BMC Psychiatry最新文献

{"title":"Understanding functioning in schizophrenia through the lens of social cognition: a phenomenological study.","authors":"Azam Salarhaji, Hossein Karimi Moonaghi, Masoud Kashani-Lotfabadi, Hossein Namdar Areshtanab, Farhad Faridhosseini","doi":"10.1186/s12888-025-07290-5","DOIUrl":"10.1186/s12888-025-07290-5","url":null,"abstract":"","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"900"},"PeriodicalIF":3.4,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486862/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145197908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Older adults' perceptions and needs regarding mental health WeChat applet: a qualitative study.","authors":"Yu-Fei Qiu, Jia-Li Liu, Li-Juan Zeng, Yi-Qing Yu, Ya-Ke Yue, Juan Gu, Meng-Jie Tong, Fen Yang, Gang Chen, Yang-Yang Han","doi":"10.1186/s12888-025-07339-5","DOIUrl":"10.1186/s12888-025-07339-5","url":null,"abstract":"<p><strong>Background: </strong>Mental health issues among older adults represent a major burden of disease worldwide. In China, WeChat applets have emerged as a promising tool for delivering mental health support, offering a solution to the accessibility and personalization limitations of conventional psychotherapy. However, the perceptions and needs of older adults regarding mental health WeChat applets remain unclear.</p><p><strong>Objective: </strong>To explore older adults' perceptions and needs for mental health WeChat applets.</p><p><strong>Methods: </strong>We carried out a qualitative descriptive design. Sixteen participants were recruited from four communities in Wuhan, Hubei Province, using purposive sampling and snowball sampling. Face to face semi-structured in-depth interviews were conducted with them from January 15 to 25, 2025. Data were analysed using inductive content analysis.</p><p><strong>Results: </strong>Three main themes were identified in this study: (1) Attitudes and perceptions, (2) Functional needs, and (3) Preferences for design and usability. Nine sub-themes were also identified.</p><p><strong>Conclusion: </strong>This study explored older adults' attitudes and needs regarding mental health WeChat applets. The findings highlighted the importance of user-centered design, transparent data protection, and digital literacy support. Additionally, policy efforts should integrate mental health awareness into public health strategies and engage multiple stakeholders, including healthcare providers, community workers, policymakers, technology developers, and family members, to enhance the acceptance and effectiveness of digital mental health tools for older adults.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"889"},"PeriodicalIF":3.4,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145198166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subcortical volume alteration and correlation with social function under chlorpromazine versus clozapine treatment in schizophrenia.","authors":"Ju Gao, Jinxing Jia, Qianqian Jiang, Ping Yang, Jin Li, Xiaobin Zhang, Xiangrong Zhang, Xiaowei Tang","doi":"10.1186/s12888-025-07309-x","DOIUrl":"10.1186/s12888-025-07309-x","url":null,"abstract":"<p><strong>Background: </strong>This investigation examines the differences in subcortical volume between schizophrenia patients treated with chlorpromazine (CPZ) or clozapine (CLZ) and healthy controls and examines how these antipsychotic treatments affect brain structure.</p><p><strong>Methods: </strong>Structural MRI (3T) was used to assess subcortical volumes in 24 CPZ-treated patients, 24 CLZ-treated patients, and 24 healthy controls. Clinical symptoms and social function were evaluated using PANSS and SSPI scales. Correlate and predictive analyses were performed to explore the relationship between the volume of subcortical structures and social functioning.</p><p><strong>Results: </strong>Analysis revealed a significant increase in pallidum and putamen volumes in the CPZ group compared to both the CLZ group and healthy controls. Thalamic volume was not significantly different between the CPZ and CLZ groups but was reduced compared to controls. Exploratory analysis suggested an association between total thalamic volume and social function in the CPZ group, though this finding did not remain significant after correction for multiple comparisons. According to the predictive analysis, only the whole thalamus and bilateral thalamus volume showed statistically significant effects on prediction of SSPI scores.</p><p><strong>Conclusions: </strong>Our results suggest that distinct neuroanatomical differences may be associated with various antipsychotic treatments in schizophrenia. These subcortical alterations may reflect differential pharmacological effects, and thalamic volume could represent a potential neuroimaging marker related to social function.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"887"},"PeriodicalIF":3.4,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145197821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research on the correlation of nitric oxide-induced neuronal cell pyroptosis with schizophrenia and its cognitive impairment.","authors":"Meijun Lei, Yu Tian, Zhaowei Teng, Xiaoqing Wang, Rong Yin, Yu Dai, Ying Yan, Fang Liu","doi":"10.1186/s12888-025-07333-x","DOIUrl":"10.1186/s12888-025-07333-x","url":null,"abstract":"","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"890"},"PeriodicalIF":3.4,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487045/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145197575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and psychometric evaluation of a questionnaire addressing the psychosocial needs of oocyte recipient women.","authors":"Shohre Ghelich-Khani, Ashraf Kazemi, Malek Fereidooni-Moghadam, Nafisehsadat Nekuei","doi":"10.1186/s12888-025-07330-0","DOIUrl":"10.1186/s12888-025-07330-0","url":null,"abstract":"","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"885"},"PeriodicalIF":3.4,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486673/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145198058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychosocial adversity and executive functions in children and adolescents: a systematic review of mediating and moderating influences of parenting behaviors.","authors":"Andressa Souza Cardoso, Rafaela Costa Martins, Bruna Venturin, Andrea Gonzalez, Cauane Blumenberg, Joseph Murray","doi":"10.1186/s12888-025-06592-y","DOIUrl":"10.1186/s12888-025-06592-y","url":null,"abstract":"<p><strong>Objective: </strong>Summarize the state of the evidence on potential mediating and moderating roles of parenting behaviors in the relationship between psychosocial adversity and executive functions among children and adolescents.</p><p><strong>Method: </strong>A systematic review was conducted by searching PubMed, Web of Science, Embase, and PsycINFO databases in June 2024, screening for eligible studies, in duplicate, and summarizing results from individual studies.</p><p><strong>Results: </strong>Twenty-one eligible studies were identified, 18 from the USA and Canada, and 3 from other countries. In 17 studies of mediation, developmentally supportive parenting behaviors and non-supportive parenting behaviors at least partly explained the relationship between adversity (low socioeconomic status, household chaos, intimate partner violence, and maternal depression) and executive functions. Among four studies testing moderation, two suggested that a context of developmentally supportive parenting behaviors (e.g., maternal sensitivity) may act as a protective factor, buffering the negative effects of adversity (low socioeconomic status) on executive functions.</p><p><strong>Conclusion: </strong>Parenting practices are potentially important intervening mechanisms explaining the effects of adversity on child executive functions, and developmentally supportive parenting behaviors could mitigate negative effects. However, the current evidence base is limited, particularly about potential buffering effects, and further research is needed across a wider range of countries and settings.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"894"},"PeriodicalIF":3.4,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487171/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145197565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of emotion regulation strategies on anxiety and depression among college students in confinement situation due to COVID-19: a relevance model of goal focus as a moderator.","authors":"Mengqi Xiao, Chenhao Zhang, Xuan Chen, Yueyue Su, Jiamin Wei, Yaling Zhuang, Jiaxuan Wu, Dingguo Gao, Jiahua Xu","doi":"10.1186/s12888-025-07303-3","DOIUrl":"10.1186/s12888-025-07303-3","url":null,"abstract":"<p><strong>Background: </strong>This study examines the impact of confinement measures implemented to prevent the spread of COVID-19 on the anxiety and depression levels of college students, particularly focusing on how the extended period of confinement significantly contributed to the deterioration of their mood states.</p><p><strong>Methods: </strong>The present quantitative study utilized a sample of 13,255 participants drawn from three universities located in Guangzhou City. To examine the impact of confinement, the sample included participants from two universities subject to confinement policies and one university without such restrictions. Data were collected via online surveys administered using Wenjuanxing, encompassing the Emotion Regulation Questionnaire (ERQ), the PHQ-9 Depression Screening Scale, the GAD-7 Anxiety Screening Scale, and the Resilience Scale.</p><p><strong>Results: </strong>The findings revealed that the effectiveness of cognitive reappraisal in mitigating anxiety (t = -8.132, p < 0.001) and depression (t = -8.423, p < 0.001) decreased in less confined environments, and could even reverse, becoming a factor contributing to increased anxiety (t = 2.794, p = 0.005) and depression (t = 2.332, p = 0.020) in highly confined settings with increasing levels of goal focus (t = 9.008, p < 0.001, anxiety; t = 7.408, p < 0.001, depression). Moreover, expressive suppression was found to positively correlate with both anxiety (t = 8.809, p < 0.001, highly confined; t = 3.001, p = 0.003, less confined) and depression (t = 8.324, p < 0.001, highly confined; t = 2.724, p = 0.007, less confined). Goal focus was observed to exacerbate its adverse effects on anxiety (t = 11.03, p < 0.001 in highly confined situations; t = 11.129, p < 0.001 in less confined situations) and on depression (t = 6.301, p < 0.001 in highly confined situations; t = 8.412, p < 0.001 in less confined situations).</p><p><strong>Conclusion: </strong>This research contributes valuable knowledge to the understanding of the complex interplay between emotional regulation, goal focus, and psychological well-being during times of crisis.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"881"},"PeriodicalIF":3.4,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486821/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145197835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A rare case of isovaleric acidemia and schizophrenia: a case report.","authors":"Jiawei Zhou, Hui Chen, Xianliang Chen, Huajia Tang, Sihong Li, Jiansong Zhou","doi":"10.1186/s12888-025-07239-8","DOIUrl":"10.1186/s12888-025-07239-8","url":null,"abstract":"<p><strong>Background: </strong>Schizophrenia is a severe chronic mental disorder characterized by hallucinations, delusions, and disorganized speech and behavior. On the other hand, isovaleric acidemia (IVA) is a rare metabolic disorder characterized by the accumulation of isovaleric acid and its metabolic byproducts in the body. To date, there is a notable absence of clinical descriptions concerning the simultaneous occurrence of IVA and schizophrenia in the existing literature.</p><p><strong>Case presentation: </strong>This report presents a clinical case involving the coexistence of IVA and Schizophrenia. A 25-year-old male patient diagnosed with comorbid IVA and schizophrenia was admitted to the psychiatric department due to worsening delusions and auditory hallucinations. Treatment with antipsychotics (clozapine 150 mg/day and blonanserin 24 mg/day) and metabolic agents (L-carnitine 3 g/day and reduced glutathione 1.2 g/day) reduced delusion severity, though delusions persisted, while auditory hallucinations resolved.</p><p><strong>Conclusions: </strong>In this case description, the authors describe a rare clinical case in which the patient presents with IVA and schizophrenia. This case discusses the potential pathways through which IVA may precipitate the onset of schizophrenia.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"897"},"PeriodicalIF":3.4,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12487407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145198040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between smartphone addiction and creativity in Chinese college students: the chain mediating effects of depression and executive function.","authors":"Wenfu Li, Jinmei Liu, Xia Liu, Yao Ge, Yan Wang, Aoxue Zhang","doi":"10.1186/s12888-025-07378-y","DOIUrl":"10.1186/s12888-025-07378-y","url":null,"abstract":"<p><strong>Background: </strong>Smartphone addiction has emerged as a widespread public health concern, especially among college students. This study examines the association between smartphone addiction and creativity among Chinese college students, as well as the underlying psychological mechanisms involved. A serial mediation model framework was conducted to explore the effect of smartphone addiction on creativity, taking into consideration the mediating roles of depression and executive function.</p><p><strong>Methods: </strong>In this study, a sample of 691 Chinese college students was surveyed using the Mobile Phone Addiction Index, the Centre for Epidemiologic Studies - Depression Scale, the Behavior Rating Inventory of Executive Function - Adult Version, and the University Students' Creativity Scale to examine the impact mechanism of smartphone addiction on creativity. Correlation and mediation model analyses were performed respectively using SPSS 22.0 and PROCESS 3.1.</p><p><strong>Results: </strong>Correlation analysis showed that smartphone addiction was positively correlated with depression (r = 0.298, P < 0.001) and executive function impairment (r = 0.677, P < 0.001), while it was negatively associated with creativity (r = -0.209, P < 0.001). Additionally, depression was positively correlated with executive function impairment (r = 0.376, P < 0.001). Furthermore, creativity was negatively associated with depression (r =-0.143, P < 0.001) and executive function impairment (r = -0.291, P < 0.001). The mediation analysis indicated that smartphone addiction directly negatively predicted creativity, and also indirectly predicted creativity through the serial mediating role of depression and executive function impairment.</p><p><strong>Conclusion: </strong>Smartphone addiction not only directly affected creativity, but also indirectly influenced it through both the independent mediating role of executive function, as well as their serial mediation pathway.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"901"},"PeriodicalIF":3.4,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486723/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145197863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Marital control, domestic violence justification, and mental health: a study of married women in Bangladesh.","authors":"Mortuja Mahamud Tohan, Sayeeda Zaman, Bristi Rani Saha, Nushrath Jahan Juhi, Shaiya Binte Mahbub, Md Hasan Howlader","doi":"10.1186/s12888-025-07133-3","DOIUrl":"10.1186/s12888-025-07133-3","url":null,"abstract":"","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"886"},"PeriodicalIF":3.4,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12486741/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145198087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}