Bioresource Technology Reports最新文献

{"title":"Fungi involved in lignin degradation and humic substances formation during composting of Chinese medicinal herbal residues","authors":"Qiannuo Zeng,&nbsp;Minxin Rao,&nbsp;Jiayi Fu,&nbsp;Daiying Zhang,&nbsp;Ping Yan,&nbsp;Quan Xia,&nbsp;Chunyi Wang,&nbsp;Ying Zhang","doi":"10.1016/j.biteb.2026.102757","DOIUrl":"10.1016/j.biteb.2026.102757","url":null,"abstract":"<div><div>This study aimed to investigate the fungal taxa responsible for lignin degradation and humic substances (HS) formation, as two distinct but related key processes during the composting of Chinese medicinal herbal residues (CMHRs). Fungal strains with favorable lignin-degrading potential were isolated using the activities of three key ligninolytic enzymes (laccase, lignin peroxidase, and manganese peroxidase) as indicators. The variations of lignin-degrading enzyme activities, content of HS fractions, and fungal communities throughout the composting process, along with their interrelationships, were explored. The results showed that strain CM-d10–2, identified as <em>Pleosporales</em> sp., exhibited the highest lignin-degrading enzyme activity<em>.</em> The total activity of ligninolytic enzymes in compost attained its highest level during the thermophilic phase. The HS content accumulated continuously during the composting process and reached 110.02 g·kg⁻¹ at the maturation stage. Redundancy analysis (RDA) indicated that <em>Kodamaea</em> and <em>Melanocarpus</em> were positively correlated with the content of HS. These findings revealed key microbial groups that were associated with lignin degradation and HS formation, providing new insights for accelerating composting and improving compost quality.</div></div>","PeriodicalId":8947,"journal":{"name":"Bioresource Technology Reports","volume":"34 ","pages":"Article 102757"},"PeriodicalIF":5.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148499338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fish and fruit processing by-products in the diet of black soldier fly larvae: Implications for growth performance and fatty acid composition","authors":"Mirena Zhelezarova,&nbsp;Eliza Uzunova","doi":"10.1016/j.biteb.2026.102756","DOIUrl":"10.1016/j.biteb.2026.102756","url":null,"abstract":"<div><div>Insects are a promising protein source for aquaculture feed. The black soldier fly (<em>Hermetia illucens</em>) converts organic and industrial by-products into valuable biomass. However, the chemical composition of black soldier fly larvae (BSFL) does not meet the nutritional requirements of some aquaculture species. The aim of this study was to evaluate the feasibility of using aquaculture and fruit processing by-products as alternative substrates for BSFL and to assess their effects on growth performance and fatty acid composition relevant for rainbow trout (<em>Oncorhynchus mykiss</em>). It was hypothesized that inclusion of fish processing by-products, alone or combined with orange pulp, would modify the fatty acid profile. Three diets were tested: fish residues (F), fish residues with orange pulp (OF), and poultry feed (control). Larval growth and composition were assessed at 8 and 15 days. While the control produced higher biomass, larvae fed fish residues showed higher protein and increased EPA and DHA.</div></div>","PeriodicalId":8947,"journal":{"name":"Bioresource Technology Reports","volume":"34 ","pages":"Article 102756"},"PeriodicalIF":5.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148476621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Techno-economic analysis of a photobiorefinery for the production of polyhydroxyalkanoates from food waste","authors":"Zoi Stavropoulou,&nbsp;Nikiforos Misailidis,&nbsp;Vassilis Parisis,&nbsp;Demetri Petrides,&nbsp;Michael C. Georgiadis","doi":"10.1016/j.biteb.2026.102843","DOIUrl":"10.1016/j.biteb.2026.102843","url":null,"abstract":"<div><div>This study presents the design and economic evaluation of a photobiorefinery using a mixed culture of purple phototrophic bacteria for the production of polyhydroxyalkanoates (PHAs) from food waste. The process was simulated using SuperPro Designer™. Two downstream processes were assessed: solvent extraction from dry biomass and solvent extraction from wet slurry. The facility had a treatment capacity of 102.4 kt/y and an annual PHA production of 5000 t. Biohydrogen was produced as a by-product at 322 t/y. The NPV was estimated at $38.6 M and $51.3 M for dry and wet extraction. The PHA minimum selling price was 4.81 $/kg and 4.41 $/kg, respectively, with wet extraction significantly improving profitability. However, both designs proved less cost-competitive compared to non-photosynthetic PHA production in the literature, mainly due to low volumetric productivity and high PHA recovery costs. A PHA price below 4 $/kg can be achieved by increasing the PHA yield of photofermentation.</div></div>","PeriodicalId":8947,"journal":{"name":"Bioresource Technology Reports","volume":"34 ","pages":"Article 102843"},"PeriodicalIF":5.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148476920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of thermal pretreatment on characteristic and anaerobic digestion of Sunflower meal","authors":"Asad Ayub Rajput,&nbsp;Zeshan,&nbsp;Muhammad Raheel Bawani,&nbsp;Saleem Raza Chalgri","doi":"10.1016/j.biteb.2026.102830","DOIUrl":"10.1016/j.biteb.2026.102830","url":null,"abstract":"<div><div>Lignocellulosic nature of sunflower meal (SFM) is the main hindrance in its anaerobic digestion (AD). Therefore, the focus of the present study is to assess the influence of thermal pretreatment (TPT) on chemical and structural changes as well as biogas production of SFM. Therefore, TPT of SFM was performed at temperatures 120, 140, 160 and 180 °C and compared with untreated SFM. Reactor fed with SFM-180 °C showed the highest biogas yield of 873 NmL/gVS which is 29% higher as compared to untreated SFM. Images from scanning electron microscope (SEM) revealed the appearances of new surfaces in pretreated SFM at 180 °C as compared to raw SFM. Fourier transformation infrared spectroscopy (FTIR) results showed changes in chemical bonds due to the TPT of SFM at 180 °C. The modified Gompertz model (MGM) was best fitted on the TPT data of SFM and showed a shorter lag phase time as the TPT temperature increased. Changes in the lignocellulosic structure were the main reasons for optimizing the anaerobic process.</div></div>","PeriodicalId":8947,"journal":{"name":"Bioresource Technology Reports","volume":"34 ","pages":"Article 102830"},"PeriodicalIF":5.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148476982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thermophilic and mesophilic two-phase co-digestion of the organic fraction of municipal solid waste with sewage sludge and equine manure","authors":"Laura André ,&nbsp;Joel Awinzure Agumah ,&nbsp;Flavien Picard ,&nbsp;Xiaojun Liu ,&nbsp;Thomas Moreau ,&nbsp;Alain Magis ,&nbsp;Olivier Bernat ,&nbsp;Nabil Mabrouk ,&nbsp;Florian Routhier ,&nbsp;Antoine Brunet ,&nbsp;Patrick Billette ,&nbsp;André Pauss ,&nbsp;Thierry Ribeiro","doi":"10.1016/j.biteb.2026.102614","DOIUrl":"10.1016/j.biteb.2026.102614","url":null,"abstract":"<div><div>This study aimed to evaluate the feasibility of treating a unique mixture of substrates through two-phase anaerobic digestion at reduced retention times. Sewage sludge was co-digested with organic fraction of municipal solid waste and straw-rich equine manure in 20 L laboratory-scale anaerobic digesters operated under thermophilic and mesophilic conditions. Despite short hydraulic retention times (HRT) of 2 d in the thermophilic reactor followed by 12 or 15 d in the mesophilic reactor, no apparent process inhibition was observed. The system operated under high organic loading rates in the mesophilic phase (6.7 and 5.3 g_VS·L⁻¹·d⁻¹). Under these conditions, methane yields of approximately 235–245 NL_CH₄·kg_VS⁻¹ were achieved, corresponding to nearly 80% of the biochemical methane potential of the co-digested substrate (301 NL_CH₄·kg _VS⁻¹). The methanogenic reactor also showed good resilience, with gas production improving over the course of the experiment, with the volumetric methane production rate reaching 1.60 NL_CH₄·L⁻¹ reactor d⁻¹ at an HRT of 12 days and 1.27 NL_CH₄·L⁻¹ reactor·d⁻¹) at 15 days. The addition of strawed equine manure improved the C/N ratio and avoided potential inhibition by ammonia, reducing ammoniacal nitrogen concentrations from 4.7 g·L⁻¹ to 2.6 g·L⁻¹. The laboratory results indicated a strong potential for scale-up, because the system exhibited consistent performance and adaptability. These results were subsequently used in the design of a pilot plant processing 2–3 t·d⁻¹, which is currently operational.</div></div>","PeriodicalId":8947,"journal":{"name":"Bioresource Technology Reports","volume":"34 ","pages":"Article 102614"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146135747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Environmental optimization of dietary fiber extraction from spent coffee grounds derived from coffee shop waste: A life cycle assessment approach","authors":"Sarha Lucia Murillo-Franco,&nbsp;Henrique Maziero Fogarin,&nbsp;Matheus Costa Monteiro dos Santos,&nbsp;Annamaria Acampora,&nbsp;Lucia Acampora,&nbsp;Antonella Petrillo,&nbsp;Kelly Johana Dussán","doi":"10.1016/j.biteb.2026.102785","DOIUrl":"10.1016/j.biteb.2026.102785","url":null,"abstract":"<div><div>Spent coffee grounds (SCGs) are an abundant source of organic waste with significant potential for valorization, including dietary fiber extraction. The objective of this study was to evaluate and optimize the environmental performance of producing dietary fiber from SCGs using diluted acid hydrolysis, emphasizing the influence of key process variables on environmental impacts. In this sense, a life cycle assessment (LCA) was conducted according to <em>ISO 14040</em> guidelines using a gate-to-gate approach with inventories based on material and energy balances derived from <em>Aspen Plus V.12</em> from experimental results. A two-factor interaction (2FI) statistical model was used to identify significant process variables during the hydrolysis stage and was optimized using a genetic algorithm (GA). The results revealed that the fiber purification and solvent recovery stages had the highest environmental impact across all evaluated scenarios. Climate Change (CC) associated with producing dietary fiber from SCGs was comparable to emissions from alternative valorization routes studied in the literature. Furthermore, human toxicity (HT) impacts were equivalent to or lower than those of dietary fibers derived from other agro-industrial residues. Terrestrial Acidification (TA) impacts were not significantly affected by acid concentration. The 2FI model identified the solid:liquid ratio as the critical factor affecting environmental outcomes. Optimization showed that the best environmental performance is achieved at high temperatures and low solid-to-liquid ratios. This study demonstrated that combining the life cycle assessment method, statistical modeling, and artificial intelligence is an effective strategy for optimizing SCG valorization in fiber production in environmental terms.</div></div>","PeriodicalId":8947,"journal":{"name":"Bioresource Technology Reports","volume":"34 ","pages":"Article 102785"},"PeriodicalIF":5.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148477103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative evaluation of green extraction techniques for flavonoid recovery from peanut shells: Kinetic modeling, bioactivity assessment, and efficiency enhancement via sequential cellulase–ultrasound extraction","authors":"Chau B. Tran,&nbsp;Nhat Tan Nguyen,&nbsp;Thi Thao Vy Nguyen,&nbsp;Nguyen Minh Khanh Pham,&nbsp;Huynh Thuy Truc Tran,&nbsp;Nhut Hao Huynh,&nbsp;Tuyet Nhung Tran,&nbsp;Dieu-Hien Truong,&nbsp;Colin J. Barrow,&nbsp;Hoang Chinh Nguyen","doi":"10.1016/j.biteb.2026.102760","DOIUrl":"10.1016/j.biteb.2026.102760","url":null,"abstract":"<div><div>Peanut shells are a promising source of flavonoids; however, systematic comparative studies on extraction efficiency and the bioactivities of the resulting extracts remain limited. This study proposed that sequential cellulase-ultrasound extraction (SCUE) could enhance flavonoid recovery and bioactivity compared with individual green extraction methods and conventional techniques. Accordingly, cellulase-assisted extraction, ultrasound-assisted extraction, and SCUE were evaluated alongside Soxhlet extraction and hot ethanol extraction. Under optimal conditions (2% cellulase, 40% ultrasound amplitude, and 280 min extraction time), SCUE achieved the highest total flavonoid content (54.58 mg QE/g), quercetin (24.32 μg/g), and luteolin (148.61 μg/g). Peleg's model adequately described the extraction kinetics and confirmed the superior efficiency of SCUE. The SCUE extract also exhibited the strongest DPPH and acetylcholinesterase (AChE) inhibitory activities, with IC₅₀ values of 42.76 μg/mL and 66.27 μg/mL, respectively. These findings highlight SCUE as an effective green strategy for valorizing peanut shell waste into flavonoid-rich extracts with functional potential.</div></div>","PeriodicalId":8947,"journal":{"name":"Bioresource Technology Reports","volume":"34 ","pages":"Article 102760"},"PeriodicalIF":5.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148476622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis of two biorefineries for high-purity phycocyanin, biocrude and biogas production from Arthrospira platensis: a life cycle assessment and simulation approach","authors":"Jennifer Sánchez-Laso,&nbsp;Juan J. Espada,&nbsp;Rosalía Rodríguez,&nbsp;Noelia García,&nbsp;Alejandro Piera,&nbsp;Gemma Vicente,&nbsp;Luis Fernando Bautista","doi":"10.1016/j.biteb.2026.102851","DOIUrl":"10.1016/j.biteb.2026.102851","url":null,"abstract":"<div><div>This study evaluates the environmental performance of a cyanobacterial biorefinery for producing high-purity phycocyanin (PC) coupled with the valorisation of waste biomass (WB) via either hydrothermal liquefaction (HTL, scenario 1 A) or anaerobic digestion (AD, scenario 1B). Both pathways are compatible with cyanobacterial WB but differ in energy demand, chemical requirements, and downstream processing. Life Cycle Assessment (LCA) was conducted using inventory data from process simulation and experimental extraction data. LCA results showed that PC extraction and purification were the most important contributors across all impact categories due to the large consumption of salts and ionic liquid (IL), respectively. Regarding biomass valorisation, AD presented advantages over HTL due to lower chemical and energy requirements. Based on these results, the influence of IL recovery was studied, and scenario 2 (IL recovery 90% + AD) was constructed and analysed from an LCA perspective. The comparison of LCA results for the analysed scenarios showed that increasing IL recovery by 15% (scenario 2) led to impact reductions up to 46% in the extraction step, achieving reductions up to 37% and 12% in the overall process compared to scenarios 1 A and 1B, respectively. Furthermore, scenario 2 yielded a carbon footprint value of 52.07 kg CO eq./kg of dried biomass, within the range reported in the literature for other PC production biorefineries. These results demonstrate the environmental feasibility of integrating high-purity PC production within a cyanobacterial framework, identify AD as the more environmentally favourable residue valorisation pathway and highlight the importance of solvent recovery efficiency.</div></div>","PeriodicalId":8947,"journal":{"name":"Bioresource Technology Reports","volume":"34 ","pages":"Article 102851"},"PeriodicalIF":5.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148476917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sugars influence substrate temperature and larval growth in black soldier fly bioconversion","authors":"A. Fuhrmann,&nbsp;M. Gold,&nbsp;Y. Bi,&nbsp;P. Azzari,&nbsp;M.J. Zorrilla,&nbsp;N. Puniamoorthy,&nbsp;A. Mathys","doi":"10.1016/j.biteb.2026.102815","DOIUrl":"10.1016/j.biteb.2026.102815","url":null,"abstract":"<div><div>In black soldier fly larvae bioconversion, organic waste is upcycled into animal feed and fertilizer. Substrate temperature is a key factor for climate control and larval growth, and excessive heat can interrupt operation, yet its drivers are understudied. Digestible carbohydrates, a variable and abundant component of organic waste, could be a critical driver of temperature variation. Therefore, in this study, we investigated whether different digestible carbohydrates in organic waste affect temperature and larval growth. The okara-based substrate was supplemented with carbohydrates (20% based on dry matter). In a 7-day controlled feeding trial with industrial crates (60 cm × 40 cm crates, 8640 larvae each), we determined whether the sugar type (isomaltulose versus sucrose, i.e. high versus low digestion rate) and availability (day 0, day 3) affected larval dry mass, substrate temperature, metabolites, and pH as well as CO₂, and NH₃ emissions. We found that sugars strongly altered substrate temperature in a time-dependent manner. Sucrose addition on day 0 produced higher temperatures (mean increase: 2.1 °C, max.: 7.9 °C) and resulted in a lower final larval mass (∼ 20%) compared to sucrose addition on day 3. Isomaltulose addition resulted in a lower mean (0.4 °C versus sucrose) but highest peak (51.3 °C) temperature. pH and NH₃ concentration dropped after sucrose addition. Trends in metabolites suggested O₂-dependent metabolic shifts during early bioconversion. These results showed that the timing of sugar supply can shape thermal dynamics and larval yield, with implications for optimizing temperature control and efficiency in black soldier fly larvae bioconversion.</div></div>","PeriodicalId":8947,"journal":{"name":"Bioresource Technology Reports","volume":"34 ","pages":"Article 102815"},"PeriodicalIF":5.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148476993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lepidocrocite-enhanced microbial removal of selenite under long-term anaerobic conditions: Biological responses and electron transfer","authors":"Yue-gan Liang,&nbsp;Ming-qiang Xia,&nbsp;Yu-chun Tao,&nbsp;Yong Wu","doi":"10.1016/j.biteb.2026.102839","DOIUrl":"10.1016/j.biteb.2026.102839","url":null,"abstract":"<div><div>Wastewater containing selenite poses a significant threat to aquatic ecosystems and human health; however, the rate of microbial reduction is often limited by low electron transfer efficiency. This study aims to enhance microbial selenium removal by using lepidocrocite to facilitate electron transfer and elucidates the underlying enhancement mechanism through selenite reductase activity, metagenomics, and electrochemical analyses under long-term anaerobic conditions. The results showed that lepidocrocite enhanced selenite removal over 120 days of operation, significantly reducing the average effluent concentration from 0.92 mg/L in the control group to 0.53 mg/L and increasing the removal rate. It also promoted the transformation of elemental selenium into selenide. This enhancement resulted from lepidocrocite facilitating electron transfer and triggering biological responses such as increased extracellular polymeric substance (EPS) secretion, elevated selenite reductase activity, and enrichment of functional microorganism. Specifically, lepidocrocite markedly increased the protein and polysaccharide contents of EPS by 261% and 148%, respectively. Additionally, lepidocrocite significantly enhanced the activities of sulfite reductase, glutathione reductase, periplasmic fumarate reductase, and nitrite reductase by 202.7%, 63.1%, 44.2%, and 175%, respectively. Furthermore, lepidocrocite improved the abundance of selenite-reducing bacteria (<em>Zoogloea</em>, <em>Alicycliphilus</em>, <em>Mesotoga</em>) and electroactive bacteria (<em>Azoarcus</em>), along with upregulation of functional genes involved in electron transport, selenite reduction, and lactic acid metabolism. Electrochemical and X-ray photoelectron spectroscopy analyses also indirectly demonstrated that lepidocrocite accelerated electron transfer via an electron-shuttling mechanism and the conductive mediation mechanism of its biogenic product, magnetite. These findings provide new insights for improving the bioremediation efficiency of selenite.</div></div>","PeriodicalId":8947,"journal":{"name":"Bioresource Technology Reports","volume":"34 ","pages":"Article 102839"},"PeriodicalIF":5.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148476995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}