{"title":"在贡达尔大学综合专科医院接受精神保健服务的病人中非医疗和终生使用管制药物的流行率和预测因素:埃塞俄比亚西北部。","authors":"Tesfaye Yimer Tadesse, Zemene Demelash Kifle, Meaza Adugna, Betelhem Fisiha, Tefera Teshager, Mulugeta Ashagrie, Jibril Seid Yesuf","doi":"10.1186/s12888-025-07092-9","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Nonmedical prescription drug use (NMPDU) typically refers to the consumption of medications that have not been prescribed to the user or are used in a manner not intended by the prescriber. NMPDU may pose various health risks, including the development of abuse or dependence, particularly in individuals with mental health problems. This issue, however, has not yet been thoroughly assessed in Ethiopia.</p><p><strong>Objective: </strong>We determined the prevalence and predictors of controlled prescription drugs, non-medical, and lifetime use among patients accessing mental health services in the University of Gondar Comprehensive Specialized Hospital (UoGCSH).</p><p><strong>Methods: </strong>A hospital-based cross-sectional study was conducted at UoGCSH from June 17, 2022, to July 28, 2022, involving 146 participants. A convenience sampling technique was used to recruit the study participants, and data were collected through face-to-face interviews using a semi-structured questionnaire. The data were analyzed using the Statistical Package for Social Sciences (SPSS) version 25. Descriptive analysis was conducted to examine sociodemographic characteristics and the prevalence of Controlled Prescription Drugs (CPD) use. Multivariate logistic regression was performed to identify predictors, with statistical significance set at P ≤ 0.05.</p><p><strong>Result: </strong>Of the 146 participants, 12 (8.20%): 95% CI (3.63-12.81) reported having used CPD for non-medical purposes at some point in their lifetime. The most commonly used drugs were tramadol capsules and tramadol injections, reported by 11 participants (91.7%), and followed by amitriptyline (8.3%). The odds of CPD use were significantly higher among patients treated in the outpatient setting (AOR = 7.609, 95% CI = 1.429-40.507) compared to those treated as inpatients. Nine (75%) participants reported using CPD for non-medical purposes to relieve post-operative pain, while the remaining participants cited restlessness as the primary reason for their use.</p><p><strong>Conclusion: </strong>The results of this study revealed that tramadol, in both intravenous and oral forms, was the most frequently abused drug. It was found that patients treated in outpatient settings had greater exposure to CPD use. It is crucial to evaluate the impact of nonmedical CPD use on the health of individuals with mental health conditions and prioritize efforts to improve the quality of care for high-risk individuals.</p>","PeriodicalId":9029,"journal":{"name":"BMC Psychiatry","volume":"25 1","pages":"638"},"PeriodicalIF":3.4000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12220597/pdf/","citationCount":"0","resultStr":"{\"title\":\"Prevalence and predictors of non-medical and lifetime use of controlled drugs among patients accessing mental health services at the university of Gondar comprehensive specialized hospital: Northwest Ethiopia.\",\"authors\":\"Tesfaye Yimer Tadesse, Zemene Demelash Kifle, Meaza Adugna, Betelhem Fisiha, Tefera Teshager, Mulugeta Ashagrie, Jibril Seid Yesuf\",\"doi\":\"10.1186/s12888-025-07092-9\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Nonmedical prescription drug use (NMPDU) typically refers to the consumption of medications that have not been prescribed to the user or are used in a manner not intended by the prescriber. NMPDU may pose various health risks, including the development of abuse or dependence, particularly in individuals with mental health problems. This issue, however, has not yet been thoroughly assessed in Ethiopia.</p><p><strong>Objective: </strong>We determined the prevalence and predictors of controlled prescription drugs, non-medical, and lifetime use among patients accessing mental health services in the University of Gondar Comprehensive Specialized Hospital (UoGCSH).</p><p><strong>Methods: </strong>A hospital-based cross-sectional study was conducted at UoGCSH from June 17, 2022, to July 28, 2022, involving 146 participants. A convenience sampling technique was used to recruit the study participants, and data were collected through face-to-face interviews using a semi-structured questionnaire. The data were analyzed using the Statistical Package for Social Sciences (SPSS) version 25. Descriptive analysis was conducted to examine sociodemographic characteristics and the prevalence of Controlled Prescription Drugs (CPD) use. Multivariate logistic regression was performed to identify predictors, with statistical significance set at P ≤ 0.05.</p><p><strong>Result: </strong>Of the 146 participants, 12 (8.20%): 95% CI (3.63-12.81) reported having used CPD for non-medical purposes at some point in their lifetime. The most commonly used drugs were tramadol capsules and tramadol injections, reported by 11 participants (91.7%), and followed by amitriptyline (8.3%). The odds of CPD use were significantly higher among patients treated in the outpatient setting (AOR = 7.609, 95% CI = 1.429-40.507) compared to those treated as inpatients. Nine (75%) participants reported using CPD for non-medical purposes to relieve post-operative pain, while the remaining participants cited restlessness as the primary reason for their use.</p><p><strong>Conclusion: </strong>The results of this study revealed that tramadol, in both intravenous and oral forms, was the most frequently abused drug. It was found that patients treated in outpatient settings had greater exposure to CPD use. It is crucial to evaluate the impact of nonmedical CPD use on the health of individuals with mental health conditions and prioritize efforts to improve the quality of care for high-risk individuals.</p>\",\"PeriodicalId\":9029,\"journal\":{\"name\":\"BMC Psychiatry\",\"volume\":\"25 1\",\"pages\":\"638\"},\"PeriodicalIF\":3.4000,\"publicationDate\":\"2025-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12220597/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"BMC Psychiatry\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1186/s12888-025-07092-9\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PSYCHIATRY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMC Psychiatry","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s12888-025-07092-9","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PSYCHIATRY","Score":null,"Total":0}
引用次数: 0
摘要
背景:非医疗处方药物使用(NMPDU)通常是指未给使用者开处方或以非处方者预期的方式使用药物。NMPDU可能造成各种健康风险,包括滥用或依赖,特别是对有精神健康问题的个人。然而,这个问题在埃塞俄比亚尚未得到彻底的评估。目的:我们确定在贡达尔大学综合专科医院(UoGCSH)接受精神卫生服务的患者中受控处方药、非医疗用药和终生用药的患病率和预测因素。方法:从2022年6月17日至2022年7月28日,在UoGCSH进行了一项基于医院的横断面研究,涉及146名参与者。采用方便抽样技术招募研究参与者,采用半结构化问卷,通过面对面访谈的方式收集数据。使用社会科学统计软件包(SPSS)第25版对数据进行分析。进行描述性分析以检查社会人口学特征和管制处方药(CPD)使用的流行程度。多因素logistic回归分析预测因素,P≤0.05为有统计学意义。结果:在146名参与者中,12名(8.20%):95% CI(3.63-12.81)报告在其一生中的某个时间点使用CPD用于非医疗目的。最常用的药物是曲马多胶囊和曲马多注射剂,有11人(91.7%)报告,其次是阿米替林(8.3%)。门诊患者使用CPD的几率明显高于住院患者(AOR = 7.609, 95% CI = 1.429-40.507)。9名(75%)参与者报告使用CPD用于非医疗目的,以缓解术后疼痛,而其余参与者则将不安作为其使用CPD的主要原因。结论:本研究结果表明,曲马多,静脉注射和口服形式,是最常见的滥用药物。研究发现,在门诊治疗的患者更容易接触到CPD的使用。评估非医疗CPD使用对有精神健康状况的个体健康的影响是至关重要的,并优先努力提高对高危个体的护理质量。
Prevalence and predictors of non-medical and lifetime use of controlled drugs among patients accessing mental health services at the university of Gondar comprehensive specialized hospital: Northwest Ethiopia.
Background: Nonmedical prescription drug use (NMPDU) typically refers to the consumption of medications that have not been prescribed to the user or are used in a manner not intended by the prescriber. NMPDU may pose various health risks, including the development of abuse or dependence, particularly in individuals with mental health problems. This issue, however, has not yet been thoroughly assessed in Ethiopia.
Objective: We determined the prevalence and predictors of controlled prescription drugs, non-medical, and lifetime use among patients accessing mental health services in the University of Gondar Comprehensive Specialized Hospital (UoGCSH).
Methods: A hospital-based cross-sectional study was conducted at UoGCSH from June 17, 2022, to July 28, 2022, involving 146 participants. A convenience sampling technique was used to recruit the study participants, and data were collected through face-to-face interviews using a semi-structured questionnaire. The data were analyzed using the Statistical Package for Social Sciences (SPSS) version 25. Descriptive analysis was conducted to examine sociodemographic characteristics and the prevalence of Controlled Prescription Drugs (CPD) use. Multivariate logistic regression was performed to identify predictors, with statistical significance set at P ≤ 0.05.
Result: Of the 146 participants, 12 (8.20%): 95% CI (3.63-12.81) reported having used CPD for non-medical purposes at some point in their lifetime. The most commonly used drugs were tramadol capsules and tramadol injections, reported by 11 participants (91.7%), and followed by amitriptyline (8.3%). The odds of CPD use were significantly higher among patients treated in the outpatient setting (AOR = 7.609, 95% CI = 1.429-40.507) compared to those treated as inpatients. Nine (75%) participants reported using CPD for non-medical purposes to relieve post-operative pain, while the remaining participants cited restlessness as the primary reason for their use.
Conclusion: The results of this study revealed that tramadol, in both intravenous and oral forms, was the most frequently abused drug. It was found that patients treated in outpatient settings had greater exposure to CPD use. It is crucial to evaluate the impact of nonmedical CPD use on the health of individuals with mental health conditions and prioritize efforts to improve the quality of care for high-risk individuals.
期刊介绍:
BMC Psychiatry is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of psychiatric disorders, as well as related molecular genetics, pathophysiology, and epidemiology.