ASAIO Journal最新文献

Pattern and Outcomes of Stroke in Cardiogenic Shock Patients Supported by Impella 5.5. 由 Impella 5.5 支持的心源性休克患者中风的模式和预后。

IF 3.1 3区医学

ASAIO Journal Pub Date : 2025-04-04 DOI: 10.1097/MAT.0000000000002429

Kevin John John, Mohamad Wahoud, Christopher Rago, Masashi Kawabori, Lester Y Leung, Navin K Kapur, Haval Chweich

引用次数: 0

Clinical Relevance of Platelet-Leukocyte Aggregates and Platelet P-Selectin Expression During Venovenous Extracorporeal Membrane Oxygenation.

IF 3.1 3区医学

ASAIO Journal Pub Date : 2025-04-03 DOI: 10.1097/MAT.0000000000002421

Lukas Paschke, Maik Foltan, Maria S Wagner, Matthias Lubnow, Michael Gruber, Lars Krenkel, Karla Lehle

{"title":"Clinical Relevance of Platelet-Leukocyte Aggregates and Platelet P-Selectin Expression During Venovenous Extracorporeal Membrane Oxygenation.","authors":"Lukas Paschke, Maik Foltan, Maria S Wagner, Matthias Lubnow, Michael Gruber, Lars Krenkel, Karla Lehle","doi":"10.1097/MAT.0000000000002421","DOIUrl":"https://doi.org/10.1097/MAT.0000000000002421","url":null,"abstract":"Thrombosis continues to be a significant complication during venovenous extracorporeal membrane oxygenation (V-V ECMO). Platelet activation markers might serve as indicators of inflammation and thrombogenesis. The aim was to identify these markers in ECMO patients. Blood from 10 ECMO patients (before, during, after ECMO) and 11 healthy volunteers were collected to determine platelet-neutrophil-aggregates (PNAs), platelet-monocyte-aggregates (PMAs), fibrinogen-binding, and P-selectin-expression on platelets by flow cytometry. Critical illness was associated with significantly elevated levels of PNAs and PMAs, increased P-selectin expression, reduced fibrinogen-binding, and restricted activation of platelets. Although PNAs and PMAs decreased significantly within 2 hours after the initiation of ECMO and remained at those levels, ECMO did not affect basal P-selectin expression and fibrinogen-binding. These results correlated with coagulation activation. Platelet markers before ECMO were not indicators for an imminent system exchange and end of therapy. In conclusion, platelet dysfunction during ECMO was mainly attributed to the critical illness. Extracorporeal membrane oxygenation support strengthened the restricted response of platelets to exogenous agonists (P-selectin). Furthermore, a decrease in PNAs/PMAs after ECMO started identified a reduced inflammatory response. There was no correlation of analyzed platelet parameters with the incidence of thrombotic complications.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143771252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impeller Position in a Magnetically Levitated Rotodynamic Blood Pump and Its Impact on In-Silico Hemocompatibility. 磁悬浮旋转动力血液泵的叶轮位置及其对模拟血液相容性的影响

IF 3.1 3区医学

ASAIO Journal Pub Date : 2025-04-03 DOI: 10.1097/MAT.0000000000002434

Marko Grujic, Rosmarie Schoefbeck, Bente Thamsen, Philipp Aigner, Michael Röhrich, Stefan Jakubek, Daniel Zimpfer, Marcus Granegger

{"title":"Impeller Position in a Magnetically Levitated Rotodynamic Blood Pump and Its Impact on In-Silico Hemocompatibility.","authors":"Marko Grujic, Rosmarie Schoefbeck, Bente Thamsen, Philipp Aigner, Michael Röhrich, Stefan Jakubek, Daniel Zimpfer, Marcus Granegger","doi":"10.1097/MAT.0000000000002434","DOIUrl":"https://doi.org/10.1097/MAT.0000000000002434","url":null,"abstract":"In magnetically levitated rotodynamic blood pumps (RPBs), the impeller position depends on a balance of electromagnetic and fluid dynamic forces. The aim of this study was to describe the impeller position of the HeartMate 3 over a wide range of operating conditions and assess its potential impact on hemocompatibility. Three-dimensional impeller positions were measured using a transparent HeartMate 3 pump casing, laser distance measurements, and a high-speed camera. Accompanying computational fluid dynamic (CFD) hemocompatibility predictions of a displaced and centered impeller at a typical operating point were compared. Impeller positions vary substantially with different operating points with a maximum axial displacement of 223 µm at 7 L/min and 7,000 rpm and a maximum radial displacement of 145 µm at 0 L/min and 7,000 rpm. In CFD, a displaced impeller had only a minor influence on global pump parameters (<2%) at an operating point of 5 L/min and 6,000 rpm. However, deviations in local flow metrics of up to 9% were observed compared with a centered impeller simulation. We here provide the impeller position of the HeartMate 3 over the full operating range (0-9 L/min, 3,000-7,000 rpm) to support further research, including more extensive CFD simulations.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mechanical Subpulmonary Support in Fontan Circulation: A Juvenile Porcine Experimental Model.

IF 3.1 3区医学

ASAIO Journal Pub Date : 2025-04-02 DOI: 10.1097/MAT.0000000000002427

Naoya Sakoda, Yasuyuki Kobayashi, Daichi Edaki, Shingo Kasahara, Yasuhiro Kotani

{"title":"Mechanical Subpulmonary Support in Fontan Circulation: A Juvenile Porcine Experimental Model.","authors":"Naoya Sakoda, Yasuyuki Kobayashi, Daichi Edaki, Shingo Kasahara, Yasuhiro Kotani","doi":"10.1097/MAT.0000000000002427","DOIUrl":"https://doi.org/10.1097/MAT.0000000000002427","url":null,"abstract":"Mechanical cavopulmonary assist (CPA) remains challenging for failing Fontan circulation. This study aimed to evaluate the hemodynamic impact of partial CPA using a juvenile porcine model. Six pigs (30 kg) underwent the Fontan procedure using a handmade Y-shaped graft. Total CPA was established by assisting both superior vena cava (SVC) and inferior vena cava (IVC) flow to the pulmonary artery, whereas partial CPA assisted only IVC flow using a centrifugal pump. Cavopulmonary assist flow was set to 100%, 50%, or 25% of pre-Fontan cardiac output (CO). Hemodynamics at baseline, after total CPA, and after partial CPA were compared using paired t-tests. Total CPA with 100% CO support increased CO and reduced SVC and IVC pressures compared to baseline (CO, 1.03 vs. 2.36 L/min; SVC pressure, 16.3 vs. 9.5 mm Hg; IVC pressure, 17.3 vs. 9.3 mm Hg, p < 0.05 for all). Partial CPA with 25% CO support increased CO and decreased IVC pressure, though SVC pressure increased (CO, 1.03 vs. 1.52 L/min; SVC pressure, 16.3 vs. 20.5 mm Hg; IVC pressure, 17.3 vs. 11.5 mm Hg, p < 0.05 for all). Although total CPA achieved optimal hemodynamics, partial CPA with 25% CO flow was effective, suggesting a feasible, noninvasive solution for patients with failing Fontan physiology.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143762610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Racial and Sex Disparities in Incidence, Risk Factors, and Outcomes of Neonatal Extracorporeal Life Support in the United States.

IF 3.1 3区医学

ASAIO Journal Pub Date : 2025-04-02 DOI: 10.1097/MAT.0000000000002423

Lauren R Walker, Laura E Hollinger, Lizmarie Maldonado, Mulugeta Gebregziabher, Brian K Stansfield, Natalie Rintoul, Connor Kreese, Heidi J Steflik

{"title":"Racial and Sex Disparities in Incidence, Risk Factors, and Outcomes of Neonatal Extracorporeal Life Support in the United States.","authors":"Lauren R Walker, Laura E Hollinger, Lizmarie Maldonado, Mulugeta Gebregziabher, Brian K Stansfield, Natalie Rintoul, Connor Kreese, Heidi J Steflik","doi":"10.1097/MAT.0000000000002423","DOIUrl":"https://doi.org/10.1097/MAT.0000000000002423","url":null,"abstract":"The impact of race on extracorporeal life support (ECLS) availability, morbidity, and mortality remains poorly defined. We sought to define the impact of race/ethnicity, sex, and location on ECLS outcomes, and identify potential disparities that remain intact using a modern, inclusive cohort of neonates receiving ECLS in the United States. Data were extracted from the Children's Hospital Association Pediatric Health Information System (PHIS) database on neonates who received ECLS from January 1, 2010-December 31, 2020. Both adjusted and unadjusted regression models were fitted to study the association between neonatal ECLS outcomes and covariates. During the study period, 6,695 neonates from 47 hospitals met the inclusion criteria. Non-Hispanic White neonates (45%), males (57%), and hospitals in the Southern region (32%) compromised the largest proportions of ECLS cases and cardiac disease (44%) was the most common indication for ECLS. Hospital region was associated with ECLS duration with hospitals in the Midwest (median 6 days) and West (6 days) having significantly shorter courses than those in the Northeast (7 days) and South (7 days) (p < 0.01). Associations between race/ethnicity, sex, hospital region, and mortality were detected. Non-Hispanic Black neonates (35% mortality), males (37%), and neonates in the Midwest region (34%) experienced lower ECLS mortality rates (all p < 0.05).","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143762623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association Between Red Blood Cells Transfusion and 1 Year Mortality in Patients on Venoarterial Extracorporeal Membrane Oxygenation for Cardiogenic Shock.

IF 3.1 3区医学

ASAIO Journal Pub Date : 2025-04-02 DOI: 10.1097/MAT.0000000000002424

Mathilde Brouland, Antoine Kimmoun, Clément Delmas, Kevin Duarte, Nicolas Girerd, Fanny Vardon-Bounes, Thomas Klein

{"title":"Association Between Red Blood Cells Transfusion and 1 Year Mortality in Patients on Venoarterial Extracorporeal Membrane Oxygenation for Cardiogenic Shock.","authors":"Mathilde Brouland, Antoine Kimmoun, Clément Delmas, Kevin Duarte, Nicolas Girerd, Fanny Vardon-Bounes, Thomas Klein","doi":"10.1097/MAT.0000000000002424","DOIUrl":"https://doi.org/10.1097/MAT.0000000000002424","url":null,"abstract":"In patients on venoarterial extracorporeal membrane oxygenation (VA-ECMO) for cardiogenic shock, red blood cell (RBC) transfusion is often necessary, but its impact on long-term mortality remains unclear. This multicenter retrospective cohort study aimed to assess the association between RBC transfusion and 1 year mortality in patients on VA-ECMO. Data were collected from two French intensive care units (ICUs) between January 1st, 2016, and December 31st, 2021. Adults with cardiogenic shock supported by VA-ECMO were included, while those under 18, with ECMO duration <24 hours, or cardiac arrest before or during implantation were excluded. Among 190 patients (71% male, median age 60 years), the median VA-ECMO duration was 8 days. One year mortality was 54%. Red blood cell transfusions were administered to 83% of patients, with a median of six packs. Multivariable analysis showed no significant association between RBC transfusion and 1 year mortality across various transfusion metrics, including transfusion status, total units, and daily packs (all p > 0.05). Subgroup analyses confirmed this consistent pattern. Although RBC transfusion is frequent in VA-ECMO-supported patients, this study found no significant association with 1 year survival. Given the risks of transfusion, a cautious approach is recommended. Further studies are needed to refine transfusion strategies for this high-risk population.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143762452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bridging to Heart Transplantation With Intraaortic Balloon Pump Versus Impella 5.5.

IF 3.1 3区医学

ASAIO Journal Pub Date : 2025-04-02 DOI: 10.1097/MAT.0000000000002432

Spencer E Kim, Max Shin, Amit Iyengar, Noah Weingarten, Dun Jin, Rachel Wilson, Michaela Asher, Omar Toubat, Pavan Atluri

{"title":"Bridging to Heart Transplantation With Intraaortic Balloon Pump Versus Impella 5.5.","authors":"Spencer E Kim, Max Shin, Amit Iyengar, Noah Weingarten, Dun Jin, Rachel Wilson, Michaela Asher, Omar Toubat, Pavan Atluri","doi":"10.1097/MAT.0000000000002432","DOIUrl":"https://doi.org/10.1097/MAT.0000000000002432","url":null,"abstract":"In this study, we compare the clinical characteristics and courses of patients directly bridged to heart transplant with intraaortic balloon pump (IABP) versus Impella 5.5. We performed a retrospective cohort study of single-center institutional data including all adult patients at our institution bridged to transplant with either IABP or Impella 5.5 support between October 18, 2018, and May 31, 2023. Ninety-one heart transplant recipients were included in this study, of whom 54 (59%) were bridged on IABP and 37 (41%) were bridged on Impella 5.5. Patients supported with Impella 5.5 had comparable baseline characteristics compared to those bridged on IABP (all p > 0.05). However, Impella 5.5 patients had lower vasoactive inotropic scores during their temporary mechanical circulatory support (MCS) period than those bridged on IABP (all p < 0.05). Duration of MCS and post-transplant intensive care unit (ICU) length of stay were longer for Impella 5.5 patients (all p < 0.05), but rates of complications after transplant were comparable (all p > 0.05). Survival at 1 year post-transplant was significantly greater for the Impella 5.5 group (100% vs. 87%; p = 0.039). Given the increased use of MCS as a bridge to transplant, this project has important implications for preoperative management of waitlist patients.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143762604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thoracoabdominal Normothermic Regional Perfusion Using Mobile Closed Extracorporeal Circuit in Circulatory Death Determination Heart Donors. 使用移动式封闭体外循环对循环死亡确定心脏捐献者进行胸腹腔常温区域灌注。

IF 3.1 3区医学

ASAIO Journal Pub Date : 2025-04-01 Epub Date: 2024-08-13 DOI: 10.1097/MAT.0000000000002282

Marta Velia Antonini, Sofia Martin-Suàrez, Luca Botta, Alessandro Circelli, Erika Cordella, Gianluca Zani, Marina Terzitta, Vanni Agnoletti, Davide Pacini

{"title":"Thoracoabdominal Normothermic Regional Perfusion Using Mobile Closed Extracorporeal Circuit in Circulatory Death Determination Heart Donors.","authors":"Marta Velia Antonini, Sofia Martin-Suàrez, Luca Botta, Alessandro Circelli, Erika Cordella, Gianluca Zani, Marina Terzitta, Vanni Agnoletti, Davide Pacini","doi":"10.1097/MAT.0000000000002282","DOIUrl":"10.1097/MAT.0000000000002282","url":null,"abstract":"Thoracoabdominal normothermic regional perfusion (TA-NRP) is increasingly implemented in donation after circulatory determination of death (DCD). Thoracoabdominal normothermic regional perfusion allows thoracic and abdominal organs to be perfused with warm, oxygenated blood after declaration of death, interrupting ischemia. Evidence is accumulating supporting the use of TA-NRP to improve the outcome of grafts from DCD donors. Thoracoabdominal normothermic regional perfusion may restore and maintain a near-physiological environment during procurement. Moreover, during TA-NRP it is feasible to evaluate the heart in situ . Thoracoabdominal normothermic regional perfusion could be performed through different cannulation techniques, central or peripheral, and, with different extracorporeal circuits. The use of conventional cardiopulmonary bypass and extracorporeal life support (ECLS) devices equipped with open circuits has been described. We report the use of a fully mobile, closed ECLS circuit to implement TA-NRP. The procedure was successfully performed in a peripheral center without a cardiac surgery program through a percutaneous cannulation approach. This strategy resulted in combined heart, liver, and kidney recovery despite a significantly prolonged functional warm ischemia time. The feasibility of TA-NRP using modified but still closed fully mobile ECLS circuits could furtherly support the expansion of DCD programs, increasing the availability of heart for transplantation, and the quality of the grafts, improving recipients' outcome.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":"e61-e65"},"PeriodicalIF":3.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141981570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extracorporeal Membrane Oxygenation for COVID-19 During the Delta and Omicron Waves in North America. 北美德尔塔波和欧米茄波期间为 COVID-19 进行体外膜氧合。

IF 3.1 3区医学

ASAIO Journal Pub Date : 2025-04-01 Epub Date: 2024-10-22 DOI: 10.1097/MAT.0000000000002334

Andrew J Hickey, Richard Greendyk, Matthew J Cummings, Darryl Abrams, Max R O'Donnell, Craig R Rackley, Ryan P Barbaro, Daniel Brodie, Cara Agerstrand

{"title":"Extracorporeal Membrane Oxygenation for COVID-19 During the Delta and Omicron Waves in North America.","authors":"Andrew J Hickey, Richard Greendyk, Matthew J Cummings, Darryl Abrams, Max R O'Donnell, Craig R Rackley, Ryan P Barbaro, Daniel Brodie, Cara Agerstrand","doi":"10.1097/MAT.0000000000002334","DOIUrl":"10.1097/MAT.0000000000002334","url":null,"abstract":"Clinical outcomes for patients with severe acute respiratory failure caused by different variants of the coronavirus disease 2019 (COVID-19) supported with extracorporeal membrane oxygenation (ECMO) are incompletely understood. Clinical characteristics, pre-ECMO management, and hospital mortality at 90 days for adults with COVID-19 who received venovenous ECMO (VV-ECMO) at North American centers during waves predominated by Delta (August 16 to December 12, 2021) and Omicron (January 31 to May 31, 2022) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants were compared in a competing risks framework. One thousand seven hundred and sixty-six patients (1,580 Delta, 186 Omicron) received VV-ECMO for COVID-19 during the Delta- and Omicron-predominant waves in North American centers. In the unadjusted competing risks model, no significant difference was observed in risk of hospital mortality at 90 days between patients during the Delta- versus Omicron-predominant wave (subhazard ratio [sHR], 0.94; 95% confidence interval [CI], 0.74-1.19), but patients supported with VV-ECMO during the Omicron-predominant wave had a significantly lower adjusted risk of hospital mortality at 90 days (subhazard ratio, 0.71; 95% CI, 0.51-0.99). Patients receiving VV-ECMO during the Omicron-predominant wave had a similar unadjusted risk of hospital mortality at 90 days, but a significantly lower adjusted risk of hospital mortality at 90 days than those receiving VV-ECMO during the Delta-predominant wave.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":"325-331"},"PeriodicalIF":3.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142493965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultra-Low-Field Portable Brain Magnetic Resonance Imaging in Patients With Cardiac Devices: Current Evidence and Future Directions.

IF 3.1 3区医学

ASAIO Journal Pub Date : 2025-04-01 Epub Date: 2025-01-30 DOI: 10.1097/MAT.0000000000002368

Shivalika Khanduja, Jin K Kang, Ifeanyi D Chinedozi, Zachary Darby, Jiah Kim, Glenn Whitman, Sung-Min Cho

{"title":"Ultra-Low-Field Portable Brain Magnetic Resonance Imaging in Patients With Cardiac Devices: Current Evidence and Future Directions.","authors":"Shivalika Khanduja, Jin K Kang, Ifeanyi D Chinedozi, Zachary Darby, Jiah Kim, Glenn Whitman, Sung-Min Cho","doi":"10.1097/MAT.0000000000002368","DOIUrl":"10.1097/MAT.0000000000002368","url":null,"abstract":"The use of cardiac devices, including mechanical circulatory support (MCS), cardiac implantable electronic devices (CIEDs), and pacing wires, has increased and significantly improved survival in patients with severe cardiac failure. However, these devices are frequently associated with acute brain injuries (ABIs) including ischemic strokes, intracranial hemorrhages, seizures, and hypoxic-ischemic brain injury which contribute substantially to morbidity and mortality. Computed tomography (CT) and magnetic resonance imaging (MRI), the standard imaging modalities for ABI diagnosis, can pose significant challenges in this patient population due to the risks associated with patient transportation and the incompatibility of ferromagnetic components of certain cardiac devices with high magnetic field of the MRI. This review discusses the application of Ultralow-field portable MRI (ULF-pMRI), which operates at much lower magnetic field (0.064 T), with the potential to allow safe bedside imaging of critically ill patients. In this review, we detail the clinical studies and research findings defining the safety, feasibility, and diagnostic utility of ULF-pMRI in detecting ABI in the critically ill. We further discuss the potential broader applications of ULF-pMRI, as a standard diagnostic tool for neurocritical care in patients with cardiac devices. The integration of such technology into current practice promises to enhance diagnostic accuracy, improve patient outcomes, and optimize healthcare resources.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":"277-282"},"PeriodicalIF":3.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143063325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0