BMC Ophthalmology最新文献

{"title":"Vector analysis valuation of astigmatism in the cornea after femtosecond laser-assisted corneal astigmatism incision in cataract surgery.","authors":"Dan Yang, Shifeng Fang, Yi Yang, Ning Bao, Pin Zuo, Shujie Miao, Xinxia Xue, Jixin Zou","doi":"10.1186/s12886-025-04145-1","DOIUrl":"https://doi.org/10.1186/s12886-025-04145-1","url":null,"abstract":"<p><strong>Background: </strong>The aim of this article is to evaluate the effectiveness of anterior penetrating femtosecond laser-assisted astigmatism keratotomy (FS-AK) using vector analysis.</p><p><strong>Methods: </strong>This retrospective before-after study included 68 patients with corneal astigmatism > 1D who underwent FLACS at Dalian Third People's Hospital between June 2023 and July 2024 as research participants. All patients received monofocal non-spherical intraocular lenses. The femtosecond laser, operated on the Catalys platform (Johnson & Johnson, Santa Ana, CA, USA), utilized the corneal limbus center as a reference point, with an 8 mm cutting range centered on the optical zone and a cutting depth of 80%. The planned penetration type is anterior penetrating. The planned parameters were 20% uncut posterior, and 90°side cut angle. The arc length was calculated and optimized using Dr. Julian Stevens' nomogram. Astigmatism was analyzed using the vector method, incorporating three basic parameters: target-induced astigmatism vector (TIA), surgically induced astigmatism (SIA), and differential vector (DV), and multiple evaluation parameters: error angle (AE), correction index (CI), adjustment coefficient (CA), and flattening index. Data were analyzed by group according to astigmatism type, age, and white-to-white measurement.</p><p><strong>Results: </strong>The 68 patients (76 eyes) had an average TIA of 1.812 ± 0.769 D, an average SIA of 0.865 ± 0.489 D, and an average DV of 0.947 ± 0.777 D. The average AE was - 1.671 ± 28.836, average CI was 0.509 ± 0.259, and average CA was 4.453 ± 7.675, representing a general mild undercorrection. In the subgroup analysis, the cylindrical error correction effect of the against-the-rule astigmatism group was better than that of the with-the-rule astigmatism group, and the correction effect in patients over 60 years was better than that in those under 60 years (P = 0.000). The combined use of FLACS and APAK cylindrical error correction vector analysis showed that there was slight under-correction in both cases.</p><p><strong>Conclusion: </strong>This study demonstrated that femtosecond laser-assisted anterior corneal penetrating arc incision safely and effectively reduced corneal astigmatism after cataract surgery; however, there was an overall under-correction. By conducting a long-term analysis of the APAK results, further studies can help optimize nomogram parameters to improve the precision of femtosecond laser-assisted astigmatism keratotomy cylindrical error correction.</p>","PeriodicalId":9058,"journal":{"name":"BMC Ophthalmology","volume":"25 1","pages":"318"},"PeriodicalIF":1.7,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144172618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of Corynebacterium propinquum microbial keratitis after amniotic membrane transplantation.","authors":"Yuto Yukari, Toshiki Shimizu, Takahiko Hayashi, Yusuke Hara, Ami Igarashi, Satoru Yamagami","doi":"10.1186/s12886-025-04159-9","DOIUrl":"https://doi.org/10.1186/s12886-025-04159-9","url":null,"abstract":"<p><strong>Background: </strong>Amniotic membrane transplantation (AMT) is a relatively safe procedure with few complications. Postoperatively, patients are treated with topical antibacterial eye drops. However, even antibacterial drug administration cannot completely prevent antimicrobial-resistant keratitis. This paper presents a case of Corynebacterium propinquum keratitis associated with AMT.</p><p><strong>Case presentation: </strong>An 84-year-old female patient who underwent AMT for bullous keratopathy developed keratitis with colony formation on the transplanted amniotic membrane graft 45 days postoperatively. The colony was scraped, cultured, and identified as C. propinquum using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS). Subsequently, topical treatment improved the infection while relieving the pain.</p><p><strong>Conclusion: </strong>To the best of our knowledge, this is the first reported case of C. propinquum keratitis associated with amniotic membrane grafts. Although AMT is a relatively safe procedure with few complications, careful observation is required to diagnose and treat possible postoperative infection. Immunosuppressed patients, including those post-AMT, may suffer from antimicrobial-resistant keratitis, necessitating microbial identification and drug susceptibility testing such as MALDI-TOF-MS.</p>","PeriodicalId":9058,"journal":{"name":"BMC Ophthalmology","volume":"25 1","pages":"314"},"PeriodicalIF":1.7,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144156886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and efficacy of rebamipide compared to artificial tears for the treatment of dry eye: a systematic review and meta-analysis.","authors":"Ching-Wen Chiu, Ka-Wai Tam, I-Chan Lin","doi":"10.1186/s12886-025-04146-0","DOIUrl":"https://doi.org/10.1186/s12886-025-04146-0","url":null,"abstract":"<p><strong>Background: </strong>Rebamipide (RBM) is a novel drug that increases mucin secretion on the ocular surface. Nevertheless, the therapeutic efficacy of topical RBM for dry eye disease (DED) treatment remains inconclusive. Accordingly, we conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) investigating the effectiveness of RBM for DED treatment.</p><p><strong>Methods: </strong>We searched the PubMed, Embase, and Cochrane Library databases for eligible RCTs. The primary outcome was posttreatment changes in tear breakup time (TBUT). We also assessed changes in the values of Schirmer's test (Sch), corneal fluorescein staining scores, and DED-related symptom scores.</p><p><strong>Results: </strong>We retrieved 12 RCTs with 1368 eyes published during 2012-2023. The results demonstrated that compared with artificial tears, 2% RBM significantly increased the TBUT [standard mean difference (SMD) = 1.42, 95% confidence interval (CI) = 0.20 to 2.64]. Moreover, 2% RBM led to more significant improvements in overall DED-related symptom scores than did artificial tears (SMD = - 1.61, 95% CI = - 2.61 to - 0.61). The differences in the adverse events between the 2% RBM and artificial tears groups were nonsignificant (SMD = 1.23, 95% CI = 0.62 to 2.44).</p><p><strong>Conclusion: </strong>Topical RBM ophthalmic suspension is a safe and effective treatment for DED patients. Compared to artificial tears, 2% RBM improved TBUT and subjective symptoms of DED. It may be considered as the first-line treatment option for short- TBUT dry eye patients.</p>","PeriodicalId":9058,"journal":{"name":"BMC Ophthalmology","volume":"25 1","pages":"317"},"PeriodicalIF":1.7,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144155823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research on the clinical and pathological characteristics of primary orbital neoplastic lesions with communication.","authors":"Lian Wang, Jing Zhang, Shuo Zhang, Bin Li, Bentao Yang, Hongjuan Liu, Chunli Chen, Qiong Wu, Libin Jiang","doi":"10.1186/s12886-025-04118-4","DOIUrl":"https://doi.org/10.1186/s12886-025-04118-4","url":null,"abstract":"<p><strong>Objective: </strong>To comprehensively summarize the clinical and pathological characteristics of primary orbital neoplastic lesions with communication, thereby providing a solid basis for the diagnosis and treatment of such conditions.</p><p><strong>Method: </strong>A retrospective analysis of clinical cases was conducted. The clinical and pathological data of 862 patients diagnosed with primary orbital neoplasms with communication, including orbito-cranial, orbito-nasal, and orbito-crano-nasal communicating tumors, were collected. The data covered gender distribution, age at onset, presenting symptoms and signs, imaging findings, and treatment modalities. These data were systematically summarized according to pathological diagnoses.</p><p><strong>Results: </strong>Among all primary orbito-related communication neoplasms, meningioma was identified as the most common benign tumor (11.0%, 95/862), with a mean age of onset of 45.3 ± 12.7 years. Notably, 72.6% of meningiomas originated from the orbit, while 27.4% originated from intracranial sites. In contrast, adenoid cystic carcinoma was the most common malignant tumor (9.5%, 82/862), with a mean age of onset of 39.1 ± 12.8 years. The majority of adenoid cystic carcinomas (59.8%) originated from the orbit, whereas 29.3% originated from the sinuses. In the pediatric population under the age of 14 years, a total of 102 cases were identified. Out of these, there were 67 cases of orbito-cranial communication (65.7%), 5 cases of orbito-nasal communication (4.9%), and 30 cases of orbito-crano-nasal communication (29.4%). Optic glioma was the most common benign tumor in pediatric orbito-cranial communication (22.4%, 15/67), with an average age of onset at 5.6 ± 4.2 years. The most prevalent malignant tumor among children with orbito-cranial communication was small round cell tumor (10.4%, 7/67), with an average age of onset at 4.6 ± 3.7 years. In children with orbital-cranio-nasal communication, sarcoma was identified as the most common malignant tumor (43.3%, 13/30), with 76.9% of tumors originating from the nose. The most common benign tumor in this group was nasopharyngeal fibroangioma (16.7%, 5/30), which exclusively affected males and originated from the nasopharynx.</p><p><strong>Conclusion: </strong>The clinical features and pathological classification of primary orbital tumors vary significantly depending on the type of communication. Moreover, there are substantial differences in the pathological subtypes of these orbital lesions between children and adults.</p>","PeriodicalId":9058,"journal":{"name":"BMC Ophthalmology","volume":"25 1","pages":"315"},"PeriodicalIF":1.7,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144156891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alterations in ocular fungal microbiota in patients with fungal keratitis: a comparative study from coastal regions of Eastern China.","authors":"Xudong Zhao, Zhichao Ren, Wenfeng Li, Qing Liu, Yanling Dong, Yusen Huang","doi":"10.1186/s12886-025-04133-5","DOIUrl":"https://doi.org/10.1186/s12886-025-04133-5","url":null,"abstract":"<p><strong>Objective: </strong>The understanding of the ocular microbiota, particularly in fungal keratitis (FK), is evolving with advancements in high-throughput sequencing technologies. Traditional culture-based methods may not fully capture the microbial diversity present in keratitis, highlighting the need for more comprehensive approaches to explore microbial dysbiosis in corneal infections. This study aimed to reveal the dysbacteriosis of the ocular fungal microbiome associated with FK.</p><p><strong>Methods: </strong>We analysed 105 samples, including conjunctival swabs from healthy eyes (HE) and conjunctival swabs (SW), as well as corneal scrapings (SC), from FK eyes. Positive results were observed in 58 samples, and detailed taxonomic categorization was carried out across multiple levels-phylum, class, order, family, and genus-using high-throughput ITS sequencing. Alpha and beta diversity indices were computed, and interaction networks at the genus level were predicted to elucidate changes in microbial communities. The analyses also included assessments of functional groups within the fungal microbiome.</p><p><strong>Results: </strong>Among the samples, the HE, SW, and SC groups presented differences in positivity rates and diversity indices. Compared with HE eyes, infected eyes (SW and SC) presented significantly greater Good's coverage estimator and lower Chao1, Shannon, and Simpson diversity indices, indicating reduced species richness and evenness. At multiple taxonomic levels, various taxa were significantly downregulated in the FK eyes. Functional analyses revealed differences, notably, an increase in the number of litter saprotrophs in FK eyes. Ascomycota and Basidiomycota were identified as core phyla in the ocular microbiota interaction network.</p><p><strong>Conclusion: </strong>Fungal keratitis significantly alters the ocular surface microbiome, which is characterized by decreased microbial richness and evenness. High-throughput sequencing revealed a complex interaction network with significant variability between healthy and infected eyes. Additionally, these findings suggest potential benefits from early and aggressive debridement in managing FK due to its impact on functional microbial groups.</p>","PeriodicalId":9058,"journal":{"name":"BMC Ophthalmology","volume":"25 1","pages":"316"},"PeriodicalIF":1.7,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144156889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of intensive glycemic control on the changes of diabetic retinopathy in type 2 diabetes: a prospective observational cohort study.","authors":"Xinyan Wu, Yayi Yan, Yuntong Li, Yiran Fan, Lingyi Li, Ching-Kit Tsui, Kaiqun Liu, Xiaoling Liang, Wenyong Huang, Andina Hu","doi":"10.1186/s12886-025-04139-z","DOIUrl":"https://doi.org/10.1186/s12886-025-04139-z","url":null,"abstract":"<p><strong>Background: </strong>A large body of evidence supports the long-term benefits of intensive glycemic control for patients with type 2 diabetes mellitus (T2DM). However, the relationship between intensive glycemic control and diabetic retinopathy (DR) progression in T2DM patients in the short-term remains under debate. Therefore, we investigated the effect of intensive glycemic control on DR changes in the short-term.</p><p><strong>Methods: </strong>A total of 254 patients with T2DM, all exhibition hemoglobin A_1c (HbA_1c) levels above 7% were included in the study. We collected HbA_1c values at baseline and after 12-months. HbA_1c control classified into two categories: intensive control, targeting an HbA_1c of less than 7%, and less intensive control, targeting an HbA_1c of 7% or higher at 12-month follow-up. The severity of DR were graded based on seven-field 45° conventional fundus photographs examinations according to the United Kingdom National Diabetic Eye Screening Program guidelines.</p><p><strong>Results: </strong>After a one-year follow-up, 129 participants achieved a target HbA_1c of less than 7% and 125 achieved 7% or more. We found no significant difference in DR changes (incidence, progression, or regression) between two groups after adjustments for age and gender. Further adjustments for confounding factors such as body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), diabetes duration, insulin use and baseline HbA_1c, revealed no association between intensive glycemic control and the DR changes.</p><p><strong>Conclusions: </strong>This prospective cohort study demonstrates that intensive glycemic control did not associated with DR changes in T2DM patients in the short term. Further research is required to ascertain the long-term effects of intensive glycemic control on DR.</p><p><strong>Trial registration: </strong>The trail has been registered at The UK's Clinical Study Registry ( https://www.isrctn.com ) on 2020/04/13 (ISRCTN15853192).</p>","PeriodicalId":9058,"journal":{"name":"BMC Ophthalmology","volume":"25 1","pages":"313"},"PeriodicalIF":1.7,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144149266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing the effects of orthokeratology lenses and highly aspherical lenslets on axial length in myopic anisometropia.","authors":"Minfeng Chen, Xianling Yang, Xibo Yu, Huihui Lei, Xinjie Mao","doi":"10.1186/s12886-025-04134-4","DOIUrl":"10.1186/s12886-025-04134-4","url":null,"abstract":"<p><strong>Purpose: </strong>This study compares the influences of orthokeratology (OK) lenses and highly aspherical lenslets (HAL) on axial length (AL) in myopic anisometropia.</p><p><strong>Methods: </strong>Retrospective analysis was performed on 225 individuals with myopic anisometropia who agreed to wear OK lenses, HAL or single-vision spectacles (SP). Subjects with bilateral myopic anisometropia (BMA) were divided into the following groups: SP-BMA, HAL-BMA and OK-BMA. Further, children with unilateral myopic anisometropia (UMA) were divided into the following groups: SP-UMA, UHAL-UMA (unilateral HAL), BHAL-UMA (bilateral HAL) and OK-UMA (unilateral OK lens). Analyzed the difference in the interocular AL elongation in different groups.</p><p><strong>Results: </strong>For children with BMA, the interocular difference change in the OK-BMA group (0.15 ± 0.19 mm) was greater than that in the SP-BMA (-0.01 ± 0.20 mm) and HAL-BMA (-0.03 ± 0.17 mm) groups, all P < 0.001. For children with UMA, in the non-myopic eyes, the difference in AL elongation in the BHAL-UMA group (0.10 ± 0.14 mm) was less than that in the SP-UMA (0.28 ± 0.22 mm), UHAL-UMA (0.40 ± 0.22 mm) and OK-UMA (0.47 ± 0.24 mm) groups, all P < 0.001. The interocular change in the UHAL-UMA group (0.29 ± 0.36 mm) and OK-UMA group (0.35 ± 0.25 mm) were all higher than that in the SP-UMA (-0.02 ± 0.23 mm) and BHAL-UMA (0.01 ± 0.18 mm) groups, all P < 0.01.</p><p><strong>Conclusions: </strong>OK lenses can effectively reduce the interocular AL difference for children with unilateral or bilateral myopic anisometropia. However, HAL only decreased the interocular AL difference for children with UMA when wearing unilateral HAL but it did slow down the AL elongation of the non-myopic eyes in children with UMA when wearing bilateral HAL.</p>","PeriodicalId":9058,"journal":{"name":"BMC Ophthalmology","volume":"25 1","pages":"312"},"PeriodicalIF":1.7,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12105321/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144141429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posterior optic capture for repositioning of dislocated three-piece intraocular lens: a single center retrospective study.","authors":"Yasuhiko Asano, Hidetoshi Onda","doi":"10.1186/s12886-025-04147-z","DOIUrl":"10.1186/s12886-025-04147-z","url":null,"abstract":"<p><strong>Background: </strong>Intraocular lens (IOL) dislocations represent a serious complication of cataract surgery. In cases of isolated dislocation of a three-piece IOL, the dislocated IOL can be fixed in the ciliary sulcus. However, stability issues arise when the total haptic length does not match the ciliary sulcus distance or when zonular dehiscence causes the IOL to slip into the dehiscence site. Therefore, this study aimed to evaluate the efficacy of posterior optic capture (POC) for repositioning dislocated three-piece IOLs, with haptics fixated in the ciliary sulcus and the optic captured within a posterior capsular window.</p><p><strong>Methods: </strong>The dislocated IOL was first refixed in the ciliary sulcus. A 25-gauge vitrectomy cutter was inserted through the corneal stab incision and positioned between the optic and posterior capsules to create a posterior capsular window with a 4-5 mm diameter. The optic was then pushed into the posterior capsular window and was captured. The surgical outcomes of 13 eyes from 13 patients who were followed for at least 12 months after surgery were retrospectively evaluated based on medical records.</p><p><strong>Results: </strong>The mean time from IOL implantation to POC was 28.3 ± 23.8 months. The mean postoperative follow-up period was 19.9 ± 8.55 months. The mean surgical duration was 14.4 ± 6.8 min. No intraoperative complications were observed. The postoperative best-corrected visual acuity improved or remained unchanged in all patients. The mean change in spherical equivalent before and after surgery was 0.60 ± 0.65 D. The postoperative anterior chamber depth (ACD) was 4.29 ± 0.34 mm, which was increased from the preoperative ACD of 3.86 ± 0.48 mm (p < 0.05). The corneal endothelial cell density loss was 2.28 ± 3.96%. Postoperatively, one patient experienced recurrent IOL dislocation due to enlargement of the zonular dehiscence. In all other cases, slit-lamp examination and anterior segment optical coherence tomography (AS-OCT) confirmed stable IOL positioning and maintained optic capture. At the final visit, IOL decentration and tilt calculated from AS-OCT were 0.35 ± 0.22 mm and 2.68 ± 1.52°, respectively.</p><p><strong>Conclusions: </strong>POC is a minimally invasive and straightforward technique for intermediate-term fixation of dislocated three-piece IOLs.</p>","PeriodicalId":9058,"journal":{"name":"BMC Ophthalmology","volume":"25 1","pages":"308"},"PeriodicalIF":1.7,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12100848/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144131870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photodynamic treatment without verteporfin in chronic central serous chorioretinopathy.","authors":"Bilge Batu Oto, Oğuzhan Kılıçarslan, Seda Sert, Hüseyin Yetik","doi":"10.1186/s12886-025-04144-2","DOIUrl":"10.1186/s12886-025-04144-2","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to evaluate the clinical and optical coherence tomography (OCT) results of a newly proposed technique to treat chronic central serous chorioretinopathy (cCSR) and to determine its efficacy in cCSR treatment. This technique is termed photostatic treatment (PST).</p><p><strong>Study design: </strong>A prospective study which includes 44 eyes of 38 patients were treated with PST and followed up for at least 24 months.</p><p><strong>Methods: </strong>PST was performed by administering light energy delivered to the area using a 689 nm diode laser. PST was performed using the conventional fluence rate (60 J/cm²) with a conventional irradiation time of 83 s. Each patient was treated with 3 consecutive laser applications. The primary outcome measures were complete resolution of subretinal fluid and improvement in best-corrected visual acuity (BCVA).</p><p><strong>Results: </strong>The median central macular thickness (CMT) was significantly lower at the final visit after treatment than the initial presentation (median CMT 332,5µ versus 234µ, p < 0.001). Complete resolution of the fluid at the last visit could be achieved in 31 (70.4%) eyes with a significant improvement in median BCVA (p < 0.001).</p><p><strong>Conclusion: </strong>The application of laser treatment without a photosensitizing agent proved effective in controlling cCSR, and we propose the term 'photostatic treatment' for this new technique.</p>","PeriodicalId":9058,"journal":{"name":"BMC Ophthalmology","volume":"25 1","pages":"310"},"PeriodicalIF":1.7,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12100924/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144131866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for error in refractive astigmatism after toric intraocular lens implantation in Chinese patients.","authors":"Mengyao Zhang, Rui Qin, Yanfeng Liao, Qianqian Ji, Ying Hong","doi":"10.1186/s12886-025-04127-3","DOIUrl":"10.1186/s12886-025-04127-3","url":null,"abstract":"<p><strong>Background: </strong>To evaluate the risk factors for postoperative error in refractive astigmatism (ERA) in Chinese patients with cataract and astigmatism undergoing toric intraocular lens (IOL) implantation.</p><p><strong>Methods: </strong>Retrospective study. 132 patients who underwent cataract surgery with toric IOL implantation performed by a single surgeon at Peking University Third Hospital Department of Ophthalmology were enrolled. The Barrett Toric Calculator was used to calculate IOL power. Data collected included the patient's best-corrected visual acuity (BCVA), corneal curvature, central anterior chamber depth (ACD), axial length (AL), incision position, and IOL sphere and cylinder diopters. Corrected visual acuity, ERA, corneal curvature and ACD were collected 1 month after operation. All the participants were divided into two groups according to ERA(whether within 0.5 D or not).Logistic regression was performed to analyze the risk factors for postoperative ERA.</p><p><strong>Results: </strong>112 of the 132 patients (84.8%) had a < 0.5 D postoperative ERA. Logistic regression model showed that older age (OR = 1.102, 95% CI: 1.019-1.192), longer AL (OR = 1.611 95% CI: 1.069-2.429), and higher ΔACD (OR = 4.035, 95% CI: 1.086-15.00) were independent risk factors for postoperative ERA. However, gender, preoperative astigmatism, incision position were not independent risk factors for ERA.</p><p><strong>Conclusions: </strong>Factors contributing to ERA after toric IOL implantation include age, AL and ACD change before and after the surgery.</p>","PeriodicalId":9058,"journal":{"name":"BMC Ophthalmology","volume":"25 1","pages":"309"},"PeriodicalIF":1.7,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12100973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144131872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}