BMC Psychiatry最新文献

{"title":"Utilizing machine learning algorithms for predicting Anxiety-Depression Comorbidity Syndrome in Gastroenterology Inpatients (ADCS-GI).","authors":"Min Tan, Jinjin Zhao, Yushun Tao, Uroosa Sehar, Yan Yan, Qian Zou, Qing Liu, Long Xu, Zeyang Xia, Lijuan Feng, Jing Xiong","doi":"10.1186/s12888-025-06666-x","DOIUrl":"10.1186/s12888-025-06666-x","url":null,"abstract":"<p><strong>Background: </strong>Accurately diagnosing Anxiety-Depression Comorbidity Syndrome in Gastroenterology Inpatients (ADCS-GI) shows significant challenges as traditional diagnostic methods fail to meet expectations due to patient hesitance and non-psychiatric healthcare professionals' limitations. Therefore, the need for objective diagnostics highlights the potential of machine learning in identifying and treating ADCS-GI.</p><p><strong>Methods: </strong>A total of 1186 ADCS patients were recruited for this study. We conducted extensive studies for the dataset, including data quantification, equilibrium, and correlation analysis. Eight machine learning models, including Gaussian Naive Bayes (NB), Support Vector Classifier (SVC), K-Neighbors Classifier, RandomForest, XGB, CatBoost, Cascade Forest, and Decision Tree, were utilized to compare prediction efficacy, with an effort to minimize the dependency on subjective questionnaires.</p><p><strong>Results: </strong>Among eight machine learning algorithms, the Decision Tree and K-nearest neighbors models demonstrated an accuracy exceeding 81% and a sensitivity in the same range for detecting ADCS in patients. Notably, when identifying moderate and severe cases, the models achieved an accuracy above 88% and a sensitivity of 90%. Furthermore, the models trained without reliance on subjective questionnaires showed promising performance, indicating the feasibility of developing questionnaire-free early detection applications.</p><p><strong>Conclusion: </strong>Machine learning algorithms can be used to identify ADCS among gastroenterology patients. This can help facilitate the early detection and intervention of psychological disorders in gastroenterology patients' care.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"253"},"PeriodicalIF":3.4,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11921569/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143655950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceived determinants of the use of coercion in inpatient child and adolescent psychiatry: a qualitative interview study with staff.","authors":"Astrid Moell, Alexander Rozental, Susanne Buchmayer, Riittakerttu Kaltiala, Niklas Långström","doi":"10.1186/s12888-025-06690-x","DOIUrl":"10.1186/s12888-025-06690-x","url":null,"abstract":"<p><strong>Background: </strong>Understanding factors influencing the use of coercive practices in clinical psychiatry is necessary to develop strategies to reduce their use. However, there is little evidence regarding staff perceptions of such factors, particularly in inpatient child and adolescent psychiatry (CAP).</p><p><strong>Methods: </strong>We conducted semi-structured interviews with nurses, senior consultants and heads of units in inpatient CAP in Sweden 2021 (N = 9). The interviews were transcribed verbatim and analysed using reflexive thematic analysis. Data on informal coercion were analysed separately using a deductive approach based on previously proposed hierarchies for informal coercion.</p><p><strong>Results: </strong>We identified one overarching theme of factors reported to influence the use of coercive practices: \"Trust and distrust in coercive and non-coercive approaches\", in turn encompassing the two subthemes \"Ward culture\" and \"Available resources and strain\". Our findings suggest a risk of a negative spiral of coercion emerging when there is low professional trust in non-coercive approaches and high trust in coercive methods. Informal coercion was used frequently and observed to occur in two distinct processes: one concerning continuous coercive escalation, and the other involving sustained efforts at the same coercion level.</p><p><strong>Conclusions: </strong>Trusting the efficacy of non-coercive approaches in inpatient CAP care appears critical for their success; a finding that may inform strategies to reduce coercion and address frequent use with individual patients.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"246"},"PeriodicalIF":3.4,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11912791/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in dementia risk along with onset age of depression: a longitudinal cohort study of elderly depressed patients.","authors":"Yoo Jin Jang, Min-Ji Kim, Young Kyung Moon, Shinn-Won Lim, Doh Kwan Kim","doi":"10.1186/s12888-025-06683-w","DOIUrl":"10.1186/s12888-025-06683-w","url":null,"abstract":"<p><strong>Background: </strong>Depression in late-life is linked to an increased risk of Alzheimer's dementia (AD), with the risk potentially varying according to the age at onset of depression. Previous studies have typically dichotomized depression onset ages between 55 and 65 years; however, the specific age at which depression onset increases AD risk in older adults remains unclear. In this study, we aimed to investigate the relationship between the age at onset of depression and AD risk, and compare the characteristics between different age groups.</p><p><strong>Methods: </strong>A longitudinal cohort of 251 older patients diagnosed with major depressive disorder was followed for up to 22 years. Participants were categorized into four groups based on depression onset age: ≤ 54 years, 55-64, 65-74, and ≥ 75 years. Annual cognitive assessments were conducted using the Korean Mini-Mental State Examination, with further neuropsychological testing when cognitive decline was suspected. Cox proportional hazards models were used to assess AD conversion risk across groups, adjusting for covariates.</p><p><strong>Results: </strong>During follow-up ranging from 1.0 to 22.9 years, 75 patients (29.88%) converted to AD. Depression onset after age 75 years was significantly associated with a higher risk of AD conversion (hazard ratio [HR], 8.95; 95% confidence interval [CI], 3.41-23.48; p < 0.0001) and a shorter time to conversion compared to onset before age 55 (40.93 vs. 83.40 months). After adjusting for covariates, depression onset after age 75 remained significantly associated with AD conversion (adjusted HR, 5.20; 95% CI, 1.04-25.93; p = 0.0431). This group also had milder depressive symptoms and a higher prevalence of hypertension and cerebrovascular disease than those with depression onset before 55 years of age.</p><p><strong>Conclusions: </strong>The onset of depression after the age of 75 years was strongly associated with an increased risk of AD and a shorter time to dementia onset. Individuals with depression onset after age 75 appear more closely linked to vascular comorbidities, while those with depression onset before age 55 are characterized by severe and recurrent depressive episodes. The mechanisms underlying AD in individuals with depression may differ from those in individuals without prior depression.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"247"},"PeriodicalIF":3.4,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11917000/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital multimodal intervention for cancer-related cognitive impairment in breast-cancer patients: Cog-Stim feasibility study.","authors":"Giulia Binarelli, Florence Joly, François Christy, Bénédicte Clarisse, Marie Lange","doi":"10.1186/s12888-025-06630-9","DOIUrl":"10.1186/s12888-025-06630-9","url":null,"abstract":"<p><strong>Background: </strong>This feasibility study evaluated adherence and effectiveness to a digital multimodal intervention (cognitive and physical training) for cancer-related cognitive impairment (CRCI) in patients with breast cancer.</p><p><strong>Methods: </strong>Breast cancer patients undergoing radiotherapy and with significant cognitive complaints impacting quality of life participated in a 12-week intervention, combining non-simultaneous 20-min cognitive and 30-min physical sessions, twice weekly. Assessments included perceived cognitive impairment (PCI), objective cognition, fatigue, anxiety/depression, sleep and satisfaction. High level of adherence was defined as completing 9/12 weeks of the program. A week was complete when at least 70% of each of the planned sessions was completed. Physical activity intensity was defined by max age-related heart rate.</p><p><strong>Results: </strong>Among 419 radiotherapy-treated patients with breast cancer, 170 had cognitive complaints (41%), 83 were eligible (49%), 29 were not included (35%) due to organizational issue and 20 among eligible contacted patients agreed to participate (37%). The majority of participants (48.3 ± 8 years of age) received chemotherapy (18/20) and 17 had I-II cancer stage. Eleven of twenty participants were highly adherent (higher adherence in physical (95%) than cognitive training (55%)). All expressed satisfaction. Post-intervention, overall objective cognition (p = 0.016), PCI (p = 0.004), fatigue (p = 0.011), and depression (p = 0.049) significantly improved. Post-intervention, high adherence was associated with significant improvements in PCI (p = 0.01) and fatigue (p = 0.03). High-intensity physical training was associated with significant improvements in PCI (p < 0.05), fatigue (p = 0.011) and depression (p = 0.037).</p><p><strong>Conclusions: </strong>This intervention showed to be feasible and potentially efficient for the management of CRCI in patients with breast cancer.</p><p><strong>Trial registration: </strong>NCT04213365, 27/12/2019.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"249"},"PeriodicalIF":3.4,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11916931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the impact of an innovate behavioral health clinic: a retrospective cohort study.","authors":"Shaina Schwartz, Jakub Michel, Emma Brown, Mallory Bullard, Chak Yui Martin Chan, Joshua Doolittle, Kathryn Harrison, Alex Pashayan, Julie Nguyen, Archana Kumar","doi":"10.1186/s12888-025-06669-8","DOIUrl":"10.1186/s12888-025-06669-8","url":null,"abstract":"<p><strong>Background: </strong>Patients experiencing a mental health crisis often present to the emergency department and are admitted to an inpatient facility for treatment. This can cause incontinuity in care, increased costs, and may worsen clinical outcomes compared to treatment in the outpatient setting. An innovative behavioral health clinic (BHC) was established to provide a number of critical mental health services such as individual therapy, crisis stabilization, partial hospitalization, substance abuse intensive outpatient services, specialized intensive adult group therapy, medication management (including long-acting injectable antipsychotic administration), and a peer living room. The primary outcome of this study was to assess the impact of the BHC on length of stay (LOS), psychiatric rehospitalization rate, and all-cause emergency department (ED) visits. The secondary outcome was to analyze the interaction of various patient characteristics with the primary outcome.</p><p><strong>Methods: </strong>The study site was a community-based health system in the southeastern United States. A retrospective review of medical records was performed for adult patients with a psychiatric hospitalization in 2019 (pre-BHC) and 2022 (post-BHC). Primary outcomes were analyzed using Chi-Square testing and Mann-Whitney U testing. Secondary outcomes were analyzed using Poisson and logistic regression modeling. This study was deemed exempt from review by the health system and university institutional review boards.</p><p><strong>Results: </strong>Following the establishment of the BHC, mean LOS was significantly longer (+ 1.26 days, p = 0.001) and there was a statistically significant reduction in 30-day (-10.3%, p < 0.001) and 1-year (-28.2%, p < 0.001) rehospitalization as well as 30-day (-8.3%, p = 0.004) and 1-year (-13.5%, p < 0.001) ED visit rate. A diagnosis of schizophrenia and prescription of a LAI were associated with a significant increase in LOS, while being uninsured was associated with a significant decrease. Male gender and a diagnosis of schizophrenia were associated with a significant increase in ED visits, while identifying as White or Caucasian, being uninsured or carrying private insurance, and prescription of a LAI were associated with a significant decrease.</p><p><strong>Conclusions: </strong>The implementation of an innovative BHC positively impacted patient care outcomes in the study population. Patient characteristics were identified which independently interacted with these outcomes.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"250"},"PeriodicalIF":3.4,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11916986/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of motivational interviewing on patients with early post-stroke depression: a quasi-experimental study.","authors":"Yingjie Fu, Yi Zhang, Qianying Deng, Yuenv Wang, Siyi Su, Zheng Wang, Luyi Xu, Beibei Lin, Yun Li, Jufang Li","doi":"10.1186/s12888-025-06673-y","DOIUrl":"10.1186/s12888-025-06673-y","url":null,"abstract":"<p><strong>Background: </strong>Post-stroke depression (PSD) constitutes an important complication of stroke, affecting approximately one-third of stroke patients. PSD decreases rehabilitation motivation, delays function recovery, and increases the family and social burden of stroke patients. Motivational interviewing (MI) may be an effective and practical intervention strategy, but its effectiveness in improving PSD remains uncertain.</p><p><strong>Methods: </strong>A parallel two-group quasi-experimental study was conducted. Patients with early PSD were recruited from the neurology department of a hospital in southeast China and were allocated to the control group and intervention group by wards. Patients in the intervention group received one session of face-to-face motivational interviewing and three sessions of telephone motivational interviewing, while patients in the control group received routine nursing and follow-up of the neurology department. Outcomes including depression, sleep quality, and quality of life were evaluated at baseline (T0), after intervention immediately (T1) and three months after intervention (T2). Descriptive statistics, t-test, Mann-Whitney U test, Wilcoxon signed rank sum test and generalized estimating equation were used to analyze data.</p><p><strong>Results: </strong>There were no significant differences in patients' sociodemographic and clinical information between the intervention and control groups at baseline. The scores for depression were statistically different between the two groups (Z=-5.757, p < 0.001) at T1 and T2 (t=-7.964, p < 0.001). The scores for sleep quality were statistically different between the two groups at T1 (Z=-2.840, p = 0.005). The result of the generalized estimating equation modeling analyses indicated that interaction effects were statistically significant in depression and sleep quality scores. The intervention group showed a significantly higher rate of decrease in the depression score from T0 to T1 (95% CI: -11.227 to -7.748, p < 0.001) and T0 to T2 (95% CI: -11.683, -6.170, p < 0.001), compared with the control group; the intervention group had a greater reduction in the sleep score from T0 to T1 (95% CI: -2.502 to -0.962, p < 0.001), compared with the control group.</p><p><strong>Conclusions: </strong>MI could effectively improve depression and sleep quality in patients with early PSD. However, MI failed to improve quality of life in patients with early PSD. These findings provide a foundation for future large-scale randomized controlled trials to further evaluate the efficacy of MI in patients with early PSD.</p><p><strong>Trial registration: </strong>Retrospectively Registered, Chinese Clinical Trial Registry ( http://www.chictr.org.cn || ChiCTR2200064386|| Registration Date: 2022/10/06).</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"248"},"PeriodicalIF":3.4,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11917151/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between triglyceride-glucose index and its combination with post-stroke depression: NHANES 2005-2018.","authors":"Fengjiao Liang, Xiaoqian Shan, Xiang Chen, Banghua Yang","doi":"10.1186/s12888-025-06676-9","DOIUrl":"10.1186/s12888-025-06676-9","url":null,"abstract":"<p><strong>Background: </strong>Growing evidence indicates a link between insulin resistance and post-stroke depression (PSD). This study employed the triglyceride glucose (TyG) index as a measure of insulin resistance to investigate its relationship with PSD.</p><p><strong>Methods: </strong>This cross-sectional study utilized data from the National Health and Nutrition Examination Survey (2005-2018). PSD was assessed using data from patient health questionnaires, while the TyG index was calculated based on fasting venous blood glucose and fasting triglyceride levels. The formula used for the TyG index is ln[triglycerides (mg/dL) × fasting blood glucose (mg/dL)/2]. Participants were categorized into four groups according to the TyG index quartiles. A weighted multivariable logistic regression model was applied to examine the relationship between the TyG index and PSD.</p><p><strong>Results: </strong>A total of 1217 patients were included in the study, of which 232 were diagnosed with PSD. The TyG index was divided into quartiles (Q1-Q4) for analysis. After adjusting for potential confounders, we found a significant positive association between the highest quartile of the TyG index (Q4: ≥9.33) and PSD (OR = 2.51, 95% CI: 1.04-6.07, p = 0.041). This suggests that in the U.S. adult stroke population, individuals with higher TyG indices are more likely to experience depressive symptoms. Subgroup analysis further confirmed a stable and independent positive association between the TyG index and PSD (all trend p > 0.05).</p><p><strong>Conclusion: </strong>In this large cross-sectional study, our results suggest that among US adults who have experienced a stroke, those with higher TyG index levels are more likely to exhibit depressive symptoms. This provides a novel approach for the clinical prevention of PSD. Patients with higher TyG indices in the stroke population may require closer psychological health monitoring and timely intervention. Additionally, since the TyG index is calculated using only fasting blood glucose and triglyceride levels, it can help identify high-risk PSD patients, particularly in regions with limited healthcare resources.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"243"},"PeriodicalIF":3.4,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909874/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How rumination affect suicidal ideation: a moderated mediation model.","authors":"Tao Huang, Rong Tan, Hua Gao, Xin Tian, Kunyan Wang, Yizhi Yang, Zhenjiang Liao","doi":"10.1186/s12888-025-06682-x","DOIUrl":"10.1186/s12888-025-06682-x","url":null,"abstract":"<p><strong>Background: </strong>Rumination is regarded as a cognitive risk factor and a focal point of clinical interventions aimed at mitigating suicidal ideation. Nonetheless, the mechanisms how rumination affects suicidal ideation warrant further exploration.</p><p><strong>Methods: </strong>A cohort of 831 Chinese college students (M age = 19.30 years, SD age = 1.17; 444 females) completed a questionnaire composed of the Ruminative Responses Scale, Entrapment Scale, Mindfulness Attention Awareness Scale, and Self-Rating Idea of Suicide Scale. A moderated mediation model was used to explore the relationship between rumination, entrapment and suicidal ideation.</p><p><strong>Results: </strong>The results reveal that: (1) Rumination significantly and positively predicts suicidal ideation among college students (β = 0.26, p < 0.001); (2) Entrapment serves as a mediating role between rumination and suicidal ideation (95% CI= [0.27, 0.42]); and (3) Mindfulness moderates the impact of rumination on suicidal ideation (β = -0.09, t = -4.30, p < 0.001).</p><p><strong>Conclusions: </strong>These findings highlight entrapment as the mediator linking rumination to suicidal ideation and emphasize the potential advantages of enhancing mindfulness to alleviate suicidal ideation among Chinese college students, bearing significant implications for the prevention and intervention of suicidal ideation in this demographic.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"245"},"PeriodicalIF":3.4,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Personality perspective on depression and anxiety symptoms among Chinese adolescents and young adults: a two-sample network analysis.","authors":"Xian-Yang Wang, Zi-Wei Wang, Dong-Lei Jiang, Chang Liu, Wan-Ying Xing, Zhi-Tao Yuan, Long-Biao Cui, Sheng-Jun Wu, Lei Ren","doi":"10.1186/s12888-025-06675-w","DOIUrl":"10.1186/s12888-025-06675-w","url":null,"abstract":"<p><strong>Background: </strong>The mental health burden among adolescents has been increasing, impacting individuals even before formal diagnosis of common mental disorders. Although personality traits, as key indicators of mental health conditions, play a crucial role in the development of mental disorders, there is a gap regarding the trait-to-symptom pathways and similarities and differences between adolescents and young adults.</p><p><strong>Methods: </strong>A total of 860 adolescents and 1751 young adults participated in this study. The Chinese Big Five Personality Inventory assessed the Big Five traits, while depression and anxiety symptoms were measured using the Patient Health Questionnaire-9 and the Generalized Anxiety Disorder-7, respectively. Network analysis computed the bridging centrality of Big Five traits and elucidated trait-to-symptom pathways. Furthermore, network comparison was applied to compare network structure between adolescents and young adults.</p><p><strong>Results: </strong>In both age groups, neuroticism exhibited a transdiagnostic activating effect on depression and anxiety. Conscientiousness demonstrated the strongest protective effect against depression, whereas agreeableness was most protective against anxiety. In both samples, neuroticism primarily influenced symptoms associated with negative emotions and thoughts. Comparatively, extraversion exhibited a significant increasing protective effect against depression throughout adolescence, while neuroticism increasingly activated anxiety symptoms.</p><p><strong>Conclusions: </strong>This study highlights the potential to utilize personality traits for early detection and precise intervention in adolescent populations, providing actionable insights. By identifying the level of neuroticism, we can effectively detect high-risk adolescent individuals prior to formal diagnosis. By delineating the neuroticism-to-symptom pathways, we can implement targeted intervention on their pathological interactions.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"241"},"PeriodicalIF":3.4,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11907812/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Agreement between CES-D and CIDI-SF scales of depression among older adults: a cross-sectional comparative study based on the longitudinal aging study in India, 2017-19.","authors":"T Muhammad, Soomi Lee, Manish Kumar, T V Sekher, Mathew Varghese","doi":"10.1186/s12888-025-06671-0","DOIUrl":"10.1186/s12888-025-06671-0","url":null,"abstract":"<p><strong>Background: </strong>Understanding the differences between various instruments for assessing depression will help researchers and health practitioners to choose a more appropriate tool and develop a framework to enhance resilience to mental health problems in the older population. The current study aimed to compare the 10-item Center for Epidemiological Studies-Depression (CES-D) scale with the Composite International Diagnostic Interview-Short Form (CIDI-SF) for measuring depressive symptoms in older Indians.</p><p><strong>Methods: </strong>Data came from the first wave of the Longitudinal Aging Study in India (LASI) which was conducted during 2017-19. The final sample included 30,368 older individuals aged 60 years and above (15,824 women and 14,544 men). The level of agreement between the CES-D and CIIDI-SF instruments for depression classification was assessed using Kappa coefficients at various cut-off values. Multivariable logistic regression models were used to examine the associations between background characteristics and depressive symptoms assessed by both instruments.</p><p><strong>Results: </strong>The prevalence of depressive symptoms based on the CES-D instrument was higher than that of CIDI-SF (30.2% vs. 8.3%). The level of agreement between the CES-D and CIDI-SF for depression classification was 'none' to 'minimal' (κ = 0.04-0.24). Assuming the CIDI-SF scale as the \"gold standard\", with rising threshold values, sensitivity of the CES-D scale decreased while specificity increased. The CES-D scale yielded a sensitivity of 29-82% and specificity of 39-92% across cut-off values of 3 to 6. The Pearson correlation between the CIDI-SF and CES-D total scores was significant but weak (r =.20). Multivariable analysis showed that depressive symptoms were more prevalent among women, those with higher education, individuals living alone, those with diagnosed psychiatric disorders, and individuals with two or more chronic conditions, compared to men, those who were uneducated, those not living alone and healthier peers, when assessed using both CES-D and CIDI-SF scales. The associations of marital status, religion and wealth quintiles were significant only for depressive symptoms assessed using the CES-D scale.</p><p><strong>Conclusions: </strong>Depression cases identified by the CES-D showed poor agreement with those identified by the CIDI-SF. Therefore, the prevalence of depressive symptoms measured by the CESD is not interchangeable with that measured by the CIDI-SF. These findings suggest the importance of using both the CES-D and CIDI-SF in large population-based cohorts and surveillance surveys to obtain more accurate and nuanced understanding of depressive disorders across various subgroups of the older population.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"244"},"PeriodicalIF":3.4,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}