BMC Ophthalmology最新文献_第6页

Long-term changes in classified higher-order aberrations after implanting an EVO intraocular collamer lens.

IF 1.7 4区医学

BMC Ophthalmology Pub Date : 2025-03-17 DOI: 10.1186/s12886-025-03932-0

Xun Chen, Huamao Miao, Boliang Li, Mingrui Cheng, I-Chun Lin, Yadi Lei, Yinjie Jiang, Xiaoying Wang, Xingtao Zhou

{"title":"Long-term changes in classified higher-order aberrations after implanting an EVO intraocular collamer lens.","authors":"Xun Chen, Huamao Miao, Boliang Li, Mingrui Cheng, I-Chun Lin, Yadi Lei, Yinjie Jiang, Xiaoying Wang, Xingtao Zhou","doi":"10.1186/s12886-025-03932-0","DOIUrl":"10.1186/s12886-025-03932-0","url":null,"abstract":"Purpose: To evaluate changes in intraocular, corneal, and whole-eye higher-order aberrations (HOAs) after EVO intraocular collamer lens (ICL) implantation.Methods: In this retrospective study, we enrolled 53 eyes of 53 patients and measured their refractive parameters and intraocular, corneal, and whole-eye HOAs using OPD scanning preoperatively and 1 month, and 3 years postoperatively. All statistical analyses were performed using SPSS software.Results: The safety index was 1.31 ± 0.15, and the efficacy index was 1.02 ± 0.24 3 years postoperatively. The best linear fit curve of the attempted versus achieved correction was y = 0.96x + 0.08 at 3 years postoperatively. The mean spherical equivalent decreased from - 8.53 ± 2.49 D preoperatively to -0.09 ± 0.25 D and - 0.34 ± 0.41 D at 1 month and 3 years postoperatively, respectively (P < 0.05). The whole-eye trefoil and total HOAs, intraocular trefoil, corneal trefoil increased significantly at 1 month (P < 0.05) but did not change significantly at 3 years (P > 0.05) postoperatively compared to the preoperative value. The intraocular spherical aberration and total HOAs increased significantly at 1 month and 3 years postoperatively (P < 0.05). The whole-eye coma or spherical aberration, intraocular coma, corneal coma or spherical aberration or total HOAs did not differ from those observed at 1 month and 3 years postoperatively (P > 0.05).Conclusions: Long-term EVO-ICL implantation is safe, effective, predictable, and stable. The intraocular and corneal trefoils increased significantly in the early postoperative period but can be recovered to the preoperative level in the long term. The intraocular spherical aberration increases slightly in the long term postoperatively, but the whole-eye spherical aberration does not change significantly.","PeriodicalId":9058,"journal":{"name":"BMC Ophthalmology","volume":"25 1","pages":"138"},"PeriodicalIF":1.7,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11916164/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optic neuritis, as unusual manifestations of hypoparathyroidism: a rare case report.

IF 1.7 4区医学

BMC Ophthalmology Pub Date : 2025-03-14 DOI: 10.1186/s12886-025-03957-5

Yousef Mirmazloomi, Forough Ebrahimtabar, Hossein Mozhdehipanah

{"title":"Optic neuritis, as unusual manifestations of hypoparathyroidism: a rare case report.","authors":"Yousef Mirmazloomi, Forough Ebrahimtabar, Hossein Mozhdehipanah","doi":"10.1186/s12886-025-03957-5","DOIUrl":"10.1186/s12886-025-03957-5","url":null,"abstract":"Background: Optic neuritis, commonly associated with multiple sclerosis (MS), can also occur in the context of hypocalcemia as a rare intriguing clinical scenario. Most recent articles have reported the association of papilledema and hypoparathyroidism, However, very rarely, case reports revealed hypocalcemia-induced optic neuritis as well as our case.Case presentation: We report a 43-year-old woman with a history of hypocalcemia presenting with optic neuritis, characterized by sudden vision loss, painful eye movements, and pulsatile headache. Despite the normalization of serum calcium level and pulses of steroid treatment for the most probable underlying cause (demyelination); visual acuity improvement was not regained. Lumbar puncture revealed normal intracranial pressure, and MRI showed unspecific periventricular signal changes with T1 hyperintensity in bilateral basal ganglia and thalamic mostly in favor of calcifications. Additional investigations ruled out alternative conditions like multiple sclerosis and other inflammatory-based disorders.Discussion: Optic neuritis could have an association with hypocalcemia, with or without elevated intracranial pressure, which highlights the necessity for comprehensive evaluations in patients with visual symptoms despite normal intracranial pressure. While serum calcium correction effectively treats papilledema, its benefit for optic neuritis remains unclear. Further evaluations are needed to understand the exact pathology and optimal management of hypocalcemia-related optic neuritis.","PeriodicalId":9058,"journal":{"name":"BMC Ophthalmology","volume":"25 1","pages":"134"},"PeriodicalIF":1.7,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11907986/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anterior ischemic optic neuropathy in patients treated with semaglutide: report of four cases with a possible association.

IF 1.7 4区医学

BMC Ophthalmology Pub Date : 2025-03-14 DOI: 10.1186/s12886-025-03958-4

Hamid Ahmadi, Steffen Hamann

{"title":"Anterior ischemic optic neuropathy in patients treated with semaglutide: report of four cases with a possible association.","authors":"Hamid Ahmadi, Steffen Hamann","doi":"10.1186/s12886-025-03958-4","DOIUrl":"10.1186/s12886-025-03958-4","url":null,"abstract":"Background: Semaglutide, a glucagon-like peptide-1 receptor agonist, is increasingly used worldwide for its cardiometabolic benefits. However, it has recently been associated with nonarteritic anterior ischemic optic neuropathy (NAION). This report presents four clinical cases and explores a possible association.Case presentation: Four male patients were diagnosed with NAION during semaglutide treatment, with treatment durations of less than one year in three cases. All presented with significant optic disc edema and intraretinal fluid on optical coherence tomography, along with crowded optic disc and small Bruch's membrane opening diameters (< 1.4 mm in three cases). One patient exhibited optic disc drusen. Visual field defects corresponded with ganglion cell layer atrophy on optical coherence tomography. Systemic risk factors varied; two patients had only obesity.Conclusions: Our observation suggests that individuals with small Bruch's membrane opening diameter may be at risk of developing NAION during semaglutide treatment.","PeriodicalId":9058,"journal":{"name":"BMC Ophthalmology","volume":"25 1","pages":"132"},"PeriodicalIF":1.7,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11908077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Systemic and localized infections in humans caused by Paenibacillus: a case report and literature review.

IF 1.7 4区医学

BMC Ophthalmology Pub Date : 2025-03-14 DOI: 10.1186/s12886-025-03966-4

Shuwen Lu, Haoyu Li, Chao Ma, Xian Li

{"title":"Systemic and localized infections in humans caused by Paenibacillus: a case report and literature review.","authors":"Shuwen Lu, Haoyu Li, Chao Ma, Xian Li","doi":"10.1186/s12886-025-03966-4","DOIUrl":"10.1186/s12886-025-03966-4","url":null,"abstract":"Background: As opportunistic pathogens, Paenibacillus organisms rarely induce human infections. This research paper details the clinical manifestations, treatment, and prognosis of an intraocular infection caused by Paenibacillus in a 43-year-old male patient.Case presentation: In this case, the patient initially presented with persistent ocular redness and a sensation of foreign bodies following trauma surgery. Upon admission, we performed intraocular fluid metagenomic next generation sequencing (mNGS) testing and systemic blood sampling for infection-related assessments. The results revealed a localized ocular infection with Paenibacillus organisms. Consequently, the patient received daily levofloxacin injections (500 mg) and clindamycin (300 mg) for systemic anti-infective therapy, along with subconjunctival injections of gentamicin (2 WIU) and dexamethasone (5 mg) for topical application. The infection was effectively managed, and their ocular symptoms showed improvement during the treatment course.Conclusions: We conducted a comprehensive review of previously reported cases involving Bacillus-like organisms causing human infections, exploring mechanisms, diagnostic approaches, and treatment strategies.","PeriodicalId":9058,"journal":{"name":"BMC Ophthalmology","volume":"25 1","pages":"133"},"PeriodicalIF":1.7,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11907811/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute retinal necrosis following cataract surgery: a case of VZV reactivation and successful management. 白内障手术后急性视网膜坏死：一例 VZV 再激活病例及成功治疗。

IF 1.7 4区医学

BMC Ophthalmology Pub Date : 2025-03-14 DOI: 10.1186/s12886-025-03950-y

Ting Luo, Lu Wang, Li Zhang, Ming-Jue Hu, Si-Rui Zhou, Xing-Yu He, Jun-Feng Yang

{"title":"Acute retinal necrosis following cataract surgery: a case of VZV reactivation and successful management.","authors":"Ting Luo, Lu Wang, Li Zhang, Ming-Jue Hu, Si-Rui Zhou, Xing-Yu He, Jun-Feng Yang","doi":"10.1186/s12886-025-03950-y","DOIUrl":"10.1186/s12886-025-03950-y","url":null,"abstract":"Background: Acute retinal necrosis triggered by routine cataract surgery is a rare condition, which may be overlooked by the clinicians. We report a case of unilateral acute retinal necrosis (ARN) with the onset 4 days after uncomplicated cataract surgery. The patient demonstrates satisfactory outcomes following anti-virus therapy.Case presentation: A 73-year-old male presenting with 1-day history of floaters, eye redness, pain and vision loss in his right eye was referred to our clinic. He had just completed uncomplicated phacoemulsification and posterior chamber intraocular lens implantation in the right eye 5 days ago. He had a history of cutaneous herpes zoster infection at the age of 40. The visual acuity was counting fingers in the right eye at presentation with marked anterior and posterior segment inflammation. ARN was suspected based on fundus findings, including retinal hemorrhage, vessel attenuation and retinal whitening. Following anti-virus therapy, the inflammation and visual acuity improved. Aqueous humor for viral DNA testing using polymerase chain reaction showed positivity to varicella zoster virus (VZV), confirming the diagnosis of VZV associated ARN. The visual acuity improved to 18/20 at one month follow-up examination with no recurrence of inflammation.Conclusions: Clinicians should be aware of the possibility of cataract surgery as a triggering event for reactivation of VZV and subsequent ARN. Anti-virus therapy initiated at early phase of the disease may yield satisfactory visual outcomes for the patient. Careful preoperative screening and postoperative monitoring in patients with a history of herpes infection is important.","PeriodicalId":9058,"journal":{"name":"BMC Ophthalmology","volume":"25 1","pages":"131"},"PeriodicalIF":1.7,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11907935/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Malignant melanoma of the conjunctiva metastasizing to the submandibular gland: a case report and review of the literature.

IF 1.7 4区医学

BMC Ophthalmology Pub Date : 2025-03-13 DOI: 10.1186/s12886-025-03949-5

Chigozie C Okongwu, Bolajoko Abidemi Adewara, Olaejirinde O Olaofe, Ademola I Soremekun, Samuel O Ayodele, Yusuf O Abdullahi, Ese E Ewoye, James O Oladele

{"title":"Malignant melanoma of the conjunctiva metastasizing to the submandibular gland: a case report and review of the literature.","authors":"Chigozie C Okongwu, Bolajoko Abidemi Adewara, Olaejirinde O Olaofe, Ademola I Soremekun, Samuel O Ayodele, Yusuf O Abdullahi, Ese E Ewoye, James O Oladele","doi":"10.1186/s12886-025-03949-5","DOIUrl":"10.1186/s12886-025-03949-5","url":null,"abstract":"Background: Conjunctival malignant melanoma is an aggressive tumor with the potential for metastasis and death. It is rare in the black population because of the protective effect of melanin. Metastases are usually to regional lymph nodes, most commonly the preauricular nodes, deep cervical lymph nodes, and the salivary gland.Case presentation: We described the case of a 41-year-old black African woman who presented to our ophthalmology clinic with a painless, right medial pigmented bulbar conjunctival swelling and right preauricular and submandibular swelling. Two years ago, she had similar swelling at the same location in the right eye. She subsequently underwent surgical excision under general anesthesia. Histology of both tissues showed proliferating malignant melanocytes that showed heavy pigmentation disposed of in solid nests, tongues, and sheets obscuring cellular details in these areas. Immunohistochemistry showed tumor cells to stain for HMB45 and Melan A. This led us to conclude that the tumor was a malignant melanoma. The patient died a year after making the diagnosis.Conclusion: Conjunctival melanoma is a rare ocular malignancy that should be considered in cases of pigmented lesions of the eye, especially in people with dark pigmentation. Primary acquired melanosis with atypia or a nevus are known as preexisting melanocytic lesions from which conjunctival melanomas might develop. Metastases are often to preauricular and cervical lymph nodes as well as to the salivary gland. This demonstrates the significance of early presentation, thorough history taking, physical examination, and surgical excision for histopathology.","PeriodicalId":9058,"journal":{"name":"BMC Ophthalmology","volume":"25 1","pages":"130"},"PeriodicalIF":1.7,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11905526/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on: "Astigmatism in Duane Retraction Syndrome".

IF 1.7 4区医学

BMC Ophthalmology Pub Date : 2025-03-12 DOI: 10.1186/s12886-025-03952-w

Hajar Farvardin, Majid Farvardin

引用次数: 0

Agreement between swept-source OCT and Scheimpflug biometers in ocular measurements.

IF 1.7 4区医学

BMC Ophthalmology Pub Date : 2025-03-12 DOI: 10.1186/s12886-025-03916-0

Cameron McLintock, James McKelvie, Hamed Niyazmand, Samir Uprety

{"title":"Agreement between swept-source OCT and Scheimpflug biometers in ocular measurements.","authors":"Cameron McLintock, James McKelvie, Hamed Niyazmand, Samir Uprety","doi":"10.1186/s12886-025-03916-0","DOIUrl":"10.1186/s12886-025-03916-0","url":null,"abstract":"Background: This study evaluated the agreement of the ocular parameters obtained with the two optical biometers, the IOLMaster 700 and the Galilei G6 Lens Professional.Patients and methods: A comparative prospective study was conducted on 159 eyes of 91 adult patients using the IOLMaster 700 and Galilei G6 devices by a single examiner. Agreement between ocular biometric parameters: white-to-white (WTW) distance, keratometry (flat (K1) and steep (K2), mean (Km)) of anterior, posterior, and total corneal surfaces, central corneal thickness (CCT), anterior chamber depth (ACD), and axial length (AL) were assessed using Bland-Altman analysis. Keratometry measurements were further transformed into power vector components J0 and J45 for astigmatism analysis. Clinically significant differences were defined as deviations in biometric parameters translating to differences of 0.25 D or more in refractive outcomes.Results: Statistically and clinically significant difference was identified for ACD (mean difference: -0.15 mm), posterior corneal metrics: K1 (0.39 D), K2 (0.42 D), Km (0.41 D) and J0 (0.05 D) and total corneal metrics: K1 (0.95 D), K2 (0.91 D), Km (0.93 D) and J0 (0.13 D). No significant differences were found for J45 components of posterior and total K, WTW, CCT, and AL measurements.Conclusion: The difference in measurements of anterior chamber depth (ACD), posterior K, and total K metrics are clinically significant making the two devices are clinically significant and not interchangeable. These variation in metrics can impact the refractive outcomes of refractive and cataract surgery with toric IOLs.","PeriodicalId":9058,"journal":{"name":"BMC Ophthalmology","volume":"25 1","pages":"127"},"PeriodicalIF":1.7,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11905573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143613272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful treatment of choroidal hemangiomas in Sturge-Weber syndrome using external beam radiotherapy.

IF 1.7 4区医学

BMC Ophthalmology Pub Date : 2025-03-12 DOI: 10.1186/s12886-025-03941-z

Ting-Wei Su, I-Ling Chou, Huai-Chin Fan, San-Ni Chen, Chin-Nan Chu

引用次数: 0

Comparative analysis of myopia correction outcomes and aberration changes between PRK and SMILE: A study based on strict refractive criteria.

IF 1.7 4区医学

BMC Ophthalmology Pub Date : 2025-03-12 DOI: 10.1186/s12886-025-03943-x

Bekir Küçük, Mahmut Erkam Arslan, Ender Sırakaya

{"title":"Comparative analysis of myopia correction outcomes and aberration changes between PRK and SMILE: A study based on strict refractive criteria.","authors":"Bekir Küçük, Mahmut Erkam Arslan, Ender Sırakaya","doi":"10.1186/s12886-025-03943-x","DOIUrl":"10.1186/s12886-025-03943-x","url":null,"abstract":"Purpose: To analyze the refractive outcomes and changes in corneal aberrations after PRK and SMILE surgeries, and to compare these two methods.Patients and methods: This retrospective comparative study investigated patients aged 20-40 years who underwent SMILE or PRK for the correction of myopia between - 1.00 D and - 2.00 D, along with a cylindrical power of -0.50 D or lower. Preoperative and 6-month postoperative assessments included uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), and corneal aberrations such as higher-order aberrations (HOA), spherical aberrations (SA), vertical coma (Z3,-1), horizontal coma (Z3,1), oblique trefoil (Z3,-3), and horizontal trefoil (Z3,3).Results: A total of 73 eyes from 73 patients (37 SMILE and 36 PRK) were analysed. Both groups showed significant improvement in UCVA and refractive parameters (p < 0.05), while BCVA remained stable (p > 0.05). Postoperative corneal aberrations increased in both groups, with no significant intergroup differences (p > 0.05).Conclusions: Both SMILE and PRK are effective and safe for the correction of low myopia, with comparable refractive outcomes and visual quality. Despite an increase in corneal aberrations in both techniques, their impact on overall visual performance is similar. Procedure selection should be individualized based on patient-specific factors and lifestyle.","PeriodicalId":9058,"journal":{"name":"BMC Ophthalmology","volume":"25 1","pages":"124"},"PeriodicalIF":1.7,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11900079/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143613229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0