Biopolymers最新文献_第7页

Solvent stabilizing effects on the order–disorder transition of schizophyllan in aqueous mixtures of carboxylic acids 溶剂对羧酸水性混合物中五味子苷阶-阶转变的稳定作用。

IF 3.2 4区生物学

Biopolymers Pub Date : 2024-05-31 DOI: 10.1002/bip.23604

Kazuto Yoshiba, Yota Yasuda, Mana Sato, Yasuhiro Matsuda

{"title":"Solvent stabilizing effects on the order–disorder transition of schizophyllan in aqueous mixtures of carboxylic acids","authors":"Kazuto Yoshiba, Yota Yasuda, Mana Sato, Yasuhiro Matsuda","doi":"10.1002/bip.23604","DOIUrl":"10.1002/bip.23604","url":null,"abstract":"Schizophyllan is a triple helical β-1,3-D-glucan, and shows the cooperative order–disorder transition in the aqueous solution at the triple helix state. In this paper, the solvent stabilizing effects of two carboxylic acids, acetic acid and citric acid, on the cooperative order–disorder transition of aqueous schizophyllan solution were investigated from DSC and SEC-MALS measurements. The transition temperature (Tr) was shifted to higher temperature with increasing the molar fraction of carboxylic acid in the mixture (x). The transition enthalpy (ΔHr) was increased with increasing x. These solvent stabilizing effects indicate that these carboxylic acid molecules were selectively associated with the branched side chains of schizophyllan to stabilize the ordered state. The composition dependencies of Tr and ΔHr were analyzed by the linear cooperative transition theory to estimate the association parameters between the side chains and carboxylic acid. The theoretical parameters obtained were compared with those for the other active substances for the transition to discuss the molecular interactions between the triple helix and carboxylic acid.","PeriodicalId":8866,"journal":{"name":"Biopolymers","volume":"115 5","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141178603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Starch-chitosan blends: A comprehensive review on the preparation, physicochemical properties and applications 淀粉壳聚糖混合物：淀粉-壳聚糖混合物：关于制备、理化特性和应用的全面综述。

IF 3.2 4区生物学

Biopolymers Pub Date : 2024-05-30 DOI: 10.1002/bip.23602

Wan Roslina Wan Yusof, Sumiyyah Sabar, Mohd Alhafiizh Zailani

{"title":"Starch-chitosan blends: A comprehensive review on the preparation, physicochemical properties and applications","authors":"Wan Roslina Wan Yusof, Sumiyyah Sabar, Mohd Alhafiizh Zailani","doi":"10.1002/bip.23602","DOIUrl":"10.1002/bip.23602","url":null,"abstract":"Starch and chitosan, polysaccharides derived from natural sources, have significant potential across various domains. Starch is extracted from starch-bearing plants, such as potatoes, whereas chitosan is obtained from the exoskeletons of marine animals, fungi and insects. However, the original forms of starch and chitosan have several limitations, such as low solubility and weak mechanical strength. Interestingly, the combined effects of starch and chitosan resulted in the development of starch-chitosan blends with markedly improved functional properties. These blends demonstrated high tensile strength, improved hydrophilicity and increased adsorption capacity. Furthermore, modification of starch-chitosan blends by techniques such as crosslinking and incorporation of other functional materials contributes to diverse characteristics and functionalities. This review addresses a crucial gap in the literature by providing an overview and up-to-date analysis of starch-chitosan blends. The preparation methods and functional properties of these blends in various forms, such as films, beads and hydrogels, have been extensively discussed. Emphasis is placed on the versatile applications of these blends in research, development and industries such as pharmaceuticals, wastewater treatment, agriculture and food technology. This review aims to provide an insightful overview of starch-chitosan blends and stimulate broader interdisciplinary research interests. By providing concluding insights and prospects, this review highlights the potential for further exploration of the impact of starch-chitosan blends on consumers and the environment.","PeriodicalId":8866,"journal":{"name":"Biopolymers","volume":"115 5","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141178604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact and torsional behavior of additive layer-manufactured biopolymer: An advancement for orthopedic applications 添加层制造的生物聚合物的冲击和扭转行为：骨科应用的进步。

IF 3.2 4区生物学

Biopolymers Pub Date : 2024-05-29 DOI: 10.1002/bip.23600

Shrutika Sharma, Deepa Mudgal, Vishal Gupta

{"title":"Impact and torsional behavior of additive layer-manufactured biopolymer: An advancement for orthopedic applications","authors":"Shrutika Sharma, Deepa Mudgal, Vishal Gupta","doi":"10.1002/bip.23600","DOIUrl":"10.1002/bip.23600","url":null,"abstract":"Distal ulna locking bone plates (DLBPs) are commonly employed in the treatment of distal ulna fractures. However, commercially available metallic bone plates experience stress shielding and lack corrosion resistance. Poly lactic acid (PLA) is highly favored biopolymer due to its biocompatible and bioabsorbable nature with human tissues. The use of additive layer manufacturing (ALM) is gaining attention for creating customized implants with intricate structures tailored to patient autonomy. ALM-based PLA bone plates must provide high resistance against impact and torsional forces, necessitating the adjustment of printing process parameters. This study focuses on examining the influence of key printing parameters, on the impact strength and torque-withstanding capability of DLBPs. Experimental results, along with microscopic images, reveal that an increase in infill density (IF) and wall thickness imparts strong resistance to layers against crack propagation under impact and torsional loads. On the contrary, an increase in layer height and printing speed leads to delamination and early fracture of layers during impact and torsional testing. IF significantly contributes to improving the impact strength and torque-withstanding capability of DLBPs by 70.53% and 80.65%, respectively. The study highlights the potential of the ALM technique in developing DLBPs with sufficient mechanical strength for biomedical applications.","PeriodicalId":8866,"journal":{"name":"Biopolymers","volume":"115 5","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141161295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Starch-based films affected by the addition of collagen from Prochilodus magdalenae residues and HPMC: Application in Andean blackberry (Rubus glaucus Benth) coatings 淀粉基薄膜在添加了来自大肠杆菌（Prochilodus magdalenae）残留物的胶原蛋白和 HPMC 后的影响：在安第斯黑莓（Rubus glaucus Benth）涂层中的应用。

IF 3.2 4区生物学

Biopolymers Pub Date : 2024-05-23 DOI: 10.1002/bip.23601

Vanessa Acevedo-Puello, Paula Gómez-Contreras, Rodrigo Ortega-Toro

{"title":"Starch-based films affected by the addition of collagen from Prochilodus magdalenae residues and HPMC: Application in Andean blackberry (Rubus glaucus Benth) coatings","authors":"Vanessa Acevedo-Puello, Paula Gómez-Contreras, Rodrigo Ortega-Toro","doi":"10.1002/bip.23601","DOIUrl":"10.1002/bip.23601","url":null,"abstract":"Starch-based films offer the advantages of biodegradability, edibility, barrier properties, flexibility, and adaptability. This study compared the physicochemical properties of starch-based films by adding raw fish collagen and hydroxypropylmethylcellulose (HPMC). The tensile properties were evaluated, and the interaction with water was analyzed. Barrier properties, such as water vapor and oxygen permeability, were examined, and optical properties, such as gloss and good internal transmittance, were evaluated. The films were evaluated as coatings on Andean blackberries (Rubus glaucus Benth) for 2 weeks at 85% RH and 25°C. The results showed that the inclusion of collagen caused a reduction in the tensile strength and elastic modulus of the films. Also, the formulation with the highest collagen concentration (F7) exhibited the lowest weight loss and water vapor permeability, also it had the highest collagen concentration and showed the highest reduction in Xw and WAC, with values of 0.048 and 0.65 g water/g dry film, respectively. According to analyzing the optical properties, F1 presented the highest bright-ness and transmittance values, with 18GU and 82 nm values, respectively. In general, the films and coatings are alternatives to traditional packaging materials to prolong the shelf life of these fruits.","PeriodicalId":8866,"journal":{"name":"Biopolymers","volume":"115 5","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141080416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fabrication of porous poly(L-lactide-co-ε-caprolactone) micropowder for microbubble effect and ultrasound-mediated drug delivery 制备多孔聚（L-乳酸-共ε-己内酯）微粉，用于微泡效应和超声介导的药物输送

IF 3.2 4区生物学

Biopolymers Pub Date : 2024-05-16 DOI: 10.1002/bip.23587

Jin Ik Lim

{"title":"Fabrication of porous poly(L-lactide-co-ε-caprolactone) micropowder for microbubble effect and ultrasound-mediated drug delivery","authors":"Jin Ik Lim","doi":"10.1002/bip.23587","DOIUrl":"10.1002/bip.23587","url":null,"abstract":"Biodegradable elastic poly(L-lactide-co-ε-caprolactone) (PLCL) copolymer (50:50, lactide:caprolactone molar ratio) was synthesized and porous PLCL micropowders was fabricated by a simple method involving rapid cooling of 0.1, 0.5, and 1% (wt/vol) PLCL/dioxane spray into liquid nitrogen. The physicochemical properties of the porous PLCL micropowders were examined by measuring their pore size, pore morphology, and microbead size using a scanning electron microscopy (SEM) and dye and temozolomide (TMZ)-release testing under ultrasound. Human U-87MG, glioblastoma (GBM) cell culture tests were performed to evaluate cell cytotoxicity by released drug from PLCL micropowders. In this study, the porous PLCL micropowders prepared from 1 wt%/vol% PLCL solutions showed a highly porous structure, satisfactory mechanical properties, and optimal drug release efficiency compared with those produced from 0.1 or 0.5 wt%/vol% solutions. The results of the accumulated release test with the results of the absorbance of the dye initially applied, it was confirmed that more than 80% of the added dye was trapped inside the micropowder, and clearly GBM cytotoxicity effect could be observed by the released TMZ. The drug release system using micropowders and ultrasound can be applied as a drug supply system for various diseases such as brain tumors with low drug permeability.","PeriodicalId":8866,"journal":{"name":"Biopolymers","volume":"115 5","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140943885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extraction of cellulose from halophytic plants for the synthesis of a novel biocomposite 从盐生植物中提取纤维素，用于合成新型生物复合材料。

IF 3.2 4区生物学

Biopolymers Pub Date : 2024-05-15 DOI: 10.1002/bip.23586

Uroosa Ejaz, Yusra Shafquat, Muhammad Sohail, Aizaz Ahmed Shaikh, Muhammad Daniyal Arain, Tehmees Ahmed, Abdullah K. Alanazi

{"title":"Extraction of cellulose from halophytic plants for the synthesis of a novel biocomposite","authors":"Uroosa Ejaz, Yusra Shafquat, Muhammad Sohail, Aizaz Ahmed Shaikh, Muhammad Daniyal Arain, Tehmees Ahmed, Abdullah K. Alanazi","doi":"10.1002/bip.23586","DOIUrl":"10.1002/bip.23586","url":null,"abstract":"Cellulose nanofibers, a sustainable and promising material with widespread applications, exhibit appreciable strength and excellent mechanical and physicochemical properties. The preparation of cellulosic nanofibers from food or agricultural residue is not sustainable. Therefore, this study was designed to use three halophytic plants (Cressa cretica, Phragmites karka, and Suaeda fruticosa) to extract cellulose for the subsequent conversion to cellulosic nanofibers composites. The other extracted biomass components including lignin, hemicellulose, and pectin were also utilized to obtain industrially valuable enzymes. The maximum pectinase (31.56 IU mL−1), xylanase (35.21 IU mL−1), and laccase (15.89 IU mL−1) were produced after the fermentation of extracted pectin, hemicellulose, and lignin from S. fruticosa, P. karka, and C. cretica, respectively. Cellulose was methylated (with a degree of substitution of 2.4) and subsequently converted into a composite using polyvinyl alcohol. Scanning electron microscopy and Fourier-transform infrared spectroscopy confirmed the successful synthesis of the composites. The composites made up of cellulose from C. cretica and S. fruticosa had a high tensile strength (21.5 and 15.2 MPa) and low biodegradability (47.58% and 44.56%, respectively) after dumping for 3 months in soil, as compared with the composite from P. karka (98.79% biodegradability and 4.9 MPa tensile strength). Moreover, all the composites exhibited antibacterial activity against gram-negative bacteria (Escherichia coli and Klebsiella pneumoniae) and gram-positive bacteria (Staphylococcus aureus). Hence, this study emphasizes the possibility for various industrial applications of biomass from halophytic plants.","PeriodicalId":8866,"journal":{"name":"Biopolymers","volume":"115 4","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140921067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A facile and scalable method to synthesize PEGylated PDMAEMA for gene delivery 用于基因递送的 PEG 化 PDMAEMA 的简便、可扩展合成方法

IF 3.2 4区生物学

Biopolymers Pub Date : 2024-05-02 DOI: 10.1002/bip.23584

Jie Dou, Shupei Yu, Yuanwei Zhang

引用次数: 0

Synthesis of PEGylated amphiphilic block copolymers with pendant linoleic moieties by combining ring-opening polymerization and click chemistry 结合开环聚合和点击化学，合成具有亚油酸悬垂分子的 PEG 化两亲嵌段共聚物

IF 3.2 4区生物学

Biopolymers Pub Date : 2024-04-29 DOI: 10.1002/bip.23582

Julian D. Porras, Ivonne L. Diaz, Leon D. Perez

{"title":"Synthesis of PEGylated amphiphilic block copolymers with pendant linoleic moieties by combining ring-opening polymerization and click chemistry","authors":"Julian D. Porras, Ivonne L. Diaz, Leon D. Perez","doi":"10.1002/bip.23582","DOIUrl":"10.1002/bip.23582","url":null,"abstract":"This study focused on synthesizing and characterizing PEGylated amphiphilic block copolymers with pendant linoleic acid (Lin) moieties as an alternative to enhance their potential in drug delivery applications. The synthesis involved a two-step process, starting with ring-opening polymerization of ε-caprolactone (CL) and propargylated cyclic carbonate (MCP) to obtain PEG-b-P(CL-co-MCP) copolymers, which were subsequently modified via click chemistry. Various reaction conditions were explored to improve the yield and efficiency of the click chemistry step. The use of anisole as a solvent, N-(3-azidopropyl)linoleamide as a substrate, and a reaction temperature of 60°C proved to be highly efficient, achieving nearly 100% conversion at a low catalyst concentration. The resulting copolymers exhibited controlled molecular weights and low polydispersity, confirming the successful synthesis. Furthermore, click chemistry allows for the attachment of Lin moieties to the copolymer, enhancing its hydrophobic character, as deduced from their significantly lower critical micelle concentration than that of traditional PEG-b-PCL systems, which is indicative of enhanced stability against dilution. The modified copolymers exhibited improved thermal stability, making them suitable for applications that require high processing temperatures. Dynamic light scattering and transmission electron microscopy confirmed the formation of micellar structures with sizes below 100 nm and minimal aggregate formation. Additionally, 1H NMR spectroscopy in deuterated water revealed the presence of core-shell micelles, which provided higher kinetic stability against dilution.","PeriodicalId":8866,"journal":{"name":"Biopolymers","volume":"115 4","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140810105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sustainable strategies towards better utilization of synthetic polymers 更好地利用合成聚合物的可持续战略。

IF 3.2 4区生物学

Biopolymers Pub Date : 2024-04-26 DOI: 10.1002/bip.23581

G. Shanthi, J. Beula Isabel, Rosbin Thankachan, M. Premalatha

{"title":"Sustainable strategies towards better utilization of synthetic polymers","authors":"G. Shanthi, J. Beula Isabel, Rosbin Thankachan, M. Premalatha","doi":"10.1002/bip.23581","DOIUrl":"10.1002/bip.23581","url":null,"abstract":"The abstract provides an overview of a study focused on analyzing diverse strategies to achieve sustainable utilization of synthetic polymers through effective waste management. The escalating global consumption of synthetic polymers has precipitated a concerning increase in plastic waste and environmental degradation. To address this challenge, novel materials with specified application goals, such as engineered plastic, have been developed and are intended for recycling and reuse. Despite the reuse and recycling, when plastic gets disposed into the environment, the degradation properties of plastics render a direct disposal hazard, posing a significant environmental threat. To mitigate these issues, the concept of replacing specific monomers of engineered synthetic plastics with bio-alternatives or blending them with other polymers to enhance sustainability and environmental compatibility has emerged. In this study, Acrylonitrile Butadiene Styrene (ABS) plastic is the focal material, and three distinct investigations were conducted. First, replacing ABS plastic's butadiene monomer with natural rubber was explored for its properties and environmental impact. Second, ABS plastic was blended with virgin, recycled, and bio-alternatives of PET (polyethylene terephthalate) and PVC (polyvinyl chloride) polymers. Lastly, recycled ABS blended with recycled PET and PVC was analyzed for mechanical properties. Comparative assessments of these blends were made based on mechanical properties, carbon emissions, and cost-effectiveness. The study determined that the r-ABS/r-PVC (recycled) blend exhibited the most favorable characteristics for practical application.","PeriodicalId":8866,"journal":{"name":"Biopolymers","volume":"115 4","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140652219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hydroxyapatite-loaded macroporous calcium alginate hydrogels: Preparation, characterization, and in vitro evaluation 负载羟基磷灰石的大孔海藻酸钙水凝胶：制备、表征和体外评估。

IF 3.2 4区生物学

Biopolymers Pub Date : 2024-04-25 DOI: 10.1002/bip.23583

Maria Drozdova, Alika Makhonina, Daria Gladkikh, Alexander Artyukhov, Leonid Bryukhanov, Yaroslav Mezhuev, Vladimir Lozinsky, Elena Markvicheva

引用次数: 0