ASAIO Journal最新文献_第6页

Bridging to Heart Transplantation With Intraaortic Balloon Pump Versus Impella 5.5. 主动脉内球囊泵与Impella 5.5的心脏移植桥接。

IF 3.1 3区医学

ASAIO Journal Pub Date : 2025-04-02 DOI: 10.1097/MAT.0000000000002432

Spencer E Kim, Max Shin, Amit Iyengar, Noah Weingarten, Dun Jin, Rachel Wilson, Michaela Asher, Omar Toubat, Pavan Atluri

{"title":"Bridging to Heart Transplantation With Intraaortic Balloon Pump Versus Impella 5.5.","authors":"Spencer E Kim, Max Shin, Amit Iyengar, Noah Weingarten, Dun Jin, Rachel Wilson, Michaela Asher, Omar Toubat, Pavan Atluri","doi":"10.1097/MAT.0000000000002432","DOIUrl":"https://doi.org/10.1097/MAT.0000000000002432","url":null,"abstract":"In this study, we compare the clinical characteristics and courses of patients directly bridged to heart transplant with intraaortic balloon pump (IABP) versus Impella 5.5. We performed a retrospective cohort study of single-center institutional data including all adult patients at our institution bridged to transplant with either IABP or Impella 5.5 support between October 18, 2018, and May 31, 2023. Ninety-one heart transplant recipients were included in this study, of whom 54 (59%) were bridged on IABP and 37 (41%) were bridged on Impella 5.5. Patients supported with Impella 5.5 had comparable baseline characteristics compared to those bridged on IABP (all p > 0.05). However, Impella 5.5 patients had lower vasoactive inotropic scores during their temporary mechanical circulatory support (MCS) period than those bridged on IABP (all p < 0.05). Duration of MCS and post-transplant intensive care unit (ICU) length of stay were longer for Impella 5.5 patients (all p < 0.05), but rates of complications after transplant were comparable (all p > 0.05). Survival at 1 year post-transplant was significantly greater for the Impella 5.5 group (100% vs. 87%; p = 0.039). Given the increased use of MCS as a bridge to transplant, this project has important implications for preoperative management of waitlist patients.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143762604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultra-Low-Field Portable Brain Magnetic Resonance Imaging in Patients With Cardiac Devices: Current Evidence and Future Directions. 心脏装置患者的超低场便携式脑磁共振成像：目前的证据和未来的方向。

IF 3.1 3区医学

ASAIO Journal Pub Date : 2025-04-01 Epub Date: 2025-01-30 DOI: 10.1097/MAT.0000000000002368

Shivalika Khanduja, Jin K Kang, Ifeanyi D Chinedozi, Zachary Darby, Jiah Kim, Glenn Whitman, Sung-Min Cho

{"title":"Ultra-Low-Field Portable Brain Magnetic Resonance Imaging in Patients With Cardiac Devices: Current Evidence and Future Directions.","authors":"Shivalika Khanduja, Jin K Kang, Ifeanyi D Chinedozi, Zachary Darby, Jiah Kim, Glenn Whitman, Sung-Min Cho","doi":"10.1097/MAT.0000000000002368","DOIUrl":"10.1097/MAT.0000000000002368","url":null,"abstract":"The use of cardiac devices, including mechanical circulatory support (MCS), cardiac implantable electronic devices (CIEDs), and pacing wires, has increased and significantly improved survival in patients with severe cardiac failure. However, these devices are frequently associated with acute brain injuries (ABIs) including ischemic strokes, intracranial hemorrhages, seizures, and hypoxic-ischemic brain injury which contribute substantially to morbidity and mortality. Computed tomography (CT) and magnetic resonance imaging (MRI), the standard imaging modalities for ABI diagnosis, can pose significant challenges in this patient population due to the risks associated with patient transportation and the incompatibility of ferromagnetic components of certain cardiac devices with high magnetic field of the MRI. This review discusses the application of Ultralow-field portable MRI (ULF-pMRI), which operates at much lower magnetic field (0.064 T), with the potential to allow safe bedside imaging of critically ill patients. In this review, we detail the clinical studies and research findings defining the safety, feasibility, and diagnostic utility of ULF-pMRI in detecting ABI in the critically ill. We further discuss the potential broader applications of ULF-pMRI, as a standard diagnostic tool for neurocritical care in patients with cardiac devices. The integration of such technology into current practice promises to enhance diagnostic accuracy, improve patient outcomes, and optimize healthcare resources.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":"277-282"},"PeriodicalIF":3.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143063325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extracorporeal Membrane Oxygenation for COVID-19 During the Delta and Omicron Waves in North America. 北美德尔塔波和欧米茄波期间为 COVID-19 进行体外膜氧合。

IF 3.1 3区医学

ASAIO Journal Pub Date : 2025-04-01 Epub Date: 2024-10-22 DOI: 10.1097/MAT.0000000000002334

Andrew J Hickey, Richard Greendyk, Matthew J Cummings, Darryl Abrams, Max R O'Donnell, Craig R Rackley, Ryan P Barbaro, Daniel Brodie, Cara Agerstrand

{"title":"Extracorporeal Membrane Oxygenation for COVID-19 During the Delta and Omicron Waves in North America.","authors":"Andrew J Hickey, Richard Greendyk, Matthew J Cummings, Darryl Abrams, Max R O'Donnell, Craig R Rackley, Ryan P Barbaro, Daniel Brodie, Cara Agerstrand","doi":"10.1097/MAT.0000000000002334","DOIUrl":"10.1097/MAT.0000000000002334","url":null,"abstract":"Clinical outcomes for patients with severe acute respiratory failure caused by different variants of the coronavirus disease 2019 (COVID-19) supported with extracorporeal membrane oxygenation (ECMO) are incompletely understood. Clinical characteristics, pre-ECMO management, and hospital mortality at 90 days for adults with COVID-19 who received venovenous ECMO (VV-ECMO) at North American centers during waves predominated by Delta (August 16 to December 12, 2021) and Omicron (January 31 to May 31, 2022) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants were compared in a competing risks framework. One thousand seven hundred and sixty-six patients (1,580 Delta, 186 Omicron) received VV-ECMO for COVID-19 during the Delta- and Omicron-predominant waves in North American centers. In the unadjusted competing risks model, no significant difference was observed in risk of hospital mortality at 90 days between patients during the Delta- versus Omicron-predominant wave (subhazard ratio [sHR], 0.94; 95% confidence interval [CI], 0.74-1.19), but patients supported with VV-ECMO during the Omicron-predominant wave had a significantly lower adjusted risk of hospital mortality at 90 days (subhazard ratio, 0.71; 95% CI, 0.51-0.99). Patients receiving VV-ECMO during the Omicron-predominant wave had a similar unadjusted risk of hospital mortality at 90 days, but a significantly lower adjusted risk of hospital mortality at 90 days than those receiving VV-ECMO during the Delta-predominant wave.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":"325-331"},"PeriodicalIF":3.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142493965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thoracoabdominal Normothermic Regional Perfusion Using Mobile Closed Extracorporeal Circuit in Circulatory Death Determination Heart Donors. 使用移动式封闭体外循环对循环死亡确定心脏捐献者进行胸腹腔常温区域灌注。

IF 3.1 3区医学

ASAIO Journal Pub Date : 2025-04-01 Epub Date: 2024-08-13 DOI: 10.1097/MAT.0000000000002282

Marta Velia Antonini, Sofia Martin-Suàrez, Luca Botta, Alessandro Circelli, Erika Cordella, Gianluca Zani, Marina Terzitta, Vanni Agnoletti, Davide Pacini

{"title":"Thoracoabdominal Normothermic Regional Perfusion Using Mobile Closed Extracorporeal Circuit in Circulatory Death Determination Heart Donors.","authors":"Marta Velia Antonini, Sofia Martin-Suàrez, Luca Botta, Alessandro Circelli, Erika Cordella, Gianluca Zani, Marina Terzitta, Vanni Agnoletti, Davide Pacini","doi":"10.1097/MAT.0000000000002282","DOIUrl":"10.1097/MAT.0000000000002282","url":null,"abstract":"Thoracoabdominal normothermic regional perfusion (TA-NRP) is increasingly implemented in donation after circulatory determination of death (DCD). Thoracoabdominal normothermic regional perfusion allows thoracic and abdominal organs to be perfused with warm, oxygenated blood after declaration of death, interrupting ischemia. Evidence is accumulating supporting the use of TA-NRP to improve the outcome of grafts from DCD donors. Thoracoabdominal normothermic regional perfusion may restore and maintain a near-physiological environment during procurement. Moreover, during TA-NRP it is feasible to evaluate the heart in situ . Thoracoabdominal normothermic regional perfusion could be performed through different cannulation techniques, central or peripheral, and, with different extracorporeal circuits. The use of conventional cardiopulmonary bypass and extracorporeal life support (ECLS) devices equipped with open circuits has been described. We report the use of a fully mobile, closed ECLS circuit to implement TA-NRP. The procedure was successfully performed in a peripheral center without a cardiac surgery program through a percutaneous cannulation approach. This strategy resulted in combined heart, liver, and kidney recovery despite a significantly prolonged functional warm ischemia time. The feasibility of TA-NRP using modified but still closed fully mobile ECLS circuits could furtherly support the expansion of DCD programs, increasing the availability of heart for transplantation, and the quality of the grafts, improving recipients' outcome.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":"e61-e65"},"PeriodicalIF":3.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141981570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Outcomes of Multiorgan Heart Transplant Between Donation After Circulatory Death and Brain Death. 循环死亡和脑死亡后捐献多器官心脏移植的结果。

IF 3.1 3区医学

ASAIO Journal Pub Date : 2025-04-01 Epub Date: 2024-10-14 DOI: 10.1097/MAT.0000000000002329

Toyokazu Endo, Jaimin R Trivedi, Stephanie Moore, Sheng Fu, Rohan Samson, Michele Gallo, Siddharth Pahwa, Mark S Slaughter, Erin M Schumer

{"title":"Outcomes of Multiorgan Heart Transplant Between Donation After Circulatory Death and Brain Death.","authors":"Toyokazu Endo, Jaimin R Trivedi, Stephanie Moore, Sheng Fu, Rohan Samson, Michele Gallo, Siddharth Pahwa, Mark S Slaughter, Erin M Schumer","doi":"10.1097/MAT.0000000000002329","DOIUrl":"10.1097/MAT.0000000000002329","url":null,"abstract":"There is insufficient data on the outcomes of donation after circulatory death (DCD) multiorgan transplant that includes heart. The primary objective of this study is to compare the overall survival outcomes of DCD and donation after brain death (DBD) multiorgan transplants. We identified all heart transplant patients from 2019 to June of 2023 using the United Network for Organ Sharing (UNOS) Database who also received an additional organ (kidney, liver, and lungs). A total of 1,844 DBD and 91 DCD multiorgan transplants occurred within the study period, the majority being combined heart-kidney transplantation. More patients were listed at a higher status in the DBD group ( p < 0.05) and were in the intensive care unit (ICU) before transplant ( p < 0.05). Despite the higher ischemia time in the DCD group ( p < 0.05), the overall unmatched survival did not differ between the two groups ( p < 0.05). Within the heart-kidney transplants, the overall survival between DBD and DCD heart-kidney transplants did not differ in either unmatched or matched groups (unmatched p = 0.5, matched p = 0.5). In conclusion, the data on the outcomes of DCD multiorgan transplants are limited. Still, our analysis of the currently available data suggests that the overall survival is comparable in the DCD multiorgan transplants.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":"316-324"},"PeriodicalIF":3.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142457088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extubated, Rehabilitation-Focused Extracorporeal Membrane Oxygenation for Pediatric Coronavirus Disease 2019: A Case Series. 2019年小儿冠状病毒病的拔管、以康复为重点的体外膜氧合：病例系列。

IF 3.1 3区医学

ASAIO Journal Pub Date : 2025-04-01 Epub Date: 2024-07-25 DOI: 10.1097/MAT.0000000000002281

Kevin B Kilgallon, Matthew Leroue, Sara Shankman, Taryn Shea, Shannon Buckvold, Max Mitchell, Gareth Morgan, Jenny Zablah, Aline B Maddux

{"title":"Extubated, Rehabilitation-Focused Extracorporeal Membrane Oxygenation for Pediatric Coronavirus Disease 2019: A Case Series.","authors":"Kevin B Kilgallon, Matthew Leroue, Sara Shankman, Taryn Shea, Shannon Buckvold, Max Mitchell, Gareth Morgan, Jenny Zablah, Aline B Maddux","doi":"10.1097/MAT.0000000000002281","DOIUrl":"10.1097/MAT.0000000000002281","url":null,"abstract":"During the coronavirus 2019 (COVID-19) pandemic, children suffered severe lung injury resulting in acute respiratory distress syndrome requiring support with extracorporeal membrane oxygenation (ECMO). In this case series, we described our center's experience employing a rehabilitation-focused ECMO strategy including extubation during ECMO support in four pediatric patients with acute COVID-19 pneumonia hospitalized from September 2021 to January 2022. All four patients tolerated extubation within 30 days of ECMO initiation and achieved mobility while on ECMO support. Duration of ECMO support was 35-152 days and hospital lengths of stay were 52-167 days. Three of four patients survived. Two of three survivors had normal functional status at discharge except for ongoing respiratory support. The third survivor had significant motor deficits due to critical illness polyneuropathy and was supported with daytime oxygen and nocturnal noninvasive support. Overall, these patients demonstrated good outcomes and tolerance of a rehabilitation-focused ECMO strategy.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":"e66-e71"},"PeriodicalIF":3.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141756905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Estimation of Absolute Blood Volume Using Online Dialysate Dilution: When and How to Measure? 使用在线透析液稀释估算绝对血容量：何时以及如何测量？

IF 3.1 3区医学

ASAIO Journal Pub Date : 2025-04-01 Epub Date: 2024-08-01 DOI: 10.1097/MAT.0000000000002284

Joachim Kron, Susanne Kron

引用次数: 0

Multiple Pediatric Extracorporeal Membrane Oxygenation Runs and Futility. What Are the Limits? 多次小儿体外膜氧合运行与无用论。极限是什么？

IF 3.1 3区医学

ASAIO Journal Pub Date : 2025-04-01 Epub Date: 2024-10-18 DOI: 10.1097/MAT.0000000000002325

Justus G Reitz, Areen Almarkhan, Rittal Mehta, Arif Selcuk, Dana Harrar, Manan Desai, Guillermo Herrera, In Hye Park, Aybala Tongut, Yves d'Udekem, Sarah Schlatterer

{"title":"Multiple Pediatric Extracorporeal Membrane Oxygenation Runs and Futility. What Are the Limits?","authors":"Justus G Reitz, Areen Almarkhan, Rittal Mehta, Arif Selcuk, Dana Harrar, Manan Desai, Guillermo Herrera, In Hye Park, Aybala Tongut, Yves d'Udekem, Sarah Schlatterer","doi":"10.1097/MAT.0000000000002325","DOIUrl":"10.1097/MAT.0000000000002325","url":null,"abstract":"Despite high mortality rates, pediatric extracorporeal membrane oxygenation (ECMO) redeployments are frequently discussed in everyday clinical care. We aim to investigate predictors of mortality in those patients. Clinical data from a single pediatric center were retrospectively analyzed. Patients with multiple ECMO runs between 2010 and 2023 were included. A total of 70 (13%) patients required multiple ECMO runs. Of those, 56 (80%) died before discharge; late mortality was 89% at a median of 1.6 (1.0-3.9) years. A total of 47 (67%) patients had neurologic findings. Only one (1%) survivor had a normal neurodevelopmental follow-up. Duration of the first ECMO run (odds ratio [OR]: 2.63, 1.08-7.96), total duration on ECMO (OR: 4.72, 1.29-23.54), neurologic findings at any time (OR: 7.94, 1.46-43.24), need for renal replacement therapy (OR: 4.79, 1.06-25.58), and lactate values correlated with late mortality. All 19 (27%) patients with neurologic findings before the second run died. The frequency of multiple-run ECMOs increased within the study period. Outcomes in pediatric patients with multiple ECMO runs are disheartening. Given all patients in our cohort with neurological findings before the second ECMO run died, neurological findings should be taken into consideration when determining the utility of further ECMO support.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":"345-354"},"PeriodicalIF":3.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142457086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chilling Choices: Heart Transplant Outcomes Using SherpaPak With Long Ischemic Time Versus Traditional Ice Storage With Short Ischemic Time. 冷冻选择：长缺血时间的SherpaPak与短缺血时间的传统冰储存的心脏移植结果。

IF 3.1 3区医学

ASAIO Journal Pub Date : 2025-04-01 Epub Date: 2024-12-12 DOI: 10.1097/MAT.0000000000002357

Hassan Farhoud, Zubair Shah, Tarun Dalia, Scott Silvestry, Hirak Shah, Dan Meyer, David DʼAlessandro, Andrija Vidic

{"title":"Chilling Choices: Heart Transplant Outcomes Using SherpaPak With Long Ischemic Time Versus Traditional Ice Storage With Short Ischemic Time.","authors":"Hassan Farhoud, Zubair Shah, Tarun Dalia, Scott Silvestry, Hirak Shah, Dan Meyer, David DʼAlessandro, Andrija Vidic","doi":"10.1097/MAT.0000000000002357","DOIUrl":"10.1097/MAT.0000000000002357","url":null,"abstract":"We performed a retrospective review comparing outcomes between traditional ice storage (ICE) with short ischemic times (<3 hours) to SherpaPak Cardiac Transport System (SCTS) with long ischemic times (>4 hours) using data from the GUARDIAN registry, a retrospective observational trial. To minimize baseline differences, propensity-matched (PSM) cohorts for site and era were performed. SherpaPak Cardiac Transport System travel distance was almost 10-fold greater than ICE (82 miles ICE vs . 765 miles SCTS). There was no significant difference in primary graft dysfunction (PGD) (20.8% vs. 18.2%, p = 0.58), length of stay (LOS) (24.7 vs. 24.8, p = 0.98), posttransplant mechanical circulatory support (MCS) (25.1% vs. 20.3%, p = 0.34), and 30 day survival (100% vs. 98.6%, p = 0.20). SherpaPak Cardiac Transport System showed statistically significant reduction in 24 hour inotrope scores (17.6 vs. 13.6, p = 0.007) and right ventricular (RV) dysfunction (31.1% vs. 15.7%, p = 0.002). Propensity-matched cohorts showed statistically similar rates of MCS utilization and PGD, but SCTS trended toward less RV dysfunction (26.0% vs. 16.2%, p = 0.11) and lower inotrope scores (16.5 vs. 12.9, p = 0.06) despite almost double the ischemic time. In conclusion, donor heart preservation with SCTS continues to be effective in prolonged ischemic times without sacrificing postheart transplantation clinical outcomes. This may aid in expanding donor organ geography.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":"308-315"},"PeriodicalIF":3.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11949210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antepartum Extracorporeal Life Support: A Viable Way to Improve Fetal Outcomes. 产前体外生命支持：一种改善胎儿结局的可行方法。

IF 3.1 3区医学

ASAIO Journal Pub Date : 2025-04-01 Epub Date: 2025-03-06 DOI: 10.1097/MAT.0000000000002413

Maya Guglin, Dmitry Abramov

引用次数: 0