BMC Veterinary Research最新文献

{"title":"Factors affecting survival of foals with pneumonia in a referral hospital.","authors":"Heini Sofia Rossi, Heli Katariina Hyytiäinen, Jouni Juho Tapio Junnila, Minna Marjaana Rajamäki, Anna Kristina Mykkänen","doi":"10.1186/s12917-024-04405-0","DOIUrl":"10.1186/s12917-024-04405-0","url":null,"abstract":"<p><strong>Background: </strong>Pneumonia is a common condition in ailing neonatal foals, and it remains an important cause of morbidity and mortality in this veterinary patient group. Factors affecting the survival of young foals with pneumonia have not been thoroughly investigated. The aim of this study was to explore the potential prognostic factors associated with survival of these foals. Fifty foals under one month of age with pneumonia were included in this retrospective clinical study. The foals were divided into groups based on survival (survived to discharge or died/euthanised during hospitalisation). Multiple clinical and laboratory variables were investigated as risk factors with univariate logistic regression analyses and subsequently with multivariate analyses. If a variable showed prediction potential in regression analysis, a receiver operating characteristic (ROC) analysis was conducted.</p><p><strong>Results: </strong>In univariate analysis, odds (OR, 95% CI) of non-survival were associated with higher respiratory rate (RR) on the first day after admission to hospital (D1) (1.32, 1.07-1.62, P = 0.009, for each 5-unit increase) and positive bacterial blood culture (12.08, 1.88-77.67, P = 0.009). Odds of non-survival were decreased for Standardbred breed (0.11, 0.01-0.96, P = 0.046) and for foals with longer hospitalisation, with each additional day in hospital further reducing the odds (0.59, 0.40-0.86, P = 0.006). In multivariate analysis, odds of non-survival were associated only with higher RR on D1 (1.36, 1.07-1.71, P = 0.011, for each 5-unit increase). In ROC analysis, optimal cut-off value for RR was ≥ 55/min with sensitivity 75.0% and specificity 76.3%. Based on predictive values, RR < 55/min on D1 favoured survival.</p><p><strong>Conclusions: </strong>Higher RR on D1 is a predictor of non-survival in foals with pneumonia in this study, increasing the odds of death by 36% for each 5-unit increase in RR. Respiratory rate below 55/min on D1 favours survival. These findings could assist in early identification of foals that are at increased risk of mortality, thereby aiding in treatment decisions.</p>","PeriodicalId":9041,"journal":{"name":"BMC Veterinary Research","volume":"20 1","pages":"562"},"PeriodicalIF":2.3,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11653636/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142852533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin E nanoparticles enhance performance and immune status of Nile tilapia.","authors":"Enas A H Farag, Mohamed Z Baromh, Naglaa El-Kalamwi, Ahmed H Sherif","doi":"10.1186/s12917-024-04398-w","DOIUrl":"10.1186/s12917-024-04398-w","url":null,"abstract":"<p><p>Vitamin E (VE) is an essential vitamin liposoluble antioxidant in aquatic animals that is usually lost during feed processing and digestion, whereas nano-chitosan, a polysaccharide, could protect VE. In this study, Nile tilapia (70.85 ± 0.2 g) was fed VE (100 mg/kg dry diet) and a chitosan protected-VE nanoparticle (NPs) with gradual percentages of recommended dose 25%, 50%, 75%, and 100% for 4, 6, and 8 weeks. Growth parameters total weight gain (TG), daily weight gain (DWG), and relative growth rate (RGR) were significantly and positively correlated with VENPs additions. Regardless of the addition level, the feed conversion ratio (FCR) was significantly lower in the VENP groups. Lysozyme, serum antibacterial activity, and oxidative burst activity indicated the superiority of VENPs (VENPs75 and VENPs100) in enhancing the fish's innate immunity compared to bulk VE and the control groups. Fish were experimentally challenged with pathogenic Aeromonas hydrophila; those received dietary showed a low mortality rate (MR%), about 40% compared with 70% in the control with lower re-isolation compared to the control and VE groups. VENPs could provide ascending relative protection level during the period of 4 to 8 weeks; RPL ranged from 33.3 to 42.86% (VENPs100), 16.67-42.86% (VENPs75), 0 to 28.57% (VENPs50), and 0 to 14.29% (VENPs25 and VE), respectively. Finally, this study recommended incorporating VENPs into the Nile tilapia diet at 50, 75, and 100 mg/ kg fish feed. Fish in the VENPs75 and VENPs100 groups were immune boosted, becoming less vulnerable to A. hydrophila infection.</p>","PeriodicalId":9041,"journal":{"name":"BMC Veterinary Research","volume":"20 1","pages":"561"},"PeriodicalIF":2.3,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11636036/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful diagnosis and treatment of canine polymyositis: utilizing MRI and immunohistochemistry for accurate detection.","authors":"Jungwoo Han, KeunHwan Jang, Seung-Bum Cho, SuYeon Kim, Songju Oh, Ha-Jung Kim","doi":"10.1186/s12917-024-04356-6","DOIUrl":"10.1186/s12917-024-04356-6","url":null,"abstract":"<p><strong>Background: </strong>Inflammatory myopathy is generally categorized into generalized inflammatory myopathies (gIM), which affect muscles throughout the body, and focal inflammatory myopathies (fIM), which are localized to specific muscles or muscle groups. This report details a case of immune-mediated polymyositis in a dog, successfully diagnosed using MRI and IHC and managed with immunosuppressive therapy.</p><p><strong>Case presentation: </strong>A 5-year-old castrated male Poodle was admitted to our hospital presenting with lethargy and exercise intolerance. Biochemical analysis revealed significantly elevated serum levels of aspartate aminotransferase (AST) and creatine kinase (CK). Physical examination showed muscle atrophy in the hind legs, but further orthopedic and neurological examinations identified no additional abnormalities. MRI demonstrated hyperintense and heterogeneous signal changes across the muscles, including contrast enhancement, suggesting inflammatory myopathy. This diagnosis was confirmed through histopathological examination, which revealed inflammatory lesions with fibrous tissue proliferation within the muscle tissue. To investigate the presence and type of inflammatory cells and vascular changes, aiding in the differential diagnosis of inflammatory myopathies, immunohistochemistry (IHC) was performed, revealing positive findings for CD8⁺, CD4⁺, and VEGF in the evaluated tissue, leading to a diagnosis of polymyositis.</p><p><strong>Conclusions: </strong>The dog was diagnosed with immune-mediated polymyositis and treatment was initiated with prednisolone at 1 mg/kg twice daily and azathioprine at 2 mg/kg once daily. Following the administration of these immunosuppressive agents, CK levels returned to normal, and the dog's exercise intolerance and lethargy resolved. The thickness of the hind legs also increased progressively. The dog has maintained an improved condition under continued immunosuppressive therapy for four months. This case highlights the critical role of MRI and immunohistochemistry in diagnosing immune-mediated polymyositis, demonstrating their alternative capability in cases where conventional electromyography (EMG) is not feasible in this context.</p>","PeriodicalId":9041,"journal":{"name":"BMC Veterinary Research","volume":"20 1","pages":"560"},"PeriodicalIF":2.3,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11629501/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142806238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The first serological survey of C. Burnetii in domestic animals in Poland.","authors":"Hanna Turlewicz-Podbielska, Jakub Jędrzej Ruszkowski, Małgorzata Pomorska-Mól","doi":"10.1186/s12917-024-04423-y","DOIUrl":"10.1186/s12917-024-04423-y","url":null,"abstract":"<p><strong>Background: </strong>• Q fever, known as coxiellosis in animals, represents a global zoonotic threat caused by the intracellular bacterium Coxiella burnetii (C. burnetii). The disease affects many animal species, including those considered significant reservoirs, such as cattle, sheep and goats. Transmission of the pathogen to other domestic animals, including companion animals, and then to humans has also been observed, highlighting the importance of understanding the epidemiology and prevalence of C. burnetii among companion animals. The present study aimed to determine the frequency of seroreagents for C. burnetii within pet dogs, cats and rabbits from urban Poland areas and identify possible risk factors for these animals.</p><p><strong>Results: </strong>• In total, serum samples from 491 dogs, 427 cats and 93 rabbits were used in the study. The seroprevalence of anti-C. burnetii antibodies in dogs and cats reached 0.61% (3/491; 95% CI: 0.21-1.78) and 0.23% (1/427; 95% CI: 0.04-1.31), respectively. No significant differences in seroprevalence across species and different subpopulations (age group, gender, exhibited symptoms, or sampling location) were found. All 93 samples from rabbits were negative for anti-C.burnetii antibodies.</p><p><strong>Conclusions: </strong>• The seroprevalence rates of C. burnetii in dogs and cats were low; however, our results confirm that pet dogs and cats in Poland can be exposed to C. burnetii and may exhibit serological reactions. It has been reported that people who come into contact with secretions and excretions from the reproductive systems of dogs and cats (such as breeders, veterinarians, and veterinary clinic staff) may be at risk of contracting C. burnetii. Based on the findings, it is advised to be particularly cautious, especially when assisting with dogs and cats giving birth. Coxiellosis should be considered a potential cause of reproductive disorders in these animals. The results indicate that rabbits are probably less important in the circulation of the C. burnetii in the present study. This is the first serological survey of C. burnetii in pet dogs, cats and rabbits in Poland.</p>","PeriodicalId":9041,"journal":{"name":"BMC Veterinary Research","volume":"20 1","pages":"559"},"PeriodicalIF":2.3,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11624599/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Construction of a camelid VHH yeast two-hybrid library and the selection of VHH against haemagglutinin-neuraminidase protein of the Newcastle disease virus.","authors":"Xiaolong Gao, Xiangyun Hu, Lina Tong, Dandan Liu, Xudong Chang, Haixin Wang, Ruyi Dang, Xinglong Wang, Sa Xiao, Enqi Du, Zengqi Yang","doi":"10.1186/s12917-024-04426-9","DOIUrl":"10.1186/s12917-024-04426-9","url":null,"abstract":"","PeriodicalId":9041,"journal":{"name":"BMC Veterinary Research","volume":"20 1","pages":"558"},"PeriodicalIF":2.3,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11624590/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wide spectrum of tick-borne pathogens in juvenile Ixodes ricinus collected from autumn-migrating birds in the Vistula River Valley, Poland.","authors":"Joanna Kulisz, Zbigniew Zając, Angelique Foucault-Simonin, Aneta Woźniak, Maciej Filipiuk, Janusz Kloskowski, Robert Rudolf, Alexandra Corduneanu, Katarzyna Bartosik, Sara Moutailler, Alejandro Cabezas-Cruz","doi":"10.1186/s12917-024-04415-y","DOIUrl":"10.1186/s12917-024-04415-y","url":null,"abstract":"<p><strong>Background: </strong>Migratory birds serve as potential hosts for ticks and can be reservoirs of tick-borne pathogens (TBPs). The aim of our study was to investigate the prevalence of TBPs in juvenile Ixodes ricinus collected from Erithacus rubecula, Turdus merula, and Turdus philomelos passing through the Vistula River Valley, Poland - one of the most important European north-south routes for migratory birds.</p><p><strong>Methods: </strong>To detect TBPs in collected ticks we used a high-throughput microfluidic real-time PCR method. In addition, we performed a phylogenetic analysis of Borreliella garinii flaB and Rickettsia helvetica ompB sequences, considering haplotype diversity through a Median Joining Network.</p><p><strong>Results: </strong>Our results showed a high prevalence and wide spectrum of TBPs in both larvae and nymphs of I. ricinus. Overall, including co-infections, 47.41% of the tested tick specimens were infected with at least one TBP. Borreliaceae spirochetes were detected in ticks collected from all examined bird species. Ticks (larvae and nymphs) collected from T. merula showed the highest prevalence of Bo. garinii (33.33%), Bo. burgdorferi s.s. (7.69%) and Borrelia miyamotoi (2.56%), while the highest number of ticks infected with Bo. valaisiana were collected from T. philomelos (8.11%). In turn, the highest prevalence of R. helvetica (20.00%) was observed in ticks collected from E. rubecula. Additionally, infections with A. phagocytophilum (5.00%), Ehrlichia spp. (2.50%), Ba. divergens (2.50%) and Ba. venatorum (2.50%) were only confirmed in ticks collected from this bird species. The phylogenetic analysis of Bo. garinii revealed that the detected haplotype circulates widely across various hosts and is geographically widespread, while the haplotype of R. helvetica is mainly detected in ticks in Central Europe.</p><p><strong>Conclusions: </strong>Ticks carried by T. merula, T. philomelos, and E. rubecula migrating along the Vistula River Valley, Poland are characterized by a high prevalence and a wide spectrum of detected TBPs. Tested ticks carry widespread strains of Bo. garinii, in contrast to R. helvetica, which is mainly found in Central Europe. Therefore, further research on the possible role of birds as reservoirs of TBPs is needed.</p>","PeriodicalId":9041,"journal":{"name":"BMC Veterinary Research","volume":"20 1","pages":"556"},"PeriodicalIF":2.3,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622654/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supplementation of laying hens' feed with Schizochytrium powder and its effect on physical and chemical properties of eggs.","authors":"Ifra Kiran, Huma Umbreen, Mahr Un Nisa, Fahad Al-Asmari, Eliasse Zongo","doi":"10.1186/s12917-024-04424-x","DOIUrl":"10.1186/s12917-024-04424-x","url":null,"abstract":"<p><p>Biofortification enhances dietary quality and nutritional value using traditional marine microalga species, particularly docosahexaenoic acid (DHA), which is an essential n-3 fatty acid for human health. Eggs are natural fortified candidates. This study aimed to investigate the effect of dietary Schizochytrium powder on egg productivity, egg nutritional content, and fatty acid levels in laying hens. Hy-Line Brown laying hens (n = 150) were uniformly assigned to five groups for 52 days. The control group received no supplements, whereas the other four experimental groups were provided with varied amounts of schizochytrium powder. The experimental feed contained isonitrogenous (16.60%) and isocaloric metabolizable energy, 36.69 MJ/kg components. No significant differences were observed (p > 0.05) on different parameters such as average daily feed intake, feed conversion ratio, egg weight, and shell thickness. Enriching eggs significantly increased α-linolenic acid (ALA), eicosapentaenoic acid (EPA), and DHA levels (p < 0.001), while decreasing the n-6/-3 ratio in a dose-dependent manner, ensuring high quality and biological efficacy. A plateau point was maintained throughout the study period. In the first two weeks, increased DHA levels were observed in egg yolks when microalgae concentrations were elevated by 1%. The study found that powdered Schizochytrium limacinum served as a substitute for DHA in enhancing eggs with n-3 fatty acids.</p>","PeriodicalId":9041,"journal":{"name":"BMC Veterinary Research","volume":"20 1","pages":"557"},"PeriodicalIF":2.3,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622691/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Herd and animal level seroprevalence and associated risk factors of Leptospira interrogans sensu lato serovar Hardjo in cattle in southwest Ethiopia.","authors":"Dereje Tulu Robi, Ararsa Bogale, Melkam Aleme, Beksisa Urge","doi":"10.1186/s12917-024-04418-9","DOIUrl":"10.1186/s12917-024-04418-9","url":null,"abstract":"<p><p>Leptospirosis is a significant zoonotic disease that causes high economic losses in cattle production due to its association with abortions, stillbirths, infertility, and reduced milk yields. However, the epidemiology of bovine leptospirosis in Ethiopia is poorly understood. From October 2020 to October 2021, a cross-sectional study was conducted to investigate the seroprevalence of serovar Hardjo in cattle in southwest Ethiopia, as well as the associated risk factors. To test for the existence of L. Hardjo antibodies, blood samples were taken from 461 cattle. Indirect ELISA was used to identify the presence of antibodies against L. Hardjo in sera samples. We conducted a multivariable random-effect logistic regression analysis to identify potential risk factors associated with L. Hardjo seropositivity. An overall L. Hardjo seroprevalence of 24.7% (95% CI: 20.2-48.8) and 53.5% (95% CI: 45.7-90.5) was recorded at the animal level and the herd level, respectively, in the study areas. This study revealed six factors influencing L. Hardjo seropositivity in cattle herds. Large herds had twice the odds of seropositivity (OR = 2.0, 95% CI: 1.1-3.8) compared to small herds. Co-grazing cattle exhibited higher odds (OR = 2.2, 95% CI: 1.2-4.1) of seropositivity. Extensive management systems significantly increased the odds (OR = 10.3, 95% CI: 1.7-61.8) compared to semi-intensive systems. Highland cattle had higher odds (OR = 3.7, 95% CI: 1.4-10.3) than lowland cattle. Older cattle (OR = 4.6, 95% CI: 2.4-8.9) were more likely to be seropositive. At the herd level, extensive management (OR = 2.8, 95% CI: 1.3-5.8) and large herds (OR = 2.5, 95% CI: 1.3-4.7) increased the risk of seropositivity. Herds with sheep/goats (OR = 2.3, 95% CI: 1.3-4.1) were also at higher risk, highlighting significant L. Hardjo seropositivity risk factors in cattle herds. The study findings showed that leptospirosis was highly prevalent across the study areas. As a result, use proper management, raise zoonotic awareness for leptospirosis, and conduct molecular bovine leptospirosis research in study areas were recommended.</p>","PeriodicalId":9041,"journal":{"name":"BMC Veterinary Research","volume":"20 1","pages":"553"},"PeriodicalIF":2.3,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622666/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142784015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rosmarinic acid-mediated downregulation of RIG-I and p62 in microglia confers resistance to Japanese encephalitis virus-induced inflammation.","authors":"Yuxin Yang, XianWang Hu, Shuangshuang Wang, Yongxiang Tian, Keli Yang, Chang Li, Qiong Wu, Wei Liu, Ting Gao, Fangyan Yuan, Rui Guo, Zewen Liu, Yuying Yang, Danna Zhou","doi":"10.1186/s12917-024-04397-x","DOIUrl":"10.1186/s12917-024-04397-x","url":null,"abstract":"<p><strong>Background: </strong>Japanese encephalitis virus (JEV) is a mosquito-borne zoonotic pathogen that causes encephalitis in humans and reproductive failure in pigs. The transmission of JEV between humans and animals poses a significant public health threat and results in substantial economic losses. Excessive inflammation in the central nervous system of JEV-infected patients is a major cause of mortality and disability. Rosmarinic acid (RA), a polyhydroxyphenolic compound isolated from medicinal herbs, has been preliminarily shown to possess anti-inflammatory properties and significantly inhibit JEV-induced neuroinflammation in mice.</p><p><strong>Results: </strong>This study investigated the antiviral capacity and potential mechanisms of RA in JEV-infected cells. The results demonstrated that RA could inhibit JEV replication in vitro. Furthermore, the expression levels of inflammatory cytokines (including IL-6, IL-1β, CCL-2, and TNF-α), membrane receptors (including RIG-I, TLR3, TLR4, TLR7, and TLR8), NF-κB complex and p62/SQSTM1 were assessed using qPCR, ELISA, and Western blot, respectively. The findings indicated that RA significantly suppressed the expression of IL-6, IL-1α, TNF-α, and CCL-2 in JEV-infected BV-2 cells in a dose-dependent manner. Additionally, RA treatment downregulated the expression levels of RIG-I and p62, while p62 silencing inhibited the upregulation of inflammatory cytokines in JEV-infected BV-2 cells.</p><p><strong>Conclusion: </strong>Our present study highlights the important role of RA-mediated reduction of RIG-I and p62 in microglia, conferring resistance to Japanese encephalitis virus-induced inflammation.</p>","PeriodicalId":9041,"journal":{"name":"BMC Veterinary Research","volume":"20 1","pages":"555"},"PeriodicalIF":2.3,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622684/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of porcine respiratory disease complex on carcass weight and meatiness: quantitative insights from a mixed-model analysis.","authors":"Paulina Przyborowska, Renata Lewko-Wojtowicz, Piotr Cybulski, Dominiek Maes, Dawid Tobolski","doi":"10.1186/s12917-024-04410-3","DOIUrl":"10.1186/s12917-024-04410-3","url":null,"abstract":"<p><strong>Background: </strong>Porcine respiratory disease complex (PRDC) significantly impacts the swine industry worldwide, leading to economic losses due to poor growth performance, reduced feed efficiency, higher medication costs, and adversely affecting pig welfare by causing clinical symptoms such as fever, cough, loss of appetite, lethargy, and dyspnea. Cranio-ventral pulmonary consolidation (CVPC) and pleuritis are the most frequent macroscopic lung lesions observed in PRDC and are indicators of decreased animal welfare. This study aimed to quantify the effects of CVPC and pleurisy on carcass weight, meatiness, and average daily carcass weight gain (ADCWG) in fattening pigs, thereby assessing their impact on both production and welfare. A total of 679 slaughtered pigs from seven batches (farms) were evaluated for lung lesions at slaughter. We employed a mixed-model analysis to assess the correlation between lung lesions and production parameters across the farms.</p><p><strong>Results: </strong>The mean prevalence of lesions was 23.86% for CVPC and 15.46% for pleurisy, indicating a significant presence of respiratory disease affecting animal welfare. Pigs with severe lung lesions (≥ 15.1%) exhibited significantly lower ADCWG compared to pigs without lesions (0.951 kg/day vs. 0.997 kg/day, p = 0.024), reflecting reduced growth performance and welfare. The mixed-effects model revealed that lesions in the right apical lobe and dorso-caudal pleurisy were associated with significant reductions in carcass weight (- 2.77 kg and - 2.29 kg, respectively) and carcass meat (- 1.76 kg and - 1.43 kg, respectively). An economic analysis under average market price conditions demonstrated that severe lung lesions could lead to financial losses of up to 11.53 EUR per 100 kg of meat, emphasizing the economic impact of compromised welfare due to respiratory diseases.</p><p><strong>Conclusions: </strong>This study provides quantitative evidence of the negative impact of CVPC and pleurisy on carcass weight and meatiness in fattening pigs. The findings underscore the importance of effective respiratory disease management in swine production, highlighting potential areas for targeted interventions to improve animal health and economic outcomes.</p>","PeriodicalId":9041,"journal":{"name":"BMC Veterinary Research","volume":"20 1","pages":"554"},"PeriodicalIF":2.3,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622469/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}