ASAIO Journal最新文献

Upper-Body Versus Femoral Return in Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation: A Systematic Review and Meta-analysis. 外周静脉-动脉体外膜氧合中上肢与股骨回流：系统回顾和荟萃分析。

IF 2.2 3区医学

ASAIO Journal Pub Date : 2026-09-03 DOI: 10.1097/MAT.0000000000002842

Saif-Eddin Dabour, Diya Asad, Abdullah Kouli, Elmustafa Hamed, Sana Tahir, Matthew Frank, Waqas Ullah

{"title":"Upper-Body Versus Femoral Return in Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation: A Systematic Review and Meta-analysis.","authors":"Saif-Eddin Dabour, Diya Asad, Abdullah Kouli, Elmustafa Hamed, Sana Tahir, Matthew Frank, Waqas Ullah","doi":"10.1097/MAT.0000000000002842","DOIUrl":"https://doi.org/10.1097/MAT.0000000000002842","url":null,"abstract":"Upper-body peripheral arterial return is used during veno-arterial extracorporeal membrane oxygenation (VA-ECMO), but its clinical tradeoffs versus femoral return are uncertain. We reviewed observational studies comparing upper-body to femoral arterial return for peripheral VA-ECMO in cardiogenic shock and related rescue states. Seven retrospective cohorts (2,987 patients) were included. Upper-body return included axillary, subclavian, and combined approaches with direct and graft-mediated techniques. In the primary short-term mortality analysis (five studies; 2,317 patients), mortality did not differ significantly between upper-body and femoral return (odds ratio [OR]: 1.01, 95% confidence interval [CI]: 0.62-1.65; p = 0.96; I2 = 44%). In crude pooled analyses, upper-body return was associated with higher ischemic stroke (six studies; OR: 1.78, 95% CI: 1.31-2.42; p = 0.005; I2 = 0%), hemorrhagic stroke (four studies; OR: 2.34, 95% CI: 1.41-3.87; p = 0.01; I2 = 0%), and any stroke/cerebrovascular event (five studies; OR: 1.63, 95% CI: 1.28-2.09; p = 0.005; I2 = 0%). Limb ischemia was extremely imprecise and not statistically significant (three studies; OR: 0.34, 95% CI: < 0.01-44.78; p = 0.44; I2 = 82%). The available observational evidence does not suggest the superiority of either access strategy over the other. Given the heterogeneous data and stroke signal, the arterial return strategy should be individualized rather than broadly adopted as a default approach.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148886142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Feasibility and Midterm Outcomes of Concomitant Aortic Valve Plasty in Contemporary HeartMate 3 Practice. 主动脉瓣成形术的可行性和中期结果。

IF 2.2 3区医学

ASAIO Journal Pub Date : 2026-09-02 DOI: 10.1097/MAT.0000000000002817

Kohei Tonai, Kota Suzuki, Nana Kitahata, Kizuku Yamashita, Takuma Sato, Yasumasa Tsukamoto, Satsuki Fukushima

{"title":"Feasibility and Midterm Outcomes of Concomitant Aortic Valve Plasty in Contemporary HeartMate 3 Practice.","authors":"Kohei Tonai, Kota Suzuki, Nana Kitahata, Kizuku Yamashita, Takuma Sato, Yasumasa Tsukamoto, Satsuki Fukushima","doi":"10.1097/MAT.0000000000002817","DOIUrl":"https://doi.org/10.1097/MAT.0000000000002817","url":null,"abstract":"De novo aortic regurgitation (AR) remains a clinically significant complication of continuous-flow left ventricular assist device support, including the HeartMate 3 (HM3). Contemporary durability and safety data for concomitant aortic valve plasty (AVP) in HM3 recipients-particularly those bridged with temporary mechanical circulatory support (tMCS)-are limited. We retrospectively analyzed 115 consecutive adults undergoing primary HM3 implantation between August 2019 and December 2024; 35 (30%) received concomitant AVP. Time-to-event outcomes were estimated using Kaplan-Meier methods with a 30 day landmark and corroborated by Aalen-Johansen competing-risk cumulative incidence functions. One early technical failure (postoperative day 1) was excluded from the primary analysis, and one additional de novo event occurred during follow-up. Freedom from greater than or equal to moderate AR in the AVP cohort was 100% at 1 year and 94.7% (95% confidence interval [CI], 68.1-99.2) at 2-3 years; AR severity distributions remained stable, with no severe AR. Operative and cardiopulmonary bypass times were longer in the AVP group, whereas early hemodynamics and in-hospital and midterm adverse-event rates were comparable. These findings support selective concomitant AVP as a feasible valve-sparing strategy in contemporary HM3 practice, including tMCS-exposed recipients. Prospective multicenter studies are warranted to refine patient selection and to characterize long-term durability.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148879100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Noninvasive Respiratory Support Before Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome: A Meta-Analysis. 急性呼吸窘迫综合征体外膜氧合前无创呼吸支持：一项荟萃分析。

IF 2.2 3区医学

ASAIO Journal Pub Date : 2026-09-02 DOI: 10.1097/MAT.0000000000002833

Alberto Marabotti, Giovanni Cianchi, Pietro Bertini, Gianluca Paternoster, Fabio Sangalli, Marina Orlandi, Andrea Franci, Manuela Bonizzoli

{"title":"Noninvasive Respiratory Support Before Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome: A Meta-Analysis.","authors":"Alberto Marabotti, Giovanni Cianchi, Pietro Bertini, Gianluca Paternoster, Fabio Sangalli, Marina Orlandi, Andrea Franci, Manuela Bonizzoli","doi":"10.1097/MAT.0000000000002833","DOIUrl":"https://doi.org/10.1097/MAT.0000000000002833","url":null,"abstract":"The optimal timing for transitioning from noninvasive respiratory support to invasive mechanical ventilation and extracorporeal membrane oxygenation (ECMO) in severe acute respiratory distress syndrome (ARDS) remains controversial. PubMed and Embase were searched for studies reporting the duration of noninvasive respiratory support and the total duration of pre-ECMO respiratory support among survivors and non-survivors. A random-effects model with the Hartung-Knapp adjustment was used. Certainty of evidence was rated using the GRADE approach. Ten studies involving 718 patients were included. Survivors spent significantly fewer days on noninvasive respiratory support before ECMO (mean difference [MD]: -1.88 days [95% confidence interval (CI): -2.81 to -0.96]; p < 0.01), with a 95% prediction interval (PI) ranging from -3.71 to -0.05; GRADE certainty: Low. In the total pre-ECMO respiratory support duration (noninvasive plus invasive) analysis, the MD widened to -3.49 days (95% CI: -6.20 to -0.78, p = 0.03), with a PI ranging from -8.04 to 1.06; GRADE certainty: Very Low. These data suggest that the duration of pre-ECMO noninvasive respiratory support could jeopardize the success of the treatment; however, they are based on observational studies and should be considered hypothesis-generating, advocating further research on this topic.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148879136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of Extracorporeal Membrane Oxygenation (ECMO) in Pediatric Patients With Hemophagocytic Lymphohistiocytosis: A Multicenter Sub-Analysis. 体外膜氧合（ECMO）在小儿噬血细胞淋巴组织细胞症患者中的应用：一项多中心亚分析。

IF 2.2 3区医学

ASAIO Journal Pub Date : 2026-09-02 DOI: 10.1097/MAT.0000000000002831

Rohit P Nair, Michael C Mowrer, David Farbo, James A Thomas, Andrea Ontaneda, Saad Ghafoor, Renee M Potera, Lakshmi Raman, Saleh Bhar

{"title":"Use of Extracorporeal Membrane Oxygenation (ECMO) in Pediatric Patients With Hemophagocytic Lymphohistiocytosis: A Multicenter Sub-Analysis.","authors":"Rohit P Nair, Michael C Mowrer, David Farbo, James A Thomas, Andrea Ontaneda, Saad Ghafoor, Renee M Potera, Lakshmi Raman, Saleh Bhar","doi":"10.1097/MAT.0000000000002831","DOIUrl":"https://doi.org/10.1097/MAT.0000000000002831","url":null,"abstract":"Hemophagocytic lymphohistiocytosis (HLH) is a rare condition causing severe systemic inflammatory activation, cytokine storm, and multiorgan dysfunction for which extracorporeal membrane oxygenation (ECMO) may be required. There is a paucity of data to guide clinicians in the care of these patients; we aimed to address this need. From the Hematology and Oncology Pediatric Patients on ECMO (HOPPE) database, 30 patients diagnosed with HLH were identified from 13 of the 16 total participating centers between 2009 and 2021. Of those 30 patients, 63% survived to ECMO decannulation, 43% to ICU discharge, and 37% to hospital discharge. Among survivors, there was a median of 44.9 days between decannulation and hospital discharge. Half of the ECMO mortality occurred within the first 10 days on ECMO. Patients who survived to hospital discharge also had evidence of functional limitation and significant multiorgan dysfunction. A total of 90% of patients diagnosed with HLH on ECMO survived to decannulation vs. 50% of patients diagnosed before. Survival has improved in this patient population compared to previous literature but is still lower than the overall pediatric ECMO population. Clinical suspicion for HLH in these critically ill patients should not exclude them from escalation of support, including ECMO.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148879116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early Lactate Trajectories and Outcomes in Veno-Arterial Extracorporeal Membrane Oxygenation-Supported Cardiogenic Shock: A Multicenter Study. 静脉-动脉体外膜氧合支持的心源性休克的早期乳酸轨迹和结局：一项多中心研究。

IF 2.2 3区医学

ASAIO Journal Pub Date : 2026-09-02 DOI: 10.1097/MAT.0000000000002837

Zhe Li, Wan Chen, Chenglong Li, Lei Shi, Guozheng Qiu, Wenlong Duan, Mingyu Pei, Yao Zhou, Bo Wang, Xiaotong Hou, Liwen Lyu

{"title":"Early Lactate Trajectories and Outcomes in Veno-Arterial Extracorporeal Membrane Oxygenation-Supported Cardiogenic Shock: A Multicenter Study.","authors":"Zhe Li, Wan Chen, Chenglong Li, Lei Shi, Guozheng Qiu, Wenlong Duan, Mingyu Pei, Yao Zhou, Bo Wang, Xiaotong Hou, Liwen Lyu","doi":"10.1097/MAT.0000000000002837","DOIUrl":"https://doi.org/10.1097/MAT.0000000000002837","url":null,"abstract":"In this multicenter retrospective study (Chinese Society of Extracorporeal Life Support [CSECLS] registry), we evaluated early lactate trajectories in 1,465 adults with cardiogenic shock surviving greater than 24 hours on veno-arterial extracorporeal membrane oxygenation (VA-ECMO). Unsupervised k-means clustering of serial lactates (baseline, 4 hours, 24 hours) defined four metabolic phenotypes. The \"Persistent High\" phenotype (5.7%) exhibited refractory hyperlactatemia (median 24 hour lactate 17.0 mmol/L) and the highest in-hospital mortality (85.7% vs. 27.9% in the \"Low Stable\" group; p < 0.001). Notably, this persistent hyperlactatemia occurred despite comparable ECMO flow indices (2.8 vs. 2.6 L/min/m2) and preserved venous oxygen saturation (72.2% ≥ 50%). The \"Persistent High\" trajectory independently predicted mortality (adjusted hazard ratio [HR]: 6.36, 95% confidence interval [CI]: 4.83-8.36) and severe organ failure, with findings reproduced in an external validation cohort (MIMIC-IV, n = 136). In conclusion, persistent hyperlactatemia during VA-ECMO may reflect impaired systemic oxygen utilization rather than insufficient macrocirculatory flow. Early trajectory-based phenotyping helps identify a refractory state of flow-metabolism decoupling, signaling a high-risk subgroup where conventional flow escalation alone may be insufficient.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148879084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fluoroscopic-Guided Decannulation of a Femoral Venous Extracorporeal Membrane Oxygenation Cannula Traversing an Inferior Vena Cava Filter. 透视引导下经下腔静脉过滤器的股静脉体外膜氧合套管脱管。

IF 2.2 3区医学

ASAIO Journal Pub Date : 2026-09-02 DOI: 10.1097/MAT.0000000000002830

Soojin Lee, Ho Seong Cho

{"title":"Fluoroscopic-Guided Decannulation of a Femoral Venous Extracorporeal Membrane Oxygenation Cannula Traversing an Inferior Vena Cava Filter.","authors":"Soojin Lee, Ho Seong Cho","doi":"10.1097/MAT.0000000000002830","DOIUrl":"https://doi.org/10.1097/MAT.0000000000002830","url":null,"abstract":"In patients with an indwelling inferior vena cava (IVC) filter who require venoarterial (VA) extracorporeal membrane oxygenation (ECMO), placement of a femoral venous drainage cannula may cause the two devices to become mechanically engaged. This configuration heightens the risk of complications at both cannulation and decannulation, including IVC filter migration, fracture, or venous injury. Despite this clinical challenge, reports describing safe VA ECMO decannulation approaches in patients with indwelling IVC filters are scarce; consequently, procedural guidance remains limited. We report the case of a patient with extensive pulmonary thromboembolism who underwent surgical pulmonary thrombectomy and IVC filter placement, followed by extracorporeal cardiopulmonary resuscitation (ECPR) for refractory cardiac arrest. Venoarterial ECMO was established using femoral cannulation with a venous drainage cannula traversing through the IVC filter. After weaning from VA ECMO, the femoral venous cannula was safely removed under fluoroscopic guidance on ECMO day 10 with no procedural complications. When decannulation of VA ECMO is required in patients with an indwelling IVC filter through which the femoral venous cannula traverses, fluoroscopy-guided decannulation can represent a safe and feasible strategy.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148879074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigating Aortic Root Hemodynamics With EVAHEART2 Pump Speed Modulation. 用EVAHEART2泵调速研究主动脉根部血流动力学。

IF 2.2 3区医学

ASAIO Journal Pub Date : 2026-09-01 Epub Date: 2025-10-15 DOI: 10.1097/MAT.0000000000002577

Jasmine Martinez, Ruth White, Vikash Shukla, Benjamin Diaz, Kelsey Smegner, Shinji Kobayashi, Tadashi Motomura, Venkat Keshav Chivukula

{"title":"Investigating Aortic Root Hemodynamics With EVAHEART2 Pump Speed Modulation.","authors":"Jasmine Martinez, Ruth White, Vikash Shukla, Benjamin Diaz, Kelsey Smegner, Shinji Kobayashi, Tadashi Motomura, Venkat Keshav Chivukula","doi":"10.1097/MAT.0000000000002577","DOIUrl":"10.1097/MAT.0000000000002577","url":null,"abstract":"Left ventricular assist device (LVAD) therapy often reduces the chances of aortic valve opening (AVO), increasing the risk of blood stagnation and thrombus formation. The EVAHEART2 (EVA2) pump speed modulation (PSM) can be leveraged to mitigate these risks by encouraging AVO. Study aims to i) investigate how PSM impacts aortic root hemodynamics, ii) quantify how much transaortic valve flow is needed to washout the aortic root, and iii) evaluate how PSM may alter pulsatility in LVAD flow. Computational fluid dynamics simulations were used to quantify aortic root washout, washout progression, and perform platelet tracking to evaluate thrombogenic potential. Results showed that when the aortic valve (AV) was closed, only 60% of blood was washed out after 4 seconds, whereas AVO significantly increased washout efficiency, clearing over 80% of blood within 3 seconds. Platelet tracking revealed that platelets were up to 60% more likely to stagnate for a nonfunctional AV compared with transaortic flow scenarios. Higher transaortic flow had the lowest thrombogenic potential score. These findings demonstrate that transaortic valve flow is the primary factor driving aortic root washout. Using EVA2 PSM settings to enhance transaortic valve flow can improve aortic root washout. This study emphasizes the importance of strategies that enable LVAD patients to have a functional AV.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":"740-749"},"PeriodicalIF":2.2,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145290710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hemolysis During Microaxial Flow Pump Support: Cause or Marker of Hemocompatibility-Related Adverse Events After Left Ventricular Assist Device Implantation? 微轴流泵支持期间溶血：左心室辅助装置植入后血液相容性相关不良事件的原因或标志？

IF 2.2 3区医学

ASAIO Journal Pub Date : 2026-09-01 Epub Date: 2026-07-07 DOI: 10.1097/MAT.0000000000002791

Toshihide Izumida, Teruhiko Imamura

引用次数: 0

Response to Letter to the Editor Regarding the Article "Parallel Dual-Lumen Venovenous Extracorporeal Membrane Oxygenation Following Extracorporeal Cardiopulmonary Resuscitation". 关于《体外心肺复苏后平行双腔静脉-静脉体外膜氧合》一文致编辑的回复

IF 2.2 3区医学

ASAIO Journal Pub Date : 2026-09-01 Epub Date: 2026-06-29 DOI: 10.1097/MAT.0000000000002749

Elliott Worku, Sridevi Shetty, Paul Forrest, Paul Torzillo, Richard Totaro

引用次数: 0

Experience With Pediatric Extracorporeal Membrane Oxygenation Standby at Two High-Volume Centers. 两个大容量中心的儿科体外膜氧合（ECMO）备用经验。

IF 2.2 3区医学

ASAIO Journal Pub Date : 2026-09-01 Epub Date: 2025-10-31 DOI: 10.1097/MAT.0000000000002592

Christopher Nemeh, Goeto Dantes, Caitlin Cain-Trivette, Kathryn Steklac, Nicholas Schmoke, Hilary R Jessup, Darina Kirilina, Paul Kurlansky, Caleb Varner, Michael Brewer, Eunice Clark, William Middlesworth, Allison F Linden, Eva W Cheung

{"title":"Experience With Pediatric Extracorporeal Membrane Oxygenation Standby at Two High-Volume Centers.","authors":"Christopher Nemeh, Goeto Dantes, Caitlin Cain-Trivette, Kathryn Steklac, Nicholas Schmoke, Hilary R Jessup, Darina Kirilina, Paul Kurlansky, Caleb Varner, Michael Brewer, Eunice Clark, William Middlesworth, Allison F Linden, Eva W Cheung","doi":"10.1097/MAT.0000000000002592","DOIUrl":"10.1097/MAT.0000000000002592","url":null,"abstract":"Extracorporeal membrane oxygenation (ECMO) can provide an option for high-risk procedures that may result in cardiopulmonary collapse. The indications for ECMO standby are not well delineated. We describe the experiences of pediatric ECMO standby at two high-volume centers. A retrospective review of pediatric ECMO standby from 2016 to 2023 was performed (n = 394). Data regarding the locations of ECMO standby and the types of procedures were obtained. The primary outcome evaluated was requiring ECMO cannulation during standby. Of the 394 pediatric patients, only 8 (2%) required ECMO cannulation during standby. The indications for ECMO standby were cardiac (84%) and respiratory (16%) complications. Standby locations included the cardiac catheterization suite (55.6%), the operating room (OR) (20.6%), the intensive care unit (ICU) (11.9%), and the interventional radiology (IR) suite (11.9%). Standby within the cardiac catheterization suite included diagnostic only (53%) and interventional (47%), of which 0 and 4 (3.9%) patients required ECMO, respectively. Procedures in OR, IR, or ICU consisted of major surgical procedures (14%), minimally invasive minor procedures (64%), intubations (18%), and transfers/births (4%). Few ECMO standby patients require cannulation; however, it is complicated to predict patient decompensation. Further studies are warranted to delineate which patients would benefit from ECMO standby while balancing cost and resource utilization.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":"786-791"},"PeriodicalIF":2.2,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145408024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0