The Hong Kong Os Study and the Canadian Longitudinal Study on Aging. 香港华人和加拿大老年人身体成分和体能测量的不同标准参考范围:香港Os研究和加拿大老龄化纵向研究。
IF 3 3区 医学
British Journal of Nutrition Pub Date : 2026-05-07 DOI: 10.1017/S0007114526107399
Kewei Shi, Jean Woo, Kim L Schmidt, Eric Tc Lai, Jason Leung, Silvia E Stringhini, Michael S Kobor
{"title":"Differing Normative Reference Ranges for Body Composition and Physical Performance measures in Hong Kong Chinese and Canadian Older Adults: The Hong Kong Os Study and the Canadian Longitudinal Study on Aging.","authors":"Kewei Shi, Jean Woo, Kim L Schmidt, Eric Tc Lai, Jason Leung, Silvia E Stringhini, Michael S Kobor","doi":"10.1017/S0007114526107399","DOIUrl":"https://doi.org/10.1017/S0007114526107399","url":null,"abstract":"<p><p>Normal reference values for body composition and physical performance measures are needed in order to determine cut-off values for suboptimal health such as obesity and related cardiometabolic diseases, and/or sarcopenia. Few studies have provided comparative normative reference ranges across different populations. We compare several body composition and physical performance measures between older Hong Kong Chinese and Canadians to derive and contrast their respective reference values.17451 older adults from the Canadian Longitudinal Study on Aging (CLSA) and 4000 from the Hong Kong Mr. and Ms. Osteoporosis (Os) cohort aged 65 years and over were included to derive reference values for walking speed, grip strength, 5-times chair stand test (CST), percentage body fat (PBF), weight, body mass index (BMI), waist-hip ratio (WHR), and Conicity Index (C-index), stratified by age and sex.Overall normal reference values for Hong Kong males were higher compared with Canadians, particularly in younger age groups. The observations were reversed for females. Not surprisingly, Canadians have higher body weight and body mass index compared with Hong Kong older adults. Older Canadian males also have a higher percentage body fat and waist-hip ratio, compared with Hong Kong Older males. When fat distribution was compared, Hong Kong Chinese females have higher conicity index- indicating greater central fat distribution compared with Canadian females.Normative reference values are best derived in the context of ethnicity and geographic regions, when used in relation to health assessments requiring physical performance measures and body composition.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-27"},"PeriodicalIF":3.0,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association Between Dietary Inflammatory Index and Cardiometabolic Risk in Women with Polycystic Ovary Syndrome. 多囊卵巢综合征妇女饮食炎症指数与心脏代谢风险的关系
IF 3 3区 医学
British Journal of Nutrition Pub Date : 2026-05-06 DOI: 10.1017/S0007114526107405
Elif Ulug, Seren Aksun, Aylin Acikgoz Pinar, Bulent Okan Yildiz
{"title":"Association Between Dietary Inflammatory Index and Cardiometabolic Risk in Women with Polycystic Ovary Syndrome.","authors":"Elif Ulug, Seren Aksun, Aylin Acikgoz Pinar, Bulent Okan Yildiz","doi":"10.1017/S0007114526107405","DOIUrl":"https://doi.org/10.1017/S0007114526107405","url":null,"abstract":"<p><p>Polycystic ovary syndrome (PCOS) is associated with an increased risk of cardiometabolic disorders, often exacerbated by chronic inflammation. This study aims to investigate the effects of the Dietary Inflammatory Index (DII), a measure of the inflammatory potential of diet, on cardiometabolic risk factors in women with PCOS. We hypothesized positive associations between DII and adverse cardiometabolic profile in PCOS. In this case-control study, thirty-eight women with PCOS (mean age 21.6 years, BMI 26.3 kg/m<sup>2</sup>) and 39 age- and BMI-matched healthy controls (mean age 21.2 years, BMI 25.9 kg/m<sup>2</sup>) were included. Clinical, hormonal and biochemical assessments were conducted. Dietary intake was assessed using a validated food frequency questionnaire to calculate DII. Women with PCOS exhibited significantly higher fasting insulin, HOMA-IR, and a more adverse lipid profile compared to healthy controls, indicating increased cardiometabolic risk. These differences remained significant after adjusting for the DII, suggesting they are primarily attributable to PCOS, as shown by ANCOVA analysis. In contrast, higher TyG, CMI, and VAI values observed in the PCOS group were largely explained by DII. Furthermore, DII was positively associated with anthropometric and biochemical markers, including waist-to-hip ratio, fasting glucose, triglycerides, and cardiovascular risk indices, indicating that higher dietary inflammation is linked to poorer cardiometabolic health in women with PCOS. A pro-inflammatory dietary pattern, reflected by a higher DII score, is associated with unfavorable cardiometabolic risk factors in women with PCOS. These findings underscore the importance of dietary inflammation in the pathophysiology of PCOS and support anti-inflammatory dietary strategies to mitigate associated risks.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-21"},"PeriodicalIF":3.0,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147833873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Last Bite on the Plate, Association of Plate Clearing Tendency and Sustainable Nutrition with Weight Gain in Pregnancy. 最后一口在盘子上,盘子清理趋势和可持续营养与怀孕体重增加的关系。
IF 3 3区 医学
British Journal of Nutrition Pub Date : 2026-05-06 DOI: 10.1017/S0007114526107387
Ceren Şarahman-Kahraman, Cansu Memiç-İnan, Açelya Hür
{"title":"The Last Bite on the Plate, Association of Plate Clearing Tendency and Sustainable Nutrition with Weight Gain in Pregnancy.","authors":"Ceren Şarahman-Kahraman, Cansu Memiç-İnan, Açelya Hür","doi":"10.1017/S0007114526107387","DOIUrl":"https://doi.org/10.1017/S0007114526107387","url":null,"abstract":"<p><p>The aim is to examine the relationship between factors thought to potentially influence weight gain, such as sustainable nutrition (SN) behavior and plate clearing tendency (PCT) during pregnancy, and gestational weight gain (GWG). This cross-sectional correlational study was conducted on 340 women in the last trimester of pregnancy. Study data were collected through face-to-face interviews using a questionnaire form between October-December 2024. PCT is lower among younger women, those with low income and those with insufficient GWG (p<0.05). SN behaviors are higher in those who are older, have higher education levels, lower income and moderate physical activity (p<0.05). A negative correlation was found between food preference, a component of SN behaviors, and GWG (p<0.05). In the binary logistic regression model, higher pre-pregnancy BMI significantly increased the likelihood of excessive GWG (OR=1.49, 95% CI:1.332-1.665, p<0.001), whereas high physical activity was found to be protective against excessive GWG (OR=0.214, 95% CI:0.061-0.747, p=0.016). It was determined that pre-pregnancy BMI was higher and physical activity was lower in those with excessive GWG, in addition, food preference, one of the factors of SN behavior, affected weight gain. Food preference can be considered as a factor that may affect GWG.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-24"},"PeriodicalIF":3.0,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147833459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Supplementation with a cetoleic acid concentrate decreased the serum LDL-cholesterol concentration in healthy adults with overweight or obesity. A randomised double-blind controlled clinical trial. 补充鲸烯酸浓缩物可降低超重或肥胖的健康成人血清ldl -胆固醇浓度。一项随机双盲对照临床试验。
IF 3 3区 医学
British Journal of Nutrition Pub Date : 2026-05-06 DOI: 10.1017/S0007114526107375
Karine Hansen, Margrete Aske Mjaatveit, Linnea Vikane Andreassen, Svein Are Mjøs, Oddrun Anita Gudbrandsen
{"title":"Supplementation with a cetoleic acid concentrate decreased the serum LDL-cholesterol concentration in healthy adults with overweight or obesity. A randomised double-blind controlled clinical trial.","authors":"Karine Hansen, Margrete Aske Mjaatveit, Linnea Vikane Andreassen, Svein Are Mjøs, Oddrun Anita Gudbrandsen","doi":"10.1017/S0007114526107375","DOIUrl":"https://doi.org/10.1017/S0007114526107375","url":null,"abstract":"<p><p>Elevated LDL-cholesterol concentration is a major risk factor for CVD. Regular consumption of marine fish and seafood is associated with a reduced risk of CVD, although the n-3 PUFAs EPA and DHA have no cholesterol-lowering effect when given in physiologically relevant doses. Recent studies have demonstrated a lower LDL-cholesterol concentration in rodents after intake of cetoleic acid (CA, C22:1n-11), found in pelagic fish species such as herring. The primary aim was to investigate the effect of consuming capsules containing CA on LDL-cholesterol concentration in adults with overweight or obesity. The study was designed as a randomised clinical trial with two arms. Eighty participants were enrolled, and data from 75 participants were included in the statistical analyses. Participants consumed capsules containing either a CA concentrate (CECO group; 1480 mg CA and 232 mg EPA per day) or soyabean oil mixed with a n-3 PUFA concentrate without CA as comparator arm (SOYO3 group; 258 mg EPA/day) for eight weeks. The within-group changes in LDL-cholesterol were compared using ANCOVA with changes in body fat percentage as covariate. The LDL-cholesterol concentration was decreased from baseline to 8 weeks in the CECO group (<i>n</i> 37, median -0.1 (quartiles -0.1, 0.0) mmol/L) in comparison to the SOYO3 group (<i>n</i> 38, median 0.2 (quartiles 0.1, 0.2) mmol/L), with F=19.35, P=0.033 and η<sub>p</sub><sup>2</sup> = 0.212, corresponding to approximately 7% reduction in the CECO group relative to the SOYO3 group. To conclude, 8 weeks of dietary supplementation with CECO decreased the LDL-cholesterol concentration in adults with overweight or obesity.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-29"},"PeriodicalIF":3.0,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147833470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chrononutrition-based hypocaloric diets with varying macronutrient and protein distribution in shift workers with prediabetes or type 2 diabetes: Protocol for a randomized controlled trial. 以时间营养为基础的低热量饮食,改变糖尿病前期或2型糖尿病轮班工人的常量营养素和蛋白质分布:随机对照试验方案
IF 3 3区 医学
British Journal of Nutrition Pub Date : 2026-05-06 DOI: 10.1017/S0007114526107417
Carmen Rodrigo-Carbó, Mikel Tous-Espelosin, Irene Gracia-Rubio, Sofía Pérez-Calahorra, Ángela Lezcano-Enciso, Rebeca Monjón-González, Isabel Lamiquiz, Itziar Lamiquiz-Moneo, Rocío Mateo-Gallego
{"title":"Chrononutrition-based hypocaloric diets with varying macronutrient and protein distribution in shift workers with prediabetes or type 2 diabetes: Protocol for a randomized controlled trial.","authors":"Carmen Rodrigo-Carbó, Mikel Tous-Espelosin, Irene Gracia-Rubio, Sofía Pérez-Calahorra, Ángela Lezcano-Enciso, Rebeca Monjón-González, Isabel Lamiquiz, Itziar Lamiquiz-Moneo, Rocío Mateo-Gallego","doi":"10.1017/S0007114526107417","DOIUrl":"https://doi.org/10.1017/S0007114526107417","url":null,"abstract":"<p><p>Shift work is associated with an increased risk of metabolic disorders, including type 2 diabetes, largely due to circadian misalignment, irregular meal patterns, and suboptimal diet quality. Chrononutrition, which focuses on aligning nutrient intake with circadian rhythms, has emerged as a promising strategy to improve metabolic health. Protein intake plays a key role in glucose homeostasis, and high-protein hypocaloric diets have shown benefits in people with type 2 diabetes. However, the effects of higher evening protein intake in shift workers remain unclear. This trial aims to analyze the effect of three hypocaloric diets differing in macronutrient composition and distribution throughout the day on glycemic control, body composition, and other secondary outcomes in shift workers with overweight or obesity and prediabetes or type 2 diabetes. This is a 12-week, three-arm, parallel-group, single-blind randomized controlled trial including 126 shift workers. Participants are randomized equally to: (A) a high-protein diet with protein-enriched dinner (50-60% of daily protein); (B) a high-protein diet with protein-restricted dinner (10-20% of daily protein); or (C) a normoproteic control diet with usual protein distribution. Primary outcomes include changes in glycemic control and DXA-derived body composition. Secondary outcomes are lipid profile, sleep quality, and quality of life. Other clinical and lifestyle parameters are evaluated to monitor changes throughout the intervention. Assessments are performed at baseline, week 6, and week 12. All analyses will follow the intention-to-treat principle. This study will provide new evidence on how evening protein intake may influence metabolic health in populations exposed to circadian disruption.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-28"},"PeriodicalIF":3.0,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147833948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Omega-6 polyunsaturated fatty acids and adiposity in the UK Biobank Cohort: a cross-sectional and longitudinal prospective analysis. -6多不饱和脂肪酸和肥胖在英国生物库队列:横断面和纵向前瞻性分析。
IF 3 3区 医学
British Journal of Nutrition Pub Date : 2026-05-06 DOI: 10.1017/S0007114526107430
Heidi Tm Lai, Jason Westra, Evan De Jong, Nathan L Tintle, Martha A Belury, William S Harris
{"title":"Omega-6 polyunsaturated fatty acids and adiposity in the UK Biobank Cohort: a cross-sectional and longitudinal prospective analysis.","authors":"Heidi Tm Lai, Jason Westra, Evan De Jong, Nathan L Tintle, Martha A Belury, William S Harris","doi":"10.1017/S0007114526107430","DOIUrl":"https://doi.org/10.1017/S0007114526107430","url":null,"abstract":"<p><p>The role of omega-6 polyunsaturated fatty acids (PUFAs), especially linoleic acid (LA) in adiposity, remains contested. While clinical interventions suggest improved body composition with higher LA intake, observational evidence using dietary data is inconsistent, and few studies consider circulating fatty acids or longitudinal changes in adiposity. Using multivariable linear models, we evaluated cross-sectional and longitudinal associations between omega-6 PUFAs and waist circumference (WC), weight, and whole-body fat mass (FM) in the UK Biobank Cohort. Cross-sectionally (N=272,587, 54% female, mean age 57 years), higher circulating LA was inversely associated with WC, weight, and FM. Participants in the highest versus lowest quintile of LA had significantly smaller WC [-11.04 (-11.17, -10.91) cm], lower weight [-11.77 (-11.92, -11.62) kg], and lower FM [-7.87 (-7.97, -7.77) kg]. Associations for total omega-6 were generally consistent with those for LA. Conversely, non-LA omega-6 was positively associated with WC [1.46 (1.32, 1.61) cm], weight [2.41 (2.25, 2.58) kg], and FM [1.81 (1.69, 1.92) kg]. Longitudinal analyses (N=58,335, 51% female, mean age 55 years) largely corroborate these patterns, with annual changes in WC, weight, and FM inversely associated with LA and positively associated with non-LA omega-6. Higher circulating LA, but not non-LA omega-6, was associated with lower WC, weight, and FM both cross-sectionally and longitudinally. Our findings potentially support dietary recommendations to promote LA-rich oils. Divergent associations between LA and non-LA omega-6 caution against treating omega-6 PUFAs as a homogenous group. Examining distinct health effects of individual non-LA omega-6 are warranted.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-23"},"PeriodicalIF":3.0,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maternal First Trimester SIMPLE Nutritional Score and Intrauterine Fetal Growth Trajectory: A Prospective Multicenter Italian study (SIMPLE study). 母亲妊娠早期SIMPLE营养评分和宫内胎儿生长轨迹:一项意大利前瞻性多中心研究(SIMPLE研究)。
IF 3 3区 医学
British Journal of Nutrition Pub Date : 2026-05-06 DOI: 10.1017/S0007114526107144
F Parisi, G Esposito, G M Anelli, C Lubrano, V M Savasi, A Spinillo, G Capobianco, M Bosco, F Petraglia, A Ciavattini, A Lanzone, P Greco, F E Odicino, N Colacurci, G Bifulco, M Vignali, M Palumbo, I Cetin
{"title":"Maternal First Trimester SIMPLE Nutritional Score and Intrauterine Fetal Growth Trajectory: A Prospective Multicenter Italian study (SIMPLE study).","authors":"F Parisi, G Esposito, G M Anelli, C Lubrano, V M Savasi, A Spinillo, G Capobianco, M Bosco, F Petraglia, A Ciavattini, A Lanzone, P Greco, F E Odicino, N Colacurci, G Bifulco, M Vignali, M Palumbo, I Cetin","doi":"10.1017/S0007114526107144","DOIUrl":"https://doi.org/10.1017/S0007114526107144","url":null,"abstract":"<p><p>This longitudinal, prospective, multicenter observational cohort study investigates the associations between maternal nutritional status-assessed using the first trimester SIMPLE score and pregestational BMI-and fetal growth trajectories and velocity, as proxies for intrauterine development. Healthy women with singleton pregnancies undergoing first trimester screening were enrolled. Adherence to a healthy lifestyle was evaluated using the SIMPLE score, categorizing participants into low (<6) and high (≥6) adherence groups. Fetal growth parameters - including biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC), femur length (FL), estimated fetal weight (EFW)- were assessed during second and third trimester ultrasounds, and birth outcomes were recorded. Multi-adjusted linear mixed models examined associations between SIMPLE score groups, individual score items, pregestational BMI, and fetal growth, with analyses stratified by fetal sex. Out of 938 enrolled women, 109 (11.6%) were classified as the low adherence group. Multi-adjusted linear mixed models showed that low adherence was associated with decreased EFW acceleration from the second to the third trimester. Stratification by fetal sex confirmed the association only among male fetuses. Analysis of pregestational BMI and individual SIMPLE score items revealed significant positive associations between pregestational BMI, AC, and EFW growth velocity, and a negative association between first trimester hemoglobin [>110 g/l] and EFW growth velocity. Overall, these findings confirm the clinical utility of the SIMPLE score, demonstrating significant associations with intrauterine growth trajectories and velocity, independent of other markers of nutritional status (e.g., pregestational BMI).</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-28"},"PeriodicalIF":3.0,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Overweight and Obesity Among Vietnamese University Students: Prevalence and Associated Factors. 越南大学生超重和肥胖:患病率和相关因素。
IF 3 3区 医学
British Journal of Nutrition Pub Date : 2026-05-05 DOI: 10.1017/S000711452610734X
Thi Phuong Duong, Thi Huong Le, Thi Thanh Xuan Le, Nam Khanh Do, Thi Quan Pham, Thi Huong Giang Nguyen, Hong Ngoc Bui, Thi Thu Lieu Nguyen, Duc Huy Do, Minh Giang Le
{"title":"Overweight and Obesity Among Vietnamese University Students: Prevalence and Associated Factors.","authors":"Thi Phuong Duong, Thi Huong Le, Thi Thanh Xuan Le, Nam Khanh Do, Thi Quan Pham, Thi Huong Giang Nguyen, Hong Ngoc Bui, Thi Thu Lieu Nguyen, Duc Huy Do, Minh Giang Le","doi":"10.1017/S000711452610734X","DOIUrl":"https://doi.org/10.1017/S000711452610734X","url":null,"abstract":"<p><strong>Background: </strong>Overweight and obesity are emerging public health challenges among young adults in Vietnam, particularly within university settings where lifestyle transitions frequently occur.</p><p><strong>Objectives: </strong>To determine the prevalence of overweight and obesity among university students in Vietnam and identify associated sociodemographic and behavioral factors.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among 2,000 students from ten universities across Northern, Central, and Southern Vietnam. Anthropometric measurements were collected using standardized procedures. Overweight and obesity were diagnosed according to the World Health Organization recommendations for Asian populations, with a cut-off of BMI ≥ 23 kg/m<sup>2</sup>. Multivariable logistic regression was performed to examine factors independently associated with overweight and obesity.</p><p><strong>Results: </strong>Among 2,000 students, 25.5% were overweight or obese (12.3% overweight, 13.2% obese), with prevalence significantly higher in males than females (35.1% vs. 17.5%, p < 0.001). Regional differences were observed, with underweight more common in Central Vietnam and overweight and obesity most prevalent in the South, p < 0.05. Multivariable analysis showed significant associations between overweight or obesity and male sex (OR = 2.8), ethnic minority status (OR = 1.7), Southern residence (OR = 1.9), high waist to hip ratio (OR = 4.2), and being married (OR = 3.2). Prolonged weight loss dieting was positively associated (OR = 2.9), while sleeping 8 to 10 hours per day was associated with lower odds (OR = 0.6).</p><p><strong>Conclusion: </strong>Overweight and obesity affect approximately one in four university students in Vietnam. Targeted prevention and long-term weight management strategies are needed for young adults in academic settings.</p>","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-24"},"PeriodicalIF":3.0,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147833514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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