BMC Psychiatry最新文献

{"title":"Global trends of depressive disorders among women of reproductive age from 1990 to 2021: a systematic analysis of burden, sociodemographic disparities, and health workforce correlations.","authors":"Fangyi Dai, Yuzhou Cai, Min Chen, Yong Dai","doi":"10.1186/s12888-025-06697-4","DOIUrl":"10.1186/s12888-025-06697-4","url":null,"abstract":"<p><strong>Background: </strong>Depressive disorders significantly impact women of reproductive age (15-49 years), who face unique biological and social pressures-such as hormonal changes and caregiving responsibilities-that elevate their mental health risks. Despite rising prevalence, regional disparities in burden remain poorly understood. Moreover, no studies to date have examined the relationship between depressive disorders in women of reproductive age and different categories of health workforce. This study examines global, regional, and national trends from 1990 to 2021, highlighting socio-demographic disparities and exploring correlations with health workforce distribution.</p><p><strong>Methods: </strong>Using data from the Global Burden of Disease Study, we examined the prevalence, incidence, and disability-adjusted life years (DALYs) of depression in women of childbearing age (15-49 years) across 204 countries and territories from 1990 to 2021. Long-term trends were assessed through estimated annual percentage change (EAPC), while decomposition analyses identified drivers of disease burden changes. We also analyzed correlations between depressive disorder burden and various health workforce categories using data from the GBD 2019 Health Workforce Collaborators.</p><p><strong>Results: </strong>From 1990 to 2021, the global prevalence of depression in women of reproductive age rose by 67.58%, incidence by 71.44%, and DALYs by 69.08%. Notably, this burden increased dramatically during the COVID-19 pandemic, with prevalence rising by 17.86%, incidence by 24.51%, and DALYs by 20.80% between 2019-2021 alone. Regions with low sociodemographic index (SDI) saw the largest increase in absolute cases (157.80% for prevalence), while high SDI regions experienced the fastest rise in age-standardized rates (32.45% for prevalence). Among all SDI levels, the 15-19 age group exhibited the greatest increase. Decomposition analyses indicated that population growth primarily drove the increased disease burden, though epidemiological changes played a larger role in high SDI regions. Our analysis revealed significant correlations between depressive disorder burden and health workforce distribution. Notably, countries with high depressive disorder burden, such as Georgia, might benefit from increasing the number of Audiologists and Counsellors while optimizing the role of Medical Assistants and Community Health Workers in detection and referral.</p><p><strong>Conclusion: </strong>The global burden of depression among women of childbearing age is increasing significantly, with a marked acceleration during the COVID-19 pandemic period. Notable disparities exist across regions and age groups, with differential impacts in pre-pandemic versus pandemic timeframes. The correlations between health workforce categories and depressive disorder burden underscore the need for targeted interventions and resource allocation. These findings highlight the urgent need for str","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"263"},"PeriodicalIF":3.4,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924784/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143668814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Causal relationships between schizophrenia and psoriasis: a two-sample Mendelian randomization study.","authors":"Lusheng Miao, Taosheng Miao, Ying Zhang, Jin Hao","doi":"10.1186/s12888-025-06687-6","DOIUrl":"10.1186/s12888-025-06687-6","url":null,"abstract":"<p><strong>Background: </strong>Numerous clinical studies have investigated the association between schizophrenia and psoriasis, but the findings remain inconsistent.</p><p><strong>Methods: </strong>We employed Mendelian randomization (MR) methods to evaluate the causal relationship between schizophrenia and psoriasis and its subtypes. Inverse variance weighting was used as the primary approach for MR analysis, complemented by inverse magnetic resonance analysis and sensitivity testing. To identify potential mediators, we applied a two-step MR approach. Additionally, pathway and functional enrichment analyses were conducted to uncover possible mechanisms linking schizophrenia and psoriasis.</p><p><strong>Results: </strong>MR analysis indicated an association between schizophrenia and psoriasis (OR: 1.0010; p = 0.008). Subtype analyses revealed that genetic susceptibility increased the risk of developing psoriasis vulgaris (OR: 1.18; 95% CI: 1.03-1.34; p = 0.016) but was not significantly associated with arthropathy (OR: 1.04; 95% CI: 0.97-1.12; p = 0.292). Emotional states such as tenseness, tiredness, and misery fulfil the criteria of the MR two-step approach and can be considered as potential mediators of the association between schizophrenia and psoriasis vulgaris. Pathway and functional enrichment analyses suggested the involvement of oxidative stress-driven hypothalamic-pituitary-adrenal (HPA) axis pathways in the link between schizophrenia and psoriasis.</p><p><strong>Conclusion: </strong>Our MR study established a significant association between schizophrenia and psoriasis vulgaris, identifying tenseness, tiredness, and misery as potential mediators. Pathway and functional enrichment analyses indicated that oxidative stress in the HPA axis may represent a shared mechanism underlying schizophrenia and psoriasis.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"264"},"PeriodicalIF":3.4,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143668840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric properties of Japanese version of the Recovering Quality of Life (ReQoL).","authors":"Ayako Hada, Takayuki Kawaguchi, Kaori Usui, Mai Iwanaga, Sayaka Sato, Sosei Yamaguchi, Naoaki Kuroda, Chiyo Fujii","doi":"10.1186/s12888-025-06622-9","DOIUrl":"10.1186/s12888-025-06622-9","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to examine the psychometric properties of the Recovering Quality of Life- Japanese version (ReQoL-J) for use in the community setting.</p><p><strong>Methods: </strong>This cross-sectional study was conducted among service users of community mental health service facilities. A series of confirmatory factor analyses (CFAs) was performed. After the best-fitting model was identified, omega indices, and intraclass correlation (ICC) were calculated to evaluate dimensionality and reliability. The correlation coefficients between the ReQoL-J scores and the other scales were calculated for testing construct validity. We also estimated the correlation coefficients between the ReQoL-J-10 and - 20.</p><p><strong>Results: </strong>A total of 395 service users from 23 facilities in Japan participated in this study. Of these, 66 responded to the test-retest reliability. The bifactor model showed the best fit to the data: χ²/df = 1.74, CFI = 0.993, RMSEA = 0.031, and SRMR = 0.038. ECV and OmegaH indicated unidimensionality. ICC for the Re-QoL-J-10 and - 20 were 0.700 and 0.766, respectively. The ReQoL-J-10 showed a high correlation with the ReQoL-J-20 (r =.95, p <.001). The EQ-5D-5 L, a new brief scale for subjective personal agency (SPA-5), well-being and the quality of life scale (QLS) scores were positively correlated with the ReQoL-J score. On the other hand, the patient health questionnaire-9 (PHQ-9) and the WHODAS scores were negatively correlated with the ReQoL-J score.</p><p><strong>Conclusion: </strong>Factor structure, internal consistency, test-retest reliability, and construct validity of the ReQoL-J were confirmed. The ReQoL-J is a promising tool as a patient-reported outcome measure in mental health services for the Japanese community setting.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"265"},"PeriodicalIF":3.4,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11927262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143668779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of oxidative stress and GDNF on patients with bipolar disorder: a prospective study.","authors":"Qun Yang, Chuanwei Li, Fei Jiang, Jiancheng Qiu, Haidong Yang, Qing Tian, Xiaobin Zhang","doi":"10.1186/s12888-025-06698-3","DOIUrl":"10.1186/s12888-025-06698-3","url":null,"abstract":"<p><strong>Background: </strong>Bipolar disorder (BD) is a common mental disorder characterized by significant cognitive dysfunction, the mechanisms of which remain unclear. Oxidative stress and glial cell line-derived neurotrophic factor (GDNF) influence the pathophysiology of BD. Their specific roles, particularly concerning cognitive function during manic episodes, are unclear. The serum levels of superoxide dismutase (SOD) and malondialdehyde (MDA), and GDNF were biochemically assayed in patients with bipolar mania before and after treatment to explore their associations with cognitive function.</p><p><strong>Methods: </strong>A total of 75 patients in acute manic episodes of BD and 70 healthy controls were initially enrolled. During the 4-week intervention period with atypical antipsychotics and mood stabilizers, 5 patients discontinued follow-up, resulting in 70 completers included in the final analysis. The severity of manic symptoms were assessed using the Young Mania Rating Scale (YMRS). Cognitive function was assessed by the Digit Cancellation, Stroop Color and Word, and Trail Making Tests. Serum levels of SOD, MDA, and GDNF were measured using biochemical assays.</p><p><strong>Results: </strong>BD patients demonstrated higher serum SOD and MDA levels and lower GDNF levels compared to controls, following improvements after treatment. Pre-treatment YMRS scores and cognitive function assessments positively correlated with SOD and MDA levels, and negatively correlated with GDNF levels. Treatment significantly improved manic symptoms and cognitive function, although GDNF levels remained lower than in controls.</p><p><strong>Conclusions: </strong>The demonstrated associations with symptoms and cognitive functions during the manic phase substantially advance the understanding of the role of oxidative stress and GDNF in BD. Possible biomarkers for BD diagnosis and prognosis assessment are revealed. Further investigations into the complex pathophysiological mechanisms of BD are needed.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"258"},"PeriodicalIF":3.4,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11921738/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring generalized anxiety disorder symptoms: key insights from a population-based study in Iran.","authors":"Fardin Alipour, Hassan Rafiey, Sahar Sarmadi, Narges DostKaramooz, Mostafa Mardani, Golafrooz Gholamy, Mehdi Noroozi","doi":"10.1186/s12888-025-06707-5","DOIUrl":"10.1186/s12888-025-06707-5","url":null,"abstract":"<p><strong>Aim: </strong>Generalized Anxiety Disorder (GAD) is a common mental health condition with considerable impacts on both individuals and society, associated with high healthcare costs and reduced quality of life. Linked to a range of genetic, psychological, and social factors, GAD also frequently coexists with other mental health conditions. This study investigates the socio-demographic, environmental, and psychosocial risk factors for GAD symptoms in an urban Iranian population, addressing a key research gap and guiding targeted interventions.</p><p><strong>Method: </strong>A cross-sectional study was conducted to determine the prevalence and associated factors of GAD symptoms among adults in Tehran. Using multi-stage sampling, participants completed questionnaires on socio-demographic characteristics, recent stressors, and DSM-5 criteria for GAD. Descriptive statistics identified prevalence patterns, and logistic regression models evaluated associations and adjusted for confounders (p < 0.05). Analyses were conducted in STATA v.14, with adjusted odds ratios and 95% confidence intervals reported.</p><p><strong>Results: </strong>Of 970 participants, 26% met criteria for GAD (CI 95%: 22%-32%). Individuals with GAD were more likely to be single, dissatisfied with life, of low socioeconomic status, and to report non-healthy status and recent stressors. In multivariable regression, significant risk factors for GAD included female gender (AOR = 1.4, p < 0.01), experiencing at least one recent stressful event (AOR = 1.9, p = 0.01), and poor health status (AOR = 2.8, p < 0.05).</p><p><strong>Conclusion: </strong>This study highlights the prevalence of GAD symptoms in Tehran and underscores the critical roles of policymakers and healthcare providers in addressing it. Effective management requires a multifaceted approach, including individual treatment, social integration, and community support. Future research should focus on culturally sensitive interventions and awareness campaigns to reduce stigma. Overall, the study enriches the literature on GAD in Iran and encourages collaborative efforts to enhance mental health outcomes and community well-being.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"262"},"PeriodicalIF":3.4,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924773/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining the research methods of early warning signals in clinical psychology through a theoretical lens.","authors":"Jingmeng Cui, Merlijn Olthof, Fred Hasselman, Anna Lichtwarck-Aschoff","doi":"10.1186/s12888-025-06688-5","DOIUrl":"10.1186/s12888-025-06688-5","url":null,"abstract":"<p><strong>Background: </strong>The past few years have seen a rapid growth in research on early warning signals (EWSs) in the psychopathology domain. Whereas early studies found EWSs to be associated with sudden changes in clinical change trajectories, later findings showed that EWSs may not be general across variables and cases and have low predictive power. These mixed results may be explained by the diverse methods employed in clinical EWS studies, with some of these approaches and practices potentially misaligned with the underlying theory of EWSs.</p><p><strong>Methods: </strong>This article employs a variety of methods, such as a narrative review, mathematical derivations, simulations, and visual illustrations, to support our claims, explain specific assumptions, and guide future empirical research. This multitude of methods serves our aim to provide theoretical as well as methodological contributions to the field.</p><p><strong>Results: </strong>We identify the following key assumptions for EWS validation studies: the system departs from a point attractor, EWSs appear before the critical transition, and EWS variables align with system destabilization. The literature review shows that the common research practices in the field are often not in line with those assumptions, and we provide specific suggestions corresponding to each of the assumptions.</p><p><strong>Conclusions: </strong>More rigorous empirical evidence is needed to better validate the existence of EWSs in clinical sudden changes and fully realize their clinical potential. As theory-based prediction tools, EWSs require stronger alignment between theory and practice to enhance both theoretical understanding and predictive accuracy.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"261"},"PeriodicalIF":3.4,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924765/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of metacognition and social cognition in childhood trauma effecting on prognosis: 1-year follow-up study in patients with first-episode schizophrenia.","authors":"Özge Selin Özen Sekmek, Gülsüm Zuhal Kamış, Bedirhan Şenol, Özgecan Özgün Erol, Mustafa Uğurlu, Erol Göka","doi":"10.1186/s12888-025-06686-7","DOIUrl":"10.1186/s12888-025-06686-7","url":null,"abstract":"<p><strong>Background: </strong>Childhood trauma (CT) is common in first episode schizophrenia (FES), affecting prognosis and functionality. However, the mechanisms by which CT effects prognosis are not clear. This study aimed to investigate how metacognition (MC) and social cognition (SC) mediate effects of CT on symptoms in FEP.</p><p><strong>Methods: </strong>52 first episode schizophrenia patients who were diagnosed for first time and had been symptomatic for at most 2 years were included. Patients were administered Metacognition Assessment Scale-Abbreviated to assess MC; Reading the Mind in the Eyes Test, Facial Emotion Recognition and Discrimination Tests to assess SC; Positive and Negative Syndrome Scale to assess psychopathology and Global Assessment of Functioning Scale to assess functionality at first interview. Patients were followed up for 1 year. At second interview the above scales and Childhood Trauma Questionnaire-33 were applied to 38 patients who met remission criteria.</p><p><strong>Results: </strong>MC and SC modulated effects of CT on negative symptoms, but not on positive symptoms. CT had different effects on symptoms, MC and SC skills in episode and remission. Pharmacological treatment was not sufficient to improve these skills.</p><p><strong>Conclusions: </strong>MC and SC skills are important in modulating CT effecting on prognosis and non-pharmacological interventions should be developed to improve these skills.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"260"},"PeriodicalIF":3.4,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11921519/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measuring functioning among youth using the Columbia impairment scale: investigating dimensionality and measurement invariance among 14-17 year olds using mental health services and their caregivers.","authors":"Kristin Cleverley, Sarah Brennenstuhl, Peter Szatmari, Lisa D Hawke, Karolin R Krause, Amy Cheung, Jacqueline Relihan, Mahalia Dixon, Jo Henderson","doi":"10.1186/s12888-025-06511-1","DOIUrl":"10.1186/s12888-025-06511-1","url":null,"abstract":"<p><strong>Background: </strong>Despite being a widely used and recommended measure of functioning, the Columbia Impairment Scale (CIS) lacks consensus on scale structure and whether child- and parent-report versions measure the same construct(s). This study aimed to better understand the structure and test for measurement invariance across groups of youth and their caregivers.</p><p><strong>Methods: </strong>The sample included youth 14-17 years of age accessing mental health services, and their caregiver (most often mother), recruited from one of five mental health outpatient hospital sites in Toronto, Canada between September 2016 and March 2020. Exploratory Structural Equation Modeling (ESEM) was used to investigate dimensionality and test for measurement invariance using standard model fit statistics.</p><p><strong>Results: </strong>A total of 189 youth-caregiver dyads were included in the analysis. Youth were on average aged 15.7 (sd = 1.1); 64% were female. Caregivers had a mean age of 48.2 (sd = 7.4) and were 87% mothers. Using ESEM, evidence of a three-factor model was found (\"work/school\", \"home/family\" and \"socializing\"), which included several, large conceptually relevant cross-loadings. Using this model, full metric invariance between youth and caregivers was established, but strong evidence of scalar invariance was not found.</p><p><strong>Conclusions: </strong>While a multi-dimensional model provided the best fit for the CIS, the presence of several large cross-loadings calls into question whether and how the global scale can best be used in clinical and research settings. Lack of evidence of scalar invariance suggests that multi-informant data should be interpreted carefully. Next steps should include testing for essential unidimensionality.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"259"},"PeriodicalIF":3.4,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11921662/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A survey of patient-physician communication regarding treatment prospects and goal setting in the management of major depressive disorder in Japan.","authors":"Takashi Tsuboi, Takeo Nakayama, Junko Horie, Fumie Tokuda, Yoshiya Moriguchi, Tatsuya Hoshino","doi":"10.1186/s12888-025-06606-9","DOIUrl":"10.1186/s12888-025-06606-9","url":null,"abstract":"<p><strong>Background: </strong>Major depressive disorder (MDD) is a common and debilitating cause of disability worldwide. Recently, it has been suggested that individualized goal setting may play a role in patient-centered recovery. This study aimed to survey the landscape of patient-physician communication around goal setting for MDD treatment, as well as understand whether goal setting using the SMART (specific, measurable, attainable, realistic, and time-bound) framework is associated with positive treatment indicators in MDD.</p><p><strong>Methods: </strong>Patients in Japan (≥ 18 years of age) who self-reported a verified MDD diagnosis were eligible to complete a self-administered survey through the Personal Health Record service, a web-based smartphone app. Patients were asked about whether they communicated with physicians about treatment prospects and/or goals. A 'SMART-Goal score' tool was developed to evaluate patient goals against the five SMART criteria. Treatment satisfaction scores and scores on the Wake Forest Physician Trust Scale Short Version (TRUST) were assessed as indicators of outcomes in this study. Descriptive questions were used to explore patients' perceptions of goal setting.</p><p><strong>Results: </strong>In total, 466 patients were eligible for inclusion in the analysis. The majority (70.0%) reported communicating with their physicians about treatment prospects and/or goals. These patients (Com + group) had a median (Q1, Q3) TRUST score of 70.0 (60.0, 80.0), compared with 50.0 (40.0, 70.0) in patients who reported an absence of communication (Com - group). Median (Q1, Q3) treatment satisfaction scores were 5.0 (4.0, 6.0) and 4.0 (3.0, 5.0) for the Com + and Com - groups, respectively. In high SMART-Goal scoring groups, approximately 75% of patients exceeded the overall median scores for TRUST (70.0) or treatment satisfaction (5.0) reported for the Com + group; only 25% of patients in low SMART-Goal scoring groups achieved the same in either measure. Most patients (89.3%) who set goals recommended goal setting.</p><p><strong>Conclusions: </strong>This exploratory study suggests that communication between patients and physicians regarding goal setting in MDD treatment may be associated with positive patient perceptions of treatment. High-quality SMART goal setting also appears to have positive aspects for patients with MDD, which may in turn affect treatment outcomes. Further studies are needed to confirm these initial findings.</p><p><strong>Trial registration: </strong>Registered on the UMIN Clinical Trials Registry (ID: UMIN000050370) on 17 February 2023.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"255"},"PeriodicalIF":3.4,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11921671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of night shifts on the physical and mental health of psychiatric medical staff: the influence of occupational burnout.","authors":"Chien-Chih Chen, Lieh-Yung Ping, Yu-Li Lan, Chih-Yu Huang","doi":"10.1186/s12888-025-06701-x","DOIUrl":"10.1186/s12888-025-06701-x","url":null,"abstract":"<p><strong>Background: </strong>The mental health of mental health care professionals has become a key area of research due to the increasing demands and stressors inherent in the work environment. This study explored the relationship between night shift work stress, burnout, social support, and physical and mental health among psychiatric medical staff.</p><p><strong>Methods: </strong>A cross-sectional survey was conducted among 244 psychiatric medical staff at a psychiatric specialty hospital in eastern Taiwan. The study utilized validated instruments, including the Effort-Reward Imbalance Questionnaire, the Maslach Burnout Inventory, the Social Support Scale, and the SF-12 Health Survey, to measure work stress, burnout, social support, and health outcomes. Descriptive statistics, Pearson correlation, and hierarchical regression analyses were employed to assess the relationships among these variables and the moderating effects of social support.</p><p><strong>Results: </strong>The findings revealed significant positive correlations between work stress and occupational burnout (r = 0.42, p < 0.001) and negative correlations with physical and mental health (r = - 0.23, p < 0.001). Occupational burnout is a negative significant predictor of physical and mental health (β = -0.533, p < 0.001). Additionally, higher levels of social support were associated with better health outcomes (r = 0.18, p < 0.01), although its moderating effect on the relationship between stress and health was not significant.</p><p><strong>Conclusion: </strong>This study highlights the significant impact of night shifts on the physical and mental health of psychiatric medical staff. The findings suggest that interventions to reduce the negative impacts of night shifts are crucial, such as improving shift systems, increasing organizational support, and providing targeted mental health programs. These measures will help enhance night shift workers' health and job satisfaction, improving the overall quality of health care services.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"256"},"PeriodicalIF":3.4,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11921728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}