Brain and Behavior最新文献

{"title":"Investigation of the Relationship Between Sensory Processing Skills and Language Development in Children With Developmental Language Disorders","authors":"Elife Barmak,&nbsp;Banu Baş","doi":"10.1002/brb3.70105","DOIUrl":"10.1002/brb3.70105","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The aim was to compare the sensory processing skills of children diagnosed with developmental language disorder (DLD) with those of typically developing children and to investigate the relationship between language development and sensory processing skills.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The investigation comprised 60 children, all of whom were typically developing and diagnosed with DLD. The “Early Language Development-Third: Turkish (ELD: Turkish)” and the “Sensory Profile (Caregiver Questionnaire)” were utilized to assess the language and sensory processing skills of the children, respectively, within the scope of the study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In our study, the four-factor scores of children with DLD were considerably lower than those of their typically developing peers (<i>p</i> &lt; 0.05). These factors are sensory seeking, inattention/distractibility, fine motor/perceptual, and emotionally reactive. In addition, the children with DLD had statistically significant lower scores in three quadrants except for sensory sensitivity (<i>p</i> &lt; 0.05). In three quadrants (sensation seeking, low registration, and sensory avoiding) and three factors (sensory seeking, inattention/distractibility, and fine motor/perceptual), a substantial correlation was observed between the sensory processing skills and the language skills.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>It has been observed that there are differences in the sensory processing skills of children with DLD. In addition to evaluating the language skills of these children, it will also contribute to the evaluation of the effectiveness of their sensory processing skills and the development of more effective strategies in the intervention processes of these children.</p>\u0000 </section>\u0000 </div>","PeriodicalId":9081,"journal":{"name":"Brain and Behavior","volume":"14 12","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11671344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142892022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Propofol Suppresses Ferroptosis via Modulating eNOS/NO Signaling Pathway to Improve Traumatic Brain Injury","authors":"Zi-Lei Zheng,&nbsp;Xu-Peng Wang,&nbsp;Yu-Fei Hu,&nbsp;Wen-Guang Li,&nbsp;Qi Zhou,&nbsp;Fang Xu,&nbsp;Qiu-Jun Wang","doi":"10.1002/brb3.70187","DOIUrl":"10.1002/brb3.70187","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Purpose&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This study aims to explore the neuroprotective effect of propofol in improving traumatic brain injury (TBI) by inhibiting ferroptosis through the modulation of the endothelial nitric oxide (NO) synthase (eNOS)/NO signaling pathway.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;The GSE173975 dataset was used to analyze the differentially expressed genes between TBI and sham surgery control groups in the short and long term. A TBI model was established in 2-month-old male SPF C57BL/6 mice by impact exposure of the exposed dura mater. After the establishment of the TBI model, propofol (30 mg/kg) or saline was administered via intraperitoneal injection for intervention. Nissl staining and Perls staining were employed to assess neuronal function and iron deposition, respectively. Western blot technology was employed to detect the expression of proteins related to ferroptosis. Immunofluorescence staining of astrocytes and microglia was utilized to assess the neuroinflammatory response induced by TBI. The Morris water maze (MWM) and novel object recognition (NOR) tests were employed to assess cognitive dysfunction induced by TBI.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Findings&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Bioinformatics analysis revealed aberrant gene expression associated with iron transport, neuronal death, and inflammatory response in the initial stages of TBI. Long-term abnormalities were predominantly linked to genes involved in inflammatory response. Perls staining and protein expression analysis confirmed the occurrence of iron deposition and ferroptosis following TBI. Propofol treatment significantly reduced iron deposition and ferroptosis induced by TBI. Nissl staining demonstrated enhanced neuronal function, while TUNEL staining indicated reduced neuronal apoptosis. Immunofluorescence analysis demonstrated that propofol significantly reduced the proliferation of astrocytes and activation of microglia induced by TBI in the long term. The results of MWM and NOR tests indicated that propofol significantly improved the long-term cognitive dysfunction induced by TBI. Propofol exerts neuroprotective effects by increasing the expression of eNOS protein and the content of NO. The neuroprotective effects of propofol can be reversed by the eNOS inhibitor L-NAME.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusion&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Propofol significantly improves the prognosis of TBI by inhibiting ferroptosis through the modulation of the eNOS/NO signaling pathway. The study results provide a scientific basis for the clinical use of propofol as a neuroprotective agent a","PeriodicalId":9081,"journal":{"name":"Brain and Behavior","volume":"14 12","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11671348/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142892024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Causal Relationship Between the Abuse of Cholesterol-Lowering Medication, Blood Pressure Medication, Insulin, and Exogenous Hormones and Cerebral Infarction","authors":"Jing Liu,&nbsp;Dongsheng Lv,&nbsp;Shiduo Li,&nbsp;Zhansen An,&nbsp;Zefeng He,&nbsp;Yingzi Liu","doi":"10.1002/brb3.70186","DOIUrl":"10.1002/brb3.70186","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Background&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Cholesterol-lowering medications, blood pressure medication, insulin, and exogenous hormones (including hormone replacement therapy, oral contraceptives, and minipills) are commonly utilized in clinical practice. Recent studies indicate that the use of these medications may significantly influence the occurrence and progression of cerebral infarction. This study aims to investigate the relationship between these medications and cerebral infarction using Mendelian randomization (MR) analysis, with the goal of offering valuable insights for the clinical management of cerebral infarction.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods:&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;To explore the correlation between cholesterol-lowering medication, blood pressure medication, insulin, exogenous hormones, and cerebral infarction, relevant single nucleotide polymorphisms (SNPs) were extracted from the genome-wide association study (GWAS) database. Methods for univariate MR analysis include inverse variance weighting (IVW), the weighted median method, and the MR-Egger method, with IVW being the predominant approach. Subsequently, multivariable Mendelian randomization (MVMR) was conducted on the positive results obtained from the IVW analysis to verify the independent effect of each positive exposure, with IVW still predominating. The causal relationship between this class of drugs and cerebral infarction was evaluated using odds ratio (OR) and 95% confidence interval (CI). MR-PRESSO was used to test for pleiotropy. The robustness of the findings was assessed through leave-one-out analysis, Cochran's &lt;i&gt;Q&lt;/i&gt; test, and funnel plot.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results:&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Univariate MR results indicated that the use of blood pressure medication, insulin, and cholesterol-lowering medication was significantly associated with the occurrence of cerebral infarction (all &lt;i&gt;p&lt;/i&gt; &lt; 0.05). However, due to the stringent inclusion criteria for SNPs, the number of available SNPs is insufficient to elucidate the association between exogenous hormone drugs, contraceptives, and cerebral infarction. Furthermore, the MVMR analysis, which builds upon univariate MR, only identified significant causal associations between blood pressure medication, insulin, and cerebral infarction (&lt;i&gt;p&lt;/i&gt; &lt; 0.05). The association between cholesterol-lowering medication and cerebral infarction was confounded by other positive exposures and did not demonstrate a significant causal relationship when only its independent effects were considered. After integrating the findings from both univariate and MVMR and controlling for confounding variables to the greatest extent possible, the avail","PeriodicalId":9081,"journal":{"name":"Brain and Behavior","volume":"14 12","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663836/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142876070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Community Participation in Native American and White Individuals After Traumatic Brain Injury: A 5-Year Longitudinal Model Systems Study","authors":"Jack D. Watson,&nbsp;Paul B. Perrin,&nbsp;Bridget Xia,&nbsp;Juan Carlos Arango-Lasprilla","doi":"10.1002/brb3.70195","DOIUrl":"10.1002/brb3.70195","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose/Objective</h3>\u0000 \u0000 <p>This study examined (a) differences in demographic and injury-related characteristics following traumatic brain injury (TBI) between Native American and White individuals; (b) differences in community participation between Native American and White individuals with TBI at 1, 2, and 5 years after TBI; and (c) whether demographic or injury-related characteristics account for community participation disparities.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Research Method/Design</h3>\u0000 \u0000 <p>A sample of 63 Native American individuals demographically matched to 63 White individuals (<i>n</i> = 126) was enrolled while on acute rehabilitation for moderate or severe TBI. Baseline demographic and injury-related characteristics were collected at this time and the Participation Assessment with Recombined Tools (PART-O) measure of community participation at 1, 2, and 5 years after TBI.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Native American individuals were less likely to have private insurance and be employed at the time of injury and more likely to have had lower educational attainment and engaged in binge drinking in the month prior to TBI compared to White individuals. Native American individuals demonstrated lower Out and About scores but statistically equivalent Social and Productivity scores. The difference in Out and About scores did not change as a function of time, and the overall difference between the two groups dissipated with the inclusion of statistically different sociodemographic variables.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions/Implications</h3>\u0000 \u0000 <p>Clinicians can provide culturally sensitive, patient- and family-centered care by conducting comprehensive interviews and identifying strengths as well as risk factors that enhance or hinder community participation after TBI in Native American individuals.</p>\u0000 </section>\u0000 </div>","PeriodicalId":9081,"journal":{"name":"Brain and Behavior","volume":"14 12","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11664037/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142876074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seasonal Variations in Triptan Prescription in Japan: A Nationwide Time-Series Analysis","authors":"Muneto Tatsumoto,&nbsp;Koichi Hirata,&nbsp;Takeo Nakayama,&nbsp;Kentaro Yamato,&nbsp;Hiromi Sano,&nbsp;Lyo Inuyama","doi":"10.1002/brb3.70184","DOIUrl":"10.1002/brb3.70184","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study aimed to investigate seasonal differences in migraine onset in Japan and associated trends in the prescription of triptan.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The relationship between seasonal changes and the onset of migraine remains largely unknown.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We combined the large-scale medical claims data in Japan with city-level meteorological data presented by the Japan Weather Association. The study period was from January 2018 to December 2019. We included patients aged 18–74 years and diagnosed with migraine who had been prescribed triptans in 2018. Patients were categorized into four groups according to the seasons when they were prescribed medicines: winter (January–March), spring (April–June), summer (July–September), and autumn (October–December). Migraine onsets were defined by the time of triptan prescription. The least-square mean differences between the seasons were estimated with linear mixed-effects models for repeated measures, adjusting for the following covariates: sex, age, acute migraine medications, and medications for migraine prevention, comorbidities that can induce migraine, other comorbidities, and the estimated age of menopause in females.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>We analyzed data of 12,986 patients in 2019 after triptan had been prescribed (female 74.1%). The mean age was 44.1 years. The mean number of amounts of prescriptions comprised 2.12 tablets/month in spring and summer, whereas there were only 2.09 tablets/month in autumn and 2.00 tablets/month in winter. The amount of triptan prescribed in winter was lower than in spring (<i>β</i> = −0.117; 95% confidence interval [CI]: −0.169 to −0.065).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The study results suggest that seasons can have an impact on the onset of migraine; thus, clinicians may advise patients to take preventive actions, including self-care and drug therapies, from the winter stage. This should be done in order to reduce the number of migraine onsets in high-risk season (spring) regardless of region.</p>\u0000 </section>\u0000 </div>","PeriodicalId":9081,"journal":{"name":"Brain and Behavior","volume":"14 12","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663837/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142876042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Randomized Controlled Trial of Mindfulness Meditation Combined With BrainLink Intelligent Biofeedback Instrument on Pancreatic Cancer Patients Under Chemotherapy","authors":"Na Mi,&nbsp;Shu-Ting Zhang,&nbsp;Xiao-Li Sun,&nbsp;Ting Li,&nbsp;Yu Liao,&nbsp;Lei Dong,&nbsp;Ling-Ling Chu","doi":"10.1002/brb3.70197","DOIUrl":"10.1002/brb3.70197","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Background&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Adjuvant chemotherapy can promote the 5-year overall survival rate of pancreatic cancer (PC) patients to 16%–21%. However, the negative emotions of patients, such as anxiety, are usually omitted. Moreover, their disease burden concentrates on pain symptoms, seriously affecting the quality of life of patients. How to improve the negative emotions of PC patients, alleviate their pain, and ameliorate their quality of life has become an urgent issue.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Objective:&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;To explore the effect of mindfulness meditation (MM) combined with the BrainLink intelligent biofeedback instrument on the anxiety, pain, brain fatigue, and quality of life of PC patients under chemotherapy.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Method:&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;A total of 145 PC patients under chemotherapy were admitted to the Department of Hepatobiliary Surgery of the Second Affiliated Hospital of Army Military Medical University from January 2022 to March 2024 and were incorporated as study objects. They were divided into a control group (&lt;i&gt;n&lt;/i&gt; = 72) and a test group (&lt;i&gt;n&lt;/i&gt; = 73) according to the random number table. The control group received routine nursing treatment; the experimental group was treated with MM combined with an intelligent biofeedback instrument. The general information, anxiety (SAS), pain (VAS), EEG signal data (degrees of fatigue, concentration, and relaxation and EEG waves), and quality of life (EORTC QLQ-C30) of the two groups before intervention and 4th, 8th, and 12th weeks after intervention were compared.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Result&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;There is no significant difference in baseline data and pathological features between the two groups. After the 4th, 8th, and 12th weeks of intervention, the SAS values of the experimental group are remarkably lower than those of the control group (&lt;i&gt;p &lt;/i&gt;&lt; 0.05). In the 4th, 8th, and 12th weeks of intervention, the VAS scores of the experimental group are apparently lower than those of the control group (&lt;i&gt;p &lt;/i&gt;&lt; 0.05). In the 4th, 8th, and 12th weeks of intervention, the score of the quality of life (EORTC QLQ-C30) in the experimental group is significantly higher than that in the control group (&lt;i&gt;p &lt;/i&gt;&lt; 0.05). In the 4th, 8th, and 12th weeks, compared with the control group, the experimental group patients showed significant improvement in brain fatigue relief, concentration, and relaxation levels (&lt;i&gt;p &lt;/i&gt;&lt; 0.05), while the experimental group's brain α and θ. The wave showed an upward trend (&lt;i&gt;p &lt;/i&gt;&lt; 0.05).&lt;/p&gt;\u0000 ","PeriodicalId":9081,"journal":{"name":"Brain and Behavior","volume":"14 12","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11664036/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142876055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship of Neutrophil Percentage-to-Albumin Ratio With Stroke: Evidence From NHANES 1999–2020","authors":"Shuying Xu,&nbsp;Yiyan Sun,&nbsp;Siyao Zhang,&nbsp;Yongjun Peng,&nbsp;Dechun Dai,&nbsp;Leiyong Zhao","doi":"10.1002/brb3.70192","DOIUrl":"10.1002/brb3.70192","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>The objective of this research is to examine the association between neutrophil percentage-to-albumin ratio (NPAR) and stroke, providing a reference for the prevention and prognosis of clinical stroke.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>The study included 56,566 participants from the National Health and Nutrition Examination Survey (NHANES) to explore the association between NPAR and stroke using logistic regression and restricted cubic splines. Upon identifying the nonlinear relationship, inflection points were calculated using recursive algorithms and two-stage linear regression models. Stratified analyses and interaction tests examined variations across population groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>After adjusting for confounders, NPAR was positively associated with stroke (OR: 1.09, 95% CI: 1.05–1.12). Restricted cubic spline analysis indicated a nonlinear trend. Beyond the inflection point, the increasing trend of stroke incidence with higher NPAR levels began to slow down. This relationship remained nonlinear in males but was linear in females.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This study revealed a nonlinear positive association between NPAR and stroke, with higher NPAR increasing the risk of stroke.</p>\u0000 </section>\u0000 </div>","PeriodicalId":9081,"journal":{"name":"Brain and Behavior","volume":"14 12","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11664043/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142876095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reliability and Validity of the Turkish Version of the Acute Stroke Management Questionnaire","authors":"Öznur Adadıoğlu,&nbsp;Bilgehan Atılgan Acar,&nbsp;Türkan Acar","doi":"10.1002/brb3.70191","DOIUrl":"10.1002/brb3.70191","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>The current research was carried out to test the validity and reliability of the Turkish version of the Acute Stroke Management Questionnaire (ASMaQ), developed to determine the acute stroke management awareness of health-care professionals.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This methodological study was performed in a training and research hospital. Data were collected using the “Participant Interview Form” and the Acute Stroke Management Questionnaire.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The Content Validity Index (CVI) of the Acute Stroke Management Questionnaire was found to be 0.91. As a result of exploratory factor analysis (EFA), it was revealed that the scale, which was adapted to Turkish, consisted of 3-factor and 29 items, as in its original form. Confirmatory factor analysis confirmed the 3-factor structure of the scale. The ASMaQ exhibited strong internal consistency (Cronbach's alpha 0.96) and test–retest reliability (0.879).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The 29-item and three-dimensional structure of the Acute Stroke Management Questionnaire was revealed to be a valid and reliable measurement tool that could be utilized in evaluating the acute stroke management awareness of health-care professionals in the Turkish language and culture.</p>\u0000 </section>\u0000 </div>","PeriodicalId":9081,"journal":{"name":"Brain and Behavior","volume":"14 12","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11664040/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142876098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Efficacy of Neurofeedback Interventions for Attention-Deficit/Hyperactivity Disorder in Children: A Network Meta-Analysis","authors":"Gang Wu,&nbsp;Qiang He,&nbsp;Da Li,&nbsp;Zhang Zhang,&nbsp;Jinli Miao,&nbsp;Yanping Shu","doi":"10.1002/brb3.70194","DOIUrl":"10.1002/brb3.70194","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study aimed to synthesize and encapsulate findings from recent research (May 1, 2018 to August 1, 2023) on neurofeedback interventions for children diagnosed with attention deficit hyperactivity disorder (ADHD).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A comprehensive search was conducted across major databases and platforms, including randomized controlled trials s focusing on children aged 5–11 years with ADHD. The inclusion was broad, not restricted by ADHD subtype, gender, IQ, socioeconomic status, or coexisting conditions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>From the study screening process, 13 studies were included in the network meta-analysis, involving 1370 children. Most neurofeedback therapies surpassed placebo in ADHD symptoms. In the acceptability outcome, five neurofeedback therapies (HEG, SCP training, TBR training, SMR training, and active control) outperformed the inactive control, physical activity, and EMG therapies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The potential efficacy of nonpharmacological interventions in ADHD management among children is illuminated. The findings advocate for a holistic, child-centered approach, emphasizing the need for further in-depth research to understand and refine these interventions.</p>\u0000 </section>\u0000 </div>","PeriodicalId":9081,"journal":{"name":"Brain and Behavior","volume":"14 12","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11664034/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142876077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Antagonism Hypothesis: A New View on the Emergence of Consciousness","authors":"Weirui Xiong,&nbsp;Lu Yu","doi":"10.1002/brb3.70201","DOIUrl":"10.1002/brb3.70201","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>The generation of consciousness poses a complex scientific challenge. Neuroscience and biological sciences have extensively studied this phenomenon, yielding numerous theories and hypotheses. However, to date, no reliable evidence has emerged to exclude any hypothesis conclusively, nor has any theory garnered unanimous agreement. This study aims to offer novel insights for further in-depth study on consciousness.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>A new theoretical hypothesis was proposed based on reviews and comments from predictive processing theory, information theory, thermodynamics, and neuroscience.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Findings</h3>\u0000 \u0000 <p>This study argues that, first, it is necessary to clarify that the core implication of the concept of consciousness is first-person perception. Accordingly, the study of consciousness is based on this premise. Second, on this basis, the antagonistic hypothesis of consciousness generation was proposed. This hypothesis holds that consciousness arises from the antagonism of mature individual experiences that cannot be seamlessly integrated with the function of addressing and navigating these conflicts.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The antagonism hypothesis is a new concept regarding the generation of consciousness that deserves further study.</p>\u0000 </section>\u0000 </div>","PeriodicalId":9081,"journal":{"name":"Brain and Behavior","volume":"14 12","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11664041/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142876158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}