British Journal of Nutrition最新文献_第2页

Plant and animal protein intakes are differentially associated with diet quality and obesity: Findings from the Australian National Nutrition and Physical Activity Survey of Australian adults.

IF 3 3区医学

British Journal of Nutrition Pub Date : 2025-03-27 DOI: 10.1017/S0007114525000674

Hesti Retno Budi Arini, Rebecca M Leech, Sze-Yen Tan, Sarah A McNaughton

{"title":"Plant and animal protein intakes are differentially associated with diet quality and obesity: Findings from the Australian National Nutrition and Physical Activity Survey of Australian adults.","authors":"Hesti Retno Budi Arini, Rebecca M Leech, Sze-Yen Tan, Sarah A McNaughton","doi":"10.1017/S0007114525000674","DOIUrl":"https://doi.org/10.1017/S0007114525000674","url":null,"abstract":"Dietary guidelines often combine plant and animal protein intake recommendations, yet some evidence suggests they may have distinct associations with diet quality and obesity. This study aimed to examine relationships between animal and plant protein intake, based on different protein classification approaches, and diet quality and obesity. Plant and animal protein contents of foods reported by 7637 adult participants aged ≥19 years during the 2011-12 Australian National Nutrition and Physical Activity Survey were estimated using Australian food composition databases. Usual animal, plant, and total protein intakes were estimated using Multiple Source Method. Diet quality was assessed using the 2013-Dietary Guidelines Index (DGI), and obesity measures included BMI and waist circumference (WC). Sex-stratified multiple linear and logistic regressions were performed and adjusted for potential confounders. Plant and animal protein intakes were positively associated with DGI scores [Plant protein: men, β=0.74(95%CI: 0.64, 0.85); women, β=0.78(0.67, 0.89); Animal protein: men, β=0.15(0.12, 0.18); women, β=0.26(0.22, 0.29)]. These associations were consistent when examining high-quality plant protein (i.e., high-protein-containing plant-based foods with comparable nutritional values to animal proteins) and non-dairy animal protein intakes. Plant protein intake was inversely associated with BMI and WC in men but not women. Animal protein intake was positively associated with BMI in men and women and WC in men only [β=0.04(0.02, 0.07)]. Plant protein intake was inversely associated with obesity [OR=0.97(0.96, 0.99)] and central obesity [OR=0.97(0.95, 0.98)] among men only. Further studies are needed to examine the influence of different animal protein sources by accounting for energy intake and sex-specific associations.","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-29"},"PeriodicalIF":3.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of the sulfur microbial diet and biological aging: a cross-sectional study of 71,579 participants.

IF 3 3区医学

British Journal of Nutrition Pub Date : 2025-03-27 DOI: 10.1017/S0007114525000534

Ye Liu, Dan He, Yifan Gou, Ruixue Zhou, Chen Liu, Jingni Hui, Meijuan Kang, Bingyi Wang, Panxing Shi, Feng Zhang

{"title":"Association of the sulfur microbial diet and biological aging: a cross-sectional study of 71,579 participants.","authors":"Ye Liu, Dan He, Yifan Gou, Ruixue Zhou, Chen Liu, Jingni Hui, Meijuan Kang, Bingyi Wang, Panxing Shi, Feng Zhang","doi":"10.1017/S0007114525000534","DOIUrl":"https://doi.org/10.1017/S0007114525000534","url":null,"abstract":"The sulfur microbial diet (SMD), a dietary pattern associated with 43 sulfur-metabolizing bacteria, may influence gut microbiota composition and contribute to aging process through gut-produced hydrogen sulfide (H2S). We aimed to explore the association between SMD and biological age acceleration, using the cross-sectional study included 71,579 individuals from the UK Biobank. The SMD score was calculated by multiplying β-coefficients by corresponding serving sizes and summing them, based on dietary data collected using the Oxford WebQ, a 24-hour dietary assessment tool. Biological age (BA) was assessed using Klemerae-Doubal (KDM) and PhenoAge methods. The difference between BA and chronological age refers to the age acceleration (AgeAccel), termed \"KDMAccel\" and \"PhenoAgeAccel\". Generalized linear regression was performed. Mediation analyses were used to investigate underlying mediators including body mass index (BMI) and serum aspartate aminotransferase/alanine aminotransferase (AST/ALT) ratio. Following adjustment for multiple variables, a positive association was observed between consuming a dietary pattern with a higher SMD score and both KDMAccel (βQ4vsQ1 = 0.35, 95%CI = 0.27 to 0.44, P<0.001) and PhenoAgeAccel (βQ4vsQ1 = 0.32, 95%CI = 0.23 to 0.41, P<0.001). Each 1-standard deviation increase in SMD score was positively associated with the acceleration of biological age by 7.90% for KDMAccel (P<0.001) and 7.80% for PhenoAgeAccel (P<0.001). BMI and AST/ALT mediated the association. The stratified analysis revealed stronger accelerated aging impacts in males and smokers. Our study indicated a higher SMD score is associated with elevated markers of biological aging, supporting the potential utility of gut microbiota-targeted dietary interventions in attenuating the aging process.","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-23"},"PeriodicalIF":3.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adherence to the Healthy Eating Guidelines in the MyPlanetDiet study is associated with healthier and more sustainable diets.

IF 3 3区医学

British Journal of Nutrition Pub Date : 2025-03-26 DOI: 10.1017/S0007114525000662

Katie P Davies, Eileen R Gibney, Ursula M Leonard, Leona Lindberg, Jayne V Woodside, Mairead E Kiely, Anne P Nugent, Elena Arranz, Marie C Conway, Sinead N McCarthy, Aifric M O'Sullivan

{"title":"Adherence to the Healthy Eating Guidelines in the MyPlanetDiet study is associated with healthier and more sustainable diets.","authors":"Katie P Davies, Eileen R Gibney, Ursula M Leonard, Leona Lindberg, Jayne V Woodside, Mairead E Kiely, Anne P Nugent, Elena Arranz, Marie C Conway, Sinead N McCarthy, Aifric M O'Sullivan","doi":"10.1017/S0007114525000662","DOIUrl":"https://doi.org/10.1017/S0007114525000662","url":null,"abstract":"Environmental impacts of food systems have stimulated research to examine how to create healthy diets that will be more sustainable while meeting nutrient requirements. Increasing compliance with existing food-based dietary guidelines in most jurisdictions could be a first step to improve health and reduce environmental impact. MyPlanetDiet was an all-Ireland 12-week randomised controlled trial designed to inform sustainable healthy dietary guidelines. Healthy adults (n=355) aged 18-64 years with moderate-to-high greenhouse gas emitting (GHGE) diets were recruited from three study sites on the island of Ireland. The aim of this research is to assess the relationship between dietary intakes, diet-related environmental impacts, and metabolic health using baseline data collected during the MyPlanetDiet study. Dietary assessments collected using Foodbook24 were used to calculate diet-related GHGE, adherence to Healthy Eating Guidelines (HEG), and Healthy Eating Index (HEI) score. Anthropometrics and metabolic health markers (e.g. lipids, glucose and insulin) were included. Overall HEG adherence was low, with 43% meeting zero or one HEG food group recommendations. Adherence to 4+ HEG food group targets was associated with 31% lower diet-related GHGE compared to those with lowest adherence. Higher HEG adherence was associated with lower BMI and waist circumference and higher HEI scores. While our findings suggest HEG adherence is associated with positive health and environmental impacts, substantial behaviour change will be needed to meet existing HEGs. Further research is needed to assess response and acceptability to HEG. However, adherence to HEG may be an important first step to reducing the environmental impact of food consumption.","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-26"},"PeriodicalIF":3.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Energy accuracy of nutritional fluids provided in hospital: Comparing nutrition label values against direct bomb calorimetry.

IF 3 3区医学

British Journal of Nutrition Pub Date : 2025-03-24 DOI: 10.1017/S0007114525000601

Zane Hopper, Christopher Irwin, Shelley Roberts, Ben Desbrow

{"title":"Energy accuracy of nutritional fluids provided in hospital: Comparing nutrition label values against direct bomb calorimetry.","authors":"Zane Hopper, Christopher Irwin, Shelley Roberts, Ben Desbrow","doi":"10.1017/S0007114525000601","DOIUrl":"https://doi.org/10.1017/S0007114525000601","url":null,"abstract":"Mandatory thresholds for accuracy of reported energy on food and beverage product labels do not exist for many countries. Accurate nutrition information is essential for ensuring nutritional adequacy among hospital patients. The aim of this study was to compare direct measures of energy of nutritional fluids provided in hospital to values determined via manufacturers' specifications. Nutritional fluids were identified as any liquid provided to hospital patients orally, enterally, or parenterally, to deliver nutrition. These were categorised into six groups aligned to food/medical standards, including: 1) local recipes, 2) pre-packaged general fluids, 3) supplementary fluids, 4) prescribed nutrition fluids - thickened, 5) prescribed nutrition fluids - oral/enteral, and 6) prescribed medical nutrition - IV and parenteral. An equivalence testing statistical approach (±10% thresholds) was used to compare energy values derived directly via bomb calorimetry against those obtained from manufacturer specifications. A total of 69 fluids were measured. One fifth (n=14) exhibited non-equivalent energy values, with majority of these (n=11; 79%) likely to contain fewer calories than that calculated from reported values. Almost all (34/35; 97%) prescribed nutrition fluids (oral/enteral (20/20; 100%), IV and parenteral (7/7; 100%) and thickened fluid (7/8; 88%) products were equivalent. In contrast, only 21/34 (62%) non-prescribed fluids (local recipes (2/11; 18%), supplementary fluids (4/5; 80%) and pre-packaged general fluid (15/18; 83%) products) demonstrated equivalence. Energy content of nutritional fluids prescribed to hospital patients typically align with manufacturers' values. Consumption of non-prescribed fluids may result in lower energy intakes than expected.","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-24"},"PeriodicalIF":3.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serum 25-hydroxyvitamin D mediates the association of triglyceride-glucose index with hypertension in US adults from NHANES 2001-2018: a national cross-sectional study.

IF 3 3区医学

British Journal of Nutrition Pub Date : 2025-03-24 DOI: 10.1017/S0007114525000571

Jing Lu, Mengying Cao, Xiaoxue Zhang, Wenhao Zhong, Jie Yuan, Yunzeng Zou

{"title":"Serum 25-hydroxyvitamin D mediates the association of triglyceride-glucose index with hypertension in US adults from NHANES 2001-2018: a national cross-sectional study.","authors":"Jing Lu, Mengying Cao, Xiaoxue Zhang, Wenhao Zhong, Jie Yuan, Yunzeng Zou","doi":"10.1017/S0007114525000571","DOIUrl":"https://doi.org/10.1017/S0007114525000571","url":null,"abstract":"This study was designed to explore the mediating role of serum 25-hydroxyvitamin D (25(OH) D) in triglyceride glucose (TyG) index and hypertension (HTN). Study participants were selected from the 2001-2018 National Health and Nutrition Examination Survey. Firstly, we estimated the association between TyG index, and serum 25(OH)D with HTN using weighted multivariable logistic regression model and restricted cubic spline. Secondly, we used generalized additive model to investigate the correlation between TyG index and serum 25(OH)D. Lastly, serum 25(OH)D was investigated as a mediator in the association between TyG index and HTN. There were 14,099 subjects in total. TyG index was positively and linearly associated with HTN risk, while serum 25(OH)D had a U-shaped relationship with prevalence of HTN. When the serum 25(OH)D levels were lower than 57.464 mmol/L, prevalence of HTN decreased with the increase of serum 25(OH)D levels. When serum 25(OH)D levels rise above 57.464 mmol/L, risk of HTN increased rapidly. Based on the U-shaped curve, serum 25(OH)D concentrations were divided into two groups: (<57.464 and ≥57.464 mmol/L). According to the mediation analysis, when serum 25(OH)D levels <57.464 mmol/L, the positive association between TyG index and incident HTN was increased by 25(OH)D. When serum 25(OH)D levels ≥57.464 mmol/L, the negative association between TyG index and incident HTN was increased by 25(OH)D. There was a mediation effect between TyG index and HTN, which was mediated by 25(OH)D. Therefore, we found that the association between serum 25(OH)D levels and TyG index may influence prevalence of HTN.","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-32"},"PeriodicalIF":3.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of fat-emulsion-based early parenteral nutrition for patients after hemihepatectomy.

IF 3 3区医学

British Journal of Nutrition Pub Date : 2025-03-24 DOI: 10.1017/S0007114525000613

Leyi Liao, Yang Lei, Qinghua He, Hanbiao Liang, Jie Zhou, Kai Wang, Chuanjiang Li

{"title":"Effects of fat-emulsion-based early parenteral nutrition for patients after hemihepatectomy.","authors":"Leyi Liao, Yang Lei, Qinghua He, Hanbiao Liang, Jie Zhou, Kai Wang, Chuanjiang Li","doi":"10.1017/S0007114525000613","DOIUrl":"https://doi.org/10.1017/S0007114525000613","url":null,"abstract":"This study investigates the effects of fat-emulsion-based early parenteral nutrition in patients following hemihepatectomy, addressing a critical gap in clinical knowledge regarding parenteral nutrition after hemihepatectomy. We retrospectively analyzed clinical data from 274 patients received non-fat-emulsion-based parenteral nutrition (non-fatty nutrition group) and 297 patients received fat-emulsion-based parenteral nutrition (fatty nutrition group) after hemihepatectomy. Fat-emulsion-based early parenteral nutrition significantly reduced levels of postoperative aspartate aminotransferase, total bilirubin, and direct bilirubin, while minor decreases in red blood cell and platelet counts were observed in the fatty nutrition group. Importantly, fat-emulsion-based early parenteral nutrition shortened lengths of postoperative hospital stay and fasting duration, but did not affect the incidence of short-term postoperative complications. Subgroup analyses revealed that the supplement of omega-3 fish oil emulsions was significantly associated with a reduced inflammatory response and risk of postoperative infections. These findings indicate that fat-emulsion-based early parenteral nutrition enhances short-term postoperative recovery in patients undergoing hemihepatectomy.","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-23"},"PeriodicalIF":3.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dietary chenodeoxycholic acid inclusion improves carbohydrate utilization and inflammation of largemouth bass (Micropterus salmoides) partly mediated by the activation of farnesoid X receptor.

IF 3 3区医学

British Journal of Nutrition Pub Date : 2025-03-24 DOI: 10.1017/S0007114525000583

Wenfei Li, Nihe Zhang, Ning Liu, Shiwen Chen, Ye Gong, Naisong Chen, Songlin Li

{"title":"Dietary chenodeoxycholic acid inclusion improves carbohydrate utilization and inflammation of largemouth bass (Micropterus salmoides) partly mediated by the activation of farnesoid X receptor.","authors":"Wenfei Li, Nihe Zhang, Ning Liu, Shiwen Chen, Ye Gong, Naisong Chen, Songlin Li","doi":"10.1017/S0007114525000583","DOIUrl":"https://doi.org/10.1017/S0007114525000583","url":null,"abstract":"This study evaluated the effects of chenodeoxycholic acid (CDCA), a farnesoid X receptor (FXR) potential activator, on growth performance, antioxidant capacity, glucose metabolism, and inflammation in largemouth bass (Micropterus salmoides) (initial body weight: 5.45 ± 0.02 g) fed a high-carbohydrate diet. Experimental diets included a positive control (5 % α-starch), a negative control (10 % α-starch), and two diets containing 10 % α-starch supplemented with either 0.05 % or 0.10 % CDCA. After 8 weeks, the high-carbohydrate diet reduced growth performance and increased hepatosomatic and viscerosomatic indexes, which were mitigated by 0.10 % CDCA supplementation. The high-carbohydrate diet also increased hepatic glycogen and crude lipid content, both of which were reduced by 0.10 % CDCA. Furthermore, the high-carbohydrate diet induced oxidative stress, histopathological changes, and reduced liver lysozyme activity, which were ameliorated by CDCA supplementation. Molecular analysis showed that the high-carbohydrate diet suppressed FXR and phosphorylated AKT1 (p-AKT1) protein expression in the liver, downregulated insulin signaling (ira, irs, pi3kr1 and akt1), gluconeogenesis (pepck and g6pc), and glycolysis genes (gk, pk and pfkl). CDCA supplementation upregulated fxr expression, activated shp, enhanced the expression of insulin signaling and glycolytic genes (gk, pk and pfkl), and inhibited gluconeogenesis. Additionally, CDCA reduced inflammatory markers (nf-κb and il-1β) and restored anti-inflammatory mediators (il-10, iκb, and tgf-β). In conclusion, 0.10 % CDCA improved carbohydrate metabolism and alleviated liver inflammation in largemouth bass fed a high dietary carbohydrate, partially through FXR activation.","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-33"},"PeriodicalIF":3.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PATHOPHYSIOLOGICAL AND NUTRITIONAL ASPECTS IN THE ETIOLOGY AND MANAGEMENT OF GASTROESOPHAGEAL REFLUX DISEASE.

IF 3 3区医学

British Journal of Nutrition Pub Date : 2025-03-24 DOI: 10.1017/S0007114525000649

Daniel Ferreira da Silva, Rayana Líbia Vieira Lima, Pedro Carrera-Bastos, Damien Ribeiro Maia, Paulo Marconi Linhares Mendonça

引用次数: 0

High dose fish oil supplements are more effective than oily fish in altering the number and function of extracellular vesicles in healthy human subjects: A randomized, double-blind, placebo-controlled, parallel trial. 在改变健康人细胞外囊泡的数量和功能方面，高剂量鱼油补充剂比油性鱼类更有效：随机、双盲、安慰剂对照、平行试验。

IF 3 3区医学

British Journal of Nutrition Pub Date : 2025-03-21 DOI: 10.1017/S0007114525000625

Amal Sharman, Ruihan Zhou, Jamie Pugh, Graeme Close, Helena L Fisk, Philip C Calder, Parveen Yaqoob

{"title":"High dose fish oil supplements are more effective than oily fish in altering the number and function of extracellular vesicles in healthy human subjects: A randomized, double-blind, placebo-controlled, parallel trial.","authors":"Amal Sharman, Ruihan Zhou, Jamie Pugh, Graeme Close, Helena L Fisk, Philip C Calder, Parveen Yaqoob","doi":"10.1017/S0007114525000625","DOIUrl":"https://doi.org/10.1017/S0007114525000625","url":null,"abstract":"N-3 polyunsaturated fatty acids (n-3 PUFAs) delivered by fish oil supplements alter the number and functions of circulating extracellular vesicles (EVs), but consumption of oily fish does not reproduce this effect. In order to assess the effects of fish oil supplements and oily fish, at a level achievable in the diet, on EV numbers, composition and procoagulant activity in healthy human volunteers, forty-two healthy subjects were assigned to one of three treatment groups: (i) fish oil supplements plus white fish meals, (ii) control supplements plus oily fish meals or (iii) control supplements plus white fish meals for 12 weeks in a randomized, double-blind, placebo-controlled, parallel trial; circulating EVs were enumerated and their procoagulant activity assessed using thrombin generation and fibrinolysis assays. Our results showed that fish oil supplements decreased circulating EV numbers and reduced EV-stimulated thrombin generation, but the consumption of oily fish at half the dose of EPA had no effect on either EV number or thrombogenic capacity. Consumption of both oily fish and fish oil supplements increased the EPA and DHA contents of EVs and the proportion of EPA in circulating EVs was strongly associated with EV-stimulated thrombin generation. This study revealed that the additional 1 g/d EPA delivered in the fish oil supplements is required to decrease the numbers and thrombogenic capacity of EVs, since oily fish at a level achievable in the diet had no effect. Increasing EPA intake beyond current guidelines for oily fish consumption may therefore be required for cardiovascular benefits relating to EVs.","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-32"},"PeriodicalIF":3.0,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Consumption of artificial sweeteners during pregnancy and the risk of overweight in the offspring. 孕期食用人造甜味剂与后代超重的风险

IF 3 3区医学

British Journal of Nutrition Pub Date : 2025-03-21 DOI: 10.1017/S0007114525000455

Eva M Gjørup, Bodil H Bech, Sofie Stampe, Thorhallur I Halldorsson, Anne A Bjerregaard, Sjurdur F Olsen, Per G Ovesen, Magnus Leth-Møller

{"title":"Consumption of artificial sweeteners during pregnancy and the risk of overweight in the offspring.","authors":"Eva M Gjørup, Bodil H Bech, Sofie Stampe, Thorhallur I Halldorsson, Anne A Bjerregaard, Sjurdur F Olsen, Per G Ovesen, Magnus Leth-Møller","doi":"10.1017/S0007114525000455","DOIUrl":"10.1017/S0007114525000455","url":null,"abstract":"Artificial sweeteners are used to reduce energy intake, but studies suggest that consumption during pregnancy may impact the offspring's risk of overweight. In this longitudinal cohort study, we aimed to examine the association between consumption of artificially sweetened or sugar-sweetened beverages during pregnancy and offspring overweight from birth to 18 years in the Danish National Birth Cohort. A total of 101 042 pregnancies were enrolled in the Danish National Birth Cohort from 1996 to 2002. Follow-up was conducted throughout pregnancy, childhood and adolescence. Additionally, 72 821 women completed an FFQ during pregnancy, reporting intake of beverages sweetened with artificial sweeteners or sugar. Offspring height and weight were obtained during childhood and adolescence. Multivariate logistic regression was performed to estimate the OR for overweight concerning maternal beverage consumption. Analyses were adjusted for risk factors for childhood overweight, including maternal age, pre-pregnancy BMI, physical activity and smoking in pregnancy, healthy eating index, paternal BMI, socio-economic status and duration of breastfeeding. We found increased odds of overweight in 7-, 11-, 14- and 18-year-old offspring whose mothers reported drinking ≥ 1 artificially sweetened beverage daily during pregnancy compared with no consumption (18 years: adjusted OR 1·26 (95 % CI 1·12, 1·42)). We found decreased adjusted odds of overweight in 11- and 18-year-old offspring whose mothers reported drinking ≥ 1 sugar-sweetened beverage daily during pregnancy compared with no consumption. We found that consumption of artificially sweetened beverages during pregnancy was associated with an increased risk of overweight in childhood and adolescence after adjustment for risk factors for childhood overweight.","PeriodicalId":9257,"journal":{"name":"British Journal of Nutrition","volume":" ","pages":"1-11"},"PeriodicalIF":3.0,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0