BMC Psychiatry最新文献

{"title":"Association between fasting blood glucose and psychotic symptoms in Chinese patients with first-episode drug-naïve major depressive disorder.","authors":"Xingzhi Xia, Hanxu Deng, Wei Ren, Lin Yang, Yingzhao Zhu, Yaozhi Liu, Junjun Liu, Xueli Zhao, Fengnan Jia, Xiangdong Du, Xiangyang Zhang","doi":"10.1186/s12888-025-06502-2","DOIUrl":"10.1186/s12888-025-06502-2","url":null,"abstract":"<p><strong>Introduction: </strong>Psychotic depression (PD) is a highly debilitating disorder characterized by hallucinations and/or delusions accompanied by depression. A variety of neurotransmitters, hormones and corresponding receptors in the endocrine system are involved in the onset and progression of depression, and fasting blood glucose (FBG) can be an important indicator for monitoring the stability of the endocrine system. The aim of this study was to investigate the relationship between FBG and PD in a Chinese population with first-episode drug-naïve (FEDN) major depressive disorder (MDD).</p><p><strong>Methods: </strong>In this study, 1718 outpatient individuals diagnosed with first-episode drug-naïve major depressive disorder (FEDN MDD) were included. The association between PD and FBG levels was identified through multivariable binary logistic regression analysis. To investigate potential non-linear relationships, a two-piecewise linear regression model was utilized. Additionally, interaction and stratified analyses were performed based on gender, educational background, marital status, presence of comorbid anxiety, and history of suicide attempt.</p><p><strong>Results: </strong>Multivariate logistic regression analysis showed that FBG was positively associated with the risk of PD in FEDN MDD patients (OR = 1.68, 95% CI: 1.31 to 2.13; P < 0.05). Smoothed plots showed a non-linear relationship between FBG and PD, while the inflection point of FBG was calculated using a two-segmented logistic regression model to be 6.23 mmol/L. On the right side of the inflection point, the probability of PD increased substantially by 278% (OR = 3.78, 95% CI: 1.75 to 8.18, p < 0.001), while no significant association was observed on the left side of the inflection point (OR = 1.06, 95% CI: 0.73 to 1.52, p = 0.772).</p><p><strong>Conclusions: </strong>Our investigation revealed a nonlinear relationship between FBG and PD in patients with FEDN MDD, thereby informing more effective intervention strategies for managing psychotic symptoms in individuals with depression.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"49"},"PeriodicalIF":3.4,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745022/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142999630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic impact of psychoeducation program completion on inpatients with schizophrenia: a pilot cohort study.","authors":"Hiroki Noguchi, Seiichiro Tarutani, Yoshiki Takei, Koichi Matsumoto, Takehiko Okamura, Hiroshi Yoneda","doi":"10.1186/s12888-024-06397-5","DOIUrl":"10.1186/s12888-024-06397-5","url":null,"abstract":"<p><strong>Background: </strong>Psychoeducation programs can reduce the risk of recurrence and readmission in patients with schizophrenia. However, almost all previous studies of program efficacy have included only patients completing the program, which may not be possible in all cases. The objective of this pilot cohort study was to compare the prognoses of inpatients with schizophrenia who did or did not complete a well-established institutional psychoeducation program.</p><p><strong>Methods: </strong>This study is a pilot cohort study, and the participants were 32 inpatients in the psychiatric acute care ward. Among these patients, 18 completed the institutional psychoeducation program by discharge, whereas 14 missed one or more sessions for various reasons. The primary outcome was the duration of outpatient treatment (DOT) during the 5-year follow-up period, and the secondary outcomes were comparisons of the risk of all-cause discontinuation for outpatient treatment and correlations between the program participation rates and DOT.</p><p><strong>Results: </strong>DOT was significantly longer in the program completion group than in the noncompletion group (918.2 (174.3) days vs. 225.5 (35.7) days, p = 0.001), and multivariate Cox proportional hazards regression analysis revealed that program noncompliance was associated with a 4.450-fold (p = 0.002) greater risk of discontinuation of outpatient treatment according to multivariate analysis. A significant weak correlation was found for DOT and rates of sessions admitted to the programme (Pearson's r = 0.384, p = 0.030).</p><p><strong>Conclusions: </strong>Completion of a psychoeducation program could enhanced the success of outpatient treatment. As psychoeducation and related factors may have a positive effect of the prognosis after discharge, inpatient psychoeducation programs should be flexible enough to provide opportunities for completion.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"50"},"PeriodicalIF":3.4,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142999681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are neurasthenia and depression the same disease entity? An electroencephalography study.","authors":"Ge Dang, Lin Zhu, Chongyuan Lian, Silin Zeng, Xue Shi, Zian Pei, Xiaoyong Lan, Jian Qing Shi, Nan Yan, Yi Guo, Xiaolin Su","doi":"10.1186/s12888-025-06468-1","DOIUrl":"10.1186/s12888-025-06468-1","url":null,"abstract":"<p><strong>Background: </strong>The neurasthenia-depression controversy has lasted for several decades. It is challenging to solve the argument by symptoms alone for syndrome-based disease classification. Our aim was to identify objective electroencephalography (EEG) measures that can differentiate neurasthenia from major depressive disorder (MDD).</p><p><strong>Methods: </strong>Both electronic medical information records and EEG records from patients with neurasthenia and MDD were gathered. The demographic and clinical characteristics, EEG power spectral density, and functional connectivity were compared between the neurasthenia and MDD groups. Machine Learning methods such as random forest, logistic regression, support vector machines, and k nearest neighbors were also used for classification between groups to extend the identification that there is a significant different pattern between neurasthenia and MDD.</p><p><strong>Results: </strong>We analyzed 305 patients with neurasthenia and 45 patients with MDD. Compared with the MDD group, patients with neurasthenia reported more somatic symptoms and less emotional symptoms (p < 0.05). Moreover, lower theta connectivity was observed in patients with neurasthenia compared to those with MDD (p < 0.01). Among the classification models, random forest performed best with an accuracy of 0.93, area under the receiver operating characteristic curve of 0.97, and area under the precision-recall curve of 0.96. The essential feature contributing to the model was the theta connectivity.</p><p><strong>Limitations: </strong>This is a retrospective study, and medical records may not include all the details of a patient's syndrome. The sample size of the MDD group was smaller than that of the neurasthenia group.</p><p><strong>Conclusion: </strong>Neurasthenia and MDD are different not only in symptoms but also in brain activities.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"44"},"PeriodicalIF":3.4,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11742223/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142999627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Common mental disorders and associated factors among adult patients admitted in non-psychiatric wards of public hospitals in Harari regional State, Eastern Ethiopia.","authors":"Hirko Assefa, Tilahun Ali, Ibsa Mussa, Tadesse Misgana, Dawit Abdi, Abinet Zewudie, Abdi Temesgen","doi":"10.1186/s12888-025-06475-2","DOIUrl":"10.1186/s12888-025-06475-2","url":null,"abstract":"<p><strong>Introduction: </strong>Common mental disorders represent psychiatric co-morbidity in medical illness, which leads to poor adherence to treatment, increased exposure to diagnostic procedures and the cost of treatment, longer hospital stay, and increasing the risk of complications that result in morbidity and mortality among patients admitted to non-psychiatric wards. There is a dearth of evidence related to the prevalence of common mental disorders and associated factors among adult patients admitted to non-psychiatric wards, particularly in the study area. This study aimed to assess the prevalence of common mental disorders and associated factors among adult patients admitted to non-psychiatric wards of public hospitals in the Harari region, eastern Ethiopia.</p><p><strong>Methods: </strong>An institutional-based cross-sectional study was conducted among 640 randomly selected patients admitted to non-psychiatric wards from November 15 to December 15, 2022. A systematic random sampling technique was employed to select the study participants. Data were collected by interviewer-administered structured and semi-structured questionnaires. Self-report questionnaire (SRQ-20) was used to assess the presence of common mental disorders. The collected data were entered into Epi-data version 3.1 and exported to STATA version 14 for analysis. Bivariable and multivariable logistic regression were used to evaluate the association between independent and the outcome variable. Variables with a p-value < 0.05 were taken as statistically significant with an adjusted odds ratio and 95% confidence interval.</p><p><strong>Results: </strong>The prevalence of common mental disorders among adult patients admitted to non-psychiatric wards was found to be 45.3%, with a 95% CI: of 41.3-49.2. Age 41-51 years (AOR = 1.732, 95% CI: 1.030, 2.913), age 51 and above (AOR = 2.429, 95% CI: 1.515, 3.894), staying at hospital for 1-2 weeks (AOR = 1.743, 95% CI: 1.065, 2.853), staying at hospital for more than 4 weeks (AOR = 2.12, 95% CI: 1.77, 3.29), history of mental illness (AOR = 5.841, 95% CI: 2.274, 15.004), stressful life events (AOR = 1.876, 95% CI: 1.206, 2.9196), current substance use (AOR = 1.688, 95% CI: 1.75, 2.650), and poor social support (AOR = 2.562, 95% CI:1.166, 5.629) were factors significantly associated with common mental disorders.</p><p><strong>Conclusion: </strong>The prevalence of common mental disorders among patients admitted to non-psychiatric wards was high. It appears to be significantly associated with age, length of hospital stay, history of mental illness, stressful life events, current substance use, and social support. The study suggested that patients who are admitted to non-psychiatric wards should be screened for common mental disorders and its associated factors as part of routine inpatient care.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"47"},"PeriodicalIF":3.4,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11742786/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142999227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sociodemographic and clinical determinants of suicidal ideation: an analysis in a Peruvian consultation-liaison psychiatry unit.","authors":"Jeff Huarcaya-Victoria, José Salvador-Carillo, Michaell Cabrejos-Espinoza, Mercedes Ponce-Pantigoso, Kelly Broncano-Rivera, Andrea Loarte-Cabrera","doi":"10.1186/s12888-025-06480-5","DOIUrl":"10.1186/s12888-025-06480-5","url":null,"abstract":"<p><strong>Background: </strong>Suicidal ideation (SI) poses a significant global health concern, particularly among hospitalized individuals, with gaps in understanding its contributing factors in low and middle-income countries like Peru.</p><p><strong>Methods: </strong>Using a cross-sectional design, this study examined 940 patients evaluated by the Consultation-Liaison Psychiatry Unit at a major Peruvian general hospital. Sociodemographic and clinical characteristics were assessed, employing standardized instruments such as the Patient Health Questionnaire-9 (PHQ-9), General Anxiety Disorder Scale (GAD-7), Patient Health Questionnaire-15 (PHQ-15), and Clinical Global Impressions (CGI). The prevalence of SI and its associations were explored through bivariate and multivariate analyses.</p><p><strong>Results: </strong>The prevalence of SI was 19.7%, with notable associations found in patients experiencing moderate-to-severe depression (36.8%) and those rated as moderately to severely ill on CGI (33.2%). Multivariate analysis confirmed these associations, highlighting link with retirement (aPR = 1.53, 95% CI = 1.04-2.26, p = 0.032), clinical severity (aPR = 1.41, 95% CI = 1.22-1.63, p < 0.0001), and depressive symptoms (aPR = 2.98, 95% CI = 2.13-4.17, p < 0.0001) on SI.</p><p><strong>Conclusion: </strong>This study provides insights into factors associated with SI among hospitalized patients. Identifying risk factors, such as retirement, clinical severity, and depressive symptoms, underscores the need for targeted interventions to address SI within the Peruvian general hospital setting.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"45"},"PeriodicalIF":3.4,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11742514/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142999702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The factors influencing self-management in patients with depression: a qualitative research from China.","authors":"Ying-Li Gao, Lu-Xia Shen, Xiu-Mei Hou, Shu-Ping Si, Huan-Huan Zhu, Zhong-Li Shi","doi":"10.1186/s12888-025-06489-w","DOIUrl":"10.1186/s12888-025-06489-w","url":null,"abstract":"<p><strong>Background: </strong>As depressed patients often fail to seek help and obtain treatment on time for reasons such as stigma and lack of treatment resources, research on self-management for depressed patients is crucial. This study aimed to explore the factors influencing self-management in depression patients from the perspectives of both patients and psychiatric nurses.</p><p><strong>Methods: </strong>Six depression patients and twelve psychiatric nurses were chosen for semi-structured interviews through a purposive sampling method from a tertiary Grade A psychiatric hospital in Shandong Province, China. The group of depressed patients included in the study had a male to female sex ratio of 1:1 with a mean age of 46years. The psychiatric nurse group had a male to female ratio of 1:2 with a mean age of 42.42 years. We used descriptive qualitative research techniques. Nvivo 12.0 software was used for the data management and analysis using thematic analysis.</p><p><strong>Results: </strong>The factors influencing the self-management of depression patients were summarized into three themes and eight sub-themes: disease impact (symptoms, stigma), the degree of symptom control (medication adherence, depression's cognitive status, its treatment and rehabilitation as well as additional factors), and support (self-efficacy, external support).</p><p><strong>Conclusions: </strong>This study found that multiple factors influence the self-management of depression patients, including disease impact, the degree of symptom control, and support. In addition to helping patients integrate social resources and seek social support, medical staff should also pay attention to changes in the patient's condition and disease control. Moreover, they should help patients increase their self-efficacy and enhance their self-management abilities through health education and other means.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"48"},"PeriodicalIF":3.4,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11742202/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142999718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Common and distinct neural underpinnings of the association between childhood maltreatment and depression and aggressive behavior.","authors":"Yuan Li, Ting Zhang, Xin Hou, Xiaoyi Chen, Yu Mao","doi":"10.1186/s12888-025-06485-0","DOIUrl":"10.1186/s12888-025-06485-0","url":null,"abstract":"<p><strong>Background: </strong>Although childhood maltreatment (CM) is widely recognized as a transdiagnostic risk factor for various internalizing and externalizing psychological disorders, the neural basis underlying this association remain unclear. The potential reasons for the inconsistent findings may be attributed to the involvement of both common and specific neural pathways that mediate the influence of childhood maltreatment on the emergence of psychopathological conditions.</p><p><strong>Methods: </strong>This study aimed to delineate both the common and distinct neural pathways linking childhood maltreatment to depression and aggression. First, we employed Network-Based Statistics (NBS) on resting-state functional magnetic resonance imaging (fMRI) data to identify functional connectivity (FC) patterns associated with depression and aggression. Mediation analyses were then conducted to assess the role of these FC patterns in the relationship between childhood maltreatment and each outcome.</p><p><strong>Results: </strong>The results demonstrated that FC within the default mode network (DMN) and between the cingulo-opercular network (CON) and dorsal attention network (DAN) mediated the association between childhood maltreatment and aggression, whereas FC within the reward system and between the CON and the reward system mediated the link between childhood maltreatment and depression.</p><p><strong>Conclusions: </strong>We speculate that the control system may serve as a transdiagnostic neural basis accounting for the sequela of childhood maltreatment, and the attention network and the reward network may act as specific neural basis linking childhood maltreatment to depression and aggression, respectively.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"43"},"PeriodicalIF":3.4,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11740468/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142999212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of psychotropic pro re nata prescription-monitoring programme on prescriptions for inpatients with psychiatric disorders: a retrospective observational study.","authors":"Yoshitaka Saito, Kyohei Sumida, Hiroyuki Muraoka, Satoru Oishi, Ryutaro Suzuki, Taiyo Nishikawa, Shin Miyake, Yukihiro Tanno, Yuki Tobita, Katsuya Otori, Ken Inada","doi":"10.1186/s12888-025-06508-w","DOIUrl":"10.1186/s12888-025-06508-w","url":null,"abstract":"<p><strong>Background: </strong>Pro re nata (PRN) medication is used \"as needed\" for symptoms such as agitation and insomnia, in addition to regular daily pharmacotherapy of mental disorders. However, there is no high-quality evidence on the effectiveness of psychotropic PRN medications and concerns have been raised about their potential to contribute to polypharmacy. This study introduced a psychotropic PRN prescription-monitoring programme for psychiatric inpatients with the aim of examining the change before and after the implementation of the programme.</p><p><strong>Method: </strong>This study included 389 patients admitted to the psychiatric department between 1 July 2021 and 30 June 2023. The psychotropic PRN prescription-monitoring programme was implemented in July 2022, and the participants were classified into monitoring and non-monitoring groups. Demographic data (age, sex, and diagnosis), regular prescriptions before admission and at discharge, psychotropic PRN prescriptions before admission and at discharge, and the total number of psychotropic PRN prescriptions during hospitalisation were compared between the two groups. Data on psychotropic prescription were collected by psychotropic category. The significance level of 5% was set at 1.67 × 10^-3 using the Bonferroni correction for multiple testing.</p><p><strong>Results: </strong>The psychotropic PRN prescription ratio at discharge in the monitoring group was 9.3%, which was significantly lower than the 28.1% in the non-monitoring group. The percentage of patients with a PRN prescription during hospitalisation in the monitoring group was 29.8%, which was significantly lower than the 64.5% in the non-monitoring group. In the non-monitoring group, there was no statistically significant difference in the number of psychotropic drugs prescribed regularly before and after admission. However, in the monitoring group, the number of psychotropic drugs in the regular prescriptions at discharge was 1.87 ± 1.24, which was significantly lower than 2.47 ± 1.90 in the regular prescription before admission.</p><p><strong>Conclusions: </strong>Our findings suggest that a psychotropic PRN prescription-monitoring programme may contribute to the elimination of polypharmacy, including regular prescriptions. Further research is required to optimise psychotropic PRN prescriptions and reduce polypharmacy.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"46"},"PeriodicalIF":3.4,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11742780/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142999634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Childhood cancer and parental mental health: role of disease severity, socioeconomic status, and social dynamics.","authors":"Hawkar Ibrahim, Azad Ali Ismail, Narin Ahmed Rahim, Benjamin Iffland, Frank Neuner","doi":"10.1186/s12888-025-06494-z","DOIUrl":"10.1186/s12888-025-06494-z","url":null,"abstract":"<p><strong>Background: </strong>The impact of childhood cancer extends beyond the affected child, significantly influencing the mental health of their families. Since research in psycho-oncology has been carried out almost exclusively in high-income countries, little is known about the impact of childhood cancer on the family level in low- and middle income countries (LMICs). This is a notable gap in the evidence-base, as many LMICs are collectivist cultures, where social and family networks are crucial elements of health care.</p><p><strong>Methods: </strong>This prospective, cross-sectional study examined the mental health of 307 Kurdish parents of children undergoing cancer treatment in the Kurdistan Region of Iraq (KRI). Data were collected through structured interviews at two major oncology hospitals in the KRI, utilizing standardized instruments to assess mental health symptoms, socioeconomic status, and social constraints. The study focused on understanding the effects of socioeconomic challenges, disease severity, and social support limitations on parental mental health.</p><p><strong>Results: </strong>Significant mental health challenges were observed among parents, with mothers experiencing higher symptom levels than fathers. Lower socioeconomic status was linked to poorer parental mental health. Additionally, parents of children with more severe cancer and those reporting their child's reduced engagement in daily activities experienced heightened mental health symptoms. Social constraints on expressing feelings about the child's illness further intensified parental stress, underscoring the cumulative impact of economic strain, disease severity, and limited social support on parental mental health.</p><p><strong>Conclusions: </strong>The study highlights the intricate relationship between socioeconomic factors, the disease severity of the child, and social dynamics in shaping parental mental health in the context of pediatric cancer. Psychosocial interventions that target these specific stressors may aid in better supporting families, particularly those in low-resource settings.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"42"},"PeriodicalIF":3.4,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11740337/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142999636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dyadic effects of illness perception and maladaptive cognitive-emotional regulation strategies on the fear of cancer recurrence in breast cancer patients and spouses: an actor-partner interdependence mediation model.","authors":"Hui Ren, Tianye Yang, Songli Mei, Zhu Zhu, Jianjun Shi, Lingling Tong, Jia Yang, Yabin Sun","doi":"10.1186/s12888-024-06354-2","DOIUrl":"10.1186/s12888-024-06354-2","url":null,"abstract":"<p><strong>Purpose: </strong>Breast cancer, as a stressful event, profoundly impacts the entire family, especially patients and their spouses. This study used a dyadic analysis approach to explore the dyadic effects of illness perception on the fear of cancer recurrence (FCR) and whether maladaptive cognitive-emotional regulation strategies acted as a mediator in breast cancer patient-spouse dyads.</p><p><strong>Methods: </strong>This was a cross-sectional study, and 202 dyads of breast cancer patients and their spouses were enrolled. Illness perception, maladaptive cognitive-emotional regulation strategies, and FCR were assessed by the Brief Illness Perception Questionnaire (BIPQ), the Cognitive Emotion Regulation Questionnaire (CERQ), and the Fear of Cancer Recurrence Inventory Short Form (FCRI-SF), respectively. Data were analyzed using the actor-partner interdependence mediation model.</p><p><strong>Results: </strong>This study found that, for patients and spouses, maladaptive cognitive-emotional regulation strategies mediated the actor effects of illness perception on FCR. That is, illness perception was positively related to their maladaptive cognitive-emotional regulation strategies, which increased the risk of FCR. Another important finding was that patients' illness perception had significant direct and indirect effects on spouses' FCR through spouses' maladaptive cognitive-emotional regulation strategies.</p><p><strong>Conclusions: </strong>Negative illness perception perceived by patients and spouses can increase their FCR by adapting their maladaptive cognitive-emotional regulation strategies. Furthermore, illness perception perceived by patients can also increase spouses' FCR through spouses' maladaptive cognitive-emotional regulation strategies. Medical staff should identify vulnerable patients and spouses with higher illness perception and maladaptive cognitive-emotional regulation strategies and make focused interventions to decrease the risk of FCR of both breast cancer patients and their spouses.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"41"},"PeriodicalIF":3.4,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11737191/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142999254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}