Brain Stimulation最新文献

{"title":"SPARK-DBS: Toward standardized analysis of deep brain stimulation data","authors":"Savir Madan , Patricia Zvarova , Konstantin Butenko , Till A. Dembek , Bahne H. Bahners , Lukas L. Goede , Garance M. Meyer , Lauren A. Hart , Julianna Pijar , Clemens Neudorfer , Nanditha Rajamani , Ningfei Li , Michael T. Hayes , G. Rees Cosgrove , Calvin W. Howard , Michael D. Fox , Andreas Horn","doi":"10.1016/j.brs.2026.103114","DOIUrl":"10.1016/j.brs.2026.103114","url":null,"abstract":"","PeriodicalId":9206,"journal":{"name":"Brain Stimulation","volume":"19 3","pages":"Article 103114"},"PeriodicalIF":8.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147873503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From nerve to brain: External trigeminal stimulation as a novel neuroprotective strategy for acute ischemic stroke","authors":"Rui Zhao , Chen Cheng , Xingyu Liu , Jiale Li , Rui Zhao , Jiaxin Ye , Xiao Zeng , Jin-Bo Sun , Peng Liu , Hui Qiao , Xue-Juan Yang","doi":"10.1016/j.brs.2026.103112","DOIUrl":"10.1016/j.brs.2026.103112","url":null,"abstract":"","PeriodicalId":9206,"journal":{"name":"Brain Stimulation","volume":"19 3","pages":"Article 103112"},"PeriodicalIF":8.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147762944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thermal bioeffects considerations for transcranial focused ultrasound associated neurodegeneration","authors":"Alon Gilad , Shy Shoham","doi":"10.1016/j.brs.2026.103102","DOIUrl":"10.1016/j.brs.2026.103102","url":null,"abstract":"","PeriodicalId":9206,"journal":{"name":"Brain Stimulation","volume":"19 3","pages":"Article 103102"},"PeriodicalIF":8.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147762927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dithering suppresses half-harmonic neural synchronisation to photic stimulation in humans","authors":"Benoit Duchet ,&nbsp;Samini Subramaniam ,&nbsp;Alexander Greenway ,&nbsp;Shenghong He ,&nbsp;Nicholas Shackle ,&nbsp;Alek Pogosyan ,&nbsp;Timothy Denison ,&nbsp;Andrew Sharott ,&nbsp;Huiling Tan ,&nbsp;Rafal Bogacz","doi":"10.1016/j.brs.2026.103111","DOIUrl":"10.1016/j.brs.2026.103111","url":null,"abstract":"<div><h3>Background:</h3><div>While entraining neural rhythms using brain stimulation has been suggested as a therapeutic mechanism to normalise brain activity in conditions such as depression, chronic pain, or Alzheimer’s disease, periodic stimulation can also inadvertently entrain brain rhythms at sub- and superharmonics of the stimulation frequency, which could lead to deleterious effects. Slightly jittering stimulation pulses (called “dithering”) was previously proposed on the basis of mathematical modelling to selectively entrain a target neural rhythm while avoiding harmonic entrainment. In this study, we investigated the potential of dithering in humans.</div></div><div><h3>Methods:</h3><div>We recorded EEG in healthy adults during photic stimulation (light flicker) under periodic, dithered, reduced-strength, and control conditions. Synchronisation was quantified using spectral power and the phase-locking value.</div></div><div><h3>Results:</h3><div>We showed that dithering suppresses half-harmonic synchronisation relative to perfectly periodic flicker, and that dithering affects synchronisation at the stimulation frequency less than at the half-harmonic. This was also the case for a periodic condition with reduced stimulation strength, as predicted by theory. Furthermore, we demonstrated using synthetic data and modelling that the half-harmonic responses observed in participants cannot be explained by the superposition of evoked responses (even when modulated at the half-harmonic frequency), and are better matched by a minimal oscillator model.</div></div><div><h3>Conclusion:</h3><div>Our findings are consistent with half-harmonic EEG synchronisation in response to photic stimulation predominantly reflecting half-harmonic entrainment rather than the summation of evoked responses, and with dithering being an effective strategy to suppress subharmonic entrainment without reducing the energy delivered.</div></div>","PeriodicalId":9206,"journal":{"name":"Brain Stimulation","volume":"19 3","pages":"Article 103111"},"PeriodicalIF":8.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147762862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circuit-informed targeting for psychiatric comorbidity in depression: An accelerated TMS pilot study","authors":"Lauren L. Sanderson ,&nbsp;Anjali Chandra ,&nbsp;Emma Jones ,&nbsp;Leanna Bomer ,&nbsp;Natalie Hall ,&nbsp;Marina R. Kare ,&nbsp;David Lawson ,&nbsp;Nicole Chiulli ,&nbsp;Ryan D. Webler ,&nbsp;Sheena R. Baratono ,&nbsp;Irene Gonsalvez ,&nbsp;Stanley Lyndon ,&nbsp;Michael D. Fox ,&nbsp;Shan H. Siddiqi ,&nbsp;Joseph J. Taylor","doi":"10.1016/j.brs.2026.103106","DOIUrl":"10.1016/j.brs.2026.103106","url":null,"abstract":"","PeriodicalId":9206,"journal":{"name":"Brain Stimulation","volume":"19 3","pages":"Article 103106"},"PeriodicalIF":8.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147762891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Just a caffeine-blocker? Questioning new proposed core mechanisms of ECT","authors":"Johannes Knabbe ,&nbsp;Alexander Sartorius","doi":"10.1016/j.brs.2026.103108","DOIUrl":"10.1016/j.brs.2026.103108","url":null,"abstract":"","PeriodicalId":9206,"journal":{"name":"Brain Stimulation","volume":"19 3","pages":"Article 103108"},"PeriodicalIF":8.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147762904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epileptic spike and waves induce transient lapses of neural excitability","authors":"G. Furregoni ,&nbsp;F.M. Zauli ,&nbsp;S. Valenzano ,&nbsp;E.P. Mikulan ,&nbsp;M. Rosanova ,&nbsp;M. Massimini ,&nbsp;A. Pigorini ,&nbsp;S. Russo","doi":"10.1016/j.brs.2026.103100","DOIUrl":"10.1016/j.brs.2026.103100","url":null,"abstract":"","PeriodicalId":9206,"journal":{"name":"Brain Stimulation","volume":"19 3","pages":"Article 103100"},"PeriodicalIF":8.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"No seizures observed with 100-Hz intermittent theta burst TMS applied to the dorsolateral prefrontal cortex","authors":"Aaron D. Boes ,&nbsp;Benjamin D. Pace ,&nbsp;Holly Van Den Beldt ,&nbsp;Yasser El-Hattab ,&nbsp;Andrew Foster ,&nbsp;Anthony Pugianto ,&nbsp;Nicholas T. Trapp","doi":"10.1016/j.brs.2026.103107","DOIUrl":"10.1016/j.brs.2026.103107","url":null,"abstract":"","PeriodicalId":9206,"journal":{"name":"Brain Stimulation","volume":"19 3","pages":"Article 103107"},"PeriodicalIF":8.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147762855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The lack of efficacy of high-definition transcranial direct current stimulation in the five-day training of a difficult visual search task","authors":"Gorana Pobric,&nbsp;Stephen Ball,&nbsp;Mica Komarnyckyj,&nbsp;Jason R. Taylor,&nbsp;Johan Hulleman","doi":"10.1016/j.brs.2026.103110","DOIUrl":"10.1016/j.brs.2026.103110","url":null,"abstract":"","PeriodicalId":9206,"journal":{"name":"Brain Stimulation","volume":"19 3","pages":"Article 103110"},"PeriodicalIF":8.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147762917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Driving theta-gamma oscillations modulates short interval intracortical inhibition: a tACS-TMS study","authors":"Camille Lasbareilles ,&nbsp;Valentina Mancini ,&nbsp;Alek Pogosyan ,&nbsp;Helen Zhang ,&nbsp;Charlotte Austin ,&nbsp;Huiling Tan ,&nbsp;Charlotte J. Stagg","doi":"10.1016/j.brs.2026.103115","DOIUrl":"10.1016/j.brs.2026.103115","url":null,"abstract":"","PeriodicalId":9206,"journal":{"name":"Brain Stimulation","volume":"19 3","pages":"Article 103115"},"PeriodicalIF":8.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147833709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}