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Retraction: Resveratrol enhances matrix biosynthesis of nucleus pulposus cells through activating autophagy via the PI3K/Akt pathway under oxidative damage. 撤回：在氧化损伤条件下，白藜芦醇通过PI3K/Akt途径激活自噬，从而增强髓核细胞的基质生物合成。
IF 3.8 3区 生物学
Bioscience Reports Pub Date : 2024-08-28 DOI: 10.1042/BSR-2018-0544_RET
{"title":"Retraction: Resveratrol enhances matrix biosynthesis of nucleus pulposus cells through activating autophagy via the PI3K/Akt pathway under oxidative damage.","authors":"","doi":"10.1042/BSR-2018-0544_RET","DOIUrl":"10.1042/BSR-2018-0544_RET","url":null,"abstract":"","PeriodicalId":8926,"journal":{"name":"Bioscience Reports","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11345666/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142016274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial Note: Bioactive lipids in intervertebral disc (IVD) degeneration and its therapeutic implications. 编者按：椎间盘 (IVD) 退化中的生物活性脂质及其治疗意义。
IF 3.8 3区 生物学
Bioscience Reports Pub Date : 2024-08-28 DOI: 10.1042/BSR-2019-2117_EDN
{"title":"Editorial Note: Bioactive lipids in intervertebral disc (IVD) degeneration and its therapeutic implications.","authors":"","doi":"10.1042/BSR-2019-2117_EDN","DOIUrl":"https://doi.org/10.1042/BSR-2019-2117_EDN","url":null,"abstract":"","PeriodicalId":8926,"journal":{"name":"Bioscience Reports","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142085921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retraction: Hyper-osmolarity environment-induced oxidative stress injury promotes nucleus pulposus cell senescence in vitro. 撤回：高渗环境诱导的氧化应激损伤促进体外髓核细胞衰老
IF 3.8 3区 生物学
Bioscience Reports Pub Date : 2024-08-28 DOI: 10.1042/BSR-2019-1711_RET
{"title":"Retraction: Hyper-osmolarity environment-induced oxidative stress injury promotes nucleus pulposus cell senescence in vitro.","authors":"","doi":"10.1042/BSR-2019-1711_RET","DOIUrl":"10.1042/BSR-2019-1711_RET","url":null,"abstract":"","PeriodicalId":8926,"journal":{"name":"Bioscience Reports","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11345660/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142016261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retraction: Responses of apoptosis and matrix metabolism of annulus fibrosus cells to different magnitudes of mechanical tension in vitro. 撤回：环状纤维肌细胞凋亡和基质代谢对体外不同程度机械拉力的反应
IF 3.8 3区 生物学
Bioscience Reports Pub Date : 2024-08-28 DOI: 10.1042/BSR-2018-2375_RET
{"title":"Retraction: Responses of apoptosis and matrix metabolism of annulus fibrosus cells to different magnitudes of mechanical tension in vitro.","authors":"","doi":"10.1042/BSR-2018-2375_RET","DOIUrl":"10.1042/BSR-2018-2375_RET","url":null,"abstract":"","PeriodicalId":8926,"journal":{"name":"Bioscience Reports","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11345782/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142016270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clo-miR-14: A medicinally valued spice-derived miRNA with Therapeutic Implications in Rheumatoid Arthritis. Clo-miR-14：一种具有药用价值的香料提取 miRNA，对类风湿性关节炎具有治疗意义。
IF 3.8 3区 生物学
Bioscience Reports Pub Date : 2024-08-28 DOI: 10.1042/BSR20240311
Ashish Sarkar, Mohd Saquib, Debolina Chakraborty, Sonia Mann, Swati Malik, Prachi Agnihotri, Lovely Joshi, Rajesh Malhotra, Sagarika Biswas
{"title":"Clo-miR-14: A medicinally valued spice-derived miRNA with Therapeutic Implications in Rheumatoid Arthritis.","authors":"Ashish Sarkar, Mohd Saquib, Debolina Chakraborty, Sonia Mann, Swati Malik, Prachi Agnihotri, Lovely Joshi, Rajesh Malhotra, Sagarika Biswas","doi":"10.1042/BSR20240311","DOIUrl":"https://doi.org/10.1042/BSR20240311","url":null,"abstract":"<p><p>Plant microRNAs (miRNA) are regularly consumed orally along with diet, gaining attention for their RNA-based drug potential because of their ability to regulate mammalian gene expression specifically at the post-transcriptional level. Medicinally valued plants are well known for their anti-inflammatory property; however, the contribution of their miRNA in managing inflammation has been less studied. We investigated miRNA from four medicinally valued regularly consumed spices, and validated one of the most potential miRNA \"Clo-miR-14\" for its thermal stability, and absorption in the plasma samples of RA patient's by RT-PCR. In-vitro and in-vivo studies were performed to investigate the effect of Clo-miR-14 in ameliorating Rheumatoid Arthritis (RA) like symptoms. Our results suggest that \"Clo-miR-14,\" an exogenous miRNA present in Curcuma longa, absorbed through regular diet, has robust thermal stability at 100℃ in humans. It significantly reduced pro-inflammatory cytokines (TNF, IL-1β, IL-6) and RA-like symptoms, suggesting that plant-based miRNA could be a promising candidate as an RNA-based drug for RA pathogenesis.</p>","PeriodicalId":8926,"journal":{"name":"Bioscience Reports","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142079068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retraction: Osteogenic protein-1 alleviates high glucose microenvironment-caused degenerative changes in nucleus pulposus cells. 撤回：成骨蛋白-1能缓解高糖微环境导致的髓核细胞退行性变化
IF 3.8 3区 生物学
Bioscience Reports Pub Date : 2024-08-28 DOI: 10.1042/BSR-2019-0170_RET
{"title":"Retraction: Osteogenic protein-1 alleviates high glucose microenvironment-caused degenerative changes in nucleus pulposus cells.","authors":"","doi":"10.1042/BSR-2019-0170_RET","DOIUrl":"10.1042/BSR-2019-0170_RET","url":null,"abstract":"","PeriodicalId":8926,"journal":{"name":"Bioscience Reports","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11345662/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142016266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retraction: Resveratrol inhibits IL-1β-mediated nucleus pulposus cell apoptosis through regulating the PI3K/Akt pathway. 撤回：白藜芦醇通过调节 PI3K/Akt 通路抑制 IL-1β 介导的髓核细胞凋亡
IF 3.8 3区 生物学
Bioscience Reports Pub Date : 2024-08-28 DOI: 10.1042/BSR-2019-0043_RET
{"title":"Retraction: Resveratrol inhibits IL-1β-mediated nucleus pulposus cell apoptosis through regulating the PI3K/Akt pathway.","authors":"","doi":"10.1042/BSR-2019-0043_RET","DOIUrl":"10.1042/BSR-2019-0043_RET","url":null,"abstract":"","PeriodicalId":8926,"journal":{"name":"Bioscience Reports","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11345778/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142016276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retraction: Transforming growth factor-β1-regulated Fas/FasL pathway activation suppresses nucleus pulposus cell apoptosis in an inflammatory environment. 撤回：转化生长因子-β1调节的Fas/FasL通路激活可抑制炎症环境中髓核细胞的凋亡。
IF 3.8 3区 生物学
Bioscience Reports Pub Date : 2024-08-28 DOI: 10.1042/BSR-2019-1726_RET
{"title":"Retraction: Transforming growth factor-β1-regulated Fas/FasL pathway activation suppresses nucleus pulposus cell apoptosis in an inflammatory environment.","authors":"","doi":"10.1042/BSR-2019-1726_RET","DOIUrl":"10.1042/BSR-2019-1726_RET","url":null,"abstract":"","PeriodicalId":8926,"journal":{"name":"Bioscience Reports","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11345668/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142016280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retraction: Nucleus pulposus cell senescence is alleviated by resveratrol through regulating the ROS/NF-κB pathway under high-magnitude compression. 撤回：在高强度挤压下，白藜芦醇可通过调节 ROS/NF-κB 通路缓解髓核细胞衰老。
IF 3.8 3区 生物学
Bioscience Reports Pub Date : 2024-08-28 DOI: 10.1042/BSR-2018-0670_RET
{"title":"Retraction: Nucleus pulposus cell senescence is alleviated by resveratrol through regulating the ROS/NF-κB pathway under high-magnitude compression.","authors":"","doi":"10.1042/BSR-2018-0670_RET","DOIUrl":"10.1042/BSR-2018-0670_RET","url":null,"abstract":"","PeriodicalId":8926,"journal":{"name":"Bioscience Reports","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11345779/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142016265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retraction: Resveratrol attenuates high glucose-induced nucleus pulposus cell apoptosis and senescence through activating the ROS-mediated PI3K/Akt pathway. 撤回：白藜芦醇通过激活 ROS 介导的 PI3K/Akt 通路减轻高糖诱导的髓核细胞凋亡和衰老。
IF 3.8 3区 生物学
Bioscience Reports Pub Date : 2024-08-28 DOI: 10.1042/BSR-2017-1454_RET
{"title":"Retraction: Resveratrol attenuates high glucose-induced nucleus pulposus cell apoptosis and senescence through activating the ROS-mediated PI3K/Akt pathway.","authors":"","doi":"10.1042/BSR-2017-1454_RET","DOIUrl":"10.1042/BSR-2017-1454_RET","url":null,"abstract":"","PeriodicalId":8926,"journal":{"name":"Bioscience Reports","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11345785/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142016271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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